A herbicidal composition and its application

Abstract

The present invention belongs to the field of pesticides, and particularly relates to a herbicidal composition and its application. The herbicidal composition comprises an effective herbicidal amount of active ingredient A and active ingredient B. Among them, active ingredient A is, and active ingredient B is selected from one or more of the following compounds: haloxyfop-P-methyl, cyhalofop-butyl, imazapyr. This composition can effectively control weeds such as Spartina alterniflora, and has the characteristics of expanding the herbicidal spectrum, reducing the application amount, being able to produce a synergistic effect and solving resistant weeds, etc.

Description

Technical Field

[0001] The present invention belongs to the field of pesticides, and particularly relates to a herbicidal composition and its application. Background Art

[0002] Chemical weeding is the most economical and effective means for controlling farmland weeds. However, long-term continuous high-dose use of a single variety or a single mode of action of chemical herbicides easily causes problems such as weed drug resistance and resistance evolution. The reasonable compounding or mixing of herbicide compounds has the advantages of expanding the weed spectrum, improving the control effect, delaying the occurrence and development of weed drug resistance and resistance, etc., and is one of the most effective methods to solve the above problems. There is still a need in production to develop herbicidal composition varieties with high safety, broad herbicidal spectrum, capable of producing synergistic effects and solving the problem of resistant weeds. Summary of the Invention

[0003] To solve the above problems existing in the prior art, the present invention provides a herbicidal composition and its application. The composition can effectively control weeds such as Spartina alterniflora, and has the characteristics of expanding the herbicidal spectrum, reducing the application amount, being able to produce synergistic effects and solving resistant weeds.

[0004] A herbicidal composition comprising an effective herbicidal amount of active ingredient A and active ingredient B, wherein,

[0005] Active ingredient A is

[0006] Active ingredient B is selected from one or more of the following compounds: haloxyfop-P-methyl (CAS: 72619-32-0), cyhalofop-butyl (CAS: 122008-85-9), imazapic (81334-34-1).

[0007] Wherein, the weight ratio of A to B in the herbicidal composition is 1:200 to 200:1, 1:180 to 100:1, 1:160 to 50:1, 1:150 to 30:1, 1:100 to 15:1, 1:80 to 10:1, 1:60 to 5:1, 1:50 to 1:1, 1:30 to 1:5 or 1:15 to 1:10.

[0008] The mass percentage content of A and B in the herbicidal composition accounts for 1-95% of the total amount, preferably 10-80%.

[0009] The herbicidal composition further comprises conventional auxiliaries, and the conventional auxiliaries include carriers and / or surfactants.

[0010] The term "carrier" in this text refers to an organic or inorganic, natural or synthetic substance. They assist in the application of the active ingredient, and this carrier is generally inert and must be agriculturally acceptable, especially acceptable to the plants to be treated. The carrier can be solid, such as clay, natural or synthetic silicates, silica, resins, waxes, solid fertilizers, etc.; or liquid, such as water, alcohols, ketones, petroleum fractions, aromatic or paraffinic hydrocarbons, chlorinated hydrocarbons, liquefied gases, etc.

[0011] Surfactants can include emulsifiers, dispersants or wetting agents, and they can be ionic or non-ionic. Examples that can be mentioned are salts of polyacrylic acid, lignosulfonates, salts of phenol sulfonic acid or naphthalene sulfonic acid, polymers of ethylene oxide with aliphatic alcohols or with aliphatic acids or with aliphatic amines and substituted phenols (especially alkylphenols or arylphenols), sulfosuccinates, taurine derivatives (especially alkyl taurates) and phosphates of alcohols or phosphates of polyhydroxyethylated phenols, alkyl sulfonates, alkyl aryl sulfonates, alkyl sulfates, lauryl ether sulfates, fatty alcohol sulfates, and sulfated cetyl-, heptadecyl- and octadecyl alcohols and sulfated fatty alcohol ethylene glycol ethers. In addition, there are also condensates of naphthalene or naphthalene sulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenyl ether, ethoxylated isooctylphenol, octylphenol or nonylphenol, alkylphenyl polyethylene glycol ethers, tributylphenyl polyethylene glycol ethers, tristearylphenyl polyethylene glycol ethers, alkylaryl polyether alcohols, alcohols and fatty alcohol / ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyethylene glycol ether acetal, sorbitan esters, lignosulfite waste liquor, and proteins, denatured proteins, polysaccharides (such as methylcellulose), hydrophobically modified starches, polyvinyl alcohol, polycarboxylates, polyalkoxylates, polyvinylamine, polyvinylpyrrolidone and their copolymers. At least one surfactant is required to be present to facilitate the dispersion of the active ingredient in water and to enable them to be properly applied to plants.

[0012] The above compositions can also contain various other components, such as protective colloids, binders, thickeners, thixotropic agents, penetrants, stabilizers, chelating agents, dyes, colorants and polymers.

[0013] The herbicidal composition further includes at least one safener, preferably one or more of isoxadifen-ethyl (CAS: 163520-33-0), cyprosulfamide (CAS: 221667-31-8), pyraclonil (CAS: 135590-91-9), cloquintocet-mexyl (CAS: 99607-70-2), gibberellic acid (CAS: 7-06-5), furilazole (CAS: 121776-33-8), metcamifen (CAS: 129531-12-0).

[0014] The composition of the present invention can be diluted by the user before use or used directly. Its formulation can be prepared by conventional processing methods, that is, after mixing the active substance with a liquid solvent or a solid carrier, one or several of surfactants such as dispersants, stabilizers, wetting agents, binders, defoamers, etc. are added.

[0015] The specific formulations of the herbicidal composition are dispersible oil suspensions, aqueous suspensions, suspoemulsions, wettable powders, emulsifiable concentrates, water-dispersible granules (dry suspensions), emulsions in water, and microemulsions.

[0016] In short, the composition of the present invention can be mixed with the solid and liquid additives commonly used in the formulations of the prior art. With the change of external conditions, the usage amount of the active ingredient also varies. The external conditions are, for example, temperature, humidity, the nature of the herbicide used, and so on. It can have a large range of variations, for example, between 0.001 and 2.0 kg / ha, or more of the active substance, but preferably between 0.1 and 1 kg / ha, especially between 1 and 500 g / ha.

[0017] In the context of this specification, if an abbreviated form of the common name of an active compound is used, it includes in each case all the conventional derivatives, such as esters and salts, as well as isomers, especially optical isomers, especially one or more commercially available forms. If the common name represents an ester or a salt, it also includes in each case all other conventional derivatives, such as other esters and salts, free acids and neutral compounds, as well as isomers, especially optical isomers, especially one or more commercially available forms. The chemical names of the compounds given represent at least one compound covered by the common name, usually the preferred compound. In the case of sulfonamides such as sulfonylureas, salts also include the salts formed by the exchange of a cation for a hydrogen atom in the sulfonamide group. For example, the 2-methyl-4-chlorophenoxyacetic acid derivatives include but are not limited to: sodium 2-methyl-4-chlorophenoxyacetate, potassium 2-methyl-4-chlorophenoxyacetate, dimethylammonium 2-methyl-4-chlorophenoxyacetate, isopropylammonium 2-methyl-4-chlorophenoxyacetate, etc., and methyl 2-methyl-4-chlorophenoxyacetate, ethyl 2-methyl-4-chlorophenoxyacetate, isooctyl 2-methyl-4-chlorophenoxyacetate, ethylthioester 2-methyl-4-chlorophenoxyacetate, etc.; the 2,4-D derivatives include but are not limited to: 2,4-D salts such as sodium salt, potassium salt, dimethylammonium salt, triethanolammonium salt, isopropylammonium salt, choline, etc., and 2,4-D esters such as methyl ester, ethyl ester, butyl ester, isooctyl ester, etc.

[0018] The present invention also provides an application of the herbicidal composition in controlling weeds; and provides a method for controlling the growth of unwanted plants, which includes applying the herbicidal composition to plants, plant parts, plant seeds, or the areas where plants grow.

[0019] In addition, the composition of the present invention can be applied to the leaves of the plants to be treated by spraying, that is, applied to weeds, especially the surfaces affected by or prone to be affected by weed infestation.

[0020] When the herbicidal composition of the present invention is applied, an unexpected synergistic effect is obtained, and the herbicidal activity is more significant than the expected sum of the activities of using individual herbicides and the activities of individual herbicides. The synergistic effect is manifested as a reduction in application rate, a wider weed control spectrum, a faster and more persistent herbicidal action, and these characteristics are required in the process of weed control practice. In terms of the described characteristics, these new compositions are significantly superior to existing herbicides, achieving reduced use and being more environmentally friendly.

[0021] The synergistic herbicidal composition of the present invention also has the following advantages:

[0022] (1) The composition of the present invention is environmentally friendly and is easily degradable in the environment.

[0023] (2) The herbicidal composition of the present invention has a low cost and is convenient to use, and its popularization and application have great economic and social benefits.

[0024] All patents, patent applications, and publications mentioned or cited herein are incorporated herein by reference in their entirety to the same extent as if each was individually cited. Detailed Description of the Invention

[0025] The following examples are not intended to limit the present invention, but are only used to illustrate how the present invention is implemented. For certain weeds, these examples show particularly significant effectiveness. Examples are as follows:

[0026] A) Examples

[0027] 1. A + Haloxyfop-P-methyl (4 + 4) EC

[0028] 4%A + 4% Haloxyfop-P-methyl + 5% Calcium dodecylbenzenesulfonate + 7% Cardanol polyoxyethylene ether + 5% N-Octylpyrrolidone + 10% Solvent oil 180# + Made up with methyl esters of fatty acids

[0029] 2. A + Cyhalofop-butyl (4 + 25) EC

[0030] 4%A + 25% Cyhalofop-butyl + 5% Calcium dodecylbenzenesulfonate + 5% Cardanol polyoxyethylene ether + 2% Block polyether emulsifier + 5% Organosilicon wetting and penetrating agent + 5% N-Octylpyrrolidone + Made up with solvent oil 180#

[0031] 3. A + Imazapyr (4 + 75) WP

[0032] 4%A + 75% Imazapyr + 3% Fumed silica + 3% Sodium dodecyl sulfate + 3% Polycarboxylate dispersant + 2% Sodium lignosulfonate + Made up with diatomite

[0033] Processing equipment for the above EC: Vacuum pump, batching kettle, storage tank.

[0034] The processing procedure of the above-mentioned emulsifiable concentrate: Put all the materials into the batching kettle, stir and dissolve until it becomes completely transparent. After passing the inspection by chemical analysis, transfer it to the storage tank for filling.

[0035] The above-mentioned wettable powder processing equipment: mechanical pulverizer, air-flow pulverizer.

[0036] The processing procedure of the above-mentioned wettable powder: Put all the materials such as the technical material and additives into the mechanical pulverizer, then pass it through the air-flow pulverizer. After passing the inspection by sampling and chemical analysis, it is reserved for use.

[0037] B) Efficacy test

[0038] Post-emergence foliar spray treatment:

[0039] 1) Test conditions

[0040] 1.1), Test targets

[0041] The weeds are cultivated by the pot method. Use 180х140mm plastic nutrient pots, place them in enamel trays, which are filled with the surface soil (at the 4 / 5 position) collected from the farmland, air-dried and sieved. The soil humidity is initially controlled at 20%. Select the plump and uniform weed seeds, soak them in warm water at 25°C for 6 hours, germinate them in a biochemical incubator at 28°C (in the dark). Evenly place the weed seeds that have just shown white tips on the soil surface, and then cover the soil with 0.5 - 1 cm according to the particle size of the seeds.

[0042] 1.2), Cultivation conditions

[0043] It is carried out in a controllable sunlight greenhouse, with the temperature of 20 - 30°C, natural light, and the relative humidity of 57% - 72%. The soil type is loam, the organic matter content is 1.63%, pH = 7.1, the available nitrogen is 84.3mg / kg, the available phosphorus is 38.5mg / kg, and the available potassium is 82.1mg / kg.

[0044] 1.3), Instrument and equipment

[0045] 3WP-2000 type walking spray tower, Nanjing Institute of Agricultural Machinery, Ministry of Agriculture. GA0 type ten-thousandth electronic balance (Germany); ZDR2000 intelligent data recorder (Hangzhou Zeda Instrument Co., Ltd.); SPX type intelligent biochemical incubator (Ningbo Jiangnan Instrument Factory).

[0046] 2) Test design

[0047] 2.1), Reagents

[0048] The required active ingredients are purchased from reagent companies or prepared by conventional methods. The technical materials all use acetone as the solvent and are diluted with an aqueous solution of 0.1% emulsifier Tween-80, and are diluted immediately before use.

[0049] 2.2), Test Treatments

[0050] 2.2.1), Dosage Setting

[0051] When determining the ratio or content of A and active ingredient B, it should be measured from the action characteristics and toxicity of the two agents, and the main purpose of using the formulation should also be considered. Based on the preliminary pre-tests in this study, the single and mixed dosages of active ingredients A and B are shown in the table respectively. Water containing no agent, the same solvent and emulsifier is used as the blank control.

[0052] 2.2.2), Test Replication

[0053] Each treatment is replicated 4 times. For each replication, 3 pots are used, and 20 weed seeds are sown in each pot. There are a total of 60 plants for each treatment.

[0054] 2.3), Treatment Method

[0055] 2.3.1), Treatment Time and Frequency

[0056] The test is carried out with the medicine used once. When the weeds are at the 1.5 - 2 leaf stage, thin out the seedlings to keep 10 weeds in each pot, and 30 plants are retained for each treatment. Then continue to cultivate until the 4 - 5 leaf stage for treatment.

[0057] 2.3.2), Application Equipment and Application Method

[0058] Place the cultivated test materials evenly on a platform with an area of 0.5 m 2 , and spray the stems and leaves with a 3WP - 2000 type walking spray tower. The spray liquid volume is calculated at 450 kg / ha, and the spray pressure is 0.3 MPa. After all the liquid medicine is sprayed, close the air valve. After 30 seconds, open the spray tower door and take out the nutrient pots. Then open the air valve and spray 50 mL of clear water to clean the spray liquid pipe.

[0059] 3) Test Method

[0060] The pot - culture method is adopted. Weed cultivation is as described in 1.1), and it is carried out with reference to "Pesticide Bioassay Guidelines for Indoor Herbicides". The application method is as described in 2.3.2), and the stem - leaf treatment method is adopted. After treatment, transfer them to the greenhouse for conventional cultivation.

[0061] 4) Data Investigation and Statistical Analysis

[0062] 4.1), Investigation Method

[0063] The absolute - number investigation method is adopted. Use a blade to cut the whole seedlings of the surviving weeds along the soil surface, and weigh the fresh weight of the weeds with an analytical balance. For the weeds that have died, count the fresh weight as zero.

[0064] 4.2), Investigation Time and Frequency

[0065] 21-day investigation after treatment, with a total of 1 investigation.

[0066] 4.3), Data statistical analysis

[0067] Use the Gowing method to calculate the theoretical fresh weight inhibition rate (E0 = X + Y - X * Y / 100) of each treatment mixture combination, and then compare it with the measured inhibition rate (E) to evaluate the combined action type of the two mixtures on weeds. When the value of E - E0 is greater than 10% it is a synergistic effect, less than -10% it is an antagonistic effect, and between -10% and 10% it is an additive effect. And determine the optimal ratio according to factors such as the actual control effect, the characteristics of the herbicide, and the balance of the formulation. In the formula, X is the fresh weight inhibition rate when the dosage of active ingredient A is P; Y is the fresh weight inhibition rate when the dosage of active ingredient B is Q.

[0068] The statistical results are shown in Table 1-3 below.

[0069] Table 1 Actual control effect and combined action evaluation of A mixed with haloxyfop-P-methyl on Spartina alterniflora

[0070]

[0071] Table 2 Actual control effect and combined action evaluation of A mixed with cyhalofop-butyl on Spartina alterniflora

[0072]

[0073] Table 3 Actual control effect and combined action evaluation of A mixed with imazapyr on Spartina alterniflora

[0074]

[0075] C) Field demonstration

[0076] Use the herbicidal composition prepared in Examples 1-3 above to conduct a test on the control effect of Spartina alterniflora in coastal tidal flats.

[0077] Test method:

[0078] Foliar treatment (F): When the weeds are in the 5-7 leaf stage, use unmanned aerial vehicle spraying, with a water dilution of 2 kg / 667m 2 , and uniformly spray by foliar spraying.

[0079] The specific test agents and dosages are shown in Table 4. The plot area is 667 square meters, and each treatment is repeated 3 times. The control effect was investigated 15 days after spraying and is shown in Table 4.

[0080]

[0081] Table 4 Field demonstration effect of the compound composition described

[0082] Example Dosage (g a.i. / ha) Control efficacy on fresh weight (%) 1 120 94.2 2 435 90 3 1185 92.1

[0083] Through a large number of experiments and explorations, the present invention unexpectedly discovers that the said composition is used for controlling mainly gramineous weeds, broad-leaved weeds, cyperaceae weeds, etc., and has a surprising and unexpected synergistic effect. In particular, it has a significant synergistic effect on Spartina alterniflora. This synergistic effect is more significant at low doses, can reduce the dosage of pesticides, reduce environmental pollution, and the reasonable compounding reduces the agricultural cost, having a very good application prospect. At the same time, through tests, it shows good selectivity and excellent synergistic effect in plants such as wheat fields, corn fields, rice fields, peanuts, sugarcane, sorghum, millet, potatoes, rape, soybeans, cotton, vegetables, Poa annua, Festuca arundinacea, Zoysia japonica, etc., and can be developed into a herbicide mixture with broad market value.

Claims

1. A herbicidal composition, characterized in that, Comprising a herbicidally effective amount of active ingredient A and active ingredient B, wherein active ingredient A is ; the active ingredient B is selected from one of the following compounds: haloxyfop-P-methyl, cyhalofop-butyl, imazapyr; when B is haloxyfop-P-methyl, the weight ratio of A to B in the herbicidal composition is 1:6 to 8:3; when B is cyhalofop-butyl, the weight ratio of A to B in the herbicidal composition is 1:50 to 8:25; when B is imazapyr, the weight ratio of A to B in the herbicidal composition is 1:150 to 8:

75.

2. The herbicidal composition according to claim 1, characterized in that, when B is haloxyfop-P-methyl, the weight ratio of A to B in the herbicidal composition is 1:5 to 1:1; when B is cyhalofop-butyl, the weight ratio of A to B in the herbicidal composition is 1:30 to 1:5; when B is imazapyr, the weight ratio of A to B in the herbicidal composition is 1:100 to 1:

10.

3. The herbicidal composition according to claim 1, characterized in that, when B is cyhalofop-butyl, the weight ratio of A to B in the herbicidal composition is 1:15 to 1:5; when B is imazapyr, the weight ratio of A to B in the herbicidal composition is 1:50 to 1:

10.

4. The herbicidal composition according to any one of claims 1-3, characterized in that, the mass percentage content of A and B in the herbicidal composition accounts for 1-95% of the total amount.

5. The herbicidal composition according to claim 4, characterized in that, the mass percentage content of A and B in the herbicidal composition accounts for 10-80% of the total amount.

6. The herbicidal composition according to any one of claims 1-3, characterized in that, the herbicidal composition further comprises conventional auxiliaries.

7. The herbicidal composition according to claim 6, characterized in that, the conventional auxiliaries include carriers and / or surfactants.

8. The herbicidal composition according to any one of claims 1-3, characterized in that, the herbicidal composition further comprises at least one safener.

9. The herbicidal composition according to claim 8, characterized in that, the safener is selected from one or more of isoxadifen-ethyl, cyprosulfamide, pyraclonil, cloquintocet-mexyl, gibberellic acid, furilazole or metcamifen.

10. The herbicidal composition according to any one of claims 1-3, characterized in that, the specific formulation of the herbicidal composition is a dispersible oil suspension, a water suspension, a suspension emulsion, a wettable powder, an emulsifiable concentrate, a water dispersible granule, an emulsion in water or a microemulsion.

11. Use of the herbicidal composition according to any one of claims 1 to 10 in controlling weeds.

12. The use according to claim 11, characterized in that, the weeds are Spartina alterniflora.

13. A method for controlling the growth of unwanted plants, which comprises applying the herbicidal composition according to any one of claims 1 to 10 to plants, plant seeds or the areas where plants grow.

14. The method according to claim 13, characterized in that, the unwanted plants are Spartina alterniflora.

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