Bicomponent heterostructured absorbable monofilament and method of spinning same

Abstract

The application relates to a two-component heteromorphic structure partially absorbable monofilament and a spinning method thereof, and relates to the field of medical partially absorbable monofilaments. The spinning method provided by the application adopts a melt spinning process to prepare a two-component heteromorphic structure partially absorbable monofilament, which comprises a skeleton structure part in a cross section in the shape of a rice character and a main body structure part. The skeleton structure part is a bioabsorbable material, and the main body structure part is a non-bioabsorbable material. In this case, the two-component heteromorphic structure partially absorbable monofilament prepared by the application is applied to implants such as sutures used in medical operations, so that the safety and success rate of surgical treatment can be improved, tissue repair and regeneration can be promoted, and the development and innovation of the medical device field are also promoted. The application has a profound influence on promoting the development of the medical and health industry.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of partially absorbable monofilaments for medical use, in particular to a partially absorbable monofilament with a bicomponent heterostructure and a spinning method thereof. BACKGROUND

[0002] With the continuous progress of medical technology, the requirements for materials are also becoming higher and higher, and it is necessary to have multiple characteristics such as biocompatibility, mechanical properties and absorbability. Therefore, through the research and development of partially absorbable monofilaments, new breakthroughs and progress can be brought to the field of medical devices, expanding treatment methods and methods.

[0003] In the prior art, the implants such as sutures used in medical operations are usually non-absorbable, and need to be removed by secondary surgery or permanently left in the body, which can easily cause risks such as infection, foreign body reaction and tissue damage.

[0004] With the development of biomedical engineering, partially absorbable monofilaments have become a new type of substitute, aiming to improve the recovery process after surgery and reduce unnecessary complications. Commonly used bioabsorbable materials include polylactic acid (PLA), polyglycolide (PGA), polycaprolactone (PCL) and the like. These materials have good bioabsorbable properties and can gradually decompose into harmless substances such as carbon dioxide and water in the body. Partially absorbable monofilaments have a positive impact on tissue repair and regeneration, and compared with traditional non-degradable materials, the absorbable monofilaments are closer to the structure and properties of natural tissues, which is beneficial to the growth, repair and regeneration of tissues. This has important significance for fracture treatment, soft tissue repair and the like, and can promote the rapid recovery of patients. Overall, the research and development of partially absorbable monofilaments for medical use can not only improve the safety and success rate of surgical treatment and promote tissue repair and regeneration, but also contribute to the development and innovation of the field of medical devices, and has a profound impact on the development of the medical and health industry. SUMMARY

[0005] The purpose of the present application is to provide a partially absorbable monofilament with a bicomponent heterostructure and a spinning method thereof, in order to solve the technical problem that the implants such as sutures used in existing medical operations are usually non-absorbable, need to be removed by secondary surgery or permanently left in the body, and can easily cause risks such as infection, foreign body reaction and tissue damage.

[0006] To achieve the above-mentioned purpose, the technical solution adopted by the present application is as follows:

[0007] In a first aspect, the present application provides a partially absorbable monofilament with a bicomponent heterostructure, comprising:

[0008] a skeleton structure part, the cross section of which is in the shape of a rice character, and which is a bioabsorbable material; and

[0009] The main structure part is a bioabsorbable material.

[0010] In a possible implementation, the bioabsorbable material at least includes one of polycaprolactone, polylactic acid, polyglycolide, poly-p-dioxanone, and polyglycolide-polycaprolactone copolymer.

[0011] In a possible implementation, the bioabsorbable material at least includes one of polypropylene, polyethylene, and polyamide.

[0012] In a second aspect, the application provides a spinning method of a two-component heterostructure partially absorbable monofilament, which is suitable for a melt spinning device, and the melt spinning device includes two sets of feeding ports, two sets of spiral extrusion mechanisms, two sets of metering pumps, a two-component rice-shaped spinning mechanism, a godet, a slow cooling-drawing mechanism, a drying mechanism, and a winding mechanism in sequence according to a process route.

[0013] The method includes the following steps.

[0014] S1, the bioabsorbable material and the bioabsorbable material are pre-dried, the drying temperature is 80-90℃, the drying time is 24 hours, and the dried bioabsorbable material and the dried bioabsorbable material are obtained.

[0015] S2, the dried bioabsorbable material and the dried bioabsorbable material are poured into two sets of the feeding ports respectively, and are extruded through two sets of the spiral extrusion mechanisms corresponding to the two sets of the feeding ports, to obtain the extruded bioabsorbable material and the extruded bioabsorbable material.

[0016] S3, the extruded bioabsorbable material and the extruded bioabsorbable material are respectively conveyed to two sets of the metering pumps corresponding to two sets of the spiral extrusion mechanisms, to control the proportion of the extruded bioabsorbable material and the extruded bioabsorbable material, and to obtain the metered bioabsorbable material and the metered bioabsorbable material.

[0017] S4, the metered bioabsorbable material and the metered bioabsorbable material are conveyed to the two-component rice-shaped spinning mechanism, to obtain the formed monofilament.

[0018] S5, the formed monofilament is introduced into the slow cooling-drawing mechanism through the godet for slow cooling and drawing, is dried through the drying mechanism, and is finally wound by the winding mechanism, to obtain the two-component heterostructure partially absorbable monofilament.

[0019] In a possible implementation, in the step S1,

[0020] The melting point temperature difference between the bioabsorbable material and the non-bioabsorbable material is less than or equal to 30 DEG C.

[0021] In a possible implementation, in the step S2:

[0022] The temperature parameters of the spiral extrusion mechanism include at least a flange temperature, a zone 1 temperature, a zone 2 temperature, a zone 3 temperature, and a box temperature.

[0023] In a possible implementation, in the step S3:

[0024] The ratio of the extruded bioabsorbable material to the extruded non-bioabsorbable material ranges from 3:7 to 6:4.

[0025] In a possible implementation, in the step S4:

[0026] The double-component Y-shaped spinning mechanism includes, from top to bottom, a flow guiding layer, a flow dividing layer, a shaping layer, and a filament forming layer.

[0027] The flow guiding layer has two inner circle holes for guiding the metered non-bioabsorbable material and two outer circle holes for guiding the metered bioabsorbable material.

[0028] The flow dividing layer has eight inner circle holes for dividing the metered non-bioabsorbable material and ten outer circle holes for dividing the metered bioabsorbable material.

[0029] The shaping layer has a circular inner six-hole for flowing in the metered non-bioabsorbable material, forming a main structure part of a single filament.

[0030] The shaping layer further has a cylindrical inner hole for flowing in the metered bioabsorbable material, forming a skeleton structure part of the single filament.

[0031] The filament forming layer is used for spinning out the shaped single filament.

[0032] In a possible implementation, in the step S5:

[0033] The slow cooling and drawing mechanism includes a water slow cooling part and a combined drawing roller part, and is used for slow cooling and drawing the shaped single filament.

[0034] The technical scheme provided by the present application has at least the following beneficial effects:

[0035] The spinning method provided by the application adopts a melt spinning process to prepare a double-component heteromorphic structure partially absorbable monofilament, which comprises a skeleton structure part in a cross-section in the shape of a rice character and a main body structure part, the skeleton structure part is a bioabsorbable material, and the main body structure part is a non-bioabsorbable material. In this case, the double-component heteromorphic structure partially absorbable monofilament prepared by the application is applied to an implant such as a suture used in a medical operation, which can improve the safety and success rate of surgical treatment, promote tissue repair and regeneration, and also help the development and innovation of the medical device field, and has a profound impact on promoting the development of the medical and health industry. BRIEF DESCRIPTION OF DRAWINGS

[0036] The accompanying drawings are included to provide a further understanding of the application, and constitute a part of the specification, illustrate the application, and are used to explain the application together with the embodiments of the application, and do not constitute a limitation on the application. In the drawings:

[0037] Figure 1 A cross-sectional structure schematic diagram of a double-component heteromorphic structure partially absorbable monofilament provided by an example embodiment of the application is shown;

[0038] Figure 2 A flowchart schematic diagram of a spinning method of a double-component heteromorphic structure partially absorbable monofilament provided by an example embodiment of the application is shown;

[0039] Figure 3 A structure schematic diagram of a melt spinning device provided by an example embodiment of the application is shown;

[0040] Figure 4 A structure schematic diagram of a double-component rice character type spinning mechanism of a melt spinning device provided by an example embodiment of the application is shown;

[0041] Figure 5 An X-ray diffraction test result diagram of a polyglycolide-poly-caprolactone copolymer provided by an example embodiment of the application is shown;

[0042] Figure 6 An X-ray diffraction test result diagram of a polypropylene provided by an example embodiment of the application is shown;

[0043] Figure 7 An infrared spectrum diagram of a double-component heteromorphic structure partially absorbable monofilament provided by an example embodiment of the application is shown;

[0044] Figure 8 A strength test result diagram of a double-component heteromorphic structure partially absorbable monofilament provided by an example embodiment of the application is shown;

[0045] Figure 9Fig. 1 shows a mechanical property test result diagram of a bi-component profiled structure absorbable monofilament provided by an example embodiment of the present application;

[0046] Figure 10 Fig. 2 shows an in-vitro degradation test result diagram of a bi-component profiled structure absorbable monofilament provided by an example embodiment of the present application. DETAILED DESCRIPTION

[0047] The technical solutions in the embodiments of the present application will be apparently and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by a person of ordinary skill in the art without creative work fall within the scope of protection of the present application.

[0048] In the description, the terms "front", "back", "left", "right", "top" and "bottom" refer to the directions in the drawings of the present application, and the terms "bottom surface" and "top surface", "inner" and "outer" refer to the directions towards or away from a specific part. In addition, the terms "first" and "second" are used only for the purpose of description, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined with "first" and "second" can explicitly or implicitly include one or more features. In the description of the present application, the meaning of "multiple" is two or more.

[0049] The present application will be further described below with reference to the drawings and embodiments.

[0050] Figure 1 Fig. 1 shows a mechanical property test result diagram of a bi-component profiled structure absorbable monofilament provided by an example embodiment of the present application;

[0051] Figure 2 Fig. 1 shows a mechanical property test result diagram of a bi-component profiled structure absorbable monofilament provided by an example embodiment of the present application; Figure 3The melt spinning device comprises two groups of feeding ports 21, two groups of spiral extrusion mechanisms 22, two groups of metering pumps 23, a double-component rice-shaped spinning mechanism 24, a godet 25, a slow cooling-drawing mechanism 26, a drying mechanism 27, and a winding mechanism 28 in sequence according to a process route.

[0052] The method specifically comprises the following steps:

[0053] In step S1, the bioabsorbable material and the non-bioabsorbable material are pre-dried at a drying temperature of 80-90 DEG C for 24 hours to obtain dried bioabsorbable material and dried non-bioabsorbable material.

[0054] In the embodiment, the melting point temperature difference between the bioabsorbable material and the non-bioabsorbable material is less than or equal to 30 DEG C.

[0055] In step S2, the dried bioabsorbable material and the dried non-bioabsorbable material are respectively poured into two groups of feeding ports 21 and extruded by two groups of spiral extrusion mechanisms 22 corresponding to the two groups of feeding ports 21 to obtain extruded bioabsorbable material and extruded non-bioabsorbable material.

[0056] In the embodiment, the temperature parameters of the spiral extrusion mechanism 2 include at least a flange temperature, a first zone temperature, a second zone temperature, a third zone temperature, and a box temperature.

[0057] In step S3, the extruded bioabsorbable material and the extruded non-bioabsorbable material are respectively conveyed to two groups of metering pumps 23 corresponding to the two groups of spiral extrusion mechanisms 22 to control the ratio of the extruded bioabsorbable material and the extruded non-bioabsorbable material, and obtain metered bioabsorbable material and metered non-bioabsorbable material.

[0058] Optionally, the ratio of the extruded bioabsorbable material and the extruded non-bioabsorbable material ranges from 3:7 to 6:4.

[0059] In step S4, the metered bioabsorbable material and the metered non-bioabsorbable material are conveyed to the double-component rice-shaped spinning mechanism 24 to obtain a formed single filament.

[0060] In the embodiment, please refer to Figure 4As shown in the figure, the two-component rice-shaped spinning mechanism 4 includes, from top to bottom, a flow guiding layer 241, a flow dividing layer 242, a shaping layer 243, and a filament forming layer 244; the flow guiding layer 241 has two inner circle holes for guiding the flow of the metered bioabsorbable material and two outer circle holes for guiding the flow of the metered bioabsorbable material; the flow dividing layer 242 has eight inner circle holes for dividing the flow of the metered bioabsorbable material and ten outer circle holes for dividing the flow of the metered bioabsorbable material; the shaping layer 243 has a circular inner six-hole for flowing in the metered bioabsorbable material, forming a main body structure part of the single filament; the shaping layer 243 also has a cylindrical inner hole for flowing in the metered bioabsorbable material, forming a skeleton structure part of the single filament; and the filament forming layer 244 is used for spinning out the shaped single filament.

[0061] Step S5: The shaped single filament is guided into the slow cooling-drawing mechanism 26 by the godet 25 to be slowly cooled and drawn, dried by the drying mechanism 27, and finally wound by the winding mechanism 28 to obtain the two-component heteromorphic structure absorbable single filament.

[0062] In the embodiment, the slow cooling-drawing mechanism 6 includes a water slow cooling part and a combined drawing roller part, which are used for slowly cooling and drawing the shaped single filament, and the drawing multiple or drawing rate of the single filament can be set as needed. In addition, the godet 25 plays a role in controlling the running direction of the single filament.

[0063] In order to better understand the present application, the present application will be further described below in combination with the accompanying drawings and a specific embodiment. It should be noted that the specific embodiment described in the specific embodiment is only a part of the embodiments of the present application, and does not limit the scope of protection of the present application.

[0064] The spinning method of the two-component heteromorphic structure absorbable single filament provided in the embodiment adopts a melt spinning method, and the method is suitable for a melt spinning device. Please combine the description of the melt spinning device with the description of the spinning method. Figure 3 As shown in the figure, the melt spinning device includes, in sequence according to the process route, two sets of feeding ports 21, two sets of spiral extrusion mechanisms 22, two sets of metering pumps 23, a two-component rice-shaped spinning mechanism 24, a godet 25, a slow cooling-drawing mechanism 26, a drying mechanism 27, and a winding mechanism 28.

[0065] The above method specifically includes the following steps:

[0066] Step S1: The bioabsorbable material (optionally, polyglycolide-poly-caprolactone copolymer injection molding particles, melting point 190°C) and the bioabsorbable material (optionally, polypropylene injection molding particles, melting point 160°C) are pre-dried, the drying temperature is 85°C, and the drying time is 24 hours to obtain the dried bioabsorbable material (polyglycolide-poly-caprolactone copolymer injection molding particles) and the dried bioabsorbable material (polypropylene injection molding particles).

[0067] Step S2: The dried bioabsorbable material (polyglycolic acid-polycaprolactone copolymer injection granules) and the dried non-bioabsorbable material (polypropylene injection granules) are poured into two sets of feed ports 21 respectively, and extruded through two sets of screw extrusion mechanisms 22 corresponding to the two sets of feed ports 21 to obtain extruded bioabsorbable material (polyglycolic acid-polycaprolactone copolymer injection granules) and extruded non-bioabsorbable material (polypropylene injection granules).

[0068] In step S2, the temperature parameters of the screw extrusion mechanism 2 include at least the flange temperature, zone one temperature, zone two temperature, zone three temperature, and chamber temperature. Specifically, the flange temperature of the poly(lactic-co-caprolactone) copolymer injection molding granules is 240℃, the zone one temperature is 220℃, the zone two temperature is 230℃, the zone three temperature is 235℃, and the chamber temperature is 240℃; the flange temperature of the polypropylene injection molding granules is 260℃, the zone one temperature is 260℃, the zone two temperature is 265℃, the zone three temperature is 270℃, and the chamber temperature is 268℃.

[0069] Step S3: The extruded bioabsorbable material (polyglycolic acid-polycaprolactone copolymer injection granules) and the extruded non-bioabsorbable material (polypropylene injection granules) are respectively fed into the two sets of metering pumps 23 corresponding to the two sets of screw extrusion mechanisms 22. This is used to control the ratio of the extruded bioabsorbable material to the extruded non-bioabsorbable material, so as to obtain metered bioabsorbable material (polyglycolic acid-polycaprolactone copolymer injection granules) and metered non-bioabsorbable material (polypropylene injection granules).

[0070] In step S3, the melt ratio of the poly(glycolic acid-polycaprolactone) copolymer injection granules is 60%, and the melt ratio of the polypropylene injection granules is 40%.

[0071] In step S3, the metering pump temperature of the poly(glycolic acid)-poly(caprolactone) copolymer injection granules is 245°C, the hot box temperature is 235°C, and the anti-drying temperature is 240°C; the metering pump temperature of the polypropylene injection granules is 260°C, the hot box temperature is 90°C, and the anti-drying temperature is 100°C.

[0072] Step S4: The metered bioabsorbable material (polyglycolic acid-polycaprolactone copolymer injection granules) and the metered non-absorbable material (polypropylene injection granules) are fed into the two-component star-shaped spinneret 24 to obtain the formed monofilament.

[0073] In step S4, please combine Figure 4The bicomponent star-shaped spinneret 4 includes, from top to bottom, a flow-guiding layer 241, a flow-diverting layer 242, a forming layer 243, and a filament-forming layer 244. The flow-guiding layer 241 has two inner holes for guiding metered non-absorbable biomaterial and two outer holes for guiding metered bioabsorbable biomaterial. The flow-diverting layer 242 has eight inner holes for diverting metered non-absorbable biomaterial and ten outer holes for diverting metered bioabsorbable biomaterial. The forming layer 243 has six circular inner holes for the inflow of metered non-absorbable biomaterial, forming the main structure of the monofilament. The forming layer 243 also has cylindrical inner holes for the inflow of metered bioabsorbable biomaterial, forming the skeleton structure of the monofilament. The filament-forming layer 244 is used to eject the formed monofilament.

[0074] In step S4, the component pressure of the two-component cross-shaped spinneret 24 is 16 MPa, and the post-filtration pressure is 8 MPa.

[0075] Step S5: The formed monofilament is guided through the guide roller 25 into the slow cooling-drawing mechanism 26 for slow cooling and drawing, then dried by the drying mechanism 27, and finally wound up by the winding mechanism 28 to obtain a bicomponent asymmetrical absorbable monofilament.

[0076] Performance testing:

[0077] The obtained bicomponent heterostructure absorbable monofilaments were subjected to basic characterization, mechanical property and in vitro degradation performance tests.

[0078] like Figure 1 As shown, the cross-sectional structure of the absorbable monofilament in the bicomponent asymmetrical structure exhibits a star-shaped pattern. The framework structure 11 is a bioabsorbable material, poly(glycolic acid)-polycaprolactone copolymer, and its X-ray diffraction test results are as follows... Figure 5 As shown. The main structural part 12 is made of non-bioabsorbable polypropylene, and its X-ray test results are as follows. Figure 6 As shown. The infrared spectrum of the absorbable monofilament in the bicomponent heterostructure is shown below. Figure 7 As shown in the figure, the partial absorbable monofilament phase composition is composed of poly(glycolic acid)-polycaprolactone copolymer and polypropylene, consistent with the raw material. The two components did not undergo a chemical reaction during melt spinning, but only physically bonded, indicating that the two components can play different roles in subsequent applications.

[0079] The bicomponent profiled section can absorb the mechanical properties of monofilaments, such as... Figure 8 and Figure 9 As shown, its tensile breaking strength reaches 59.9 cN / dtex, which meets the application requirements of medical sutures and other similar products.

[0080] In vitro degradation test results of some absorbable monofilaments are as follows: Figure 10As shown in the results, when the degradation medium is PBS, the degradation mass of the monofilament reaches 15% after 15 days, and the degradation mass of the monofilament reaches 42% after 30 days. When the degradation medium is NaOH, the degradation rate of the monofilament is increased, and when the concentration of NaOH is 2.5%, the absorbable part of the monofilament can be completely degraded in about 15 days.

[0081] In summary, the present application provides a spinning method for preparing a biocompatible monofilament with a double-component heteromorphic structure by using a melt spinning process. The monofilament includes a skeleton structure part with a cross-section in the shape of a rice character and a main structure part. The skeleton structure part is a bioabsorbable material, and the main structure part is a non-bioabsorbable material. In this case, the biocompatible monofilament with a double-component heteromorphic structure prepared by the present application can be applied to implants such as sutures used in medical operations, which can improve the safety and success rate of surgical treatment, promote tissue repair and regeneration, and also contribute to the development and innovation of the medical device field, and has a profound impact on the development of the medical and health industry.

[0082] The above only describes the preferred embodiments of the present application, and it should be pointed out that those skilled in the art can make several improvements and refinements without departing from the principles of the present application, and these improvements and refinements should also be considered as the protection scope of the present application.

Claims

1. A method of spinning a bi-component, hetero-structured, partially absorbable monofilament, characterized in that, The method is suitable for a melt spinning device, which sequentially includes two groups of feeding ports, two groups of spiral extrusion mechanisms, two groups of metering pumps, a double-component rice-shaped spinning mechanism, a godet, a slow cooling-drawing mechanism, a drying mechanism, and a winding mechanism in a process route; The method comprises: S1, pre-drying bioabsorbable material and non-bioabsorbable material, drying temperature 80-90℃, drying time 24 hours, to obtain dried bioabsorbable material and dried non-bioabsorbable material; S2, pouring the dried bioabsorbable material and the dried non-bioabsorbable material into two groups of feeding ports respectively, and extruding the dried bioabsorbable material and the dried non-bioabsorbable material through two groups of spiral extrusion mechanisms corresponding to the two groups of feeding ports, to obtain extruded bioabsorbable material and extruded non-bioabsorbable material; S3, conveying the extruded bioabsorbable material and the extruded non-bioabsorbable material to two groups of metering pumps corresponding to two groups of spiral extrusion mechanisms respectively, to control the ratio of the extruded bioabsorbable material and the extruded non-bioabsorbable material, to obtain metered bioabsorbable material and metered non-bioabsorbable material; S4, conveying the metered bioabsorbable material and the metered non-bioabsorbable material to the double-component rice-shaped spinning mechanism, to obtain formed monofilaments; The double-component rice-shaped spinning mechanism comprises, from top to bottom, a flow guiding layer, a flow dividing layer, a forming layer, and a filament forming layer; The flow guiding layer has two holes in the inner circle for guiding the metered non-bioabsorbable material, and two holes in the outer circle for guiding the metered bioabsorbable material; The flow dividing layer has eight holes in the inner circle for dividing the metered non-bioabsorbable material, and ten holes in the outer circle for dividing the metered bioabsorbable material; The forming layer has a circular inner six-hole for flowing in the metered non-bioabsorbable material, to form a main structure part of the monofilament; The forming layer also has a cylindrical inner hole for flowing in the metered bioabsorbable material, to form a skeleton structure part of the monofilament; The filament forming layer is used for spraying the formed monofilaments out S5, guiding the formed monofilaments into the slow cooling-drawing mechanism through the godet for slow cooling and drawing, drying through the drying mechanism, and finally winding by the winding mechanism, to obtain double-component heteromorphic structure partially absorbable monofilaments.

2. The method of spinning bicomponent shaped absorbable monofilaments according to claim 1, wherein In the step S1: The melting point temperature difference between the bioabsorbable material and the non-bioabsorbable material is less than or equal to 30℃.

3. The method of spinning bicomponent shaped absorbable monofilaments according to claim 1, wherein In the step S2: The temperature parameters of the spiral extrusion mechanism include at least flange temperature, one-zone temperature, two-zone temperature, three-zone temperature, and box temperature.

4. The method of spinning bicomponent shaped absorbable monofilaments according to claim 1, wherein In the step S3: The ratio of the extruded bioabsorbable material and the extruded non-bioabsorbable material ranges from 3:7 to 6:

4.

5. The method of spinning bicomponent shaped absorbable monofilaments according to claim 1 wherein, In the step S5: The slow cooling-drawing mechanism comprises a water cooling part and a combined drawing roller part, for slow cooling and then drawing the formed monofilaments.

6. The bi-component absorbable monofilament of any one of claims 1 to 5, wherein the bi- component absorbable monofilament is prepared by the bi-component absorbable monofilament spinning method according to claim 6, characterized in that, It comprises: a skeleton structure part, which is in the shape of a rice character in cross section and is bioabsorbable material; and a The main structure part is a bioabsorbable material.

7. The bi-component absorbable monofilament of claim 6, wherein the sheath is formed of a polyglycolic acid and the core is formed of a polydioxanone. The bioabsorbable material at least includes one of polycaprolactone, polylactic acid, polyglycolide, poly-p-dioxanone, polyglycolide-polycaprolactone copolymer.

8. The bi-component absorbable monofilament of claim 6, wherein the sheath is formed of a polyglycolic acid and the core is formed of a polydioxanone. The bioabsorbable material at least includes one of polypropylene, polyethylene, polyamide.

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