An oil-control acne-removing composition, its preparation method and use

Abstract

The present application belongs to the technical field of cosmetics, and discloses an oil-controlling and acne-removing composition, a preparation method and application thereof. The oil-controlling and acne-removing composition comprises the following components: aloe vera ferment, nicotinamide and / or panthenol, trehalose and / or xylitol, quaternary ammonium salt-73 and lysophospholipid. The components of the oil-controlling and acne-removing composition of the present application play a synergistic role, promote the penetration of the efficacy components, have excellent oil-controlling and acne-removing effects, can not only reduce sebum secretion, soften hair follicle plugs, reduce the number of excessive propionibacterium acnes and relieve inflammation, but also keep moisturizing without dryness, are mild without irritation, can fade acne marks and promote the repair of damaged barriers.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of cosmetics, and particularly relates to an oil-controlling and acne-removing composition as well as a preparation method and application thereof. BACKGROUND

[0002] The sebaceous glands of oily skin have relatively strong secretion function, and the face is often greasy, which has an oil light that affects the appearance and may cause large pores, dull skin, and oily skin is more susceptible to microbial invasion and some corresponding skin diseases, such as acne vulgaris or seborrheic dermatitis. Therefore, controlling the secretion of sebaceous glands, reducing oil secretion and thereby inhibiting the occurrence of acne are the key to maintaining the health and appearance of oily skin.

[0003] At present, there are many methods for reducing the skin surface sebum on the market, but most of them are in the form of "treating the symptoms" to remove or adsorb excess sebum, and cannot truly control the secretion of sebum. For example, Chinese patent CN202110809211.X discloses a glacial rock cleaning oil-controlling mud film and a preparation method thereof, which uses Canadian bentonite 10-30 parts, sea sludge 2-6 parts, bentonite 10-20 parts, kaolin 5-10 parts and the like to remove excess sebum on the face, but cannot reduce the secretion of skin sebum. Some products excessively use cleaning products and exfoliating products such as alpha-hydroxy acids and salicylic acid in order to pursue cleaning effect, which not only damages the skin barrier, but also may even stimulate the excessive secretion of sebaceous glands.

[0004] Therefore, it is necessary to develop a mild and non-irritating product that can effectively control oil and remove acne. SUMMARY

[0005] The present application aims to at least solve one of the technical problems existing in the prior art. To this end, the present application provides an oil-controlling and acne-removing composition, a preparation method and application thereof, which is mild and non-irritating and has excellent oil-controlling and acne-removing efficacy.

[0006] The present application provides an oil-controlling and acne-removing composition in the first aspect, which comprises the following components: aloe vera ferment, nicotinamide and / or panthenol, trehalose and / or xylitol, quaternary ammonium salt-73 and lysophospholipid.

[0007] In the oil-controlling and acne-removing composition of the present application, the efficacy of each component is as follows:

[0008] The aloe fermentation product contains small molecule polysaccharides, organic acids and other components, which can not only improve skin moisture but also soften keratin and dredge blocked pores; the weak acid system (pH 3.5-4.5) of the aloe fermentation product can adjust the pH value of the skin and promote the penetration of effective components; the aloe fermentation product of the present application is aloe gel obtained after peeling fresh aloe, which is subjected to high-pressure homogenization and then fermented by lactic acid bacteria and yeast, and the supernatant obtained by separation can be provided by Guangzhou Nuowei Biological Technology Co., Ltd.

[0009] Nicotinamide as a whitening agent component can inhibit the transfer of melanin in the skin and fade the pigmentation caused by acne; in addition, nicotinamide can also inhibit the secretion of sebum from sebaceous glands, thereby playing an oil control role.

[0010] Panthenol as a moisturizing agent has good soothing and repairing effects and can promote the repair of damaged barrier; in addition, panthenol can also inhibit the secretion of sebaceous glands.

[0011] Trehalose and xylitol are both natural and mild moisturizing agents, which have good moisturizing, nourishing and skin care effects and can also be used as prebiotic components to regulate the balance of skin microecology.

[0012] Quaternary ammonium salt-73 has strong antibacterial activity and can quickly and persistently reduce the number of pathogenic bacteria such as Propionibacterium acnes and Staphylococcus aureus, has significant anti-acne and anti-inflammatory effects, and can also effectively inhibit the formation of melanin.

[0013] Lecithin is a good emulsifying agent, which can improve the permeability of the skin and also repair damaged epidermal cells and accelerate skin metabolism.

[0014] The present application comprehensively considers the characteristics of oily skin and the links of acne occurrence, and reasonably and synergistically compounding the above-mentioned components, which can not only reduce sebum secretion, soften hair follicle plugs, reduce the number of excessive Propionibacterium acnes and relieve inflammation, but also fade acne marks and promote the repair of damaged barrier. The combination mode of the present application can also effectively promote penetration and absorption, wherein the aloe fermentation product and the moisturizing agents (panthenol, trehalose and xylitol) can increase the hydration degree of the skin and reduce the pH value of the skin, which is helpful to improve the penetration rate of active substances (nicotinamide and quaternary ammonium salt-73); the solubility of quaternary ammonium salt-73 is poor, and the amphiphilic property of small molecule lecithin can improve the transdermal effect of quaternary ammonium salt-73, effectively kill pathogenic bacteria, and is different from the traditional penetration-promoting component (azone) which destroys the structure of the stratum corneum of the skin. The oil control and acne-removing composition of the present application is mild and non-irritating, the various components are effectively synergistic, has excellent oil control and acne-removing effects, can also promote the rapid repair of damaged skin, and fade acne marks.

[0015] According to some embodiments of the present application, the oil-control and acne-removing composition comprises, by mass fraction, the following components: aloe fermentation 10-99 parts, nicotinamide and / or panthenol 1-20 parts, trehalose and / or xylitol 0.1-5 parts, quaternary ammonium salt-73 0.0005-0.05 parts, and lysophospholipid 0.001-0.50 parts.

[0016] According to some embodiments of the present application, the oil-control and acne-removing composition comprises, by mass fraction, the following components: quaternary ammonium salt-73 0.005-0.05 parts, lysophospholipid 0.05-0.5 parts, xylitol 1-3 parts, panthenol 1-5 parts, nicotinamide 1-5 parts, and aloe fermentation 80-95 parts.

[0017] According to some embodiments of the present application, the oil-control and acne-removing composition comprises, by mass fraction, the following components: quaternary ammonium salt-73 0.001-0.01 parts, lysophospholipid 0.01-0.1 parts, trehalose 0.1-1 parts, panthenol 1-10 parts, and aloe fermentation 90-99 parts.

[0018] According to some embodiments of the present application, the oil-control and acne-removing composition comprises, by mass fraction, the following components: quaternary ammonium salt-73 0.001-0.005 parts, lysophospholipid 0.01-0.05 parts, trehalose 0.1-1 parts, nicotinamide 5-10 parts, and aloe fermentation 80-95 parts.

[0019] The second aspect of the present application provides a preparation method of the oil-control and acne-removing composition according to the present application, comprising the following steps:

[0020] The components are mixed and stirred uniformly to obtain the oil-control and acne-removing composition.

[0021] According to some embodiments of the present application, the preparation method of the oil-control and acne-removing composition comprises the following steps:

[0022] 1) Quaternary ammonium salt-73 is dissolved in an appropriate amount of polyol in advance, heated to 85-90℃ until completely dissolved to obtain mixture A;

[0023] 2) Lysophospholipid is dispersed and dissolved in an appropriate amount of polyol in advance, and after mixture A of step 1) is cooled to 70-80℃, it is slowly added dropwise into the lysophospholipid dispersion, and homogenized at 6000-9000 r / min, the homogenization time is controlled at 3-5 min to obtain mixture B;

[0024] 3) After mixture B of step 2) is cooled to below 40℃, nicotinamide and / or panthenol, trehalose and / or xylitol are added into the aloe fermentation, and stirred until dissolved uniformly to obtain the oil-control and acne-removing composition.

[0025] According to some embodiments of the present application, the polyol includes at least one of glycerol, butanediol, 1,2-pentanediol, 1,3-propanediol and 1,2-hexanediol. The use of polyol as an auxiliary solvent can further improve the solubility of quaternary ammonium salt-73 and lysophosphatidylcholine and the stability of the overall composition.

[0026] According to some embodiments of the present application, the mass ratio of the quaternary ammonium salt-73 and the polyol is 1:(1-10); the mass ratio of the lysophosphatidylcholine and the polyol is 1:(1-10).

[0027] The third aspect of the present application provides a cosmetic product comprising the oil-controlling and acne-removing composition of the present application.

[0028] According to some embodiments of the present application, the oil-controlling and acne-removing composition is added in an amount of 1-50 wt%.

[0029] According to some embodiments of the present application, the oil-controlling and acne-removing composition is added in an amount of 5-20 wt%.

[0030] According to some embodiments of the present application, the dosage form of the cosmetic product is selected from any one of a cream, a lotion, an emulsion, a gel, a mask or a wash.

[0031] Compared with the prior art, the present application has the following advantages:

[0032] The components of the oil-controlling and acne-removing composition of the present application work synergistically to promote the penetration of the functional ingredients, have excellent oil-controlling and acne-removing effects, can not only reduce sebum secretion, soften hair follicle plugs, reduce the number of excess Propionibacterium acnes and alleviate inflammation, but also moisturize without drying, are mild without irritation, can fade acne marks and promote the repair of damaged barrier. BRIEF DESCRIPTION OF DRAWINGS

[0033] The present application will be further described below in conjunction with the drawings and examples.

[0034] Figure 1 is the picture taken by the instrument before and after the subject uses the product. DETAILED DESCRIPTION

[0035] The content of the present application will be further described in detail below through specific examples. The raw materials, reagents or devices used in the examples, unless otherwise specified, can be obtained from conventional commercial channels or can be obtained by existing technical methods. Unless otherwise specified, the test or test method is a conventional method in the art.

[0036] Example 1

[0037] An oil-controlling and acne-removing composition includes the following components in mass fraction:

[0038] Quaternary ammonium salt-73 0.05 parts, lysophospholipid 0.5 parts, xylitol 1 part, nicotinamide 2 parts and aloe fermentation 96.45 parts.

[0039] The preparation method of the above oil-controlling and acne-removing composition is as follows:

[0040] 1) Dissolve quaternary ammonium salt-73 in auxiliary solvent butanediol in advance, heat to 85°C to completely dissolve, and obtain mixture A; the mass ratio of quaternary ammonium salt-73 and butanediol is 1:1;

[0041] 2) Dissolve lysophospholipid in auxiliary solvent glycerol in advance, and slowly drop mixture A of step 1) into the lysophospholipid dispersion liquid after mixture A is cooled to 70°C, and homogenize at 6000 r / min, and the homogenization time is controlled to be 3 min, to obtain mixture B; the mass ratio of lysophospholipid and glycerol is 1:1;

[0042] 3) After mixture B of step 2) is cooled to 40°C, nicotinamide and xylitol are added into aloe fermentation, and stirred until dissolved uniformly.

[0043] Example 2

[0044] An oil-controlling and acne-removing composition comprises the following components in mass fraction:

[0045] Quaternary ammonium salt-73 0.01 parts, lysophospholipid 0.1 parts, trehalose 0.5 parts, panthenol 10 parts and aloe fermentation 89.39 parts.

[0046] The preparation method of the above oil-controlling and acne-removing composition is the same as that of example 1.

[0047] Example 3

[0048] An oil-controlling and acne-removing composition comprises the following components in mass fraction:

[0049] Quaternary ammonium salt-73 0.002 parts, lysophospholipid 0.02 parts, trehalose 1 part, nicotinamide 10 parts and aloe fermentation 88.978 parts.

[0050] The preparation method of the above oil-controlling and acne-removing composition is the same as that of example 1.

[0051] Example 4

[0052] An oil-controlling and acne-removing composition comprises the following components in mass fraction:

[0053] Quaternary ammonium salt-73 0.0005 parts, lysophospholipid 0.001 parts, trehalose 0.1 parts, nicotinamide 1 part and aloe fermentation 98.8985 parts.

[0054] The oil-control acne-removing composition is prepared by the same method as in Example 1.

[0055] Example 5

[0056] An oil-control acne-removing composition includes the following components in mass parts:

[0057] Quaternary ammonium salt-73 0.05 parts, lysophospholipid 0.5 parts, trehalose 2.5 parts, xylitol 2.5 parts, nicotinamide 10 parts, panthenol 10 parts, and aloe fermentation product 74.45 parts.

[0058] The oil-control acne-removing composition is prepared by the same method as in Example 1.

[0059] Example 6

[0060] An oil-control acne-removing composition includes the following components in mass parts:

[0061] Quaternary ammonium salt-73 0.025 parts, lysophospholipid 0.25, trehalose 1.25 parts, xylitol 1.25 parts, nicotinamide 5 parts, panthenol 5 parts, and aloe fermentation product 87.225 parts.

[0062] The oil-control acne-removing composition is prepared by the same method as in Example 1.

[0063] Comparative Example 1

[0064] Comparative Example 1 replaces quaternary ammonium salt-73 with deionized water, and the other components, the amounts of addition, and the preparation method are the same as in Example 1.

[0065] Comparative Example 2

[0066] Comparative Example 2 replaces lysophospholipid with deionized water, and the other components, the amounts of addition, and the preparation method are the same as in Example 1.

[0067] Comparative Example 3

[0068] Comparative Example 3 replaces xylitol with deionized water, and the other components, the amounts of addition, and the preparation method are the same as in Example 1.

[0069] Comparative Example 4

[0070] Comparative Example 4 replaces nicotinamide with deionized water, and the other components, the amounts of addition, and the preparation method are the same as in Example 1.

[0071] Comparative Example 5

[0072] Comparative Example 5 replaces aloe fermentation product with deionized water, and the other components, the amounts of addition, and the preparation method are the same as in Example 1.

[0073] Comparative Example 6

[0074] Comparative Example 6 replaces quaternary ammonium salt-73 with salicylic acid, other components, additive amounts and preparation methods are the same as Example 1.

[0075] Comparative Example 7

[0076] Comparative Example 7 replaces lyso- lecithin with azone, other components, additive amounts and preparation methods are the same as Example 1.

[0077] Comparative Example 8

[0078] Comparative Example 8 replaces xylitol with glycerol, other components, additive amounts and preparation methods are the same as Example 1.

[0079] Comparative Example 9

[0080] Comparative Example 9 replaces nicotinamide with Ulmus davidiana var. japonica extract, other components, additive amounts and preparation methods are the same as Example 1.

[0081] Comparative Example 10

[0082] Comparative Example 10 replaces aloe fermentation product with aloe leaf water, other components, additive amounts and preparation methods are the same as Example 1.

[0083] Comparative Example 11

[0084] Comparative Example 11 replaces quaternary ammonium salt-73 with salicylic acid, replaces lyso- lecithin with azone, replaces xylitol with glycerol, replaces nicotinamide with Ulmus davidiana var. japonica extract, replaces aloe fermentation product with aloe leaf water, component additive amounts and preparation methods are the same as Example 1.

[0085] Application Example 1

[0086] An oil-control acne lotion, the formula is shown in Table 1.

[0087] Table 1 Formula Table

[0088]

[0089] The preparation method of the oil-control acne lotion, comprising the following steps:

[0090] 1) Put the A component into the water phase pot, stir at 80℃ until completely dissolved;

[0091] 2) Put the B component into the oil phase pot, stir at 80℃ until completely dissolved, slowly extract oil emulsion, high-speed homogenization for 15min, cool down;

[0092] 3) At 60°C, add C component, stir until evenly dispersed, reduce to 40°C, add D component, stir until evenly dispersed.

[0093] Application Examples 2-6

[0094] In comparison with Application Example 1, in Application Examples 2-6, the oil-control acne-removing composition of Example 1 is replaced by the oil-control acne-removing composition of Examples 2-6 respectively, and other conditions are the same as those of Application Example 1.

[0095] Application Comparative Examples 1-11

[0096] In comparison with Application Example 1, in Application Comparative Examples 1-11, the oil-control acne-removing composition of Example 1 is replaced by the oil-control acne-removing composition of Comparative Examples 1-11 respectively, and other conditions are the same as those of Application Example 1.

[0097] Experimental Example 1 Penetration Model Test

[0098] 1.1 Experimental Method

[0099] Franz vertical double-chamber penetration diffusion cell is used for the experiment, the effective penetration area is 1.77 cm 2 , the receiving chamber volume is 12 mL, and 30% ethanol PBS buffer salt solution is used as the receiving liquid. The prepared isolated pig skin is placed between the two half cells of the diffusion chamber and the receiving chamber of the Franz vertical diffusion cell, and is fixed with a clamp. The skin horny layer is upward, 0.1 g of each sample is placed in the diffusion chamber, the receiving chamber is filled with receiving liquid, and the liquid surface is just in contact with the skin. The air bubbles in the receiving medium are removed, the constant temperature water bath is heated, and the water bath temperature is set to (32±0.5)℃. The magnetic stirrer is started, and the stirring speed is constant (300 r / min). At 2, 4, 8, 10 and 24 h, 0.9 mL of receiving liquid is taken each time, and after each sampling, 0.9 mL of blank receiving liquid at the same temperature is immediately added. The concentration of the test component in the receiving liquid at different time periods is determined by HPLC-DAD method. The data is processed according to the following formula to obtain the cumulative penetration amount.

[0100] Cumulative penetration amount Q calculation formula: Q=[Cn×V+∑Ci×V0] / S (i=1···n-1);

[0101] Q: cumulative penetration amount; V: receiving liquid volume in the receiving chamber; V0: volume of each sampling; Ci: drug concentration in the receiving liquid from the first sampling to the last sampling; Cn: sample concentration measured at the nth sampling point.

[0102] 1.2 Experimental Results

[0103] The test results are shown in Table 2.

[0104] Table 2 Cumulative penetration amount of quaternary ammonium salt-73 (unit: μg / cm2

[0105]

[0106]

[0107] Quaternary ammonium salt-73 is the key component for acne removal in the composition, but it has poor solubility, is easy to precipitate, and has low bioavailability. The present application can effectively promote the penetration effect of quaternary ammonium salt-73 by reasonably compounding it with other components. The data in Table 2 show that Example 1 has the best penetration-promoting effect, and lysophospholipid is the main factor for promoting the penetration of quaternary ammonium salt-73, because lysophospholipid has small molecules and high affinity with skin cells; aloe ferment can promote the penetration of quaternary ammonium salt-73 by increasing skin hydration and the low pH value (pH 3.5-4.5); xylitol moisturizing agent can also increase the skin moisture content and promote penetration and absorption. The penetration-promoting effect of the present application is significantly better than that of traditional penetration-promoting agent azone through the combined action of multiple specific components.

[0108] Experimental Example 2: Oil control and acne mark removal test

[0109] 2.1 Experimental method

[0110] 54 people aged 18 to 45 with oily and acne skin were recruited, and the subjects used the product on their faces in the morning and evening, respectively. Before and after using the product for 7 days, under the conditions of temperature 20±2℃ and humidity 50±10%, the subjects measured the oil content on their faces after cleaning their faces for 20 minutes, and used CL400 skin color tester to test, and comprehensively evaluated the oil control and acne mark removal effect of the product on human skin.

[0111] The subjects used CL400 skin color tester to measure the L* value and a* value of the facial skin to evaluate the acne mark removal effect of the composition. The larger the L* value, the whiter the skin color, and the better the acne mark recovery; the smaller the a* value, the lighter the skin redness, and the better the acne mark recovery.

[0112] 2.2 Experimental results

[0113] The test results are shown in Table 3 and Table 4.

[0114] Table 3: Oil control test results

[0115]

[0116]

[0117] Table 4: Acne mark removal test results

[0118]

[0119] ​

[0120] Note that the blank control refers to removing the oil-controlling acne-removing composition of Example 1 based on the application of Example 1. The oil change rate refers to the change rate of the skin oil content after using the product compared to before using the product (a positive value indicates an increase in oil content, and a negative value indicates a decrease in oil content).

[0121] Table 3 data shows that nicotinamide and panthenol are key ingredients for regulating the oil secretion of sebaceous glands, and weakly acidic aloe ferment also helps to soften keratin and unblock clogged pores, helping the discharge of sebum, and helping to clean the skin. The acne-removing effectiveness of the skin and the degree of regulation of the oil of the skin have a certain correlation, and the content of quaternary ammonium salt-73 is also significantly related. The composition of the application has better therapeutic effect on oil control; when any one component is missing in the composition, or the component is replaced by other similar components, the efficacy will be reduced.

[0122] Table 4 data shows that nicotinamide in the composition is a key component for improving post-acne pigmentation, nicotinamide regulates oil secretion while also having certain anti-inflammatory effect, and also as a whitening agent, can significantly inhibit the transfer of melanin; quaternary ammonium salt-73 and aloe ferment can also fade the deposition of pigments to some extent. Aloe ferment and panthenol have good anti-inflammatory and repair effects, can soothe redness and fade acne marks. The composition of the application has obvious effect in fading acne marks and promoting repair after reasonable compounding of various components; when any one component is missing in the composition, or the component is replaced by other similar components, the efficacy will be reduced.

[0123] Experimental Example 3 Acne-removing Test

[0124] Based on time and cost considerations, the product of application example 3 among them was selected to carry out the following test.

[0125] 3.1 Experimental method

[0126] Thirty-three people with oily and acne-prone skin aged 18 to 45 were recruited, and the subjects used the product on their faces in the morning and evening, before and after using it for 7 days, under the conditions of temperature 20±2℃ and humidity 50±10%, the subjects cleaned their faces and waited for 20min, then through the way of questionnaire and using VISIA instrument to take pictures, the acne-removing effect of the product on human skin was comprehensively evaluated.

[0127] 3.2 Experimental results

[0128] The test results are shown in Table 5 and Figure 1 .

[0129] Table 5 Acne-removing test results

[0130]

[0131] It should be noted that the effective rate ≥ 50% can be considered as the product effective, and the effective rate = (obvious + very obvious) number of people / total number of people.

[0132] The data in Table 5 shows that after 7 days of use, 84.85% of the subjects recognized that the product has acne-removing effect.

[0133] Figure 1 The instrument photographed pictures of a subject who believed that there was obvious acne-removing effect before using the product (D0) and after using the product for 7 days (D7). According to the evaluation criteria, the acne-removing effect was evaluated as follows: Figure 1 It is shown that before using the product, the acne part presents a red and swollen inflammatory state, and after using the product for 7 days, it has been obviously improved and basically recovered. At the same time, the acne marks on other parts of the face also have a certain degree of fading, and the whole facial area presents a whole brightening effect. During this period, the user also did not appear a serious acne recurrence phenomenon, which indicates that the oil-controlling and acne-removing composition of the application has a good conditioning effect on oily and acne skin.

[0134] In summary, the above experimental results show that the composition of the application, by reasonably compounding aloe ferment, nicotinamide and / or panthenol, trehalose and / or xylitol, quaternary ammonium salt-73 and lysophospholipid, has mild and non-irritating properties, plays a synergistic effect among multiple components, has excellent oil-controlling and acne-removing effect, and can also promote the rapid repair of damaged skin and fade acne marks.

[0135] The preferred embodiments of the application are specifically described above, but the application is not limited to the described embodiments, and those skilled in the art can make various equivalent modifications or replacements without departing from the spirit of the application. These equivalent modifications or replacements are all included in the scope defined by the claims of the present application.

Claims

1. An oil control acne composition characterized in that, The oil-control and acne-removing composition comprises, by mass fraction, 10-99 parts of aloe fermentation, 1-20 parts of nicotinamide and / or panthenol, 0.1-5 parts of trehalose and / or xylitol, 0.0005-0.05 parts of quaternary ammonium salt-73, and 0.001-0.50 parts of lysophospholipid. The aloe fermentation is obtained by fermenting an aloe gel obtained by peeling an aloe with lactic acid bacteria and yeast after high-pressure homogenization.

2. The oil control acne-treating composition of claim 1, wherein The oil-control and acne-removing composition comprises, by mass fraction, 0.005-0.05 parts of quaternary ammonium salt-73, 0.05-0.5 parts of lysophospholipid, 1-3 parts of xylitol, 1-5 parts of panthenol, 1-5 parts of nicotinamide, and 80-95 parts of aloe fermentation.

3. The oil control acne-treating composition of claim 1, wherein The oil-control and acne-removing composition comprises, by mass fraction, 0.001-0.01 parts of quaternary ammonium salt-73, 0.01-0.1 parts of lysophospholipid, 0.1-1 parts of trehalose, 1-10 parts of panthenol, and 90-99 parts of aloe fermentation.

4. The oil control acne-treating composition of claim 1, wherein The oil-control and acne-removing composition comprises, by mass fraction, 0.001-0.005 parts of quaternary ammonium salt-73, 0.01-0.05 parts of lysophospholipid, 0.1-1 parts of trehalose, 5-10 parts of nicotinamide, and 80-95 parts of aloe fermentation.

5. A process for the preparation of the oil-control acne composition according to any one of claims 1 to 4, characterized in that, The method comprises the following steps: The components are mixed and stirred to obtain the oil-control and acne-removing composition.

6. A cosmetic product, characterized by, The oil-control and acne-removing composition of any one of claims 1-4.

7. The cosmetic product according to claim 6, characterized in that, The oil-control and acne-removing composition is added in an amount of 1-50 wt%.

8. The cosmetic product according to claim 7, characterized in that, The oil-control and acne-removing composition is added in an amount of 5-20 wt%.

9. The cosmetic product according to claim 6, characterized in that, The cosmetic is in any one of a cream, a lotion, an emulsion, a gel, a pack, or a wash.

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