Method for adjusting the range of a pipette, adjustment system and adjustment device

Abstract

The application provides a pipette range adjustment method, an adjustment system and an adjustment device. The adjustment method comprises the following steps: S1, determining an adjustment base R; S2, determining an adjustment direction D; S3, determining a rotation gear G; S4, determining a range adjustment multiple M based on the rotation gear; S5, determining an adjustment step S; S6, calculating a current single range adjustment value; and S7, calculating a cumulative range adjustment value. The adjustment system comprises a control component, a range adjustment component, a rotation interval time determination component, a rotation direction determination component and a range calculation component. The adjustment device comprises a display screen, a main shell, a magnetic code ring, a manual rotating part, a magnetic induction device and a main control board. The method can quickly and accurately adjust the range, realizes high-precision adjustment of a large range, and greatly improves the adjustment precision and the adjustment efficiency.

Description

Technical Field

[0001] This invention relates to the fields of biology, medicine, and communication technology, and specifically to a method, system, and device for adjusting the volume of a pipette. Background Technology

[0002] Pipettes are widely used in the life sciences, such as in the biological, pharmaceutical, and diagnostic industries. In recent years, laboratory instruments and equipment have begun to undergo digital upgrades, and as the most commonly used instrument in biological experiments, intelligent pipettes have entered the research and development stage and are ready for market.

[0003] Volume adjustment is a basic function of pipettes. Currently, manual pipettes on the market mainly use a combination of physical knobs and counters, while electric pipettes mainly use physical buttons, with some using a combination of touch screens and side rotary buttons.

[0004] Despite the existence of many solutions for adjusting the volume of pipettes, most of them have limitations. For example, physical knob adjustment is slow and inefficient, and there is a risk of button failure and poor tactile feedback. Touch control solutions for electric pipettes have the risk of accidental touch and require finding the settings in the system first, which is cumbersome.

[0005] Currently, intelligent pipettes have begun research and development and production. However, traditional physical buttons or knobs are difficult to record the volume setting and the pipetting operation at the set volume. In order to solve the user's need to quickly and accurately set the pipette volume, save time and effort, and avoid erroneous operation, and to realize the full process recording function of intelligent pipetting, an effective volume setting solution needs to be proposed. Summary of the Invention

[0006] To address the shortcomings of the prior art, the present invention aims to provide a pipette range adjustment method, system, and device that enables rapid and accurate range adjustment, achieving precision down to 0.1 μL per adjustment increment. This not only allows for quick pipette adjustment, saving time and effort, but also avoids accidental touches and other operational errors, improving the user experience. Furthermore, the present invention facilitates comprehensive recording of the pipetting process, promotes the upgrading of pipettes from manual to electric, and from electric to intelligent operation, and further facilitates process traceability and experimental data analysis for pipetting operations.

[0007] Specifically, in a first aspect, the present invention provides a method for adjusting the volume of a pipette, which specifically includes the following sub-steps:

[0008] S1. Determine the adjustment base. ;

[0009] S2. Determine the adjustment direction The adjustment direction is determined based on the rotation direction of the range adjustment component. When the adjustment direction is clockwise, The value is +1, and when the adjustment direction is counterclockwise, The value is -1; the specific method for determining the rotation direction of the range adjustment component is as follows: multiple magnetic signal generating devices are evenly arranged on the range adjustment component, which generate signals when rotating and are sensed by the signal sensing component. The rotation direction of the range adjustment component is determined according to the order of the signals sensed at both ends of the signal sensing component.

[0010] S3. Determine the rotation gear. Determine the rotation gear. , ,in For high-end, Mid-range For lower-end models, the specific steps include the following:

[0011] S31. Determine the rotation interval of the range adjustment component. The interval between signals generated by adjacent magnetic signal generators on the range adjustment assembly is the rotation interval of the range adjustment assembly. ;

[0012] S32, when At that time, determine the rotation gear. For high-end ;when At that time, determine the rotation gear. Mid-range ;when When this happens, the rotation gear is determined. Low-end ;

[0013] S4. Determine the range adjustment factor based on the rotary gear position. When rotating the gear For high-end hour, Values When rotating the gear Mid-range hour, Values When rotating the gear Low-end hour, Values ,in, ;

[0014] S5. Determine the adjustment step. The adjustment step is determined based on the single rotation angle of the range adjustment component. When rotating clockwise, each rotation Degrees, increment by 1 step; when rotating counterclockwise, each rotation Degree, step value decreases by 1;

[0015] S6. Calculate the current single-use range adjustment value. The calculation formula is as follows:

[0016]

[0017] S7. Calculate the cumulative adjustment value of the range. The calculation formula is as follows:

[0018]

[0019] in, Let be 1, ..., n, where n is the number of adjustments.

[0020] Preferably, the range adjustment component is a magnetic code ring, and the magnetic code ring is provided with The magnetic pole pair serves as a magnetic signal generating device, and the signal sensing component is a magnetic induction chip with two sensing terminals. The degree is .

[0021] Preferably, the base number is adjusted in step S1. The maximum volume range of the pipette is determined; the adjustment factor in step S4 is specifically determined as follows:

[0022] .

[0023] A second aspect of the present invention provides an adjustment system for the above-described pipette range adjustment method, comprising a control component, a range adjustment component, a rotation parameter determination component, and a range calculation component. The range adjustment component, rotation parameter determination component, and range calculation component are communicatively connected to the control component. The range adjustment component is used to adjust the pipette range during rotation. The rotation parameter determination component is used to determine the rotation direction, rotation interval, and single rotation angle of the range adjustment component and transmit these parameters to the control component. The control component determines the adjustment base. Determining the range adjustment factor based on the frequency of the rotation signal The adjustment direction is determined based on the rotation direction and the adjustment step is determined based on the single rotation angle. The range calculation component calculates and outputs the current single adjustment value and the cumulative adjustment value based on the above values.

[0024] Preferably, the control component is a main control board, and the range adjustment component is a magnetic code ring, on which a magnetic code ring is provided with Pole pairs, The degree is .

[0025] Preferably, the rotation parameter determining component is provided with a magnetic induction chip. The magnetic induction chip senses the signals of the magnetic pole pairs on the magnetic code ring to determine the rotation interval time and determines the rotation direction by the sequence of signals sensed at both ends of the magnetic induction chip. The rotation interval time of the magnetic code ring is determined by the signal interval time between two adjacent sets of magnetic pole pairs.

[0026] A third aspect of the present invention provides an adjustment device for the above-described pipette range adjustment method, comprising a display screen, a main housing, a magnetic code ring, a manual rotating component, a magnetic induction device, and a main control board; the manual rotating component, the magnetic code ring, the magnetic induction device, and the damping device are all disposed on the upper surface of the main housing, and the display screen is disposed above the manual rotating component.

[0027] The magnetic code ring is located below the manual rotating component and can drive the magnetic code ring to rotate when the manual rotating component rotates; the magnetic induction device is located below the magnetic code ring and there is a certain distance between the two; the magnetic induction device includes a magnetic induction chip and a magnetic induction cable, and the magnetic induction cable is communicatively connected to the main control board.

[0028] The magnetic code ring is provided with A set of evenly distributed magnetic pole pairs, each pair consisting of one S pole and one N pole. Group of magnetic pole pairs corresponding A virtual scale, each scale spaced apart. Each virtual tick mark represents one step.

[0029] The magnetic induction chip includes a first sensing end and a second sensing end. When the magnetic code ring rotates, the magnetic pole pairs generate high and low levels respectively through the first and second sensing ends of the magnetic induction chip. The magnetic induction chip transmits the high and low level sensing signals from the first and second sensing ends to the main control board. At the same time, the main control board determines the rotation direction of the magnetic code ring and determines the rotation interval time T and the single rotation angle based on the sequential sensing signals from the first and second sensing ends.

[0030] The main control board has three rotary positions. The three rotary gears are for high gear and high gear respectively. Mid-range and low-end The main control board determines the rotation gear based on the frequency of the sensed signal. Based on adjusting the rotation gear Determine the adjustment factor ; Determining the adjustment direction based on rotation method When the magnetic code ring rotates clockwise, The value is +1, which is applied when the magnetic code ring rotates counterclockwise. The value is -1, and the adjustment step is determined based on the angle of a single rotation. ;

[0031] The main control board uses the adjustment base. Adjusting the multiplier Adjusting direction and adjusting the step The product of the values ​​determines the current single adjustment value, and the cumulative adjustment value is obtained by adding the multiple adjustment values ​​together.

[0032] Preferably, it further includes damping devices, of which four damping devices are evenly arranged on the circumference of the upper surface of the main housing; a blind hole for placing the upper half of the damping device is provided on each adjacent pair of magnetic poles, and the magnetic code rings are evenly arranged with a common There are 1 blind hole, and the interval between two adjacent blind holes is 1 / 3. The magnetic code ring rotates every time... There is one and only one damping device entering the blind hole.

[0033] Preferably, each damping device includes a ceramic microsphere and a spring. The first end of the spring is disposed on the upper surface of the main housing, and the second end of the spring is disposed on the ceramic microsphere. When one of the damping devices corresponds to the blind hole position, the top one-third of the ceramic microsphere can enter the blind hole.

[0034] Preferably, the first sensing end and the second sensing end of the magnetic induction chip are respectively connected to the main control board via their respective signal lines. When the main control board first receives the sensing signal from the first sensing end of the magnetic induction chip, it determines that the rotation is clockwise. When the main control board first receives the sensing signal from the second sensing end of the magnetic induction chip, it determines that the rotation is counterclockwise.

[0035] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0036] (1) The range adjustment method of the present invention is accurate and precise, and can achieve stepless adjustment. Based on different adjustment levels, it can quickly adjust to the target adjustment amount. The rotation level combined with the calculation method can achieve range adjustment accurate to more than 0.1 μl for each level, which greatly improves the range adjustment accuracy and adjustment speed of the pipette, and can achieve rapid adjustment of a large range with high precision.

[0037] (2) The adjustment device of the present invention is equipped with a magnetic code ring and a manual rotating part for use. It is simple to operate and can ensure the accuracy of operation. It is ergonomic, has a large adjustment range, high range adjustment efficiency and high adjustment accuracy.

[0038] (3) The manual rotating component of the present invention can provide a gear feel and is equipped with a damping device to achieve small motion resistance, produce a slight damping feel, make it easier to make precise rotation adjustment, avoid misoperation and enable one-handed operation.

[0039] (4) The magnetic code ring of the present invention is made of permanent magnet material, and its connection with the magnetic induction chip is non-contact, so there is almost no risk of functional failure, and it can be used for a long time, thus extending the service life of the pipette. In addition, the overall manual rotating part has a simple structure, which can realize low-cost mass production and is suitable for large-scale promotion and application. Attached Figure Description

[0040] Figure 1 This is a schematic diagram of the method flow of the present invention;

[0041] Figure 2 This is a system block diagram of the present invention;

[0042] Figure 3 This is a schematic diagram of the intelligent pipette range adjustment of the present invention;

[0043] Figure 4 This is a schematic diagram of the magnetic code sensing device of the present invention;

[0044] Figure 5 This is a schematic diagram of the blind hole of the present invention;

[0045] Figure 6 This is a schematic diagram of the virtual scale position of the present invention;

[0046] Figure 7 This is a schematic diagram showing the position of the ceramic microspheres in this invention;

[0047] Figure 8 This is a schematic diagram showing the positions of the blind hole and the virtual scale in this invention;

[0048] Figure 9 This is a schematic diagram of the waveform direction of the present invention;

[0049] Figure 10 This is a schematic diagram of the pipette data transmission of the present invention;

[0050] Figure 11 This is a schematic diagram of the magnetic induction chip of the present invention. Detailed Implementation

[0051] Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings.

[0052] First, this invention provides a range adjustment method, such as... Figure 1 As shown, it includes the following steps:

[0053] S1. Determine the adjustment base. Adjustment base This is the maximum volume of the current pipette, determined by the model of the pipette.

[0054] S2. Determine the adjustment direction The adjustment direction is determined based on the rotation direction of the range adjustment component. When the adjustment direction is clockwise, The value is +1, and when the adjustment direction is counterclockwise, The value is -1. The adjustment direction is determined by the rotation direction of the range adjustment component. When the range adjustment component rotates clockwise, the adjustment direction is clockwise; conversely, when the range adjustment component rotates counterclockwise, the adjustment direction is counterclockwise. Specifically, the method for determining the rotation direction of the range adjustment component is as follows: multiple magnetic signal generators are evenly arranged on the range adjustment component. These generate signals during rotation and are sensed by a signal sensing component. The rotation direction of the range adjustment component is determined based on the order of the signals sensed at both ends of the signal sensing component. In a specific embodiment, the range adjustment component is a magnetic code ring, and the magnetic code ring is provided with... The magnetic pole pair serves as a magnetic signal generating device, and the signal sensing component is a magnetic induction chip with two sensing terminals. The degree is When the first sensing terminal of the magnetic induction chip senses the signal first, it determines that the rotation direction of the magnetic code ring is clockwise; when the second sensing terminal of the magnetic induction chip senses the signal first, it determines that the rotation direction of the magnetic code ring is counterclockwise.

[0055] S3. Determine the rotation gear. Determine the rotation gear. , ,in For high-end, Mid-range Set to low speed. First, determine the rotation interval of the range adjustment component. ,when At that time, determine the rotation gear. For high-end ;when At that time, determine the rotation gear. Mid-range ;when When this happens, the rotation gear is determined. Low-end Rotation interval time It is inversely proportional to the frequency of the rotation signal. In practical applications, The value is typically 10 milliseconds. The value is typically 20 milliseconds. However, this value can also be determined based on the specific pipette used.

[0056] S4. Determine the range adjustment factor based on the rotary gear position. When rotating the gear For high-end hour, Values When rotating the gear Mid-range hour, Values When rotating the gear Low-end hour, Values ,in, The specific steps for adjusting the multiplier value in step S4 are as follows:

[0057] .

[0058] In practical applications, the value of 'a' is generally 0.1, the value of 'b' is generally 0.01, and the value of 'c' is generally 0.001. These values ​​can also be determined based on the specific pipette used.

[0059] S5. Determine the adjustment step. The adjustment step is determined based on the single rotation angle of the range adjustment component. When rotating clockwise, each rotation The step value increases by 1 for every degree of counter-clockwise rotation; when rotating counter-clockwise, each rotation... The increment is 1, and the step value is reduced by 1.

[0060] S6. Calculate the current single-use range adjustment value. The calculation formula is as follows:

[0061]

[0062] S7. Calculate the cumulative adjustment value of the range. The calculation formula is as follows:

[0063]

[0064] in, Let be 1, ..., n, where n is the number of adjustments.

[0065] In practical applications, when adjusting the range, different rotation speeds can be selected to correspond to different range multiples, enabling multiple cumulative adjustments, achieving rapid adjustment of a large range, and ensuring adjustment accuracy on the basis of rapid large range adjustment.

[0066] Secondly, the present invention also provides a range adjustment system for performing the above-mentioned range adjustment. Specifically, as shown in the figure... Figure 2As shown, it includes a control component 101, a range adjustment component 102, a rotation parameter determination component 103, and a range calculation component 104. The range adjustment component 102, rotation parameter determination component 103, and range calculation component 104 are all communicatively connected to the control component 101. The range adjustment component 102 is used to adjust the pipette range during rotation. The rotation parameter determination component 103 is used to determine the rotation direction and rotation interval of the range adjustment component and transmit them to the control component. The control component 101 determines the adjustment base. Determining the range adjustment factor based on the frequency of the rotation signal The adjustment direction is determined based on the rotation direction and the adjustment step is determined based on the single rotation angle. The range calculation component 104 calculates and outputs the current single adjustment value and the cumulative adjustment value based on the above values.

[0067] In practical applications, the control component 101 is the main control board, and the range adjustment component 102 is a magnetic code ring, on which are set... Pole pairs, The degree is .

[0068] The rotation parameter determination component 103 is equipped with a magnetic induction chip. The magnetic induction chip senses the signal of the magnetic pole pair on the magnetic code ring and determines the rotation interval of the magnetic code ring. The rotation direction is determined by the sequence of signals sensed at both ends of the magnetic induction chip. The rotation interval of the magnetic code ring is determined by the signal interval of two adjacent magnetic pole pairs.

[0069] Finally, the present invention also provides an adjustment device, namely a smart pipette, such as... Figures 3 to 8 As shown, it includes a display screen 1, a main housing 8 (only part of the housing is shown in the figure), a magnetic code ring 4, a manual rotating component 3, a magnetic induction device, a damping device, and a main control board; the manual rotating component 3, the magnetic code ring 4, the magnetic induction device, and the damping device are all disposed on the upper surface of the main housing, and the display screen 1 is disposed above the manual rotating component 3. The manual rotating component 3 rotates by means of a rotating central shaft 2 and is connected to the display screen 1.

[0070] The magnetic code ring 4 is positioned below the manually rotating component 3, and the rotation of the manually rotating component 3 drives the magnetic code ring 4 to rotate; the magnetic induction device is positioned below the magnetic code ring 4, and there is a certain distance between the two; the magnetic induction device includes a magnetic induction chip 9 and a magnetic induction cable 7, such as Figure 10 As shown, the magnetic induction cable 7 is connected to the main control board for communication. Four damping devices are provided, evenly distributed around the circumference of the upper surface of the main housing 8. Each damping device includes a ceramic microsphere 5 and a spring 6. The first end of the spring 6 is located on the upper surface of the main housing 8, and the second end of the spring 6 is attached to the ceramic microsphere 5. When the damping device corresponds to the blind hole position, the top third of the ceramic microsphere can enter the blind hole.

[0071] To provide damping during rotation of the magnetic code ring 4 for accurate range positioning, four holes are provided on the main housing. Miniature springs are installed within these holes, with ceramic beads mounted on their upper ends. The ceramic beads contact the magnetic code ring 4. Figure 5 As shown, the magnetic code ring 4 has 18 blind holes 11. Whenever the magnetic code ring 4 rotates, when the blind holes reach the top of the ceramic bead, the upper third of the ceramic bead will sink into the blind hole due to the elasticity provided by the spring below, which will generate resistance to the rotating magnetic code ring 4, thus producing a damping sensation.

[0072] like Figure 4 As shown, the magnetic code ring 4 has 36 evenly distributed magnetic pole pairs 10, each pair including one S pole and one N pole, as shown. Figure 6 and Figure 8 As shown, 36 magnetic pole pairs 10 form 72 virtual positions 12, corresponding to 72 virtual scales, each scale being 5° apart. Each virtual scale increment represents one step. A blind hole for placing the upper part of the damping device is provided on every two adjacent magnetic pole pairs. The magnetic code ring 4 has a total of 18 blind holes 11 evenly distributed, with an interval of 20° between adjacent blind holes. Since the 36 magnetic pole pairs 10, the 18 blind holes 11, and the 4 sets of ceramic microspheres are all evenly distributed, as... Figure 7 As shown, the four sets of ceramic microbeads are placed at position 13, which are also evenly distributed on the magnetic code ring. For every 5° rotation of the magnetic code ring 4, only one ceramic microbead enters the blind hole, so that the rotational damping is also evenly distributed, which conforms to the ergonomic design and makes the use smoother.

[0073] like Figure 11 As shown, the magnetic induction chip includes a first sensing terminal (terminal A in the figure) and a second sensing terminal (terminal B in the figure). The magnetic induction cable connects the main control board to achieve data communication. When the magnetic code ring 4 rotates, the magnetic pole pairs generate high and low levels respectively through the first and second sensing terminals of the magnetic induction chip. The magnetic induction chip transmits the high and low level sensing signals from the first and second sensing terminals to the main control board. The main control board generates operation commands based on the real-time sensing signal characteristics and adjusts the range based on the operation commands. At the same time, the main control board determines the rotation direction of the magnetic code ring 4 based on the sequence of sensing signals from the first and second sensing terminals. The first and second sensing terminals of the magnetic induction chip are respectively connected to the main control board through their respective signal lines. When the main control board receives the sensing signal from the first sensing terminal of the magnetic induction chip first, it determines that the rotation is clockwise; when the main control board receives the sensing signal from the second sensing terminal of the magnetic induction chip first, it determines that the rotation is counterclockwise.

[0074] The frequency of the induced signal is used for the rotation interval time. It is an inverse relationship. This represents the time interval between the two sets of magnetic pole pairs passing through the magnetic induction control chip. The main control board has three rotary positions. The three rotary gears are for high gear and high gear respectively. Mid-range and low-end Different gear settings correspond to different rotation speeds, i.e., different sensor signal frequencies. In practical applications, this is determined by the rotation interval time. Determine the rotation gear Since the two sets of magnetic pole pairs are 5 degrees apart, the angular velocity of the ring rotation is ω = 2πf / 72, or ω = π / 36T.

[0075] When the time interval between two adjacent magnetic pole pairs passing through the magnetic induction control chip is between 0 and 10 milliseconds, it is determined to be high-end. When the time interval between the magnetic pole pairs passing the magnetic induction control chip is between 10 and 20 milliseconds, it is determined to be of medium range. When the time interval between the magnetic pole pairs passing the magnetic induction control chip is greater than or equal to 20 milliseconds, it is determined to be a low gear. Based on rotary gear and maximum range Determine the adjustment factor When the rotation speed is at a high level At that time, the magnetic code ring 4 adjusts according to the base number. The range of increase or decrease by 0.1 times, It is 0.1; when the rotation speed is at the medium level. At that time, the magnetic code ring 4 is adjusted according to the base number. The 0.01-fold increase / decrease range, It is 0.01; when the rotation speed is at a low setting. At that time, the magnetic code ring 4 is adjusted according to the base number. The 0.001-fold increase / decrease range, It is 0.001.

[0076] Adjust direction That is, the magnetic code ring 4 can rotate in both clockwise and counterclockwise directions. When the magnetic code ring 4 rotates clockwise, The value is +1, which is applied when the magnetic code ring 4 rotates counterclockwise. The value is -1. Adjust the direction. It can be divided into clockwise rotation and counterclockwise rotation. For example... Figure 9As shown, when the magnetic code ring rotates, the built-in magnetic pole pairs pass sequentially through the two sensing terminals of the magnetic induction chip. Terminal A in the diagram corresponds to the first sensing terminal, and terminal B corresponds to the second sensing terminal. The first sensing terminal, terminal A, is connected to signal line ①, and the second sensing terminal, terminal B, is connected to signal line ②. Due to the different directions of rotation, the order in which the waveforms appear on information lines ① and ② are also different. When the waveform of signal line ① appears first, it is determined to be clockwise rotation; when the waveform of signal line ② appears first, it is determined to be counterclockwise rotation.

[0077] In practical applications, the adjustment base The maximum volume of the pipette is determined based on the pipette model.

[0078] In this embodiment, the magnetic code ring 4 is provided with a total of 36 magnetic pole pairs. Therefore, every time it rotates 5 degrees, a pair of magnetic poles will pass through the magnetic induction chip. At this time, the range step increases by +1 (clockwise) or -1 (counterclockwise).

[0079] When the range is adjusted to the maximum value, rotating the magnetic code ring 4 clockwise will cause the range value to increase again from 0; when the range is adjusted to the minimum value (0), rotating the magnetic code ring 4 counterclockwise will cause the range value to decrease again from the maximum value.

[0080] For example, for a pipette with a maximum volume (adjustment base) of 1000 μL, when the volume has already been adjusted to 1000 μL, if the magnetic ring 4 is rotated clockwise, the volume value will start increasing again from 0 towards 1000 μL; while when the volume value is 0, if the magnetic ring 4 is rotated counterclockwise, the volume value will start decreasing from 1000 μL towards 0.

[0081] The magnetic induction chip is connected to the main control board. The electromagnetic signals collected by the magnetic induction chip are converted into digital signals and transmitted to the main control board. The main control board has a built-in database containing data models, such as establishing adjustment bases based on the specifications and models of the pipettes produced. A database of volume ranges, such as 100ul, 200ul, 300ul, 1000ul, 1250ul, 5000ul, etc., and the adjustment base value of the pipette is determined based on the device serial number of the pipette.

[0082] For example, an adjustment factor can be established based on the numerical range of the magnetic code ring signal frequency. The database, for example, establishes multiples from 0.001 to 0.1 based on frequencies such as 0-5ms, 5-10ms, 10-20ms, 20ms-30ms, and 30ms-50ms.

[0083] The main control board calls the database based on the collected electromagnetic signals and determines the target adjustment value of the range according to the signal parameters. Figure 10A schematic diagram of the pipette data transmission of the present invention is shown. Specific Implementation

[0084] This embodiment provides a method for adjusting the volume range of a certain type of pipette, specifically including the following steps:

[0085] S1. Determine the adjustment base. The main control board determines the maximum pipette range, i.e., the adjustment base, based on the pipette model. Adjusting the base number This indicates the maximum volume of the pipette model. In this embodiment, the maximum volume (adjustment base) is 200 μL. In other embodiments, the adjustment base is determined according to the maximum volume of different pipettes. For example, for a pipette with a maximum volume of 1000 μL, the adjustment base is 1000 μL. For a pipette with a maximum volume of 12.5 μL, the adjustment base is 12.5 μL.

[0086] S2. Determine the adjustment direction The main control board determines the adjustment direction based on the sequential sensing signals from the first and second sensing terminals of the magnetic induction chip. The adjustment direction is the rotation direction of the magnetic code ring. When the magnetic code ring rotates clockwise, The value is +1, which is applied when the magnetic code ring rotates counterclockwise. The value is -1.

[0087] S3. Determine the rotation gear. When the time interval between two adjacent magnetic pole pairs passing through the magnetic induction control chip is between 0 and 10 milliseconds, it is determined to be high-end. When the time interval between the magnetic pole pairs passing the magnetic induction control chip is between 10 and 20 milliseconds, it is determined to be of medium range. When the time interval between the magnetic pole pairs passing the magnetic induction control chip is greater than or equal to 20 milliseconds, it is determined to be a low gear. .

[0088] S4. Determine the range adjustment factor based on the rotary gear position. When the rotation speed is at a high level hour, It is 0.1; when the rotation speed is at the medium level. hour, It is 0.01; when the rotation speed is at a low setting. hour, It is 0.001.

[0089] S5. Determine the adjustment step. Adjusting the step size The increment value is determined by the rotation angle of the magnetic code ring. For every 5 degrees the ring rotates, the increment value increases by 1. When rotating clockwise, it is +1, and when rotating counterclockwise, it is -1.

[0090] S6. Calculate the current single-use range adjustment value. The calculation formula is as follows:

[0091]

[0092]

[0093] In step S6, when the magnetic code ring rotates clockwise, The value is +1, which is applied when the magnetic code ring rotates counterclockwise. The value is -1, and the ring rotates 5 degrees. The value increases or decreases by 1; clockwise rotation results in +1, and counterclockwise rotation results in -1.

[0094] S7. Sum the multiple adjustment values ​​to calculate the cumulative adjustment value of the range.

[0095] For example, in this embodiment, when the maximum volume (adjustment base) of the pipette is 200 microliters, the last adjusted volume is 20 ml. When it is rotated 30 degrees clockwise at a speed of 12 milliseconds, the final volume value is f(x) = f(1) + f(2), f(1) = 20 ml, f(2) = 0.01 * 200 * (30 / 5) * (+1) = 12 ml. After readjustment, the volume value is 32 ml.

[0096] In summary, when the manual rotating part is rotated quickly ( Figure 3-5 When rotating the manual rotary component at a slow speed, it can achieve rapid adjustment of large unit ranges (e.g., adjustment in 100ul units); when rotating the manual rotary component at a slow speed ( Figure 3-5 When adjusting the range, precise range adjustment can be performed (e.g., in 1µl increments). The range can be quickly set by combining fast and slow rotation of the manual rotary component.

[0097] This invention enables rapid adjustment of the pipette, saving time and effort, and avoids accidental touches and other operational errors, thus improving the user experience. Furthermore, it facilitates comprehensive recording of the pipetting process, promotes the upgrading of pipettes from manual to electric, and from electric to intelligent operation, and enables process traceability and experimental data analysis, ultimately benefiting scientific exploration and discovery.

[0098] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "setting," "connection," "fixing," "screw connection," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0099] The embodiments described above are merely preferred embodiments of the present invention and are not intended to limit the scope of the present invention. Various modifications and improvements made by those skilled in the art to the technical solutions of the present invention without departing from the spirit of the present invention should fall within the protection scope defined by the claims of the present invention.

Claims

1. A method for adjusting the volume range of a pipette, characterized in that: Specifically, it includes the following sub-steps: S1. Determine the adjustment base. The adjustment base R is the maximum volume of the pipette, which is determined by the model of the pipette; S2. Determine the adjustment direction The adjustment direction is determined based on the rotation direction of the range adjustment component. When the adjustment direction is clockwise, The value is +1, and when the adjustment direction is counterclockwise, The value is -1; the specific method for determining the rotation direction of the range adjustment component is as follows: multiple magnetic signal generating devices are evenly arranged on the range adjustment component, which generate signals when rotating and are sensed by the signal sensing component. The rotation direction of the range adjustment component is determined according to the order of the signals sensed at both ends of the signal sensing component. S3. Determine the rotation gear. Determine the rotation gear. , ,in For high-end, Mid-range For lower-end models, the specific steps include the following: S31. Determine the rotation interval of the range adjustment component. The interval between signals generated by adjacent magnetic signal generators on the range adjustment assembly is the rotation interval of the range adjustment assembly. ; S32, when At that time, determine the rotation gear. For high-end ;when At that time, determine the rotation gear. Mid-range ;when When this happens, the rotation gear is determined. Low-end ; S4. Determine the range adjustment factor based on the rotary gear position. When rotating the gear For high-end hour, Values When rotating the gear Mid-range hour, Values When rotating the gear Low-end hour, Values ,in, ; S5. Determine the adjustment step. The adjustment step is determined based on the single rotation angle of the range adjustment component. When rotating clockwise, each rotation Degrees, increment by 1 step; when rotating counterclockwise, each rotation Degree, step value decreases by 1; S6. Calculate the current single-use range adjustment value. The calculation formula is as follows: ； S7. Calculate the cumulative adjustment value of the range. The calculation formula is as follows: ； in, Let be 1, ..., n, where n is the number of adjustments.

2. The pipette range adjustment method according to claim 1, characterized in that: The range adjustment component is a magnetic code ring, on which are provided... The magnetic pole pair serves as a magnetic signal generating device, and the signal sensing component is a magnetic induction chip with two sensing terminals. The degree is .

3. The pipette range adjustment method according to claim 1, characterized in that: Adjusting the base number in step S1 The maximum volume range of the pipette is determined; the adjustment factor in step S4 is specifically determined as follows: .

4. An adjustment system for the pipette range adjustment method according to claim 1, characterized in that: It includes a control component, a range adjustment component, a rotation parameter determination component, and a range calculation component. The range adjustment component, rotation parameter determination component, and range calculation component are all communicatively connected to the control component. The range adjustment component is used to adjust the pipette range during rotation. The rotation parameter determination component determines the rotation direction, rotation interval, and single rotation angle of the range adjustment component and transmits these parameters to the control component. The control component determines the adjustment base. Based on rotary gear Determine the range adjustment factor And determine the adjustment direction based on the rotation direction. And determining the adjustment step based on a single rotation angle The range calculation component calculates and outputs the current single range adjustment value and the cumulative range adjustment value based on the above values.

5. The regulating system according to claim 4, characterized in that: The control component is a main control board, and the range adjustment component is a magnetic code ring, on which are arranged... Pole pairs, The degree is .

6. The regulating system according to claim 5, characterized in that: The rotation parameter determination component is equipped with a magnetic induction chip. The magnetic induction chip senses the signals of the magnetic pole pairs on the magnetic code ring to determine the rotation interval time and determines the rotation direction by the sequence of signals sensed at both ends of the magnetic induction chip. The rotation interval time of the magnetic code ring is determined by the signal interval time between two adjacent sets of magnetic pole pairs.

7. An adjusting device for the pipette range adjusting method according to claim 2, characterized in that: It includes a display screen, a main housing, a magnetic code ring, a manual rotating component, a magnetic induction device, and a main control board; the manual rotating component, the magnetic code ring, the magnetic induction device, and the damping device are all disposed on the upper surface of the main housing, and the display screen is disposed above the manual rotating component; The magnetic code ring is located below the manual rotating component and can drive the magnetic code ring to rotate when the manual rotating component rotates; the magnetic induction device is located below the magnetic code ring and there is a certain distance between the two; the magnetic induction device includes a magnetic induction chip and a magnetic induction cable, and the magnetic induction cable is communicatively connected to the main control board. The magnetic code ring is provided with A set of evenly distributed magnetic pole pairs, each pair consisting of one S pole and one N pole. Group of magnetic pole pairs corresponding A virtual scale, each scale spaced apart. Each virtual scale increment represents one step. The magnetic induction chip includes a first sensing end and a second sensing end. When the magnetic code ring rotates, the magnetic pole pairs passing through the first sensing end and the second sensing end of the magnetic induction chip respectively form a high level and a low level. The magnetic induction chip transmits the high level and low level sensing signals of the first sensing end and the second sensing end to the main control board. At the same time, the main control board determines the rotation direction of the magnetic code ring and determines the rotation interval time T and the single rotation angle based on the sequential sensing signals of the first sensing end and the second sensing end. The main control board has three rotary positions. The three rotary gears are for high gear and high gear respectively. Mid-range and low-end The main control board determines the rotation gear based on the frequency of the sensed signal. Based on rotary gear Determine the adjustment factor ; Adjustment direction determined by rotation direction When the magnetic code ring rotates clockwise, The value is +1, which is applied when the magnetic code ring rotates counterclockwise. The value is -1, and the adjustment step is determined based on the angle of a single rotation. ; The main control board uses the adjustment base. Adjusting the multiplier Adjusting direction and adjusting the step The product of the values ​​determines the current single range adjustment value, and the cumulative range adjustment value is obtained by adding the multiple adjustment values ​​together.

8. The adjusting device according to claim 7, characterized in that: It also includes damping devices, of which four are evenly arranged on the circumference of the upper surface of the main housing; a blind hole for placing the upper part of the damping device is provided on each adjacent pair of magnetic poles, and the magnetic code rings are evenly arranged with a total of There are 1 blind hole, and the interval between two adjacent blind holes is 1 / 3. The magnetic code ring rotates every time... There is one and only one damping device entering the blind hole.

9. The adjusting device according to claim 8, characterized in that: Each damping device includes a ceramic microsphere and a spring. The first end of the spring is disposed on the upper surface of the main housing, and the second end of the spring is disposed on the ceramic microsphere. When one of the damping devices corresponds to the blind hole position, the top one-third of the ceramic microsphere can enter the blind hole.

10. The adjusting device according to claim 7, characterized in that: The first and second sensing ends of the magnetic induction chip are respectively connected to the main control board via their respective signal lines. When the main control board first receives the sensing signal from the first sensing end, it determines that the rotation is clockwise. When the main control board first receives the sensing signal from the second sensing end, it determines that the rotation is counterclockwise.

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