A kind of Chinese medicinal rice paper with physical therapy effect and preparation method thereof
By preparing traditional Chinese medicine rice paper with physiotherapy effects, combined with traditional moxibustion methods, the problem of slow efficacy of traditional physical therapy methods is solved, and the effect of multiple physiotherapy is improved. It is especially suitable for yang deficiency constitution and provides a more effective Chinese medicine physiotherapy plan.
Patent Information
- Application Number
- CN202311166974.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-09-12
- Publication Date
- 2024-12-20
- Estimated Expiration
- 2043-09-12
AI Technical Summary
Traditional Chinese medicine physiotherapy methods such as moxibustion have limited effects in warming yang and unblocking meridians, promoting blood circulation and dispersing blood stasis, and cannot simultaneously relieve exterior and dispel cold, dispel wind and dampness, nourish the liver and kidneys, strengthen muscles and bones, and stop numbness and pain, resulting in slow efficacy.
A Chinese herbal rice paper with physiotherapy effects is adopted. The preparation method includes boiling and filtration of Chinese herbal liquid, combining the preparation of mulberry paper, and adding Chinese herbal liquid to form paper with water absorption characteristics, which is used to prepare moxibustion strips and hot compress pads. Paper or directly serve as moxibustion mud.
This method not only increases the effects of understanding the surface and dispelling cold, dispelling wind and dampness, nourishing liver and kidneys, strengthening muscles and bones, and stopping pain on the basis of traditional moxibustion, but also improves the efficacy of physical therapy, especially suitable for yang deficiency constitution, and product packaging It is convenient to use later and has better efficacy than traditional mulberry paper patches.
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Abstract
Description
Technical Field
[0001] The invention relates to the field of traditional Chinese medicine, and in particular to a Chinese medicine rice paper with physiotherapy effect and a preparation method thereof. Background Art
[0002] Traditional Chinese medicine has been confirmed in the context of the rapid development of modern medicine and has gained increasing attention in the international arena.
[0003] The human body is a self-regulating, self-recovering and self-building system. According to Chinese medicine, under normal circumstances, the body maintains a relative dynamic balance of qi, blood, yin and yang, day and night, and rising and falling. The human body maintains the result of the unity of opposites in the two aspects of yin and yang, that is, "balance of yin and yang, unity of heaven and man". People with yang deficiency constitution are more likely to have sub-health status, accounting for about 6.2%-23.1% of all constitutions. Clinical studies have shown that the main clinical manifestations of yang deficiency sub-health are cold limbs, cold accumulation in the body, susceptibility to fatigue, and decreased reaction, logical thinking and other abilities.
[0004] Traditional Chinese medicine believes that traditional physical therapy methods such as moxibustion, warm needles, and hot compress massage have a positive therapeutic effect on related diseases. However, there are disadvantages of single methods and slow efficacy. For example, traditional moxibustion therapy can only achieve the effects of warming the yang and unblocking the meridians, activating blood circulation and removing blood stasis, and raising yang energy through the warm stimulation of moxibustion and the drug stimulation of moxa during implementation, but it cannot take into account the effects of relieving cold, dispelling wind and dampness, nourishing the liver and kidneys, strengthening muscles and bones, and relieving pain. This is also one of the main reasons why traditional physical therapy methods are generally slow to take effect. Summary of the invention
[0005] The purpose of the present invention is to overcome the shortcomings of the prior art and provide a kind of Chinese medicinal rice paper with physiotherapy effect and a preparation method thereof, which is easy to use and has a wide range of uses, and has the effects of dispelling cold, removing wind and dampness, nourishing the liver and kidney, strengthening muscles and bones, and relieving arthralgia, so as to promote the physiotherapy effect of multiple physiotherapy means.
[0006] The method for preparing the Chinese medicinal rice paper with therapeutic effect comprises the following steps:
[0007] Step 1. Preparation of Chinese medicine solution
[0008] 1. Use mugwort leaves, ginger, angelica root, angelica pubescens, Chuanwu, Caowu, Tianxianteng, Chuanxuduan, Sanguisorba officinalis, Pteris cretica, Viscum album, Eucommia bark, Cat's Claw, Rhizoma Smilacis Glabrae, and licorice as traditional Chinese medicine, boil them in water, filter the residue, and make a traditional Chinese medicine liquid for later use.
[0009] Preferably, the ratio of the above-mentioned traditional Chinese medicine composition and water is as follows: the ratio of mugwort, ginger, notopterygium, angelica dahurica, Chuanwu, Aconitum, Tianxianteng, Chuanxuduan, Sanguisorba officinalis, Phellodendron chinense, Viscum album, Eucommia ulmoides, cat's claw, Smilax glabra and licorice is 6:6:6:6:6:6:5:5:5:5:4:4:4:4:3; the ratio of the traditional Chinese medicine composition to water is between 1:6 and 1:7.
[0010] Preferably, the water boiling step adopts the above-mentioned proportion to boil over high heat, simmer for 15-18 minutes, and filter the medicinal liquid to make the first decocted medicinal liquid; continue to add water according to the above-mentioned proportion, boil over high heat for the second time, and simmer for 18-20 minutes to make the second decocted medicinal liquid;
[0011] The first decoction liquid is mixed with the second decoction liquid to obtain the finished Chinese medicine liquid, which is then cooled for later use.
[0012] Step 2. Paper preparation
[0013] 1. Take mulberry bark as the main raw material, soak it in water, boil it with ash, steam it with alkali, and sieve it to get the skin pulp;
[0014] The rice straw is threshed, soaked in ash, boiled, and sieved to obtain straw slurry;
[0015] Paper pulp is made by mixing skin pulp and straw pulp.
[0016] 2. Boil the water and let it cool, mix it with the Chinese medicine solution prepared in step 1 at a ratio of 1:1 to 1:1.2 and pour it into the paper trough;
[0017] Pour the pulp into the paper trough and use the paper curtain to scoop out the paper;
[0018] The ratio of the mixed liquid of water and traditional Chinese medicine liquid to paper pulp is 1:20-25.
[0019] drying;
[0020] 3. Spray the drying paper to rehydrate it in the form of a spray, wherein the liquid used for the spray is the Chinese medicinal liquid prepared in step 1;
[0021] 4. Dry and cut to obtain finished paper.
[0022] Example 1: The Chinese medicinal rice paper with therapeutic effects is crushed and used as a content to wrap the Chinese medicinal rice paper to prepare a moxibustion stick.
[0023] Preferably, the dried and cut rice paper edges are used for crushing and making moxibustion sticks.
[0024] Example 2: The Chinese medicinal rice paper with physiotherapy effect is used as moxibustion stick packaging paper.
[0025] Example 3: The Chinese medicine rice paper with physiotherapy effect is sealed and packaged with Chinese medicine liquid. The Chinese medicine liquid refers to the Chinese medicine liquid prepared in step 1. The effect achieved by this is that the packaged content is directly used as moxibustion mud, or used as a mud pad paper to fit the surface of human skin in combination with moxibustion methods such as ginger moxibustion.
[0026] Example 4: The Chinese medicinal rice paper with physical therapy effect is cut into rectangular paper pieces, sealed and packaged, and used as hot compress pad paper.
[0027] Example 5: The Chinese medicinal rice paper with physiotherapy effect is crushed and mixed with Chinese medicinal liquid to prepare Du-moxibustion mud; the ratio of solid matter to Chinese medicinal liquid in the Du-moxibustion mud is 1:08-0.9.
[0028] The beneficial effects of the present invention are as follows: the present invention fills a gap in the market, prepares Chinese medicine liquid by mutual verification of contemporary medical technology and traditional Chinese medicine, and combines the water absorption characteristics of traditional rice paper, and the finished rice paper prepared has a positive effect of promoting the curative effect in the process of physical therapy. It is particularly suitable for the use of Du moxibustion by people with yang deficiency constitution who have cold limbs, cold accumulation in the body, and are prone to fatigue and fatigue. On the basis of the effects of traditional moxibustion warming yang and unblocking meridians, promoting blood circulation and removing blood stasis, and lifting yang, it can also relieve the cold, dispel wind and overcome dampness, nourish the liver and kidney, strengthen the tendons and bones, and stop arthralgia, and achieve the purpose of warming the kidney and unblocking Du, balancing yin and yang, and keeping the body healthy with the physiotherapy effects of related drugs. And the product is easy to use after packaging, especially when used as a Du moxibustion patch, it has better curative effect than the mulberry paper patch in the prior art, and has more medical promotion value.
[0029] The realization of the purpose, functional features and advantages of the present invention will be further explained in conjunction with embodiments. DETAILED DESCRIPTION
[0030] Preparation steps:
[0031] The method for preparing the Chinese medicinal rice paper with therapeutic effect comprises the following steps:
[0032] Step 1. Preparation of Chinese medicine solution
[0033] 1. Use mugwort leaves, ginger, angelica root, angelica pubescens, Chuanwu, Caowu, Tianxianteng, Chuanxuduan, Sanguisorba officinalis, Pteris cretica, Viscum album, Eucommia bark, Cat's Claw, Rhizoma Smilacis Glabrae, and licorice as traditional Chinese medicine, boil them in water, filter the residue, and make a traditional Chinese medicine liquid for later use.
[0034] Preferably, the ratio of the above-mentioned traditional Chinese medicine composition and water is as follows: the ratio of mugwort, ginger, notopterygium, angelica dahurica, Chuanwu, Aconitum, Tianxianteng, Chuanxuduan, Sanguisorba officinalis, Phellodendron chinense, Viscum album, Eucommia ulmoides, cat's claw, Smilax glabra and licorice is 6:6:6:6:6:6:5:5:5:5:4:4:4:4:3; the ratio of the traditional Chinese medicine composition to water is between 1:6 and 1:7.
[0035] Preferably, the water boiling step adopts the above-mentioned proportion to boil over high heat, simmer for 15-18 minutes, and filter the medicinal liquid to make the first decocted medicinal liquid; continue to add water according to the above-mentioned proportion, boil over high heat for the second time, and simmer for 18-20 minutes to make the second decocted medicinal liquid;
[0036] The first decoction liquid is mixed with the second decoction liquid to obtain the finished Chinese medicine liquid, which is then cooled for later use.
[0037] Step 2. Paper preparation
[0038] 1. Take mulberry bark as the main raw material, soak it in water, boil it with ash, steam it with alkali, and sieve it to get the skin pulp;
[0039] The rice straw is threshed, soaked in ash, boiled, and sieved to obtain straw slurry;
[0040] Paper pulp is made by mixing skin pulp and straw pulp.
[0041] The above pulp preparation steps are the preparation steps of ordinary rice paper pulp in the prior art, and the specific proportions thereof are not repeated here.
[0042] 2. Boil the water and let it cool, mix it with the Chinese medicine solution prepared in step 1 at a ratio of 1:1 to 1:1.2 and pour it into the paper trough;
[0043] Pour the pulp into the paper trough and use the paper curtain to scoop out the paper;
[0044] The ratio of the mixed liquid of water and traditional Chinese medicine liquid to paper pulp is 1:20-25.
[0045] drying;
[0046] 3. Spray the drying paper to rehydrate it in the form of a spray, wherein the liquid used for the spray is the Chinese medicinal liquid prepared in step 1;
[0047] 4. Dry and cut to obtain finished paper.
[0048] Solution:
[0049] In the prescription, mugwort warms the meridians and stops bleeding, dispels cold and relieves pain; it can be used externally to dispel dampness and relieve itching. Ginger relieves the exterior and dispels cold. Notopterygium root relieves the exterior and dispels cold, dispels wind and overcomes dampness, and relieves pain. This product is pungent and dispels wind, bitter and damp, warm and dispels cold, and is commonly used to treat rheumatic arthralgia, and is good at treating rheumatism in the upper part. Duhuo is good at dispelling rheumatism in the lower part, and combined use can dispel rheumatism from top to bottom of the body, clear the joints and relieve pain. Chuanwu and Caowu have the effects of dispelling wind and dampness, warming the meridians and relieving pain, and are used for wind-cold-damp arthralgia, joint pain, cold pain in the heart and abdomen, pain caused by cold hernia, and anesthesia and pain relief. Ancient prescriptions are also often used as anesthetic analgesics, and are all monarch drugs.
[0050] Tianxianteng promotes qi and blood circulation, dredges meridians and relieves pain. It can treat abdominal pain caused by qi stagnation and blood stasis, rheumatic pain, etc. It can treat rheumatic pain and accumulation of masses. Chuanxuduan has the effects of nourishing the liver and kidney, nourishing tendons and bones, calming the fetus and stopping bleeding. It can not only nourish the liver and kidney, but also promote blood circulation, and at the same time nourish without stagnation. It can treat symptoms such as weakness of the limbs, soreness of the waist and knees caused by liver and kidney deficiency. Xuejie promotes blood circulation and relieves pain, removes blood stasis and stops bleeding, astringes sores and promotes tissue regeneration. It tastes sweet and salty, is flat in nature, and belongs to the liver meridian. Xuejie enters the blood and disperses blood stasis and relieves pain. It is an important medicine for trauma and other stasis pain syndromes. Guijianyu has the effects of breaking blood and detoxifying, eliminating swelling and pain, and killing insects. It is compatible with kidney-tonifying and blood-removing, heat-clearing and dampness-clearing drugs. It has the effects of resisting bacteria and viruses, improving immunity, and improving kidney function. It treats postpartum stasis abdominal pain, worm accumulation abdominal pain, urinary tract infection, etc., and is a minister drug.
[0051] Mulberry parasite and Eucommia bark benefit the liver and kidney, dispel rheumatism, and strengthen the tendons and bones. Cat's scratch grass has the effects of promoting blood circulation and removing blood stasis, reducing swelling and dispersing knots. Rhizoma Lulutong has the effects of dispelling wind and activating collaterals, promoting diuresis, promoting menstruation and lactation, and relieving itching. "Supplement to Compendium of Materia Medica": It can relieve spasms in the meridians, pain in the whole body, pain in the hands, feet and waist. They are both adjuvants. Licorice harmonizes the various drugs.
[0052] Modern medical research results confirm
[0053] Artemisia argyi Lévl.et.Vant. is a dried leaf of the Asteraceae plant Artemisia argyi Lévl.et.Vant. It is also known as ice platform, medicinal grass, moxibustion grass, etc. It is a traditional Chinese medicine with a long history of application. Artemisia argyi tastes bitter and pungent, is warm in nature, and belongs to the liver, spleen, and kidney meridians. "Compendium of Materia Medica" says: "Warms the middle, drives away cold, and removes dampness." It mainly contains volatile oils, flavonoids, phenylpropanoids, terpenes and other ingredients, and has multiple pharmacological effects such as antibacterial, antiviral, hemostatic, anti-tumor, liver protection, analgesic, anti-inflammatory, antioxidant, and antitussive and antiasthmatic. In traditional Chinese medicine, moxibustion has the functions of disease prevention and health care, warming meridians and dispersing cold, restoring yang and consolidating deficiency, raising yang and lifting sunken, promoting blood circulation and qi, eliminating stasis and dispersing knots, etc. Modern pharmacology shows that it also has multiple pharmacological effects such as local injury stimulation, regulating neuroendocrine immune network, regulating body metabolism, regulating immune function, and improving blood circulation, so it is used in the treatment of inflammation, tumors, cognitive impairment in the elderly, depression, colitis, frequent urination, hyperlipidemia, hypertension and other diseases, that is, moxibustion cures all diseases. Notopterygium is the rhizome and root of Notopterygium or Notopterygium of the Umbelliferae plant. It tastes spicy and bitter, and is warm in nature. It belongs to the bladder and kidney meridians. Notopterygium has obvious antipyretic, analgesic, anti-inflammatory, and anti-allergic effects. Its analgesic active ingredients include pursiculatin and notopterygium alcohol, which provide a certain pharmacological basis for the clinical application of Notopterygium to treat wind-cold dampness arthralgia and joint pain.
[0054] Ginger is the fresh rhizome of the perennial herbaceous plant Zingiber officinale. It is pungent and slightly warm in nature. It enters the lung, spleen and stomach meridians. It can dispel cold, warm the middle and stop vomiting, warm the lungs and stop coughing, and detoxify. Ginger has multiple pharmacological effects such as antibacterial, anti-inflammatory, analgesic, and antioxidant. Its extract has a significant inhibitory effect on Staphylococcus aureus, Staphylococcus albus, Salmonella typhi, Shigella sonnei, and Pseudomonas aeruginosa, and can be used to treat schistosomiasis. Ginger juice can inhibit the growth of cancer cells to a certain extent. Adding ginger extract to some anti-tumor drugs can reduce the side effects of tumor drugs without obvious toxicity.
[0055] Duhuo is the dried root of the Umbelliferae plant Angelica sinensis. It tastes bitter, pungent, and slightly moist. It enters the kidney and bladder meridians. It was first recorded in Shennong's Herbal Classic. Benjing Fengyuan said: "It is forbidden to use it for those with qi and blood deficiency, body pain, and yin deficiency and lower body weakness. All types of wind deficiency are not suitable for Duhuo." Ancient records show that Duhuo can disperse the latent wind in the body, remove dampness and relieve pain, and treat wind-cold and dampness. Because it enters the kidney meridian, and the kidney governs the waist and knees, it mainly treats the waist and lower limbs. It is good at removing the symptoms of the lower jiao caused by wind, cold and dampness between the waist and knees, such as waist and knee pain, foot pain, and toe swelling. Modern pharmacological studies have shown that Duhuo has anti-inflammatory, sedative, analgesic, hypnotic, antihypertensive, anti-arrhythmic, anticoagulant, and anti-tumor pharmacological activities.
[0056] Chuanwu is an annual herbaceous plant of the Ranunculaceae family. The root tuber is yellow in texture, spindle-shaped or ovate, with a dark brown outer skin and many fibrous roots at the bottom. It was first recorded in Shennong's Herbal Classic and listed as a medium-grade product. It has a good effect in treating rheumatoid arthritis. Modern pharmacology has found that it also has anti-tumor effects. It is a commonly used Chinese medicine in clinical practice. It has the effects of dispelling wind and dampness, warming the meridians and relieving pain. It is used for wind-cold dampness, joint pain, cold pain in the heart and abdomen, pain caused by cold hernia, and anesthesia and analgesia. It has a long history of medicinal use and high medicinal value. Modern pharmacological studies have shown that Chuanwu has a good therapeutic effect on rheumatoid arthritis, neuropathic pain, hypertension and other diseases. As a famous toxic Chinese medicine, Chuanwu's main medicinal and toxic components are alkaloid components. While exerting anti-inflammatory, analgesic, anti-tumor and other medicinal effects, it can also cause neurotoxicity and cardiotoxicity. Therefore, its toxicity is often reduced by processing during clinical use. Total alkaloids of Aconiti chuanxiong can significantly reduce the content of prostaglandin E (PGE) in carrageenan exudates, indicating that inhibition of PCE may be one of its anti-inflammatory mechanisms.
[0057] Aconitum kusnezoffii is the dried root of the Ranunculaceae plant Aconitum kusnezoffii. It is bitter, hot, highly toxic, and enters the heart, liver, kidney, and spleen meridians. It has the functions of dispelling wind and dampness, warming the meridians and relieving pain. It is used for wind-cold dampness arthralgia, cold pain in the heart and abdomen, anesthesia and pain relief, etc. It is a commonly used precious Chinese medicine and Mongolian medicinal material in clinical practice. Modern pharmacological studies have shown that Aconitum kusnezoffii has analgesic, anti-inflammatory, anti-tumor and cardiotonic effects, and also has immune, antioxidant, anti-aging and other functions. The diterpene alkaloids in its alkaloid components are the key components to exert therapeutic effects. It is used to treat cold and damp blood stasis in the meridians, spasm and pain in the tendons and veins of the limbs, and poor flexion and extension of the joints: it is used together with Chuanwu, earthworms, frankincense, etc. ("Hejijufang").
[0058] Tianxianteng is the dried aerial part of Aristolochia debiLis Sieb.etZucc. or AristoLochia contorta Bge. of the Aristolochiaceae family. It is harvested in autumn, impurities are removed, and it is dried in the sun. It tastes bitter and is warm and mild in nature. It can prevent water from hurting hands, clear the wind and relieve summer heat, and has the effects of invigorating qi, dispelling wind and removing dampness, and clearing water and removing dampness. It can be used for hernia, joint pain, pregnancy edema and other diseases, and can relieve pain, cough, antibacterial, and promote qi and eliminate dampness.
[0059] Dipsacus asper Wall.ex Henry is a perennial herbaceous plant of the Dipsacus family. It is bitter, sweet, pungent, and slightly warm in nature, and belongs to the liver and kidney meridians. It has the effects of nourishing the liver and kidney, strengthening tendons and bones, healing fractures, and stopping bleeding and stabilizing pregnancy. It is mainly used to treat liver and kidney deficiency, soreness of the waist and knees, cold and dampness arthralgia, metrorrhagia, fetal movement disorder, traumatic injury, tendon and bone fracture, etc. Modern pharmacological studies have found that Dipsacus asper has the effect of inhibiting uterine muscle contraction; it has an inhibitory effect on Streptococcus pneumoniae and can kill Trichomonas vaginalis; it has the effects of pus discharge, hemostasis, analgesia, and promoting tissue regeneration for carbuncle; the decoction has a promoting effect on bone injury healing, and the effect increases with the increase of dosage. Total saponins are the active ingredients that promote the healing of bone injuries. In addition, Dipsacus asper also has the effect of resisting vitamin E deficiency.
[0060] Dragon's blood is made from the resin exuded from the fruit of the palm plant Qilinjie. It is sweet, smooth and neutral in nature. Efficacy: promoting blood circulation and dispersing blood stasis, stopping bleeding, relieving pain and promoting tissue regeneration. It is mainly used to treat injuries caused by falls, wounds, blood stasis and pain, and ulcers that are difficult to heal. It mainly contains resin and volatile oil, as well as plant residues, hepcol and other ingredients. Anti-inflammatory: It can antagonize the inflammation of the mouse ear caused by xylene, accelerate the formation of inflammation caused by burns, and promote wound healing. Antithrombotic: This product has a very obvious anti-thrombotic effect. It can promote the dissolving activity of fibrinolytic enzymes. However, it has no effect on the coagulation time, prothrombin time and blood viscosity of rabbits. Increase coronary flow: This product can excite β-receptors and increase the coronary flow of rabbits. Dragon's blood can increase the content of cAMP and reduce the level of cGMP. This effect is related to the excitation of β-receptors, not the effect of M-receptors. It can shorten the plasma recalcification time of rabbits and has a strong inhibitory effect on a variety of pathogenic bacteria and fungi.
[0061] Ghost arrow feather is a winged branch or wing-like appendage of Euonymusalatus (Thunb.) Sieb. of the Celastraceae family. It tastes bitter, pungent, cold and non-toxic. It can break blood and promote menstruation, detoxify and reduce swelling, and kill insects. It is mainly used to treat lumps, heart and abdominal pain, amenorrhea, dysmenorrhea, metrorrhagia, abdominal pain caused by stasis after childbirth, lochia retention, hernia, rheumatic pain, sores, injuries from falls, abdominal pain caused by insect accumulation, burns, and snake bites. ① Breaking blood and promoting menstruation: Ghost arrow feather mainly has the medicinal effect of promoting blood circulation and dissipating blood stasis, especially the effect of promoting blood circulation and removing blood stasis is particularly strong, which can help break blood and promote menstruation, so it is often used to regulate some gynecological diseases. If a woman has symptoms of irregular menstruation such as amenorrhea and dysmenorrhea, or has symptoms such as stasis abdominal pain and lochia retention after childbirth, she can take ghost arrow feather for treatment. ② Detoxification and swelling: Ghost arrow feather can play a more significant detoxification and swelling effect, can attack poison and treat sores, and can avoid plague evil spirits. It has a therapeutic effect on injuries and burns caused by falls, and can also be used as a therapeutic drug for snake bites, rabies injuries, and animal bites. ③ Insecticide and deworming: After studying the drug components of ghost arrow feather, it was found that it has a very obvious killing, paralysis and stimulating effect on intestinal parasites, which can promote the excretion of parasites from the body and play a deworming and deworming role. Therefore, it can help treat abdominal pain caused by worm accumulation, intestinal parasitic diseases, and other diseases caused by parasitic infections. ④ Regulating blood lipids: Ghost arrow feather can help regulate blood lipid levels, and can effectively reduce the cholesterol content in the blood and the total cholesterol value in plasma. In addition, taking this kind of medicine can also increase the transfer capacity of lecithin and cholesterol acyl transfer, prevent the occurrence of abnormal lipid metabolism, and thus prevent and treat atherosclerosis. ⑤ Lower blood sugar: Ghost arrow feather contains a certain amount of effective ingredients such as sodium acetyl oxalate, which can increase the proliferation of pancreatic β-cells and help promote the secretion of insulin, thus helping to lower blood sugar. ⑥ Strengthen the heart and expand the coronary artery: Ghost arrow feather has the effect of strengthening the heart and expanding the coronary artery, which can directly act on myocardial cells and expand the coronary artery, and can effectively reduce the possibility of coronary heart disease and myocarditis.
[0062] Mulberry is the leaves and branches of the plant Morus alba of the Morus alba family. It tastes bitter and sweet, and is neutral. It enters the liver and kidney meridians. According to the Compendium of Materia Medica, Mulberry has the functions of removing rheumatism, nourishing the liver and kidney, strengthening the tendons and bones, and calming the fetus and promoting lactation. It is used for rheumatic pain, soreness of the waist and knees, hypertension, restless fetuses, and postpartum milk deficiency. It can be used in tumor treatment as an immunostimulant to promote cell division to control and adjust the immune system. Inhibition of platelet aggregation: In vivo injection of 4mg / kg of total glycosides can significantly inhibit the MDA produced after AA-Na conversion metabolism. When the MDA content decreases, the optical density value decreases significantly, and the intensity of action is similar to that of acetylsalicylic acid.
[0063] Eucommia ulmoides is the dried bark of Eucommia ulmoides, a plant of the Eucommia family. The inner surface is dark purple, smooth, brittle and easy to break, and the cross section is connected by fine, silvery white, elastic rubber threads. It has a slight odor and a slightly bitter taste. It has the effects of nourishing the liver and kidneys, strengthening the bones and muscles, and calming the fetus. Eucommia ulmoides is rich in a variety of active ingredients such as iridoids, lignans, flavonoids, phenylpropanoids, polysaccharides, etc. It has significant advantages in lowering blood pressure, lowering blood lipids, lowering blood sugar, preventing osteoporosis, anti-oxidation, and immune regulation.
[0064] Cat's claw is a perennial herb of the genus Ranunculaceae. The tuberous roots grow in clusters, are nearly spindle-shaped or nearly oblong, fleshy, and aggregated in the shape of a cat's claw. The stem height is 5 to 17 cm. It is sweet, pungent, and warm in nature. Modern pharmacological experiments have shown that the drug can not only inhibit the growth of tuberculosis bacteria, but also improve the body's immunity, enhance the bactericidal effect of the drug, slow down the production of drug-resistant bacteria, and improve the efficacy. It is not easy to develop drug resistance. Its active ingredients have an inducing effect on tumor necrosis factor and have a stasis-removing and swelling-reducing effect on swollen lymph nodes. It can promote the absorption and dissipation of sheep red blood cells, improve blood circulation around lymph node tuberculosis lesions, and make it easier for drugs to penetrate into tissues.
[0065] Lulutong is the dried mature infructescence of Liquidambar formosanaHance, a plant of the Hamamelidaceae family. The fruits are harvested in winter after they mature, impurities are removed, and they are dried. They are bitter and neutral in nature. They enter the liver and kidney meridians. The main ingredients, betulinic acid (also known as Lulutong acid) and gallic acid, can exert anti-inflammatory effects by reducing capillary permeability, inhibiting the secretion of inflammatory mediators, and participating in the NF-KB signaling pathway. Betulinic acid and gallic acid have certain inhibitory effects on viruses, bacteria and fungi, and Lulutong volatile oil has certain antibacterial effects on various bacteria such as Staphylococcus aureus. Gallic acid in Lulutong exerts a neuroprotective effect by maintaining calcium homeostasis and nourishing nerve cells. Lulutong injection can significantly inhibit the occurrence of cerebral edema. Gallic acid exerts an antioxidant effect by reducing the oxidation reaction of tissue cells and increasing the affinity with free radicals. Betulinic acid has cytotoxicity to cancer cells and can induce endogenous apoptosis of solid tumors. It exerts an anti-tumor effect by participating in the division and proliferation of tumor cells.
[0066] Licorice is a perennial herbaceous plant of the genus Glycyrrhiza in the Leguminosae family. It tastes sweet and is neutral in nature. It enters the heart, lung, spleen, and stomach meridians. It nourishes the spleen and replenishes qi, clears away heat and detoxifies, eliminates phlegm and relieves cough, relieves pain, and harmonizes various medicines. It is used for spleen and stomach weakness, fatigue, palpitations and shortness of breath, cough with sputum, abdominal and limb cramps and pain, carbuncle, sore, and relieves drug toxicity and potency. It should not be used with seaweed, Euphorbia jing, Euphorbia rubrum, Ginseng, and Daphne. The main chemical components are flavonoids, saponins, coumarins, polysaccharides and other compounds, and its active ingredients have multiple pharmacological effects such as anti-tumor, anti-inflammatory, antiviral, and liver protection.
[0067] Example:
[0068] Example 1: The Chinese medicinal rice paper with therapeutic effects is crushed and used as a content to wrap the Chinese medicinal rice paper to prepare a moxibustion stick.
[0069] Preferably, the dried and cut edges of the Chinese medicinal rice paper are used for crushing and making moxibustion sticks.
[0070] Example 2: The Chinese medicinal rice paper with physiotherapy effect is used as moxibustion stick packaging paper.
[0071] Embodiment 3: The Chinese medicine with physiotherapy effect is sealed in rice paper, and Chinese medicine liquid is encapsulated in the package;
[0072] The Chinese medicine liquid refers to the Chinese medicine liquid prepared in step 1, and the mass ratio of paper to the Chinese medicine liquid is 1:1.4.
[0073] Preferably, the Chinese herbal medicine liquid and the Chinese herbal rice paper are packaged separately, that is, the Chinese herbal medicine liquid is packaged independently and sealed with the Chinese herbal rice paper.
[0074] The effect achieved by this is that the packaged contents are crushed and used directly as moxibustion mud, or used as mud pad paper to fit the surface of human skin in combination with moxibustion methods such as ginger moxibustion.
[0075] Embodiment 4: The Chinese medicinal rice paper with physical therapy effect is cut into rectangular paper pieces and sealed and packaged, and used as hot compress pad paper.
[0076] Example 5: The Chinese medicinal rice paper with physiotherapy effect is crushed and mixed with Chinese medicinal liquid to prepare Du-moxibustion mud; the ratio of solid matter to Chinese medicinal liquid in the Du-moxibustion mud is 1:08-0.9.
[0077] Preferably, the moxibustion mud is prepared by using the edges and corners of traditional Chinese medicine rice paper that have been dried and cut. Experimental data:
[0078] Source of research subjects and sample size:
[0079] Study subjects: Yang deficiency patients in the Center for Preventive Treatment of Diseases of the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine from June 2022 to December 2022. Sample size estimation: According to the formula N = 2*[(α+β)×σ / δ] 2 , the minimum sample size required was estimated to be 60 cases, and a total of 60 patients were included in this experiment.
[0080] Western medicine diagnostic criteria
[0081] With reference to the "Sub-health Chinese Medicine Clinical Guidelines" issued by the China Association of Traditional Chinese Medicine in 2006, the following is formulated:
[0082] (1) In terms of physical health, the main manifestations are fatigue without any cause, frequent decline in sleep quality, or varying degrees of body pain;
[0083] (2) Mental health is mainly manifested by symptoms such as frequent anxiety, depression, irritability, fear, memory loss, difficulty concentrating, and even suicidal thoughts;
[0084] (3) Social health is mainly manifested by decreased social adaptability, such as unwillingness to communicate with others and poor interpersonal relationships;
[0085] Any of the above three items must last for at least 3 months, and other diseases must be excluded.
[0086] TCM diagnostic criteria
[0087] The Yang deficiency constitution is formulated as follows with reference to the Classification of 9 Basic TCM Constitution Types and Their Diagnostic Expression Basis:
[0088] Main symptoms: ① Usually afraid of cold, cold hands and feet; ② Lack of energy, excessive sleep; ③ Like hot food; ④ Pale, plump and tender tongue with teeth marks on the edges and moist tongue coating; ⑤ Slow and weak pulse.
[0089] Secondary symptoms: ① easy sweating; ② soft and pale complexion, or dark eyelids, or pale lips; ③ easy hair loss; ④ clear and long urine; ⑤ loose and thin stools.
[0090] Determination of syndrome type: Yang deficiency constitution can be diagnosed only when 2 main symptoms (fear of cold, cold hands and feet are essential) plus 2 secondary symptoms, or 1 main symptom plus 3 secondary symptoms are present.
[0091] Inclusion criteria
[0092] ① Select a reasonable age range. This study selected patients between 20 and 60 years old, regardless of gender; ② Patients who meet the diagnostic criteria for sub-health; ③ Patients who meet the diagnostic criteria for TCM syndromes of yang deficiency constitution; ④ Those who have not received treatment for the disease in the past six months; ⑤ The patients signed an informed consent form.
[0093] Exclusion criteria
[0094] ① Those who are allergic to moxibustion and topical medications; ② Those who suffer from severe cardiovascular and cerebrovascular diseases, chronic diseases such as hypertension, diabetes, blood system diseases, etc.; ③ Those with severe mental illnesses; ④ Women during menstruation and pregnancy; ⑤ Those who are not suitable for this treatment method, such as those who cannot lie prone for a long time, or those with trauma to the treatment area and unhealed skin damage.
[0095] Note: If any one of the above criteria is met, it will be excluded.
[0096] Elimination criteria
[0097] ① Patients who were improperly selected or found not to meet the inclusion criteria after inclusion; ② Patients with poor compliance or who received other treatments during the treatment process, which affected this study; ③ Patients who experienced serious adverse events during the treatment process and were diagnosed and judged by the subject researchers that they should not continue the treatment.
[0098] Note: Those who meet any one of the criteria should be excluded from this study.
[0099] Shedding standard
[0100] ① Those who left the group without doctor's advice; ② Those who were lost to follow-up or withdrew from treatment despite dissuasion due to personal reasons.
[0101] Note: Those who meet any one of the criteria are considered to be out of the study.
[0102] Research Methods
[0103] Grouping and randomization methods
[0104] During the research of this subject, 60 patients were recruited and the random number table method was used.
[0105] (1) 60 subject numbers were prepared in advance; (2) random numbers were generated; (3) those with odd numbers were assigned to Group A, and those with even numbers were assigned to Group B; when one group met the number of cases, the rest were assigned to the other group; (4) Group A served as the observation group (treatment with Chinese herbal xuan paper as the moxibustion mud pad, hereinafter referred to as the Chinese herbal xuan paper moxibustion group), and Group B served as the control group (traditional moxibustion treatment, i.e., mulberry bark paper as the moxibustion mud pad, hereinafter referred to as the moxibustion group), with 30 cases in each group.
[0106] Blind method
[0107] The letters A and B are used to replace the grouping to ensure that the data analysts cannot determine which intervention the patients received.
[0108] Handling of dropout cases
[0109] When a case drops out, follow-up visits should be conducted according to the case information to communicate with the dropped out patient in a timely manner, and the reasons for the dropout should be recorded in detail. Patients with unknown reasons and those who cannot be contacted should all be included in the dropout observation record.
[0110] Treatment
[0111] The diet is mainly light vegetarian, and eat more plant protein, such as soybeans, peanuts, green vegetables, etc. Avoid eating fishy, mutton, spicy, sweet, greasy, thick and cold foods, such as alcohol, aquatic products, mutton, chicken, dog meat, cucumbers, leeks, coriander, peppers, etc.
[0112] 1. Chinese medicine Xuan paper moxibustion group:
[0113] ①Material preparation: traditional moxibustion sticks with moxa as the content are used as moxibustion sticks;
[0114] The Chinese medicine rice paper prepared in Example 3 is used as a support for ginger paste and fixed on the patient's Du channel;
[0115] Ginger paste: Prepare 5 catties of ginger, wash and cut into small pieces, put into a blender, and blend the ginger without any grains. The required moisture of the ginger paste should be firm but not cracked, moist but without juice.
[0116] Moxa cone: The moxa cone should be firm and spindle-shaped, about 7 cm long and 1 cm in diameter.
[0117] Operation method: ① The patient wears the moxibustion suit, exposes the back, and lies prone. The doctor uses his fingernails to press the mark from the Dazhui to the spinous process of the Yaoshu segment;
[0118] ② Use 75% alcohol cotton balls to disinfect from Dazhui to Yaoshu for 3 times, and use the wet Chinese medicine rice paper prepared in Example 3 as a support for ginger paste to fix it on the patient's Du channel;
[0119] ③ Spread the ginger paste evenly on the Chinese medicine rice paper, and pile it into a trapezoid with the same length from Dazhui to Yaoshu, about 4cm wide at the upper bottom, 6cm wide at the lower bottom, and 3cm high. Use a tongue depressor to compact the ginger paste into a trapezoid, making sure it is tight but not cracked. Press a groove about 0.5cm wide and 0.5cm deep in the middle of the upper surface of the ginger paste. Finally, place a spindle-shaped moxa cone on the ginger paste, connecting the ends and compacting it in the groove.
[0120] ④ Place the rubbed moxa cones end to end, place them in the groove, and light them at the midpoint and 1 / 3 of the top and bottom. After burning one cone, continue to place them for a total of 3 cones. When all of them are burned, the researchers clean the back with a warm towel, cover the moxibustion suit, and gather the qi for a while. This operation takes about 90 minutes. The above treatment method is once a week, one course of treatment is 4 weeks, and a total of 2 courses of treatment.
[0121] 2. Governor-moxibustion group
[0122] ①Material preparation: traditional moxibustion sticks with moxa as the content are used as moxibustion sticks;
[0123] Mulberry paper;
[0124] Ginger paste: Prepare 5 catties of ginger, wash and cut into small pieces, put into a blender, and blend the ginger without any grains. The required moisture of the ginger paste should be firm but not cracked, moist but without juice.
[0125] Moxa cone: The moxa cone should be firm and spindle-shaped, about 7 cm long and 1 cm in diameter.
[0126] Operation method: ① The patient wears the moxibustion suit, exposes the back, and lies prone. The doctor uses his fingernails to press the mark from the Dazhui to the spinous process of the Yaoshu segment;
[0127] ②Use 75% alcohol cotton balls to disinfect from Dazhui to Yaoshu three times, soak mulberry paper as a support for ginger paste and stick it on the patient's Du channel to fix it;
[0128] ③ Spread the ginger paste evenly on the mulberry paper, and pile it into a trapezoid with the same length from Dazhui to Yaoshu, about 4cm wide at the upper bottom, 6cm wide at the lower bottom, and 3cm high. Use a tongue depressor to compact the ginger paste into a trapezoid, making sure it is firm but not cracked. Press a groove about 0.5cm wide and 0.5cm deep in the middle of the upper surface of the ginger paste. Finally, place a spindle-shaped moxa cone on the ginger paste, connecting the ends and compacting it in the groove.
[0129] ④ Place the rubbed moxa cones end to end, place them in the groove, and light them at the midpoint and 1 / 3 of the top and bottom. After burning one cone, continue to place them for a total of 3 cones. When all of them are burned, the researchers clean the back with a warm towel, cover the moxibustion suit, and gather the qi for a while. This operation takes about 90 minutes. The above treatment method is once a week, one course of treatment is 4 weeks, and a total of 2 courses of treatment.
[0130] Clinical observation indicators
[0131] The following indicators were observed 1 day before the start of treatment and on the day after the end of 2 courses of treatment.
[0132] 1. Single-item scoring of yang deficiency constitution symptoms and final conversion score: Refer to the "Classification and Determination of Chinese Medicine Constitution" standard promulgated in 2009 [, and answer all the questions in the yang deficiency constitution determination scale (see Appendix A for details). Each item is scored 1, 2, 3, 4, and 5 points according to "never (or) not", "rarely", "sometimes", "often", and "always". The conversion score is calculated as follows: first, add the scores of each item to get the original score; conversion score = (original score-7) / 28×100. According to the calculated scoring results, if the yang deficiency constitution conversion score is ≥40 points, it can be determined as yang deficiency constitution, and the higher the score, the more obvious the symptoms of yang deficiency constitution.
[0133] 2. Fatigue scale score: Use the internationally recognized "Fatigue Scale SF-14". Add the scores of items 1 to 8 to get the physical fatigue score, and add the scores of items 9 to 14 to get the mental fatigue score. The total fatigue score is the sum of the physical and mental fatigue scores. The highest physical fatigue score is 8, the highest mental fatigue score is 6, and the highest total score is 14. The higher the score, the more severe the fatigue. (See Appendix B for details)
[0134] Efficacy determination
[0135] The efficacy evaluation standard refers to the standard for determining biased constitution in the "Classification and Determination of Constitution in Traditional Chinese Medicine" issued by the Chinese Association of Traditional Chinese Medicine in 2009:
[0136] 1. Markedly effective: conversion score <30 points, Yang deficiency constitution is judged as “no”;
[0137] 2. Effective: After treatment, the conversion score is between 30 and 39 points, and Yang deficiency is judged as "tendency to be yes";
[0138] 3. Invalid: The conversion score is still greater than 40 points, and Yang deficiency is judged as “yes”.
[0139] Total effective rate = (number of markedly effective cases + number of effective cases) / total number of cases × 100%.
[0140] Safety observation
[0141] Observe whether there are any adverse reactions after Chinese medicine Xuan paper moxibustion and moxibustion treatment, and promptly handle and record the occurrence, end, outcome, reaction characteristics, degree, treatment method, and whether to withdraw from the trial.
[0142] Statistical processing methods
[0143] All data before and after treatment were recorded and imported into the database, and analyzed using SPSS26.0 statistical software. All measurement data were first tested for normality. The data that met the normal distribution were tested using the t test, and the data that did not meet the normal distribution were tested using the rank sum test. Indicates; rank sum test is used for rank data, and X 2 P>0.05 means no statistical significance, P<0.05 means there is a significant difference.
[0144] Analysis of research results
[0145] General Information
[0146] All patients were from the Yang Deficiency Center of the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine from June 2022 to December 2022, with a total of 60 cases, 30 cases in the Chinese medicine Xuan paper group and 30 cases in the Governor-moxibustion group. No cases dropped out during the treatment in both groups. Among them, there were 15 males and 15 females in the Chinese medicine Xuan paper Governor-moxibustion group, with an average age of (38.43±10.46) years old; there were 14 males and 16 females in the Governor-moxibustion group, with an average age of (40.26±7.36) years old; there was no statistical difference (P>0.05) in gender (P=0.615), age (P=0.436), and course of disease (P=0.399) between the two groups before treatment, and they were comparable. (See Tables 1, 2, and 3)
[0147] Table 1 Comparison of gender between the two groups of patients
[0148]
[0149] Table 2 Comparison of age between the two groups of patients
[0150]
[0151] Table 3 Comparison of disease course between the two groups
[0152]
[0153] The symptom scores of yang deficiency constitution were compared between the two groups of patients before treatment. Independent sample T test was used. The results were all P>0.05, with no statistically significant difference and comparable, as shown in Table 4.
[0154] Table 4 Comparison of symptom scores of Yang deficiency constitution between the two groups of patients before treatment ( point)
[0155]
[0156]
[0157] The comparison of the yang deficiency constitution conversion scores between the two groups of patients before treatment was performed using the independent sample T test. The comparison of the yang deficiency constitution conversion scores between the two groups of patients before treatment was P>0.05, with no statistically significant difference, and they were comparable, see Table 5
[0158] Table 5 Comparison of Yang deficiency constitution transformation scores between the two groups of patients before treatment ( point)
[0159]
[0160] The fatigue scale scores of the two groups of patients before treatment were compared by independent sample T test. The fatigue scale scores of the two groups of patients before treatment were compared (P>0.05), and the difference was not statistically significant, so they were comparable (see Table 6).
[0161] Table 6 Comparison of fatigue scale scores between the two groups of patients before treatment ( point)
[0162]
[0163] Treatment Outcomes
[0164] 1. Comparison of symptom scores of Yang deficiency constitution between the two groups of patients before and after treatment is shown in Table 7.
[0165] Table 7 Comparison of symptom scores of Yang deficiency constitution between the two groups of patients before and after treatment ( point)
[0166]
[0167] Note: △ means P<0.05 for intra-group comparison, # means P<0.05 for inter-group comparison.
[0168] (1) Intra-group comparison
[0169] According to statistical analysis, compared with before treatment, there were significant differences in the changes of various symptom scores between the Xuan paper moxibustion group and the moxibustion group after treatment (P<0.05);
[0170] (2) Comparison between groups
[0171] According to statistical analysis, the Chinese medicine Xuan paper Du-moxibustion group was superior to the Du-moxibustion group in terms of symptoms such as cold hands and feet, local fear of cold, wearing more clothes, avoiding raw and cold food, aversion to cold, and diarrhea, with significant differences (P < 0.05), while there was no statistically significant difference in symptoms of susceptibility to colds (P > 0.05).
[0172] 2. Comparison of Yang deficiency constitution transformation scores between the two groups of patients before and after treatment, see Table 8.
[0173] Table 8 Comparison of Yang deficiency constitution transformation scores between the two groups of patients before and after treatment ( point)
[0174]
[0175] Note: △ means P<0.05 for intra-group comparison, # means P<0.05 for inter-group comparison.
[0176] (1) Intra-group comparison
[0177] According to statistical analysis, there was a significant difference in the transformation score of yang deficiency constitution between the Chinese medicine Xuan paper Du-moxibustion group and the Du-moxibustion group before and after treatment (P<0.05).
[0178] (2) Comparison between groups
[0179] Statistical analysis showed that there was a significant difference in the improvement of the conversion score of Yang deficiency constitution between the two groups after treatment (P=0.001<0.05). The conversion score of the Chinese medicine Xuan paper Du-moxibustion group was reduced more than that of the Du-moxibustion group, indicating that the Chinese medicine Xuan paper Du-moxibustion group had an advantage over the control group in improving the overall Yang deficiency constitution.
[0180] 3. Comparison of fatigue scale scores between the two groups of patients before and after treatment is shown in Table 9.
[0181] Table 9 Comparison of fatigue scale scores between the two groups of patients before and after treatment ( point)
[0182]
[0183] Note: △ means P<0.05 for intra-group comparison, # means P<0.05 for inter-group comparison.
[0184] (1) Intra-group comparison
[0185] According to statistical analysis, the fatigue scores of the two groups after treatment were significantly different from those before treatment (P < 0.05), indicating that both the observation group and the control group can significantly improve the fatigue status of patients.
[0186] (2) Comparison between groups
[0187] Statistical analysis showed that there was a significant difference in improving fatigue status between the two groups after treatment (P=0.001<0.05), and the degree of reduction in the Chinese medicine Xuan paper Du-moxibustion group was greater than that in the Du-moxibustion group, indicating that the Chinese medicine Xuan paper Du-moxibustion group had an advantage over the control group in improving fatigue status overall.
[0188] 4. Comparison of the therapeutic effects of the two groups of patients with yang deficiency constitution after treatment is shown in Table 10.
[0189] Table 10 Comparison of the therapeutic effects of Yang deficiency constitution in two groups of patients after treatment (n, %)
[0190]
[0191] There were 30 cases in the Chinese medicine Xuan paper Du moxibustion group, of which 9 were markedly effective, 21 were effective, and 1 was ineffective, with a total effective rate of 96.7%; there were 30 cases in the Du moxibustion group, of which 5 were markedly effective, 22 were effective, and 3 were ineffective, with a total effective rate of 90%. The rank sum test showed that the difference between the two groups was statistically significant (P=0.036<0.05), indicating that the efficacy of Chinese medicine Xuan paper Du moxibustion in improving yang deficiency constitution was significantly better than that of the Du moxibustion group.
[0192] (III) Safety evaluation
[0193] During the trial, no serious adverse reactions or other serious clinical adverse reactions were found.
[0194] Typical cases:
[0195] Case 1: Wang, female, 43 years old, salesperson. She came to the clinic on March 8, 2022 with "recurrent polyarticular pain for 5 years, aggravated for 1 month." Bilateral shoulder abduction and dorsiflexion are limited, bilateral wrist joints are swollen, skin temperature is slightly higher, joint tenderness is obvious, bilateral proximal interphalangeal joints are flexed and deformed, joints are swollen and tender. Bilateral knee joints are swollen, tender, and joint flexion and dorsiflexion are limited. The right knee is prominent, symptoms are aggravated during activities, and there is occasional fever, with body temperature ranging from 37.2-37.8℃, accompanied by morning stiffness, which will last for about 1-2 hours and then relieve on its own, no headache, no nausea and vomiting, no chest pain and chest tightness, no abdominal pain, diarrhea, no gross hematuria, symptoms have recurred recently, gradually aggravated, and elbow flexion deformity has occurred, the tongue is pale and dark purple on both sides, the fur is thin and white, and the pulse is deep and slow. "Rheumatoid factor" quantitatively showed 107.5IU / ML↑, erythrocyte sedimentation rate 30mm / h; elbow and left ankle joint DR showed: osteoporosis of both elbow joints and left ankle joints, bone hyperplasia at the joint margin, narrow joint space, symptoms recurred recently, gradually worsened, and elbow flexion deformity occurred. The syndrome belongs to pain arthralgia, cold coagulation and blood stasis, Yingwei blockage, liver and kidney deficiency. Constitution identification suggests blood stasis and yang deficiency constitution, and the Chinese medicine Dujiu Xuan paper described in the present invention is given for Dujiu treatment once a week. After 3 months of follow-up, the patient's symptoms were significantly improved after treatment, and the symptoms such as joint pain, swelling, and stiffness were significantly alleviated, and the range of motion was significantly expanded. Follow-up and reexamination were carried out regularly.
[0196] Case 2: Zheng, male, 61 years old, retired. Due to "numbness of the right upper limb, progressively aggravated for half a year", pale complexion, listlessness, low voice, slow answering, muscle atrophy in both arms, skin and nails, pain sensation when pinched, inability to raise arms, weakness in grasping objects, and increasing difficulty in dressing and eating. The patient's thenar muscles of the hand atrophy significantly, and the right limbs have obvious temperature loss and pain disappearance. The biceps tendon reflex, triceps tendon reflex, abdominal wall reflex, cremaster reflex, perianal reflex and knee tendon reflex weakened, and Babinski sign was negative. Chinese medicine syndrome differentiation: congenital deficiency, insufficient essence, discouraged blood stasis, proposed to tonify the kidney and replenish essence, benefit the marrow and strengthen the brain, and tonify qi and activate the coordination. The Chinese medicine Dujiu Xuan paper described in the present invention was given for Dujiu treatment, once a week. After a follow-up visit 3 months later, the back and waist feeling basically returned to normal, the right arm was strong and the muscles were gradually plump. The two pulses of the moss returned to normal.
[0197] Case 3: Sun, female, 28 years old, civil servant. Two years ago, the patient had intermittent pain in the waist and buttocks on both sides without obvious cause, the left side was more severe, accompanied by stiffness in the lumbar sacral region, the pain was more severe at night and after rest, and relieved after activity. She was treated in a certain hospital and took "Yanxikang" and "Ibuprofen" intermittently for symptomatic treatment, and the symptoms were relieved. In the past six months, the low back pain has worsened, and the lumbar extension and scoliosis activities are limited. She took Yanxikang again, but the effect was not good, so she came to our hospital for treatment. The outpatient clinic was admitted with "ankylosing spondylitis". Since admission, the patient has been conscious, mentally OK, with good appetite and sleep, normal urination and defecation, pale tongue with dark purple on both sides, thin white fur, and slow pulse. The syndrome is pain and arthralgia, which is cold stagnation and blood stasis, Yingwei blockage, and liver and kidney deficiency. Scoliosis, extension, and rotation are limited. Chest expansion <2cm. There is tenderness at the sacroiliac joint and the local skin is not red. The 4-character test of the left lower limb is (+), and no obvious abnormalities are found in the other joints. Limb muscle strength and muscle tension are normal, physiological reflexes exist, and pathological signs are not elicited. ASO (-), RF: 80 units, ESR: 10mm / hour, lumbar anteroposterior and lateral plain film: lumbar vertebra 4-5 bone hyperplasia, 1st, 2nd, 4th intervertebral space narrowing. Pelvic plain film: left femoral head space narrowing, femoral head edge is unclear. Give the Chinese medicine moxibustion Xuan paper of the present invention for moxibustion treatment, 1 week 1 time. After 3 months, the patient's symptoms were significantly improved after treatment, and the symptoms such as joint pain, swelling, stiffness were significantly alleviated, and the range of motion was significantly expanded, and follow-up and reexamination were regularly carried out.
[0198] Case 4: Zhao, female, 60 years old, retired. Palpitations and anxiety for 1 month. The patient suddenly had palpitations and chest tightness and shortness of breath during sleep 1 month ago. The attack lasted for 2 hours and relieved on its own. After that, she dared not fall asleep. "Danshen dripping pills" were given, but the symptoms did not show obvious relief, sometimes light and sometimes heavy, and aggravated every time she was tired, rested poorly or mentally stressed. Current symptoms: chest tightness and shortness of breath, especially when moving, slightly pale complexion, cold body and cold limbs. She was thin, mentally average, with a pale tongue and thin white fur, and a deep and weak pulse. The electrocardiogram showed: heart rate 85 beats / min, sinus rhythm, normal electrocardiogram, and no obvious abnormalities. The patient was usually timid and fearful of cold and cold limbs. This attack occurred during sleep at night, due to the decline of yin and yang, the lack of heart yang, and the lack of nourishment of the mind. The Chinese medicine Xuan paper described in the present invention was given for moxibustion treatment once a week and a follow-up visit after 3 months. The patient felt that his palpitations were relieved, there was no chest tightness and shortness of breath, and the fear of cold and cold was improved, and the bowel movements were normal.
[0199] Case 5: Yu, male, 67 years old, retired. Due to "cold pain in the waist and back, soreness and fatigue for 1 year, aggravated for more than 2 months", the patient reported that he was easily fatigued during activities, pale complexion, listless, low voice, slow answering, hunchback and stooped, limited activities, fear of cold and love of warmth, aggravated by cold, especially in the lower limbs, frequent urination, or prolonged diarrhea, or edema, especially below the waist, which is concave when pressed. Pale tongue, white fur, deep and stringy pulse. The patient's temperature and pain sensation in the waist and back and right limbs are significantly reduced, Babinski sign (-). Chinese medicine diagnosis is atrophy (kidney yang deficiency), and it is planned to tonify the kidney and strengthen yang, replenish essence and benefit marrow for coordinated treatment. The Chinese medicine Xuan paper described in the present invention is given for Du moxibustion treatment, once a week. During the follow-up visit 3 months later, the patient reported that the symptoms of cold pain in the waist were alleviated, and the temperature and pain sensation in the waist, back and right limbs were basically back to normal. The muscle strength of the right arm was level 4, which was higher than before treatment. The muscles were gradually fuller, the range of motion of the right upper limb was improved, and the tongue coating and pulses returned to normal.
[0200] appendix:
[0201] Appendix A: TCM Constitution Questionnaire (TCM Association Standards)
[0202] Yang deficiency constitution
[0203]
[0204]
[0205] Note: Original score = sum of scores of each item. Conversion score = [(original score - 7) / (7 * 4)] * 100
[0206] Whether it is a yang deficiency constitution: if the conversion score is ≥40 points, yes; if the conversion score is 30-39 points, tend to be yes; if the conversion score is less than 30 points, no.
[0207] Appendix B Fatigue Scale (This scale is suitable for adults over 16 years old)
[0208] 1. Have you ever been troubled by fatigue?
[0209] 2. Do you need more rest? Yes No
[0210] 3. Do you feel sleepy or drowsy? Yes No
[0211] 4. Do you feel it is difficult to start doing things?
[0212] 5. Do you feel no difficulty in starting something, but feel overwhelmed as you continue?
[0213] 6. Do you feel that you are not strong enough?
[0214] 7. Do you feel that your muscle strength is less than before? Yes No
[0215] 8. Do you feel weak? Yes No
[0216] 9. Do you have difficulty concentrating? Yes No
[0217] *10. Is your mind as clear and agile as usual when thinking about problems?
[0218] 11. Do you have difficulty speaking clearly?
[0219] 12. When you speak, do you find it difficult to find the right words?
[0220] *13. Is your memory as good as before?
[0221] *14. Do you still like to do the things you used to do?
[0222] Result evaluation:
[0223] Please ask the patient to read each item carefully or the examiner to ask questions one by one, and circle "yes" or "no" according to the situation that best suits the patient. Except for the 3 items 10, 13, and 14, which are reverse-scored, that is, answering "yes" is scored as 0 points and answering "no" is scored as "1". The other 11 items are scored positively, that is, answering "yes" is scored as "1" and answering "no" is scored as "0". Add the scores of the 8 items from 1 to 8 to get the physical fatigue score, and add the scores of the 6 items from 9 to 14 to get the mental fatigue score. The total fatigue score is the sum of the physical and mental fatigue scores. The maximum physical fatigue score is 8, the maximum mental fatigue score is 6, and the maximum total score is 14. The higher the score, the more severe the fatigue.
[0224] References:
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[0233] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic features of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes that fall within the meaning and scope of the equivalent elements of the claims are included in the present invention.
[0234] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.
Claims
1. A Chinese medicinal rice paper with physiotherapy effect, characterized in that: The formula of the Chinese medicinal rice paper is: paper pulp, clean water, and Chinese medicinal liquid; The components of the Chinese medicine composition in the Chinese medicine liquid are: wormwood leaf, ginger, notopterygium root, angelica pubescens, Chuanwu, Kusnezoffii, Tianxianteng, Chuanxuduan, Sanguisorba officinalis, Diagnosiss of the Chinese medicine, Morus alba, Eucommia bark, Cat's claw, Fructus Lycopodii, and Licorice, and the ratio of the Chinese medicine components is 6:6:6:6:6:6:5:5:5:5:4:4:4:4:3; The ratio of the Chinese medicine composition to the water used for decocting the Chinese medicine composition is 1:6-7; The ratio of clean water to Chinese medicine solution is 1:1-1.2; The ratio of the mixture of clean water and Chinese medicine liquid to paper pulp is 1:20-25.
2. The Chinese medicinal rice paper with physiotherapy effect according to claim 1, characterized in that: After the Chinese medicinal rice paper is crushed, it is used as the content to wrap it to prepare moxibustion sticks.
3. The Chinese medicinal rice paper with physiotherapy effect according to claim 1, characterized in that: Traditional Chinese medicine rice paper is used as packaging paper for moxibustion sticks.
4. The Chinese medicinal rice paper with physiotherapy effect according to claim 1, characterized in that: The Chinese medicine rice paper is sealed in a package, and the Chinese medicine liquid obtained from the Chinese medicine composition is encapsulated in the package.
5. The Chinese medicinal rice paper with physiotherapy effect according to claim 1, characterized in that: Chinese medicinal rice paper is cut into rectangular pieces of paper, sealed and packaged, and used as hot compress pads.
6. The Chinese medicinal rice paper with physiotherapy effect according to claim 1, characterized in that: The Chinese medicinal rice paper with physiotherapy effect is crushed and mixed with Chinese medicinal liquid to prepare Dujiu moxibustion mud; the ratio of solid matter to Chinese medicinal liquid in the Dujiu moxibustion mud is 1:0.8-0.
9.
7. A method for preparing Chinese medicinal rice paper with physiotherapy effect, comprising the following steps: Step 1. Preparation of Chinese medicine solution 1. Use wormwood leaf, ginger, notopterygium root, angelica root, Chuanwu, Caowu, Tianxianteng, Chuanxuduan, Sanguisorba officinalis, Diagnosis, Morus alba, Morus alba, Eucommia barbata, Cat's claw, Scolopendra subspinipes, and licorice as Chinese medicine, boil in water, filter the residue, and make Chinese medicine liquid for use; The ratio of the drug components is 6:6:6:6:6:6:5:5:5:5:4:4:4:4:3; The ratio of the Chinese medicine composition to the water used for decocting the Chinese medicine composition is 1:6-7; Step 2. Paper preparation 1. Take mulberry bark as the main raw material, soak it in water, boil it with ash, steam it with alkali, and sieve it to get the skin pulp; The rice straw is threshed, soaked in ash, boiled, and sieved to obtain straw slurry; The skin pulp and straw pulp are mixed to obtain paper pulp; 2. Boil the water and let it cool, mix it with the Chinese medicine solution prepared in step 1 at a ratio of water: Chinese medicine solution = 1:1-1.2 and pour it into the paper trough; Pour the pulp gradually into the paper trough and use the paper curtain to scoop out the paper; The ratio of the mixture of water and Chinese medicine liquid to pulp is 1:20-25; drying; 3. Spray the drying paper to rehydrate it in the form of a spray, wherein the liquid used for the spray is the traditional Chinese medicine liquid prepared in step 1; 4. Dry and cut to obtain finished paper.
8. The method for preparing a Chinese medicinal rice paper with physiotherapy effect according to claim 7, characterized in that: The water boiling step adopts the above-mentioned proportion to boil over high heat, simmer for 15-18 minutes, and filter the medicinal liquid to obtain the first decoction liquid; continue to add water according to the above-mentioned proportion, boil over high heat for the second time, and simmer for 18-20 minutes to obtain the second decoction liquid; The first decoction liquid is mixed with the second decoction liquid to obtain the finished Chinese medicine liquid, which is then cooled for later use.
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