Hydrogel visual identification detection device and detection method

Abstract

The application discloses a hydrogel visual identification detection equipment and a detection method, wherein the detection equipment comprises a rack, a light source module, a camera module, a mask and an observation box connected to the rack; the observation box comprises a detection grid for storing hydrogel and a test solution. The detection equipment adopts the camera module to shoot the hydrogel to realize observation and recording of the swelling condition of the hydrogel, and is more convenient to operate, more accurate in detection result and higher in detection efficiency. During detection, the light source module, the mask, the observation box and the camera module are sequentially distributed along the vertical direction, the light source module irradiates towards the mask, the light transmits through the mask and irradiates into the observation box, and the mask provides a distinct contrast color for the hydrogel, so that the hydrogel can be visually identified, the problem that the hydrogel cannot be visually detected due to high transparency is solved, the hydrogel shot by the camera module is clearer and more complete, and the swelling performance of the hydrogel is better analyzed.

Description

Technical Field

[0001] This invention relates to the field of hydrogel performance testing technology, specifically to a hydrogel visual recognition testing device and testing method. Background Technology

[0002] The swelling property of hydrogels refers to their ability to absorb a large amount of water from a solution, resulting in an increase in volume without dissolving. Theoretically, the swelling property of hydrogels can be detected by observing and recording changes in volume or by weighing them. However, due to the extremely high water content and transparency of hydrogels, their outer contours are difficult to observe and visually identify, and the edges are difficult to accurately segment. Therefore, direct observation of volume changes is impractical. Currently, commonly used methods involve indirectly recording volume or weight changes, such as the tea bag method, sieve method, filtration method, weighing method, and fluorescence method. However, the tea bag, sieve, and filtration methods limit the contact between the hydrogel and the test solution, preventing sufficient contact and restricting expansion and deformation, leading to inaccurate swelling rates. The weighing method requires precise weighing and operation, and is easily affected by external factors, reducing the accuracy of the results. Fluorescence methods are also susceptible to interference from fluorescence signals and background noise, which can reduce the accuracy of detection results. Furthermore, these methods generally require complex detection equipment or high technical skills, are relatively cumbersome to operate, and are easily affected by experimental conditions, resulting in low detection efficiency and large errors in the detection results. Summary of the Invention

[0003] To overcome the shortcomings of the prior art, the present invention aims to provide a hydrogel visual recognition and detection device that can solve the problem that visual detection is impossible due to the high transparency of hydrogels. It can detect the swelling property of hydrogels by directly observing and recording the volume changes of hydrogels, thereby improving detection efficiency and accuracy of detection results.

[0004] To solve the above problems, the technical solution adopted by the present invention is as follows: a hydrogel visual recognition and detection device, comprising a frame and a light source module, a camera module, a mask, and an observation box connected to the frame; the mask is located between the light source module and the camera module; the observation box includes a detection grid for storing hydrogel and test solution; during detection, the light source module, the mask, the observation box, and the camera module are arranged sequentially in a vertical direction, the light source module irradiates towards the mask, and the camera module continuously captures images of the hydrogel in the detection grid.

[0005] Compared to existing technologies, the advantages of this invention are as follows: This detection device uses a camera module to photograph the hydrogel to observe and record its swelling. This is a direct and intuitive method for observing and recording changes in hydrogel volume, eliminating the need for sieves or filters. Therefore, it does not restrict the contact between the hydrogel and the test solution, nor does it limit the expansion and deformation of the hydrogel itself. Consequently, the detection results are more accurate, the detection efficiency is higher, and the operation is more convenient. During detection, the device arranges the light source module, mask, observation box, and camera module vertically. The light source module illuminates the mask, allowing light to pass through and enter the observation box. The mask provides a clear contrast color to the hydrogel, enabling visual identification and solving the problem of visual detection being impossible due to the high transparency of the hydrogel. This results in clearer and more complete images of the hydrogel captured by the camera module, allowing for accurate segmentation of the hydrogel's edge contours for observation and recording of its swelling, and better analysis of its swelling properties.

[0006] In the aforementioned hydrogel visual recognition and detection device, the observation box is further provided with a first communication port and a second communication port that are interconnected with the detection grid. The first communication port is used to add test solution into the detection grid, and the second communication port is used to drain the test solution from the detection grid.

[0007] The aforementioned hydrogel visual recognition and detection device further includes a moving module and a flipping module connected to the frame. The flipping module is connected to the output end of the moving module and can move vertically relative to the frame under the drive of the moving module. The observation box is connected to the output end of the flipping module and can flip relative to the frame under the drive of the flipping module.

[0008] In the aforementioned hydrogel visual recognition and detection device, the first connecting port is connected to a first pipe, which is connected to a liquid inlet pipe and an air inlet pipe via a two-way pipe; the second connecting port is connected to a second pipe, which is connected to a drain pipe and an exhaust pipe via a two-way pipe; during liquid inlet, the flipping module drives the observation box to flip so that the first connecting port faces downwards and the second connecting port faces upwards, opening the liquid inlet pipe and the exhaust pipe, and closing the air inlet pipe and the drain pipe. The test solution enters the detection cell through the first connecting port, and the air in the detection cell enters through the second connecting port. After the liquid is discharged, the inlet pipe and the outlet pipe are closed. The flipping module drives the observation box to flip so that the observation box is flat. The moving module drives the flipping module and the observation box to move vertically so that the observation box is placed flat between the mask and the camera module. During the liquid discharge, the flipping module drives the observation box to flip so that the first connecting port faces upward and the second connecting port faces downward. The drain pipe and the air inlet pipe are opened to fill the detection cell with air from the first connecting port so that the test solution in the detection cell is discharged through the second connecting port.

[0009] In the aforementioned hydrogel visual recognition and detection equipment, the moving module can drive the flipping module to move horizontally and / or vertically relative to the frame.

[0010] The above-mentioned hydrogel visual recognition and detection device has multiple detection grids, each of which can store multiple hydrogels of the same composition, and multiple detection grids can store hydrogels of different compositions.

[0011] The aforementioned hydrogel visual recognition and detection device includes an observation box comprising a box body and a cover plate. The detection grid is disposed within the box body, and the cover plate seals and closes to the side of the box body to seal the detection grid. An installation cavity is provided within the box body, and a first connecting port and a second connecting port are respectively located at opposite ends of the box body and communicate with the installation cavity. A grid frame is installed within the box body, and the detection grid is distributed on the grid frame. A gap exists between the outer periphery of the grid frame and the inner periphery of the installation cavity to form a liquid channel, and the liquid channel communicates with the detection grid.

[0012] In the aforementioned hydrogel visual recognition and detection equipment, the light source module and / or the camera module can move horizontally and / or vertically relative to the frame.

[0013] In the aforementioned hydrogel visual recognition and detection device, the height of the grid frame is lower than the height of the mounting cavity, so that the liquid channel and the detection grid are interconnected.

[0014] The aforementioned hydrogel visual recognition and detection device has multiple light-transmitting and non-light-transmitting areas distributed on the mask.

[0015] The present invention also provides a method for visual recognition and detection of hydrogels, which uses the above-mentioned visual recognition and detection equipment for detection and includes the following steps:

[0016] Step S100: Place the hydrogel into the detection cell and add the test solution into the detection cell;

[0017] Step S200: Place the observation box flat between the mask and the camera module, turn on the light source module and the camera module, so that the light source module shines towards the mask, and the camera module takes pictures of the hydrogel in the observation box to obtain a set of time-series image data.

[0018] Step S300: Process the image data to obtain the size data of the hydrogel in each image;

[0019] Step S400: Plot the fitting curve of the hydrogel size data over time to evaluate the swelling property of the hydrogel.

[0020] This detection method uses the aforementioned hydrogel visual recognition detection equipment for detection, and it has at least all the beneficial effects that the aforementioned hydrogel visual recognition detection equipment can bring. In addition, this detection method can continuously take pictures of the hydrogel through the camera module, and obtain the fitting curve of the hydrogel size data over time through data processing, so as to evaluate the swelling property of the hydrogel.

[0021] The present invention will now be described in further detail with reference to the accompanying drawings and specific embodiments. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the overall structure of the detection device according to an embodiment of the present invention;

[0023] Figure 2 This is a schematic diagram of the structure of the light source module and the camera module according to an embodiment of the present invention;

[0024] Figure 3 This is a schematic diagram of the structure of the mobile module according to an embodiment of the present invention;

[0025] Figure 4 This is a schematic diagram of the structure of the flip module and observation box according to an embodiment of the present invention;

[0026] Figure 5 This is a schematic diagram of the observation box according to an embodiment of the present invention;

[0027] Figure 6 for Figure 5 Sectional view of AA;

[0028] Figure 7This is a schematic diagram of the mask structure according to an embodiment of the present invention;

[0029] Figure 8 , Figure 9 and Figure 10 These are image data of the nine hydrogels in Example 2 at three different time points with large intervals;

[0030] Figure 11 These are the swelling curves of the nine hydrogels in Example 2 of this invention;

[0031] Figure 12 This is an image taken without a mask in Embodiment 3 of the present invention;

[0032] Figure 13 The image is taken with a mask in Embodiment 3 of the present invention.

[0033] Explanation of icon numbers:

[0034] 100 rack, 110 first vertical guide rail, 120 fixed base;

[0035] 200 Light source module, 210 First slider, 220 Planar light source;

[0036] 300 camera module, 310 second slider, 320 horizontal slide rail, 330 third slider, 340 industrial camera;

[0037] 400 mask, 410 transparent area, 420 non-transparent area;

[0038] 500 Observation box, 510 Box body, 511 First connecting port, 512 Second connecting port, 513 Liquid channel, 514 Annular groove, 520 Grid frame, 521 Detection grid, 530 Pose sensor;

[0039] 600 Moving module, 610 Second vertical guide rail, 620 Fourth slider, 630 Driving component;

[0040] 700 flip module, 710 rotary motor. Detailed Implementation

[0041] The embodiments of the present invention are described in detail below:

[0042] Example 1

[0043] Reference Figures 1 to 7Embodiment 1 of the present invention provides a hydrogel visual recognition and detection device, including a frame 100 and a light source module 200, a camera module 300, a mask 400 and an observation box 500 connected to the frame 100; the mask 400 is located between the light source module 200 and the camera module 300; the observation box 500 includes a detection grid 521 for storing hydrogel and test solution; during detection, the light source module 200, the mask 400, the observation box 500 and the camera module 300 are arranged in sequence along the vertical direction, the light source module 200 irradiates towards the mask 400, and the camera module 300 continuously photographs the hydrogel in the detection grid 521.

[0044] It should be noted that the light source module 200, camera module 300, mask 400, and observation box 500 can be directly connected to the frame 100, or indirectly connected to the frame 100 through other structures. The mask 400 can be directly connected to the light source module 200 or directly connected to the frame 100, as long as it is located between the light source module 200 and the camera module 300. The light source module 200, mask 400, observation box 500, and camera module 300 can be arranged sequentially from top to bottom or from bottom to top, as long as the order of arrangement is met. The specific structures of the camera module 300 and the light source module 200 are not the focus of this application. For example, the camera module 300 can be a commonly used industrial camera 340, as long as it can achieve continuous shooting; the light source module 200 can be a planar light source 220, as long as it can illuminate towards the mask 400. Their specific structures will not be described in detail here.

[0045] Compared to existing technologies, this testing equipment can use a camera module 300 to photograph the hydrogel to observe and record its swelling. This is a direct and intuitive way to observe and record changes in the volume of the hydrogel. It does not require the use of sieves or filters, so it does not restrict the contact between the hydrogel and the test solution, nor does it restrict the expansion and deformation of the hydrogel itself. Therefore, the test results are more accurate, the testing efficiency is higher, and the operation is more convenient. During testing, this testing equipment arranges the light source module 200, mask 400, observation box 500, and camera module 300 vertically. The light source module 200 illuminates the mask 400, allowing light to pass through the mask 400 and into the observation box 500. The mask 400 provides a distinct contrast color to the hydrogel, enabling visual recognition of the hydrogel. This solves the problem of visual inspection being impossible due to the high transparency of the hydrogel. The camera module 300 captures clearer and more complete images of the hydrogel, allowing for accurate segmentation of the hydrogel's edge contours. This facilitates observation and recording of the hydrogel's swelling and better analysis of its swelling properties.

[0046] Furthermore, in some embodiments, the observation box 500 can be removed from the rack 100, filled with the observed substance and sealed, and then reinstalled onto the rack 100 for recording. (Refer to...) Figure 5 and Figure 6 In some other embodiments, two connecting ports, a first port 511 and a second port 512, can be provided in the observation box 500 to communicate with the detection cell 521. The first port 511 is used to add the test solution into the detection cell 521, and the second port 512 is used to drain the test solution from the detection cell 521. When it is necessary to test the swelling property of the hydrogel, the test solution can be added into the detection cell 521 through the first port 511, and after the test is completed, the test solution in the detection cell 521 can be drained through the second port 512.

[0047] Furthermore, this testing equipment also includes a moving module 600 and a flipping module 700 connected to the frame 100. The flipping module 700 is connected to the output end of the moving module 600 and can move horizontally and / or vertically relative to the frame 100 under the action of the moving module 600. The observation box 500 is connected to the output end of the flipping module 700 and can flip relative to the frame 100 under the action of the flipping module 700. The moving module 600 can move the flipping module 700 and the observation box 500, so that the observation box 500 is located between the mask 400 and the camera module 300, so that the camera module 300 can photograph the hydrogel inside the observation box 500. The flipping module 700 can flip the observation box 500 to facilitate the addition or removal of the test solution.

[0048] Furthermore, the first connecting port 511 is sealed and connected to a first pipeline, which is connected to a liquid inlet pipe and an air inlet pipe via a two-way pipe. Valves are installed on both the liquid inlet pipe and the air inlet pipe to facilitate opening or closing them. The second connecting port 512 is sealed and connected to a second pipeline, which is connected to a drain pipe and an exhaust pipe via a two-way pipe. Similarly, valves are installed on both the drain pipe and the exhaust pipe to facilitate opening or closing them. In this invention, the first pipeline, the two-way pipe, the liquid inlet pipe, the air inlet pipe, the valves, the second pipeline, the drain pipe, the exhaust pipe, the test solution supply device, and the waste liquid collection device connected to the drain pipe are all structurally similar and their connections and functions are readily apparent from the textual description. These structures are also commonly used in the field and are therefore not shown in the accompanying drawings.

[0049] During liquid injection, the moving module 600 can move the flipping module 700 away from the camera module 300 and the light source module 200 to prevent the flipping of the observation box 500 from being affected by the mask 400 or the camera module 300. Then, the flipping module 700 flips the observation box 500 so that the first connecting port 511 faces downwards and the second connecting port 512 faces upwards, opening the liquid inlet pipe and the exhaust pipe, and closing the air inlet pipe and the liquid outlet pipe. Since the lower air inlet pipe is closed, the hydraulic pump connected to the liquid inlet pipe can be turned on to force the test solution into the detection cell 521 through the first connecting port 511. Since the upper drain pipe is closed, as the test solution is gradually added into the detection cell 521, the air inside the detection cell 521 will be discharged through the second connecting port 512 and the exhaust pipe. The flipping module 700 of this testing device can rotate the observation box 500, so that the first connecting port 511 faces downward. This allows for a bottom-up liquid injection method, ensuring that the air inside the observation box 500 is completely expelled and that the observation box 500 is completely filled with the test solution. This ensures that the hydrogel in the detection grid 521 can fully contact the test solution, thereby improving the accuracy of the test results.

[0050] After the liquid filling is completed, the inlet pipe and the exhaust pipe are closed. The flip module 700 rotates the observation box 500 90° to flatten it. Since the air inlet pipe, the drain pipe, the liquid inlet pipe, and the exhaust pipe are all closed at this time, the observation box 500 is in a completely sealed state. Therefore, even when the observation box 500 is flattened, the test solution inside will not be discharged through the first connecting port 511 or the second connecting port 512. Of course, in some embodiments, more test solution can be added so that both the first and second pipes are filled with test solution, thereby ensuring that the observation box 500 remains full of test solution when it is flattened.

[0051] During testing, the moving module 600 moves the flipping module 700 and the observation box 500 so that the observation box 500 is placed flat between the mask 400 and the camera module 300. The relative positions of the light source module 200, the observation box 500, and the camera module 300 are adjusted to find a clearer image for capture. To precisely find a clear image, the moving module 600 can drive the flipping module 700 to move horizontally, vertically, or both. Similarly, the light source module 200 can move horizontally or vertically relative to the frame 100, or both. The camera module 300 can also move horizontally or vertically relative to the frame 100, or both. The mask 400 can also move horizontally or vertically relative to the frame 100, or both. This allows for better adjustment of the relative positions of the light source module 200, mask 400, observation box 500, and camera module 300, enabling the search for clearer images, the acquisition of clearer image data, and ultimately, the improvement of the accuracy of the detection results.

[0052] After the test is completed, when drainage is required, the flip module 700 drives the observation box 500 to flip so that the first connecting port 511 faces upward and the second connecting port 512 faces downward. The lower drain pipe and the upper air inlet pipe are opened to fill the test cell 521 with air from the first connecting port 511, so that the test solution in the test cell 521 is discharged through the second connecting port 512. Since the deformation of the hydrogel is reversible, when the test solution in the test cell 521 is completely discharged and after a period of time, the hydrogel deformation is restored. At this time, the next test solution can be filled for testing.

[0053] In this application, horizontal or vertical movement can be achieved by means of cylinder drive or motor screw drive, and rotation can be achieved by means of rotary motor. For example, see reference Figure 1 and Figure 2 The frame 100 is equipped with a first vertical guide rail 110. The light source module 200 is connected to the first vertical guide rail 110 via a first slider 210. Driving the first slider 210 via a cylinder or similar structure allows the light source module 200 to move vertically. The camera module 300 is connected to the first vertical guide rail 110 via a second slider 310. Driving the second slider 310 via a cylinder or similar structure allows the camera module 300 to move vertically. A horizontal slide rail 320 is also connected to the second slider 310. The industrial camera 340 is connected to the horizontal slide rail 320 via a third slider 330. Driving the third slider 330 via a cylinder or similar structure allows the industrial camera 340 to move horizontally. (Refer to...) Figure 1 and Figure 3The moving module 600 includes a second vertical guide rail 610 mounted on the frame 100, a fourth slider 620 connected to the second vertical guide rail 610, and a driving member 630 that drives the fourth slider 620 to move vertically. The flipping module 700 is connected to the fourth slider 620. When the driving member 630 drives the fourth slider 620 to move vertically, it can drive the flipping module 700 to move vertically. Alternatively, a horizontal driving member can be connected to the fourth slider 620, and the flipping module 700 can be connected to the output end of the horizontal driving member, so that the flipping module 700 can move horizontally on the fourth slider 620.

[0054] Furthermore, continue to refer to Figure 3 The frame 100 includes a mounting plate. A first vertical guide rail 110 and a second vertical guide rail 610 are both connected to the mounting plate. A fixed base 120 can be provided at the bottom of the first vertical guide rail 110 and the second vertical guide rail 610, and the fixed base 120 is fixed to the mounting plate using bolts or other threaded fasteners. Multiple bolt holes can be provided on the mounting plate to facilitate adjustment of the mounting positions of the first vertical guide rail 110 and the second vertical guide rail 610. To improve the stability of the flip module 700 during vertical movement, two sets of the second vertical guide rail 610 can be arranged side-by-side. Further, refer to... Figure 4 The flipping module 700 includes a rotary motor 710 connected to the fourth slider 620, and an observation box 500 connected to the output end of the rotary motor 710. When the rotary motor 710 is started, it can drive the observation box 500 to flip. A pose sensor 530 is also connected to the observation box 500 to facilitate the identification and detection of the position status of the observation box 500.

[0055] Furthermore, referring to Figures 4 to 6 Multiple detection grids 521 are spaced apart, and each grid 521 can hold multiple hydrogels of the same component. Of course, space needs to be reserved within each grid 521 for the hydrogels to deform. In this embodiment, the hydrogels are spherical; therefore, the hydrogels are not in complete contact with each other, nor with the inner wall of the grid 521, thus not affecting their deformation. Placing multiple hydrogels of the same component within one grid 521 ensures that at least one complete hydrogel image can be found. If more than one complete hydrogel image exists in the field of view, the average value can be taken, further reducing detection error. Multiple detection grids 521 can hold hydrogels of different components, allowing detection of which component of the hydrogel has the best swelling properties under the same test solution. By sequentially introducing different test solutions, the hydrogel component with the best swelling properties, as well as the solution composition and concentration, can be identified.

[0056] Furthermore, continue to refer to Figures 4 to 6The observation box 500 includes a box body 510 and a cover plate. A detection grid 521 is located inside the box body 510. The cover plate seals the side of the box body 510 to seal the detection grid 521. An annular groove 514 is formed on the box body 510, and a sealing ring is pressed into the annular groove 514. After the hydrogel is placed, the cover plate is placed on the side of the box body 510 and locked with bolts or other threaded connectors. The sealing ring then seals the side of the box body 510. The cover plate is not shown in the attached drawings, but it can be understood as a plate that seals the box body 510. This plate can be made of transparent acrylic. Furthermore, an installation cavity is provided inside the box body 510. A first connecting port 511 and a second connecting port 512 are respectively located at opposite ends of the box body 510 and communicate with the installation cavity. A grid frame 520 is installed inside the box body 510, and detection grids 521 are distributed on the grid frame 520 to achieve separation between multiple detection grids 521. In this embodiment, the grid frame 520 is in a nine-square grid pattern, which can effectively expand the range of visual inspection, allowing for the simultaneous detection of the swelling properties of nine types of hydrogels, further improving detection efficiency. Furthermore, a gap exists between the outer periphery of the grid frame 520 and the inner periphery of the installation cavity to form a liquid channel 513. The liquid channel 513 communicates with the detection grids 521, allowing the test solution entering from the first connecting port 511 to enter each detection grid 521 through the liquid channel 513. Specifically, as... Figure 6 As shown, the height of the grid frame 520 can be set lower than the height of the mounting cavity, so that there is a gap between the top of the grid frame 520 and the cover plate, and the test solution in the liquid channel 513 can enter each detection cell 521 through the gap.

[0057] Furthermore, referring to Figure 7 The mask 400 has multiple spaced-apart light-transmitting areas 410 and light-blocking areas 420. The light-transmitting areas 410 allow light to pass through, while the light-blocking areas 420 add background color, thereby making the image captured by the camera module 300 clearer. Specifically, a black and white film can be used to form the required mask 400.

[0058] Example 2

[0059] Embodiment 2 of the present invention provides a hydrogel visual recognition and detection method, which uses the above-mentioned hydrogel visual recognition and detection equipment for detection and includes the following steps:

[0060] Step S100: Place the hydrogel into the detection cell 521 and add the test solution into the detection cell 521;

[0061] Step S200: Place the observation box 500 flat between the mask 400 and the camera module 300, turn on the light source module 200 and the camera module 300, so that the light source module 200 shines in the direction of the mask 400, and the camera module 300 takes pictures of the hydrogel inside the observation box 500, thereby obtaining a set of image data with time series.

[0062] Step S300: Process the image data to obtain the size data of the hydrogel in each image;

[0063] Step S400: Plot the fitting curve of the hydrogel size data over time to evaluate the swelling property of the hydrogel.

[0064] This detection method utilizes the aforementioned hydrogel visual recognition detection equipment, possessing at least all the beneficial effects offered by such equipment. Furthermore, this method continuously photographs the hydrogel using the camera module 300 and processes the data to obtain a fitting curve of the hydrogel's size data over time, facilitating the evaluation of its swelling properties. For example, based on the image data, the radius can be selected as an evaluation parameter for the hydrogel's volume change. One time point corresponds to one radius data point, and multiple time points correspond to multiple radius data points. By using the time points as the x-axis and the radius data as the y-axis, multiple points can be recorded on the coordinate system. Fitting these points to a curve yields the hydrogel's swelling curve, allowing for the calculation of the swelling rate and evaluation of its swelling performance.

[0065] For example, refer to Figures 8 to 10 This example provides image data of nine hydrogels at three different time points with relatively large intervals in a 0.15 mg / ml solution (solute: glucose, solvent: PBS). In practice, there can be more time points for detection. (Refer to...) Figure 11 This embodiment provides swelling curves for nine hydrogels in a specific test solution. It can be seen that, for the same test solution, the swelling properties of hydrogels with different components vary. Based on these swelling curves, the group with the best swelling performance among these nine hydrogels can be identified. Furthermore, it can be observed approximately how long it takes for each component hydrogel to reach a stable state.

[0066] Example 3

[0067] Reference Figure 12 and Figure 13 , Figure 12 and Figure 13 These are comparative images taken using the same camera module 300 on the same hydrogel within the same observation box 500. The difference lies in... Figure 12 These images were taken without a mask at 400mm. Figure 13 These images were taken with a 400mm mask. (See reference.) Figure 12 As can be seen, when directly photographing hydrogels using the camera module 300, the highly transparent hydrogels are extremely susceptible to reflection and refraction during image acquisition. Although the outline edges of some hydrogel components are visible, almost half of the hydrogels have unclear outline edges, making it impossible to record the swelling of the hydrogels. (Refer to...) Figure 13 As can be seen, when taking pictures with the mask 400, the outlines of multiple hydrogels are clearly visible in all detection grids 521, which proves that this detection device has successfully solved the problem of visual detection being impossible due to the high transparency of hydrogels.

[0068] It should be noted that in the description of this invention, any descriptions of orientation, such as up, down, front, back, left, right, etc., indicating orientation or positional relationships, are based on the orientation or positional relationships shown in the accompanying drawings. They are only for the purpose of facilitating the description of this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed or operated in a specific orientation, and should not be construed as a limitation of this invention.

[0069] In the description of this invention, "several" means one or more, "more than" means two or more, "greater than," "less than," "exceeding," etc. are understood to exclude the stated number, while "above," "below," "within," etc. are understood to include the stated number. If "first" or "second" is mentioned, it is only for the purpose of distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.

[0070] In the description of this invention, unless otherwise explicitly defined, terms such as "set up," "install," and "connect" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this invention in conjunction with the specific content of the technical solution.

[0071] The above embodiments are merely preferred embodiments of the present invention and should not be construed as limiting the scope of protection of the present invention. Any non-substantial changes and substitutions made by those skilled in the art based on the present invention shall fall within the scope of protection claimed by the present invention.

Claims

1. A hydrogel visual recognition and detection device, characterized in that, It includes a frame (100) and a light source module (200), a camera module (300), a mask (400) and an observation box (500) connected to the frame (100); The mask (400) is located between the light source module (200) and the camera module (300); The observation box (500) includes a detection compartment (521) for storing hydrogel and test solution. The observation box (500) also has a first connection port (511) and a second connection port (512) that are interconnected with the detection compartment (521). The first connection port (511) is used to add test solution into the detection compartment (521), and the second connection port (512) is used to discharge the test solution in the detection compartment (521). The first connection port (511) is connected to a first pipeline, which is connected to an inlet pipe and an air inlet pipe through a two-way pipe. The second connection port (512) is connected to a second pipeline, which is connected to an outlet pipe and an exhaust pipe through a two-way pipe. It also includes a movable module (600) and a flip module (700) connected to the frame (100). The flip module (700) is connected to the output end of the movable module (600) and can move relative to the frame (100) under the drive of the movable module (600). The observation box (500) is connected to the output end of the flip module (700) and can flip relative to the frame (100) under the drive of the flip module (700). When liquid is introduced, the flipping module (700) drives the observation box (500) to flip so that the first connecting port (511) faces down and the second connecting port (512) faces up, opening the liquid inlet pipe and the exhaust pipe, and closing the air inlet pipe and the liquid outlet pipe. The test solution enters the detection cell (521) through the first connecting port (511), and the air in the detection cell (521) is discharged through the second connecting port (512). After the liquid inlet is completed, the liquid inlet pipe and the exhaust pipe are closed. The flipping module (700) drives the observation box (500) to flip so that the observation box (500) is flat. The moving module (600) drives the flipping module (700) and the observation box (500) to move so that the observation box (500) is placed flat between the mask (400) and the camera module (300). During drainage, the flipping module (700) drives the observation box (500) to flip so that the first connecting port (511) faces upward and the second connecting port (512) faces downward. The drainage pipe and the air inlet pipe are opened, and air is filled into the detection cell (521) from the first connecting port (511) so that the test solution in the detection cell (521) is discharged through the second connecting port (512). During testing, the light source module (200), the mask (400), the observation box (500), and the camera module (300) are arranged in sequence along the vertical direction. The light source module (200) illuminates the mask (400), and the camera module (300) continuously captures images of the hydrogel in the detection grid (521).

2. The hydrogel visual recognition and detection device according to claim 1, characterized in that, The moving module (600) can drive the flipping module (700) to move horizontally and / or vertically relative to the frame (100).

3. The hydrogel visual recognition and detection device according to claim 1, characterized in that, The detection cells (521) are spaced in multiples, and each detection cell (521) can store multiple hydrogels of the same composition, while multiple detection cells (521) can store hydrogels of different compositions.

4. The hydrogel visual recognition and detection device according to claim 3, characterized in that, The observation box (500) includes a box body (510) and a cover plate. The detection grid (521) is located inside the box body (510). The cover plate seals and covers the side of the box body (510) to seal the detection grid (521). The box body (510) has an installation cavity, and the first communication port (511) and the second communication port (512) are respectively opened at opposite ends of the box body (510) and communicate with the installation cavity; A grid frame (520) is installed inside the box (510), and the detection grids (521) are distributed on the grid frame (520). There is a gap between the outer periphery of the grid frame (520) and the inner periphery of the mounting cavity to form a liquid channel (513). The liquid channel (513) is in communication with the detection grids (521).

5. The hydrogel visual recognition and detection device according to claim 1, characterized in that, The light source module (200) and / or the camera module (300) may move horizontally and / or vertically relative to the frame (100).

6. The hydrogel visual recognition and detection device according to claim 1, characterized in that, The mask (400) has a plurality of light-transmitting areas (410) and non-light-transmitting areas (420) arranged at intervals.

7. A method for visual recognition and detection of hydrogels, characterized in that, The detection using the hydrogel visual recognition and detection device as described in any one of claims 1-6 includes the following steps: Step S100: Place the hydrogel into the detection cell (521) and add the test solution into the detection cell (521); Step S200: Place the observation box (500) flat between the mask (400) and the camera module (300), turn on the light source module (200) and the camera module (300), so that the light source module (200) shines towards the mask (400), and the camera module (300) takes pictures of the hydrogel in the observation box (500) to obtain a set of image data with time series. Step S300: Process the image data to obtain the size data of the hydrogel in each image; Step S400: Plot the fitting curve of the hydrogel size data over time to evaluate the swelling property of the hydrogel.

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