Symmetrical cell tissue centrifuge

Abstract

The present application provides a symmetrical cell tissue centrifuge, comprising a rotatable centrifugal disk, the centrifugal disk comprising a central rotating seat, the central rotating seat being provided with a plurality of rotating arm devices symmetrically arranged in pairs along the circumference, the angles between adjacent rotating arm devices being equal, the rotating arm devices comprising a rotating arm frame, one end of the rotating arm frame being connected to the central rotating seat, the other end of the rotating arm frame being provided with a swingable loading platform, the loading platform being used for placing a film preparation chamber, thereby solving the problem of asymmetric rotating arm centrifuges, which has the problem of more troublesome counterweight placement.

Description

Technical Field

[0001] The present invention relates to the field of biological detection, in particular to a symmetrical cell tissue centrifuge. Background Art

[0002] After collection, the cervical cell sample is transferred to the liquid reservoir of the preparation chamber and the necessary reagents are added. The chamber is then placed in a centrifuge for centrifugal rotation. A centrifuge is a common laboratory device that spins the carrier to centrifuge the material, separating liquids and solids. This allows the sample to be quickly attached to the slide at the bottom of the chamber, completing the preparation.

[0003] To meet peak testing schedules, centrifuges are typically equipped with multiple arms, allowing multiple chambers to be centrifuged simultaneously during a single run. However, when centrifuging a single or small number of chambers, some of the chambers may not be fully filled, causing the centrifugal disc's center of gravity to be offset from the axis of rotation. This results in poor dynamic balance and vibration at high speeds.

[0004] In order to counterweight the centrifugal disc, the position and number of counterweights required for the asymmetric centrifugal disc with an asymmetrical rotating arm are uncertain. Since the inspection workstation generally uses an automated robot, it is difficult to program and debug with this uncertainty. It may even require additional visual recognition and customized special programs, which is costly and labor-intensive. Summary of the Invention

[0005] The present invention provides a symmetrical cell tissue centrifuge, which solves the problem of troublesome placement of counterweights in centrifuges with asymmetrical rotating arms.

[0006] In order to solve the above technical problems, the technical solution adopted by the present invention is: a symmetrical cell tissue centrifuge, including a rotatable centrifugal disk, the centrifugal disk includes a central rotating seat, the central rotating seat is provided with a plurality of rotating arm devices symmetrically arranged in pairs along the circumference, and the angles between adjacent rotating arm devices are equal. The rotating arm device includes a rotating arm frame, one end of the rotating arm frame is connected to the central rotating seat, and the other end of the rotating arm frame is provided with a swingable loading platform, which is used to place the film preparation chamber.

[0007] In the preferred solution, the rotating arm is provided with a through groove along the length direction, a central pedestal is provided at the center of the central rotating seat, a ball is provided on the central pedestal, a floating frame is provided at the end of the rotating arm away from the central rotating seat, and a lever is provided on one side of each rotating arm, the middle part of which is hinged to the rotating arm. The rotating arm device rotates to make the floating frame squeeze one end of the lever, and a push rod is provided at the other end of the lever, which pushes the ball toward the rotating arm on the opposite side.

[0008] In the preferred solution, an oblique extension frame is provided at the end of the rotating arm frame, the floating frame is slidably connected to the oblique extension frame, a first spring is provided between the floating frame and the oblique extension frame, a pressing plate is provided at the lower end of the floating frame, a sleeve hole is provided at the lower end of the pressing plate, the sleeve hole is sleeved with the end of the lever, the diameter of the sleeve hole is larger than the diameter of the end of the lever, and a plurality of through holes are provided at the lower end of the central base, each through hole is used for each push rod to pass through.

[0009] In the preferred solution, a limit cover is further provided at one end of the rotating arm away from the central rotating seat, a accommodating cavity is provided in the limit cover, a telescopic block is provided at the bottom end of the through slot in the accommodating cavity, a wedge-shaped surface is provided at the upper end of the telescopic block close to the central rotating seat, a second spring is provided between the telescopic block and the bottom end of the through slot, a pressure rod is provided at the lower end of the telescopic block, and the lower end of the pressure rod rests against the outer wall of the lever.

[0010] In a preferred solution, an adjustment sleeve is provided at one end of the pressure rod away from the lever, the pressure rod is threadedly connected to the adjustment sleeve, and a third spring is provided at one end of the adjustment sleeve.

[0011] In the preferred solution, the end of the through slot away from the central rotating seat is higher than the end close to the central rotating seat. The central seat is provided with multiple radial guide rolling grooves, which are connected to the through slot, and the end of the guide rolling groove away from the center is higher.

[0012] In the preferred solution, a central pit is provided at the center of the central pedestal, and the guide rolling groove is connected to the central pit.

[0013] In a preferred solution, retaining walls are provided on both sides of the guide rolling groove.

[0014] In a preferred solution, a guide sliding portion is provided at the lower end of the central pedestal, the guide sliding portion is slidably connected to the central rotating seat, a fourth spring is provided in the guide sliding portion, and one end of the fourth spring rests on the central rotating seat.

[0015] The beneficial effects of the present invention are as follows: the symmetrical design of the rotating arm is adopted, and only one counterweight needs to be added on the opposite side of the film production chamber. The placement position and quantity are determined, and it is easy to program automatically; balls are arranged inside the device, and the rotating arm that needs counterweight is automatically found and rolled to the corresponding position by relying on centrifugal force. The weight can be automatically counterweighted without manual or external mechanisms, with low cost and high fault tolerance; not only can dynamic balance in the horizontal direction be achieved, but also the center of gravity on both sides can be kept consistent in the height direction, thereby preventing unnecessary bending moment on the drive motor or the connecting shaft and improving dynamic balance during centrifugation; a slope surface with a high outside and a low inside is adopted to guide the rolling of the balls. After the centrifugal rotation is completed, the balls automatically return to the center by gravity, thereby ensuring the stability and reliability of the next counterweight. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The present invention will be further described below with reference to the accompanying drawings and examples.

[0017] Figure 1 It is a schematic diagram of the present invention.

[0018] Figure 2 Schematic diagram of the centrifugal disk of the present invention.

[0019] Figure 3 It is a diagram of the internal structure of the centrifugal disk of the present invention.

[0020] Figure 4 It is a schematic diagram of the middle part of the centrifugal disk of the present invention.

[0021] Figure 5 It is a schematic diagram of the lower part of the rotating arm device of the present invention.

[0022] Figure 6 It is a top view of the centrifugal disk of the present invention.

[0023] Figure 7 It is a cross-sectional view of the centrifugal disk of the present invention.

[0024] Figure 8 It is a cross-sectional view of the central pedestal of the present invention.

[0025] Figure 9 It is a cross-sectional view of the central pedestal through hole of the present invention.

[0026] Figure 10 It is a schematic diagram of the central pedestal of the present invention.

[0027] Figure 11 It is a side sectional view of the limiting cover of the present invention.

[0028] Figure 12 It is a front cross-sectional view of the limiting cover of the present invention.

[0029] Figure 13 It is a structural diagram of the floating frame of the present invention.

[0030] Figure 14 It is a structural diagram of the limiting cover of the present invention.

[0031] Figure 15 It is a schematic diagram of height imbalance of the present invention.

[0032] In the figure: centrifuge base 1; centrifugal disc 2; central rotating seat 201; clamping column 202; rotating arm device 3; rotating arm frame 301; oblique frame clamping groove 302; rotating arm mounting groove 303; through groove 304; push rod 305; lever 306; limiting cover 307; telescopic block 308; wedge surface 309; pressure rod 310; second spring 311; adjustment sleeve 312; third spring 313; centrifugal drive motor 4; docking sleeve 5; oblique frame 6; loading platform 601; floating frame 602; pressing plate 603; sleeve hole 604; first spring 605; central base 7; retaining wall 701; guide rolling groove 702; central pit 703; through hole 704; fourth spring 705; guide sliding part 706; ball 8. DETAILED DESCRIPTION

[0033] like Figure 1-15 In the invention, a symmetrical cell tissue centrifuge includes a rotatable centrifugal disk 2, which includes a central rotating base 201. The central rotating base 201 is provided with a plurality of rotating arm devices 3 symmetrically arranged in pairs along the circumference, and the angles between adjacent rotating arm devices 3 are equal. The rotating arm device 3 includes a rotating arm frame 301, one end of the rotating arm frame 301 is connected to the central rotating base 201, and the other end of the rotating arm frame 301 is provided with a swingable loading platform 601, which is used to place the preparation chamber.

[0034] The number of arm devices 3 is an even number, such as four, six, or eight. Each arm device 3 is equipped with an arm device 3 on the opposite side, and the two are arranged in a straight line. Centrifuges with an even number of arms have the advantage of being easy to counterweight. When there is only one film production chamber, a counterweight of equal weight can be placed on the loading platform 601 of the opposite arm device 3. In contrast, centrifuges with an odd number of arms require multiple counterweights or all remaining empty spaces to restore dynamic balance if the film production chamber is small. For example, if only one film production chamber needs to be centrifuged, in the case of three or five arms, the loading platform 601 needs to be fully filled. In the case of nine arms, at least two additional film production chambers need to be added to form an equilateral triangle for normal operation.

[0035] Since the number of compensating weights varies in different situations, especially for automated compensation, the compensation difficulty of a centrifuge with a symmetrically arranged even-numbered rotating arms is much lower than that of a centrifuge with an odd-numbered rotating arms.

[0036] The counterweight can be a film making chamber with the same mass as the sample or other weights of the same mass.

[0037] A centrifuge base 1 is further provided, on which a centrifugal drive motor 4 is provided. The centrifugal drive motor 4 is connected to the central rotating base 201 through a docking sleeve 5 , and the centrifugal drive motor 4 drives the centrifugal disc 2 to rotate.

[0038] In the preferred embodiment, the rotating arm 301 is provided with a through groove 304 along the length direction, a central pedestal 7 is provided at the center of the central rotating seat 201, and a ball 8 is provided on the central pedestal 7. A floating frame 602 is provided at the end of the rotating arm 301 away from the central rotating seat 201, and a lever 306 is provided on one side of each rotating arm 301, the middle of which is hinged to the rotating arm 301. The rotating arm device 3 rotates so that the floating frame 602 squeezes one end of the lever 306, and the other end of the lever 306 is provided with a push rod 305, which pushes the ball 8 toward the rotating arm 301 on the opposite side.

[0039] One end of the rotating arm 301 is provided with a rotating arm mounting groove 303, which is clamped on the clamping column 202. The side wall of the through groove 304 is provided with multiple oblique extension frame clamping grooves 302, and one end of the oblique extension frame 6 is clamped in the oblique extension frame clamping groove 302.

[0040] The eccentric ball 8 rolls to the end along the through slot 304 of the opposite rotating arm 301 due to the action of centrifugal force. Since it cannot roll to a position as far as the film making chamber, the force arm of the ball 8 relative to the rotation center is slightly shorter than that of the film making chamber. The weight of the ball 8 is slightly larger than that of the film with the sample, so the total torque on both sides can be equal. In this way, the two rotating arm devices 3 can ensure the symmetry of the center of gravity.

[0041] In the preferred solution, an oblique extension frame 6 is provided at the end of the rotating arm 301, the floating frame 602 is slidably connected to the oblique extension frame 6, a first spring 605 is provided between the floating frame 602 and the oblique extension frame 6, a pressing plate 603 is provided at the lower end of the floating frame 602, a sleeve hole 604 is provided at the lower end of the pressing plate 603, the sleeve hole 604 is sleeved with the end of the lever 306, the diameter of the sleeve hole 604 is larger than the diameter of the end of the lever 306, and a plurality of through holes 704 are provided at the lower end of the central pedestal 7, each through hole 704 is used for each push rod 305 to pass through.

[0042] Because the extended frame 6 is arranged at an angle, centrifugal force causes the floating frame 602 to compress the push rod 305 and move it downward during rotation. The sleeve 604 presses down on the end of the lever 306, causing the push rod 305 to move upward through the through hole 704 and push against the lower end of the ball 8, causing the ball 8 to roll to the other side. If the ball 8 becomes off-center, the centrifugal force acts on the ball 8, causing it to continue moving to the opposite side until it is stopped by the end of the through slot 304.

[0043] When there are film making chambers in all the loading platforms 601, all the push rods 305 will be lifted and at the same height. Although the ball 8 is lifted, the ball 8 is still stuck in the middle due to the circumferential arrangement of the push rods 305 and will not be eccentric.

[0044] Although the ball bearing 8 is used to balance the weight of the extra film-making chamber on the opposite side, it is only balanced in the horizontal direction. If the center of gravity of the ball bearing 8 is close to the same height as the weight of the loading platform 601 and the film-making chamber on the opposite side, since there is no film-making chamber on the loading platform 601 on this side, its height is higher than the loading platform 601 on the opposite side. At this time, although it is balanced horizontally, a force couple will still be generated on the central axis in terms of height, causing bending moment on the motor shaft and generating vibration.

[0045] In the preferred embodiment, a limit cover 307 is further provided at the end of the rotating arm 301 away from the central rotating seat 201, and a accommodating cavity is provided in the limit cover 307. A telescopic block 308 is provided at the bottom end of the through slot 304 in the accommodating cavity, and a wedge-shaped surface 309 is provided at the upper end of the telescopic block 308 on the side close to the central rotating seat 201. A second spring 311 is provided between the telescopic block 308 and the bottom end of the through slot 304. A pressure rod 310 is provided at the lower end of the telescopic block 308, and the lower end of the pressure rod 310 rests against the outer wall of the lever 306.

[0046] The position where the pressure rod 310 abuts and the position where the pressure plate 603 abuts are the same end of the lever 306. When the ball 8 rolls into the accommodating cavity, the left and right sides and the upper side are limited to prevent it from flying out due to excessive centrifugal force.

[0047] The telescopic block 308 is inserted into the chute at the bottom of the through slot 304. The ball 8 abuts against and presses against the wedge surface 309, causing the telescopic block 308 to retract, forcing the ball 8 to continue moving forward for a distance until the centrifugal force component is counteracted by the retaining force of the second spring 311, rebalancing the ball 8. At this point, the pressure rod 310 pushes down on the lever 306, pulling the pressure plate 603 downward, pressing the floating frame 602 downward. This reduces the angle of the wedge surface 309, resulting in less outward movement of the ball 8 and a greater downward movement of the floating frame 602, ultimately achieving equilibrium in both height and horizontal directions.

[0048] In a preferred solution, an adjustment sleeve 312 is provided at one end of the pressure rod 310 away from the lever 306 , the pressure rod 310 is threadedly connected to the adjustment sleeve 312 , and a third spring 313 is provided at one end of the adjustment sleeve 312 .

[0049] The telescopic block 308 is provided with at least three through holes, of which the middle one is a stepped countersunk hole for placing the adjustment sleeve 312 and the pressure rod 310. The ends of each hole are provided with threaded top screws to adjust the compression amount of each spring. The total length of the adjustment sleeve 312 and the pressure rod 310 is adjustable, which is convenient for finding a suitable extension length when debugging the pressure rod 310.

[0050] A accommodating cavity with a guide is provided in the middle of the limiting cover 307. The lower end of the limiting cover 307 is open. The upper side and left and right sides of the limiting ball 8 are provided with snap-fitting protrusions on both sides, which can be snapped onto the side wall of the rotating arm 301. A through groove is provided on the upper end surface to facilitate the passage of the wrench. A limiting protrusion is provided on the inner top wall of the accommodating cavity to prevent the telescopic block 308 from falling off upward.

[0051] In the preferred embodiment, the end of the through groove 304 away from the central rotating seat 201 is higher than the end close to the central rotating seat 201. A plurality of radial guide rolling grooves 702 are provided on the central base 7. The guide rolling grooves 702 are docked with the through groove 304, and the end of the guide rolling groove 702 away from the center is higher.

[0052] During rotation, the ball 8 can roll to the end along the guide rolling groove 702 and the through groove 304 . When the rotation stops, the ball 8 can return to the center of the central pedestal 7 along the slope surface.

[0053] In a preferred solution, a central recess 703 is provided at the center of the central pedestal 7 , and the guide rolling groove 702 is docked with the central recess 703 .

[0054] When there is no need for counterweight, the central recess 703 allows the ball 8 to stop stably at the center of the central base 7 to prevent eccentricity due to unevenness of the device.

[0055] In a preferred solution, retaining walls 701 are provided on both sides of the guide rolling groove 702 .

[0056] The retaining wall 701 assists the guide rolling groove 702 to prevent the ball 8 from escaping laterally due to excessive centrifugal force when passing through.

[0057] In the preferred embodiment, a guide sliding portion 706 is provided at the lower end of the central pedestal 7 , and the guide sliding portion 706 is slidably connected to the central rotating seat 201 . A fourth spring 705 is provided in the guide sliding portion 706 , and one end of the fourth spring 705 rests on the central rotating seat 201 .

[0058] When the ball 8 is on the central pedestal 7, the central pedestal 7 sinks a little and forms a step with the central rotating base 201. At this time, the ball 8 will not leave the range of the central pedestal 7. When the ball 8 is eccentric and the device rotates to a certain angular velocity, the ball 8 can cross the step and reach the through groove 304. The upper end of the central pedestal 7 can be covered to cooperate with the step to prevent the ball 8 from entering the through groove 304 during transportation or low-speed rotation and debugging.

[0059] The above embodiments are merely preferred technical solutions of the present invention and should not be construed as limiting the present invention. The scope of protection of the present invention shall be the technical solutions set forth in the claims, including equivalent alternatives to the technical features of the technical solutions set forth in the claims. In other words, equivalent alternatives and improvements within this scope are also within the scope of protection of the present invention.

Claims

1. A symmetrical cell tissue centrifuge, characterized by: Including A rotating centrifugal disc (2), the centrifugal disc (2) comprising a central rotating seat (201), the central rotating seat (201) being provided with a plurality of rotating arm devices (3) symmetrically arranged in pairs along the circumference, the included angles between adjacent rotating arm devices (3) being equal, the rotating arm devices (3) comprising a rotating arm frame (301), one end of the rotating arm frame (301) being connected to the central rotating seat (201), the other end of the rotating arm frame (301) being provided with a swingable loading platform (601), the loading platform (601) being used for placing a film making chamber; The rotating arm (301) is provided with a through slot (304) along the length direction, a central pedestal (7) is provided at the center of the central rotating seat (201), a ball (8) is provided on the central pedestal (7), a floating frame (602) is provided at one end of the rotating arm (301) away from the central rotating seat (201), and a lever (306) is provided on one side of each rotating arm (301) whose middle portion is hinged to the rotating arm (301), the rotating arm device (3) rotates so that the floating frame (602) squeezes one end of the lever (306), and a push rod (305) is provided at the other end of the lever (306), and the push rod (305) pushes the ball (8) toward the rotating arm (301) on the opposite side; An oblique extension frame (6) is provided at the end of the rotating arm frame (301), a floating frame (602) is slidably connected to the oblique extension frame (6), a first spring (605) is provided between the floating frame (602) and the oblique extension frame (6), a pressing plate (603) is provided at the lower end of the floating frame (602), a sleeve hole (604) is provided at the lower end of the pressing plate (603), the sleeve hole (604) is sleeved with the end of the lever (306), the diameter of the sleeve hole (604) is larger than the diameter of the end of the lever (306), and a plurality of through holes (704) are provided at the lower end of the central pedestal (7), each through hole (704) is used for each push rod (305) to pass through.

2. The symmetrical cell tissue centrifuge according to claim 1, characterized in that: A limit cover (307) is further provided at one end of the rotating arm (301) away from the central rotating seat (201), and a receiving chamber is provided in the limit cover (307). A telescopic block (308) is provided at the bottom end of the through slot (304) in the receiving chamber, and a wedge-shaped surface (309) is provided at the upper end of the telescopic block (308) on the side close to the central rotating seat (201). A second spring (311) is provided between the telescopic block (308) and the bottom end of the through slot (304). A pressure rod (310) is provided at the lower end of the telescopic block (308), and the lower end of the pressure rod (310) abuts against the outer wall of the lever (306).

3. The symmetrical cell tissue centrifuge according to claim 2, characterized in that: An adjustment sleeve (312) is provided at one end of the pressure rod (310) away from the lever (306), the pressure rod (310) and the adjustment sleeve (312) are threadedly connected, and a third spring (313) is provided at one end of the adjustment sleeve (312).

4. The symmetrical cell tissue centrifuge according to claim 1 or 2, characterized in that: The end of (304) away from the central rotating seat (201) is higher than the end close to the central rotating seat (201), and a plurality of radial guide rolling grooves (702) are provided on the central pedestal (7), the guide rolling grooves (702) are docked with the through grooves (304), and the end of the guide rolling grooves (702) away from the center is higher.

5. The symmetrical cell tissue centrifuge according to claim 4, characterized in that: A central recess (703) is provided at the center of the central pedestal (7), and the guide rolling groove (702) is butted against the central recess (703).

6. The symmetrical cell tissue centrifuge according to claim 4, characterized in that: Retaining walls (701) are provided on both sides of the guide rolling groove (702).

7. The symmetrical cell tissue centrifuge according to claim 1, characterized in that: A guide sliding portion (706) is provided at the lower end of the central pedestal (7), and the guide sliding portion (706) is slidably connected to the central rotating seat (201). A fourth spring (705) is provided in the guide sliding portion (706), and one end of the fourth spring (705) rests on the central rotating seat (201).

Images