Sampling control method, device, equipment and sample analyzer, medium

Abstract

The present application provides a sampling control method, device, equipment, sample analyzer, and medium. The sampling control method includes: in the process of controlling a sampling needle to perform a current sampling task, after controlling the sampling needle to perform a sample aspiration action, determining whether the current sample aspiration amount of the sampling needle is a normal sample aspiration amount based on the post-sampling characteristic value of the sampling needle's characteristic parameter; when it is determined that the sample aspiration amount of the sampling needle is a normal sample aspiration amount, controlling the sampling needle to move out of the sample container and move the sampling needle to a sample dripping position to drip the sample, thereby completing the current sampling task; otherwise, controlling the sampling needle to perform a sample spitting action, and after the sampling needle completes the sample spitting action, controlling the sampling needle to return to perform the sample aspiration action, i.e., re-executing the sample aspiration action in the current sampling task. Therefore, the sampling control method can improve the accuracy of sample aspiration and reduce equipment maintenance time.

Description

Technical Field

[0001] The present application relates to the field of medical device technology, and in particular to a sampling control method, device, equipment, sample analyzer, and medium. Background Art

[0002] In in vitro diagnostic instruments, the accuracy of the sample volume plays a crucial role in instrument performance, directly impacting whether the instrument can meet performance requirements. Numerous factors can influence sampling accuracy, such as the presence of empty suction, bubbles, floccules, or clots in the sample needle during the aspiration process, all of which can lead to system aspiration anomalies.

[0003] In the existing sampling control process, every time the detection equipment detects a sampling abnormality in the sampling needle, it will stop sampling and issue a fault prompt. Sampling can only be resumed after the staff has performed fault detection, resulting in low sampling efficiency. Summary of the Invention

[0004] In order to solve the existing technical problems, the present application provides a sampling control method, device, equipment, sample analyzer and medium with high sampling accuracy and reduced maintenance time of sampling equipment.

[0005] A sampling control method, comprising:

[0006] In the process of controlling the sampling needle to perform the current sampling task, after the sampling needle completes the sample aspiration action, obtaining a post-sampling characteristic value of a characteristic parameter of the sampling needle, wherein the characteristic parameter is a parameter associated with the sample aspiration amount of the sampling needle;

[0007] Determining whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount according to the characteristic value after the sample aspirated;

[0008] If so, the sampling needle is controlled to be removed from the sample container, and the sampling needle is moved to the sample dripping position to drip the sample, thereby completing the current sampling task;

[0009] If not, the sampling needle is controlled to perform the sample-discharging action, and after the sampling needle completes the sample-discharging action, the sampling needle is controlled to return to perform the sample-sucking action.

[0010] A sampling control device, comprising:

[0011] A determination module, configured to determine whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount after the sampling needle completes the current sample aspirating action;

[0012] a first control module configured to control the sampling needle to be removed from the sample container and to move the sampling needle to a sample dropping position for sample dropping when determining whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount;

[0013] The second control module is used to control the sampling needle to perform a sample discharge action when determining whether the sample aspirated amount of the sampling needle is a normal sample aspirated amount, and control the sampling needle to return to perform the sample aspirating action after the sampling needle completes the sample discharge action.

[0014] A sampling device includes a processor and a memory, wherein the memory stores a computer program executable by the processor, and when the computer program is executed by the processor, the sampling control method as described above is implemented.

[0015] A sampling device, comprising a sampling controller, a sampling needle and a sample aspiration detection component for implementing the sampling control method;

[0016] The sample aspiration detection component is connected to the sampling controller and the sampling needle respectively, and is used to detect the characteristic parameters of the sampling needle after the sampling needle completes the current sample aspiration action, obtain the characteristic value after sample aspiration, and send the characteristic value after sample aspiration to the sampling controller.

[0017] A sample analyzer comprises a detection and analysis device and the sampling equipment as described above, wherein the detection and analysis device performs detection and analysis on a sample to be tested collected by the sampling equipment to obtain detection and analysis data of the sample to be tested.

[0018] A computer-readable storage medium stores a computer program, and when the computer program is executed by a control device, the sampling control method as described above is implemented.

[0019] As can be seen from the above, the sampling control method provided by the present application determines whether the current sample aspiration volume of the sampling needle is a normal sample aspiration volume based on the post-sampling characteristic value of the characteristic parameter of the sampling needle after the sampling needle completes the sample aspiration action during the process of controlling the sampling needle to perform the current sampling task. When it is determined that the sample aspiration volume of the sampling needle is a normal sample aspiration volume, the sampling needle is controlled to be removed from the sample container and moved to the sample dripping position to drip the sample, thereby completing the current sampling task. Otherwise, the sampling needle is controlled to perform the sample spitting action, and after the sampling needle completes the sample spitting action, the sampling needle is controlled to return to perform the sample aspiration action, that is, to re-execute the sample aspiration action in the current sampling task. Therefore, the sampling control method can improve the accuracy of sample aspiration and reduce equipment maintenance time. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 A flow chart of a sampling control method according to an embodiment of the present application;

[0021] Figure 2A flow chart of a sample control method according to another embodiment of the present application;

[0022] Figure 3 Schematic diagram of the sampling needle aspiration process in the sampling control method provided in an embodiment of the present application;

[0023] Figure 4 Schematic diagram of a flow chart of a sampling control method provided according to some embodiments of the present application;

[0024] Figure 5 A schematic diagram of the structure of a sampling control device provided according to some embodiments of the present application;

[0025] Figure 6 A schematic diagram of the structure of a sampling device provided according to an embodiment of the present application;

[0026] Figure 7 A schematic diagram of the structure of a sampling device provided according to other embodiments of the present application;

[0027] Figure 8 The present invention is a flowchart of a method for performing a sampling task by a sampling device provided in an embodiment of the present application. DETAILED DESCRIPTION

[0028] The technical solution of this application is further elaborated in detail below with reference to the accompanying drawings and specific embodiments.

[0029] In order to make the purpose, technical solutions and advantages of this application clearer, the application will be further described in detail below with reference to the accompanying drawings. The described embodiments should not be regarded as limiting this application. All other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of this application.

[0030] In the following description, the expression "some embodiments" is involved, which describes a subset of all possible embodiments. It should be noted that "some embodiments" may be the same subset or different subsets of all possible embodiments, and may be combined with each other without conflict.

[0031] In the following description, the terms "first, second, and third" are merely used to distinguish similar objects and do not represent a specific ordering of the objects. It is understandable that "first, second, and third" can be interchanged with a specific order or sequence where permitted, so that the embodiments of the present application described herein can be implemented in an order other than that illustrated or described herein.

[0032] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this application pertains. The terms used herein are for the purpose of describing the embodiments of this application only and are not intended to limit this application.

[0033] See also Figure 1 As shown, it is a flow chart of the sampling control method provided in accordance with an embodiment of the present application. The sampling control method provided in accordance with an embodiment of the present application can be applied to a sample analyzer. The sample analyzer samples and detects the sample to be tested using the sampling control method to obtain a sample test result corresponding to the sample to be tested. The sample analyzer can be a hematology analyzer, an immunoassay analyzer, or a biochemical analyzer, etc. In some embodiments, the sampling control method can also be applied to a sampling device, which samples the sample to be tested according to the sampling control method for detection by the sample analyzer. The sample analyzer and the sampling device to which the sampling control method provided in accordance with an embodiment of the present application is applied will be described in detail later. The sampling control method provided in this embodiment includes steps S02, S04, S06, and S08, which are described in detail as follows.

[0034] S02: in the process of controlling the sampling needle to perform the current sampling task, after the sampling needle completes the sample aspiration action, obtaining the post-sampling characteristic value of the characteristic parameter of the sampling needle, wherein the characteristic parameter is a parameter associated with the sample aspiration amount of the sampling needle.

[0035] When the sample analyzer is testing and analyzing the sample to be tested, it is necessary to use a sampling operation to perform a sampling operation on the sample to be tested. The sample to be tested includes but is not limited to blood, urine, sweat, or tissue fluid of the subject to be tested. When the sample analyzer is testing the sample to be tested, it may be necessary to control the sampling to perform multiple sampling tasks. Controlling the sampling needle for each sampling task includes: controlling the sampling needle to move from an initial position to a first direction so that the needle tip of the sampling needle pierces the container cap of the sample container, and then continues to move to a sample aspiration position below the liquid level of the sample to be tested, and performs a sample aspiration at the sample aspiration position. After the sample aspiration action is completed, the sampling needle is controlled to move in a second direction opposite to the first direction to remove the sampling needle from the sample container and then move to a sample dripping position for sample dripping. After the sample dripping is completed, the sampling needle is controlled to return to the initial position. If the sampling needle needs to perform the next sampling task after completing the current task, the sampling needle is controlled to continue to perform the next sampling task according to the above process.

[0036] One end of the sampling needle is a needle tip, and the other end is connected to a power source via a sampling line. The sampling line is used to transmit power output by the power source to the sampling needle. The power source includes a pneumatic pump or syringe that outputs positive and negative air pressure into the sampling needle, and also includes a motor for driving the sampling needle. By controlling the motor, the sampling needle can be moved according to a set timing.

[0037] The characteristic parameter of the sampling needle is related to the sample aspirating volume of the sampling needle, that is, the characteristic parameter refers to the characteristic parameter that can characterize the current sample aspirating volume in the sampling needle, and the characteristic value of the characteristic parameter changes with the current sample aspirating volume of the sampling needle. The characteristic parameter is such as the pressure in the sampling needle, or the page height of the sample to be tested in the sampling needle, or the number of particles of the sample to be tested in the sampling needle, etc. The characteristic value after sample aspiration refers to the value of the characteristic parameter of the sampling needle after the sampling needle performs the sample aspirating action, that is, after the sampling needle performs the sample aspirating action, when there is a sample to be tested sucked into the sampling needle, the value of the characteristic parameter of the sampling needle.

[0038] S04: Determine whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount according to the characteristic value after the sample aspirated.

[0039] Since the characteristic parameter of the sampling needle is related to the sample aspirating volume of the sampling needle, by obtaining the characteristic value after sample aspirating, the current sample aspirating volume information of the sampling needle can be obtained according to the characteristic value after sample aspirating, and then it is determined whether the sample aspirating volume of the sampling needle meets the set sample aspirating volume. If it meets the set sample aspirating volume, it means that the sample aspirating volume of the sampling needle is the normal sample aspirating volume, and then it means that the current sample aspirating action is a normal sample aspirating action. Therefore, the current sampling task can be continued to be executed according to the normal process, that is, when it is determined that the sample aspirating volume is normal, execute S06, otherwise it means that the current sample aspirating volume is an abnormal sample aspirating volume, and then execute S08.

[0040] S06: When the sample aspirating amount of the sampling needle is a normal sample aspirating amount, the sampling needle is controlled to be removed from the sample container, and the sampling needle is moved to a sample dripping position to drip the sample, thereby completing the current sampling task.

[0041] When the current sample aspiration volume of the sampling needle is the normal sample aspiration volume, the sample aspiration action currently performed by the sampling needle is considered to be a valid sample aspiration action, and the sample to be tested in the normal sample aspiration volume in the sampling needle can be transported to the sample dropping position for sample dropping. Specifically, the sampling needle is first controlled to move along the second direction mentioned above so that the sampling needle is pulled out of the sample container, and then the sampling needle is controlled to move to the sample dropping position according to a preset movement trajectory for sample dropping. In some embodiments, the sample dropping position can also be the detection position of a sample analyzer. After the sampling needle drops the sample to be tested sucked into the detection position, the detection component in the sample analyzer detects and analyzes the sample to be tested at the detection position to obtain corresponding detection and analysis results.

[0042] S08: When the sample aspirated amount of the sampling needle is an abnormal sample aspirated amount, the sampling needle is controlled to perform a sample spitting action, and after the sampling needle completes the sample spitting action, the sampling needle is controlled to return to perform the sample aspirating action.

[0043] When the current sample aspiration volume of the sampling needle is an abnormal sample aspiration volume, if the sample to be tested with the abnormal sample aspiration volume continues to be moved to the sample dripping position for dripping, the sample volume to be tested by the sample analyzer does not meet the detection requirements, which may cause inaccurate sample analysis results. According to the practice of the prior art, when it is found that the sample aspiration volume of the sampling needle is an abnormal sample aspiration volume, the current sampling task will be terminated and the fault information will be reported to the maintenance personnel to perform corresponding troubleshooting. After the fault is eliminated, the sampling needle will be controlled to re-execute the current sampling task. However, in the sampling control method provided in the embodiment of the present application, when the sample aspiration volume of the sampling needle is abnormal, the sample aspiration action currently performed by the sampling needle is considered to be an invalid sample aspiration action, and the sampling needle is first controlled to perform the sample spitting action, and after the sample spitting action is completed, it returns to the sample aspiration action of the current sampling task. By performing the sample spitting action after the sample suction is abnormal, the abnormal sample to be tested that is sucked into the sampling needle can be excluded from the sample container, and the sample suction action is performed again. Only when the sample suction amount is the normal sample suction amount will it be moved to the sample dropping position for sample dropping. Since abnormal sample suction is sometimes not caused by a malfunction of the sampling equipment, in the prior art, a fault alarm is issued each time an abnormal sample suction is detected, which increases the maintenance frequency and time of the equipment, resulting in an increase in labor costs, and is also not conducive to improving the detection efficiency of the sample analyzer. The sample control method provided in the embodiment of the present application, when determining abnormal sample suction, first controls the sampling needle to perform the sample spitting action to discharge the sucked-in foreign matter, and then returns to perform the sample suction action and re-sucks the sample. After the sample suction action is performed again, the sample suction amount of the sampling needle may be the normal sample suction amount, thereby effectively reducing the maintenance frequency and reducing the time cost of the maintenance personnel, while also helping to improve the accuracy of sample suction.

[0044] As can be seen from the above, the sampling control method provided by the embodiment of the present application, in the process of controlling the sampling needle to perform the current sampling task, after the sampling needle completes the sample aspiration action, determines whether the current sample aspiration amount of the sampling needle is a normal sample aspiration amount based on the post-sample aspiration characteristic value of the characteristic parameter of the sampling needle. When it is determined that the sample aspiration amount of the sampling needle is a normal sample aspiration amount, the sampling needle is controlled to be removed from the sample container and moved to the sample dripping position to drip the sample, completing the current sampling task. Otherwise, the sampling needle is controlled to perform the sample spitting action, and after the sampling needle completes the sample spitting action, the sampling needle is controlled to return to perform the sample aspiration action, that is, re-execute the sample aspiration action in the current sampling task. Therefore, the sampling control method can improve the accuracy of sample aspiration and reduce equipment maintenance time.

[0045] See also Figure 2 , which is a flow chart of a sample control method according to another embodiment of the present application. In this embodiment, S04 may specifically include S041. S02, S06, and S08 are the same as described above and will not be repeated here. S041 is described in detail as follows.

[0046] S041: Determine whether the sample aspirated amount of the sampling needle is an abnormal sample aspirated amount based on the difference between the characteristic value after sample aspirating and the characteristic value before sample aspirating, wherein the characteristic value before sample aspirating is the value corresponding to the characteristic parameter before the sampling needle performs the current sample aspirating action.

[0047] The characteristic value before sampling is the value corresponding to the characteristic parameter of the sampling needle before the sampling needle performs the sampling action. The difference between the characteristic value after sampling and the characteristic value before sampling refers to the change in the characteristic value of the characteristic parameter of the sampling needle before and after sampling. For example, the difference between the characteristic value after sampling and the characteristic value after sampling can be calculated to obtain the corresponding difference result, and then the sample aspirated volume in the sampling needle is determined based on the difference result, and then the sample aspirated volume in the sampling needle is compared with the reference sample aspirated volume corresponding to the current sampling task. If the error between the sample aspirated volume in the sampling needle and the reference sample aspirated volume is within the allowable error range, it means that the current sample aspirated volume of the sampling needle is a normal sample aspirated volume, otherwise it means that the sample aspirated volume of the sampling needle is an abnormal sample aspirated volume.

[0048] Furthermore, in some embodiments, before executing S041, the sampling control method further includes: obtaining the characteristic parameter in the sampling needle before controlling the sampling needle to perform a sample aspiration action, and obtaining a pre-sample aspiration characteristic value corresponding to the characteristic parameter. The pre-sample aspiration characteristic value is a value preset by a sampling device implementing the sampling control method, or may be a value obtained by a sampling volume detection component detecting the characteristic parameter before the sampling needle performs a sample aspiration action.

[0049] In some embodiments, the characteristic parameter described in the sampling control method is the pressure inside the sampling needle, and the characteristic value after sampling is performed is the pressure value when the sampling needle has the current amount of sample to be tested after the sampling needle performs the sampling action. The characteristic value before sampling is the pressure value when the sampling needle has no sample to be tested before the sampling needle performs the sampling action. Specifically, after the sampling needle completes the sampling action, the pressure inside the sampling needle is detected by controlling the pressure detection component to obtain the corresponding pressure value, that is, the characteristic value after sampling is obtained. The pressure detection component is such as a pressure sensor. The pressure detection component can directly detect the pressure value inside the sampling needle, or it can detect the pressure value inside the sampling pipeline connected to the sampling needle as the pressure value inside the sampling needle. Because the sampling needle is connected to the sampling pipeline, the pressure value inside the sampling needle and the pressure value inside the sampling pipeline can be considered to be equal or relatively close.

[0050] In some embodiments, the characteristic parameter described in the sampling control method is the liquid level height of the sample to be tested in the sampling needle, and the characteristic value after sampling is the liquid level height of the sample to be tested in the sampling needle after the sampling needle performs the sampling action. The characteristic value before sampling is the liquid level height of the sample to be tested in the sampling needle before the sampling needle performs the sampling action. Since there is no sample to be tested in the sampling needle before the sampling needle performs the sampling action, it can be considered that the liquid level height of the sample to be tested in the sampling needle before the sampling needle performs the sampling action is zero. After the sampling needle completes the sampling action, the liquid level detection component can be controlled to obtain the liquid level height of the sample to be tested in the sampling needle. The liquid level detection component can be an optical coupler arranged above the sampling needle, and the height of the sample to be tested in the sampling needle is obtained by obtaining the sensing information of the optical coupler.

[0051] Furthermore, in some embodiments, in S08: controlling the sampling needle to perform the sample spitting action is specifically as follows: controlling the power source connected to the sampling needle to output positive air pressure to the sampling needle, so that the pressure inside the sampling needle is in a positive air pressure state, so as to spit out the sample to be tested sucked into the sample container by the sampling needle.

[0052] Positive pressure refers to pressure above the first atmospheric pressure, while subsequent negative pressure refers to pressure below one atmospheric pressure. The pressure of the sample to be tested in the sample container can be considered to be one atmospheric pressure. When the sampling needle is in a negative pressure state (i.e., the pressure inside the sampling needle is negative and lower than the pressure of the sample to be tested in the sample container), the sample to be tested is drawn into the sampling needle due to the pressure difference, completing the sample aspiration process. The sampling needle's sample aspiration process refers to the action of the sampling needle aspirating the sample to be tested at the sample aspiration position. When the sampling needle is in a positive pressure state (i.e., the pressure inside the sampling needle is positive and higher than the pressure of the sample to be tested in the sample container), the sample to be tested in the sampling needle is expelled from the sampling needle due to the pressure difference, i.e., the sampling needle is discharged back into the sample container, completing the sample discharge process. The sampling needle's sample discharge process refers to the action of the sampling needle discharging the sample to be tested into the sample container at the current sample aspiration position.

[0053] In some embodiments, the sampling control method further includes: in the process of controlling the sampling needle to move toward the current suction position, before the needle tip of the sampling needle moves into the sample to be tested in the sample container, controlling the pressure in the sampling needle to be in a negative pressure state. Figure 3 As shown in the figure, it is a schematic diagram of the sampling needle aspiration process. Because the air pressure inside the sampling needle is already negative before the sampling needle enters the sample to be tested in the sample container, the air pressure inside the sampling needle is less than the first atmospheric pressure from the moment the air pressure inside the sampling needle becomes negative until the sampling needle moves to the sample aspiration position. Therefore, before the sampling needle aspirates the sample to be tested, a small amount of air is first sucked into the sampling needle. The sample to be tested aspirated by the sampling needle is then isolated from the pipeline liquid in the sample aspiration pipeline by this small amount of air, thereby preventing the pipeline liquid from affecting the accuracy of the sampling needle aspiration.

[0054] Furthermore, controlling the sampling needle to perform the sample-discharging action specifically includes: controlling the power source used to provide power to the sampling needle to provide a preset value of positive air pressure into the sampling needle, so that the sampling needle can discharge all the absorbed samples to be tested, and will not discharge the small section of air in the sampling pipeline into the sample container.

[0055] In some embodiments, in S08: after the sample-discharging action is completed, controlling the sampling needle to return to perform the sample-sucking action specifically includes: after the sample-discharging action is completed, controlling the sampling needle to move from its current position to a preset sample-sucking position before performing the sample-sucking action. In this embodiment, after the sampling needle completes the sample-discharging action, rather than controlling the sampling needle to directly perform the sample-sucking action at its current position after the sample-discharging action, it is necessary to first control the sampling needle to move from its current position to a preset sample-sucking position before performing the sample-sucking action. This prevents the sampling needle from performing the sample-sucking action again in an area where the original sample-sucking position may contain sample clots or debris, thereby re-absorbing an abnormal amount of sample.

[0056] In some embodiments, controlling the sampling needle to move from the current position to the preset sample aspiration position specifically includes controlling the sampling needle to move along the first direction to the preset sample aspiration position, that is, the preset sample aspiration position is located below the current position.

[0057] In some embodiments, controlling the sampling needle to move from the current position to the preset sample aspiration position specifically includes controlling the sampling needle to move along the second direction to the preset sample aspiration position, that is, the preset sample aspiration position is located above the current position.

[0058] In some embodiments, controlling the sampling needle to move from the current position to the preset sample aspiration position specifically includes controlling the sampling needle to move along the third direction perpendicular to the first direction to the preset sample aspiration position, that is, the preset sample aspiration position is located to the left of the current position.

[0059] In some embodiments, controlling the sampling needle to move from the current position to the preset sample aspiration position specifically includes controlling the sampling needle to move along the fourth direction opposite to the third direction to the preset sample aspiration position, that is, the preset sample aspiration position is located to the right of the current position.

[0060] See also Figure 4 , which is a flow chart of a sampling control method provided according to some embodiments of the present application. In this embodiment, after S08, S09 is further included.

[0061] S09: Determine the cumulative number of times the sampling needle has completed the sample aspirating action. If it is determined that the sample aspirated amount of the sampling needle is still abnormal and the cumulative number of times reaches a threshold, report a fault alarm message.

[0062] Generally, after the cumulative number reaches two, if it is still determined that the sampling needle's sample aspiration volume is still abnormal, it indicates that there is a high probability of a storage failure in the sampling device, and a fault alarm message is reported to remind the maintenance personnel to perform maintenance. In other embodiments, the sampling control method further includes controlling a cleaning device to perform a cleaning process on the sampling needle based on the fault alarm message, and after the cleaning process is completed, controlling the sampling needle to perform the sampling task.

[0063] See also Figure 5 As shown, it is a structural diagram of a sampling control device provided according to some embodiments of the present application. In this embodiment, the sampling control device includes a determination module 501, a first control module 502 and a second control module 503. The determination module 501 is used to determine whether the sample aspirated amount of the sampling needle is a normal sample aspirated amount after the sampling needle completes the current sample aspirating action. The first control module 502 is used to control the sampling needle to be removed from the sample container when determining whether the sample aspirated amount of the sampling needle is a normal sample aspirated amount, and move the sampling needle to the sample dripping position for sample dripping. The second control module 503 is used to control the sampling needle to perform a sample spitting action when determining whether the sample aspirated amount of the sampling needle is a normal sample aspirating amount, and after the sampling needle completes the sample spitting action, control the sampling needle to return to perform the sample aspirating action. The sample control device can achieve the same technical effect as the sample control method provided in the aforementioned embodiment. To avoid repetition, it will not be described here.

[0064] In some embodiments, the sampling control device further includes an alarm control module ( Figure 5 (not shown), the alarm control module is used to determine the cumulative number of times the sampling needle has completed the sample aspiration action. If it is determined that the sample aspiration amount of the sampling needle is still an abnormal sample aspiration amount and the cumulative number reaches a threshold, a fault alarm message is reported.

[0065] See also Figure 6 , which is a schematic diagram of the structure of a sampling device provided according to an embodiment of the present application. In this embodiment, the sampling device includes a processor 61 and a memory 62. The memory 62 stores a computer program executable by the processor. When the computer program is executed by the processor, it implements the sampling control method described in any embodiment of the present application. The sampling device and the sampling control method provided in the aforementioned embodiments can achieve the same technical effects. To avoid repetition, they are not described here.

[0066] See also Figure 7As shown, it is a schematic diagram of the structure of a sampling device provided according to some other embodiments of the present application, wherein the sampling device is used to sample the sample to be tested in the sample container 5. The sampling device includes a sampling controller ( Figure 7 ), a sampling needle 1, and a sample aspiration detection component 2. The sample aspiration detection component 2 is connected to the sampling controller and the sampling needle 1, respectively, and is used to detect the characteristic parameter of the sampling needle after the sampling needle 1 completes the current sample aspiration action, obtain the characteristic value after the sample aspiration, and send the characteristic value after the sample aspiration to the sampling controller.

[0067] Please continue to refer to Figure 7 As shown, in some embodiments, the sampling device further includes a sampling pipeline 3 and a power source 4. The sampling needle 1 is connected to the power source 4 through the sampling pipeline 3, and the sample aspiration detection component 2 is disposed on the sampling pipeline 3 to be connected to the sampling needle 1 through the sampling pipeline 3. The power source 4 is connected to the sampling controller and is configured to, under the control of the sampling controller, deliver negative air pressure to the sampling needle 1 through the sampling pipeline 3 when the sampling needle 1 needs to aspirate a sample, and deliver positive air pressure to the sampling needle through the sampling pipeline 3 when the sampling needle 1 needs to spit out a sample.

[0068] In some embodiments, the sample suction detection component 2 is a pressure detection component, such as a pressure sensor.

[0069] In some embodiments, the sample suction detection component 2 is a detection component, and the liquid level detection component is, for example, an optical coupler disposed above the sample container 5 .

[0070] See also Figure 8 As shown, it is a flow chart of the method for the sampling device provided in accordance with an embodiment of the present application to perform a sampling task. The sampling device first performs a first sampling action on the sample to be tested in the sample container, and then performs a sampling volume detection to determine whether the sampling volume after the sampling needle performs the first sampling action is normal. If it is determined that the first sampling volume of the sampling needle is a normal sampling volume, the sampling device completes the current sampling task according to the normal process. If it is determined that the first sampling volume is an abnormal sampling volume, the sampling needle performs a sample spitting action. After the sample spitting is completed, the sampling needle performs a second sampling action, that is, the sampling needle returns to perform the sampling action. After the sampling needle completes the second sampling action, the sampling volume of the second sampling of the sampling needle continues to be checked. If it is determined that the sampling volume of the second sampling of the sampling needle is a normal sampling volume, the sampling device completes the current sampling task according to the normal process. If it is determined that the sampling volume of the second sampling of the sampling needle is still an abnormal sampling volume, the system where the sampling device is located will alarm, and the cleaning device in the system will perform a cleaning process on the sampling needle.

[0071] A sample analyzer comprises a detection and analysis device and the sampling equipment as described above, wherein the detection and analysis device performs detection and analysis on a sample to be tested collected by the sampling equipment to obtain detection and analysis data of the sample to be tested.

[0072] A computer-readable storage medium stores a computer program, and when the computer program is executed by a control device, the sampling control method as described above is implemented.

[0073] As can be seen from the above, the sampling device provided by the present application determines whether the current sample aspiration volume of the sampling needle is a normal sample aspiration volume based on the post-sampling characteristic value of the sampling needle's characteristic parameter after the sampling needle completes the sample aspiration action during the execution of the current sampling task. If the sample aspiration volume of the sampling needle is determined to be a normal sample aspiration volume, the sampling needle is removed from the sample container and moved to the sample dripping position to drip the sample, thereby completing the current sampling task. Otherwise, the sampling needle performs the sample spitting action, and after the sampling needle completes the sample spitting action, it returns to perform the sample aspiration action, i.e., re-executes the sample aspiration action in the current sampling task. Therefore, the sampling device has a high sample aspiration accuracy and can reduce equipment maintenance time.

[0074] In addition, in some embodiments, the present application also provides a sample analyzer, which includes the sampling device provided according to any embodiment of the present application and a detection and analysis device connected to the sampling device, and the detection and analysis device performs detection and analysis based on the sample to be tested collected by the sampling device to obtain detection and analysis data of the sample to be tested.

[0075] The present application also provides a computer-readable storage medium having a computer program stored thereon. When the computer program is executed by a processor, the various processes of the above-mentioned sampling control method embodiment are implemented, and the same technical effects are achieved. To avoid repetition, the details are not described here. The computer-readable storage medium is, for example, a read-only memory (ROM), a random access memory (RAM), a magnetic disk, or an optical disk.

[0076] The above description is merely a specific embodiment of the present application, but the scope of protection of the present application is not limited thereto. Any modifications or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in the present application should be included in the scope of protection of the present application. Therefore, the scope of protection of the present application should be based on the scope of protection of the claims.

Claims

1. A sampling control method, characterized in that: include: In the process of controlling the sampling needle to perform the current sampling task, after the sampling needle completes the sample aspiration action, obtaining a post-sampling characteristic value of a characteristic parameter of the sampling needle, wherein the characteristic parameter is a parameter associated with the sample aspiration amount of the sampling needle; Determining whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount according to the characteristic value after the sample aspirated; If so, the sampling needle is controlled to be removed from the sample container, and the sampling needle is moved to the sample dripping position to drip the sample, thereby completing the current sampling task; If not, the sampling needle is controlled to perform the sample-discharging action, and after the sampling needle completes the sample-discharging action, the sampling needle is controlled to return to perform the sample-sucking action.

2. The sampling control method according to claim 1, characterized in that: The determining, based on the characteristic value after the sample aspiration, whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount comprises: Whether the sample aspirated amount of the sampling needle is abnormal is determined based on the difference between the characteristic value after sample aspirating and the characteristic value before sample aspirating, wherein the characteristic value before sample aspirating is the value corresponding to the characteristic parameter before the sampling needle performs the current sample aspirating action.

3. The sampling control method according to claim 2, characterized in that: Before determining whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount, the method further includes: Before controlling the sampling needle to perform a sample aspiration action, the characteristic parameter in the sampling needle is acquired, and a characteristic value before sample aspiration corresponding to the characteristic parameter is obtained.

4. The sampling control method according to claim 2, characterized in that: The characteristic variable is the pressure in the sampling needle.

5. The sampling control method according to claim 2, characterized in that: The characteristic parameter is the liquid level height of the sample to be tested in the sampling needle.

6. The sampling control method according to claim 1, characterized in that: The controlling the sampling needle to perform the sample spitting action includes: A power source connected to the sampling needle is controlled to output positive air pressure to the sampling needle, so that the pressure in the sampling needle is in a positive air pressure state, so as to spit out the sample to be tested sucked by the sampling needle into the sample container.

7. The sampling control method according to claim 1, characterized in that: Also includes: In the process of controlling the sampling needle to move toward the current suction position, before the needle head of the sampling needle moves into the sample to be tested in the sample container, the pressure in the sampling needle is controlled to be in a negative pressure state.

8. The sampling control method according to claim 1, characterized in that: After controlling the sampling needle to return and perform the sample aspirating action, the sampling control method further includes: The cumulative number of times the sampling needle has completed the sample aspirating action is determined. If it is determined that the sample aspirated amount of the sampling needle is still an abnormal sample aspirated amount and the cumulative number reaches a threshold, a fault alarm message is reported.

9. The sampling control method according to claim 8, characterized in that: Also includes: According to the fault alarm information, the cleaning device is controlled to perform a cleaning process on the sampling needle.

10. The sampling control method according to claim 1, characterized in that: After the sample spitting action is completed, controlling the sampling needle to return to perform the sample aspirating action includes: After the sample-discharging action is completed, the sampling needle is controlled to move from the current position to the preset sample-sucking position, and then the sample-sucking action is performed.

11. A sampling control device, characterized in that: include: A determination module, configured to determine whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount after the sampling needle completes the current sample aspirating action; a first control module configured to control the sampling needle to be removed from the sample container and to move the sampling needle to a sample dropping position for sample dropping when determining whether the sample aspirated amount by the sampling needle is a normal sample aspirated amount; The second control module is used to control the sampling needle to perform a sample discharge action when determining whether the sample aspirated amount of the sampling needle is a normal sample aspirated amount, and control the sampling needle to return to perform the sample aspirating action after the sampling needle completes the sample discharge action.

12. A sampling device, characterized in that: The method comprises a processor and a memory, wherein the memory stores a computer program executable by the processor, and when the computer program is executed by the processor, the sampling control method according to any one of claims 1 to 10 is implemented.

13. A sampling device, characterized in that: comprising a sampling controller, a sampling needle, and a sample aspiration detection component for implementing the sampling control method according to any one of claims 1 to 10; The sample aspiration detection component is connected to the sampling controller and the sampling needle respectively, and is used to detect the characteristic parameters of the sampling needle after the sampling needle completes the current sample aspiration action, obtain the characteristic value after sample aspiration, and send the characteristic value after sample aspiration to the sampling controller.

14. The sampling device according to claim 13, characterized in that It also includes sampling lines and power sources; The sampling needle is connected to the power source through the sampling pipeline, and the sample suction detection component is arranged on the sampling pipeline to be connected to the sampling needle through the sampling pipeline; The power source is connected to the sampling controller and is used to deliver negative air pressure to the sampling needle through the sampling pipeline when the sampling needle needs to perform a sample aspiration action, and to deliver positive air pressure to the sampling needle through the sampling pipeline when the sampling needle needs to perform a sample spitting action, according to the control of the sampling controller.

15. The sampling device according to claim 13, characterized in that The sample suction detection component is a pressure detection component or a liquid level detection component.

16. A sample analyzer, characterized in that: It comprises a detection and analysis device and the sampling equipment according to any one of claims 12 to 15, wherein the detection and analysis device performs detection and analysis on the sample to be tested collected by the sampling equipment to obtain detection and analysis data of the sample to be tested.

17. A computer-readable storage medium, characterized in that The computer-readable storage medium stores a computer program, and when the computer program is executed by a control device, the sampling control method according to any one of claims 1 to 10 is implemented.

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