A sterile filtration device for earthworm fibrinolytic enzyme

Abstract

The present invention discloses a sterile filtration device for earthworm fibrinolytic enzyme, which belongs to the technical field of enzyme preparation processing, and comprises a filter kettle, wherein a kettle cover is provided on the top of the filter kettle, and a liquid inlet pipe is provided on the top of the kettle cover, a liquid discharge port is connected to the bottom of the filter kettle, and a plurality of filter membrane mechanisms are arranged in an array through the inner cavity of the filter kettle, and the enzyme preparation is sterile filtered through the filter membrane mechanisms in sequence. In the present invention, the driving ring and the rotating disk are driven to rotate by the rotation of the driving shaft, and the rotation of the rotating disk can be pressed away from the unfolding disk, and the plurality of movable rotating disks can be unfolded by the elastic cover while pulling the inner membrane core to unfold, and the contact range with the lateral flushing liquid is increased by the unfolded membrane core, which is conducive to fully flushing the blocked membrane core, and the durable life is extended by the flushable filter membrane mechanism, and the enzyme preparation is filtered by the membrane core that can be controlled by contraction, so as to avoid the accumulation of enzyme preparation due to the gap unfolding and affecting the filtering effect.

Description

Technical Field

[0001] The invention belongs to the technical field of enzyme preparation processing, and in particular relates to a sterile filtering device for earthworm fibrinolytic enzyme. Background Art

[0002] Earthworm fibrinolytic enzyme, also known as lumbrokinase or earthworm powder enzyme (EPE), is a complex enzyme preparation extracted from earthworms. It belongs to the fibrinolytic enzyme class, has high proteolytic activity, and has typical fibrinolytic activity. Earthworm fibrinolytic enzyme can directly act on fibrin, promote the dissolution of thrombus, and thus play an anti-thrombotic role. During the extraction process of earthworm fibrinolytic enzyme, the crude enzyme solution needs to be purified and modified, and large particles of impurities need to be filtered to remove.

[0003] The Chinese patent application with application number CN112090132A discloses an anti-clogging filtering device for enzyme preparation production, including a box body, a top plate, a first motor, a purification device body, a pretreatment device, a rotating device, a sealing device and a discharge pipe. The present invention is equipped with a pretreatment device, and a pulley is driven by a motor to move, so that the internal connecting shaft drives the scattering piece to quickly scatter the passing materials to prevent the agglomerated materials from entering the box body; a sealing device is arranged at the upper left end of the box body, and the sealing device can realize the sealing of the bottom inlet under the drive of the motor to prevent the cleaning During the cleaning process, impurities enter the purification device; a rotating device is installed at the left end of the box, and an intermittent rotating mechanism is arranged in the rotating device. The intermittent rotating mechanism can make the toothed belt wheel group move to drive the three groups of filters in the box to realize intermittent rotation, so as to realize efficient and stable cleaning and quickly remove the attached impurities. However, in actual use, the impurities in the enzyme solution are easy to adhere to the filter element, affecting the filtering and cleaning effect. The filter element needs to be flushed, and the composite compressed filter element cannot flush the adhered debris well during flushing, and it is easy to mix in the enzyme preparation after clogging. There is room for improvement. Summary of the invention

[0004] The purpose of the present invention is to solve the problem that the composite compressed filter element cannot well flush the adhered debris during flushing, and is easily mixed in the enzyme preparation after clogging, thus affecting the purity of the enzyme preparation, and to propose a sterile filtration device for earthworm fibrinolytic enzyme.

[0005] In order to achieve the above object, the present invention adopts the following technical solutions:

[0006] A sterile filtration device for earthworm fibrinolytic enzyme, comprising a filter kettle, a kettle cover is provided on the top of the filter kettle, a liquid inlet pipe is provided on the top of the kettle cover, a liquid discharge port is connected to the bottom of the filter kettle, a plurality of filter membrane mechanisms are arranged in an array through the inner cavity of the filter kettle, enzyme preparation passes through the filter membrane mechanisms in sequence for sterile filtration, a filter membrane control mechanism is provided in the inner cavity of the filter membrane mechanism, and the filter membrane mechanism is driven to expand the membrane layer spacing through the filter membrane control mechanism, two sets of flushing valve pipes are provided on the outer side wall of the filter kettle, and the flushing valve pipes are connected to an external backwashing pump body;

[0007] A liquid distributing mechanism is provided on the top of the filtering kettle, and the liquid distributing mechanism is located on the top of the filter membrane mechanism. The liquid distributing mechanism is connected to the liquid inlet of the top kettle cover to control the aseptic injection of the enzyme preparation.

[0008] As a further description of the above technical solution:

[0009] The filter membrane mechanism includes an upper membrane layer and a lower membrane layer, and a plurality of membrane cores are equidistantly arranged around the upper membrane layer and the lower membrane layer along the axis, and the inner side of the membrane core is connected to one side of the filter membrane control mechanism at the corresponding position, and the membrane core is unfolded by pulling the membrane control mechanism to unfold.

[0010] As a further description of the above technical solution:

[0011] The filter membrane control mechanism includes a plurality of rotating disks and unfolding disks corresponding to each other, the rotating disk and the unfolding disk are rotatably connected with elastic covers on their outer sides, the two sides of the elastic covers are respectively connected with the two sides of the membrane core, the space between the rotating disk and the unfolding disk is closed by the elastic covers, a plurality of extrusion blocks are equidistantly connected along the axis to one side of the rotating disk corresponding to the unfolding disk, a plurality of track grooves corresponding to the extrusion blocks are equidistantly opened along the axis to one side of the unfolding disk corresponding to the rotating disk, the rotation of the rotating disk drives the extrusion blocks to rotate in the track grooves, drives the unfolding disk to move and pulls the membrane core to unfold.

[0012] As a further description of the above technical solution:

[0013] A plurality of rotating disk cavities are provided with card slots, in which drive rings are carded, and a drive shaft is rotatably connected between the plurality of drive rings, and the drive shaft is rotatably connected to the bottom side of the inner cavity of the filter kettle, and the rotation of the rotating disk is controlled by the rotation of the drive shaft.

[0014] As a further description of the above technical solution:

[0015] Force blocks are connected to both sides of the inner cavity of the groove body at the top end of the driving shaft, an electric push rod is connected to the bottom of the liquid distribution mechanism, an extrusion rod is connected to the bottom of the electric push rod, and extrusion balls are connected to both sides of the bottom of the extrusion rod through the rod body. The force blocks are squeezed by the extrusion balls to rotate the driving shaft, and the driving shaft is rotatably connected to the bottom side of the inner cavity of the filter kettle through a rewinding bearing.

[0016] As a further description of the above technical solution:

[0017] The liquid distributing mechanism comprises a liquid distributing hood, a plurality of liquid draining grooves are arranged at equal intervals around the bottom of the liquid distributing hood along the axis, a liquid distributing hood is arranged in the inner cavity, the liquid distributing hood comprises a plurality of spiral liquid guiding plates arranged obliquely, and a moving ring is slidably connected to the top of the liquid distributing hood, a liquid seat is installed on both sides of the top of the moving ring through a pushing cylinder, and a shielding hood is connected between the liquid seat and the moving ring, and the top chamber of the liquid seat is connected to the bottom side of the kettle cover;

[0018] The inner cavity of the liquid seat is slidably connected with a closed ring, and the bottom of the closed ring is equidistantly connected with a plurality of blocking blocks along the axis. The bottom of the liquid seat is provided with leakage holes at positions corresponding to the blocking blocks, and a closed seat is provided in the leakage hole. The blocking blocks are sealed and embedded in the closed seat.

[0019] As a further description of the above technical solution:

[0020] The cross-sectional shape of the inner cavity of the closing seat is conical, and the cross-sectional shape of the blocking block is conical, and the leakage gap is opened by moving the blocking block upward and separating from the closing seat.

[0021] As a further description of the above technical solution:

[0022] A accommodating groove is provided at the position of the liquid seat in the inner cavity of the movable ring, and a plurality of liquid introduction rollers are equidistantly connected to the inner cavity of the accommodating groove through a plate body along the axis, and a through groove is provided at the bottom of the inner cavity of the accommodating groove corresponding to the position of the liquid introduction roller, and the liquid introduction roller corresponds to the bottom of the sealing block, and the liquid introduction roller is driven by the movement of the movable ring to push the sealing block to separate from the closing seat.

[0023] As a further description of the above technical solution:

[0024] Guide holes are provided on both sides of the bottom of the closed ring, and guide rods are slidably connected in the guide holes, and the guide rods are connected to the bottom of the liquid seat inner cavity. A first spring is sleeved on the outer wall of the guide rod, and the two ends of the first spring are respectively connected to the corresponding positions of the liquid seat and one side of the closed ring.

[0025] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are:

[0026] 1. In the present invention, after the enzyme preparation is injected into the liquid distribution mechanism through the covering top feed port, the liquid distribution mechanism can evenly distribute the enzyme preparation solution on the top of the filter membrane structure for filtration, and then the driving ring and the rotating disk are driven to rotate by the driving shaft. The rotation of the rotating disk can squeeze the unfolding disk away, and multiple movable rotating disks can be unfolded by the elastic cover while pulling the inner membrane core to unfold. The unfolded membrane core increases the contact range with the lateral flushing liquid, which is conducive to fully flushing the clogged membrane core, and the durable life is extended by the flushable filter membrane mechanism. The enzyme preparation is filtered by the retractable and controllable membrane core to avoid the accumulation of enzyme preparations due to gap expansion that affects the filtration effect.

[0027] In the present invention, after the bottom enzyme preparation is filtered in the filter membrane structure, the cylinder can be controlled to shorten the pulling of the moving ring, and the movement of the moving ring can drive the inner liquid introduction roller to move upward. The upward movement of the liquid introduction roller can push the sealing block to separate from the closing seat and open the leakage gap, so that the sealing block can be driven by the sliding of the closing ring to seal the liquid seat, which is beneficial to quickly control the feeding of the enzyme preparation to the filter membrane mechanism, facilitate the feeding control during filtration, facilitate the adjustment of the filtration waiting time of the enzyme preparation, improve the filtration adaptability, reduce the contamination of the enzyme preparation in the filter kettle into the feed pipe, meet the needs of continuous production, and the multiple liquid outlets arranged in a ring at the bottom of the liquid seat can cooperate with the bottom liquid distribution cover to improve the uniformity of liquid distribution.

[0028] In the present invention, after the enzyme preparation is introduced into the containing tank and enters the bottom liquid distribution cover, the liquid guide plate in the liquid distribution cover can evenly disperse the enzyme preparation into the bottom liquid distribution cover after receiving the enzyme preparation, and the drainage groove at the bottom of the liquid distribution cover can evenly deliver the enzyme preparation to the top of the filter membrane mechanism, thereby avoiding premature clogging of the membrane core in a certain area due to uneven liquid distribution, and further improving the durable processing life of the membrane core. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 This is a schematic diagram of the overall structure of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0030] Figure 2 A schematic diagram of the splitting structure of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0031] Figure 3 A schematic diagram of the lateral splitting structure of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0032] Figure 4 This is a schematic diagram of the split structure of the liquid distribution mechanism of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0033] Figure 5 A schematic diagram of the lateral structure of a liquid distribution mechanism of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0034] Figure 6 A schematic diagram of the assembly structure of a filter membrane control mechanism of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0035] Figure 7 The present invention proposes Figure 6 The structural diagram of the enlarged part A in the middle;

[0036] Figure 8 This is a schematic diagram of the lateral split structure of the liquid distribution mechanism of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0037] Fig. 9 A schematic diagram of the structure of a liquid seat from a top view of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0038] Fig.10 This is a schematic diagram of the split structure of the filter membrane mechanism of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0039] Fig.11 This is a schematic diagram of the split structure of the filter membrane control mechanism of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention;

[0040] Fig.12 This is a schematic diagram of the lateral structure of the filter membrane control mechanism of a sterile filtration device for earthworm fibrinolytic enzyme proposed by the present invention.

[0041] Legend:

[0042] 1. Filtration kettle; 2. Kettle cover; 3. Filter membrane mechanism; 301. Upper membrane layer; 302. Membrane core; 303. Lower membrane layer; 4. Filter membrane control mechanism; 401. Rotating disk; 402. Expanding disk; 403. Card slot; 404. Track slot; 405. Elastic cover; 406. Extrusion block; 407. Drive ring; 5. Liquid distribution mechanism; 501. Liquid distribution cover; 502. Liquid drainage groove; 503. Liquid distribution cover; 504. Moving ring; 505. Push cylinder; 506. Shielding cover; 507. Liquid introduction roller; 508. Closing ring; 509. Liquid seat; 510. Guide rod; 511. Blocking block; 512. First spring; 6. Extrusion rod; 7. Force block; 8. Drive shaft; 9. Flushing valve pipe; 10. Liquid drainage port. DETAILED DESCRIPTION

[0043] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0044] See also Figure 1-Figure 12 The present invention provides a technical solution: a sterile filtration device for earthworm fibrinolytic enzyme, comprising a filtration kettle 1, a kettle cover 2 is provided on the top of the filtration kettle 1, and a liquid inlet pipe is provided on the top of the kettle cover 2, a liquid discharge port 10 is connected to the bottom of the filtration kettle 1, a plurality of filter membrane mechanisms 3 are arranged in an array through the inner cavity of the filtration kettle 1, and the enzyme preparation is sterile filtered through the filter membrane mechanisms 3 in sequence, a filter membrane control mechanism 4 is provided in the inner cavity of the filter membrane mechanism 3, and the filter membrane control mechanism 4 drives the filter membrane mechanism 3 to expand the membrane layer spacing, and two sets of flushing valve pipes 9 are provided on the outer wall of the filtration kettle 1, and the flushing valve pipe 9 is connected to the external backwashing pump body;

[0045] A liquid distribution mechanism 5 is provided on the top of the filtration kettle 1. The liquid distribution mechanism 5 is located on the top of the filter membrane mechanism 3. The liquid distribution mechanism 5 is connected to the liquid inlet of the top kettle cover 2 to control the aseptic injection of the enzyme preparation.

[0046] There are multiple support legs on the two sides of the kettle cover, and reinforcing ribs are provided at the bottom of the support legs;

[0047] Specifically: the designed filter membrane mechanism 3 can filter the earthworm fibrinolytic enzyme preparation, i.e., the enzyme preparation, in sequence, and can drive the filter membrane mechanism 3 to expand the membrane layer spacing through the filter membrane control mechanism 4 to perform lateral flushing, thereby reducing the accumulation of impurities in the filter membrane mechanism 3, which is beneficial to improving the durability of the filter membrane mechanism 3 through backwashing, and through the set liquid distribution mechanism 5, the enzyme preparation to be filtered can be evenly arranged on the top of the filter membrane mechanism 3, which is beneficial to improving the filtering effect.

[0048] See also Figure 1 , Fig.11 and Fig.12 The filter membrane mechanism 3 includes an upper membrane layer 301 and a lower membrane layer 303, and a plurality of membrane cores 302 are equidistantly arranged around the upper membrane layer 301 and the lower membrane layer 303 along the axis, and the inner side of the membrane core 302 is connected to one side of the filter membrane control mechanism 4 at the corresponding position, and the membrane core 302 is unfolded by pulling the membrane control mechanism 4 to unfold;

[0049] The membrane control mechanism 4 includes a plurality of rotating disks 401 and unfolding disks 402 corresponding to each other. A plurality of extrusion blocks 406 are connected to the rotating disk 401 at one side of the unfolding disk 402 at equal distances along the axis. A plurality of track grooves 404 corresponding to the extrusion blocks 406 are opened at equal distances along the axis on the unfolding disk 402 at one side of the rotating disk 401. The rotation of the rotating disk 401 drives the extrusion blocks 406 to rotate in the track grooves 404, drives the unfolding disk 402 to move, and pulls the membrane core 302 to unfold.

[0050] The outer sides of the rotating disk 401 and the unfolding disk 402 are rotatably connected with elastic covers 405, and the two sides of the elastic covers 405 are respectively connected to the two sides of the membrane core 302, and the space between the rotating disk 401 and the unfolding disk 402 is closed by the elastic covers 405;

[0051] In addition, a plurality of rotating disks 401 are provided with a slot 403 in the inner cavity, a driving ring 407 is clamped in the slot 403, a driving shaft 8 is rotatably connected between the plurality of driving rings 407, and the driving shaft 8 is rotatably connected to the bottom side of the inner cavity of the filter kettle 1, and the rotation of the rotating disk 401 is controlled by the rotation of the driving shaft 8.

[0052] Specifically: after the enzyme preparation is injected into the liquid distributing mechanism 5 through the cover top feed port, the liquid distributing mechanism 5 can evenly distribute the enzyme preparation solution on the top of the filter membrane structure, and after filtering through multiple upper membrane layers 301, membrane core 302 and lower membrane layer 303 in sequence, the enzyme preparation can be discharged through the bottom liquid discharge port 10. When it is necessary to rinse the membrane core 302, the driving shaft 8 can be used to drive the driving ring 407 and the rotating disk 401 to rotate, and the rotation of the rotating disk 401 can be driven on the track through the bottom extrusion block 406. The extrusion block 406 rotates in the groove 404 and can rotate to contact the arc surface of the inner cavity of the track groove 404 to squeeze the unfolding disk 402 away from the rotating disk 401 on the corresponding side. At this time, the multiple movable rotating disks 401 can be unfolded by the elastic cover 405 and pull the inner membrane core 302 to unfold, so that the contact range with the lateral flushing liquid can be increased through the unfolded membrane core 302, which is conducive to fully flushing the blocked membrane core 302, and the durability is extended through the flushable filter membrane mechanism 3, the maintenance frequency is reduced, and the use effect is improved;

[0053] Through the designed filter membrane mechanism 3, under the cooperation of the reset driving shaft 8, the elastic contraction of the elastic cover 405 is used to control the contraction of the membrane core 302, and the filtration of the enzyme preparation is continued, which is conducive to filtering the enzyme preparation through the shrinkable and controllable membrane core 302, and avoids the accumulation of enzyme preparation due to the expansion of the gap, which affects the filtration effect;

[0054] See also Figure 4-Figure 7 , both sides of the inner cavity of the top groove of the driving shaft 8 are connected with force blocks 7, the bottom of the liquid distribution mechanism 5 is connected with an electric push rod, the bottom of the electric push rod is connected with an extrusion rod 6, and both sides of the bottom of the extrusion rod 6 are connected with extrusion balls through the rod body, and the force blocks 7 are squeezed by the extrusion balls to rotate the driving shaft 8, and the driving shaft 8 is rotatably connected to the bottom side of the inner cavity of the filter kettle 1 through the rewinding bearing;

[0055] The driving shaft 8 can be driven to rotate by a driving motor, and the driving motor can be arranged at the bottom side of the filter kettle 1 or the bottom side of the liquid distribution mechanism 5;

[0056] At the same time, through the designed driving shaft 8, when the driving shaft 8 is driven to rotate, the top electric push rod can be extended to drive the extrusion rod 6 to move downward, and the movement of the extrusion rod 6 can squeeze the force-bearing block 7 through the bottom extrusion ball, and the force-bearing block 7 can use the top inclined surface to convert the downward force into a rotational driving force to drive the driving shaft 8 to rotate. When the driving shaft 8 rotates, it can pull the bottom side rewinding bearing. Therefore, when the electric push rod is reset, the rewinding bearing can pull the driving shaft 8 to reset, so that the driving part can be placed on the top of the enzyme preparation, without the need for an additional rotation drive mechanism, thereby improving the rotation stability of the driving shaft 8 and reducing the pollution to the enzyme preparation;

[0057] The slot 403 in the inner cavity of the rotating disk 401 can be engaged with the driving ring 407 at the corresponding position to facilitate the rotation drive;

[0058] See also Figure 4-Figure 9 The liquid distributing mechanism 5 comprises a liquid distributing cover 501, a plurality of liquid draining grooves 502 are arranged around the bottom of the liquid distributing cover 501 at equal intervals along the axis, a liquid distributing cover 503 is arranged in the inner cavity of the liquid distributing cover 501, the liquid distributing cover 503 comprises a plurality of spiral liquid guiding plates arranged obliquely, and a moving ring 504 is slidably connected to the top of the liquid distributing cover 501, a liquid seat 509 is installed on both sides of the top of the moving ring 504 through a pushing cylinder 505, and a shielding cover 506 is connected between the liquid seat 509 and the moving ring 504, and the top chamber of the liquid seat 509 is connected to the bottom side of the kettle cover 2;

[0059] The inner cavity of the liquid seat 509 is slidably connected with a closed ring 508, and the bottom of the closed ring 508 is equidistantly connected with a plurality of blocking blocks 511 around the axis. The bottom of the liquid seat 509 is provided with leakage holes at positions corresponding to the blocking blocks 511, and a closed seat is provided in the leakage hole, and the blocking blocks 511 are sealed and embedded in the closed seat;

[0060] The cross-sectional shape of the inner cavity of the sealing seat is conical, and the cross-sectional shape of the blocking block 511 is conical, and the leakage gap is opened by moving the blocking block 511 upward and separating from the sealing seat;

[0061] A receiving groove is provided in the inner cavity of the movable ring 504 at a position corresponding to the liquid seat 509. A plurality of liquid introduction rollers 507 are equidistantly connected to the inner cavity of the receiving groove through the plate body along the axis. A through groove is provided at the bottom of the inner cavity of the receiving groove at a position corresponding to the liquid introduction roller 507. The liquid introduction roller 507 corresponds to the bottom of the blocking block 511. The movable ring 504 moves to drive the liquid introduction roller 507 to push the blocking block 511 to separate from the closing seat.

[0062] Guide holes are provided on both sides of the bottom of the closed ring 508, and guide rods 510 are slidably connected in the guide holes, and the guide rods 510 are connected to the bottom of the inner cavity of the liquid seat 509. The outer wall of the guide rods 510 is sleeved with a first spring 512, and the two ends of the first spring 512 are respectively connected to the corresponding positions of the liquid seat 509 and one side of the closed ring 508;

[0063] Specifically, when the enzyme preparation is filtered, when liquid needs to be fed, the liquid inlet pipe on the top of the kettle cover 2 can be used to transport the enzyme preparation into the liquid seat 509 through the external pump body. When the enzyme preparation at the bottom is filtered in the filter membrane structure, the cylinder 505 can be controlled to shorten and pull the moving ring 504 to move. The movement of the moving ring 504 can drive the inner liquid introduction roller 507 to move upward. The upward movement of the liquid introduction roller 507 can push the blocking block 511 to separate from the closed seat and open the leakage gap, so that the blocking block 511 can be driven to close the liquid seat 509 through the sliding of the closed ring 508, which is conducive to quickly controlling the feeding of the enzyme preparation to the filter membrane mechanism 3, facilitating the feeding control during filtration, facilitating the adjustment of the filtration waiting time of the enzyme preparation, improving the filtration adaptability, and reducing the contamination of the enzyme preparation in the filtration kettle 1 into the feed pipe, meeting the needs of continuous production, and the multiple liquid outlets arranged in an annular shape at the bottom of the liquid seat 509 can cooperate with the bottom liquid equalizing cover 503 to improve the uniformity of liquid distribution;

[0064] The opened gap can introduce the enzyme preparation into the containing groove and enter the bottom liquid distribution cover 503. The liquid guide plate in the liquid distribution cover 503 can evenly disperse the enzyme preparation into the bottom liquid distribution cover 501 after receiving the enzyme preparation. The drainage groove 502 at the bottom of the liquid distribution cover 501 can evenly deliver the enzyme preparation to the top of the filter membrane mechanism 3, so as to avoid premature clogging of the membrane core 302 in a certain area due to uneven liquid distribution, which affects the overall durability of the filter membrane mechanism 3.

[0065] In the present invention, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance; the term "plurality" refers to two or more, unless otherwise clearly defined. The terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; "connected" can be a direct connection or an indirect connection through an intermediate medium. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0066] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A sterile filtration device for earthworm fibrinolytic enzyme, comprising a filter kettle (1), wherein the top of the filter kettle (1) is provided with a kettle cover (2), and the top of the kettle cover (2) is provided with a liquid inlet pipe, and the bottom of the filter kettle (1) is connected to a liquid discharge port (10), characterized in that: The inner cavity of the filter kettle (1) is provided with a plurality of filter membrane mechanisms (3) arranged in an array, and the enzyme preparation is sterile-filtered through the filter membrane mechanisms (3) in sequence. The inner cavity of the filter membrane mechanism (3) is provided with a filter membrane control mechanism (4), and the filter membrane mechanism (3) is driven by the filter membrane control mechanism (4) to expand the membrane layer spacing. The outer wall of the filter kettle (1) is provided with two sets of flushing valve pipes (9), and the flushing valve pipes (9) are connected to the external backwashing pump body; The top of the filter kettle (1) is provided with a liquid distributing mechanism (5), which is located on the top of the filter membrane mechanism (3) and is connected to the liquid inlet of the top kettle cover (2) through the liquid distributing mechanism (5) to control the aseptic injection of the enzyme preparation; The filter membrane mechanism (3) comprises an upper membrane layer (301) and a lower membrane layer (303), and a plurality of membrane cores (302) are equidistantly arranged around the upper membrane layer (301) and the lower membrane layer (303) along the axis, and the inner side of the membrane core (302) is connected to one side of the filter membrane control mechanism (4) at a corresponding position, and the membrane core (302) is unfolded by pulling the membrane control mechanism (4) to unfold; The membrane control mechanism (4) includes a plurality of rotating disks (401) and unfolding disks (402) corresponding to each other, wherein the rotating disks (401) and the unfolding disks (402) are rotatably connected to the outer sides thereof with elastic covers (405), and the two sides of the elastic covers (405) are respectively connected to the upper membrane layer (301) and the lower membrane layer (303) at corresponding positions, and the space between the rotating disk (401) and the unfolding disk (402) is closed by the elastic covers (405), and a plurality of extrusion blocks (406) are connected to the side of the rotating disk (401) corresponding to the unfolding disk (402) at equal intervals along the axis, and a plurality of track grooves (404) corresponding to the extrusion blocks (406) are opened to the side of the unfolding disk (402) corresponding to the rotating disk (401) at equal intervals along the axis, and the rotation of the rotating disk (401) drives the extrusion blocks (406) to rotate in the track grooves (404), thereby driving the unfolding disk (402) to move and pull the membrane core (302) to unfold; The liquid distribution mechanism (5) includes a liquid distribution cover (501), a plurality of liquid drainage grooves (502) are equidistantly arranged around the bottom of the liquid distribution cover (501) along the axis, a liquid distribution cover (503) is provided in the inner cavity of the liquid distribution cover (501), the liquid distribution cover (503) includes a plurality of spiral liquid guide plates arranged obliquely, and a moving ring (504) is slidably connected to the top of the liquid distribution cover (501), a liquid seat (509) is installed on both sides of the top of the moving ring (504) through a pushing cylinder (505), and a shielding cover (506) is connected between the liquid seat (509) and the moving ring (504), and the top chamber of the liquid seat (509) is connected to the bottom side of the kettle cover (2); The inner cavity of the liquid seat (509) is slidably connected to a closed ring (508), and the bottom of the closed ring (508) is equidistantly connected to a plurality of blocking blocks (511) along the axis. The bottom of the liquid seat (509) is provided with leakage holes at positions corresponding to the blocking blocks (511), and a closed seat is provided in the leakage hole. The blocking blocks (511) are sealed and embedded in the closed seat.

2. The sterile filtration device for earthworm fibrinolytic enzyme according to claim 1, characterized in that: The inner cavities of the plurality of rotating disks (401) are each provided with a slot (403), a driving ring (407) is clamped in the slot (403), a driving shaft (8) is rotatably connected between the plurality of driving rings (407), and the driving shaft (8) is rotatably connected to the bottom side of the inner cavity of the filter kettle (1), and the rotation of the rotating disk (401) is controlled by the rotation of the driving shaft (8).

3. The sterile filtration device for earthworm fibrinolytic enzyme according to claim 2, characterized in that: Both sides of the inner cavity of the top groove of the driving shaft (8) are connected to force blocks (7), the bottom of the liquid distribution mechanism (5) is connected to an electric push rod, the bottom of the electric push rod is connected to an extrusion rod (6), and both sides of the bottom of the extrusion rod (6) are connected to extrusion balls through the rod body, and the force blocks (7) are squeezed by the extrusion balls to rotate the driving shaft (8), and the driving shaft (8) is rotatably connected to the bottom side of the inner cavity of the filter kettle (1) through the rewinding bearing.

4. The sterile filtration device for earthworm fibrinolytic enzyme according to claim 1, characterized in that: The cross-sectional shape of the inner cavity of the closing seat is conical, and the cross-sectional shape of the blocking block (511) is also conical, and the leakage gap is opened by the blocking block (511) moving upward and separating from the closing seat.

5. The sterile filtration equipment for earthworm fibrinolytic enzyme according to claim 1, characterized in that: The inner cavity of the movable ring (504) is provided with a receiving groove at a position corresponding to the liquid seat (509), and the inner cavity of the receiving groove is connected to a plurality of liquid introduction rollers (507) at equal intervals along the axis through the plate body. A through groove is provided at the bottom of the inner cavity of the receiving groove at a position corresponding to the liquid introduction roller (507), and the liquid introduction roller (507) corresponds to the bottom of the blocking block (511). The movable ring (504) moves to drive the liquid introduction roller (507) to push the blocking block (511) to separate from the closing seat.

6. The sterile filtration equipment for earthworm fibrinolytic enzyme according to claim 5, characterized in that: Guide holes are provided on both sides of the bottom of the closed ring (508), and guide rods (510) are slidably connected in the guide holes. The guide rods (510) are connected to the bottom of the inner cavity of the liquid seat (509). A first spring (512) is sleeved on the outer wall of the guide rod (510), and the two ends of the first spring (512) are respectively connected to corresponding positions on one side of the liquid seat (509) and the closed ring (508).

Images