A biological vaccine production fermentation device and process

Abstract

The present invention discloses a biological vaccine production and fermentation device, which specifically relates to the technical field of vaccine production equipment, including a tank body, a rotating shaft, a mounting portion, a rotating rod, a rotating column, a defoaming needle, and a translation unit. The translation unit is arranged in the tank body and is used to drive the rotating rod to slide horizontally on the mounting portion when the rotating shaft rotates. The rotation radius of the defoaming needle is half of the spacing between two adjacent rotating columns, so that the translation unit drives the rotating rod to move horizontally on the mounting portion, thereby enabling the defoaming area of ​​the defoaming needle to cover all parts of the liquid surface of the protein stock solution in the tank body, thereby reducing the defoaming blind area of ​​the defoaming needle; the driving structure drives the driving disk to rotate, so that the eccentric hole on the driving disk can generate an axial rotation around the rotating shaft, thereby enabling the rotating rod to rotate around the rotating shaft, and also generating horizontal movement, thereby enabling the defoaming blind area of ​​the defoaming needle to be smaller, the structure is simple, and no electrical control equipment is required, thereby reducing the manufacturing cost.

Description

Technical Field

[0001] The present invention relates to the technical field of vaccine production equipment, and more specifically, to a biological vaccine production fermentation device and process. Background Art

[0002] With the rapid development of science and technology, the proportion of animal vaccines produced by bacterial fermentation is increasing. Researching and utilizing the special metabolic pathways of bacteria and fermenting bacteria in bacterial fermentation tanks has become the main way to produce animal vaccines.

[0003] When bacteria are fermenting, foam is generated. The current defoaming methods include physical defoaming and defoaming agent defoaming. When defoaming with a defoaming agent, the defoaming agent needs to be added to the fermented protein stock solution, but the amount of defoaming agent added cannot be accurately controlled, resulting in residual defoaming agent in the vaccine protein stock solution, affecting the quality of the protein stock solution. Therefore, it is safer to use a physical defoaming method. For example, a bacterial fermentation tank for animal vaccine production disclosed in Chinese utility model patent publication number CN215050312U, in which a stirring rod with serrated teeth is rotated to defoam the foam on the surface of the protein stock solution. However, since there is a spacing between the serrated teeth, when the stirring rod rotates, the foam between two adjacent serrated teeth may not be able to contact the serrated teeth, thereby resulting in a defoaming blind area for generating foam. Summary of the invention

[0004] In order to overcome the above-mentioned defects of the prior art, the embodiments of the present invention provide a biological vaccine production fermentation device and process. The technical problem to be solved by the present invention is that when the fermentation tank in the prior art physically defoams the foam of the protein stock solution, a defoaming blind area is easily generated.

[0005] To achieve the above object, the present invention provides the following technical solution: a biological vaccine production and fermentation device, comprising a tank body of a fermentation tank, wherein the tank body is provided with a feeding port and a discharging port, and further comprising:

[0006] A rotating shaft, the rotating shaft is coaxially rotatably connected to the tank body, and one end of the rotating shaft that penetrates into the tank body is fixedly connected with a mounting portion;

[0007] A rotating rod, the rotating rod being horizontally slidably connected to the mounting portion;

[0008] A rotating column, wherein the rotating column is provided with a plurality of rotating columns and vertically connected to the bottom of the rotating rod at equal intervals along the length direction of the rotating rod, a plurality of defoaming needles are fixedly connected to the lower end of the rotating column, the length direction of the defoaming needles forms an angle with the axial direction of the rotating column, and the rotation radius of the defoaming needles on the rotating column is half of the distance between two adjacent rotating columns;

[0009] The translation unit is arranged in the tank body and is used to drive the rotating rod to slide horizontally on the mounting portion when the rotating shaft rotates.

[0010] Furthermore, a motor seat is connected to the top of the tank body, a stepper motor is mounted on the motor seat, and an output shaft of the stepper motor is drivingly connected to the rotating shaft.

[0011] Furthermore, the translation unit comprises:

[0012] A sliding part, which is inserted into a sliding hole provided on the mounting part and slides freely horizontally;

[0013] A connecting column, wherein two connecting columns are provided and are respectively vertically fixed to the two ends of the sliding portion in the length direction, and the upper surface of the rotating rod is fixed to the lower ends of the two connecting columns;

[0014] A driving plate, the driving plate is coaxially rotatably connected to the tank body through a mounting bracket, and the driving plate is provided with an eccentric hole for the sliding part to freely pass through, and rollers are rotatably connected to both ends of the sliding part in the length direction, and the two rollers roll and contact the hole wall of the eccentric hole;

[0015] A driving structure is used to drive the driving disk to rotate axially around the rotating shaft.

[0016] Furthermore, the longitudinal section of the sliding portion is rectangular.

[0017] Furthermore, the driving structure comprises:

[0018] A fixing ring, the fixing ring is coaxially fixed to the upper end surface of the driving disk, and an internal gear portion is provided at the upper end of the fixing ring;

[0019] A driving gear, the driving gear is sleeved on the rotating shaft, and the driving gear is located inside the ring hole of the fixing ring;

[0020] A mounting ring, the mounting ring is coaxially fixed to the inner wall of the tank body and is located above the driving gear, and a connecting plate is fixed to the inner wall of the mounting ring;

[0021] The intermediate gears are provided with two intermediate gears and are rotatably connected to the connecting plate. The intermediate gears are meshed with the internal gear part and the driving gear.

[0022] Furthermore, the two intermediate gears are symmetrically arranged along the axial direction of the rotating shaft.

[0023] Furthermore, the rotating column is rotatably connected to the rotating rod, and a rotating unit is provided on the rotating rod. The rotating unit is used to drive the plurality of rotating columns to rotate when the rotating rod moves horizontally, and the rotation directions of two adjacent rotating columns are opposite.

[0024] Furthermore, the rotating unit comprises:

[0025] A sliding rod, the sliding rod is inserted into the sliding groove provided by the rotating rod and slides freely in the sliding groove, a mounting cavity in the form of a notch is provided on a downward side of the sliding rod, and the upper end of the rotating column penetrates into the mounting cavity and is provided with a gear portion;

[0026] A strip plate, wherein two strip plates are provided and are respectively fixed to the inner walls of opposite sides of the installation cavity, and a plurality of rack parts are provided at equal intervals on a side of the strip plate facing the gear part, and the rack parts on the two strip plates are staggered so that the gear parts on the two adjacent rotating columns are respectively meshed with the rack parts on the two strip plates, so that when the sliding rod slides in the sliding groove, the two adjacent rotating columns rotate synchronously in opposite directions;

[0027] A connecting structure is used to connect the sliding rod and the mounting portion.

[0028] Furthermore, the connection structure includes a connection pin vertically fixed to the top of the sliding rod, the connection pin passes through the rotating rod and is arranged at the bottom of the mounting portion, and a waist-shaped hole is opened on the upper surface of the rotating rod for the connection pin to pass freely.

[0029] A biological vaccine production fermentation process, using the above-mentioned biological vaccine production fermentation device, comprises:

[0030] The protein stock solution is added into the tank from the feeding port, and the temperature inside the tank is adjusted to allow the protein stock solution to ferment;

[0031] During the fermentation process of the protein stock solution used in the vaccine, foam is generated on the surface of the protein stock solution. At this time, the rotating shaft rotates to drive the mounting part to rotate, so that the rotating rod rotates synchronously around the axial direction of the rotating shaft. During the rotation process, multiple defoamers on the rotating column perform defoaming treatment on the foam on the surface of the protein stock solution.

[0032] During the rotation of the rotating shaft, the translation unit drives the rotating rod to move horizontally relative to the mounting portion, so that the rotating column drives the defoaming needle to move horizontally, thereby reducing the defoaming blind area of ​​the foam on the surface of the protein stock solution.

[0033] Technical effects and advantages of the present invention:

[0034] By arranging a defoaming needle, a rotating rod and a translation unit, and the rotation radius of the defoaming needle is half of the distance between two adjacent rotating columns, the translation unit drives the rotating rod to move horizontally on the mounting portion, so that the defoaming area of ​​the defoaming needle can cover all parts of the liquid surface of the protein stock solution in the tank, thereby reducing the defoaming blind area of ​​the defoaming needle;

[0035] When the rotating shaft rotates, the driving structure drives the driving disc to rotate, so that the eccentric hole on the driving disc can rotate around the axial direction of the rotating shaft, thereby enabling the rotating rod to rotate around the rotating shaft and also to generate horizontal movement, thereby making the defoaming blind area of ​​the defoaming needle smaller, the structure is simple, and no electrical control equipment is required, thereby reducing the manufacturing cost;

[0036] By arranging the sliding rod, the strip plate, the rack part and the gear part, when the rotating rod moves horizontally relative to the mounting part, the strip plate will move relative to the rotating rod, so that the rack part can mesh with the gear part for transmission. During meshing transmission, the gear part on the rotating column will be driven to rotate. During rotation, the defoaming needle can rotate around the axial direction of the rotating column, so that the defoaming needle can rotate, thereby further increasing the defoaming area of ​​a single defoaming needle and improving the defoaming efficiency.

[0037] By setting two strip plates and staggeredly setting the rack parts on the two strip plates, the two adjacent rotating columns can rotate synchronously in opposite directions, so that the defoaming needles on the two adjacent rotating columns turn in opposite directions, avoiding the defoaming needles turning in the same direction, causing the liquid surface of the protein stock solution to flow in a fixed direction, so that when defoaming is performed, the foam flows with the liquid surface and moves away from the defoaming needle, affecting the defoaming efficiency of the foam. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] Figure 1 It is a partial structural cross-sectional schematic diagram of a biological vaccine production and fermentation device in the present invention;

[0039] Figure 2 for Figure 1 The schematic diagram of the structure after the tank is omitted;

[0040] Figure 3 for Figure 2 Schematic diagram of the explosion decomposition of the structure;

[0041] Figure 4 for Figure 2 Schematic diagram of the structure from an upward angle;

[0042] Figure 5 for Figure 4 A magnified schematic diagram of the local structure at point A;

[0043] Figure 6 It is a schematic diagram of the structure after the rotating rod, the sliding part and the multiple rotating columns are assembled in the present invention;

[0044] Figure 7 It is a schematic diagram of the structure after the sliding rod and the strip plate are assembled in the present invention;

[0045] Figure 8 It is a schematic diagram of the structure of the drive disk in the present invention.

[0046] The accompanying drawings are marked as follows: 1. stepper motor; 2. tank body; 3. rotating shaft; 4. internal gear part; 5. intermediate gear; 6. fixed ring; 7. rotating rod; 8. defoaming needle; 9. feeding port; 10. mounting ring; 11. connecting plate; 12. driving gear; 13. driving disk; 14. sliding rod; 15. rotating column; 16. discharge port; 17. sleeve ring; 18. eccentric hole; 19. strip plate; 20. gear part; 21. rack part; 22. mounting part; 23. sliding part; 24. waist-shaped hole; 25. connecting column; 26. roller; 27. mounting cavity; 28. connecting pin. DETAILED DESCRIPTION

[0047] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0048] like Figure 1-Figure 8As shown, the present embodiment discloses: a biological vaccine production and fermentation device, including a tank body 2 of a fermentation tank, a feeding port 9 and a discharging port 16 are provided on the tank body 2, a certain amount of protein stock solution is fed into the tank body 2 from the feeding port 9, and the inside of the tank body 2 is heated, the discharging port 16 and the feeding port 9 are both provided with a conveying device, and the discharging port 16 and the feeding port 9 are each installed with a control valve, the top of the tank body 2 is screwed to a motor seat, a rotating shaft 3 is coaxially connected to the motor seat through a mounting bearing, the lower end of the rotating shaft 3 penetrates into the tank body 2, and a mounting portion 22 is welded thereto, in addition, a stepping motor 1 is installed on the motor seat, the output shaft of the stepping motor 1 is drivingly connected to the rotating shaft 3, and a sliding portion 23 is horizontally penetrated on the mounting portion 22, that is, a horizontal and longitudinal sliding portion 23 is provided on the mounting portion 22. The sliding hole is rectangular in cross section, and the sliding part 23 and the sliding hole form a sliding fit. In addition, the length direction of the sliding part 23 is consistent with the sliding direction of the sliding part 23 in the sliding hole. The two ends of the sliding part 23 in the length direction are respectively welded with a connecting column 25 extending downward, and the lower ends of the two connecting columns 25 are jointly and horizontally welded with a rotating rod 7, and the rotating rod 7 can rotate around the axial direction of the rotating shaft 3. In addition, the bottom of the rotating rod 7 is vertically rotatably connected with a plurality of rotating columns 15 at equal intervals along the length direction of the rotating rod 7, and the lower end of the rotating column 15 is welded with a plurality of defoaming needles 8. The length direction of the defoaming needle 8 forms an angle with the axial direction of the rotating column 15. The rotation radius size of the defoaming needle 8 on the rotating column 15 is half of the spacing size between two adjacent rotating columns 15, and the horizontal plane where the lower end of the defoaming needle 8 is located is flush with the liquid surface of the protein stock solution;

[0049] When defoaming the foam on the surface of the protein stock solution, firstly, the external power supply is turned on and the stepper motor 1 is started. The output shaft of the stepper motor 1 rotates and drives the rotating shaft 3 to rotate. When the rotating shaft 3 rotates, it drives the mounting portion 22 to rotate, thereby causing the rotating rod 7 to rotate around the axial direction of the rotating shaft 3. During the rotation process, the defoaming needle 8 can cut the foam on the surface of the protein stock solution, thereby achieving defoaming treatment.

[0050] A bracket (not shown in the figure) is welded to the inner wall of the tank body 2, and a driving disk 13 is rotatably connected to the bracket by installing a bearing. The driving disk 13 is coaxial with the tank body 2, and the driving disk 13 is provided with an eccentric hole 18 for the sliding portion 23 to pass freely. The sliding portion 23 is rotatably connected to rollers 26 at both ends in the length direction. The two rollers 26 roll in contact with the hole wall of the eccentric hole 18. A fixing ring 6 is coaxially welded to the upper end surface of the driving disk 13, and an inner gear portion 4 is provided on the inner side wall of the upper end of the fixing ring 6. A collar 17 is fixedly sleeved on the rotating shaft 3, and a plurality of connecting rods are welded to the collar 17. , and a driving gear 12 is welded together at one end of the connecting rod away from the collar 17, and the driving gear 12 is located inside the ring hole of the fixing ring 6, a mounting ring 10 is coaxially welded to the inner wall of the tank body 2, and the mounting ring 10 is located above the driving gear 12, a connecting plate 11 is fixedly connected to the inner wall of the mounting ring 10, and an avoidance hole for the rotating shaft 3 to pass freely is opened on the connecting plate 11, and two intermediate gears 5 are rotatably connected to the connecting plate 11 through a mounting pivot, and the intermediate gear 5 is meshed with the internal gear part 4 and the driving gear 12, and the other two intermediate gears 5 are symmetrically arranged along the axial direction of the rotating shaft 3;

[0051] When the rotating shaft 3 rotates, it will drive the driving gear 12 to rotate. When the driving gear 12 rotates, the meshing transmission between the driving gear 12 and the intermediate gear 5 makes the intermediate gear 5 rotate synchronously. In addition, the intermediate gear 5 meshes with the internal gear part 4, so that the driving gear 12 can drive the internal gear part 4 to mesh and rotate, so that the driving disk 13 rotates around the axial direction of the rotating shaft 3, so that the eccentric hole 18 on the driving disk 13 will rotate around the axial direction of the rotating shaft 3. In addition, the rotation direction of the driving disk 13 is opposite to that of the rotating shaft 3, so that the roller 26 rolls on the hole wall of the eccentric hole 18. Since the rotation direction of the driving disk 13 is opposite to that of the rotating shaft 3, the position of the roller 26 on the hole wall of the eccentric hole 18 changes, so the sliding part 23 is driven to move horizontally, so as to achieve the purpose of driving the rotating rod 7 to move horizontally.

[0052] The rotating rod 7 is provided with a sliding groove in the form of a through hole along its length direction, and a sliding rod 14 is installed in the sliding groove in a telescopic manner. The sliding rod 14 can slide freely along the length direction of the rotating rod 7 in the sliding groove. A mounting cavity 27 in the form of a notch is provided on the downward side of the sliding rod 14. The upper end of the rotating column 15 penetrates into the mounting cavity 27 and is provided with a gear portion 20. A strip plate 19 is welded on the inner walls on opposite sides of the mounting cavity 27. The length direction of the strip plate 19 is parallel to the length direction of the rotating rod 7, and the strip plate 19 faces the gear portion 20. A plurality of rack parts 21 are provided at equal intervals on one side, and the rack parts 21 on the two strip plates 19 are staggered so that the gear parts 20 on the two adjacent rotating columns 15 are respectively meshed with the rack parts 21 on the two strip plates 19, so that when the sliding rod 14 slides in the sliding groove, the two adjacent rotating columns 15 rotate synchronously in opposite directions. A connecting pin 28 is vertically welded to the top of the sliding rod 14, and the connecting pin 28 passes through the rotating rod 7 and is arranged at the bottom of the mounting part 22. A waist-shaped hole 24 is opened on the upper surface of the rotating rod 7 for the connecting pin 28 to pass freely.

[0053] When the rotating rod 7 moves horizontally, since the connecting pin 28, the sliding rod 14, and the strip plate 19 are stationary relative to the mounting portion 22, when the rotating rod 7 moves horizontally, the gear portion 20 on the rotating column 15 and the rack portions 21 on the two strip plates 19 are meshed and transmitted accordingly. Since the rack portions 21 on the two strip plates 19 are staggered, the rotation directions of the two adjacent rotating columns 15 are opposite. At the same time, the connecting pin 28 will move in the waist-shaped hole 24.

[0054] The working principle of the present invention is as follows: a certain amount of protein stock solution is added into the tank body 2 from the feeding port 9, and the inside of the tank body 2 is heated, and the protein stock solution is fermented by the fermentation process in the prior art. During the fermentation process, foam is generated on the liquid surface of the protein stock solution. At this time, the external power supply is firstly connected and the stepper motor 1 is started, and the output shaft of the stepper motor 1 rotates, and drives the rotating shaft 3 to rotate. When the rotating shaft 3 rotates, it will drive the mounting part 22 to rotate, and then the rotating rod 7 rotates around the axial direction of the rotating shaft 3;

[0055] When the rotating shaft 3 rotates, it will drive the driving gear 12 to rotate. When the driving gear 12 rotates, the meshing transmission between the driving gear 12 and the intermediate gear 5 makes the intermediate gear 5 rotate synchronously. In addition, the intermediate gear 5 meshes with the internal gear part 4, so that the driving gear 12 can drive the internal gear part 4 to mesh and rotate, so that the driving disk 13 rotates around the axial direction of the rotating shaft 3, so that the eccentric hole 18 on the driving disk 13 will rotate around the axial direction of the rotating shaft 3. In addition, the rotation direction of the driving disk 13 is opposite to that of the rotating shaft 3, so that the roller 26 rolls on the hole wall of the eccentric hole 18. Since the rotation direction of the driving disk 13 is opposite to that of the rotating shaft 3, the position of the roller 26 on the hole wall of the eccentric hole 18 changes, so the sliding part 23 is driven to move horizontally, so as to achieve the purpose of driving the rotating rod 7 to move horizontally, so that the defoaming needle 8 can perform defoaming treatment in a larger area.

[0056] When the rotating rod 7 moves horizontally, since the connecting pin 28, the sliding rod 14, and the strip plate 19 are stationary relative to the mounting portion 22, the gear portion 20 on the rotating column 15 and the rack portions 21 on the two strip plates 19 are meshed and transmitted accordingly. Since the rack portions 21 on the two strip plates 19 are staggered, the rotation directions of the two adjacent rotating columns 15 are opposite, so that the defoaming needles 8 on the two adjacent rotating columns 15 turn in opposite directions, avoiding the defoaming needles 8 turning in the same direction, causing the liquid surface of the protein stock solution to flow in a fixed direction, so that when defoaming is performed, the foam flows with the liquid surface and moves away from the defoaming needle 8, affecting the defoaming efficiency of the foam.

[0057] Finally, a few points should be explained: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, which may refer to mechanical connection or electrical connection, or internal communication between two components, or direct connection. "upper", "lower", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship may change;

[0058] Secondly: In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other;

[0059] Finally: The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A biological vaccine production fermentation device, comprising a tank body (2) of a fermentation tank, wherein the tank body (2) is provided with a feeding port (9) and a discharging port (16), characterized in that: Also includes: A rotating shaft (3), the rotating shaft (3) being coaxially rotatably connected to the tank body (2), and one end of the rotating shaft (3) penetrating into the tank body (2) being fixedly connected to a mounting portion (22); A rotating rod (7), the rotating rod (7) being horizontally slidably connected to the mounting portion (22); A rotating column (15), wherein a plurality of the rotating columns (15) are provided and are vertically connected to the bottom of the rotating rod (7) at equal intervals along the length direction of the rotating rod (7); a plurality of defoaming needles (8) are fixedly connected to the lower end of the rotating column (15); the length direction of the defoaming needles (8) forms an angle with the axial direction of the rotating column (15); and the rotation radius of the defoaming needles (8) on the rotating column (15) is half the spacing between two adjacent rotating columns (15); A translation unit, the translation unit being arranged in the tank body (2) and being used for driving the rotating rod (7) to slide horizontally on the mounting portion (22) when the rotating shaft (3) rotates; the translation unit comprising: A sliding portion (23), the sliding portion (23) being inserted into a sliding hole provided on the mounting portion (22) and being freely slidable horizontally; Connecting columns (25), two of which are provided and are respectively vertically fixed to the two ends of the sliding portion (23) in the length direction, and the upper surface of the rotating rod (7) is fixed to the lower ends of the two connecting columns (25); a driving disk (13), the driving disk (13) being coaxially rotatably connected to the tank body (2) via a mounting bracket, the driving disk (13) being provided with an eccentric hole (18) for the sliding portion (23) to freely pass through, the sliding portion (23) being rotatably connected to rollers (26) at both ends in the length direction, the two rollers (26) rollingly contacting the hole wall of the eccentric hole (18); A driving structure, the driving structure being used to drive the driving disk (13) to rotate axially around the rotating shaft (3); The driving structure comprises: A fixing ring (6), the fixing ring (6) being coaxially fixed to the upper end surface of the driving disk (13), and an internal gear portion (4) being provided at the upper end portion of the fixing ring (6); A driving gear (12), the driving gear (12) being sleeved on the rotating shaft (3), and the driving gear (12) being located inside the ring hole of the fixing ring (6); A mounting ring (10), the mounting ring (10) being coaxially fixed to the inner wall of the tank body (2) and located above the driving gear (12), and a connecting plate (11) being fixed to the inner wall of the mounting ring (10); Intermediate gears (5), two intermediate gears (5) are provided and are rotatably connected to the connecting plate (11), and the intermediate gears (5) are meshed with the internal gear portion (4) and the driving gear (12); The rotating column (15) is rotatably connected to the rotating rod (7), and a rotating unit is provided on the rotating rod (7). The rotating unit is used to drive the plurality of rotating columns (15) to rotate when the rotating rod (7) moves horizontally, and the rotation directions of two adjacent rotating columns (15) are opposite; The rotating unit comprises: A sliding rod (14), the sliding rod (14) being inserted into a sliding groove provided in the rotating rod (7) and being able to slide freely in the sliding groove, a mounting cavity (27) in the form of a notch being provided on a downward side of the sliding rod (14), the upper end of the rotating column (15) being inserted into the mounting cavity (27) and being provided with a gear portion (20); a strip plate (19), wherein two strip plates (19) are provided and are respectively fixed to the inner walls of opposite sides of the mounting cavity (27); a plurality of rack portions (21) are provided at equal intervals on a side of the strip plate (19) facing the gear portion (20); the rack portions (21) on the two strip plates (19) are arranged alternately, so that the gear portions (20) on the two adjacent rotating columns (15) are respectively meshed with the rack portions (21) on the two strip plates (19), so that when the sliding rod (14) slides in the sliding groove, the two adjacent rotating columns (15) rotate synchronously in opposite directions; A connecting structure, wherein the connecting structure is used to connect the sliding rod (14) and the mounting portion (22).

2. The biological vaccine production and fermentation device according to claim 1, characterized in that: The top of the tank body (2) is connected to a motor seat, a stepper motor (1) is mounted on the motor seat, and an output shaft of the stepper motor (1) is drivingly connected to the rotating shaft (3).

3. The biological vaccine production and fermentation device according to claim 1, characterized in that: The sliding portion (23) has a rectangular longitudinal section.

4. The biological vaccine production and fermentation device according to claim 1, characterized in that: The two intermediate gears (5) are symmetrically arranged along the axial direction of the rotating shaft (3).

5. The biological vaccine production and fermentation device according to claim 1, characterized in that: The connection structure comprises a connection pin (28) vertically fixed to the top of the sliding rod (14); the connection pin (28) passes through the rotating rod (7) and is arranged at the bottom of the mounting portion (22); and a waist-shaped hole (24) is provided on the upper surface of the rotating rod (7) for the connection pin (28) to pass freely.

6. A method for producing and fermenting a biological vaccine, using the biological vaccine production and fermentation device according to claim 1, characterized in that: include: Adding protein stock solution into the tank body (2) through the feeding port (9), and adjusting the temperature inside the tank body (2) to allow the protein stock solution to ferment; During the fermentation process of the protein stock solution used in the vaccine, foam is generated on the surface of the protein stock solution. At this time, the rotating shaft (3) rotates to drive the mounting portion (22) to rotate, so that the rotating rod (7) rotates synchronously around the axial direction of the rotating shaft (3). During the rotation process, the multiple defoaming needles (8) on the rotating column (15) defoam the foam on the surface of the protein stock solution. During the rotation of the rotating shaft (3), the translation unit drives the rotating rod (7) to move horizontally relative to the mounting portion (22), so that the rotating column (15) drives the defoaming needle (8) to move horizontally, thereby reducing the defoaming blind area of ​​the foam on the surface of the protein stock solution.

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