A traditional Chinese medicine composition for treating constipation and a preparation method thereof

Abstract

The application discloses a traditional Chinese medicine composition for treating constipation and a preparation method thereof, and relates to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition for treating constipation prepared by the application is composed of Fructus Mume, Crataegus Pinnatifida Bunge, Longan Arillus, Mulberry, Rosa Rugosa, Radix Glycyrrhizae and Jujube, has the effects of tonifying qi and nourishing blood and warming yang and unblocking bowels, and shows good therapeutic effect on constipation.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating constipation and a preparation method thereof. BACKGROUND

[0002] In recent years, with the continuous rise of social and economic level, the quality of life of people increases, and the social pressure increases, the incidence of functional dyspepsia, functional constipation, functional diarrhea and gastroesophageal reflux and other gastrointestinal diseases also increases year by year, which becomes a common human disease. Constipation as a common gastrointestinal disease, the main symptoms include decreased defecation frequency, defecation difficulty, dry stool, dry mouth, abdominal distension, pain, restlessness, insomnia and other symptoms. Long-term constipation not only easily leads to the difficulty of excreting metabolic waste from the body, absorption and metabolism disorders, excessive accumulation of fat in the lower body, causing obesity, but also easily causes toxic substances to be reabsorbed into the liver, increasing the burden of the liver and damaging the function of the liver.

[0003] Many classic works of ancient Chinese medicine have realized that qi deficiency and blood deficiency can cause constipation. When treating, the method of tonifying qi and blood is used, which believes that the dryness is caused by the damage of spleen and stomach qi, and the fire evil consumes the true yin in the kidney. The kidney governs five fluids, and the deficiency of body fluid leads to the dryness and constipation of the large intestine. Therefore, the treatment should be clearing heat and moistening the intestine, regulating qi and removing stagnation, tonifying qi and nourishing yin. SUMMARY

[0004] The purpose of the present application is to provide a traditional Chinese medicine composition for treating constipation and a preparation method thereof to solve the problems in the prior art.

[0005] In order to solve the above technical problems, the present application provides the following technical scheme:

[0006] A traditional Chinese medicine composition for treating constipation mainly comprises: plum, hawthorn, longan meat, mulberry, rose flower, licorice, jujube.

[0007] As an optimization, the traditional Chinese medicine composition for treating constipation mainly comprises: 18-22 parts of plum, 8-12 parts of hawthorn, 8-12 parts of longan meat, 18-22 parts of mulberry, 18-22 parts of rose flower, 5-7 parts of licorice, 2-4 parts of jujube, by mass fraction.

[0008] As an optimization, the use method of the traditional Chinese medicine composition for treating constipation is: after water boiling to get juice and sealing the bag for standby, heating to 30-40 DEG C, and drinking within 30-60 min after meal.

[0009] A preparation method of a traditional Chinese medicine composition for treating constipation comprises the following preparation steps:

[0010] (1) take 18-22g of Chinese plum, 8-12g of hawthorn, 8-12g of longan meat, 18-22g of mulberry, 18-22g of rose, 5-7g of licorice, 2-4g of jujube;

[0011] (2) mix all the traditional Chinese medicinal materials uniformly, add 1800-2000mL of water, soak for 15-25min, then boil for 10-20min at 90-100℃, continue to boil for 5-15min until the medicinal amount is 260-300mL, naturally cool to room temperature, filter out the residue with gauze, seal the soup medicine in a bag, and get the traditional Chinese medicine composition soup bag, one bag a day, one bag at a time.

[0012] Compared with the prior art, the beneficial effects achieved by the present application are:

[0013] The traditional Chinese medicine composition prepared by the present application uses mulberry as the monarch drug, nourishes yin and kidney, supplements blood and moistens dryness, and promotes gastrointestinal peristalsis. Chinese plum is sour and astringent, and is flat in nature, and is distributed in liver, spleen, lung and large intestine meridians, has the functions of astringing lung and intestines, producing saliva, and preventing mulberry from being too excessive. Rose is sweet and slightly bitter in taste, and is warm in nature, and is distributed in liver and spleen meridians, has the functions of promoting qi and activating blood, and analgesic, is clear but not turbid, and harmonious but not violent, softens liver and wakes up stomach, flows qi and activates blood, and relieves stagnation, and has no side effects of pungent, warm and dry, and the two are used as ministerial drugs. Hawthorn is sour and sweet in taste, and is slightly warm in nature, and is distributed in spleen, stomach and liver meridians, has the functions of digesting food, strengthening stomach, promoting qi and dispersing blood stasis, and stopping diarrhea and dysentery, longan meat is sweet in taste, and is warm in nature, and is distributed in heart and spleen meridians, has the functions of tonifying heart and spleen, nourishing blood and tranquilizing, and the two are used as auxiliary drugs. Jujube is sweet in taste, and is warm in nature, and is distributed in spleen and stomach meridians, has the functions of tonifying middle energizer, benefiting qi, nourishing blood and tranquilizing; licorice tonifies spleen and benefits qi, relieves pain, regulates drug properties, and the two are used as ministerial drugs. The above drugs jointly play the functions of warming yang, relieving constipation, promoting qi and activating blood, and producing saliva, and in the treatment process, eliminating evil does not harm the normal.

[0014] According to the modern pharmacological research, mulberry is rich in dietary fiber, malic acid, vitamins and various minerals, can increase intestinal peristalsis and promote constipation; Chinese plum contains rich malic acid, can guide the water in the body to the large intestine, produce mild stimulation to the large intestine and promote intestinal peristalsis, let the accumulated toxins and feces in the intestinal tract be discharged out of the body as soon as possible, thereby relieving constipation; rose is rich in vitamins, alkaloids, primary pigments and flavonoids, can promote gastrointestinal peristalsis and speed up defecation, thereby relieving constipation; licorice contains flavonoids, coumarin compounds, triterpene saponins and triterpene aglycone compounds, and licorice saponins can increase gastric juice secretion, promote digestion and absorption, and improve constipation. DETAILED DESCRIPTION

[0015] The technical solutions in the embodiments of the present application will be clearly and completely described below with the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments of the present application, all the other embodiments obtained by a person of ordinary skill in the art without creative effort belong to the scope of protection of the present application.

[0016] Evaluation criteria: normal defecation once or twice a day without discomfort, which is recovery from constipation; increased stool frequency, shortened interval time, and smoother defecation than before, which is relief of constipation; no obvious improvement, which is invalid.

[0017] Example 1

[0018] Patient gender: female; age: 26 years old; disease: constipation for two years, abdominal distension, dry and hard stool.

[0019] The prescription of the traditional Chinese medicine composition for treating constipation is: 18 g of Fructus Mume, 8 g of Hawthorn Fruit, 8 g of Longan Arillus, 18 g of Mulberry Fruit, 18 g of Rosa Rugosa, 5 g of Licorice, and 2 g of Jujube.

[0020] The decocting process of the traditional Chinese medicine composition for treating constipation is: all the traditional Chinese medicinal materials are mixed uniformly, 2000 mL of water is added, soaked for 20 min, then boiled at 95℃ for 15 min, and then boiled at 10℃ until the medicinal material amount is 280 mL, naturally cooled to room temperature, filtered with gauze to remove the dregs, and then the medicinal soup is sealed in a bag to obtain the traditional Chinese medicine composition soup bag, which is taken once a day, one bag at a time.

[0021] The reexamination result is: after the first medication, the patient has the urge to defecate within 30 min, and after continuous medication for seven days, the constipation is cured, which shows that the traditional Chinese medicine composition for treating constipation prepared by the present application has a good therapeutic effect on constipation.

[0022] Example 2

[0023] Patient gender: male; age: 28 years old; disease: constipation for two years, abdominal distension, dry and hard stool, and incomplete defecation.

[0024] The prescription of the traditional Chinese medicine composition for treating constipation is: 22 g of Fructus Mume, 12 g of Hawthorn Fruit, 12 g of Longan Arillus, 22 g of Mulberry Fruit, 22 g of Rosa Rugosa, 7 g of Licorice, and 4 g of Jujube.

[0025] The decocting process of the traditional Chinese medicine composition for treating constipation is the same as that in Example 1.

[0026] The reexamination result is: after the first medication, the patient feels mild stomachache after 10 min, and defecates after 30 min, and after continuous medication for seven days, the constipation is cured, which shows that the traditional Chinese medicine composition for treating constipation prepared by the present application has a good therapeutic effect on constipation.

[0027] Example 3

[0028] Patient gender: female; age: 30 years old; condition: constipation for two years, dry stool, difficult defecation, excessive force defecation.

[0029] The prescription of the traditional Chinese medicine composition for treating constipation is: 18g of Fructus Mume, 8g of Hawthorn Fruit, 8g of Longan Arillus, 18g of Mulberry Fruit, 18g of Rose Flower, 5g of Licorice, and 2g of Jujube.

[0030] The decocting process of the traditional Chinese medicine composition for treating constipation is the same as that in Example 1.

[0031] The recheck result is that the patient has the defecation intention after 1h of taking the medicine for the first time, and defecates after 4h, and the constipation is cured after continuous medication for seven days, which shows that the prepared traditional Chinese medicine composition for treating constipation has a good therapeutic effect on constipation.

[0032] Example 4

[0033] Patient gender: male; age: 41 years old; condition: constipation for 2 years, difficult defecation, lower abdominal distending sensation, defecation once every three days.

[0034] The prescription of the traditional Chinese medicine composition for treating constipation is: 22g of Fructus Mume, 12g of Hawthorn Fruit, 12g of Longan Arillus, 22g of Mulberry Fruit, 22g of Rose Flower, 7g of Licorice, and 4g of Jujube.

[0035] The decocting process of the traditional Chinese medicine composition for treating constipation is the same as that in Example 1.

[0036] The recheck result is that the patient has the defecation intention after 1h of taking the medicine for the first time, and defecates after 4h, and the constipation is cured after continuous medication for seven days, which shows that the prepared traditional Chinese medicine composition for treating constipation has a good therapeutic effect on constipation.

[0037] Example 5

[0038] Patient gender: female; age: 31 years old; condition: constipation for four years, difficult defecation, dry stool, long defecation time.

[0039] The prescription of the traditional Chinese medicine composition for treating constipation is: 20g of Fructus Mume, 10g of Hawthorn Fruit, 10g of Longan Arillus, 20g of Mulberry Fruit, 20g of Rose Flower, 6g of Licorice, and 3g of Jujube.

[0040] The decocting process of the traditional Chinese medicine composition for treating constipation is the same as that in Example 1.

[0041] The recheck result is that the patient has the defecation intention after 5h of taking the medicine for the first time, and defecates more, and the constipation is relieved after continuous medication for seven days, which shows that the prepared traditional Chinese medicine composition for treating constipation has a good therapeutic effect on constipation.

[0042] Example 6

[0043] Patient gender: male; age: 60 years old; illness: constipation for 3 years, defecation difficult, long time for defecation, slight abdominal pain.

[0044] The prescription of the traditional Chinese medicine composition for treating constipation is: 18g of Fructus Mume, 8g of Hawthorn Fruit, 8g of Longan Arillus, 18g of Mulberry Fruit, 18g of Rosa Rugosa Flower, 5g of Licorice, and 2g of Jujube.

[0045] The decocting process of the traditional Chinese medicine composition for treating constipation is the same as that in Example 1.

[0046] The reexamination result shows that the patient starts defecation after using the medicine continuously for two days, and the constipation is relieved after using the medicine continuously for seven days, which indicates that the prepared traditional Chinese medicine composition for treating constipation has a good therapeutic effect on constipation.

[0047] Example 7

[0048] Patient gender: female; age: 78 years old; illness: constipation for five years, defecation difficult, dry stool, abdominal pain, and defecation incomplete.

[0049] The prescription of the traditional Chinese medicine composition for treating constipation is: 18g of Fructus Mume, 8g of Hawthorn Fruit, 8g of Longan Arillus, 18g of Mulberry Fruit, 18g of Rosa Rugosa Flower, 5g of Licorice, and 2g of Jujube.

[0050] The decocting process of the traditional Chinese medicine composition for treating constipation is the same as that in Example 1.

[0051] The reexamination result shows that the patient has slight abdominal pain and defecation intention after using the medicine for 2h for the first time, and the constipation condition is relieved after using the medicine continuously for seven days, which indicates that the prepared traditional Chinese medicine composition for treating constipation has a good therapeutic effect on constipation.

[0052] Example 8

[0053] Patient gender: female; age: 79 years old; illness: constipation for three years, defecation difficult, abdominal distension, defecation once every three days, and auxiliary use of Kaiselu.

[0054] The prescription of the traditional Chinese medicine composition for treating constipation is: 18g of Fructus Mume, 8g of Hawthorn Fruit, 8g of Longan Arillus, 18g of Mulberry Fruit, 18g of Rosa Rugosa Flower, 5g of Licorice, and 2g of Jujube.

[0055] The decocting process of the traditional Chinese medicine composition for treating constipation is the same as that in Example 1.

[0056] The reexamination result shows that the patient has normal defecation and no discomfort in the afternoon of the second day after using the medicine continuously for two days, and the constipation condition is relieved after using the medicine continuously for seven days, which indicates that the prepared traditional Chinese medicine composition for treating constipation has a good therapeutic effect on constipation.

[0057] Effect example

[0058] The Chinese medicine composition for treating constipation and the preparation method thereof provided in the application have been applied in practice. Up to now, the application cases have reached 218 cases. Since the base is too large, the treatment cases of only some typical and characteristic patients are selected and described in the embodiments. The Chinese medicine composition for treating constipation provided in the application has been applied in practice. In the actual use process, the cure rate of constipation symptoms is 79.8%, the remission rate is 16%, and the inefficiency rate is 4.2%.

[0059] It will be obvious to a person skilled in the art that the application is not limited to the details of the foregoing exemplary embodiments, and the application can be implemented in other concrete forms without departing from the spirit or essential characteristics of the application. Therefore, the embodiments should be considered as exemplary and non-limiting, and the scope of the application is defined by the appended claims rather than the foregoing description, and all changes falling within the meaning and range of the equivalent elements of the claims are intended to be embraced in the application. Any mark in the claims should not be considered as limiting the involved claim.

Claims

1. A traditional Chinese medicine composition for treating constipation, characterized in that, The traditional Chinese medicine composition for treating constipation is prepared from 18-22 parts of Fructus Mume, 8-12 parts of Hawthorn Fruit, 8-12 parts of Longan Arillus, 18-22 parts of Mulberry Fruit, 18-22 parts of Rosa Rugosa Flower, 5-7 parts of Radix Glycyrrhizae and 2-4 parts of Jujube.

2. The traditional Chinese medicine composition for treating constipation according to claim 1, characterized in that, The method for using the traditional Chinese medicine composition for treating constipation is as follows: after the water decoction is prepared and sealed in a bag, the water decoction is heated to 30-40 DEG C, and is drunk within 30-60 minutes after a meal.

3. The traditional Chinese medicine composition for treating constipation according to claim 1, characterized in that, The method comprises the following steps: (1) 18-22 g of Fructus Mume, 8-12 g of Hawthorn Fruit, 8-12 g of Longan Arillus, 18-22 g of Mulberry Fruit, 18-22 g of Rosa Rugosa Flower, 5-7 g of Radix Glycyrrhizae and 2-4 g of Jujube are weighed; (2) all the traditional Chinese medicinal materials are mixed uniformly, 1800-2000 mL of water is added, and after being soaked for 15-25 minutes, the traditional Chinese medicinal materials are decocted at 90-100 DEG C for 10-20 minutes, and then are continuously decocted at 5-15 DEG C until the medicinal material amount is 260-300 mL; after being naturally cooled to room temperature, the medicinal residues are removed by filtering with gauze, the decoction is sealed in a bag, and the traditional Chinese medicine composition decoction bag is obtained; one bag is taken once a day.