A traditional Chinese medicine composition, preparation and preparation method for treating wind-cold cold in poultry

Abstract

The present invention relates to the field of traditional Chinese veterinary medicine, and specifically discloses a traditional Chinese medicine composition, preparation and preparation method for treating poultry colds. Wherein, the traditional Chinese medicine composition includes the following raw material components by mass: 10-20 parts of Ligusticum chuanxiong, 10-15 parts of Arisaema consanguineum processed, 5-15 parts of Caulis Schizonepetae dahuricae, 4-10 parts of Radix Gentianae Macrophyllae, 2-8 parts of Flos Magnoliae, 1-10 parts of Ginger, 1-10 parts of Radix Glycyrrhizae and 1-5 parts of Borneol. The present invention uses Ligusticum chuanxiong, Arisaema consanguineum processed and Caulis Schizonepetae dahuricae as monarch drugs, Radix Gentianae Macrophyllae and 1-10 parts of Radix Glycyrrhizae as ministerial drugs, Flos Magnoliae and Borneol as adjuvant drugs, and Ginger and Radix Glycyrrhizae as guiding drugs, and prepares the traditional Chinese medicine composition for treating poultry colds by combining and compatibility of each drug. The traditional Chinese medicine composition has a simple prescription and suitable cost. The traditional Chinese medicine preparation prepared by the traditional Chinese medicine composition effectively solves the problem of unsatisfactory clinical application effect of traditional Chinese veterinary medicine preparations for treating poultry colds in the prior art.

Description

Technical Field

[0001] The present invention relates to the field of traditional Chinese veterinary medicine, and specifically discloses a traditional Chinese medicine composition, a preparation and a preparation method for treating wind-cold cold in poultry. Background Art

[0002] The poultry breeding environment is generally a closed environment. Especially in winter and spring, in order to keep warm, ventilation is not allowed. Wind-cold cold in poultry is an exogenous disease caused by the recurrence of wind-cold under the condition of insufficient vital qi in the poultry body itself. It usually occurs under adverse conditions such as management mistakes, variable weather temperatures, and cold and heat temperature stress. It is a common disease of the poultry respiratory tract, and it is easy to complicate or secondary infect bacterial diseases, which can cause serious consequences and has become one of the main diseases affecting the production efficiency of poultry.

[0003] The main clinical symptoms and pathological changes of wind-cold cold in poultry: fever and aversion to cold, reduced food intake, and in severe cases, both water and food intake are reduced; listlessness, limb curling, eyes closed and drowsy, cold limbs, huddling together; feces are mostly soft or watery; sputum is mostly clear, thin and watery, clear nasal discharge, and becomes viscous as the course of the disease progresses.

[0004] The pathogenesis of wind-cold cold in poultry is mainly: wind-cold invades the lung and binds to the surface, causing the surface meridians and capillaries to contract, and yang qi cannot reach the outside. This is the main mechanism of this disease. Wind is a yang pathogen with the nature of being light and spreading, and it is easy to attack the yang position and first invade the body surface. The disease location of the body affected by wind pathogen is mostly wandering and changeable, and it reaches the interstices and meridians of the body and shows pain. Cold is a yin pathogen, which is easy to damage yang qi. The cold nature of contraction is easy to cause the body qi to converge, the interstices to close, and the sweat pores to close, resulting in fever, aversion to cold and no sweating. The cold nature of stagnation makes the qi and blood and body fluids run slowly, stagnate and block and become unsmooth, causing pain bi.

[0005] At present, for the treatment of wind-cold in poultry, Jingfang Baidu Powder is mainly used, but the clinical application effect is not ideal. Therefore, the research and development of a traditional Chinese medicine preparation that can effectively treat wind-cold cold in poultry has great practical significance for poultry breeding. Summary of the Invention

[0006] Aiming at the problem that the clinical application effect of the traditional Chinese medicine preparation for treating wind-cold cold in poultry in the prior art is not ideal, the present invention provides a traditional Chinese medicine composition, a preparation and a preparation method for treating wind-cold cold in poultry.

[0007] To achieve the above invention purpose, the present invention provides the following specific technical solutions:

[0008] A first aspect of the present invention provides a traditional Chinese medicine composition for treating colds in poultry, comprising the following raw material components in parts by weight: 10-20 parts of Ligusticum chuanxiong, 10-15 parts of processed Arisaema, 5-15 parts of Caulis Schizonepetae, 4-10 parts of Radix Achyranthis Bidentatae, 4-10 parts of Gentiana macrophyllae, 2-8 parts of Flos Magnoliae, 1-10 parts of ginger, 1-10 parts of licorice and 1-5 parts of borneol.

[0009] Compared to existing technologies, the traditional Chinese medicine composition provided by the present invention for treating poultry colds and flu has a simple formula and excellent therapeutic efficacy. The present invention screens traditional Chinese medicines and selects a combination of herbs that have the effects of dispelling cold, expelling wind and dampness, drying dampness and resolving phlegm, dispelling wind and calming convulsions, relieving lumps and dispersing masses, reducing swelling and relieving pain, and stopping bleeding and promoting blood circulation, thereby achieving the goal of effectively treating poultry colds and flus. The herbs include Ligusticum chuanxiong, Arisaema confusum processed, and Caulis Scutellariae dahuricae as monarch herbs, Rhizoma Cyperi and Radix Gentianae macrophyllae as assistant herbs, Flos Magnoliae and Borneolum Syntheticum as adjuvant herbs, and Ginger and Licorice root as guiding herbs.

[0010] Ligusticum chuanxiong: enters the bladder meridian; spicy and warm in nature; has the effect of dispersing wind, cold and dampness.

[0011] Processed Arisaema: enters the lung, liver, and spleen meridians; tastes bitter and pungent, and is warm in nature; has the effects of drying dampness and resolving phlegm, dispelling wind and calming the nerves, eliminating lumps and resolving nodules, and reducing swelling and relieving pain.

[0012] White Flower Twig: enters the Liver Channel; tastes bitter and pungent, warm in nature; has the effects of dispelling wind and dampness, promoting blood circulation and stopping bleeding.

[0013] Huanglongxu: enters the liver and kidney meridians; tastes bitter and moist, and is hot in nature; has the effects of promoting qi, eliminating wind, eliminating cold and dampness.

[0014] Gentiana macrophylla: enters the liver, gallbladder, and stomach meridians; tastes bitter and pungent, and is warm in nature; has the effects of dispelling wind and dampness, harmonizing blood and relaxing muscles, clearing heat and promoting diuresis.

[0015] Magnolia: enters the lung and stomach meridians; spicy in taste, warm in nature; has the effect of dispersing wind and cold and clearing the nasal passages.

[0016] Ginger: Enters the Lung, Spleen, and Stomach meridians; pungent in flavor and slightly warm in nature; has the effects of diaphoresis, warming the middle and stopping vomiting, and warming the lungs and relieving cough. Licorice: Enters the twelve meridians; sweet in flavor and neutral in nature; has the effects of tonifying the middle and replenishing Qi, removing phlegm and relieving cough, harmonizing the middle and relieving urgency, detoxifying, and harmonizing the properties of other herbs.

[0017] Borneol: enters the heart, spleen and lung meridians; has a light fragrance, a pungent and bitter taste, and is cool in nature; has the effects of invigorating the mind, clearing away heat and relieving pain.

[0018] The present invention utilizes the relationship between monarch, minister, assistant, and envoy drugs to combine and match the various drug components to rapidly treat sick poultry with significant efficacy. Furthermore, the pharmaceutical composition for treating colds and flu in poultry provided by the present invention is simple in formulation and affordable, providing new research ideas for treating colds and flu in poultry.

[0019] Preferably, the traditional Chinese medicine composition for treating poultry colds includes the following raw material components in parts by mass: 12-15 parts of Ligusticum chuanxiong, 12-14 parts of processed Arisaema, 8-12 parts of Caulis Schizonepetae, 5-8 parts of Radix Achyranthis Bidentatae, 5-8 parts of Gentiana macrophyllae, 3-6 parts of Magnolia officinalis, 2-8 parts of ginger, 2-8 parts of licorice and 2-5 parts of borneol.

[0020] Preferably, the traditional Chinese medicine composition for treating poultry colds includes the following raw material components in parts by mass: 12-14 parts of Ligusticum chuanxiong, 13-14 parts of processed Arisaema, 8-10 parts of Caulis Schizonepetae, 6-8 parts of Radix Achyranthis Bidentatae, 6-8 parts of Gentiana macrophyllae, 3-5 parts of Magnolia officinalis, 5-8 parts of ginger, 6-8 parts of licorice and 2-4 parts of borneol.

[0021] A second aspect of the present invention provides a traditional Chinese medicine preparation for treating poultry colds, wherein the traditional Chinese medicine preparation comprises the traditional Chinese medicine composition for treating poultry colds.

[0022] Preferably, the traditional Chinese medicine preparation further comprises an emulsifier and a preservative.

[0023] Preferably, the dosage form of the traditional Chinese medicine preparation for treating poultry colds is an oral liquid.

[0024] A third aspect of the present invention provides a method for preparing a Chinese medicine preparation for treating poultry colds, comprising the following steps:

[0025] Step 1: Weigh all raw material components except borneol according to the designed ratio, immerse in deionized water, boil 2-3 times, filter, concentrate, and cool to obtain a concentrated solution;

[0026] Step 2: dissolving borneol in alcohol to obtain an alcohol solution of borneol; adding an emulsifier to the alcohol solution of borneol and mixing uniformly to obtain a borneol emulsion;

[0027] Step 3: Evenly mix the concentrated solution and borneol emulsion, add preservatives, add water to make the drug-liquid ratio 0.8-1:1-1.1, and sterilize to obtain the traditional Chinese medicine preparation for treating poultry colds.

[0028] Preferably, in step 1, the amount of deionized water used is 10-15 times the total mass of all raw material components except borneol.

[0029] Further preferably, in step 1, the specific operation of decocting is to keep the mixture slightly boiling for 20-50 minutes after boiling.

[0030] Preferably, in step 1, the immersion time is 3-5 hours.

[0031] Preferably, in step 1, the filtration is performed using a filter cloth with a mesh size of 80-120.

[0032] Preferably, in step 1, the concentration temperature is 90-110° C., and the concentration time is 20-50 min.

[0033] Preferably, in step 2, the mass volume ratio of borneol to alcohol is 1 g:5 mL-8 mL.

[0034] Preferably, in step 2, the alcohol is anhydrous ethanol.

[0035] Preferably, in step 2, the emulsifier is Tween 80.

[0036] Preferably, in step 2, the mass ratio of the emulsifier to the alcohol solution of borneol is 1:120-5:120.

[0037] Preferably, in step three, the preservative is sodium benzoate.

[0038] Preferably, in step three, the amount of the preservative added is 0.3wt%-0.8wt% of the mass of the concentrate.

[0039] Preferably, in step three, the sterilization temperature is 115° C.-120° C., and the sterilization time is 25 min-35 min.

[0040] In summary, to address the problem that the traditional Chinese veterinary medicine preparations used in the prior art are not clinically effective in treating poultry colds, the present invention provides a traditional Chinese medicine composition, preparation, and preparation method for treating poultry colds. By utilizing the relationship between the main, secondary, auxiliary, and guiding drugs, the combination of the various drug components can rapidly treat sick poultry with significant efficacy. The traditional Chinese medicine composition for treating poultry colds provided by the present invention has a simple formulation, excellent efficacy in treating poultry colds, and low preparation cost, providing new research ideas for treating poultry colds. DETAILED DESCRIPTION

[0041] The following is a clear and complete description of the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of the present invention.

[0042] Example 1

[0043] This embodiment provides a Chinese medicine composition and preparation for treating poultry colds, the specific contents of which are as follows:

[0044] The traditional Chinese medicine composition for treating poultry colds comprises the following raw material components in parts by weight: 14g of Ligusticum chuanxiong, 13g of processed Arisaema, 10g of Caulis Scutellariae, 6g of Radix Achyranthis Bidentatae, 6g of Gentiana macrophyllae, 5g of Flos Magnoliae, 8g of fresh ginger, 8g of licorice and 3g of borneol.

[0045] The preparation method of the traditional Chinese medicine preparation for treating poultry colds comprises the following steps:

[0046] Step 1: Weigh the components except borneol according to the designed ratio and immerse them in deionized water 14 times the amount of the drug for 4 hours. After boiling, continue to keep it slightly boiling and decoct for 40 minutes. Then add water 12 times the amount of the drug, continue to keep it slightly boiling and decoct for 50 minutes. After decoction, filter with a 100-mesh filter cloth, concentrate the filtrate at 100°C for 40 minutes, and cool to room temperature to obtain a concentrated solution.

[0047] Step 2: dissolve borneol in 20 mL of anhydrous ethanol to obtain an alcohol solution of borneol, add 0.6 g of Tween 80, mix well, and obtain a borneol mixed solution;

[0048] Step 3: Evenly mix the concentrate and the borneol mixture, add 0.5 wt% of sodium benzoate by weight of the concentrate, add deionized water to make the volume to a drug-liquid ratio of 1:1, and sterilize at 116° C. for 25 min to obtain the traditional Chinese medicine preparation for treating poultry colds.

[0049] Example 2

[0050] This embodiment provides a Chinese medicine composition and preparation for treating poultry colds, the specific contents of which are as follows:

[0051] The traditional Chinese medicine composition for treating poultry colds comprises the following raw material components in parts by weight: 14g of Ligusticum chuanxiong, 14g of processed Arisaema, 8g of Caulis Scutellariae, 7g of Radix Achyranthis Bidentatae, 7g of Gentiana macrophyllae, 4g of Flos Magnoliae, 7g of fresh ginger, 7g of licorice and 2g of borneol.

[0052] The preparation method of the traditional Chinese medicine preparation for treating poultry colds comprises the following steps:

[0053] Step 1: Weigh the components except borneol according to the designed ratio and immerse them in deionized water 15 times the amount of the drug for 4 hours. After boiling, continue to keep it slightly boiling and decoct for 40 minutes. Then add water 10 times the amount of the drug, continue to keep it slightly boiling and decoct for 40 minutes. After decoction, filter with 80-mesh filter cloth, concentrate the filtrate at 100°C for 40 minutes, and cool to room temperature to obtain a concentrated solution.

[0054] Step 2: dissolve borneol in 15 mL of anhydrous ethanol to obtain an alcohol solution of borneol, add 0.3 g of Tween 80, mix well, and obtain a borneol mixed solution;

[0055] Step 3: Evenly mix the concentrate and the borneol mixture, add 0.4 wt% of sodium benzoate by weight of the concentrate, add deionized water to make the volume to a drug-liquid ratio of 1:1.1, and sterilize at 120° C. for 30 min to obtain the traditional Chinese medicine preparation for treating poultry colds.

[0056] Example 3

[0057] This embodiment provides a Chinese medicine composition and preparation for treating poultry colds, the specific contents of which are as follows:

[0058] The traditional Chinese medicine composition for treating poultry colds comprises the following raw material components in parts by weight: 13g of Ligusticum chuanxiong, 13g of processed Arisaema, 9g of Caulis Scutellariae, 7g of Radix Achyranthis Bidentatae, 7g of Gentiana macrophyllae, 4g of Flos Magnoliae, 7g of fresh ginger, 7g of licorice and 3g of borneol.

[0059] The preparation method of the traditional Chinese medicine preparation for treating poultry colds comprises the following steps:

[0060] Step 1: Weigh the components other than borneol according to the designed ratio and immerse them in deionized water 10 times the amount of the drug for 5 hours, boil and continue to keep it slightly boiling, decoct for 30 minutes, then add water 12 times the amount of the drug, boil and continue to keep it slightly boiling, decoct for 40 minutes, filter with a 120-mesh filter cloth after decoction, concentrate the filtrate at 110°C for 25 minutes, and cool to room temperature to obtain a concentrated solution;

[0061] Step 2: dissolve borneol in 15 mL of anhydrous ethanol to obtain an alcohol solution of borneol, add 0.6 g of Tween 80, mix well, and obtain a borneol mixed solution;

[0062] Step 3: Evenly mix the concentrate and the borneol mixture, add 0.8 wt% of sodium benzoate by weight of the concentrate, add deionized water to make the volume to a drug-liquid ratio of 1:1, and sterilize at 115° C. for 35 minutes to obtain the traditional Chinese medicine preparation for treating poultry colds.

[0063] Comparative Example 1

[0064] This comparative example provides a traditional Chinese medicine composition and preparation for treating colds in poultry. The difference from Example 1 is that Ligusticum chuanxiong is replaced by an equal amount of Schizonepeta tenuifolia, and Arisaema consanguineum is replaced by an equal amount of cassia twig. The other components and preparation methods remain unchanged and are not described again here.

[0065] Comparative Example 2

[0066] This comparative example provides a traditional Chinese medicine composition and preparation for treating poultry colds. The difference from Example 1 is that Ligusticum chuanxiong is replaced by an equal amount of Patchouli, and Caulis Scutellariae is replaced by an equal amount of Magnolia officinalis. The other components and preparation methods remain unchanged and will not be repeated here.

[0067] To further illustrate the technical effects of the present invention, the present invention conducted a poultry cold treatment test, the specific contents are as follows:

[0068] 1. Chicken Flock Treatment Trial

[0069] Experimental animals: 24-day-old white - feather broilers raised in a broiler farm in Hebei Province.

[0070] Symptoms: In a large group of poultry, there were symptoms such as upper body fever, lower limb coldness, aversion to cold and wind, listlessness, poor movement, and dull respiratory symptoms. Among them, the mental state was particularly sluggish in the early morning and evening when the temperature was low.

[0071] Experimental grouping: 350 broilers with obvious and similar symptoms of wind - cold cold were selected from the above diseased chicken group and divided into the first group, the second group, the third group, the fourth group, the fifth group, the sixth group and the control group, with 50 in each group. Each group was fed the same feed, and the rest of the feeding management was the same except for the different medications.

[0072] Experimental drugs: The traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Example 1 of the present invention, the traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Example 2 of the present invention, the traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Example 3 of the present invention, the traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Comparative Example 1 of the present invention, the traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Comparative Example 2 of the present invention, and Jingfang Baidu powder oral liquid.

[0073] Experimental treatment:

[0074] The first group: The traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Example 1 of the present invention was added to water according to the ratio of 1 mL: 0.5 L, mixed evenly, and used for the diseased chickens to drink water for 5 consecutive days;

[0075] The second group: The traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Example 2 of the present invention was added to water according to the ratio of 1 mL: 0.5 L, mixed evenly, and used for the diseased chickens to drink water for 5 consecutive days;

[0076] The third group: The traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Example 3 of the present invention was added to water according to the ratio of 1 mL: 0.5 L, mixed evenly, and used for the diseased chickens to drink water for 5 consecutive days;

[0077] The fourth group: The traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Comparative Example 1 of the present invention was added to water according to the ratio of 1 mL: 0.5 L, mixed evenly, and used for the diseased chickens to drink water for 5 consecutive days;

[0078] The fifth group: The traditional Chinese medicine preparation for treating wind - cold cold in poultry provided in Comparative Example 2 of the present invention was added to water according to the ratio of 1 mL: 0.5 L, mixed evenly, and used for the diseased chickens to drink water for 5 consecutive days;

[0079] The sixth group: The commercially available Jingfang Baidu powder oral liquid was added to water according to the ratio of 1 ml: 0.5 L, mixed evenly, and used for the diseased chickens to drink water for 5 consecutive days;

[0080] Control group: No drug administration.

[0081] Observation of test symptoms: During the test period, record the disease development of the test chickens in each group, and observe the mental state, appetite, and breathing of the diseased chickens.

[0082] Efficacy evaluation: Cured: After drug administration, the spirit, appetite, and drinking water basically return to normal, the lower limb body temperature returns to normal, and the symptoms of coughing, sneezing, and head shaking disappear.

[0083] Effective: After drug administration, the spirit, appetite, and drinking water have improved significantly, the lower limb body temperature returns to normal, and there are occasional symptoms of coughing, sneezing, and head shaking.

[0084] Ineffective: After drug administration, the symptoms do not improve or even the condition worsens.

[0085] The test results are shown in Table 1.

[0086] Efficacy evaluation: After drug administration, the cure rate and effective rate of the first, second, third, fourth, fifth, and sixth groups are significantly higher than those of the control group, and the cure rate of the first, second, and third groups is better than that of the fourth, fifth, and sixth groups; the ineffectiveness rate of the first, second, third, fourth, fifth, and sixth groups is significantly lower than that of the control group, and the ineffectiveness rate of the first, second, and third groups is lower than that of the fourth, fifth, and sixth groups. The specific data are shown in Table 1.

[0087] Table 1 Efficacy evaluation of chickens in each test group

[0088]

[0089] II. Treatment test on duck flocks

[0090] Test animals: Diseased Muscovy ducks raised in a duck farm in Xingtai, Hebei.

[0091] Symptoms: In large flocks of Muscovy ducks, there are symptoms such as upper body fever, lower limb cold, aversion to cold and wind, mental depression, poor movement, and dull respiratory symptoms. Among them, the mental state is particularly listless in the early morning and evening when the temperature is low.

[0092] Test grouping: Divide the diseased ducks into 7 groups, with 100 diseased ducks in each group. Each group is fed the same feed, and the other feeding management is the same except for the different drugs used.

[0093] Test drugs: The traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Example 1 of the present invention, the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Example 2 of the present invention, the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Example 3 of the present invention, the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Comparative Example 1 of the present invention, the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Comparative Example 2 of the present invention, and commercially available Jingfang Baidu powder oral liquid.

[0094] Test treatments:

[0095] Test group 1: Add the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Example 1 of the present invention into water at a ratio of 1 mL: 0.5 L, mix evenly, and use it for the diseased ducks to drink for 5 consecutive days;

[0096] Test group 2: Add the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Example 2 of the present invention into water at a ratio of 1 mL: 0.5 L, mix evenly, and use it for the diseased ducks to drink for 5 consecutive days;

[0097] Test group 3: Add the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Example 3 of the present invention into water at a ratio of 1 mL: 0.5 L, mix evenly, and use it for the diseased ducks to drink for 5 consecutive days;

[0098] Test group 4: Add the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Comparative Example 1 of the present invention into water at a ratio of 1 mL: 0.5 L, mix evenly, and use it for the diseased ducks to drink for 5 consecutive days;

[0099] Test group 5: Add the traditional Chinese medicine preparation for treating wind-cold cold in poultry provided in Comparative Example 2 of the present invention into water at a ratio of 1 mL: 0.5 L, mix evenly, and use it for the diseased chickens to drink for 5 consecutive days;

[0100] Test group 6: Add the commercially available Jingfang Baidu powder oral liquid into water at a ratio of 1 ml: 0.5 L, mix evenly, and use it for the diseased ducks to drink for 5 consecutive days;

[0101] Control group: No medicine is given.

[0102] Observation of test symptoms: During the test period, record the development of the disease conditions of the test ducks in each group, and observe the mental state, appetite, and breathing conditions of the diseased ducks.

[0103] Evaluation of curative effect: Cured: After administration, the spirit, food intake, and drinking water basically return to normal, the body temperature of the lower limbs returns to normal, and the symptoms of coughing and sneezing disappear.

[0104] Effective: After administration, the spirit, food intake, and drinking water have obvious improvement, the body temperature of the lower limbs returns to normal, and there are occasional symptoms of coughing and sneezing.

[0105] Ineffective: After administration, the symptoms do not improve or even the disease condition worsens.

[0106] Test results: Specifically shown in Table 4.

[0107] Efficacy evaluation: After administration, the cure rates and effective rates of the first, second, third, fourth, fifth, and sixth groups were significantly higher than those of the control group. The cure rates of the first, second, and third groups were better than those of the fourth, fifth, and sixth groups. The inefficiency rates of the first, second, third, fourth, fifth, and sixth groups were significantly lower than those of the control group, and the inefficiency rates of the first, second, and third groups were lower than those of the fourth, fifth, and sixth groups. The specific data are shown in Table 2.

[0108] Table 2 Test results of each test group

[0109]

[0110] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, or improvements made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition for treating wind-cold cold in poultry, characterized in that: The invention is composed of the following raw material components in parts by weight: 10-20 parts of Ligusticum chuanxiong, 10-15 parts of processed Arisaema, 5-15 parts of Caulis Scutellariae, 4-10 parts of Radix Achyranthis Bidentatae, 4-10 parts of Gentiana macrophyllae, 2-8 parts of Flos Magnoliae, 1-10 parts of ginger, 1-10 parts of licorice and 1-5 parts of borneol.

2. The traditional Chinese medicine composition for treating wind-cold cold in poultry according to claim 1, wherein: The invention is composed of the following raw material components in parts by weight: 12-15 parts of Ligusticum chuanxiong, 12-14 parts of processed Arisaema, 8-12 parts of Caulis Scutellariae, 5-8 parts of Radix Achyranthis Bidentatae, 5-8 parts of Radix Gentianae, 3-6 parts of Flos Magnoliae, 2-8 parts of fresh ginger, 2-8 parts of licorice and 2-5 parts of borneol.

3. The traditional Chinese medicine composition for treating wind-cold cold in poultry according to any one of claims 1 or 2, characterized in that: The invention is composed of the following raw material components in parts by weight: 12-14 parts of Ligusticum chuanxiong, 13-14 parts of processed Arisaema, 8-10 parts of Caulis Scutellariae, 6-8 parts of Radix Achyranthis Bidentatae, 6-8 parts of Radix Gentianae, 3-5 parts of Flos Magnoliae, 5-8 parts of fresh ginger, 6-8 parts of Radix Glycyrrhizae and 2-4 parts of borneol.

4. A traditional Chinese medicine preparation for treating wind-cold cold in poultry, characterized in that: The invention relates to a Chinese medicinal composition for treating poultry colds according to any one of claims 1 to 3.

5. The traditional Chinese medicine preparation for treating wind-cold cold in poultry according to claim 4, characterized in that: The traditional Chinese medicine preparation also includes an emulsifier and a preservative.

6. The traditional Chinese medicine preparation for treating wind-cold cold in poultry as described in claim 5, characterized in that: The dosage form of the Chinese medicine preparation is oral liquid.

7. A preparation method of the traditional Chinese medicine preparation for treating wind-cold cold in poultry according to claim 5, characterized in that: The steps include: Step 1: Weigh all raw material components except borneol according to the designed ratio, immerse in deionized water, boil 2-3 times, filter, concentrate, and cool to obtain a concentrated solution; Step 2: dissolving borneol in alcohol to obtain an alcohol solution of borneol; adding an emulsifier to the alcohol solution of borneol and mixing uniformly to obtain a borneol emulsion; Step 3: Evenly mix the concentrated solution and borneol emulsion, add preservatives, add water to make the drug-liquid ratio 0.8-1:1-1.1, and sterilize to obtain the traditional Chinese medicine preparation for treating poultry colds.

8. The preparation method of the traditional Chinese medicine preparation for treating wind-cold cold in poultry according to claim 7, characterized in that: In step 1, the amount of deionized water used is 10-15 times the total mass of the raw material components except borneol; and / or In step 1, the immersion time is 3-5 hours; and / or In step 1, the concentration temperature is 90-110° C., and the concentration time is 20-50 min.

9. The preparation method of the traditional Chinese medicine preparation for treating wind-cold cold in poultry according to claim 7, characterized in that: In step 2, the mass volume ratio of borneol to alcohol is 1g:5mL-8mL; and / or In step 2, the alcohol is anhydrous ethanol; and / or In step 2, the emulsifier is Tween 80; and / or In step 2, the mass ratio of the emulsifier to the alcohol solution of borneol is 1:120-5:120; and / or In step 3, the preservative is sodium benzoate; and / or In step 3, the amount of the preservative added is 0.3wt%-0.8wt% of the concentrate mass.

10. The preparation method of the traditional Chinese medicine preparation for treating wind-cold cold in poultry as claimed in claim 7, characterized in that: In step 3, the sterilization temperature is 115° C.-120° C., and the sterilization time is 25 min-35 min.

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