An adaptive vascular embolic protection device and embolic system

Abstract

The present invention belongs to the field of medical device technology, specifically an adaptive vascular embolic protection device and embolic system. It includes a delivery guide wire; a filter mesh having an open end and a tail end, the filter mesh being sleeved on the delivery guide wire, the open end of the filter mesh facing the proximal end of the delivery guide wire, and being used to filter emboli; an umbrella-shaped frame being sleeved on the delivery guide wire and arranged at the open end of the filter mesh; an adaptive skirt structure having micropores, which surround and wrap around the open and closed ends of the umbrella-shaped frame, and the open end of the filter mesh being wrapped around the outside of the adaptive skirt structure; nano-scale antispasmodic drug spheres, which are filled in the micropores of the adaptive skirt structure. Compared with the existing technology, this adaptive vascular embolic protection device can significantly improve the effect and safety of embolic protection, bringing better treatment experience and prognosis to patients.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical devices, and in particular relates to an adaptive vascular embolism protection device and an embolism system. Background Art

[0002] Carotid artery stenosis is one of the key causes of ischemic stroke, and its incidence is increasing year by year. When carotid artery stenosis is treated with carotid artery stenting, many embolic fragments are generated. These tiny embolic fragments enter the brain with the bloodstream and are very likely to cause a stroke or damage brain nerve function. To reduce the risk of such complications, an embolic protection device is placed distal to the stent insertion site to capture tiny emboli generated during the procedure without affecting the normal flow of fluid in the blood vessels. After the carotid stent is successfully implanted, the embolic protection device, along with the intercepted emboli, is removed from the body through a retrieval catheter.

[0003] Existing filter-based embolic protection devices can be divided into two types based on the filter frame formation method. The first type uses nickel-titanium alloy tubing cut or wire wrapped and shaped to form the filter umbrella support frame. A polymer membrane with uniform pores is coated on the frame, filtering emboli without hindering the passage of intraluminal fluid. The second type of frame structure is woven into an umbrella shape with a uniformly distributed pore size, which can simultaneously filter blood clots and allow the passage of intraluminal fluid.

[0004] However, given the uneven diameter of carotid arteries, it's difficult to ensure that these devices adhere perfectly to the vessels after deployment. This could lead to emboli escaping through the gap between the device and the vessel wall into distal vessels, potentially damaging the patient's brain tissue or neurological function. Furthermore, during surgery, irritation from the device to the carotid artery can easily trigger carotid vasospasm.

[0005] Based on this, the present invention provides an adaptive vascular embolic protection device and embolic system to overcome the above-mentioned defects. Summary of the Invention

[0006] The first object of the present invention is to provide an adaptive vascular embolic protection device, which can significantly improve the effect and safety of embolic protection and bring better treatment experience and prognosis to patients.

[0007] The present invention adopts the following technical solution: an adaptive vascular embolic protection device, comprising:

[0008] Delivery guidewire;

[0009] A filter mesh having an open end and a closed end, wherein the filter mesh is sleeved on the delivery guide wire, with the open end of the filter mesh facing the proximal end of the delivery guide wire, and is used for filtering emboli;

[0010] An umbrella-shaped frame is sleeved on the conveying guide wire and arranged at the open end of the filter mesh;

[0011] An adaptive skirt structure having micropores surrounding and covering the open and closed ends of the umbrella-shaped frame, and the open end of the filter element covering the outside of the adaptive skirt structure;

[0012] Nano-scale antispasmodic drug spheres are filled in the micropores of the adaptive skirt structure;

[0013] Wherein, the umbrella-shaped frame has an expanded state and a contracted state;

[0014] In the expanded state, the opening and closing ends of the umbrella-shaped skeleton are fully opened, the adaptive skirt structure absorbs liquid to expand, and adheres to the target blood vessel wall; and when the adaptive skirt structure expands, the nano-scale antispasmodic drug balls filled in the micropores of the adaptive skirt structure are squeezed and released to dissolve.

[0015] Furthermore, the surface of the delivery guide wire is coated with a lubricating coating.

[0016] Furthermore, a limiting ring is provided on the conveying guide wire and on both sides of the filter mesh and the umbrella-shaped frame, for limiting the movement of the filter mesh and the umbrella-shaped frame on the conveying guide wire.

[0017] Furthermore, the umbrella-shaped frame includes a frame fixing section, a frame transition section and a frame main section connected in sequence from the proximal end to the distal end; when the umbrella-shaped frame is in the expanded state, the radial internal space of the frame fixing section, the frame transition section and the frame main section increases in sequence.

[0018] Furthermore, the adaptive skirt structure is circumferentially arranged along the outer wall of the skeleton main section, covering at least one circle; and the edge of the adaptive skirt structure on the skeleton main section is connected to the proximal surface of the skeleton transition section.

[0019] Furthermore, the filter mesh is an umbrella-shaped filter membrane, and the open end of the umbrella-shaped filter membrane is covered on the outer wall side of the adaptive skirt structure and extends to cover the skeleton transition section.

[0020] Furthermore, a first developing element is provided at the fixed section of the frame of the delivery guide wire, the first developing element is fixedly connected to the fixed section of the frame of the umbrella-shaped frame, and is slidably connected to the delivery guide wire;

[0021] And / or a second developing element is provided at the tail end of the filter mesh of the conveying guide wire, the second developing element is fixedly connected to the tail end of the filter mesh and is slidably connected to the conveying guide wire.

[0022] Furthermore, a third developing element is provided on the outer wall of the skeleton main body segment.

[0023] Furthermore, an elastic tip is provided at the distal end of the delivery guide wire.

[0024] Compared with the prior art, the present invention has the following beneficial effects:

[0025] The adaptive vascular embolic protection device of the present invention has an umbrella-shaped frame, which has two states: expanded and contracted. In the contracted state, the embolic protection device is easy to transport to the designated location; in the expanded state, it can effectively support the open end of the filter mesh, ensuring that the filter mesh fully plays the role of filtering emboli and improving the effect of embolic protection.

[0026] Secondly, an adaptive skirt structure wraps around the open and closed ends of the umbrella-shaped framework. When it encounters fluid, it absorbs and expands, conforming to the target vessel wall. This design significantly enhances the fit between the device and the vessel wall, minimizing the risk of emboli escaping through the gaps, thereby improving the reliability and safety of embolic protection.

[0027] Furthermore, the nanoscale antispasmodic drug spheres, packed within the micropores of the adaptive skirt structure, are squeezed, released, and dissolved when the adaptive skirt expands. This means that during surgery, antispasmodic drugs can be delivered to the blood vessels in a timely and targeted manner, effectively alleviating carotid artery spasms caused by device stimulation and further reducing surgical risks and the likelihood of complications.

[0028] In summary, this adaptive vascular embolic protection device can significantly improve the effectiveness and safety of embolic protection, bringing patients a better treatment experience and prognosis.

[0029] The second object of the present invention is to provide an embolization system, which includes a delivery catheter and the above-mentioned adaptive vascular embolism protection device, wherein a delivery channel is provided in the delivery catheter, and the adaptive vascular embolism protection device is slidably arranged in the delivery channel of the delivery catheter. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0031] Figure 1 Schematic diagram of the structure of an adaptive vascular embolic protection device according to one embodiment of the present invention;

[0032] Figure 2 This is a schematic diagram of the structure of a delivery catheter transporting an embolic protection device to a suitable position in one embodiment of the present invention;

[0033] Figure 3 This is a schematic structural diagram of an umbrella-shaped frame in a fully expanded state according to an embodiment of the present invention;

[0034] Figure 4 This is a schematic diagram of the structure after the delivery catheter is completely withdrawn in one embodiment of the present invention;

[0035] Figure 5 Schematic diagram of the structure of an embolic protection device in different types of blood vessel walls according to an embodiment of the present invention;

[0036] Figure 6 for Figure 5 Schematic diagram of the structure of the embolic protection device after being released at different locations on the vascular wall;

[0037] Figure 7 Schematic diagram of the recovery process of the embolic protection device in one embodiment of the present invention;

[0038] Figure 8 Schematic diagram of the adaptive skirt structure, umbrella-shaped skeleton and nano-scale antispasmodic drug sphere structure in an embolic protection device according to one embodiment of the present invention;

[0039] Figure 9 Schematic diagram of the structure of nano-scale antispasmodic drug spheres in an embolic protection device according to one embodiment of the present invention;

[0040] Wherein: delivery guide wire 1;

[0041] Filter element 2, open end 20, and tail end 21;

[0042] Umbrella-shaped frame 3, opening and closing end 30, frame fixing section 31, frame transition section 32, frame main section 33;

[0043] Adaptive skirt structure 4;

[0044] Nano-scale antispasmodic drug spheres 5, drug layer 50, matrix 51;

[0045] Limiting ring 6;

[0046] A first developing element 70 and a second developing element 71;

[0047] elastic tip 8;

[0048] Delivery catheter 90 , blood vessel wall 91 , and retrieval catheter 92 . DETAILED DESCRIPTION

[0049] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of the present invention.

[0050] The following is combined with Figure 1 To the attached Figure 9 And specific embodiments, the present invention is discussed in detail:

[0051] It should be noted that the "proximal end" in the above description and the following description usually refers to the end of the medical device close to the operator during normal operation, and the "distal end" usually refers to the end of the medical device that first enters the patient's body during normal operation.

[0052] like Figure 1 As shown, the present invention provides an adaptive vascular embolic protection device, which includes:

[0053] Delivery guidewire 1; Specifically, in this embodiment, the delivery guidewire 1 is a slender guidewire, which can be made of a metal material such as stainless steel or shape memory alloy, and the diameter of the delivery guidewire 1 is generally in the range of about 0.3 mm to 0.4 mm; when in use, the delivery guidewire 1 pushes the filter element 2 to the location of the carotid artery stenosis lesion, while the delivery guidewire 1 does not affect the morphology of the blood vessel;

[0054] The filter mesh 2 has an open end 20 and a tail end 21. The filter mesh 2 is sleeved on the delivery guide wire 1, with the open end 20 of the filter mesh 2 facing the proximal end of the delivery guide wire 1, and is used to filter emboli;

[0055] An umbrella-shaped frame 3 is sleeved on the conveying guide wire 1 and is disposed at the open end 20 of the filter mesh 2 to support the open end 20 of the filter mesh 2. The umbrella-shaped frame 3 supports the filter mesh 2 on the same side.

[0056] An adaptive skirt structure 4 having micropores surrounds and covers the opening and closing end 30 of the umbrella-shaped frame 3 , and the opening end 20 of the filter element 2 covers the outside of the adaptive skirt structure 4 ;

[0057] Nano-scale antispasmodic drug spheres 5 are filled in the micropores of the adaptive skirt structure 4;

[0058] The umbrella-shaped frame 3 has an expanded state and a contracted state;

[0059] In the expanded state, the opening and closing ends 30 of the umbrella-shaped skeleton 3 are fully opened, and the adaptive skirt structure 4 absorbs liquid to expand and adheres to the target blood vessel wall; and when the adaptive skirt structure 4 expands, the nano-scale antispasmodic drug balls 5 filled in the micropores of the adaptive skirt structure 4 are squeezed and released to dissolve.

[0060] The adaptive vascular embolic protection device of the present invention is provided with an umbrella-shaped skeleton 3, which has two states: expanded and contracted. In the contracted state, the embolic protection device is conveniently transported to a designated location; in the expanded state, it can effectively support the open end 20 of the filter mesh 2, ensuring that the filter mesh 2 fully plays the role of filtering emboli and improving the effect of embolic protection.

[0061] Secondly, the adaptive skirt structure 4 wraps around the open and closed ends 30 of the umbrella-shaped frame 3. When exposed to fluid, it absorbs and expands, conforming to the target vessel wall. This design significantly enhances the fit between the device and the vessel wall, minimizing the risk of emboli escaping through gaps, thereby improving the reliability and safety of embolic protection. The effective reduction in the axial length of the embolic protection device and the adaptive skirt structure 4 enhance its compliance and adherence to tortuous vessels, avoiding the gaps that can occur in traditional embolic protection devices, allowing small emboli to escape.

[0062] Furthermore, the nanoscale antispasmodic drug spheres 5 filled in the micropores of the adaptive skirt structure 4 are squeezed, released, and dissolved when the adaptive skirt structure 4 expands. This means that during surgery, antispasmodic drugs can be delivered to the blood vessels in a timely and targeted manner, effectively alleviating carotid artery vasospasm caused by device stimulation, further reducing surgical risks and the likelihood of complications.

[0063] In summary, this adaptive vascular embolic protection device can significantly improve the effectiveness and safety of embolic protection, bringing patients a better treatment experience and prognosis.

[0064] Furthermore, the surface of the delivery guide wire 1 is coated with a lubricating coating to reduce the resistance during the pushing process of the delivery guide wire 1. Specifically, the lubricating coating is a polymer lubricating coating. The polymer lubricating coating can be a coating in the prior art. It is not specifically limited in this application and can be designed and selected by those skilled in the art based on actual conditions. Coating the polymer lubricating coating on the surface of the delivery guide wire 1 reduces the difficulty of pushing, allowing the operator to push the guide wire to the target position more easily and accurately, thereby improving the convenience and accuracy of the surgical operation. At the same time, reducing resistance helps to reduce friction and damage to the inner wall of the blood vessel, reducing the risk of vascular complications. In addition, a smooth pushing process can shorten the operation time, reduce the pain and risks of the patient during the operation, and also improve the efficiency and safety of the operation.

[0065] Furthermore, a limiting ring 6 is provided on the delivery guide wire 1 and on both sides of the filter mesh 2 and the umbrella-shaped frame 3 to limit the movement of the filter mesh 2 and the umbrella-shaped frame 3 on the delivery guide wire 1. Specifically, the limiting ring 6 can be made of a metal tube or a polymer material such as polytetrafluoroethylene (PTFE). The limiting ring 6 is fixed to the delivery guide wire 1 by laser welding or glue bonding, etc., to limit the movement of the filter mesh 2 and the umbrella-shaped frame 3 on the delivery guide wire 1, ensuring the stability of the position on the delivery guide wire 1, thereby ensuring that during the operation, the filter mesh 2 and the umbrella-shaped frame 3 can accurately perform their functions, effectively filter emboli and provide stable support, thereby improving the safety and effectiveness of the operation. At the same time, the provision of the limiting ring 6 can also enhance the strength of the distal end of the delivery guide wire 1 to a certain extent, help improve the stability and controllability of the guide wire in pushing the blood vessel, and reduce the occurrence of operational errors or accidents due to insufficient strength of the distal end of the guide wire.

[0066] Furthermore, the umbrella-shaped frame 3 is formed by thermoforming a shape-memory alloy, forming a compressible and releasable ring-shaped structure. Preferably, the umbrella-shaped frame 3 is formed by thermoforming a shape-memory metal such as nickel-titanium alloy. The umbrella-shaped frame 3 comprises a frame fixing section 31, a frame transition section 32, and a frame main section 33, which are sequentially connected from the proximal end to the distal end. The frame transition section 32 includes multiple frame support rods distributed along the circumference of the umbrella-shaped frame 3, while the frame main section 33 includes multiple wavy connecting rods, each of which is connected to a frame support rod.

[0067] When the umbrella-shaped frame 3 is deployed, the radial interior spaces of the frame fixing section 31, the frame transition section 32, and the frame main section 33 increase sequentially from the proximal end to the distal end. This helps improve the efficiency of thrombus filtration and also makes the umbrella-shaped frame 3 more stable when deployed. Furthermore, after the delivery catheter is removed from the appropriate position, the umbrella-shaped frame 3 self-expands, providing better support and wall adhesion for the filter element 2.

[0068] Specifically, the adaptive skirt structure 4 is a key component that ensures the embolic protection device adheres well to the wall. It is constructed from a highly adaptive, self-expanding, and compressible porous polymer material, such as porous TPU. The adaptive skirt structure 4 circumferentially surrounds the outer wall of the main frame segment 33, providing at least one full circle of protection and sealing. This wraparound design effectively captures potentially escaping emboli at any angle within the vessel, enhancing the reliability of embolic protection. The edge of the adaptive skirt structure 4 on the main frame segment 33 is connected to the proximal surface of the transition segment 32, providing a more coherent and stable structure. This connection enhances the integrity of the structure, prevents potential local separation or displacement during use, and ensures the stability of the embolic protection device within the vessel. In addition, a soft adaptive skirt structure 4 is wrapped around the outer wall of the main frame section 33. Since the skirt structure is closely connected to the frame part, they can work together more effectively when the device is deployed and working, ensuring that the adaptive skirt structure 4 quickly and fully expands and fits the blood vessel wall, thereby improving the efficiency of intercepting emboli. In this embodiment, Figure 8 As shown, the adaptive skirt structure 4 is arranged between the umbrella-shaped frame 3 and the filter mesh element 2, and is fixed to the umbrella-shaped frame 3 by gluing or hot melting.

[0069] Specifically, the filter element 2 is an umbrella-shaped filter membrane, constructed from a single-piece polymer material, such as TPU or PA. The membrane is uniformly perforated using a laser or other process, resulting in pores approximately 100 to 150 microns in diameter. This allows for the capture of emboli without disrupting the flow of fluid within the cavity. The open end 20 of the umbrella-shaped filter membrane wraps around the outer wall of the adaptive skirt structure 4 and extends over the skeleton transition section 32, creating a multi-layered protection system that increases the level of embolic interception, improves the success rate of embolic interception, and reduces the risk of embolic escape. This tight wrapping design further enhances the overall structural integrity and stability of the device, maintaining a stable shape and position within the complex intravascular environment and resisting deformation or displacement, thereby ensuring effective embolic protection. Furthermore, the full wrapping of the umbrella-shaped filter membrane around the adaptive skirt structure 4 ensures that emboli attached to the skirt structure will not escape from the device during retrieval due to contraction of the skirt structure, thereby improving the device's embolic capture rate.

[0070] Specifically, a first developing element 70 is provided at the skeleton fixing section 31 of the transport guide wire 1. The first developing element 70 is fixedly connected to the skeleton fixing section 31 of the umbrella-shaped skeleton 3. The skeleton fixing section 31 can be fixed to the proximal end of the first developing element 70 by a laser welding process, etc., and is slidably connected to the transport guide wire 1, thereby improving the controllability of the umbrella-shaped skeleton 3 and the transport guide wire 1. In this embodiment, the first developing element 70 can be made of a developing material that is not transparent to X-rays, and the developing material is one or more of gold, tungsten, platinum, and platinum-iridium alloy, and has a good developing effect. The first developing element 70 can be a developing ring, or a cylindrical spiral developing coil, etc., which is not specifically limited in this application. The first developing element 70 is preferably a developing ring, which can help the operator quickly capture position information.

[0071] A second developing element 71 is provided at the tail end 21 of the filter mesh 2 of the conveying guide wire 1. The second developing element 71 is fixedly connected to the tail end 21 of the filter mesh 2. The tail end 21 of the filter mesh 2 can be fixed to the second developing element 71 by gluing or hot melting, and is slidably connected to the conveying guide wire 1, thereby improving the controllability of the filter mesh 2 and the conveying guide wire 1. In this embodiment, the second developing element 71 can be made of a developing material that is not transparent to X-rays, and the developing material is one or more of gold, tungsten, platinum, and platinum-iridium alloy, and has a good developing effect. The second developing element 71 can be a developing ring, or a cylindrical spiral developing coil, etc., which is not specifically limited in this application. The second developing element 71 is preferably a developing ring, which can help the operator quickly capture position information.

[0072] A third imaging element (not shown) may also be provided on the outer wall of the main frame segment 33. This third imaging element may be made of an X-ray-opaque imaging material, such as one or more of gold, tungsten, platinum, or a platinum-iridium alloy, for excellent imaging performance. The third imaging element may be a imaging ring, a cylindrical helical imaging coil, or a imaging coating applied to the outer wall of the main frame segment 33. In this embodiment, the third imaging element is constructed from a radiopaque wire spring and is used to quickly capture the expanded and contracted states of the umbrella-shaped frame 3.

[0073] Furthermore, an elastic tip 8 is provided at the distal end of the delivery guide wire 1 and is fixed to the delivery guide wire 1 by bonding or laser welding. The elastic tip 8 acts as a shock absorber to prevent the embolic protection device from causing damage to the blood vessel during the delivery or recovery process. Specifically, the elastic tip 8 is an integrated spring and is formed by 3D printing of a flexible material, which can ensure that it has good elasticity and flexibility. At the same time, the integrated design reduces the connection gaps and potential breaking points between components, and improves the stability and reliability of the structure. In addition, 3D printing technology can accurately control the shape, size and elastic properties of the spring, so that it can better adapt to the bends and narrow parts of the blood vessels, further enhancing the protective effect. The flexible material can be a soft material such as silicone, polyurethane, etc., which can not only provide buffering properties, but also have good biocompatibility, reduce the risk of postoperative complications, and contribute to the rapid recovery of patients.

[0074] Furthermore, it should be noted that the nano-scale antispasmodic drug spheres 5 are not specifically limited in this application. Figure 9 As shown, microspheres can be formed by adsorbing an antispasmodic drug layer 50 (such as atropine, papaverine hydrochloride, heparin, flunarizine hydrochloride, etc.) on a polymer matrix 51 such as water-soluble chitosan, polylactic acid, hydrogel, etc. Of course, other structures can also be used as long as the antispasmodic effect can be achieved.

[0075] The adaptive vascular embolic protection device of the present invention generally works as follows:

[0076] like Figure 2 As shown, the delivery catheter transports the embolic protection device to a suitable location (such as the location of carotid artery stenosis), and the delivery catheter gradually withdraws to release the embolic protection device, and the umbrella-shaped frame 3 automatically opens. Figure 3 As shown, after the umbrella-shaped skeleton 3 is fully released, that is, the umbrella-shaped skeleton 3 is in a fully expanded state, the adaptive skirt structure 4 absorbs liquid and expands. The gap between the adaptive skeleton and the blood vessel wall greatly improves the wall adhesion and stability of the embolic protection device. As the adaptive skirt structure 4 expands, it squeezes the nano-scale antispasmodic drug spheres 5 filled in the skirt micropores. The nano-scale antispasmodic drug spheres 5 are freely released, and the drug layer of the nano-scale antispasmodic drug spheres 5 dissolves and acts on the blood vessel wall, which can greatly reduce the risk of carotid artery spasm during surgery. Figure 4 As shown, the delivery catheter is completely withdrawn, and the adaptive skirt structure 4 self-expands to fill the gap between the umbrella-shaped skeleton 3 and the blood vessel wall. At the same time, the soft hem of the adaptive skirt structure 4 can alleviate the stimulation of the embolic protection device on the blood vessel and reduce the risk of carotid artery vasospasm.

[0077] like Figure 5As shown, even when facing a blood vessel wall 91 of uneven size, the adaptive skirt structure 4 can adapt to the gap between the umbrella-shaped frame 3 and the blood vessel wall according to actual conditions, providing the embolic protection device with good wall-adhering performance.

[0078] like Figure 6 As shown, when the embolic protection device is released at different positions, the adaptive skirt structure 4 can perfectly fill the gap between the umbrella-shaped skeleton 3 and the blood vessel wall.

[0079] like Figure 7 Figure 2 illustrates the retrieval process of the embolic protection device. The retrieval catheter 92 pushes the umbrella-shaped frame 3 forward and compresses the liquid absorbed by the adaptive skirt structure 4, allowing the embolic protection device to enter the retrieval catheter. If excessive thrombus is trapped in the filter element 2, only the umbrella-shaped frame 3 can enter the retrieval catheter, preventing leakage of thrombus caused by forced retrieval of the embolic protection device.

[0080] A second object of the present invention is to provide an embolization system comprising a delivery catheter 90 and the aforementioned adaptive vascular embolic protection device. The delivery catheter 90 is provided with a delivery channel, and the adaptive vascular embolic protection device is slidably disposed within the delivery channel of the delivery catheter 90. This embolization system possesses all the technical features and at least all the advantages of the aforementioned adaptive vascular embolic protection device, and will not be further elaborated herein.

[0081] To ensure smooth delivery and retrieval of the filter element 2, the embolic protection device of the present invention can be used in conjunction with delivery / retrieval systems known in the art. For example, the embolic protection device can be compressed and loaded into the delivery channel of a delivery catheter 90. Upon reaching the intended use position, it can be released and then self-expand to an extended, or deployed, state. Correspondingly, after the embolic protection device is released intraluminally, the adaptive skirt structure 4 autonomously expands and contracts to fill the gap between the main frame segment and the vessel wall, providing excellent wall adhesion and avoiding the gaps that can occur in curved vessels with conventional embolic protection devices, allowing microemboli to escape.

[0082] The present invention is further described above with the aid of specific embodiments. However, it should be understood that the specific description herein should not be construed as limiting the essence and scope of the present invention. Various modifications made to the above embodiments by ordinary technicians in this field after reading this specification are all within the scope of protection of the present invention.

Claims

1. An adaptive vascular embolic protection device, characterized by: It includes: Delivery guidewire; A filter mesh having an open end and a closed end, wherein the filter mesh is sleeved on the delivery guide wire, with the open end of the filter mesh facing the proximal end of the delivery guide wire, and is used for filtering emboli; An umbrella-shaped frame is sleeved on the conveying guide wire and arranged at the open end of the filter mesh; An adaptive skirt structure having micropores surrounding and covering the open and closed ends of the umbrella-shaped frame, and the open end of the filter element covering the outside of the adaptive skirt structure; Nano-scale antispasmodic drug spheres are filled in the micropores of the adaptive skirt structure; Wherein, the umbrella-shaped frame has an expanded state and a contracted state; In the expanded state, the opening and closing ends of the umbrella-shaped frame are fully opened, and the adaptive skirt structure absorbs liquid to expand and conform to the target blood vessel wall; and when the adaptive skirt structure expands, the nano-scale antispasmodic drug spheres filled in the micropores of the adaptive skirt structure are squeezed and released and dissolved; The umbrella-shaped frame includes a frame fixing section, a frame transition section, and a frame main section, which are sequentially connected from the proximal end to the distal end; when the umbrella-shaped frame is in an expanded state, the radial internal spaces of the frame fixing section, the frame transition section, and the frame main section increase sequentially; The adaptive skirt structure is arranged circumferentially along the outer wall of the skeleton main body section, covering at least one circle; Furthermore, the edge of the adaptive skirt structure on the main frame segment is connected to the proximal surface of the transition segment of the frame.

2. The adaptive vascular embolic protection device according to claim 1, characterized in that: The surface of the delivery guide wire is coated with a lubricating coating.

3. The adaptive vascular embolic protection device according to claim 1, characterized in that: Limiting rings are provided on the conveying guide wire and on both sides of the filter mesh and the umbrella-shaped frame, for limiting the movement of the filter mesh and the umbrella-shaped frame on the conveying guide wire.

4. The adaptive vascular embolic protection device according to claim 1, characterized in that: The filter mesh is an umbrella-shaped filter membrane, the open end of which is covered on the outer wall side of the adaptive skirt structure and extends to cover the skeleton transition section.

5. The adaptive vascular embolic protection device according to claim 1, characterized in that: A first developing element is provided at the frame fixing section of the delivery guide wire, the first developing element is fixedly connected to the frame fixing section of the umbrella-shaped frame, and is slidably connected to the delivery guide wire; And / or a second developing element is provided at the tail end of the filter mesh of the conveying guide wire, the second developing element is fixedly connected to the tail end of the filter mesh and is slidably connected to the conveying guide wire.

6. The adaptive vascular embolic protection device according to claim 1, characterized in that: The outer wall of the skeleton main body section is provided with a third developing element.

7. The adaptive vascular embolic protection device according to claim 1, characterized in that: An elastic tip is provided at the distal end of the delivery guide wire.

8. An embolization system, characterized in that: It includes a delivery catheter and the adaptive vascular embolic protection device according to any one of claims 1 to 7, wherein a delivery channel is provided in the delivery catheter, and the adaptive vascular embolic protection device is slidably arranged in the delivery channel of the delivery catheter.

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