oxygenator

Abstract

The application provides an oxygenator, comprising a shell and a pre-module arranged in the shell. The pre-module comprises a plurality of pre-units arranged in layers, and each pre-unit comprises three membrane filament layers arranged in layers, and the three membrane filament layers are arranged at an angle of 120 degrees between each other. The three membrane filament layers comprise one first pre-membrane filament layer and two second pre-membrane filament layers, the first pre-membrane filament layer is one of an oxygenation membrane filament layer and a temperature control membrane filament layer, and the second pre-membrane filament layer is the other of the oxygenation membrane filament layer and the temperature control membrane filament layer. In all pre-units, the arrangement angle of the first pre-membrane filament layer is the same. The pre-module forms a uniform blood passage, improves the uniformity of blood distribution, avoids a large pressure drop of blood in the blood passage, thereby reduces thrombosis, and is beneficial to exerting the best oxygenation efficiency of the oxygenator.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to an oxygenator. Background Technology

[0002] An oxygenator is an artificial device that enables blood gas exchange. Currently used oxygenators typically contain an oxygenation unit within a housing, with sidewall channels forming between the oxygenation unit and the housing. The oxygenation unit also has a cylindrical central channel. When blood enters the sidewall channels through the blood inlet, it is distributed along these channels and then flows through the oxygenation unit before converging into the central channel.

[0003] In existing technologies, oxygenators are mainly categorized into cylindrical and cubic shapes. When blood flows in a cylindrical oxygenator, the widths of the central flow channel, sidewall flow channels, and flow channels generated by the oxygenation unit are typically variable, which is detrimental to stabilizing blood flow velocity and prevents the oxygenator from achieving optimal oxygenation efficiency. Conversely, cubic oxygenators have sharp corners, which can easily lead to thrombosis when blood flows through them, posing a safety risk. If cylindrical flow channels are formed within a cubic oxygenator, the cubic shape results in excessive redundant space, leading to a larger overall volume and poor uniformity of oxygen flow within the oxygenator, which is also detrimental to its optimal performance. Summary of the Invention

[0004] In order to overcome the above-mentioned defects of the prior art, the technical problem to be solved by the embodiments of the present invention is to provide an oxygenator for improving the uniformity of blood channels to improve oxygenation efficiency.

[0005] The above-mentioned objective of this invention can be achieved by the following technical solution: This invention provides an oxygenator, comprising:

[0006] The casing has a blood inlet and a blood outlet;

[0007] The pre-approval module, housed within the casing, comprises multiple stacked pre-approval units located between the blood inlet and blood outlet. Each pre-approval unit includes three stacked membrane fiber layers, arranged at 120° intervals between each pair of the three membrane fiber layers. The three membrane fiber layers include: one first pre-approval membrane fiber layer and two second pre-approval membrane fiber layers. The first pre-approval membrane fiber layer is one of an oxygenation membrane fiber layer and a temperature control membrane fiber layer, and the second pre-approval membrane fiber layer is the other of the oxygenation membrane fiber layer and the temperature control membrane fiber layer. In all pre-approval units, the angle of the first pre-approval membrane fiber layer is the same.

[0008] The technical solution of the present invention has the following significant beneficial effects:

[0009] This invention places a pre-module between the blood inlet and the blood outlet, and the pre-module consists of multiple pre-units. The overlapping area of ​​the three stacked membrane fibers of the pre-unit can form a partial blood channel. Thus, through the cooperation of multiple pre-units, a uniform blood channel can be formed between the blood inlet and the blood outlet. Blood flows into the blood channel through the blood inlet, undergoes oxygenation along the blood channel, and finally flows out from the blood outlet.

[0010] This invention, through a pre-module, can form a uniform blood channel, improving the uniformity of blood distribution and avoiding large pressure drops within the blood channel, thereby reducing thrombosis and facilitating optimal oxygenation efficiency of the oxygenator. Furthermore, at least one of the three membrane fiber layers is a temperature-controlled membrane fiber layer, which can regulate the temperature of the blood entering the blood channel, maintaining it within an optimal oxygenation range, thus improving oxygenation efficiency. By arranging the three membrane fiber layers at 120° intervals between each other, it is easy to control the inlet and outlet directions of each membrane fiber layer, allowing the oxygenation medium or temperature-controlled medium to flow more concentratedly into the corresponding membrane fiber layers, improving the structural integration.

[0011] Furthermore, the pre-treatment unit employs a structural design that combines oxygenation membrane fibers and temperature-controlled membrane fibers. This allows blood to be oxygenated and heated simultaneously as it passes through the pre-treatment module, resulting in at least a partial temperature rise as the blood flows downstream. This temperature rise is beneficial for improving oxygenation efficiency. Therefore, in a further preferred embodiment, by placing a post-treatment module containing only oxygenation membrane fibers downstream of the pre-treatment module, the oxygenated blood after the temperature rise can be oxygenated to the maximum extent possible, thereby further improving the blood oxygenation efficiency.

[0012] Furthermore, the three membrane fibers form a unit, and the three membrane fibers in each unit are stacked in a circumferentially evenly distributed manner, arranged in pairs at 120° angles. This method offers other advantages compared to using fewer (2 layers) or more (e.g., 4, 5, 6 layers) membrane fibers to define a single unit. Specifically, to accommodate the flat stacking of the membrane fibers, it is necessary to seal the outer circumference of the stacked membrane fiber layers. After the sealant cures, it is trimmed to form the sealing layer described below. In practice, most modules formed after trimming are cylindrical. Therefore, using a fewer membrane fiber stacking structure results in a larger amount of trimming because the cross-sectional shape of the stacked membrane fiber layer is far from circular. This means that less membrane fiber and sealant are effectively utilized, leading to material waste. Using a higher number of membrane fiber stacking structures can alleviate the above problems. Moreover, the more membrane fiber layers stacked at angles, the higher the effective utilization rate of membrane fibers and sealant. However, the more membrane fiber layers a unit has, the more difficult the membrane fiber stacking process becomes, thus significantly reducing manufacturing efficiency. Practical experience shows that using three layers of membrane fiber can better balance both of these aspects: improving the effective utilization rate of both membrane fiber and sealant without reducing the oxygenator manufacturing efficiency. Attached Figure Description

[0013] Figure 1 This is a cross-sectional view of the oxygenator described in this invention.

[0014] Figure 2 This is a top sectional view of the front module described in this invention.

[0015] Figure 3 This is a top view of one of the front-end units described in this invention;

[0016] Figure 4 This is a top cross-sectional view of the rear unit described in this invention;

[0017] Figure 5 This is a schematic diagram of a three-dimensional mounting structure of the front unit and the rear unit described in this invention;

[0018] Figure 6 This is a top view of one of the partition plates described in this invention.

[0019] Figure 7 This is a three-dimensional structural diagram of the oxygenation medium inlet described in this invention;

[0020] Figure 8 This is a three-dimensional structural diagram of the oxygenation medium outlet described in this invention.

[0021] The reference numerals in the above figures are as follows:

[0022] 1. Shell; 101. First chamber; 102. Second chamber; 103. Third chamber; 104. Fourth chamber; 105. Fifth chamber; 106. Sixth chamber; 11. Blood inlet; 12. Blood outlet; 13. Temperature-controlled medium inlet; 14. Temperature-controlled medium outlet; 15. Oxygenation medium inlet; 16. Oxygenation medium outlet; 17. First end cap; 18. Second end cap;

[0023] 2. Front module; 21. Front unit; 211. First front membrane fiber layer; 212. Second front membrane fiber layer; 22. First sealing layer;

[0024] 3. Rear module; 31. Rear oxygen membrane fiber layer; 32. Second sealing layer;

[0025] 4. Front-mounted partition assembly; 41. First partition; 42. Second partition;

[0026] 5. Rear-mounted partition assembly; 51. Third partition;

[0027] 6. Divider plate; 61. Flow hole. Detailed Implementation

[0028] like Figures 1 to 3 As shown, this embodiment provides an oxygenator, including a housing 1 and a pre-module 2. The housing 1 has a blood inlet 11 and a blood outlet 12. The pre-module 2 is disposed within the housing 1 and includes multiple stacked pre-units 21 located between the blood inlet 11 and the blood outlet 12. Each pre-unit 21 includes three stacked membrane fiber layers, with each pair of membrane fiber layers arranged at 120° intervals. The three membrane fiber layers include: one first pre-membrane fiber layer 211 and two second pre-membrane fiber layers 212. The first pre-membrane fiber layer 211 is one of an oxygenation membrane fiber layer and a temperature control membrane fiber layer, and the second pre-membrane fiber layer 212 is the other of an oxygenation membrane fiber layer and a temperature control membrane fiber layer. In all the pre-units 21, the first pre-membrane fiber layer 211 is arranged at the same angle.

[0029] By placing the pre-module 2 inside the housing 1 between the blood inlet 11 and the blood outlet 12, and the pre-module 2 being composed of multiple pre-units 21, the overlapping area of ​​the three stacked membrane filaments of the pre-unit 21 can form a partial blood channel, thereby forming a uniform blood channel between the blood inlet 11 and the blood outlet 12 through the cooperation of multiple pre-units 21.

[0030] During oxygenation, blood flows into the blood channel through the blood inlet 11 and undergoes oxygenation along the blood channel before finally flowing out from the blood outlet 12. The pre-module 2 forms a uniform blood channel, improving the uniformity of blood distribution and preventing large pressure drops in the blood channel, thereby reducing thrombosis and facilitating the optimal oxygenation efficiency of the oxygenator.

[0031] Furthermore, at least one of the three membrane fiber layers is a temperature-controlled membrane fiber layer. This temperature-controlled membrane fiber layer can regulate the temperature of the blood entering the blood channel, maintaining the blood temperature within an optimal oxygenation range, thereby improving oxygenation efficiency. The pre-unit 21 can centrally arrange the oxygenation membrane fiber layer and the temperature-controlled membrane fiber layer, thereby reducing the volume of the oxygenator and improving its integration. Moreover, by arranging the three membrane fiber layers at 120° intervals between each pair, it is easier to control the inlet and outlet directions of each membrane fiber layer, allowing the oxygenation medium or temperature-controlled medium to flow more concentratedly into the corresponding membrane fiber layer, improving the ease of use of the oxygenator.

[0032] like Figure 4 As shown, the oxygenator also includes a post-module 3, which is located inside the housing 1 between the pre-module 2 and the blood outlet 12. The post-module 3 includes three stacked post-oxygenation membrane filament layers 31, which are arranged at 120° to each other.

[0033] By incorporating a post-module 3, which further forms a partial blood channel through three post-oxygenation membrane filament layers 31, the length of the blood channel is increased. The post-module 3 extends the oxygenation path of the blood within the blood channel, thereby improving the blood oxygenation effect.

[0034] One of the three stacked post-oxygenation membrane fiber layers 31 has the same angle as one of the pre-oxygenation membrane fiber layers. This makes it easier to control the inlet and outlet directions of the pre-oxygenation membrane fiber layer and the post-oxygenation membrane fiber layer 31, so that the oxygenation medium can flow into the pre-oxygenation membrane fiber layer and the post-oxygenation membrane fiber layer 31 at the same time, simplifying the gas path structure inside the oxygenator and improving the integration of the oxygenator.

[0035] Each front unit 21 and rear module 3 can form a roughly cylindrical blood channel. The cylindrical blood channel has a more uniform radial dimension, which improves the uniformity of blood distribution and allows the blood to flow more stably in the oxygenator.

[0036] Multiple post-modules 3 can be set up. The post-oxygenation membrane filaments 31 of multiple post-modules 3 can work together to increase the length of the blood channel, thereby meeting the oxygenation needs of blood with different flow rates.

[0037] like Figure 2 , Figure 4 and Figure 5As shown, a front-mounted sealing assembly 4 is provided between the front module 2 and the housing 1. The front-mounted sealing assembly 4 and the front module 2 define a closed first chamber 101 and a second chamber 102. The two ends of the temperature-controlled membrane fiber layer are respectively connected to the first chamber 101 and the second chamber 102. The housing 1 is also provided with a temperature-controlled medium inlet 13 and a temperature-controlled medium outlet 14. The temperature-controlled medium inlet 13 is connected to one of the first chamber 101 and the second chamber 102, and the temperature-controlled medium outlet 14 is connected to the other of the first chamber 101 and the second chamber 102.

[0038] By utilizing the pre-sealing assembly 4 to form a closed first chamber 101 and a second chamber 102 between the front module 2 and the housing 1, the two ends of the temperature-controlled membrane fiber layer are respectively connected to the first chamber 101 and the second chamber 102. This allows the temperature-controlled medium to flow more concentratedly into and out of the temperature-controlled membrane fiber layer through the first chamber 101 and the second chamber 102, improving the efficiency of the temperature-controlled medium entering and exiting each temperature-controlled membrane fiber layer. Furthermore, the temperature-controlled medium can regulate the blood temperature in the blood channel, maintaining the blood within an optimal oxygenation temperature range, which is beneficial for improving the blood oxygenation efficiency.

[0039] A rear sealing assembly 5 is provided between the rear module 3 and the housing 1. The rear sealing assembly 5 divides the gap space between the rear module 3 and the housing 1 into two symmetrical third chambers 103 and fourth chambers 104. One end of each rear oxygenation membrane fiber layer 31 is connected to the third chamber 103, and the other end of each rear oxygenation membrane fiber layer 31 is connected to the fourth chamber 104.

[0040] By utilizing the post-sealing assembly 5 to form a third chamber 103 and a fourth chamber 104 between the post-module 3 and the housing 1, the two ends of the post-oxygenation membrane fiber layer 31 are respectively connected to the third chamber 103 and the fourth chamber 104. This allows the oxygenation medium to flow more concentratedly into and out of the post-oxygenation membrane fiber layer 31 through the third chamber 103 and the fourth chamber 104, improving the efficiency of the oxygenation medium entering and exiting each post-oxygenation membrane fiber layer 31. Furthermore, blood can further undergo an oxygenation reaction with the oxygenation medium in the post-oxygenation membrane fiber layer 31, thereby increasing the oxygen content in the blood.

[0041] Furthermore, the pre-sealing assembly 4 and the pre-module 2 define a fifth chamber 105 and a sixth chamber 106, with both ends of the pre-oxygenated membrane filament layer communicating with the fifth chamber 105 and the sixth chamber 106, respectively. The fifth chamber 105 and the sixth chamber 106 are open towards the rear module 3; the fifth chamber 105 communicates with the third chamber 103, and the sixth chamber 106 communicates with the fourth chamber 104. The housing 1 also has an oxygenated medium inlet 15 and at least one oxygenated medium outlet 16. The oxygenated medium inlet 15 communicates with the third chamber 103 and / or the fifth chamber 105, and the oxygenated medium outlet 16 communicates with the fourth chamber 104 and / or the sixth chamber 106.

[0042] By utilizing the pre-sealing assembly 4 to form a fifth chamber 105 and a sixth chamber 106 between the pre-module 2 and the housing 1, the two ends of the pre-oxygenation membrane fiber layer are connected to the fifth chamber 105 and the sixth chamber 106 respectively. This allows the oxygenation medium to flow more concentratedly into and out of the pre-oxygenation membrane fiber layer through the fifth chamber 105 and the sixth chamber 106, improving the efficiency of the oxygenation medium entering and exiting each pre-oxygenation membrane fiber layer. Furthermore, blood can undergo an oxygenation reaction with the oxygenation medium in the pre-oxygenation membrane fiber layer, thereby increasing the oxygen content in the blood.

[0043] Multiple pre-oxygenation membrane fibers can perform primary oxygenation of the blood, and multiple post-oxygenation membrane fibers 31 can perform secondary oxygenation of the blood, thereby further replenishing the oxygen content of the blood and achieving a better oxygenation effect.

[0044] Furthermore, the fifth chamber 105 and the sixth chamber 106 are open towards the rear module 3, allowing the fifth chamber 105 to connect with the third chamber 103 and the sixth chamber 106 to connect with the fourth chamber 104. Thus, injecting the oxygenating medium into either the third chamber 103 or the fifth chamber 105 allows the oxygenating medium to flow simultaneously into both the pre-oxygenation membrane fiber layer and the post-oxygenation membrane fiber layer 31, improving the input efficiency of the oxygenating medium. Moreover, the oxygenating medium flowing out of the pre-oxygenation membrane fiber layer can enter the fourth chamber 104, and the oxygenating medium flowing out of the post-oxygenation membrane fiber layer 31 can enter the sixth chamber 106. The oxygenating medium can be output through either the fourth chamber 104 or the sixth chamber 106, thereby improving the discharge efficiency of the oxygenating medium.

[0045] The housing 1 includes a cylindrical body, a first end cap 17 and a second end cap 18 disposed at both ends of the cylindrical body along the axial direction. The front module 2 also includes a first sealing layer 22 formed on the radial outer periphery of the membrane fiber layer.

[0046] The pre-sealing assembly 4 includes four first partitions 41 and two second partitions 42. Each first partition 41 extends axially, and the four first partitions 41 are arranged circumferentially at intervals. Each second partition 42 extends radially, and the two second partitions 42 are arranged circumferentially at intervals. The radially outer end of each first partition 41 is connected to the inner wall of the cylindrical body, and the radially inner end of each first partition 41 is connected to the first sealing layer 22. The radially outer end of each second partition 42 is connected to the inner wall of the cylindrical body, and the radially inner end of each second partition 42 is connected to the first sealing layer 22. One axial end of each first partition 41 is connected to the first end cap 17.

[0047] The four first partitions 41 are arranged in pairs. The other ends of the two first partitions 41 in the first group are connected to one of the second partitions 42 along the axial direction, and the other ends of the two first partitions 41 in the second group are connected to the other second partition 42 along the axial direction. The two first partitions 41 in the first group and the second partitions 42 connected thereto, the first end cap 17, and the cylindrical body define the first chamber 101. The two first partitions 41 in the second group and the second partitions 42 connected thereto, the first end cap 17, and the cylindrical body define the second chamber 102. The two adjacent first partitions 41 in the first group and the first end cap 17 and the cylindrical body connected thereto define the fifth chamber 105 and the sixth chamber 106, respectively.

[0048] As described in the structural design, the temperature-controlled medium is isolated at the temperature-controlled medium inlet chamber (either of the first chamber 101 and the second chamber 102), allowing it to enter only that chamber and subsequently the temperature-controlled membrane filament layer. Both modules within the oxygenator housing—the front module 2 and the rear module 3—contain oxygenation membrane filament layers. Therefore, connecting the inlet ends of the oxygenation membrane filament layers in the two modules allows the oxygenation medium to be supplied to both modules simultaneously. This achieves both isolation between different media (temperature-controlled medium and oxygenation medium), ensuring that only the corresponding membrane filament layer enters, and unified supply and discharge of the same medium. This avoids the need for separate inlets and outlets for the oxygenation membrane filaments in different modules, simplifying the oxygenator structure.

[0049] In one specific embodiment, when the three membrane fiber layers of the front unit 21 are arranged at 120° intervals between each other, a roughly hexagonal overlapping region can be formed between the three membrane fiber layers. The inner wall of the first sealing layer 22 is circumferentially arranged along the direction of the largest inscribed circle of this hexagonal overlapping region, so that the region enclosed by the first sealing layer 22 forms a partial blood channel with the largest cross-sectional area, thus having better blood delivery capacity.

[0050] The first partition 41 is rectangular in shape, with its outer radial end integrally formed with the inner wall of the cylindrical body, and its inner radial end inserted into the first sealing layer 22. Alternatively, the outer radial end of the first partition 41 is connected to the inner wall of the cylindrical body, and its inner radial end abuts against the first sealing layer 22.

[0051] The second partition 42 is partially annular, with its radially outer end integrally formed with the inner wall of the cylindrical body, and its radially inner end inserted into the first sealing layer 22. Alternatively, the radially outer end of the second partition 42 is connected to the inner wall of the cylindrical body, and its radially inner end abuts against the bottom end of the first partition 41 and connects with the first sealing layer 22 to form a seal.

[0052] The first end cap 17 and / or the second end cap 18 are detachably mounted on the housing 1, which allows the front module 2 and the rear module 3 to be quickly installed and fixed inside the housing 1, improving assembly efficiency.

[0053] like Figure 4 As shown, the rear module 3 also includes a second sealing layer 32 formed on the radial outer periphery of the rear oxygenated membrane filament layer 31. The rear sealing assembly 5 includes two third partitions 51, each extending axially, and the two third partitions 51 are arranged circumferentially spaced. The radial outer end of the third partition 51 is in contact with the inner wall of the cylindrical body, and the radial inner end is in contact with the second sealing layer 32. One axial end of the third partition 51 is in contact with the second end cap 18. The other axial end of one of the third partitions 51 is in contact with one of the second partitions 42, and the other axial end of the third partition 51 is in contact with the other second partition 42. One of the third partitions 51 and the connected second partition 42, the second end cap 18, and the cylindrical body define a third chamber 103, and the other third partition 51 and the connected second partition 42, the second end cap 18, and the cylindrical body define a fourth chamber 104.

[0054] Since the rear module 3 only contains oxygenation membrane fibers, the rear sealing assembly 5 is mainly used to divide the included rear oxygenation membrane fiber layer 31 into inlet and outlet sections, thus isolating the oxygenation medium inlet and outlet of the rear oxygenation membrane fiber layer 31 from each other. The rear sealing assembly 5 achieves this purpose through the aforementioned structural design. Furthermore, the two third partitions 51 included in the rear sealing assembly 5, in cooperation with the second partition 42 of the front sealing assembly 4, connect the oxygenation medium inlet chambers of the upper and lower modules, and also connect the oxygenation medium outlet chambers of the upper and lower modules, thereby realizing the unified supply and discharge of oxygenation medium to the front module 2 and the rear module 3 as described above.

[0055] In one specific embodiment, when the three post-oxygenation membrane fiber layers 31 are arranged at 120° intervals between each other, a roughly hexagonal overlapping region can be formed between the three post-oxygenation membrane fiber layers 31. The inner wall of the second sealing layer 32 is circumferentially arranged along the direction of the largest inscribed circle of the hexagonal overlapping region, so that the area sandwiched by the second sealing layer 32 can also form a partial blood channel.

[0056] Preferably, the partial blood channels formed by the first sealing layer 22 and the second sealing layer 32 have the same shape and size, thereby ensuring the uniform distribution of blood in the blood channels, avoiding the formation of blood clots due to pressure drop between the front module 2 and the rear module 3, and improving the safety of use.

[0057] Furthermore, the third partition 51 is rectangular, with its outer radial end integrally formed with the inner wall of the cylindrical body, and its inner radial end inserted into the second sealing layer 32. Alternatively, the outer radial end of the third partition 51 is connected to the inner wall of the cylindrical body, and the inner radial end of the third partition 51 abuts against the second sealing layer 32.

[0058] like Figure 6 As shown, the oxygenator also includes a partition plate 6, which comprises a generally circular main body and multiple flow holes 61 disposed on the main body. The main body is located between the front module 2 and the rear module 3, and the blood outlet 12 of the front module 2 is connected to the blood inlet 11 of the rear module 3 through the multiple flow holes 61. The radially outer end of the partition plate 6 is inserted into the gap space between the first sealing layer 22 and the second sealing layer 32, and the radially outer end of the partition plate 6 is opposite to the inner end of the second partition plate 42. This allows for quick fixation of the partition plate 6 and improves its installation stability. Furthermore, the first sealing layer 22 and the second sealing layer 32 provide a good seal, preventing leakage at the partition plate 6.

[0059] In another specific embodiment, a portion of the outer wall of the partition plate 6 extends radially outward to form a second partition plate 42, and the outer ends of the remaining portion of the partition plate 6 are inserted radially into the gap between the first sealing layer 22 and the second sealing layer 32. By forming the second partition plate 42 from a portion of the outer wall of the partition plate 6, the partition plate 6 and the second partition plate 42 are integrally formed, thereby allowing the outer ends of the remaining portion of the partition plate 6 to be inserted between the first sealing layer 22 and the second sealing layer 32, thus simultaneously fixing the partition plate 6 and the second partition plate 42 and improving installation efficiency. Preferably, the two second partition plates 42 are symmetrically arranged on the partition plate 6.

[0060] During actual installation, when one of the third partitions 51 abuts against the first position of the second partition 42 and one of the first partitions 41 abuts against the second position of the second partition 42, the third partition 51 and the first partition 41 will generate a torsional moment on the second partition 42, causing the second partition 42 to have a tendency to twist, which reduces the installation stability of the second partition 42.

[0061] To avoid the aforementioned problems, one of the third partitions 51 is angled at the same angle as one of the first partitions 41, and both abut against the upper and lower surfaces of one of the second partitions 42, respectively. Furthermore, another third partition 51 is angled at the same angle as another first partition 41, and both abut against the upper and lower surfaces of another second partition 42, respectively. This allows the forces exerted by the first partitions 41 and the third partitions 51 on the second partition 42 to cancel each other out, thereby eliminating the torque acting on the second partition 42 and improving its installation stability.

[0062] like Figure 7 As shown, blood inlet 11 and blood outlet 12 are respectively located at both ends of housing 1, with blood inlet 11 and blood outlet 12 being approximately perpendicular to the membrane fiber layer of the front module 2 and / or the membrane fiber layer of the rear module 3. Specifically, blood inlet 11 and blood outlet 12 can be respectively located on the first end cap 17 and the second end cap 18. By making blood inlet 11 and blood outlet 12 approximately perpendicular to the membrane fiber layer of the front module 2 and the membrane fiber layer of the rear module 3, blood can enter the front oxygenation membrane fiber layer and the rear oxygenation membrane fiber layer 31 vertically, eliminating dead zones in blood flow and enabling blood to be transported more efficiently along the blood channels, thereby improving the oxygenation efficiency of the blood.

[0063] Oxygenating medium inlet 15 and oxygenating medium outlet 16 are symmetrically arranged on the side wall of housing 1. Oxygenating medium inlet 15 is approximately parallel to the membrane fiber layer of the front module 2 and / or the membrane fiber layer of the rear module 3. In this way, the oxygenating medium can be vertically input into the front oxygenating membrane fiber layer and the rear oxygenating membrane fiber layer 31, thereby improving the oxygenating medium delivery efficiency.

[0064] like Figure 8 As shown, the oxygenation medium outlet 16 is a through hole provided on the housing 1, and multiple oxygenation medium outlets 16 can be provided. Multiple oxygenation medium outlets 16 are spaced apart along the axial direction of the housing 1, so that the oxygenation medium flowing out through the pre-oxygenation membrane fiber layer and the post-oxygenation membrane fiber layer 31 can flow out through multiple oxygenation medium outlets 16 at different heights, avoiding the problem of backflow of used oxygenation medium and improving the discharge efficiency of oxygenation medium.

[0065] Temperature-controlled medium inlet 13 and temperature-controlled medium outlet 14 are symmetrically arranged on the side wall of housing 1, and are approximately perpendicular to oxygenation medium inlet 15. Temperature-controlled medium inlet 13 and temperature-controlled medium outlet 14 are approximately parallel to the membrane fiber layer of the pre-module 2 and / or the membrane fiber layer of the post-module 3. In this way, the temperature-controlled medium can be vertically input into the pre-temperature-controlled membrane fiber layer, improving the delivery efficiency of the temperature-controlled medium, thereby better regulating the oxygenation temperature of the blood.

[0066] The various embodiments in this specification are described in a progressive manner, with each embodiment focusing on its differences from other embodiments. Similar or identical parts between embodiments can be referred to interchangeably. The above embodiments are only for illustrating the technical concept and features of the present invention, and are intended to enable those skilled in the art to understand the content of the present invention and implement it accordingly. They should not be construed as limiting the scope of protection of the present invention. All equivalent changes or modifications made according to the spirit and essence of the present invention should be covered within the scope of protection of the present invention.

Claims

1. An oxygenator, characterized in that, include: The casing has a blood inlet and a blood outlet; The pre-module, located within the housing, includes multiple stacked pre-units situated between the blood inlet and the blood outlet. Each pre-unit includes a stacked oxygenation membrane fiber layer and a temperature control membrane fiber layer. The rear module is located within the housing, between the front module and the blood outlet, and includes a stacked rear oxygenation membrane fiber layer. A rear sealing assembly is provided between the rear module and the housing, which divides the gap space between the rear module and the housing into two symmetrical third chambers and fourth chambers; one end of each of the rear oxygenation membrane fibers is connected to the third chamber, and the other end of each of the rear oxygenation membrane fibers is connected to the fourth chamber. A front sealing assembly is provided between the front module and the housing. The front sealing assembly and the front module further define a fifth chamber and a sixth chamber. The two ends of the oxygenated membrane fiber layer of the front module are respectively connected to the fifth chamber and the sixth chamber. The fifth chamber and the sixth chamber are open in the direction towards the rear module. The fifth chamber is connected to the third chamber, and the sixth chamber is connected to the fourth chamber.

2. The oxygenator as described in claim 1, characterized in that, Each of the aforementioned front-end units includes three stacked membrane fiber layers, with each pair of the three membrane fiber layers positioned at 120° intervals. The three membrane fiber layers include: one first front-end membrane fiber layer and two second front-end membrane fiber layers. The first front-end membrane fiber layer is either an oxygenation membrane fiber layer or a temperature control membrane fiber layer, and the second front-end membrane fiber layer is either an oxygenation membrane fiber layer or a temperature control membrane fiber layer. In all the aforementioned front-end units, the first front-end membrane fiber layer is positioned at the same angle.

3. The oxygenator as described in claim 2, characterized in that, The rear module includes three stacked rear oxygenation membrane filament layers, with each pair of the three rear oxygenation membrane filament layers positioned at 120° to the others.

4. The oxygenator as described in claim 3, characterized in that, The pre-sealing assembly and the pre-module define a closed first chamber and a second chamber. The two ends of the temperature-controlled membrane fiber layer are respectively connected to the first chamber and the second chamber. The housing is also provided with a temperature-controlled medium inlet and a temperature-controlled medium outlet. The temperature-controlled medium inlet is connected to one of the first chamber and the second chamber, and the temperature-controlled medium outlet is connected to the other of the first chamber and the second chamber.

5. The oxygenator as described in claim 4, characterized in that, The shell is further provided with an oxygenation medium inlet and an oxygenation medium outlet. The oxygenation medium inlet is connected to the third chamber and / or the fifth chamber, and the oxygenation medium outlet is connected to the fourth chamber and / or the sixth chamber.

6. The oxygenator as described in claim 5, characterized in that, The housing includes: a cylindrical body, a first end cap and a second end cap disposed at both ends of the cylindrical body along the axial direction; The front module further includes: a first sealing layer formed on the radial outer periphery of the membrane fiber layer; The front-mounted barrier assembly includes four first partitions and two second partitions; wherein each first partition extends axially and the four first partitions are arranged circumferentially; each second partition extends radially and the two second partitions are arranged circumferentially. The outer end of the first partition along the radial direction is connected to the inner wall of the cylindrical body, and the inner end of the first partition along the radial direction is connected to the first sealing layer; the outer end of the second partition along the radial direction is connected to the inner wall of the cylindrical body, and the inner end of the second partition along the radial direction is connected to the first sealing layer. One end of the first partition along the axial direction is connected to the first end cover; The four first partitions are arranged in pairs. The other ends of the two first partitions in the first group are connected to one of the second partitions along the axial direction, and the other ends of the two first partitions in the second group are connected to the other second partition along the axial direction. The first group has two first partitions and connected to them a second partition, a first end cap, and a cylindrical body defining the first chamber; the second group has two first partitions and connected to them a second partition, a first end cap, and a cylindrical body defining the second chamber; the first group and the second group have two adjacent first partitions and connected to them a first end cap and a cylindrical body defining the fifth chamber and the sixth chamber, respectively.

7. The oxygenator as described in claim 6, characterized in that, The rear module further includes: a second sealing layer formed on the radial outer periphery of the rear oxygen membrane filament layer; The rear-mounted partition assembly includes two third partitions; wherein each of the third partitions extends axially, and the two third partitions are arranged circumferentially at intervals. The outer end of the third partition plate is connected to the inner wall of the cylindrical body in the radial direction, and the inner end of the third partition plate is connected to the second sealing layer in the radial direction. One end of the third partition along the axial direction is connected to the second end cover; One of the third partitions is connected axially at one end to one of the second partitions, and the other of the third partitions is connected axially at one end to the other second partition; One of the third partitions and the second partition, the second end cap, and the cylindrical body connected thereto define the third chamber, and the other third partition and the second partition, the second end cap, and the cylindrical body connected thereto define the fourth chamber.

8. The oxygenator as described in claim 7, characterized in that, The oxygenator also includes: The partition plate includes a generally circular main body and a plurality of flow holes provided on the main body. The main body is located between the front module and the rear module. The blood outlet of the front module is connected to the blood inlet of the rear module through the flow holes. The outer radial end of the partition plate is inserted into the gap between the first sealing layer and the second sealing layer, and the outer radial end of the partition plate is positioned opposite to the inner end of the second partition plate; or A portion of the outer wall of the partition plate extends radially outward to form the second partition plate, and the remaining portion of the partition plate is inserted radially into the gap space between the first sealing layer and the second sealing layer.

9. The oxygenator as described in claim 7, characterized in that, One of the third partitions is angled at the same angle as one of the first partitions, and the two abut against the upper and lower surfaces of one of the second partitions, respectively; and / or The third partition is set at the same angle as the first partition, and the two abut against the upper and lower surfaces of the second partition, respectively.

10. The oxygenator as described in claim 5, characterized in that, The blood inlet and the blood outlet are respectively located at both ends of the housing, and the blood inlet and the blood outlet are approximately perpendicular to the membrane fiber layer of the front module and / or the membrane fiber layer of the rear module; and / or The oxygenation medium inlet and the oxygenation medium outlet are symmetrically arranged on the side wall of the housing, with the oxygenation medium inlet approximately parallel to the membrane fiber layer of the pre-module and / or the membrane fiber layer of the post-module; and / or The temperature-controlled medium inlet and the temperature-controlled medium outlet are symmetrically arranged on the side wall of the housing and are approximately perpendicular to the oxygenation medium inlet. The temperature-controlled medium inlet and the temperature-controlled medium outlet are approximately parallel to the membrane fiber layer of the front module and / or the membrane fiber layer of the rear module.

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