A traditional Chinese medicine health-care patch with the effect of regulating qi and inducing defecation and a preparation method thereof
By preparing a health care patch containing Chinese medicinal herbs such as Codonopsis pilosula, the shortcomings of Western medicine and Chinese herbal decoctions have been overcome, achieving effective treatment for children with constipation, significantly increasing small intestinal propulsion rate and improving symptoms of abdominal distension and pain, with good compliance.
Patent Information
- Application Number
- CN202410083781.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-19
- Publication Date
- 2025-12-26
- Estimated Expiration
- 2044-01-19
AI Technical Summary
Existing Western medicines for treating constipation have problems such as long-term use being detrimental to the autonomous function of gastrointestinal motility, difficulty in administering Chinese herbal decoctions and poor compliance, and bitter taste in traditional Chinese herbal pastes, which also leads to poor compliance among children.
A traditional Chinese medicine ointment is prepared using Chinese medicinal herbs such as Codonopsis pilosula, Cyperus rotundus, Amomum villosum, clove, cinnamon, Angelica sinensis, Perilla frutescens, Pogostemon cablin, rhubarb, fennel, prepared licorice root, stir-fried germinated barley, costus root, Cynanchum paniculatum, aged vinegar, rice wine, and honey. This ointment is then made into a traditional Chinese medicine health patch with the function of regulating qi and promoting bowel movement. The patch is applied to the Shenque (CV8) and Yongquan (KI1) acupoints of the affected child for treatment.
It significantly increases the small intestinal propulsion rate in constipated mice. Human trials showed an overall effective rate of up to 93.9%. It also significantly improves abdominal distension and abdominal pain symptoms in children with functional constipation, with better effects than lactulose oral solution, and has no serious adverse reactions.
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Abstract
Description
TECHNICAL FIELD
[0001] The present application belongs to the technical field of medical health supplies, and particularly relates to a traditional Chinese medicine health patch with the effects of regulating qi and inducing defecation and a preparation method thereof. BACKGROUND
[0002] Constipation is a common disease in children, and is clinically characterized by reduced defecation frequency, reduced fecal volume, dry and hard stool, and difficult defecation. Constipation is mainly functional constipation in traditional Chinese medicine, which is more common in clinical practice and accounts for more than 90% of pediatric constipation. Traditional Chinese medicine believes that children are the bodies of immature yin and yang, and the viscera are weak. Yin and yang, qi and blood are relatively insufficient. The living conditions are improved, and children do not know how to regulate their diet. They easily eat fatty and sweet foods, cold foods, which can easily damage the spleen and stomach, leading to weak spleen and stomach, insufficient transportation, and constipation.
[0003] Western medicine treatment is mainly based on osmotic laxatives and drugs that promote gastrointestinal peristalsis, but long-term self-regulation of gastrointestinal movement is not conducive to the function, and is also easy to cause repeated constipation, and is easy to damage the spleen and stomach, qi and blood, and has certain adverse reactions. Many parents are also worried that long-term medication will have adverse effects on the child's body. Traditional Chinese medicine decoction is bitter, and children generally have difficulty taking medicine, and have poor compliance. SUMMARY
[0004] In view of the deficiencies of the prior art, the present application aims to provide a traditional Chinese medicine health patch with the effects of regulating qi and inducing defecation and a preparation method thereof.
[0005] The purpose of the present application is achieved by the following technical solutions:
[0006] In a first aspect, the present application provides a traditional Chinese medicine paste, comprising the following raw materials in parts by weight: 50-70 parts of radix codonopsis, 50-70 parts of cyperus rotundus, 20-40 parts of amomum villosum, 20-40 parts of syzygium aromaticum, 20-40 parts of cinnamomum cassia, 20-40 parts of angelica sinensis, 35-55 parts of perilla frutescens, 20-40 parts of pachystachys johnstonii, 10-20 parts of rhubarb, 10-20 parts of cuminum cyminum, 20-40 parts of licorice, 50-70 parts of roasted foxtail millet, 20-40 parts of saussurea involucrata, 35-55 parts of xanthium sibiricum, 10-20 parts of vinegar, 10-20 parts of yellow rice wine, 5-15 parts of lubricant, and 400-500 parts of honey.
[0007] Preferably, the following raw materials are included in parts by weight: 60 parts of radix codonopsis, 60 parts of cyperus rotundus, 30 parts of amomum villosum, 30 parts of syzygium aromaticum, 30 parts of cinnamomum cassia, 30 parts of angelica sinensis, 45 parts of perilla frutescens, 30 parts of pachystachys johnstonii, 15 parts of rhubarb, 15 parts of cuminum cyminum, 30 parts of licorice, 60 parts of roasted foxtail millet, 30 parts of saussurea involucrata, 45 parts of xanthium sibiricum, 15 parts of vinegar, 15 parts of yellow rice wine, 10 parts of lubricant, and 450 parts of honey.
[0008] Preferably, each raw material is included in the following weight parts: Dangshen 55 parts, Xiangfu 65 parts, Amomum villosum 25 parts, Syzygium aromaticum 25 parts, Cinnamomum cassia 35 parts, Angelica sinensis 35 parts, Perilla frutescens 50 parts, Pogostemonis 25 parts, Radix et Rhizoma Rhei 10 parts, Foeniculum vulgare 20 parts, Radix Glycyrrhizae 35 parts, Fried foxtail millet 55 parts, Saussurea lappa 25 parts, Cyperus rotundus 50 parts, vinegar 20 parts, yellow rice wine 20 parts, lubricant 10 parts, honey 440 parts.
[0009] Preferably, each raw material is included in the following weight parts: Dangshen 65 parts, Xiangfu 55 parts, Amomum villosum 35 parts, Syzygium aromaticum 35 parts, Cinnamomum cassia 25 parts, Angelica sinensis 25 parts, Perilla frutescens 40 parts, Pogostemonis 35 parts, Radix et Rhizoma Rhei 20 parts, Foeniculum vulgare 10 parts, Radix Glycyrrhizae 25 parts, Fried foxtail millet 65 parts, Saussurea lappa 35 parts, Cyperus rotundus 40 parts, vinegar 10 parts, yellow rice wine 10 parts, lubricant 10 parts, honey 460 parts.
[0010] Preferably, the lubricant is sesame oil.
[0011] In a second aspect, the present application provides a use of the aforementioned Chinese medicine paste in the preparation of a Chinese medicine health-care patch.
[0012] In a third aspect, the present application provides a Chinese medicine health-care patch with the effects of regulating qi and inducing defecation, comprising a plasterer containing medical pressure-sensitive adhesive and the aforementioned Chinese medicine paste.
[0013] In a fourth aspect, the present application provides a preparation method of a Chinese medicine health-care patch with the effects of regulating qi and inducing defecation, comprising the following steps:
[0014] A1, honey: heat the honey to boiling, keep it slightly boiling, remove the foam and floating wax, then refine for a certain time, and take out the refined honey and cool it down;
[0015] A2, crushing: crush Dangshen, Xiangfu, Amomum villosum, Syzygium aromaticum, Cinnamomum cassia, Angelica sinensis, Perilla frutescens, Pogostemonis, Radix et Rhizoma Rhei, Foeniculum vulgare, Radix Glycyrrhizae, Fried foxtail millet, Saussurea lappa, Cyperus rotundus, respectively, and sieve them;
[0016] A3, mixing and lumping: mix the crushed and sieved raw materials of each Chinese medicine according to the proportion, add vinegar and yellow rice wine while mixing, then add refined honey and continue mixing, to obtain a medicine mixture;
[0017] A4, shaping: cool the medicine mixture, make it into a strip with uniform thickness, then add lubricant and cut it, to press it into a cake-shaped Chinese medicine paste;
[0018] A5, assembling and packaging: assemble the cake-shaped Chinese medicine paste with the plasterer containing medical pressure-sensitive adhesive, and package, to obtain the Chinese medicine health-care patch.
[0019] Preferably, in step A2, the sieving is through a 100-mesh sieve.
[0020] Preferably, in step A3, the weight of the ointment for treating the disease is 1.5-2.5 g / pill.
[0021] Compared with the prior art, the present application has the following beneficial effects:
[0022] The present application uses Dangshen, Xiangfu, Sharen, Dingxiang, Rougui, Dangui, Zixie, Guanghuoxiang, Dahuang, Xiaohuixiang, Zhigancao, Chaoguye, Muxiang, Xuchangqing as the functional components to prepare the Chinese medicine ointment, and the Chinese medicine health-care patch with the effect of regulating qi and inducing defecation is prepared therefrom. The animal experiment verifies that the Chinese medicine health-care patch can significantly increase the small intestine propulsion rate of constipated mice, and can achieve the effect equivalent to that of Maheren Wan. The human efficacy experiment verifies that the Chinese medicine health-care patch has a significant effect on functional constipation (qi-secretion syndrome), and the total effective rate is as high as 93.9%, and the improvement of abdominal distension and abdominal pain symptoms of constipated children is particularly obvious, and the effect is better than that of lactulose oral solution, and the Chinese medicine health-care patch has a very good effect of regulating qi and inducing defecation. DETAILED DESCRIPTION
[0023] The present application will be described in detail below with specific examples. The following examples will help those skilled in the art to further understand the present application, but do not limit the present application in any form. It should be pointed out that, for those skilled in the art, without departing from the concept of the present application, a number of modifications and improvements can be made. These all belong to the protection scope of the present application.
[0024] The words "preferred", "preferably", "more preferably" and the like in the present application refer to the embodiments of the present application which can provide certain beneficial effects in certain cases. However, other embodiments can also be preferred in the same or other cases. In addition, the description of one or more preferred embodiments does not imply that other embodiments are not usable, nor is it intended to exclude other embodiments from the scope of the present application.
[0025] It should be understood that, except in any operating examples, or otherwise indicated, all numbers expressing amounts of components, as used in the specification and claims, are to be understood as being modified in all instances by the term "about". Accordingly, unless indicated to the contrary, the numerical parameters set forth in the following specification and attached claims are approximations that can vary depending upon the desired properties sought to be obtained by the present application. At least, no attempt is made to limit the application of the doctrine of equivalents to the scope of the claims herein by virtue of the numerical description of the exemplary parameters. Each numerical parameter should at least be construed in light of the number of reported significant digits and by applying ordinary rounding techniques.
[0026] Notwithstanding that the numerical ranges and parameters setting forth the broad scope of the application are approximations, the numerical values set forth in the specific examples are reported as precisely as possible. Any numerical value, however, inherently contains certain errors necessarily resulting from the standard deviation found in their respective testing measurements.
[0027] In the following examples, each raw material used is a commercially available raw material.
[0028] Example 1
[0029] The present example provides a physiotherapy health care patch for Shenjue acupoint, Yongquan acupoint and the like, having the effect of regulating qi and inducing defecation, comprising a plasterer containing medical pressure-sensitive adhesive and a traditional Chinese medicine paste. The traditional Chinese medicine paste comprises each raw material and weight fraction shown in Table 1 as follows.
[0030] The preparation method of the physiotherapy health care patch comprises the following steps:
[0031] A1, honey: after the impurities of honey are removed, the honey is placed in a honey refining tank, heated to a gentle boil (about 116-118℃), and kept at a gentle boil while removing foam and floating wax. Continue to refine under the condition of gentle boiling until the mixture is sticky when touched with fingers, but no long white silk appears when the fingers are separated. The relative density is 1.38-1.42. Then quickly remove the pot and transfer it to a special storage barrel for cooling.
[0032] A2, crushing: the fourteen kinds of traditional Chinese medicine decoction pieces of Dangshen, Xiangfu, Sharen, Duhing, Ruzheng, Dangui, Qishuye, Guanghuoxiang, Dahuang, Xiaohuixiang, Zhugancao, Chaoguoya, Muxiang and Xuchangqing are crushed separately with a traditional Chinese medicine crusher and passed through a 100 mesh sieve.
[0033] A3, mixing and lumping: the traditional Chinese medicine raw material powders obtained in step A2 are weighed according to the weight fractions shown in Table 1 and placed in a mixer. While mixing, add vinegar and yellow rice wine. Mix for 30 minutes. Then take out and place in a slot-type mixer. Add the appropriate amount of refined honey obtained in step A1 and mix for 15 minutes to obtain a medicine mixture.
[0034] A4, molding: cool the medicine mixture obtained in step A3, then add it to the feeding bin of a strip making machine to make uniform thickness strips. Then use sesame oil as a lubricant, cut it with a knife and press it with a mold to make 1.8-2.0g / piece of round cake-shaped traditional Chinese medicine paste.
[0035] A5, assembly and packaging: assemble the round cake-shaped traditional Chinese medicine paste obtained in A4 with the plasterer containing medical pressure-sensitive adhesive, and package it to obtain the physiotherapy health care patch.
[0036] Example 2
[0037] The embodiment provides a physiotherapy health care patch for Shenjue acupoint, Yungquan acupoint and the like, which has the function of regulating qi and inducing defecation, and comprises a plasterer containing medical pressure-sensitive adhesive and a traditional Chinese medicine paste. The traditional Chinese medicine paste comprises each raw material and weight fraction shown in Table 1.
[0038] The preparation method of the physiotherapy health care patch is the same as that in Embodiment 1.
[0039] Embodiment 3
[0040] The embodiment provides a physiotherapy health care patch for Shenjue acupoint, Yungquan acupoint and the like, which has the function of regulating qi and inducing defecation, and comprises a plasterer containing medical pressure-sensitive adhesive and a traditional Chinese medicine paste. The traditional Chinese medicine paste comprises each raw material and weight fraction shown in Table 1.
[0041] The preparation method of the physiotherapy health care patch is the same as that in Embodiment 1.
[0042] Table 1
[0043]
[0044]
[0045] Comparative Example 1
[0046] The comparative example provides a physiotherapy health care patch for Shenjue acupoint, Yungquan acupoint and the like, which has the function of regulating qi and inducing defecation, and comprises a plasterer containing medical pressure-sensitive adhesive and a traditional Chinese medicine paste. The traditional Chinese medicine paste comprises each raw material and weight fraction shown in Table 2.
[0047] The preparation method of the physiotherapy health care patch is the same as that in Embodiment 1.
[0048] Comparative Example 2
[0049] The comparative example provides a physiotherapy health care patch for Shenjue acupoint, Yungquan acupoint and the like, which has the function of regulating qi and inducing defecation, and comprises a plasterer containing medical pressure-sensitive adhesive and a traditional Chinese medicine paste. The traditional Chinese medicine paste comprises each raw material and weight fraction shown in Table 2.
[0050] The preparation method of the physiotherapy health care patch is the same as that in Embodiment 1.
[0051] Comparative Example 3
[0052] The comparative example provides a physiotherapy health care patch for Shenjue acupoint, Yungquan acupoint and the like, which has the function of regulating qi and inducing defecation, and comprises a plasterer containing medical pressure-sensitive adhesive and a traditional Chinese medicine paste. The traditional Chinese medicine paste comprises each raw material and weight fraction shown in Table 2.
[0053] The preparation method of the physiotherapy health care patch is the same as that in Embodiment 1.
[0054] Comparative Example 4
[0055] The present comparative example provides a physiotherapy health care patch for Shenjue and Yongquan acupoints, which has the effect of regulating qi and inducing defecation, comprising a plaster containing medical pressure-sensitive adhesive and a traditional Chinese medicine paste. The traditional Chinese medicine paste comprises each raw material and weight fraction shown in Table 2.
[0056] The preparation method of the physiotherapy health care patch is the same as that of Example 1.
[0057] Table 2
[0058] Chinese medicine materials Example 1 Example 2 Example 3 Example 4 Radix Codonopsis 65 65 65 75 Rhizoma Cyperi 55 55 55 45 Fructus Amomi Rotundus 35 35 35 35 Caryophylli Flos 35 35 35 35 Cortex Cinnamomi 25 25 25 25 Radix Angelicae Sinensis 25 25 25 25 Perilla Leaf 40 40 40 40 Herba Pogostemonis 35 35 35 35 Radix et Rhizoma Rhei 0 20 20 20 Fructus Foeniculi 10 10 10 10 Radix Glycyrrhizae Preparata 25 0 25 25 Semen Setariae Preparatum 65 65 65 65 Radix Aucklandiae 35 35 35 35 Radix Paeoniae Alba 40 40 0 40 Vinegar 10 10 10 10 Yellow Rice Wine 10 10 10 10 Sesame Oil 10 10 10 10 Honey 480 485 500 460
[0059] Efficacy verification test
[0060] Test Example 1:
[0061] (1) Test materials: traditional Chinese medicine health care patches prepared in Examples 1-3 and Comparative Examples 1-4 and Mahu pills (Hubei Nuodesheng Pharmaceutical Co., Ltd.).
[0062] (2) Test subjects: 100 healthy Kunming mice, half male and half female, were randomly divided into 10 groups according to body weight, i.e. normal control group, model group, positive group and each traditional Chinese medicine health care patch group, 10 mice in each group.
[0063] (3) Treatment method: The mice were treated with depilation, 8% sodium sulfide was applied to the abdomen of the mice, the depilation area was 3cm×3cm, 1min later, the skin was washed with distilled water, and the mice were normally fed for 24h. Before the experiment, the mice were fasted for 12h without water, except for the normal control group, the rest of the groups were modeled, each group was given compound diphenoxylate 5mg / kg by gavage, the normal group was given the same amount of normal saline. 30min later, each group was given ink by gavage and each group was given medicine, the normal control group and the model group were given normal saline 5g / kg by gavage, the positive group was given Mahu pill liquid 5g / kg by gavage, and each traditional Chinese medicine health care patch group was given the corresponding traditional Chinese medicine health care patch on the abdomen.
[0064] (4) Observation index: immediately after administration for 25min, the mice were sacrificed, the whole small intestine from the pylorus back to the ileocecal junction was taken out, the mesentery was cut off, the small intestine was gently stretched, and then it was laid on white paper, the ink push length was measured and recorded, and the ink push percentage was calculated.
[0065]
[0066] (5) Experimental results:
[0067] The total length of the mouse small intestine, the length of the ink pushed in the intestine and the push rate were statistically analyzed, and the results are shown in Table 3.
[0068] Table 3 Effect of traditional Chinese medicine health care patch on small intestine propulsion in mice
[0069]
[0070] Note: Compared with the model group, **P<0.01, *P<0.05
[0071] From the results of Table 3, it can be seen that the normal control group was compared with the model group, P<0.01, so the modeling was successful. The health care patch groups of Examples 1-3 and Comparative Examples 1-4 and the positive group were compared with the model group, and it was found that the health care patch groups of Comparative Examples 1-4 had no statistical significance compared with the model group, P>0.05; the health care patch groups of Examples 2 and 3 had statistical differences compared with the model group, P<0.05; the health care patch group of Example 1 and the positive group had significant differences compared with the model group, P<0.01. The results showed that the traditional Chinese medicine health care patches of Examples 1-3 could significantly increase the small intestine propulsion rate of compound diphenoxylate-induced constipation mice, and the effect of the health care patch group of Example 1 was comparable to that of the positive group of the liquid medicine of Mahuang Wan.
[0072] Test Example 2:
[0073] (1) Experimental drugs: the traditional Chinese medicine health care patches prepared in Example 1 and lactulose oral solution.
[0074] (2) Test subjects: 1-12 years old, functional constipation (air constipation), symptoms: difficult defecation, incomplete defecation, or difficult and uncomfortable, chest and hypochondrium fullness, abdominal pain, frequent foul odor, white fur, and pulse string disease closely related to mood.
[0075] (3) Test method: 66 subjects meeting the requirements were selected and divided into a control group and a treatment group according to a random number table method, 33 cases in each group. The treatment group was treated with the traditional Chinese medicine health care patches prepared in Example 1, which were pasted on the Shengjue and Yungquan acupoints after disinfection, 1 patch for each acupoint, 2-3 times a day, pay attention to warmth, and also pay attention to observation after pasting to ensure that the fixation is proper and prevent the drug from slipping off. The control group was treated with lactulose oral solution, 5-10 ml for 1-6 year-old subjects each time, 10-15 ml for 7 years old and above subjects each time, all once a day, taken at breakfast.
[0076] (4) Observation index: first defecation time (after treatment), symptom disappearance time (abdominal distension and abdominal pain), and weekly defecation frequency.
[0077] (5) Efficacy judgment standard: Referring to the "Guiding Principles for Clinical Research of New Drugs of Traditional Chinese Medicine" (1993) "Guiding Principles for Clinical Research of New Drugs of Traditional Chinese Medicine for Treating Constipation", judgment was made. Cure: normal defecation or recovery to the pre-disease level, and all other symptoms disappeared; marked effect: constipation improved significantly, interval time and stool quality close to normal; or defecation within 72 hours, and most other symptoms disappeared; effective: defecation interval shortened by 1 day, or stool quality improved, and other symptoms improved; ineffective: constipation and other symptoms did not improve.
[0078] (6) Test results:
[0079] The patients in the treatment group and the control group were compared before treatment, and there was no significant difference in age, disease duration, disease condition, abdominal distension and abdominal pain symptoms between the two groups. The results of the treatment group and the control group after treatment are shown in Table 4 and Table 5.
[0080] Table 4 Comparison of constipation improvement of two groups
[0081] Group Time of first defecation (h) Time of disappearance of symptoms (h) Weekly defecation frequency (times) Treatment group (n=33) 8.8±1.2 45.2±7.2 4.3±0.9 Control group (n=33) 9.6±2.1 63.2±8.3 3.6±0.8 P value <0.05 <0.001 <0.01
[0082] Table 5 Comparison of clinical efficacy of two groups
[0083]
[0084] From the results of Table 4 and Table 5, it can be seen that the traditional Chinese medicine health care patch prepared in Example 1 has a significant effect on functional constipation (qi constipation), and the total effective rate is as high as 93.9%, and the improvement of abdominal distension and abdominal pain symptoms in children with constipation is particularly obvious, and the effect is better than that of the control group of lactulose oral solution, and no serious adverse reaction events are found in the test.
[0085] Typical cases:
[0086] 1. Zhang, male, 2 years old, constipation for more than 1 year, the child gradually developed constipation after adding complementary foods 1 year ago, with anal fissure bleeding, abdominal distension, poor sleep, poor appetite, normal urination, and no organic lesions. The traditional Chinese medicine health care patch prepared in Example 1 was used, which was pasted on the disinfecting Shengque point and Yongquan point, 1 patch for each acupoint, 2 times a day. After 3 days of use, the abdominal distension symptoms disappeared, the stool gradually adjusted, the appetite improved, and after 7 days of continuous use, the food intake returned to normal, the sleep improved significantly, the defecation returned to normal, and the spirit was lively.
[0087] 2. Chen, male, 6 years old, constipation for 2 months, 4-5 days a line, often need to use "Kaiselu" to help defecate, abdominal distension and abdominal pain, good appetite, morning breath, red tongue, less fur, no organic lesions. The traditional Chinese medicine health care patch prepared in Example 2 was used, which was pasted on the disinfecting Shengque point and Yongquan point, 1 patch for each acupoint, 2 times a day. After 2 days of use, the stool was successfully defecated. After 7 days of continuous use, the abdominal distension symptoms disappeared, the morning breath decreased, and the food intake increased.
[0088] 3. Ye Mou, female, 5 years old, 2 months ago began to appear defecation difficulty, the first segment of the stool is dry, like sheep dung, the second segment is normal, 2 days even 4-5 days 1 times, defecation anus pain unbearable, occasionally anal fissure blood, occasionally use glycerine help defecation, accompanied by abdominal distension, poor appetite, night sleeplessness, tongue pale and thin white fur. Adopt the health care patch prepared by example 3, paste on the sterilized Shenjue point and Yongquan point, 1 patch for each acupoint, 2 times a day. After 2 days of use, the first segment of the stool becomes soft, the second segment becomes thin, and abdominal distension is reduced. After 7 days of continuous use, the stool becomes soft, 1 time a day, abdominal distension disappears, and food intake increases.
[0089] The present application has many specific application ways, and the above description is only the preferred embodiment of the present application. It should be pointed out that the above examples are only used to illustrate the present application, and are not used to limit the protection scope of the present application. For ordinary skilled in the art, some improvements can be made without departing from the principles of the present application, and these improvements should be considered as the protection scope of the present application.
Claims
1. A Chinese medicine ointment having the effect of improving symptoms of constipation and abdominal distension, abdominal pain, characterized in that, The weight parts of each raw material consist of: Dangshen 50-70 parts, Xiangfu 50-70 parts, Amomum villosum 20-40 parts, Clove 20-40 parts, Cinnamon 20-40 parts, Angelica sinensis 20-40 parts, Perilla frutescens 35-55 parts, Pogostemonis 20-40 parts, Rhubarb 10-20 parts, Fennel 10-20 parts, Fried Licorice 20-40 parts, Fried Millet Sprout 50-70 parts, Costus 20-40 parts, Longkui 35-55 parts, Vinegar 10-20 parts, Yellow Rice Wine 10-20 parts, Lubricant 5-15 parts, Honey 400-500 parts.
2. The traditional Chinese medicine ointment for improving symptoms of constipation and abdominal distension and abdominal pain according to claim 1, characterized in that, The weight parts of each raw material consist of: Dangshen 60 parts, Xiangfu 60 parts, Amomum villosum 30 parts, Clove 30 parts, Cinnamon 30 parts, Angelica sinensis 30 parts, Perilla frutescens 45 parts, Pogostemonis 30 parts, Rhubarb 15 parts, Fennel 15 parts, Fried Licorice 30 parts, Fried Millet Sprout 60 parts, Costus 30 parts, Longkui 45 parts, Vinegar 15 parts, Yellow Rice Wine 15 parts, Lubricant 10 parts, Honey 450 parts.
3. The traditional Chinese medicine ointment for improving symptoms of constipation and abdominal distension and abdominal pain according to claim 1, characterized in that, The weight parts of each raw material consist of: Dangshen 55 parts, Xiangfu 65 parts, Amomum villosum 25 parts, Clove 25 parts, Cinnamon 35 parts, Angelica sinensis 35 parts, Perilla frutescens 50 parts, Pogostemonis 25 parts, Rhubarb 10 parts, Fennel 20 parts, Fried Licorice 35 parts, Fried Millet Sprout 55 parts, Costus 25 parts, Longkui 50 parts, Vinegar 20 parts, Yellow Rice Wine 20 parts, Lubricant 10 parts, Honey 440 parts.
4. The traditional Chinese medicine ointment for improving symptoms of constipation and abdominal distension and abdominal pain according to claim 1, characterized in that, The weight parts of each raw material consist of: Dangshen 65 parts, Xiangfu 55 parts, Amomum villosum 35 parts, Clove 35 parts, Cinnamon 25 parts, Angelica sinensis 25 parts, Perilla frutescens 40 parts, Pogostemonis 35 parts, Rhubarb 20 parts, Fennel 10 parts, Fried Licorice 25 parts, Fried Millet Sprout 65 parts, Costus 35 parts, Longkui 40 parts, Vinegar 10 parts, Yellow Rice Wine 10 parts, Lubricant 10 parts, Honey 460 parts.
5. The traditional Chinese medicine ointment according to any one of claims 1-4, characterized in that, The lubricant is sesame oil.
6. Use of the traditional Chinese medicine ointment for improving symptoms of constipation and abdominal distension and abdominal pain according to any one of claims 1-5 in the preparation of a traditional Chinese medicine health care patch.
7. A traditional Chinese medicine health-care patch having the effect of improving symptoms of constipation and abdominal distension, abdominal pain, characterized in that, The traditional Chinese medicine ointment for improving symptoms of constipation and abdominal distension and abdominal pain according to any one of claims 1-5 is applied to a patch applicator comprising a medical pressure-sensitive adhesive.
8. The preparation method of the traditional Chinese medicine health-care patch for improving constipation and abdominal distension and abdominal pain according to claim 7, characterized in that, The steps include: A1, Honey: after heating the honey to boiling, keep it slightly boiling, remove the foam and floating wax, then refine for a certain time, and then take out the refined honey and cool it down; A2, crushing: crush each of Dangshen, Xiangfu, Amomum villosum, Clove, Cinnamon, Angelica sinensis, Perilla frutescens, Pogostemonis, Rhubarb, Fennel, Fried Licorice, Fried Millet Sprout, Costus, Longkui, separately and sieve them; A3, mixing and forming: mix each of the crushed and sieved traditional Chinese medicine raw materials according to the proportion, then add vinegar and yellow rice wine while mixing, then add refined honey and continue mixing, to obtain a medicine mixture; A4, forming: after cooling the medicine mixture, make it into a strip with uniform thickness, then add lubricant and cut it, and then press it into a cake-shaped traditional Chinese medicine ointment; A5, assembling and packaging: assemble the cake-shaped traditional Chinese medicine ointment with the patch applicator comprising a medical pressure-sensitive adhesive, and then package it, to obtain the product.
9. The preparation method of the traditional Chinese medicine health patch with the effect of improving constipation, abdominal distension, and abdominal pain according to claim 8, characterized in that, In step A2, the sieving is through a 100-mesh sieve.
10. The method for preparing the traditional Chinese medicine health patch with the effect of improving constipation, abdominal distension, and abdominal pain according to claim 8, characterized in that, In step A3, the weight of the traditional Chinese medicine ointment is 1.5-2.5 g / piece.
Citation Information
Patent Citations
External emplastrum for curing food retention in child stomach and the preparing method
CN101036718A
Composition for treating constipation and preparation method thereof
CN114306494A