Herbicidal composition containing icafolin and use thereof

Abstract

The application belongs to the technical field of pesticide weeding, and discloses a weeding composition containing icafolin and application thereof. The weeding composition contains active ingredient A and active ingredient B. The active ingredient A is icafolin, the active ingredient B is any one of benzenesulfonamides or thiophenesulfonamides, and the mass ratio of the active ingredient A to the active ingredient B is 1:2-200:4.5. The weeding composition provided by the application has high weeding activity, and the mixture of the two has superimposition effect, complementary mechanism, and an expanded weed spectrum. The weeding composition has good weed control effect in corn fields, wheat fields, peanut fields and soybean fields.

Description

Technical Field

[0001] This invention belongs to the field of weed control technology and discloses a weed control composition containing icafolin and its application. Background Technology

[0002] Bensulfuron-methyl is a systemic selective sulfonylurea herbicide. After being absorbed by the roots, stems, and leaves of plants, it is rapidly translocated to inhibit the activity of acetolactate synthase (ALS), thus hindering the biosynthesis of valine and isoleucine, thereby suppressing weed growth. It can be used to control broadleaf weeds such as thistle, chickweed, shepherd's purse, lambsquarters, knotweed, amaranth, field mustard, sedge, and sedge in wheat, barley, and other crop fields.

[0003] Thifensulfuron-methyl belongs to the sulfonylurea herbicide class and is mainly used on crops such as cereals, soybeans, and corn to control a variety of annual and perennial broadleaf weeds. It is an acetolactate synthase (ALS) inhibitor, which inhibits the biosynthesis of valine, leucine, and isoleucine, thereby preventing cell division. Sensitive weeds stop growing rapidly after being treated with this herbicide.

[0004] Farmland weeds are an important biological component of the agricultural ecosystem. Weeds constantly adapt to changes in climate, crops, and agricultural management, and can directly or indirectly cause losses in crop yield and quality. Wheat is my country's second largest food crop after rice and the world's highest-yielding crop, its production playing a vital role in ensuring national food security. During wheat production, pests, diseases, and weeds cause significant damage, often resulting in severe economic losses. The widespread occurrence of weeds in wheat fields is a global problem. In recent years, with adjustments to the planting structure and changes in farming systems, the population changes and community succession of weeds in wheat fields have accelerated. Some minor weeds have gradually become major weeds, especially grassy weeds. In some areas, grassy weeds such as wild oats, barnyard grass, and jointed goatgrass are causing severe damage to wheat fields, resulting in yield losses of around 20%, and in some individual fields even exceeding 50%. At the same time, noxious broadleaf weeds in wheat fields are also increasing year by year, with cleavers, eupatorium fortunei, barnyard grass, chickweed, and speedwell spreading in some areas. In response to changes in the weed community in wheat fields, there is an urgent need for herbicides that can control both grassy weeds and noxious broadleaf weeds. Summary of the Invention

[0005] Based on the above, the purpose of this invention is to provide a herbicidal composition that has excellent control effect on common weeds in wheat fields. This herbicidal composition has a broad spectrum of weed control, is safe for wheat growth, and has good rapid effect and long-lasting effect.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a herbicidal composition containing icafolin, wherein the herbicidal composition comprises active ingredient A and active ingredient B, wherein active ingredient A is icafolin, and active ingredient B is either bensulfuron-methyl or thifensulfuron-methyl, wherein the mass ratio of active ingredient A to active ingredient B is 1:2 to 200:4.5, or any value within the above range.

[0007] Furthermore, the mass ratio of active ingredient A to active ingredient B is 1:2 to 200:9, or any value within the above range.

[0008] Furthermore, the active ingredient B is benzyl sulfide, and the mass ratio of the active ingredient A to the active ingredient B is 50:18 to 200:9, or any value within the above range.

[0009] Furthermore, the active ingredient B is benzyl sulfide, and the mass ratio of active ingredient A to active ingredient B is any value between 50+4.5 (50:4.5), 50+9 (50:9), 50+18 (25:9), 100+4.5 (100:4.5), 100+9 (100:9), 100+18 (50:9), 200+9 (200:9), 200+18 (100:9) or the above values;

[0010] Furthermore, the active ingredient B is thifensulfuron, and the mass ratio of the active ingredient A to the active ingredient B is 25:16 to 25:1, or any value between the above values.

[0011] Furthermore, the active ingredient B is thifensulfuron, and the mass ratio of active ingredient A to active ingredient B is 50+8 (25:4), 50+16 (25:8), 50+32 (25:16), 100+8 (25:2), 100+16 (25:4), 100+32 (25:8), 200+8 (25:1), 200+16 (25:2), 200+32 (25:4), or any value between the above values;

[0012] Furthermore, the herbicidal composition, in addition to the active ingredient, also contains pesticide-acceptable auxiliary ingredients, which are one or more of the following: wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists, binders, fillers, or carriers.

[0013] Further, the wetting agent is one or more of the following: alkylbenzene sulfonate, alkylnaphthalene sulfonate, lignin sulfonate, sodium dodecyl sulfate, sodium dioctyl succinate sulfonate, α-olefin sulfonate, alkylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, alkylphenol ethoxylate, fatty alcohol ethoxylate, sodium fatty alcohol polyoxyethylene ether sulfate, silkworm excrement, soapberry powder, soapberry powder, SOPA, detergent, emulsifier 2000 series, and wetting and penetrating agent F; and / or

[0014] Further, the dispersant is one or more of the following: lignin sulfonate, alkylnaphthalene sulfonate formaldehyde condensate, naphthalene sulfonate, tristyrylphenol ethoxylate phosphate, fatty alcohol ethoxylate, alkylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether methyl ether condensate sulfate, fatty amine polyoxyethylene ether, glycerol fatty acid ester polyoxyethylene ether, polycarboxylates, polyacrylic acids, phosphates, EO-PO block copolymers, and EO-PO graft copolymers; and / or

[0015] Further, the emulsifier is one or more of the following: calcium dodecylbenzenesulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, phenethylphenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styrene-phenol polyoxyethylene ether, castor oil polyoxyethylene ether, and alkylphenol ether phosphate; and / or

[0016] Further, the thickener is one or more selected from xanthan gum, organobentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose, and silica; and / or

[0017] Further, the disintegrant is one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid, and tartaric acid; and / or

[0018] Furthermore, the antifreeze is one or more selected from alcohols, alcohol ethers, chlorinated hydrocarbons, and inorganic salts; and / or

[0019] Furthermore, the defoamer is C 10 -C 20 Saturated fatty acid compounds, silicone oil, silicone compounds, C8-C 10 One or more of the fatty alcohols; and / or

[0020] Further, the preservative is one or more selected from propionic acid, sodium propionate, sorbic acid, sodium sorbate, potassium sorbate, benzoic acid, sodium benzoate, sodium p-hydroxybenzoate, methyl p-hydroxybenzoate, Kathon, and 1,2-benzisothiazolin-3-one; and / or

[0021] Further, the stabilizer is one or more of the following: disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-cresol, triethanolamine oleate, epoxidized vegetable oil, kaolin, bentonite, attapulgite, silica, talc, montmorillonite, and starch; and / or

[0022] Furthermore, the synergist is selected from synergistic phosphorus, synergistic ether; and / or

[0023] Furthermore, the filler is a solvent, filler, or carrier; and / or

[0024] Further, the solvent is one or more of benzene, toluene, xylene, mesitylene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethylformamide, cyclohexanone, hydrocarbon carbonate, diesel oil, solvent oil, vegetable oil, vegetable oil derivatives, and water; and / or

[0025] Furthermore, the carrier is one or more of the following: ammonium salt, ground natural mineral, ground artificial mineral, silicate, resin, wax, solid fertilizer, water, organic solvent, mineral oil, vegetable oil, and vegetable oil derivatives; and / or

[0026] Furthermore, the formulation of the herbicidal composition is prepared in the form of wettable powder, water-dispersible granules, granules, dispersible oil suspension, suspension, water emulsion, microemulsion, suspension emulsion or emulsifiable concentrate;

[0027] Furthermore, the formulation of the herbicidal composition is prepared as a wettable powder, water-dispersible granules, dispersible oil suspension, or emulsifiable concentrate.

[0028] Furthermore, the production processes for various dosage forms of the composition are existing known technologies and will not be described in detail here.

[0029] The present invention also discloses the application of the herbicidal composition described above for the control of unwanted weeds;

[0030] Furthermore, the unwanted weeds grow in wheat fields, corn fields, peanut fields, or soybean fields;

[0031] Furthermore, the unwanted weed growing area is a wheat field;

[0032] Furthermore, the herbicidal composition is applied to unwanted weeds and / or their growing areas.

[0033] Compared with the prior art, the present invention has the following advantages:

[0034] 1. The herbicidal composition of the present invention has high herbicidal activity and its control effect is significantly higher than that of any single agent. The combination of the two has a synergistic effect.

[0035] 2. The herbicidal composition of the present invention has complementary mechanisms of action, which can broaden the spectrum of weed control and has good control effect on common grasses and broadleaf weeds in wheat fields.

[0036] 3. The herbicidal composition of the present invention is safe for wheat, has good rapid effect and long-lasting effect. Detailed Implementation

[0037] To better understand the essence of the present invention, the following embodiments are used to further illustrate the content of the present invention, but they should not be regarded as limitations on the present invention. The following description is only used to explain the present invention. Any modifications, substitutions or improvements made without departing from the spirit and principles of the present invention shall fall within the scope of protection claimed by the present invention.

[0038] The preparation examples prepared below have all met the quality and technical indicators required for the corresponding preparations after testing, and the resulting preparations are qualified preparations recognized in this field.

[0039] Example of formulation preparation.

[0040] Preparation Example 1: 68% icafolin·bensulfuron wettable powder (50:18)

[0041] Formula composition: 50% icafolin, 18% benzyl sulfonate, 9% sodium lignosulfonate, 5% ethylene glycol oxyethylene polyoxypropylene ether, 2% sodium dodecyl sulfate, 5% dispersant NNO, 5% silica, kaolin to make up the balance;

[0042] Preparation method: According to the formula composition, the active ingredients, dispersant, wetting agent and filler are mixed and stirred evenly in a stirring tank. The mixture is then pulverized and mixed evenly multiple times by an air jet mill to prepare the wettable powder of the composition of the present invention.

[0043] Preparation Example 2: 29% icafolin·bensulfuron-methyl water-dispersible granules (25:4)

[0044] Formula composition: 25% icafolin, 4% benzyl sulfonate, 8% sodium lignosulfonate, 3% BX (a type of lignosulfonate), 8% naphthalene sulfonate formaldehyde condensate, 5% white sugar, kaolin to make up the balance;

[0045] Preparation method: According to the formula ratio, add the active ingredients to the carrier, and add surfactants and other functional additives to it. Mix, and after air jet milling, add 10-25% water. Then knead, granulate, dry and sieve to obtain water-dispersible granules; or spray water, granulate and dry the pulverized powder in a fluidized bed granulator, and then sieve to obtain water-dispersible granules.

[0046] Preparation Example 3: 23% icafolin·bensulfuron-methyl dispersible oil suspension (22:1)

[0047] Formula composition: 22% icafolin, 1% benzyl sulfonate, 3% lignin sulfonate, 12% triphenylethylphenol polyoxyethylene ether, 3% sorbitol polyoxyethylene ether, 2% calcium dodecylbenzenesulfonate, 2% silica, 1% organobentonite, 20% 200# solvent oil, methyl oleate to make up the balance;

[0048] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in the reaction vessel in sequence, oil is added and mixed evenly, and then subjected to high-speed shearing, wet sand milling and finally homogenization filtration to obtain the dispersible oil suspension product.

[0049] Preparation Example 4: 25% icafolin·thifensulfuron wettable powder (4:1)

[0050] Formula composition: 20% icafolin, 5% thifensulfonium, 8% sodium lignosulfonate, 5% dispersant NNO, 2% sodium dodecyl sulfate, kaolin to make up the balance;

[0051] Preparation method: According to the formula composition, the active ingredients, dispersant, wetting agent and filler are mixed and stirred evenly in a stirring tank. The mixture is then pulverized and mixed evenly multiple times by an air jet mill to prepare the wettable powder of the composition of the present invention.

[0052] Preparation Example 5: 27% icafolin·thifensulfuron water-dispersible granules (8:1)

[0053] Formula composition: 24% icafolin, 3% thifensulfonium, 10% sodium lignosulfonate, 5% sodium polycarboxylate, 2% sodium dodecyl sulfate, 5% silica, 30% starch, kaolin to make up the balance;

[0054] Preparation method: According to the formula ratio, add the active ingredients to the carrier, and add surfactants and other functional additives to it. Mix, and after air jet milling, add 10-25% water. Then knead, granulate, dry and sieve to obtain water-dispersible granules; or spray water, granulate and dry the pulverized powder in a fluidized bed granulator, and then sieve to obtain the product.

[0055] Preparation Example 6: 7% icafolin·thifensulfuron emulsifiable concentrate (9:5)

[0056] Formula composition: 4.5% icafolin, 2.5% thifensulfuron, 20% propylene carbonate, 8% phenethylphenol polyoxyethylene polyoxypropylene ether, 2% calcium dodecylbenzenesulfonate, 8% cyclohexanone, methyl oleate to make up the balance;

[0057] Preparation method: According to the formula ratio, the measured active ingredients, solvents and co-solvents are added to the mixing tank and stirred to dissolve them. Then, the emulsifier is added, and the remaining solvent is used to make up the balance. The mixture is stirred evenly in the mixing tank and filtered to obtain the emulsifiable oil required by the present invention.

[0058] Example 1: Indoor activity assay.

[0059] Test basis: The test refers to NY / T 1155.4-2006 "Guidelines for Indoor Bioactivity Determination of Pesticides - Herbicides Part 4: Activity Determination Test - Foliar Spray Method"; NY / T 1155.7-2006 "Guidelines for Indoor Bioactivity Determination of Pesticides - Herbicides Part 7: Determination of Combined Effects of Mixtures".

[0060] Experimental equipment: light incubator, controllable quantitative spray tower, electronic balance, pots, beakers, pipettes, etc.

[0061] Experimental targets: wild oats, wild oats, shepherd's purse, and wheatgrass.

[0062] Test reagents: Icapolin technical grade, bensulfuron technical grade, and thifensulfuron technical grade.

[0063] Test soil: The test used air-dried soil with organic matter content ≤3%, neutral pH, good permeability, and sieved.

[0064] Test material preparation: Fill pots with the above-mentioned test soil to 4 / 5 full. Water thoroughly by bottom-drip irrigation until the soil is completely moist. Evenly sow the pretreated weed seeds on the soil surface, covering them with 0.5cm–2cm of soil depending on seed size. After sowing, transplant the pots into a greenhouse for conventional cultivation. Once the weeds emerge, thin them to ensure uniform plant density. Based on the characteristics of herbicides, select appropriate leaf age for spraying.

[0065] Drug preparation: Dissolve the test drug in a suitable solvent, then dilute it with a 0.1% Tween 80 aqueous solution. Based on the drug activity, set up 5 series of dosages.

[0066] Chemical treatment: Foliar spraying was performed in sequence from low to high doses according to the experimental design. Each treatment was replicated four times, and a control group without the chemical treatment was included.

[0067] After treatment, the sample material was allowed to air dry naturally before being transferred to a greenhouse for routine cultivation. During the experiment, water was replenished by drip irrigation from the bottom of the pots.

[0068] After treatment, the plants continued to be cultivated in the greenhouse. The weed control effect of each treatment was observed regularly. The fresh weight of the surviving weeds above ground was weighed 14 days after application, and the actual fresh weight control effect was calculated.

[0069] The calculation formula is as follows:

[0070] Fresh weight control efficacy E = (Fresh weight of control area - Fresh weight of treatment area) × 100 / Fresh weight of control area

[0071] Theoretical control efficacy E0 of the mixture = weed control efficacy of herbicide A at dosage P + weed control efficacy of herbicide B at dosage Q - weed control efficacy of herbicide A at dosage P × weed control efficacy of herbicide B at dosage Q ÷ 100

[0072] Evaluation criteria for the combined effects of mixed drugs:

[0073] E-E0 > 10% indicates a synergistic effect, E-E0 < -10% indicates an antagonistic effect, and E-E0 between ±10% indicates an additive effect.

[0074] Experimental results:

[0075]

[0076]

[0077]

[0078]

[0079] The experimental results are shown in Tables 1-4. When icafolin and bensulfuron were used together to control common weeds in wheat fields, the combined effect in the laboratory was additive or synergistic. The optimal dosages of icafolin and bensulfuron were 50+4.5 (50:4.5), 50+9 (50:9), 50+18 (25:9), 100+4.5 (100:4.5), 100+9 (100:9), 100+18 (50:9), 200+9 (200:9), and 200+18 (50:9), respectively. At a ratio of 8 (100:9), the combined action of icafolin and bensulfuron-methyl in the laboratory showed a synergistic effect on common weeds in wheat fields, namely, when the mass ratio of icafolin to bensulfuron-methyl was 50:18 to 200:9 (the effective dosage of icafolin in the herbicidal composition was 50 to 200 g / ha, and the effective dosage of bensulfuron-methyl was 4.5 to 18 g / ha), the combined action of icafolin and bensulfuron-methyl in the laboratory showed a synergistic effect on common weeds in wheat fields, namely, icafolin, shepherd's purse, and wild oats.

[0080]

[0081]

[0082]

[0083]

[0084] The experimental results are shown in Table 5-8. When icafolin and thifensulfuron were used together to control common weeds in wheat fields, the combined effect was synergistic within a suitable mass ratio range. The optimal dosages of icafolin and thifensulfuron were 50+8 (25:4), 50+16 (25:8), 50+32 (25:16), 100+8 (25:2), 100+16 (25:4), 100+32 (25:8), 200+8 (25:1), and 200+16 (25:1). 2) When the ratio of icafolin to thifensulfuron is 25:16 to 25:1 (the effective dosage of icafolin in the herbicide composition is 50 to 200 g / ha and the effective dosage of thifensulfuron is 8 to 32 g / ha), the combined effect of icafolin and thifensulfuron in the indoor environment is synergistic.

[0085] Example 2: Field efficacy trial.

[0086] Experimental basis: The experiment was conducted in accordance with GB / T 17980.41-2000 "Field Efficacy Test Guidelines (I) Herbicides for the Control of Weeds in Wheat Crops".

[0087] Experimental site: Wheat field in Zhangmatun Village, Licheng District, Jinan City. The soil in the experimental site is brown soil with moderate fertility. The cultivation conditions in all experimental plots are uniform and consistent, which is in line with local scientific agricultural practices.

[0088] Test reagents: 7% icafolin•thifensulfuron emulsifiable concentrate (9:5), 29% icafolin•bensulfuron water dispersible granules (25:4), 10% benzsulfuron wettable powder, 75% thifensulfuron water dispersible granules, 35% icafolin wettable powder, and water control.

[0089] Cell area: Each experimental cell area is 30m² 2 Each treatment was repeated 4 times, and the different treatment plots were arranged in a randomized block design.

[0090] Application time: Wheat was sown on October 4, 2022, and pesticide spraying was carried out on November 14, 2022. The weather was sunny on the day of application, and no adverse weather conditions affecting the experimental results occurred after application. The weed population in the experimental field was surveyed before application. Absolute values ​​were measured 15 and 45 days after application. Four points were randomly selected from each plot, and each point was surveyed at a depth of 0.25 m. 2The number of weeds was recorded, and the weed control efficacy per plant was calculated. 45 days after the application, four weeds were collected from the plot, their fresh weight was measured, and the fresh weight control efficacy was calculated.

[0091] Safety investigation: Visually inspect wheat 15 and 45 days after application to determine whether the tested pesticide caused symptoms of pesticide damage such as necrotic spots, yellowing, deformity, and seedling death.

[0092] Methods for calculating efficacy and yield:

[0093]

[0094] Experimental results and analysis:

[0095]

[0096] The test results in the table above show that the herbicidal composition of the present invention has good control effects on common broadleaf weeds and grass weeds in wheat fields. Fifteen days after application, the control efficacy of each compound formulation against the grass weed *Alopecurus aequalis* was significantly better than that of each single compound formulation. The herbicidal composition of the present invention broadens the weed control spectrum, and no adverse effects on wheat growth were found in any of the compound formulations throughout the entire test, indicating its safety for wheat.

[0097] Although the present invention has been described in detail above with general description and specific embodiments, some modifications or improvements can be made to it, which will be obvious to those skilled in the art. Therefore, all such modifications or improvements made without departing from the spirit of the present invention are within the scope of protection claimed by the present invention.

Claims

1. A herbicidal composition containing icafolin, characterized in that, The herbicidal composition comprises active ingredient A and active ingredient B, wherein active ingredient A is icafolin and active ingredient B is either bensulfuron-methyl or thifensulfuron-methyl. The active ingredient B is benzyl sulfide, and the mass ratio of active ingredient A to active ingredient B is 50:18 to 200:9; The active ingredient B is thifensulfuron, and the mass ratio of active ingredient A to active ingredient B is 25:16 to 25:

1.

2. The herbicidal composition according to claim 1, characterized in that, The active ingredient B is benzylsulfuron, and the mass ratio of active ingredient A to active ingredient B is 50:4.5, 50:9, 50:18, 100:4.5, 100:9, 100:18, 200:9, or 200:18; the active ingredient B is thifensulfuron, and the mass ratio of active ingredient A to active ingredient B is 50:8, 50:16, 50:32, 100:8, 100:16, 100:32, 200:8, 200:16, or 200:

32.

3. The herbicidal composition according to claim 1, characterized in that, In addition to the active ingredient, the herbicidal composition contains pesticide-acceptable auxiliary ingredients, which are one or more of the following: wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists, binders, fillers, or carriers.

4. The herbicidal composition according to claim 1, characterized in that, The formulation of the herbicidal composition is prepared in the form of wettable powder, water-dispersible granules, granules, dispersible oil suspension, suspension, water emulsion, microemulsion, suspension emulsion or emulsifiable concentrate.

5. The herbicidal composition according to claim 4, characterized in that, The formulation of the herbicidal composition is prepared as a wettable powder, water-dispersible granules, dispersible oil suspension, or emulsifiable concentrate.

6. The herbicidal composition according to any one of claims 1-5 for the control of unwanted weeds.

7. The application according to claim 6, characterized in that, The unwanted weeds are growing in wheat fields, corn fields, peanut fields, or soybean fields.

8. The application according to claim 7, characterized in that, The unwanted weeds were found in wheat fields.

9. The application according to claim 7, characterized in that, Apply the herbicidal composition to unwanted weeds and / or their growing areas.

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