Oscillating mixing device, sample analysis system and control method thereof

Abstract

The application relates to the technical field of medical devices, in particular to an oscillation mixing device, a sample analysis system and a control method thereof. The oscillation mixing device comprises an oscillation assembly, including an oscillation turntable, an oscillation base, an oscillation support arranged on the oscillation base and capable of reciprocating along the radial direction of the oscillation turntable and an oscillation driving mechanism; a wave form assembly includes a wave form turntable and a wave form driving mechanism, the wave form turntable is provided with a plurality of alternating convex parts and concave parts, the oscillation support alternately abuts against the convex parts and the concave parts to reciprocate along the radial direction of the oscillation turntable; a base assembly includes a base and an incubation cover, the incubation cover is provided with an inlet and an outlet; an inlet and outlet assembly includes an inlet and outlet support fixedly connected with the incubation cover and a positioning piece group abutting against the oscillation support to lock the oscillation support at the inlet and the outlet. The oscillation mixing device, the sample analysis system and the control method solve the technical problem that substances on the mixing mechanism can be taken and placed in time without stopping the whole mixing work, and the cost is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to an oscillation mixing device, a sample analysis system and a control method thereof. BACKGROUND

[0002] In the field of sample analysis, common mixing methods include eccentric rotation oscillation and ultrasonic cavitation. To improve the use efficiency and space utilization of the sample analysis system, the mixing mechanism is usually set as a disc shape. For example, an invention patent with the title of "A fully automatic chemiluminescence immunoassay analyzer" and the authorization announcement number of CN111157753B is provided with multiple oscillation modules, which are driven by a rotating motor, so that the reagent in the reaction tube on the oscillation module can be mixed with the sample or the components of the reagent.

[0003] However, the substances (reagents or samples) on the mixing mechanism are consumables, that is, the types that will be used up need to be added in time, and the types that will not be used need to be taken away in time. To achieve this purpose, in the prior art, one implementable way is to stop the entire mixing mechanism or the mixing mechanism carrier, and then use a mechanical gripper to put new reaction tubes or take away unused reaction tubes. In this way, the entire reaction system needs to be stopped, which reduces the detection efficiency. Alternatively, another implementable way is to set a separate drive motor and control system for each oscillation mechanism, and then control the specific single oscillation mechanism when the substance (reagent or sample) needs to be added or taken away. However, this way will significantly increase the cost. SUMMARY

[0004] The purpose of the present application is to provide an oscillation mixing device, a sample analysis system and a control method thereof, to solve the technical problem of timely taking away and adding the substances on the mixing mechanism without stopping the entire mixing work, and to reduce the cost at the same time.

[0005] In a first aspect, the present application provides an oscillation mixing device, comprising:

[0006] an oscillation assembly, comprising an oscillation turntable, an oscillation base fixedly connected with the oscillation turntable, an oscillation support arranged on the oscillation base and capable of reciprocating along the radial direction of the oscillation turntable, and an oscillation drive mechanism for driving the oscillation turntable to rotate;

[0007] a wave form assembly, comprising a wave form turntable and a wave form drive mechanism for driving the wave form turntable to rotate, the wave form turntable being provided with a plurality of alternating convex portions and concave portions, and the oscillation support being capable of alternately abutting against the convex portions and the concave portions to reciprocate along the radial direction of the oscillation turntable;

[0008] The base assembly comprises a base supporting the oscillation turntable and the wave turntable, and an incubation cover arranged above the oscillation turntable and fixedly connected with the base, wherein an inlet and outlet are arranged on the incubation cover.

[0009] The inlet and outlet assembly comprises an inlet and outlet support and a positioning component group arranged on the inlet and outlet support, wherein the inlet and outlet support is fixedly connected with the incubation cover, and the positioning component group is capable of abutting against the oscillation support to lock the oscillation support at the inlet and outlet.

[0010] Further, a plurality of oscillation bases are fixedly connected to the oscillation turntable along the circumference thereof.

[0011] The incubation cover comprises a top cover and a circumferential sidewall extending downward along the circumferential edge of the top cover, wherein the inlet and outlet are arranged on the top cover, and the inlet and outlet support is fixedly connected with the circumferential sidewall and arranged in a spaced manner with the wave turntable.

[0012] Further, the oscillation assembly further comprises an oscillation reset component, which forces the oscillation support to move towards the convex portion or the concave portion.

[0013] Further, the oscillation reset component is a compression elastic component, one end of which abuts against the oscillation base, and the other end of which abuts against the oscillation support.

[0014] The positioning component group comprises a first buffer roller, an inlet and outlet roller pair and a second buffer roller arranged in sequence along the rotation direction of the wave turntable.

[0015] The oscillation support comprises an oscillation locking component capable of abutting against the first buffer roller, the inlet and outlet roller pair and the second buffer roller respectively, and an oscillation abutting component capable of abutting against the convex portion and the concave portion alternately, wherein the oscillation locking component and the oscillation abutting component are located on the opposite side of the oscillation support relative to the compression elastic component.

[0016] When the oscillation locking component abuts against the first buffer roller, the inlet and outlet roller pair and the second buffer roller respectively, the compression elastic component has a first stroke S1, a second stroke S2 and a third stroke S3 respectively.

[0017] When the oscillation abutting component abuts against the convex portion and the concave portion respectively, the compression elastic component has a low position stroke L and a high position stroke M respectively.

[0018] Wherein, L < S1 < M, L < S3 < M, and S2 < L.

[0019] Further, the oscillation support further comprises a containing cavity containing a reaction container.

[0020] The inlet and outlet roller pair comprises an inlet roller and an outlet roller.

[0021] The inlet and outlet comprise an inlet port and an outlet port;

[0022] The oscillation locking member is an oscillation protrusion, and the oscillation abutting member is an oscillation roller;

[0023] When the oscillation protrusion abuts against the inlet roller, the accommodating cavity is located below the inlet port; and when the oscillation protrusion abuts against the outlet roller, the accommodating cavity is located below the outlet port.

[0024] Further, the oscillation turntable is coaxially arranged with the wave-shaped turntable, and when oscillation mixing is performed, the wave-shaped turntable rotates at a first angular velocity, and the oscillation turntable rotates at a second angular velocity different from the first angular velocity.

[0025] Further, the wave-shaped assembly further comprises a wave-shaped turntable support fixedly connected with the wave-shaped turntable, and a first turntable fixedly connected with the wave-shaped turntable support and arranged opposite to the wave-shaped turntable;

[0026] The wave-shaped driving mechanism comprises a first motor fixedly connected with the base and a first belt in transmission connection with the first motor, and the first belt is also in transmission connection with the first turntable;

[0027] The oscillation assembly further comprises an oscillation turntable support fixedly connected with the oscillation turntable, and a second turntable fixedly connected with the oscillation turntable support and arranged opposite to the oscillation turntable;

[0028] The oscillation driving mechanism comprises a second motor fixedly connected with the base and a second belt in transmission connection with the second motor, and the second belt is also in transmission connection with the second turntable.

[0029] Further, the oscillation mixing device further comprises a stabilizing assembly comprising a stabilizing seat fixedly connected with the base, a stabilizing motor arranged on the stabilizing seat, and a stabilizing pin driven by the stabilizing motor to ascend or descend, wherein the stabilizing pin is located below the positioning member group;

[0030] The oscillation base is provided with a stabilizing hole, and the stabilizing pin can ascend to pass through the stabilizing hole or descend to be separated from the stabilizing hole.

[0031] In a second aspect, the application provides a control method for a sample analysis system, wherein the sample analysis system comprises the oscillation mixing device according to any one of the preceding aspects and a control device for controlling the oscillation mixing device, and the control method comprises the following steps:

[0032] A to-be-oscillated mixing step is determined, and the control device receives an instruction to determine a target oscillation support;

[0033] an oscillation mixing step, the wave-shaped turntable rotates at a first angular velocity, the oscillation turntable rotates at a second angular velocity different from the first angular velocity;

[0034] an end oscillation mixing step, the wave-shaped turntable still rotates at the first angular velocity, the target oscillation support rotates to the inlet and outlet and is locked by the positioning member set, and the oscillation turntable stops rotating.

[0035] Further, the sample analysis system further comprises a taking and placing device, and after the end oscillation mixing step, the control method further comprises: the taking and placing device taking and placing the sample subjected to the oscillation mixing from the inlet and outlet.

[0036] In a third aspect, the present application provides a sample analysis system, comprising the oscillation mixing device according to any one of the preceding aspects, a control device for controlling the oscillation mixing device, and a taking and placing device for taking and placing the sample from the inlet and outlet.

[0037] Compared with the prior art, in the oscillation process, when it is necessary to take away or replace or add the reagent or sample, the oscillation support on which the reagent or sample is located is rotated to the inlet and outlet of the incubation cover, the positioning member set can be in contact with the oscillation support to lock the oscillation support at the inlet and outlet, at this time, the reagent or sample can be taken away or placed in through the inlet and outlet by the taking and placing device such as a gripper; however, at the same time, the wave-shaped turntable does not stop working, so that the whole mixing and oscillation work continues when the reagent or sample is taken away or added, and each oscillation support can be controlled by one wave-shaped turntable, and it is not necessary to set an independent driving mechanism for each oscillation support to achieve the control, thereby greatly reducing the cost. The present application not only solves the problem of timely taking away or adding the reagent or sample on the mixing and oscillation mechanism, but also does not need to stop the whole mixing and oscillation mechanism, improves the mixing and oscillation work efficiency, and does not need to set an independent driving mechanism for each oscillation support, thereby greatly reducing the cost.

[0038] In the oscillation process, when it is necessary to take away or replace or add the reagent or sample, the oscillation support on which the reagent or sample is located is rotated to the inlet and outlet of the incubation cover, the positioning member set can be in contact with the oscillation support to lock the oscillation support at the inlet and outlet, at this time, the reagent or sample can be taken away or placed in through the inlet and outlet by the taking and placing device such as a gripper; however, at the same time, the wave-shaped turntable does not stop working, so that the whole mixing and oscillation work continues when the reagent or sample is taken away or added, and each oscillation support can be controlled by one wave-shaped turntable, and it is not necessary to set an independent driving mechanism for each oscillation support to achieve the control, thereby greatly reducing the cost. The present application not only solves the problem of timely taking away or adding the reagent or sample on the mixing and oscillation mechanism, but also does not need to stop the whole mixing and oscillation mechanism, improves the mixing and oscillation work efficiency, and does not need to set an independent driving mechanism for each oscillation support, thereby greatly reducing the cost. BRIEF DESCRIPTION OF DRAWINGS

[0039] In order to more clearly illustrate the technical solutions in the specific embodiments or the prior art of the present application, the drawings needed to be used in the description of the specific embodiments or the prior art will be briefly introduced. Obviously, the drawings in the following description are some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0040] Figure 1 The overall structure schematic diagram of the oscillation mixing device provided by the embodiments of the present application;

[0041] Figure 2 The overall explosion diagram of the oscillation mixing device provided by the embodiments of the present application;

[0042] Figure 3 The structure schematic diagram of the oscillation base and the oscillation support provided by the embodiments of the present application;

[0043] Figure 4 The structure schematic diagram of the in-out assembly provided by the embodiments of the present application;

[0044] Figure 5 The use state schematic diagram of the in-out assembly and the oscillation support provided by the embodiments of the present application;

[0045] Figure 6 The structure sectional view schematic diagram of the oscillation assembly provided by the embodiments of the present application;

[0046] Figure 7 The partial structure schematic diagram of the oscillation mixing device provided by the embodiments of the present application;

[0047] Figure 8 The overall sectional view of the oscillation mixing device provided by the embodiments of the present application;

[0048] Figure 9 The partial structure enlarged view of Figure 8 .

[0049] Reference signs:

[0050] 100-oscillation mixing device;

[0051] 10-oscillation assembly;

[0052] 11-oscillation turntable;

[0053] 12-oscillation base;

[0054] 121-stabilizing hole;

[0055] 13-oscillation support;

[0056] 131-oscillation protrusion;

[0057] 132 - oscillating roller;

[0058] 133 - oscillating pin;

[0059] 134 - partition;

[0060] 315 - accommodating cavity;

[0061] 14 - oscillating reset member;

[0062] 15 - oscillating turntable support;

[0063] 161 - second turntable;

[0064] 162 - second motor;

[0065] 163 - second belt;

[0066] 20 - wave-shaped assembly;

[0067] 21 - wave-shaped turntable;

[0068] 211 - convex portion;

[0069] 212 - concave portion;

[0070] 22 - wave-shaped turntable support;

[0071] 231 - first turntable;

[0072] 232 - first motor;

[0073] 233 - first belt;

[0074] 30 - base;

[0075] 31 - base shaft;

[0076] 40 - incubation cover;

[0077] 41 - top cover;

[0078] 411 - inlet and outlet;

[0079] 4111 - inlet;

[0080] 4112 - outlet;

[0081] 42 - circumferential side wall;

[0082] 421 - mounting notch;

[0083] 431 - incubation cover support;

[0084] 432 - incubation cover support disc;

[0085] 50 - inlet and outlet assembly;

[0086] 51 - in and out bearing;

[0087] 521 - first buffer roller;

[0088] 522 - second buffer roller;

[0089] 523 - in roller;

[0090] 524 - out roller;

[0091] 525 - transmission roller;

[0092] 53 - rotation shaft;

[0093] 60 - stabilizing assembly;

[0094] 61 - stabilizing seat;

[0095] 62 - stabilizing motor;

[0096] 63 - stabilizing pin;

[0097] 70 - reaction vessel. DETAILED DESCRIPTION

[0098] So that the purposes, technical solutions and advantages of the embodiments of the present application are more apparent, the technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are some embodiments of the present application, but not all embodiments of the present application. The components of the embodiments of the present application described and shown in the drawings herein can be arranged and designed in various different configurations.

[0099] Therefore, the following detailed description of the embodiments of the present application provided in the drawings is not intended to limit the scope of the claimed present application, but only represents selected embodiments of the present application. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present application without creative labor are within the scope of protection of the present application.

[0100] It should be noted that similar reference numbers and letters represent similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not need to be further defined and explained in subsequent drawings.

[0101] In the description of the present application, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and the like indicate the orientation or positional relationship shown in the drawings or the orientation or positional relationship commonly used when the product of the present application is used, and are merely intended to facilitate the description of the present application and simplify the description, and therefore cannot be understood as indicating or implying that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application. In addition, the terms "first", "second", "third" and the like are only used to distinguish the description and cannot be understood as indicating or implying relative importance.

[0102] In addition, the terms "horizontal", "vertical", "overhanging" and the like do not mean that the components must be absolutely horizontal or overhanging, but can be slightly inclined. For example, "horizontal" only means that it is more horizontal relative to "vertical", and does not mean that the structure must be completely horizontal, but can be slightly inclined.

[0103] In the description of the present application, it should be noted that unless otherwise explicitly specified and limited, the terms "arrangement", "installation", "connection", "connection" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0104] Some embodiments of the present application will be described in detail below with reference to the accompanying drawings. The following examples and features in the examples can be combined with each other without conflict.

[0105] As shown in Figures 1 to 9 , the embodiments of the present application provide an oscillation mixing device 100, a sample analysis system applying the oscillation mixing device 100, and a control method for the sample analysis system.

[0106] As shown in Figure 1 and 2 , the oscillation mixing device 100 provided by the embodiments of the present application mainly includes an oscillation assembly 10, a waveform assembly 20, a base assembly, and an in-out assembly 50. As shown in Figure 2 and Figure 3As shown, the oscillation assembly 10 comprises an oscillation turntable 11, an oscillation base 12 fixedly connected with the oscillation turntable 11, an oscillation support 13 arranged on the oscillation base 12 and capable of reciprocating along the radial direction of the oscillation turntable 11, and an oscillation driving mechanism for driving the oscillation turntable 11 to rotate. As the name implies, the oscillation turntable 11 is generally a disc, and the radial direction thereof can be any point outside the rotation axis on the rotation plane pointing to the direction of the rotation axis. The oscillation support 13 is provided with a receiving cavity 315 for receiving a reaction container 70, and the reaction container 70 is internally provided with reagents or samples or other articles.

[0107] As shown in Figure 2 , the foregoing wave-shaped assembly 20 comprises a wave-shaped turntable 21 and a wave-shaped driving mechanism for driving the wave-shaped turntable 21 to rotate. The wave-shaped turntable 21 is provided with a plurality of alternating convex portions 211 and concave portions 212, and the foregoing oscillation support 13 can alternately abut against the convex portions 211 and the concave portions 212 to reciprocate in the radial direction of the foregoing oscillation turntable 11. The abutment mentioned in the embodiments of the present application means abutting contact.

[0108] As shown in Figure 2 , the foregoing base assembly comprises a base 30 for rotatingly supporting the foregoing oscillation turntable 11 and the wave-shaped turntable 21, and an incubation cover 40 arranged above the foregoing oscillation turntable 11 and fixedly connected with the base 30. The incubation cover 40 is provided with an inlet and outlet 411 for articles such as reagents, samples or reaction containers 70 to enter and exit. The inlet and outlet 411 can specifically comprise an inlet port 4111 and an outlet port 4112.

[0109] As shown in Figure 2 and Figure 4 , the foregoing inlet and outlet assembly 50 comprises an inlet and outlet support 51 and a positioning member set arranged on the inlet and outlet support 51. The inlet and outlet support 51 is fixedly connected with the foregoing incubation cover 40, and the positioning member set can abut against the foregoing oscillation support 13 to lock the oscillation support 13 at the foregoing inlet and outlet 411.

[0110] Compared with the prior art, the oscillation mixing device 100 provided by the embodiment of the application, when oscillating, the oscillation driving mechanism and the waveform driving mechanism control the rotation of the oscillation turntable 11 and the rotation of the waveform turntable 21 respectively, the oscillation turntable 11 rotates while the waveform turntable 21 rotates, the oscillation support 13 alternately abuts against the convex part 211 and the concave part 212 of the waveform turntable 21, when the convex part 211 abuts against the oscillation support 13, the oscillation support 13 moves along the radial direction of the oscillation turntable 11 to the low stroke state (that is, the compression elastic member is in the state of being extruded and contracted), when the concave part 212 abuts against the oscillation support 13, the oscillation support 13 moves along the radial direction of the oscillation turntable 11 to the high stroke state (that is, the compression elastic member is in the state of relaxation), and the oscillation support 13 realizes the oscillation effect through the alternating reciprocating movement, and further drives the reagent or sample and other articles mounted thereon to oscillate, so as to realize the overall oscillation and mixing effect.

[0111] In the oscillation process, when it is needed to take away or replace or add reagents or samples or reaction containers 70 and other articles, the oscillation support 13 where the article is located is turned to the inlet and outlet 411 of the incubation cover 40, the positioning piece group can abut against the oscillation support 13 to lock the oscillation support 13 at the inlet and outlet 411, at this time, the reagent or sample and other articles can be taken away or placed in through the inlet and outlet 411 by the taking and placing device such as a gripper; however, at the same time, the waveform turntable 21 does not stop working, so that the whole mixing and oscillation work is still continued when the article is taken away or added, and each oscillation support 13 can be controlled by one waveform turntable 21, and it is not necessary to separately set an independent driving mechanism for each oscillation support 13 to realize the control, so that the cost is greatly reduced.

[0112] The embodiment of the application solves the problem that the article on the oscillation and mixing device can be taken away or added in time, and at the same time, the whole oscillation and mixing device does not need to stop working, the efficiency of the oscillation and mixing work is improved, and each oscillation support 13 does not need to be separately provided with a driving mechanism, so that the cost is greatly reduced.

[0113] A preferred embodiment is that the aforementioned incubation cover 40 comprises a top cover 41 and a circumferential sidewall 42 extending downwardly along a circumferential edge of the top cover 41, the aforementioned inlet and outlet 411 is arranged on the top cover 41, the aforementioned inlet and outlet assembly 50 is arranged on the circumferential sidewall 42, in particular, the circumferential sidewall 42 has an installation notch 421 corresponding to the position where the inlet and outlet assembly 50 is arranged, the inlet and outlet assembly 50 is arranged at the position of the installation notch 421, and the inlet and outlet support 51 of the inlet and outlet assembly 50 is fixedly connected with the installation notch 421 of the circumferential sidewall 42. In particular, the top cover 41 can be located above the aforementioned oscillation turntable 11, and the circumferential sidewall 42 is preferably located at the periphery of the oscillation turntable 11, a plurality of the aforementioned oscillation bases 12 are fixedly connected with the oscillation turntable 11 along the circumference thereof, so that the inlet and outlet assembly 50 can be arranged opposite to the oscillation bracket 13 on the oscillation base 12, and the inlet and outlet assembly 50 can abut against the oscillation bracket 13.

[0114] Further, in order to avoid the mutual influence and interference between the work of the inlet and outlet assembly 50 and the oscillation bracket 13 and the work between the convex portion 211 and the concave portion 212 of the wave-shaped turntable 21 and the oscillation bracket 13, the inlet and outlet assembly 50 is arranged spaced apart from the wave-shaped turntable 21, as shown in Figure 8 and Figure 9 The wave-shaped turntable 21 is preferably arranged rotating at the periphery of the oscillation turntable 11 and spaced apart from the inlet and outlet assembly 50.

[0115] A specific embodiment is that, as shown in Figure 6 The aforementioned oscillation assembly 10 further comprises an oscillation reset member 14, which forces the oscillation bracket 13 to move towards the convex portion 211 or the concave portion 212 of the wave-shaped turntable 21. The oscillation reset member 14 can be a compression elastic member, in particular, a compression spring, one end of which abuts against the aforementioned oscillation base 12, and the other end of which abuts against the oscillation bracket 13.

[0116] Another specific embodiment is that, as shown in Figures 4 to 6As shown, the positioning component of the aforementioned access assembly 50 includes a first buffer roller 521, an access roller pair, and a second buffer roller 522 arranged in sequence along the rotation direction of the aforementioned wave-shaped turntable 21, the access roller pair includes an in roller 523 and an out roller 524, the first buffer roller 521, the in roller 523, the out roller 524, and the second buffer roller 522 are rotationally connected to the access support 51 through the rotation shaft 53, the first buffer roller 521 is arranged to enable the oscillation support 13 to have a buffering process when entering the access assembly 50, so that the substance in the reaction container 70 can be in advance from the oscillation state to the static state, and the gripper device is more stable when grabbing.

[0117] Further, the aforementioned oscillation support 13 includes an oscillation locking member that can be in contact with the aforementioned first buffer roller 521, the access roller pair, and the second buffer roller 522, respectively, and an oscillation contact member that can be in contact with the convex portion 211 and the concave portion 212 of the aforementioned wave-shaped turntable 21 alternately, the oscillation locking member and the oscillation contact member are located on the opposite side of the aforementioned oscillation support 13 and the aforementioned compression elastic member, and the opposite side is preferably arranged close to the circumferential edge of the aforementioned oscillation turntable 11. When the oscillation locking member is in contact with the first buffer roller 521, the access roller pair, and the second buffer roller 522, respectively, the aforementioned compression elastic member has a first stroke S1, a second stroke S2, and a third stroke S3, respectively; when the oscillation contact member is in contact with the convex portion 211 and the concave portion 212 of the wave-shaped turntable 21, respectively, the aforementioned compression elastic member has a low stroke L and a high stroke M, respectively; and the first stroke S1, the second stroke S2, and the third stroke S3, and the low stroke L and the high stroke M have the following relationship: L < S1 < M, L < S3 < M, and S2 < L. In order to make the oscillation support 13 to be locked realize the function of slow locking and slow recovery, and make the grabbing more stable.

[0118] A specific embodiment is as shown in Figure 3 and Figure 6 As shown, the aforementioned oscillation locking member can be an oscillation protrusion 131, when the oscillation protrusion 131 is in contact with the aforementioned in roller 523, the accommodation cavity 315 on the aforementioned oscillation support 13 for accommodating the reaction container 70 is located below the aforementioned in port 4111, when the oscillation protrusion 131 is in contact with the aforementioned out roller 524, the accommodation cavity 315 is located below the aforementioned out port 4112.

[0119] Another specific embodiment is that the aforementioned oscillation abutment is specifically an oscillation roller 132, the bottom of the aforementioned oscillation support 13 near one side of the circumferential edge of the aforementioned oscillation turntable 11 is provided with the oscillation roller 132, and an oscillation pin shaft 133 for mounting the oscillation roller 132, the bottom of the oscillation support 13 is also provided with a partition plate 134 which is arranged in a spaced manner with the oscillation roller 132, and the two ends of the aforementioned compression spring are respectively abutted on the partition plate 134 and the side wall of the oscillation base 12 away from the circumferential edge of the oscillation turntable 11.

[0120] Another preferred embodiment is that the aforementioned oscillation turntable 11 is coaxially arranged with the aforementioned wave-shaped turntable 21, when oscillation mixing is performed, the wave-shaped turntable 21 rotates at a first angular velocity, and the oscillation turntable 11 rotates at a second angular velocity different from the first angular velocity. In one case, the oscillation turntable 11 and the wave-shaped turntable 21 are coaxially arranged in the same direction, at this time, the two have a relative speed, which can promote the oscillation support 13 to reciprocate between the high position and the low position at all times, improving the mixing efficiency; in another case, the oscillation turntable 11 and the wave-shaped turntable 21 are coaxially arranged in opposite directions, so that the first motor 232 and the second motor 162 only need a small speed to realize the oscillation support 13 to reciprocate between the high position and the low position at all times, shortening the detection time and improving the detection efficiency.

[0121] A specific embodiment is that, as shown in Figure 2 , Figure 7 , Figure 8 and Figure 9 , the aforementioned wave-shaped assembly 20 further comprises a wave-shaped turntable support 22 fixedly connected with the wave-shaped turntable 21, and a first turntable 231 fixedly connected with the wave-shaped turntable support 22 and arranged opposite to the wave-shaped turntable 21, and the aforementioned wave-shaped driving mechanism comprises a first motor 232 fixedly connected with the aforementioned base 30 and a first belt 233 in transmission connection with the first motor 232 and the first turntable 231. The aforementioned oscillation assembly 10 further comprises an oscillation turntable support 15 fixedly connected with the aforementioned oscillation turntable 11, and a second turntable 161 fixedly connected with the oscillation turntable support 15 and arranged opposite to the oscillation turntable 11; the aforementioned oscillation driving mechanism comprises a second motor 162 fixedly connected with the base 30 or the incubation cover support disc 432, and a second belt 163 in transmission connection with the second motor 162 and the second turntable 161. The aforementioned incubation cover 40 further comprises an incubation cover support column 431 fixedly connected with the aforementioned circumferential side wall 42, and an incubation cover support disc 432 fixedly connected with the base shaft 31 of the aforementioned base 30.

[0122] In addition, as shown in Figure 7As shown, the oscillation mixing device 100 provided by the embodiments of the present application further comprises a stabilizing assembly 60, which comprises a stabilizing base 61 fixedly connected to the aforementioned base 30 through the incubation cover support disc 432, a stabilizing motor 62 arranged on the stabilizing base 61, and a stabilizing pin 63 driven by the stabilizing motor 62 to ascend or descend, the stabilizing pin 63 being located below the positioning assembly. Correspondingly, the aforementioned oscillation base 12 is provided with a stabilizing hole 121, and the stabilizing pin 63 can ascend to pass through the stabilizing hole 121 or descend to be separated from the stabilizing hole 121. In this way, the positioning can be more accurate, and the gripper can accurately grasp.

[0123] The sample analysis system provided by the embodiments of the present application comprises the aforementioned oscillation mixing device 100, a control device for controlling the movement of the oscillation mixing device 100, and a taking and placing device for taking and placing samples from the aforementioned inlet and outlet 411. The control device marks a target oscillation support that needs to take and place reagents or samples, etc., and controls the positioning assembly to lock the target oscillation support when the target oscillation support turns to the inlet and outlet 411 of the incubation cover 40. In a specific embodiment, the control device comprises oscillation sensors arranged on each oscillation base 12, and inlet and outlet sensors arranged at the inlet and outlet 411 and capable of being inducted by the oscillation sensors.

[0124] The control method for the sample analysis system provided by the embodiments of the present application comprises:

[0125] 1. A determination of the oscillation mixing step, the control device receives an instruction to determine a target oscillation support;

[0126] 2. An oscillation mixing step, the wave-shaped turntable rotates at a first angular velocity, and the oscillation turntable rotates at a second angular velocity different from the first angular velocity;

[0127] 3. An end of the oscillation mixing step, the wave-shaped turntable still rotates at the first angular velocity, the target oscillation support rotates to the inlet and outlet and is locked by the positioning assembly, and the oscillation turntable stops rotating;

[0128] 4. A step of taking and placing the sample completed with oscillation mixing by the taking and placing device from the inlet and outlet.

[0129] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present application, but not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: they can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application.

Claims

1. An oscillating mixing device, characterized in that, include: An oscillation assembly includes an oscillation turntable, an oscillation base fixedly connected to the oscillation turntable, an oscillation support disposed on the oscillation base and capable of reciprocating radially along the oscillation turntable, and an oscillation drive mechanism for driving the oscillation turntable to rotate. A waveform assembly includes a waveform turntable and a waveform drive mechanism for driving the waveform turntable to rotate. The waveform turntable is provided with a plurality of alternating protrusions and recesses. The oscillation support can alternately abut against the protrusions and recesses to reciprocate radially in the oscillation turntable. The base assembly includes a base that rotatably supports the oscillating turntable and the waveform turntable, and an incubation cover that covers the oscillating turntable and is fixedly connected to the base, the incubation cover having an inlet and outlet for items to enter and exit; An inlet / outlet assembly includes an inlet / outlet support and a positioning component assembly disposed on the inlet / outlet support. The inlet / outlet support is fixedly connected to the incubation cover, and the positioning component assembly can abut against the oscillation bracket to lock the oscillation bracket at the inlet / outlet. The oscillation assembly further includes an oscillation reset member, which forces the oscillation bracket to move toward the protrusion or the recess. The oscillation reset member is a compression elastic member, with one end abutting against the oscillation base and the other end abutting against the oscillation bracket. The positioning component group includes a first buffer roller, an inlet / outlet roller pair, and a second buffer roller arranged sequentially along the rotation direction of the wave-shaped turntable. The oscillation bracket includes an oscillation locking member that can respectively abut against the first buffer roller, the inlet / outlet roller pair and the second buffer roller, and an oscillation abutting member that can alternately abut against the protrusion and the recess. The oscillation locking member and the oscillation abutting member are both located on the opposite side of the oscillation bracket and the side that abuts against the compression elastic member. When the oscillation locking member abuts against the first buffer roller, the inlet / outlet roller pair, and the second buffer roller respectively, the compression elastic member has a first stroke S1, a second stroke S2, and a third stroke S3 respectively. When the oscillating contact member abuts against the protrusion and the concave portion respectively, the compression elastic member has a low stroke L and a high stroke M respectively; Where L < S1 < M, L < S3 < M, and S2 < L.

2. The oscillating mixing device according to claim 1, characterized in that, Multiple oscillating bases are fixedly connected to the oscillating turntable along its circumference; The incubation cover includes a top cover and a circumferential sidewall extending downward along the circumferential edge of the top cover. The inlet and outlet are disposed on the top cover, and the inlet and outlet support is fixedly connected to the circumferential sidewall and spaced apart from the wave-shaped turntable.

3. The oscillating mixing device according to claim 2, characterized in that, The oscillation support also includes a receiving cavity for accommodating the reaction vessel; The inlet and outlet roller pair includes an inlet roller and an outlet roller; The inlet and outlet include the inlet and outlet; The oscillation locking component is an oscillation protrusion, and the oscillation abutment component is an oscillation roller; When the oscillating protrusion abuts against the feed roller, the receiving cavity is located below the feed port; when the oscillating protrusion abuts against the discharge roller, the receiving cavity is located below the discharge port.

4. The oscillating mixing device according to any one of claims 1 to 3, characterized in that The oscillating turntable and the waveform turntable are coaxially arranged. During oscillation and mixing, the waveform turntable rotates at a first angular velocity, and the oscillating turntable rotates at a second angular velocity different from the first angular velocity.

5. The oscillating mixing device according to any one of claims 1 to 3, wherein The waveform assembly further includes a waveform turntable bracket fixedly connected to the waveform turntable, and a first turntable fixedly connected to the waveform turntable bracket and disposed opposite to the waveform turntable; The waveform driving mechanism includes a first motor fixedly connected to the base and a first belt drivenly connected to the first motor. The first belt is also drivenly connected to the first turntable. The oscillation assembly further includes an oscillation turntable bracket fixedly connected to the oscillation turntable and a second turntable fixedly connected to the oscillation turntable bracket and disposed opposite to the oscillation turntable; The oscillation drive mechanism includes a second motor fixedly connected to the base and a second belt driven by the second motor. The second belt is also driven by the second turntable.

6. The oscillating mixing apparatus according to any one of claims 1 to 3, characterized in that, The oscillating mixing device further includes a stabilizing component, which includes a stabilizing base fixedly connected to the base, a stabilizing motor disposed on the stabilizing base, and a stabilizing pin that is driven by the stabilizing motor to rise or fall, the stabilizing pin being located below the positioning component assembly; The oscillation base is provided with a stabilizing hole, and the stabilizing pin can rise to pass through the stabilizing hole or fall to disengage from the stabilizing hole.

7. A control method for a sample analysis system, characterized in that, The sample analysis system includes the oscillating and mixing device as described in any one of claims 1 to 6 and a control device for controlling the oscillating and mixing device, wherein the control method includes: The control device receives instructions to determine the target oscillation support for the step to be oscillated and mixed. In the oscillation and mixing step, the waveform turntable rotates at a first angular velocity, and the oscillation turntable rotates at a second angular velocity different from the first angular velocity; After the oscillation and mixing step ends, the waveform turntable continues to rotate at the first angular velocity, the target oscillation bracket rotates to the inlet and outlet and is locked by the positioning component group, and the oscillation turntable stops rotating.

8. The control method for a sample analysis system according to claim 7, characterized in that, The sample analysis system also includes a pick-and-place device. After the oscillation and mixing step is completed, the control method further includes the step of the pick-and-place device picking up and placing the sample that has been oscillated and mixed from the inlet and outlet.

9. A sample analysis system, characterized in that, The device includes the oscillating and mixing apparatus according to any one of claims 1 to 6, the control device for controlling the movement of the oscillating and mixing apparatus, and the sample taking and putting device for taking and putting samples from the inlet and outlet.

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