Composition with whitening effect and application thereof
Through the combination of vitamin C, sea sandalwood seed oil and honey yeast/glucose/rapeseed methyl ester fermentation products, the problems of heavy metal hazards and photosensitivity in whitening products are solved, providing a stable and non-irritating whitening skin care solution.
Patent Information
- Application Number
- CN202310690513.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-06-12
- Publication Date
- 2025-09-09
- Estimated Expiration
- 2043-06-12
AI Technical Summary
Existing whitening products contain heavy metals, which are harmful to human health if used for a long time. In addition, the whitening ingredients are easily ineffective under strong light or high temperature, resulting in poor whitening effect.
It uses a combination of vitamin C, sea sandalwood seed oil and Candida albicans/glucose/rapeseed methyl ester fermentation products to achieve a synergistic whitening effect by inhibiting melanin transfer and relying on skin metabolism to excrete the melanin that has already been produced. The ingredients are stable and non-photosensitive.
It achieves a whitening effect without heavy metals and good stability. It still has a good whitening effect after long-term use and does not irritate the skin. It is suitable for skin care products and cosmetics.
Smart Images

Figure BDA0004280014250000081 
Figure BDA0004280014250000091 
Figure BDA0004280014250000111
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of daily chemicals, in particular to a composition with whitening effect and application thereof. Background Art
[0002] Many women consider white skin to be beautiful, and there are numerous whitening products on the market. However, most contain heavy metals like mercury and lead. Long-term use can cause these metals to penetrate the skin, causing significant harm to human health. Furthermore, the whitening ingredients in these products are often photosensitive and lose their effectiveness under strong sunlight or high temperatures, resulting in poor whitening results. Summary of the Invention
[0003] Based on this, it is necessary to provide a composition having a whitening effect that does not contain heavy metals and has good stability, and its application and cosmetics.
[0004] A first aspect of the present invention provides a composition with whitening effect, comprising vitamin C, safflower seed oil and a fermentation product of Candida albiflora / glucose / rapeseed oleic acid methyl ester.
[0005] In some embodiments, the mass ratio of the vitamin C, the maltodextrin seed oil, and the Candida albiflora / glucose / rapeseed methyl ester fermentation product is (0.1-5):(0.1-5):(0.05-3).
[0006] The second aspect of the present invention provides a use of the composition with whitening effect according to the first aspect of the present invention in the preparation of a skin care product with whitening effect.
[0007] The third aspect of the present invention provides a cosmetic with whitening effect, wherein the active ingredient of the cosmetic includes the composition with whitening effect according to the first aspect of the present invention.
[0008] In some embodiments, a moisturizer is also included;
[0009] Optionally, the moisturizing agent includes one or more of chitosan, glycerin, butylene glycol, propylene glycol, 1,2-pentanediol, phytosterol, dipropylene glycol, hexylene glycol, polyethylene glycol, panthenol, xylitol, sodium hyaluronate, glycerol polyether and methyl glucitol polyether;
[0010] Further optionally, the moisturizing agent comprises chitosan, sodium hyaluronate and 1,2-pentanediol in a mass ratio of (0.1-2):(0.1-0.3):(0.1-1.5).
[0011] In some embodiments, a thickener is also included;
[0012] Optionally, the thickener comprises one or more of carbomer, xanthan gum, gum arabic, polymer EMT-10, sodium acrylate / sodium acryloyldimethyltaurate, hydroxyethyl cellulose and agarose;
[0013] Further optionally, the thickener comprises carbomer and xanthan gum in a mass ratio of (0.1-0.15):(0.1-0.5).
[0014] In some embodiments, an emulsifier is also included;
[0015] Optionally, the emulsifier includes one or more of glyceryl stearate, PEG-100 stearate, PEG-400 dilaurate, PEG-400 monolaurate, PEG-12 lauryl ether, PEG-20 sorbitan monostearate and cetearyl glucoside;
[0016] Further optionally, the emulsifier includes glyceryl stearate.
[0017] In some embodiments, a preservative is also included;
[0018] Optionally, the preservative comprises one or more of phenoxyethanol, methylparaben, propylparaben, imidazolidinyl urea and DMDM hydantoin;
[0019] Further optionally, the preservative comprises phenoxyethanol.
[0020] In some embodiments, a skin conditioning agent is also included;
[0021] Optionally, the skin conditioning agent comprises dipotassium glycyrrhizate.
[0022] In some embodiments, the following components are included in percentage by mass:
[0023] 0.1%-5% vitamin C, 0.1%-5% maltodextrin seed oil, 0.05%-3% Candida albiflora / glucose / methyl rapeseed oil fermentation product, 0.1%-2% chitosan, 0.1%-0.3% sodium hyaluronate, 0.1%-0.15% carbomer, 0.1%-1.5% 1,2-pentanediol, 0.1%-0.3% phenoxyethanol, 1%-3% glyceryl stearate, 0.1%-0.5% dipotassium glycyrrhizate, 0.1%-0.5% xanthan gum, and the balance is deionized water.
[0024] In some embodiments, the following components are included in percentage by mass:
[0025] 5% vitamin C, 5% maltodextrin seed oil, 1% Candida albiflora / glucose / rapeseed methyl ester fermentation product, 1.5% chitosan, 0.2% sodium hyaluronate, 0.14% carbomer, 0.5% 1,2-pentanediol, 0.25% phenoxyethanol, 2.5% glyceryl stearate, 0.35% dipotassium glycyrrhizate, 0.35% xanthan gum, and the balance is deionized water.
[0026] The above-mentioned whitening composition, its application, and cosmetics include vitamin C, maltodendron salsa seed oil, and a fermentation product of Candida mellifera / glucose / rapeseed oleic acid methyl ester. Vitamin C has antioxidant properties and can inhibit melanin transfer; maltodendron salsa seed oil effectively promotes cell renewal; and the fermentation product of Candida mellifera / glucose / rapeseed oleic acid methyl ester promotes collagen absorption. The combination of vitamin C, maltodendron salsa seed oil, and the fermentation product of Candida mellifera / glucose / rapeseed oleic acid methyl ester addresses the root cause of the problem, inhibiting melanin transfer. The product then relies on the skin's own metabolic processes to excrete any melanin produced, achieving a synergistic whitening effect. Furthermore, each ingredient is non-photosensitive, stable, completely mild, and non-irritating. DETAILED DESCRIPTION
[0027] To facilitate understanding of the present invention, the present invention will be described more fully below with reference to the relevant embodiments. Preferred embodiments of the present invention are provided below. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, the purpose of providing these embodiments is to provide a more thorough and comprehensive understanding of the disclosure of the present invention.
[0028] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used in this specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention.
[0029] In the present invention, the technical features described in an open manner include closed technical solutions composed of the listed features, and also include open technical solutions containing the listed features.
[0030] In the present invention, when referring to numerical ranges, unless otherwise specified, the numerical ranges are considered continuous and include the minimum and maximum values of the range, as well as every value between such minimum and maximum values. Furthermore, when a range refers to an integer, every integer between the minimum and maximum values of the range is included. In addition, when multiple ranges are provided to describe a feature or characteristic, the ranges can be combined. In other words, unless otherwise specified, all ranges disclosed herein should be understood to include any and all subranges subsumed therein.
[0031] Only certain numerical ranges are specifically disclosed herein. However, any lower limit may be combined with any upper limit to form an unspecified range; and any lower limit may be combined with other lower limits to form an unspecified range, and similarly, any upper limit may be combined with any other upper limit to form an unspecified range. In addition, each individually disclosed point or single value may itself serve as a lower limit or upper limit and be combined with any other point or single value, or with other lower limits or upper limits, to form an unspecified range.
[0032] The temperature parameters in the present invention, unless otherwise specified, allow for either constant temperature treatment or treatment within a certain temperature range. The constant temperature treatment allows for temperature fluctuations within the precision range controlled by the instrument.
[0033] In the description of the invention, “plurality” means at least two, for example, two, three, etc., unless otherwise clearly and specifically defined.
[0034] Unless otherwise specified, all embodiments and optional embodiments of the present invention can be combined with each other to form a new technical solution. Unless otherwise specified, all technical features and optional technical features of the present invention can be combined with each other to form a new technical solution.
[0035] Unless otherwise specified, all steps of the present invention may be performed sequentially or randomly, but are preferably performed sequentially.
[0036] A first aspect of the present invention provides a composition with whitening effect, comprising vitamin C, safflower seed oil and a fermentation product of Candida albiflora / glucose / rapeseed oleic acid methyl ester.
[0037] Vitamin C is a polyhydroxy compound with the chemical formula C6H8O6. Its structure is similar to glucose. The two adjacent enol hydroxyl groups at the 2nd and 3rd positions in its molecule are very easy to dissociate and release H + , so it has the properties of acid, also known as ascorbic acid; Vitamin C has excellent antioxidant and free radical scavenging capabilities, and has the functions of whitening, inhibiting melanin transfer, and anti-aging in the skin.
[0038] Sea sandalwood seed oil has a delicate and velvety texture on the skin and has strong moisturizing ability. It also contains a high content of monounsaturated fatty acids, including ximenynic acid, tocotrienol, lupeol and β-amyrin, which can repair the skin barrier, promote cell renewal, and make the skin smoother and firmer. At the same time, sea sandalwood seed oil has high antioxidant stability and can effectively delay skin aging.
[0039] The fermentation product of Candida albicans / glucose / rapeseed methyl ester can promote the penetration of the collagen composition into the skin, improve the permeability of the collagen composition, regulate the water and oil balance of the skin, soften the keratin, improve the skin's ability to absorb collagen, maintain cell elasticity, promote the regeneration of damaged tissue, improve the skin's repair ability, and delay cell aging, thereby achieving the purpose of maintaining skin elasticity and improving the skin's anti-aging ability; it can also effectively improve the skin's antibacterial properties and reduce skin sensitivity.
[0040] Understandably, vitamin C's antioxidant properties inhibit melanin transfer, while sanguinea seed oil effectively promotes cell renewal, and the Candida mellifera / glucose / rapeseed methyl ester fermentation product promotes collagen absorption. The combination of vitamin C, sanguinea seed oil, and the Candida mellifera / glucose / rapeseed methyl ester fermentation product addresses the root cause, inhibiting melanin transfer. The resulting melanin is then excreted through the skin's own metabolic processes, achieving a synergistic whitening effect. Furthermore, each ingredient is non-photosensitive, stable, completely gentle, and non-irritating.
[0041] In addition, the composition with whitening effect will not cause skin tolerance and rebound, and can still have a good whitening effect after long-term use.
[0042] In some embodiments, the mass ratio of vitamin C, malaria seed oil and Candida albiflora / glucose / rapeseed methyl ester fermentation product is (0.1-5):(0.1-5):(0.05-3); for example, it can be (0.5-4.5):(0.5-4.5):(0.1-2.5), (1-5):(1-5):(0.5-3), (1-4):(1-4):(1-2), (1.5-3.5):(1.5-3.5):(1.5-2.5), (2-3):(2-3):(2-2.5 ), (2.5-3):(2.5-3):(1.5-2), (1.5-5):(1.5-5):(0.5-2.5), (2-5):(2-5):(0.5-2), (2.5-5):(2.5-5):(0.5-1.5), (3-5):(3-5):(0.5-1), (3.5-5):(3.5-5):(0.5-1), (4-5):(4-5):(0.5-1) or (4.5-5):(4.5-5):(0.5-1), etc., are not specifically limited. When the mass ratio of vitamin C, sandalwood seed oil and Candida albicans / glucose / rapeseed methyl ester fermentation product is within the above range, the three ingredients synergistically enhance the effect, inhibit the formation and transfer of melanin from multiple pathways, achieve better whitening effect, and have a good skin feel.
[0043] The second aspect of the present invention provides use of the composition with whitening effect of the first aspect in the preparation of a skin care product with whitening effect.
[0044] The whitening composition is used in skin care products with whitening effects, which has a synergistic whitening effect and improves the whitening effect; the skin care products are not photosensitivity, have good stability, are completely mild and non-irritating.
[0045] A third aspect of the present invention provides a cosmetic with a whitening effect, wherein the active ingredient of the cosmetic comprises the composition with a whitening effect of the first aspect. The cosmetic includes skin care / makeup products such as essence oils, creams, lotions, facial masks, and eye creams.
[0046] The cosmetics address the root cause of the problem through a combination of vitamin C, safflower seed oil, and a fermentation product of Candida albicans, glucose, and rapeseed oil methyl ester. This inhibits melanin transfer and then relies on the skin's own metabolic processes to excrete any melanin produced, achieving a synergistic whitening effect. Furthermore, these ingredients are non-photosensitive and highly stable, preventing skin intolerance and rebound effects, ensuring a strong whitening effect even after prolonged use.
[0047] In some possible implementations, the cosmetics with whitening effect further include a moisturizer to achieve a moisturizing effect on the skin.
[0048] In some embodiments, the moisturizer includes one or more of chitosan, glycerin, butylene glycol, propylene glycol, 1,2-pentanediol, phytosterols, dipropylene glycol, hexylene glycol, polyethylene glycol, panthenol, xylitol, sodium hyaluronate, glycerol polyether, and methyl glucitol polyether.
[0049] As a possible embodiment, the moisturizing agent includes chitosan, sodium hyaluronate and 1,2-pentanediol in a mass ratio of (0.1-2): (0.1-0.3): (0.1-1.5). For example, the mass ratio of chitosan, sodium hyaluronate and 1,2-pentanediol can be (0.2-2): (0.1-0.3): (0.1-1.4), (0.4-2): (0.1-0.3): (0.1-1.2), (0.5-2): (0.1-0.3): (0.1-1), (0.8-2): (0.1-0.3): (0.1-0.8), (1-2): (0.1-0.3): (0.2-0.8) or (1.2-1.8): (0.1-0.3): (0.3-0.8), etc., and is not specifically limited. When the mass ratio of chitosan, sodium hyaluronate and 1,2-pentanediol is within the above range, a better moisturizing effect can be achieved.
[0050] In some embodiments, the cosmetic with whitening effect further comprises a thickener to increase the viscosity of the cosmetic.
[0051] In some embodiments, the thickening agent includes one or more of carbomer, xanthan gum, gum arabic, polymer EMT-10, sodium acrylate / sodium acryloyldimethyltaurate, hydroxyethyl cellulose, and agarose.
[0052] In some embodiments thereof, the thickener includes carbomer and xanthan gum in a mass ratio of (0.1-0.15):(0.1-0.5); for example, the mass ratio of carbomer and xanthan gum can be (0.11-0.15):(0.15-0.5), (0.12-0.15):(0.2-0.5), (0.13-0.15):(0.25-0.5), (0.13-0.15):(0.3-0.45) or (0.13-0.15):(0.3-0.4), etc., specifically not limited. When the mass ratio of carbomer and xanthan gum is within the above range, the cosmetic can have a suitable viscosity.
[0053] In some embodiments, the cosmetics with whitening effects further include an emulsifier, which can improve the bulk stability of the cosmetics to prevent water-oil separation.
[0054] Optionally, the emulsifier includes one or more of glyceryl stearate, PEG-100 stearate, PEG-400 dilaurate, PEG-400 monolaurate, PEG-12 lauryl ether, PEG-20 sorbitan monostearate and cetearyl glucoside; further optionally, the emulsifier includes glyceryl stearate.
[0055] In some embodiments, the cosmetics with whitening effects also include preservatives to reduce corrosion and deterioration of the cosmetics and extend the shelf life of the cosmetics.
[0056] In some embodiments thereof, the preservative includes one or more of phenoxyethanol, methylparaben, propylparaben, imidazolidinyl urea, and DMDM hydantoin.
[0057] In some of these embodiments, the preservative includes phenoxyethanol.
[0058] As a possible implementation method, the cosmetics with whitening effects also include a skin conditioner; the skin conditioner includes dipotassium glycyrrhizate; dipotassium glycyrrhizate has anti-inflammatory, soothing, and anti-free radical oxidation effects, thereby improving the antioxidant, anti-inflammatory, and soothing effects of the cosmetics.
[0059] In some embodiments, the cosmetics with whitening effect include the following components, measured in percentage by mass: 0.1%-5% vitamin C, 0.1%-5% sea sandalwood seed oil, 0.05%-3% of Candida albiflora / glucose / rapeseed oleate fermentation product, 0.1%-2% chitosan, 0.1%-0.3% sodium hyaluronate, 0.1%-0.15% carbomer, 0.1%-1.5% 1,2-pentanediol, 0.1%-0.3% phenoxyethanol, 1%-3% glyceryl stearate, 0.1%-0.5% dipotassium glycyrrhizate, 0.1%-0.5% xanthan gum, and the balance is deionized water.
[0060] The mass percentage of vitamin C in the cosmetic is 0.1%-5%; for example, it can be 0.1%, 0.5%, 1%, 2%, 3%, 4%, 5% or a range between any two of the above values.
[0061] The mass percentage of sea sandalwood seed oil in cosmetics is 0.1%-5%; for example, it can be 0.1%, 0.5%, 1%, 2%, 3%, 4%, 5% or a range between any two of the above values.
[0062] The mass percentage of the fermentation product of Candida albiflora / glucose / rapeseed methyl ester in the cosmetic is 0.05%-3%; for example, it can be 0.05%, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3% or a range between any two of the above values.
[0063] The mass percentage of chitosan in the cosmetic is 0.1%-2%; for example, it can be 0.1%, 0.3%, 0.5%, 0.7%, 1%, 1.3%, 1.5%, 1.7%, 2% or a range between any two of the above values.
[0064] The mass percentage of sodium hyaluronate in the cosmetic is 0.1%-0.3%; for example, it can be 0.1%, 0.15%, 0.2%, 0.25%, 0.3% or a range between any two of the above values.
[0065] The mass percentage of carbomer in the cosmetic is 0.1%-0.15%; for example, it can be 0.1%, 0.11%, 0.12%, 0.13%, 0.14%, 0.15% or a range between any two of the above values.
[0066] The mass percentage of 1,2-pentanediol in the cosmetic is 0.1%-1.5%; for example, it can be 0.1%, 0.3%, 0.5%, 0.8%, 1%, 1.2%, 1.5% or a range between any two of the above values.
[0067] The mass percentage of phenoxyethanol in the cosmetic is 0.1%-0.3%; for example, it can be 0.1%, 0.12%, 0.15%, 0.18%, 0.2%, 0.23%, 0.25%, 0.27%, 0.3% or a range between any two of the above values.
[0068] The mass percentage of glyceryl stearate in the cosmetic is 1%-3%; for example, it can be 1%, 1.5%, 2%, 2.5%, 3% or a range between any two of the above values.
[0069] The mass percentage of dipotassium glycyrrhizate in the cosmetic is 0.1%-0.5%; for example, it can be 0.1%, 0.2%, 0.3%, 0.4%, 0.5% or a range between any two of the above values.
[0070] The mass percentage of xanthan gum in the cosmetic is 0.1%-0.5%; for example, it can be 0.1%, 0.2%, 0.3%, 0.4%, 0.5% or a range between any two of the above values.
[0071] As a possible embodiment, the present invention includes the following components, calculated by mass percentage: 5% vitamin C, 5% sea sandalwood seed oil, 1% Candida albiflora / glucose / rapeseed oleate fermentation product, 1.5% chitosan, 0.2% sodium hyaluronate, 0.14% carbomer, 0.5% 1,2-pentanediol, 0.25% phenoxyethanol, 2.5% glyceryl stearate, 0.35% dipotassium glycyrrhizate, 0.35% xanthan gum, and the balance is deionized water.
[0072] As a possible embodiment, the preparation method of the cosmetic having whitening effect comprises the following steps:
[0073] After mixing the moisturizer, emulsifier, thickener, preservative, dipotassium glycyrrhizate and water, heating to 75-80° C. while stirring and maintaining for 3-5 minutes to prepare a mixture;
[0074] After cooling the mixture to 40-45° C., vitamin C, safflower seed oil, and fermentation product of Candida albicans / glucose / rapeseed oleic acid methyl ester are added to prepare a cosmetic with whitening effect.
[0075] The technical solution of the present invention is described below through specific embodiments.
[0076] 1. Formula composition
[0077] The formulations of the various embodiments and comparative examples are shown in Table 1.
[0078] Table 1
[0079]
[0080]
[0081] The raw materials used in the above examples and comparative examples are all commercially available, among which the fermentation product of Candida albicans / glucose / rapeseed oleic acid methyl ester was purchased from Beijing Lingbao Technology Co., Ltd. with product model P0121130.
[0082] 2. Preparation process
[0083] The preparation methods of Examples 1-3 are as follows:
[0084] Combine sodium hyaluronate, coconut oil, 1,2-pentanediol, phenoxyethanol, chitosan, carbomer, dipotassium glycyrrhizate, glyceryl stearate, xanthan gum, and water in a mixing container, mix thoroughly, stir evenly, and heat while stirring, gradually raising the temperature to 80°C for 5 minutes.
[0085] After the temperature of the mixture container is lowered to 45° C., vitamin C, santobe seed oil, and a fermentation product of Candida albicans / glucose / rapeseed oleic acid methyl ester are added and stirred evenly to obtain an essential oil.
[0086] Comparative Examples 1-6
[0087] The preparation methods of the essential oils in Comparative Examples 1-6 are the same as those in Example 1, except that different amounts of at least one of vitamin C, maltodextrin seed oil, and Candida albicans / glucose / rapeseed oleic acid methyl ester fermentation product are added during the preparation.
[0088] Comparative Example 7
[0089] The preparation method of the essential oil in Comparative Example 7 is as follows:
[0090] Sodium hyaluronate, coconut oil, 1,2-pentanediol, phenoxyethanol, chitosan, carbomer, dipotassium glycyrrhizate, glyceryl stearate, xanthan gum and water are mixed into a stirring container, mixed thoroughly and stirred evenly, and heated while stirring, gradually raising the temperature to 80°C for 5 minutes.
[0091] 3. Performance Testing
[0092] Test samples: Examples 1-3 and Comparative Examples 1-7
[0093] Test subjects: 110 healthy Chinese women with sensitive skin, aged 25-50 years (mean age 39.00 ± 5.83 years), were randomly divided into 11 groups of 10 participants each. All participants provided informed written consent. The participants were willing to cooperate and understand the necessity and duration of the control, adhering to the protocol established by the clinical trial center. Ten groups of subjects were used to test the essential oils of Examples 1-3 and Comparative Examples 1-7, respectively; one group served as a blank control group and did not use any skincare products with whitening properties during the test period.
[0094] Testing Method: Participants in each Example and Comparative Example group applied the essence oil once daily, morning and evening, for 28 consecutive days. Skin gloss was measured using a Glossymeter GL200 on Days 0, 14, and 28. Data were analyzed using SPSS 28.0. Normal distribution was tested. If the data were normally distributed, a T-test was used for statistical analysis; if the data were non-normally distributed, a rank-sum test was used for statistical analysis. Rank-sum data were analyzed using a rank-sum test. A significance level of p < 0.05 was used for statistical analysis.
[0095] Skin color was also measured using a CHROMA METER CR-400 on D0, D14, and D28. A higher L* value indicates brighter skin color; a lower b* value indicates improved skin yellowing; and a higher ITA° value indicates lighter skin color.
[0096] In addition, the experimenter recorded the subjects' skin reactions at D0, D14, and D28, and recorded the results according to the skin reaction grading standards in the "Cosmetic Safety Technical Regulations 2015". The skin reaction grading standards are as follows:
[0097] Grade 0: negative reaction;
[0098] Grade 1: Suspicious reaction; only slight erythema;
[0099] Grade 2: weak positive reaction (erythema reaction); erythema, infiltration, edema, and papules may be present;
[0100] Grade 3: Strong positive reaction (herpes reaction); erythema, infiltration, edema, papules, herpes; the reaction may extend beyond the tested area;
[0101] Grade 4: Very strong reaction (confluent herpes reaction); obvious erythema, severe infiltration, edema, confluent herpes, and the reaction exceeds the test area.
[0102] 1. The skin color test results are shown in Table 2.
[0103] Table 2. Change rate of D28 compared with D0
[0104] Group L* value b* value ITA° value Example 1 +1.09% -38.65% +2.32% Example 2 +0.92% -30.15% +1.92% Example 3 +0.86% -26.59% +1.84% Comparative Example 1 +0.78% -21.12% +1.58% Comparative Example 2 +0.73% -21.20% +1.55% Comparative Example 3 +0.64% -21.16% +1.51% Comparative Example 4 +0.59% -18.61% +1.25% Comparative Example 5 +0.55% -18.49% +1.26% Comparative Example 6 +0.58% -18.69% +1.30% Comparative Example 7 +0.29% -13.65% +1.02% Blank control group +0.18% -10.63% +0.81%
[0105] After 14 days of use of the essential oil in Example 1, the subjects in the Example 1 group experienced a 1.05% increase in L* value, a 7.44% decrease in b* value, and a 1.95% increase in ITA° value. After 28 days of use, the subjects experienced a 1.09% increase in L* value, a 38.65% decrease in b* value, and a 2.32% increase in ITA° value. This demonstrates that the whitening essential oil of the present invention can effectively enhance skin brightness, improve skin yellowing, and whiten skin, thereby effectively improving skin color.
[0106] 2. The skin glossiness test results are shown in Table 3.
[0107] Table 3 Change rate of D28 compared with D0
[0108]
[0109]
[0110] After 14 days of use of the Example 1 essence oil, the subjects' skin glossiness increased by 6.12%. After 28 days of use, the skin glossiness (GU) increased by 8.99%. This demonstrates that the whitening essence oil of the present invention can effectively improve skin gloss. As shown above, after 14 and 28 days of use, the subjects' facial skin color L* and ITA° values significantly increased, their skin color b* values significantly decreased, and their skin glossiness (GU) also significantly improved. This demonstrates that the whitening essence oil of the present invention can effectively brighten skin color, improve skin yellowing, whiten skin, and increase skin gloss, thereby achieving effective whitening efficacy.
[0111] 3. The safety test results are shown in Table 4.
[0112] Table 4
[0113]
[0114]
[0115] As shown in Table 4, the test subjects in the embodiment, comparative example and blank control group scored 0 on both 14D and 28D, indicating that no adverse skin reactions occurred. This indicates that the whitening essential oil of the present invention is safe and non-irritating to the skin.
[0116] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0117] The above-described embodiments merely illustrate several implementations of the present invention, and while their descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent. It should be noted that a person skilled in the art would be able to make numerous variations and improvements without departing from the spirit of the present invention, all of which fall within the scope of protection of the present invention. Therefore, the scope of protection of the patent for this invention shall be determined by the appended claims.
Claims
1. A composition having a whitening effect, characterized in that: The invention comprises vitamin C, maltose seed oil and a fermentation product of Candida albiflora / glucose / rapeseed oleic acid methyl ester; the mass ratio of the vitamin C, the maltose seed oil and the fermentation product of Candida albiflora / glucose / rapeseed oleic acid methyl ester is (0.1-5):(0.1-5):(0.05-3); the fermentation product of Candida albiflora / glucose / rapeseed oleic acid methyl ester is purchased from Beijing Lingbao Technology Co., Ltd.
2. Use of the composition with whitening effect as claimed in claim 1 in the preparation of skin care products with whitening effect.
3. A cosmetic with whitening effect, characterized in that: The active ingredient of the cosmetic comprises the composition with whitening effect as claimed in claim 1.
4. The cosmetic with whitening effect according to claim 3, characterized in that: Also includes moisturizer.
5. The cosmetic with whitening effect according to claim 4, characterized in that: The moisturizing agent includes one or more of chitosan, glycerin, butylene glycol, propylene glycol, 1,2-pentanediol, phytosterol, dipropylene glycol, hexylene glycol, polyethylene glycol, panthenol, xylitol, sodium hyaluronate, glycerol polyether and methyl glucitol polyether.
6. The cosmetic with whitening effect according to claim 5, characterized in that: The moisturizing agent comprises chitosan, sodium hyaluronate and 1,2-pentanediol in a mass ratio of (0.1-2):(0.1-0.3):(0.1-1.5).
7. The cosmetic with whitening effect according to claim 3, characterized in that: Also included are thickeners.
8. The cosmetic with whitening effect according to claim 7, characterized in that: The thickener includes one or more of carbomer, xanthan gum, gum arabic, polymer EMT-10, sodium acrylate / sodium acryloyldimethyltaurate, hydroxyethyl cellulose and agarose.
9. The cosmetic with whitening effect according to claim 8, characterized in that: The thickener comprises carbomer and xanthan gum in a mass ratio of (0.1-0.15):(0.1-0.5).
10. The cosmetic with whitening effect according to claim 3, characterized in that: Also included are emulsifiers.
11. The cosmetic with whitening effect according to claim 10, characterized in that: The emulsifier includes one or more of glyceryl stearate, PEG-100 stearate, PEG-400 dilaurate, PEG-400 monolaurate, PEG-12 lauryl ether, PEG-20 sorbitan monostearate and cetearyl glucoside.
12. The cosmetic with whitening effect according to claim 11, characterized in that: The emulsifier includes glyceryl stearate.
13. The cosmetic with whitening effect according to claim 3, characterized in that: Also includes preservatives.
14. The cosmetic with whitening effect according to claim 13, characterized in that: The preservatives include one or more of phenoxyethanol, methylparaben, propylparaben, imidazolidinyl urea and DMDM hydantoin.
15. The cosmetic with whitening effect according to claim 14, characterized in that: The preservatives include phenoxyethanol.
16. The cosmetic with whitening effect according to any one of claims 3 to 15, characterized in that: Also included are skin conditioning agents.
17. The cosmetic with whitening effect according to claim 16, characterized in that: The skin conditioning agent includes dipotassium glycyrrhizate.
18. The cosmetic with whitening effect according to any one of claims 3 to 15, characterized in that: In terms of mass percentage, it includes the following components: 0.1%-5% vitamin C, 0.1%-5% maltodextrin seed oil, 0.05%-3% Candida albiflora / glucose / methyl rapeseed oil fermentation product, 0.1%-2% chitosan, 0.1%-0.3% sodium hyaluronate, 0.1%-0.15% carbomer, 0.1%-1.5% 1,2-pentanediol, 0.1%-0.3% phenoxyethanol, 1%-3% glyceryl stearate, 0.1%-0.5% dipotassium glycyrrhizate, 0.1%-0.5% xanthan gum, and the balance is deionized water.
Citation Information
Patent Citations
Sunscreen composition, sunscreen product and preparation method and application thereof
CN109394588A
Natural vegetable fat compound formed by imitating human sebum lipid, and preparation method and application of natural vegetable fat compound
CN113876633A