Tablet production apparatus and finished product detection method

By employing tablet production equipment and testing methods involving multiple pressing and adhesive spraying, the problem of interlayer adhesion in double-layer controlled-release tablets has been solved, improving product qualification rate and the accuracy of drug release.

CN117245970BActive Publication Date: 2026-01-02SHIJIAZHUANG KANGLI PHARM CO LTD
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Patent Information

Application Number
CN202311156900.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-09-08
Publication Date
2026-01-02
Estimated Expiration
2043-09-08

AI Technical Summary

Technical Problem

In the manufacturing process of dual-layer controlled-release tablets, the powder direct pressing technology has high requirements for material flowability, which makes it difficult to adhere the two drugs at the interface. In addition, materials with high flowability are prone to being mixed in, resulting in the release rate of the sustained-release layer not meeting the requirements.

Method used

Tablets are produced by multiple compressions and the application of adhesives. Defective products are removed by end-face and side inspections. Multiple extrusion strokes and an adhesive spraying device are used to ensure the quality of interlayer adhesion of the drug. Finished product inspection is performed using an image acquisition and analysis device.

Benefits of technology

This improved the product qualification rate of double-layer controlled-release tablets, solved the problem of poor adhesion between drug layers, and ensured that drug release met the expected time and concentration.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The application relates to a tablet production device and a finished product detection method. The production device comprises an upper punch module and a lower punch module, a middle die disc between the upper punch module and the lower punch module, a plurality of punch channels uniformly arranged on the middle die disc, a first feeder configured to place a first kind of powder into the punch channels, a second feeder configured to place a second kind of powder into the punch channels, a powder cleaning and humidifying module and a powder cleaning module both located on the side of the middle die disc, and a quality detection module located at the output end of the middle die disc, wherein the quality detection module is configured to detect the surface of the finished product. In a single rotation process, the upper punch module and the lower punch module have two extrusion strokes. The tablet production device and the finished product detection method disclosed by the application can improve the qualified rate of products by multiple compression and adhesive application, and can remove unqualified products through end face and side face detection.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of production equipment, in particular to a tablet production equipment and a finished product detection method. BACKGROUND

[0002] The double-layer controlled-release tablet is composed of two tablet layers with different release speeds, one layer is a quick-release layer, and the drug is released at a concentration of 90% within 30 minutes; the other layer is a slow-release layer, and the drug therein is slowly released, and the release time can be as long as 12-24 hours.

[0003] In the manufacturing process of the double-layer controlled-release tablet, two kinds of drugs need to be extruded, such as powder direct compression technology, but the powder direct compression technology has a relatively high requirement for the flowability of the material, and the bonding at the joint surface of the two drugs has certain difficulty. Moreover, the material with high flowability will also cause the problem of adulteration, which will cause the release speed of the drug in the slow-release layer to be less than the required release time. SUMMARY

[0004] The present application provides a tablet production equipment and a finished product detection method, which improves the qualified rate of the product by multiple compression and the application of adhesive, and rejects unqualified products by end face and side face detection.

[0005] The above-mentioned object of the present application is achieved by the following technical scheme:

[0006] In a first aspect, the present application provides a tablet production equipment, comprising:

[0007] an upper punch module and a lower punch module;

[0008] a middle die disc, which is located between the upper punch module and the lower punch module, and is uniformly provided with a plurality of punch channels on the middle die disc;

[0009] a first feeder configured to place a first powder into the punch channel;

[0010] a second feeder configured to place a second powder into the punch channel;

[0011] a powder cleaning and humidifying module and a powder cleaning module, both of which are located on the side of the middle die disc;

[0012] a quality detection module located at the output end of the middle die disc, and configured to detect the surface of the finished product;

[0013] In a first aspect, the present application provides a tablet production equipment, comprising:

[0014] The first feeder, the powder cleaning and humidifying module, the second feeder, the powder cleaning module and the quality detection module are sequentially arranged along the production direction;

[0015] The first feeder is located before the two extrusion strokes; the powder cleaning and humidifying module and the second feeder are located between the two extrusion strokes; the powder cleaning module and the quality detection module are located after the two extrusion strokes.

[0016] In a possible implementation manner of the first aspect, the powder cleaning and humidifying module comprises:

[0017] The first lifting platform;

[0018] The negative pressure bin is arranged on the first lifting platform;

[0019] The cleaning probe has a first end fixed in the negative pressure bin and a second end extending from the negative pressure bin;

[0020] The negative pressure channel is arranged in the cleaning probe and communicates with the side wall of the cleaning probe and the negative pressure bin at two ends respectively;

[0021] The hole-shaped adsorption layer is arranged on the side wall of the cleaning probe; and

[0022] The atomizing nozzle group is arranged on the second end of the cleaning probe.

[0023] In a possible implementation manner of the first aspect, the atomizing nozzle group comprises:

[0024] The atomizing nozzle is arranged in the recessed area on the second end of the cleaning probe; and

[0025] The connecting pipeline is located in the cleaning probe and connected with the atomizing nozzle.

[0026] In a possible implementation manner of the first aspect, the flow area of the recessed area tends to decrease in the direction close to the atomizing nozzle;

[0027] The maximum flow area of the recessed area is smaller than the diameter of the stamping channel.

[0028] In a possible implementation manner of the first aspect, the quality detection module comprises:

[0029] The first detection conveying belt;

[0030] The second detection conveying belt is arranged along the working direction of the first detection conveying belt, the working speed of the second detection conveying belt is not equal to the working speed of the first detection conveying belt, and the included angle between the first detection conveying belt and the second detection conveying belt is greater than or equal to 90°;

[0031] The face-changing fork is arranged on the second detection conveying belt, and the face-changing fork is configured to change the end face of the finished product from being in contact with the first detection conveying belt to being in contact with the second detection conveying belt; and

[0032] The two groups of image acquisition and analysis devices are located between the face-changing fork.

[0033] In a possible implementation of the first aspect, the second detection conveying belt is a plurality of second detection conveying belts.

[0034] The plurality of second detection conveying belts are arranged at intervals perpendicular to the working direction of the first detection conveying belt.

[0035] Further comprising:

[0036] A diverter connected to the output end of the center mold plate, the diverter configured to guide the finished product to the plurality of second detection conveying belts.

[0037] In a possible implementation of the first aspect, the diverter comprises:

[0038] An input channel connected to the output end of the center mold plate;

[0039] A plurality of output channels connected to the input channel and corresponding second detection conveying belts; and

[0040] A drain port and an electrically operated guide plate provided on the output channel, the electrically operated guide plate configured to block and open the drain port.

[0041] In a possible implementation of the first aspect, the image acquisition and analysis device comprises:

[0042] An image acquisition terminal configured to acquire surface images of the finished product; and

[0043] An image analyzer configured to analyze the images acquired by the first image acquisition terminal;

[0044] The image acquisition terminals in the first group are located on the side of the first detection conveying belt.

[0045] The image acquisition terminals in the second group are located on the side of the second detection conveying belt.

[0046] In a second aspect, the application provides a tablet finished product detection method, comprising:

[0047] Continuously acquiring a plurality of images of a finished product, one image comprising a partial end face and a partial side face of the finished product, the central angle corresponding to the partial end face being the same as the central angle corresponding to the partial side face;

[0048] Splicing a complete end face image and a complete side face image of a finished product using the plurality of images;

[0049] Performing grayscale processing on the complete end face image and the complete side face image;

[0050] Calculating the number of first pixel points in the complete end face image that exceed the allowed grayscale range and the number of second pixel points in the complete side face image that exceed the allowed grayscale range; and

[0051] When the sum of the number of the first pixel and the number of the second pixel exceeds the threshold, the finished product is marked as unqualified. Attached Figure Description

[0052] Figure 1 This is a schematic diagram showing the relative positions of an upper stamping module, a lower stamping module, and a middle die plate, as provided in this application.

[0053] Figure 2 This is a schematic diagram (top view) of a type of mold plate provided in this application.

[0054] Figure 3 This is a schematic diagram illustrating the working principle of an upper stamping module provided in this application.

[0055] Figure 4 This is a schematic diagram illustrating the working principle of a down-pressing module provided in this application.

[0056] Figure 5 This is a schematic diagram of the trajectory of a complete stroke of a stamping rod during two extrusion strokes, as provided in this application.

[0057] Figure 6 This is a schematic diagram of the production process of a tablet manufacturing equipment provided in this application.

[0058] Figure 7 This is a structural schematic diagram of a powder cleaning and humidification module provided in this application.

[0059] Figure 8 This is a schematic diagram of the internal structure of a cleaning probe provided in this application.

[0060] Figure 9 This is a partial structural diagram of a quality inspection module provided in this application.

[0061] Figure 10 This is a schematic diagram showing the relative positions of a first inspection conveyor belt and a second inspection conveyor belt, as provided in this application.

[0062] Figure 11 This is a schematic diagram of the structure of a reversible shift fork provided in this application.

[0063] Figure 12 This is a schematic diagram illustrating the working principle of a shunt provided in this application.

[0064] In the figure, 1, upper stamping die set, 2, lower stamping die set, 3, middle die plate, 4, first feeder, 5, second feeder, 6, powder cleaning and humidifying module, 7, powder cleaning module, 8, quality detection module, 31, stamping channel, 61, first lifting platform, 62, negative pressure bin, 63, cleaning probe, 64, negative pressure channel, 65, hole-shaped adsorption layer, 66, atomizing nozzle group, 81, first detection conveying belt, 82, second detection conveying belt, 83, surface changing fork, 84, image acquisition and analyzer, 85, flow divider, 661, atomizing nozzle, 662, connecting pipeline, 841, image acquisition terminal, 842, image analyzer, 851, input channel, 852, output channel, 853, leakage port, 854, electric guide plate. Embodiment

[0065] The technical solutions in the application are further described in detail below with reference to the drawings.

[0066] The application discloses a tablet production device, which is composed of an upper stamping die set 1, a lower stamping die set 2, a middle die plate 3, a first feeder 4, a second feeder 5, a powder cleaning and humidifying module 6, a powder cleaning module 7 and a quality detection module 8.

[0067] Please refer to Figure 1 The middle die plate 3 is located between the upper stamping die set 1 and the lower stamping die set 2, and a plurality of stamping channels 31 are uniformly arranged on the middle die plate 3. Figure 2 The upper stamping die set 1 and the lower stamping die set 2 can apply pressure to the powder in the stamping channels 31, so that the powder is bonded to make a double-layer controlled-release tablet.

[0068] Please refer to Figure 3 When the stamping rods in the upper stamping die set 1 pass through the rollers in sequence, the stamping rods will move downward under the pushing of the rollers, the stamping rods are connected by elastic ropes, and the stamping rods will reset under the pulling of the elastic ropes after being separated from the rollers.

[0069] Please refer to Figure 4 When the stamping rods in the lower stamping die set 2 pass through the rollers in sequence, the stamping rods will move upward under the pushing of the rollers, and the stamping rods reset by their own gravity.

[0070] The first feeder 4 is used to place the first kind of powder into the stamping channels 31, and the second feeder 5 is used to place the second kind of powder into the stamping channels 31, the first kind of powder and the second kind of powder correspond to the immediate-release layer and the sustained-release layer in the double-layer controlled-release tablet respectively.

[0071] In one rotation process (referring to the rotation of 360° of the upper stamping die set 1 and the lower stamping die set 2), the upper stamping die set 1 and the lower stamping die set 2 have two extrusion strokes, Figure 5As shown (rotating 360°), the two extrusion processes are used to extrude the first powder and the second powder respectively.

[0072] As shown in Figure 2 , the powder cleaning and humidifying module 6 and the powder cleaning module 7 are located at the side of the middle die plate 3, wherein the powder cleaning and humidifying module 6 is located between the first feeder 4 and the second feeder 5, and the function of the powder cleaning and humidifying module 6 is to clean the powder on the surface of the middle die plate 3 near the stamping channel 31 and the inner wall of the stamping channel 31, and to humidify the surface of the primary molding agent tablet in the stamping channel 31.

[0073] The powder cleaning module 7 is located behind the second feeder 5, and the function of the powder cleaning module 7 is to clean the stamping channel 31 after the tablet is discharged (the finished product is removed from the stamping channel 31). The structure of the powder cleaning module 7 is similar to that of the powder cleaning and humidifying module 6, and the difference is that the powder cleaning module 7 lacks the humidifying function.

[0074] The quality detection module 8 is located at the output end of the middle die plate 3, and the quality detection module 8 is configured to detect the surface of the finished product.

[0075] With the production direction (the rotating direction of the middle die plate 3) as the reference, the first feeder 4, the powder cleaning and humidifying module 6, the second feeder 5, the powder cleaning module 7, and the quality detection module 8 are sequentially arranged.

[0076] At the same time, the first feeder 4 is located before the two extrusion strokes;

[0077] The powder cleaning and humidifying module 6 and the second feeder 5 are located between the two extrusion strokes;

[0078] The powder cleaning module 7 and the quality detection module 8 are located after the two extrusion strokes.

[0079] Overall, the tablet production equipment provided by the present application uses a two-pressing method to produce a double-layer controlled-release tablet. After the first powder is placed in the stamping channel 31, it is first subjected to primary pressing to form a quick-release layer. However, it is specified that the pressure during primary pressing is less than that during secondary pressing, that is, after primary pressing, the density of the quick-release layer is less than that of the finished product.

[0080] Then, the powder cleaning and humidifying module 6 cleans the powder near the stamping channel 31 and the opening, and then sprays an adhesive, such as water or a solution (made of the first powder or the second powder), onto the surface of the quick-release layer.

[0081] Then, the second powder is placed in the stamping channel 31 and the pressing is continued to form a slow-release layer. The second pressing simultaneously applies pressure to the quick-release layer, so that the density of the quick-release layer reaches the required value, as shown in Figure 6 ​

[0082] Of course, the immediate release layer and the sustained release layer in the process can also be replaced.

[0083] The advantage of this way is that it fundamentally solves the problem of the unclear boundary between the immediate release layer and the sustained release layer, because if two kinds of powders are placed into the punching channel 31 and then pressed, it will cause the mixing of powders at the boundary between the immediate release layer and the sustained release layer, and the depth of the mixed area is also difficult to control, which will cause the patient to take the medicine, and the immediate release layer will cause a part of the sustained release layer to dissolve in advance when dissolving, and the patient's in vivo drug concentration in the entire drug cycle is not as expected.

[0084] In some examples, the first feeder 4 and the second feeder 5 both use a screw conveyor.

[0085] In some examples, please refer to Figure 7 and Figure 8 The powder cleaning and humidifying module 6 is composed of a first lifting platform 61, a negative pressure bin 62, a cleaning probe 63, a negative pressure channel 64, a hole-shaped adsorption layer 65 and an atomizing nozzle group 66, etc. The negative pressure bin 62 is installed on the first lifting platform 61 and can move in the vertical direction with the first lifting platform 61. The negative pressure bin 62 is in contact with the upper surface of the middle die disc 3 and adsorbs the powders falling on the upper surface of the middle die disc 3.

[0086] The first end of the cleaning probe 63 is fixed in the negative pressure bin 62, and the second end extends out of the negative pressure bin 62, which is used to extend into the punching channel 31 below the negative pressure bin 62 and adsorb the powders on the inner wall of the punching channel 31. The negative pressure channel 64 is arranged in the cleaning probe 63, and the two ends of the negative pressure channel 64 are respectively communicated with the side wall of the cleaning probe 63 and the negative pressure bin 62, so as to realize the adsorption of the powders on the inner wall of the punching channel 31 by means of the negative pressure in the negative pressure bin 62.

[0087] Meanwhile, the hole-shaped adsorption layer 65 is added to the side wall of the cleaning probe 63, which can reduce the airflow velocity at the side wall of the cleaning probe 63 and improve the uniformity of adsorption.

[0088] The cleaning probe 63 also undertakes the task of spraying adhesive to the surface of the immediate release layer after the first pressing. The specific implementation of this task is realized by the atomizing nozzle group 66 on the second end of the cleaning probe 63. After the cleaning probe 63 enters the punching channel 31 and stops moving, the atomizing nozzle group 66 sprays adhesive to the surface of the immediate release layer after the first pressing.

[0089] In some possible implementations, the atomizing nozzle group 66 is composed of an atomizing nozzle 661 and a connecting pipe 662, the atomizing nozzle 661 is located in a recessed area on the second end of the cleaning probe 63, and the connecting pipe 662 is located in the cleaning probe 63 and connected with the atomizing nozzle 661, and the connecting pipe 662 is also connected with an external liquid supply pump.

[0090] Further, the flow area of the recessed area tends to decrease in the direction of the atomizing nozzle 661;

[0091] Further, the maximum flow area of the recessed area is smaller than the diameter of the punching channel 31.

[0092] The purpose of limiting the recessed area is to avoid the adhesive from contacting the inner wall of the punching channel 31.

[0093] In some examples, referring to Figures 9 to 11 , the quality detection module 8 is composed of a first detection conveying belt 81, a second detection conveying belt 82, a surface changing fork 83, an image acquisition and analyzer 84, and the like, the first detection conveying belt 81 is connected with the output end of the middle mold disc 3, and the finished product removed from the middle mold disc 3 first falls on the first detection conveying belt 81 and the second detection conveying belt 82.

[0094] It should be noted that the output end of the middle mold disc 3 is provided with a channel, and the finished product will slide on the channel in sequence.

[0095] The second detection conveying belt 82 is arranged along the working direction of the first detection conveying belt 81, and the included angle between the first detection conveying belt 81 and the second detection conveying belt 82 is greater than or equal to 90°. In this way, the first detection conveying belt 81 and the second detection conveying belt 82 can simultaneously drive the finished product to roll forward, and in order to ensure that the finished product can continuously roll, the working speed of the second detection conveying belt 82 is required to be different from (greater than or less than) the working speed of the first detection conveying belt 81.

[0096] The continuous rolling of the finished product is realized by the speed difference between the first detection conveying belt 81 and the second detection conveying belt 82.

[0097] The surface changing fork 83 is arranged on the second detection conveying belt 82, and the function is to change the end surface of the finished product from being in contact with the first detection conveying belt 81 to being in contact with the second detection conveying belt 82, so that the other end surface of the finished product can be shot by the image acquisition and analyzer 84 and analyzed.

[0098] As shown in Figure 11 , the working surface of the surface changing fork 83 is an inclined surface, after the finished product contacts the inclined surface, the finished product is separated from the first detection conveying belt 81, then rotates under the guidance of the inclined surface, and finally falls on the second detection conveying belt 82.

[0099] In some possible implementations, the first detection conveying belt 81 is made of a material with a relatively small friction coefficient, and the second detection conveying belt 82 is made of a material with a relatively large friction coefficient.

[0100] Here, the shooting process of the finished product can also be divided into two stages (with the face changing fork 83 as the dividing point), in the first stage, the first end face and the side face of the finished product are mainly shot, and in the second stage, the second end face of the finished product is mainly shot.

[0101] The number of image acquisition and analyzers 84 is two groups, the first group of image acquisition and analyzers 84 is located in front of the face changing fork 83, and the second group of image acquisition and analyzers 84 is located behind the face changing fork 83.

[0102] In some examples, the number of second detection conveying belts 82 is multiple, and these second detection conveying belts 82 are arranged at intervals perpendicular to the working direction of the first detection conveying belt 81, so as to improve the detection speed of the finished product, which solves the problem of mismatch between production speed and detection.

[0103] The switching of the second detection conveying belt 82 is realized through the diverter 85, which is connected with the output end of the middle mold disc 3 and connected with each second detection conveying belt 82, and is configured to guide the finished product to the multiple second detection conveying belts 82.

[0104] Please refer to Figure 9 and Figure 12 , the diverter 85 is composed of an input channel 851, an output channel 852, a leakage port 853 and an electric guide plate 854, the input channel 851 is connected with the output end of the middle mold disc 3, and the multiple output channels 852 are all connected with the input channel 851 and respectively connected with the corresponding second detection conveying belts 82.

[0105] Each output channel 852 is provided with a leakage port 853, and the leakage port 853 is used to make the finished product on the output channel 852 fall on the next output channel 852. An electric guide plate 854 is also installed on the output channel 852, and the electric guide plate 854 is used to block and open the leakage port 853.

[0106] When the leakage port 853 is blocked, the finished product moves on the output channel 852; when the leakage port 853 is opened, the finished product moves along the electric guide plate 854 to the next output channel 852.

[0107] In some examples, the image acquisition and analyzer 84 is composed of an image acquisition terminal 841 and an image analyzer 842, the image acquisition terminal 841 is configured to acquire the surface image of the finished product, and the image analyzer 842 is configured to analyze the image acquired by the first image acquisition terminal 841.

[0108] The number of image acquisition and analyzers 84 is two groups, wherein the image acquisition terminal 841 in the first group is located on the side of the first detection conveying belt 81, and the image acquisition terminal 841 in the second group is located on the side of the second detection conveying belt 82.

[0109] The application also discloses a tablet finished product detection method, comprising the following steps:

[0110] S101, continuously acquiring multiple images of a finished product, one image comprising a partial end face and a partial side face of the finished product, the central angle corresponding to the partial end face being the same as the central angle corresponding to the partial side face;

[0111] S102, splicing one complete end face image and one complete side face image of the finished product using the multiple images;

[0112] S103, performing gray scale processing on the complete end face image and the complete side face image;

[0113] S104, calculating the number of first pixel points in the complete end face image exceeding the allowed gray scale range and the number of second pixel points in the complete side face image exceeding the allowed gray scale range; and

[0114] S105, when the sum of the number of first pixel points and the number of second pixel points is greater than a threshold value, marking the finished product as unqualified.

[0115] The contents in steps S101 to S105 are that the image acquisition terminal 841 is used to acquire images of the finished product in a rotating state, one part of each image is taken, and then multiple parts are used to splice a complete image of the finished product.

[0116] The reason for taking one part of each image is that there is an included angle between the image acquisition terminal 841 and the finished product, which leads to incomplete display of the finished product in the image, so multiple images are used for splicing.

[0117] After splicing, a complete end face image and a complete side face image of the finished product can be obtained, and then gray scale processing is performed on the complete end face image and the complete side face image. The colors of the immediate-release layer and the sustained-release layer are different, and different gray scale values are expressed after gray scale processing. At this time, the sustained-release layer component (surface) doped in the immediate-release layer region and the immediate-release layer component (surface) doped in the sustained-release layer region can be analyzed.

[0118] And because the tablet production equipment provided by the application is used for production, the mixing phenomenon of the immediate-release layer component and the sustained-release layer component in the middle region of the finished product basically does not occur.

[0119] The embodiments of the present application are all the preferred embodiments of the present application, and do not limit the protection scope of the present application, so that: any equivalent changes made according to the structure, shape, principle of the present application should be covered within the protection scope of the present application.

Claims

1. A tablet production apparatus, characterized by comprising: The device comprises: an upper stamping die set (1) and a lower stamping die set (2); a middle die plate (3) located between the upper stamping die set (1) and the lower stamping die set (2), the middle die plate (3) being provided with a plurality of stamping channels (31) uniformly distributed thereon; a first feeder (4) configured to place a first kind of powder into the stamping channels (31); a second feeder (5) configured to place a second kind of powder into the stamping channels (31); a powder cleaning and humidifying module (6) and a powder cleaning module (7) located on one side of the middle die plate (3); a quality detection module (8) located at an output end of the middle die plate (3), the quality detection module (8) being configured to detect the surface of a finished product; wherein, in one rotation process, the upper stamping die set (1) and the lower stamping die set (2) have two extrusion strokes; the first feeder (4), the powder cleaning and humidifying module (6), the second feeder (5), the powder cleaning module (7) and the quality detection module (8) are sequentially arranged along the production direction; the first feeder (4) is located before the two extrusion strokes; the powder cleaning and humidifying module (6) and the second feeder (5) are located between the two extrusion strokes; the powder cleaning module (7) and the quality detection module (8) are located after the two extrusion strokes; the powder cleaning and humidifying module (6) comprises: a first lifting platform (61); a negative pressure bin (62) provided on the first lifting platform (61); a cleaning probe (63) having a first end fixed in the negative pressure bin (62) and a second end extending out of the negative pressure bin (62); a negative pressure channel (64) provided in the cleaning probe (63) and communicating with the sidewall of the cleaning probe (63) and the negative pressure bin (62) at two ends thereof; a hole-shaped adsorption layer (65) provided on the sidewall of the cleaning probe (63); and a group of atomizing nozzles (66) provided on the second end of the cleaning probe (63).

2. The tablet producing apparatus according to claim 1, wherein The group of atomizing nozzles (66) comprises: an atomizing nozzle (661) provided in a recessed area on the second end of the cleaning probe (63); and a connecting pipeline (662) located in the cleaning probe (63) and connected with the atomizing nozzle (661).

3. The tablet producing apparatus according to claim 2, wherein In the direction close to the atomizing nozzle (661), the flow area of the recessed area tends to decrease; the maximum flow area of the recessed area is smaller than the diameter of the stamping channel (31).

4. The tablet producing apparatus according to any one of claims 1 to 3, characterized by The quality detection module (8) comprises: a first detection conveying belt (81); a second detection conveying belt (82) having a working speed different from that of the first detection conveying belt (81), and the included angle between the first detection conveying belt (81) and the second detection conveying belt (82) is greater than or equal to 90°; a surface changing fork (83) provided on the second detection conveying belt (82), the surface changing fork (83) being configured to change the end surface of the finished product from being in contact with the first detection conveying belt (81) to being in contact with the second detection conveying belt (82); and two groups of image acquisition and analysis devices (84), the surface changing fork (83) being located between the two groups of image acquisition and analysis devices (84).

5. The tablet producing apparatus according to claim 4, wherein The number of the second detection conveying belts (82) is multiple. A plurality of second detection conveyors (82) are arranged along the working direction of the first detection conveyor (81) at intervals, and the second detection conveyors (82) are perpendicular to the working direction of the first detection conveyor (81); Further comprising: A diverter (85) connected to the output end of the middle mold disc (3), and the diverter (85) is configured to guide the finished product to the plurality of second detection conveyors (82).

6. The tablet producing apparatus according to claim 5, wherein The diverter (85) comprises: An input channel (851) connected to the output end of the middle mold disc (3); A plurality of output channels (852) connected to the input channel (851) and corresponding second detection conveyors (82); and A drain port (853) and an electric guide plate (854) arranged on the output channel (852), and the electric guide plate (854) is configured to block and open the drain port (853).

7. The tablet producing apparatus according to claim 5, wherein The image acquisition and analyzer (84) comprises: An image acquisition terminal (841) configured to acquire a surface image of the finished product; and An image analyzer (842) configured to analyze the image acquired by the image acquisition terminal (841); Wherein, the image acquisition terminal (841) in the first group is located on the side of the first detection conveyor (81); The image acquisition terminal (841) in the second group is located on the side of the second detection conveyor (82).

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