Automatic scanning device for medical pathology sections
By designing a pathological slice automatic scanning device including a first moving plate and a connecting shaft, the problem of focusing failure caused by damage to the objective lens or adhesion of impurities in the prior art is solved, and the stable scanning of the slide and the normal use of the objective lens are realized, and the protection of the sterile environment is ensured.
Patent Information
- Application Number
- CN202411440206.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-15
- Publication Date
- 2025-05-13
- Estimated Expiration
- 2044-10-15
AI Technical Summary
During the focusing process, existing pathological section scanners fail to focus due to damage to the objective lens or impurities, which in turn leads to broken slides, affecting the normal use of the objective lens.
An automatic scanning device for medical pathological slices is designed to drive the first moving block and slide downward through the first moving plate to avoid focusing failure caused by damage to the objective lens or adhesion of impurities; at the same time, the second moving plate is driven to rotate through the connecting shaft, and the moving distance of the objective lens is adjusted to ensure that the focusing process of the high-magnitude objective lens is not affected.
It effectively avoids the focus failure caused by the objective lens breakage or the adhesion of impurities, prevents the glass slide from breaking, and ensures the normal use of the objective lens. At the same time, through the concentration of the storage shell and the coordination of the elastic parts, the stability of the glass slide during the scanning process and the protection of the sterile environment are ensured.
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Figure CN118961591B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of pathological slice scanning devices and proposes an automatic scanning device for medical pathological slices. Background Art
[0002] Pathological examination is a morphological method for examining pathological changes in the body's organs, tissues or cells. It requires cutting a certain size of diseased tissue, making pathological sections through histological methods, and using a digital slicing system to quickly scan the entire slide. The pathological diagnosis is solved through a network communication control system.
[0003] Existing pathology slice scanners usually require doctors to place slides and cover slips on a slide tray, and then the numerical control device moves the scanner's objective lens downward to a suitable position to focus the objective lens. However, during the focusing process, if the objective lens is attached with impurities or is damaged, the objective lens will not be able to refract light correctly, resulting in a focus failure of the objective lens. After the focus failure, a clear magnified image cannot be formed in the scanner, and the numerical control device cannot receive a stop signal and continues to move the objective lens downward, causing the objective lens to contact the cover glass, squeezing the cover glass and then squeezing the slide, causing the slide and cover glass to break at the same time. The broken glass slide (hereinafter referred to as glass slide refers to slide and cover glass) will also scratch the objective lens, affecting the normal use of the objective lens. Summary of the invention
[0004] In order to overcome the shortcomings mentioned in the above background technology, the present invention provides an automatic scanning device for medical pathology slices.
[0005] The technical implementation scheme of the present invention is as follows: an automatic scanning device for medical pathological slices, comprising a bracket, a first movable plate is slidably connected inside the bracket, an electronic light source is arranged on the bracket, a driving device for changing the position of the first movable plate is arranged on the bracket, a connecting tube is fixedly connected to the side of the first movable plate away from the bracket, a shooting device is arranged on the connecting tube, a switch is rotatably fixedly connected to the side of the connecting tube away from the first movable plate, an objective lens is arranged on the side of the switch away from the connecting tube, an electric slider is installed on the side of the bracket away from the connecting tube, an electric rotating shaft is rotatably connected to the upper side of the electric slider, a fixed disk is fixedly connected to the side of the electric rotating shaft close to the connecting tube, a symmetrical and circumferentially uniformly distributed limiting block is fixedly connected to the side of the fixed disk close to the electric slider, the fixed disk is provided with circumferentially uniformly distributed through holes, a first movable block is slidably connected in the through hole of the fixed disk, the first movable block is provided with a through hole, a symmetrically distributed fixer is detachably connected to the first movable block, adjacent fixers are commonly provided with a glass slide, and a first elastic member is arranged between the first movable block and the adjacent limiting block.
[0006] Furthermore, the bracket is slidably connected to a first connecting block inside the bracket, the first connecting block is extruded and matched with the first movable plate, a pressure sensor is provided on the first connecting block, the bracket is provided with a hydraulic telescopic rod through a connecting mechanism, the telescopic end of the hydraulic telescopic rod is fixedly connected to the first connecting block, the first movable block is fixedly connected to a symmetrically distributed second connecting block on the side away from the connecting tube, the bracket is fixedly connected to a symmetrically distributed fixed tube, the symmetrically distributed fixed tubes are all connected to the fixed part of the hydraulic telescopic rod through the connecting tube, the fixed tube is slidably connected to a push plate inside the fixed tube, a second elastic member is provided between the push plate and the adjacent fixed tube, the push plate is fixedly connected to a moving rod, the moving rod is sealingly and slidably connected to the adjacent fixed tube, the moving rod is fixedly connected to a fixed block at one end away from the adjacent push plate, and the second connecting block is provided with an arc groove slidably connected to both the adjacent fixed block and the adjacent moving rod.
[0007] Furthermore, the arc-shaped groove on the second connecting block is concentric with the fixing plate.
[0008] Further, the connecting mechanism includes a liquid storage ring, which is embedded in one side of the connecting tube, and the liquid storage ring is slidably connected to a moving ring, and a second moving plate is fixedly connected to a side of the moving ring away from the liquid storage ring, and the second moving plate is slidably connected to the connecting tube, and the second moving plate is embedded with a rolling ball, and a connecting shaft is rotatably connected to a side of the connecting tube away from the bracket, and the connecting shaft is connected to the rotating shaft of the switcher through a universal joint, and the connecting shaft is provided with an arc groove that slidably cooperates with the rolling ball on the second moving plate, and a sealing block is fixedly connected to the fixed part of the hydraulic telescopic rod, and a liquid storage tube is fixedly connected to a side of the bracket away from the connecting tube, and the sealing block is sealingly and slidably connected to the liquid storage tube, and the liquid storage tube and the liquid storage ring are connected through a connecting pipe.
[0009] Furthermore, the angle of the rotation path of the arc groove on the connecting shaft is 360°, and the height of the arc groove on the connecting shaft in the vertical direction is the same as the height of the moving ring.
[0010] Furthermore, it also includes a limit ring, which is fixedly connected to the electric slider, and the limit ring is rotatably connected to the fixed plate, the first movable block is slidably connected to symmetrically distributed extrusion blocks, the extrusion blocks are extruded and matched with the limit ring, the first movable block is slidably connected to a symmetrically distributed second movable block, the second movable block is extruded and matched with the adjacent extrusion block, the second movable block is fixedly connected to an elastic telescopic rod on one side close to the adjacent fixer, the telescopic end of the elastic telescopic rod is fixedly connected to a push plate, and the push plate is in contact and matched with the adjacent fixer.
[0011] Furthermore, the elastic coefficient of the first elastic member is greater than the elastic coefficient of the elastic telescopic rod.
[0012] Furthermore, a side of the limiting ring close to the electric slider is configured in a stepped shape.
[0013] Furthermore, the first moving block is rotatably connected to an L-shaped plate distributed in a matrix, a third elastic member is provided between the L-shaped plate and the adjacent first moving block, the L-shaped plate is squeezed and matched with the adjacent fixer, and the L-shaped plate is limitedly matched with the fixed disk.
[0014] Furthermore, a storage shell is fixedly connected to one side of the first movable block away from the connecting tube, the through hole on the first movable block is connected to the adjacent storage shell, the lower side inside the storage shell is configured to be convex, and the storage shell is made of glass to increase the light-gathering property of the storage shell.
[0015] The beneficial effect is as follows: when the connecting tube moves downward to a designated position, the first moving plate drives the first moving block to move downward, thereby driving the glass slide to move downward, thereby preventing the connecting tube from continuously moving downward to squeeze the glass slide and break the glass slide when the objective lens is damaged or debris attached thereto and the focus cannot be focused during the downward movement of the connecting tube;
[0016] The second movable plate is driven to rotate by the connecting shaft, and the position of the first connecting block is adjusted during the switching of the objective lens, thereby adjusting the downward moving distance of the objective lens to avoid affecting the focusing process of the high-magnification objective lens.
[0017] The protrusion of the storage shell gathers the electronic light source, so that the device can quickly focus light during the scanning of the glass slide. At the same time, the storage shell stores the broken glass slide to prevent the broken glass slide from affecting the inspection and scanning of the remaining intact glass slides, and to prevent the pathological samples on the glass slide from leaking after the glass slide is broken, thereby affecting the sterile environment of the device.
[0018] Through the cooperation between the extrusion block and the limiting ring, the glass slide is located in the middle of the adjacent first moving block during scanning. At the same time, through the cooperation between the L-shaped plate and the adjacent first moving block, the adjacent glass slide is fixed to prevent the position of the glass slide from changing during the scanning process, which affects the scanning result of the sample on the glass slide. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;
[0020] Figure 2 It is a three-dimensional structural schematic diagram of the positional relationship between the electric slider and the electric rotating shaft of the present invention;
[0021] Figure 3 It is a three-dimensional structural schematic diagram of the internal parts of the fixed plate of the present invention;
[0022] Figure 4 It is a schematic diagram of the three-dimensional structure of the limit block and the first moving block of the present invention;
[0023] Figure 5 It is a schematic diagram of the three-dimensional structure of the liquid storage ring and the moving ring of the present invention;
[0024] Figure 6 It is a schematic diagram of the three-dimensional structure of the second movable plate and the connecting shaft of the present invention;
[0025] Figure 7 It is a three-dimensional structural schematic diagram of the electric slider and the limiting ring of the present invention;
[0026] Figure 8 It is a three-dimensional structural schematic diagram of the matching relationship between the fixing plate and the L-shaped plate of the present invention;
[0027] Fig. 9 It is a schematic diagram of the three-dimensional structure inside the storage shell of the present invention;
[0028] Fig.10 It is a schematic diagram of the three-dimensional structure of the extrusion block and the second moving block of the present invention.
[0029] 1. The markings in the accompanying drawings are: 1. bracket, 2. first movable plate, 3. connecting cylinder, 4. switch, 5. electric slider, 501. electric rotating shaft, 6. fixed plate, 7. limit block, 8. first movable block, 9. fixer, 10. first elastic member, 21. first connecting block, 22. hydraulic telescopic rod, 23. second connecting block, 24. fixed tube, 25. push plate, 251. second elastic member, 26. movable rod, 27. fixed block, 31. liquid storage ring, 32. movable ring, 33. second movable plate, 34. connecting shaft, 35. sealing block, 36. liquid storage tube, 42. limit ring, 43. extrusion block, 44. second movable block, 45. elastic telescopic rod, 46. push plate, 51. L-shaped plate, 52. third elastic member, 61. storage shell. DETAILED DESCRIPTION
[0030] When scanning a glass slide using a pathology section scanner, the objective lens needs to be moved downward to a suitable position first to focus the objective lens. Considering that the objective lens may be attached with some impurities or the objective lens may be damaged, resulting in a focus failure. After the focus failure, a clear magnified image cannot be formed in the scanner. The numerical control device continues to move the objective lens downward because it does not receive a stop signal, causing the objective lens to squeeze the glass slide, resulting in the glass slide breaking. In this regard, the present invention avoids the above situation through the following operations:
[0031] The preferred technical solutions of the present invention are described in detail below with reference to the accompanying drawings.
[0032] Example 1: A medical pathology slice automatic scanning device, please combine Figure 1-Figure 4Read this paragraph, including a bracket 1, a first movable plate 2 is slidably connected inside the bracket 1, an electronic light source electrically connected to a control terminal is arranged on the bracket 1 (it is an existing device, not shown in the figure), the bracket 1 is provided with a driving device for changing the position of the first movable plate 2, the driving device is a motor (it is an existing device not shown in the figure) and a threaded rod, the motor is electrically connected to the control terminal, a connecting tube 3 is fixedly connected to the left side of the first movable plate 2, a shooting device electrically connected to the control terminal is arranged on the connecting tube 3, the connecting tube 3 is driven by the driving device to move through the first movable plate 2, a switch 4 is rotatably fixedly connected to the lower side of the connecting tube 3, an objective lens is arranged on the lower side of the switch 4, the objective lens is replaced by the switch 4, an electric slider 5 electrically connected to the control terminal is installed on the left side of the bracket 1, an electric rotating shaft 501 electrically connected to the control terminal is rotatably connected to the upper side of the electric slider 5, a fixed disk 6 is fixedly connected to the upper side of the electric rotating shaft 501, and the electric rotating shaft 501 drives the fixed disk 6 to rotate. The fixed plate 6 rotates, and the electric slider 5 drives the fixed plate 6 to move through the transmission of the electric rotating shaft 501. Four groups of limit blocks 7 uniformly distributed in the circumferential direction are fixedly connected to the lower side of the fixed plate 6, and each group is set to two limit blocks 7 symmetrically distributed. The fixed plate 6 is provided with four through holes uniformly distributed in the circumferential direction. The first moving block 8 is slidably connected in the through hole of the fixed plate 6. The first moving block 8 is provided with a through hole. The first moving block 8 is detachably connected with a symmetrically distributed fixer 9. The two fixers 9 on the same first moving block 8 are jointly provided with a glass slide. The fixed plate 6 drives the glass slide to rotate through the first moving block 8 and the fixer 9, adjusts the position of the glass slide, and completes the switching of the scanned glass slide. A first elastic member 10 is provided between the first moving block 8 and the adjacent limit block 7. The first elastic member 10 is a spring. The first elastic member 10 is used to maintain the initial position of the adjacent first moving block 8 and drive the first moving block 8 to reset to the initial position after movement.
[0033] Please combine Figure 2 and Figure 3Reading this paragraph, the bracket 1 is internally slidably connected with a first connecting block 21, the first connecting block 21 is pressed and matched with the first movable plate 2, the first connecting block 21 is provided with a pressure sensor electrically connected to the control terminal, and the pressure sensor detects the extrusion force on the first connecting block 21, and the right side of the bracket 1 is provided with a hydraulic telescopic rod 22 through a connecting mechanism, the hydraulic telescopic rod 22 is located below the first connecting block 21, and the telescopic end of the hydraulic telescopic rod 22 is fixedly connected to the first connecting block 21, and the connecting mechanism is changed by changing the fixed part of the hydraulic telescopic rod 22. The position of the first connecting block 21 is changed, the lower side of the first moving block 8 is fixedly connected with a symmetrically distributed second connecting block 23, the bracket 1 is fixedly connected with two fixed pipes 24 symmetrically distributed front and back, the two fixed pipes 24 are connected with the fixed part of the hydraulic telescopic rod 22 through the connecting pipe, the telescopic part of the hydraulic telescopic rod 22 moves downward, and the hydraulic oil in its fixed part is transported to the two fixed pipes 24 through the connecting pipe, the interior of the fixed pipe 24 is slidably connected with a push plate 25, and the upper side of the push plate 25 and the adjacent fixed pipe 24 are filled with hydraulic oil, and the delivery The hydraulic oil in the fixed pipe 24 flows between it and the adjacent push plate 25, so that the volume of the hydraulic oil in the push plate 25 and the adjacent fixed pipe 24 increases, thereby driving the push plate 25 to move downward. A second elastic member 251 is provided between the push plate 25 and the adjacent fixed pipe 24. The second elastic member 251 is a tension spring. The second elastic member 251 is used to maintain the initial position of the adjacent push plate 25 and drive the push plate 25 to return to the initial position after the movement. The two second elastic members 251 cooperate with each other to increase the volume of the hydraulic oil delivered to the two fixed pipes 24. The area is maintained consistent, a moving rod 26 is fixedly connected to the upper side of the push plate 25, and the moving rod 26 is sealed and slidably connected to the adjacent fixed tube 24. A fixed block 27 is fixedly connected to the upper end of the moving rod 26. The second connecting block 23 is provided with an arc groove that is slidably connected to the adjacent fixed block 27 and the adjacent moving rod 26, and the arc groove on the second connecting block 23 is concentric with the fixed plate 6. The push plate 25 drives the adjacent first moving block 8 to move synchronously through the transmission of the adjacent moving rod 26, and then drives the adjacent glass slides to move synchronously, so as to prevent the adjacent glass slides from being squeezed and broken by the objective lens.
[0034] Please combine Figure 2 , Figure 5 and Figure 6Reading this paragraph, the connecting structure includes a liquid storage ring 31, the interior of the liquid storage ring 31 is filled with hydraulic oil, the liquid storage ring 31 is embedded in the left side of the connecting tube 3, and the lower side of the liquid storage ring 31 is slidably connected with a moving ring 32, and the lower side of the moving ring 32 is fixedly connected with a second moving plate 33, the second moving plate 33 is slidably connected to the connecting tube 3, and the second moving plate 33 is embedded with a rolling ball. The left side of the lower part of the connecting tube 3 is rotatably connected with a connecting shaft 34, and the connecting shaft 34 is connected to the rotating shaft of the switch 4 through a universal joint. During the rotation process, the switch 4 drives the connecting shaft 34 to rotate synchronously through the transmission of the universal joint. The connecting shaft 34 is provided with an arc groove that slidably cooperates with the rolling ball on the second moving plate 33. During the rotation process, the connecting shaft 34 drives the second moving plate 33 to move up and down, and then drives the moving ring 32 to move up and down. The angle of the rotation path of the arc groove on the upper part of the connecting shaft 34 is 360°, and the vertical height of the arc groove on the connecting shaft 34 is the same as the height of the moving ring 32, ensuring that the second moving plate 33 can drive the moving ring 32 to move upward to the limit position synchronously when it moves upward to the limit position. The fixed part of the hydraulic telescopic rod 22 is fixedly connected with a sealing block 35, and the right side of the bracket 1 is fixedly connected with a liquid storage pipe 36. The sealing block 35 and the liquid storage pipe 36 are sealed and slidably connected. The upper side of the sealing block 35 and the liquid storage pipe 36 are filled with hydraulic oil. The liquid storage pipe 36 and the liquid storage ring 31 are connected through a connecting pipe. The connecting pipe is located at the lower side of the sealing block 35. When the moving ring 32 moves upward, the hydraulic oil inside the liquid storage ring 31 is transported to the liquid storage pipe 36 through the connecting pipe, so that the sealing block 35 moves upward, thereby changing the position of the fixed part of the hydraulic telescopic rod 22.
[0035] When using this device, the staff places the glass slide between the two fixtures 9, then places the two fixtures 9 and the glass slides thereon on the first first moving block 8, and adjusts them to a suitable position, then the control terminal starts the electric rotating shaft 501, and the electric rotating shaft 501 drives the fixed plate 6 to rotate, and adjusts the position of the first glass slide thereon, until the first glass slide rotates 90°, the control terminal shuts down the electric rotating shaft 501, and places the second glass slide on the second first moving block 8 according to the above operation, then the control terminal continues to start the electric rotating shaft 501 according to the above operation, until the electric rotating shaft 501 rotates 270°, and glass slides are placed on the four first moving blocks 8.
[0036] After the electric shaft 501 rotates 270°, the control terminal turns off the electric shaft 501 and starts the driving device at the same time, and the driving device drives the first movable plate 2 to move downward, and the first movable plate 2 drives the connecting tube 3 to move downward, and the connecting tube 3 drives the switch 4 and the objective lens thereon to move downward synchronously to adjust the focal length of the objective lens to a suitable state. After the focal length of the objective lens is adjusted, the control terminal turns off the driving device and starts the electronic light source at the same time, and adjusts the electronic light source so that the electronic light source can be focused on the objective lens. Then the control terminal starts the shooting device, and the shooting device scans and shoots the sample on the glass slide. During the scanning process, the control terminal changes the position of the fixed disk 6 through the electric slider 5, and then fine-tunes the position of the glass slide to ensure that the objective lens can fully cover the sample during the scanning process of the shooting device on the sample on the glass slide.
[0037] After the scanning of the sample on the glass slide is completed, the control terminal turns off the shooting device and the electronic light source and starts the driving device in reverse, and the driving device drives the first movable plate 2 and other parts connected thereto to reset upward, and the control terminal continues to start the electric rotating shaft 501 (with Figure 1 The electric rotating shaft 501 rotates clockwise), and after the scanned glass slide is transported for 90°, the control terminal shuts down the electric rotating shaft 501 again, and the staff replaces the scanned glass slide and continues to scan the remaining glass slides according to the above operation.
[0038] In the process of the fixed disk 6 driving the first movable block 8 to rotate, the first movable block 8 drives the two adjacent second connecting blocks 23 to rotate synchronously. After the two second connecting blocks 23 on the front side rotate 270°, the two second connecting blocks 23 on the front side rotate to the right side, and the arc grooves on the lower sides of the two second connecting blocks 23 contact the adjacent fixed blocks 27 respectively.
[0039] In the process of the above-mentioned control terminal adjusting the position of the connecting tube 3 through the driving device, when the first movable plate 2 moves downward to the position in contact with the first connecting block 21, the first movable plate 2 drives the first connecting block 21 to move downward synchronously, and the first connecting block 21 drives the telescopic end of the hydraulic telescopic rod 22 to move downward synchronously, so that the telescopic end of the hydraulic telescopic rod 22 retracts into its fixed part, and the hydraulic oil in its fixed part is transported to the two fixed pipes 24 through the connecting pipe.
[0040] The hydraulic oil delivered to the fixed pipe 24 flows between it and the adjacent push plate 25, so that the push plate 25 is squeezed by the adjacent hydraulic oil and moves downward, and the adjacent second elastic member 251 is stretched and stored, and the push plate 25 drives the adjacent moving rod 26 to move downward synchronously, and the moving rod 26 drives the adjacent fixed block 27 to move downward, and the fixed block 27 drives the adjacent second connecting block 23 to move downward, and the second connecting block 23 drives the adjacent first moving block 8 to move downward, and at the same time compresses the two adjacent first elastic members 10, and the first moving block 8 drives the glass slide thereon to move downward synchronously, and at this time, the downward movement speed of the first moving block 8 is the same as the downward movement speed of the connecting tube 3, that is, the downward movement speed of the glass slide is the same as the downward movement speed of the connecting tube 3, so as to avoid the objective lens being unable to focus due to damage or debris attached thereto during the downward movement of the connecting tube 3, causing the connecting tube 3 to continue to move downward, so that the objective lens on the switcher 4 squeezes the glass slide, causing the glass slide to break.
[0041] When the first movable plate 2 contacts the first connecting block 21 (the first connecting block 21 is at the initial position at this time, and when the first movable plate 2 moves downward to the position in contact with the first connecting block 21, the objective lens of the switch 4 moves synchronously to the position in contact with the glass slide, which is the safety position for the switch 4 to move downward), the value detected by the pressure sensor on the first connecting block 21 increases, and the control terminal issues an alarm to remind the staff that the distance the connecting tube 3 moves downward is too large, and the staff shuts down the device, inspects the device, and removes the glass slides on the four first movable blocks 8. Under, until the maintenance of the device is completed, the staff resets the connecting cylinder 3 to the initial position. During the resetting process of the connecting cylinder 3, the squeezing force of the first movable plate 2 on the first connecting block 21 is gradually reduced, so that the pulling force on the two second elastic members 251 is gradually reduced synchronously, and then the two second elastic members 251 are gradually reset to the initial state, and drive the adjacent push plates 25 and other parts connected thereto to reset to the initial position synchronously, and the push plate 25 re-transports the hydraulic oil between it and the adjacent fixed pipe 24 to the fixed part of the hydraulic telescopic rod 22, so that the telescopic end of the hydraulic telescopic rod 22 drives the first connecting block 21 to reset to the initial position.
[0042] In the process of scanning the sample on the glass slide using the device, when it is necessary to switch the high-power objective lens, the staff rotates the switch 4 according to the type of sample to switch the objective lens of the appropriate power. During the rotation of the switch 4, the rotating shaft of the switch 4 drives the connecting shaft 34 to rotate through the universal joint. The second moving plate 33 is limited by the arc groove on the connecting shaft 34 and moves upward with the rotation of the connecting shaft 34. The second moving plate 33 drives the moving ring 32 to move upward synchronously, so that the moving ring 32 moves into the liquid storage ring 31 and the liquid in the liquid storage ring 31 is filled. The hydraulic oil is squeezed into the liquid storage tube 36 through the connecting tube, so that the volume of the hydraulic oil between the liquid storage tube 36 and the sealing block 35 increases, thereby causing the sealing block 35 to move upward, and the sealing block 35 drives the fixed part of the hydraulic telescopic rod 22 to move upward synchronously, and the telescopic end of the hydraulic telescopic rod 22 drives the first connecting block 21 to move upward synchronously, and the position of the first connecting block 21 is adjusted, that is, the distance between the first connecting block 21 and the first movable plate 2 is adjusted, and then the safety position of the objective lens moving downward is adjusted to avoid affecting the focusing process of the high-magnification objective lens.
[0043] At present, when using a pathology scanner, the staff only places the glass slide in the groove on the stage without effectively fixing the glass slide, which makes the glass slide easily shaken by the outside world during the movement, thereby affecting the film quality of the scanner. In this regard, the present invention avoids the above situation through the following operations:
[0044] Example 2: Based on Example 1, please combine Figure 2 and Figure 7-10 Reading this paragraph, it also includes a limit ring 42, the lower side of the inner part of the limit ring 42 is set to be stepped, and the limit ring 42 is divided into two steps (with the tangent point on the right side of the limit ring 42 as the reference point, and Figure 2The top view angle is the reference angle, the limiting ring 42 is provided with a notch at the position of 45°-135° clockwise from the reference point, the limiting ring 42 is the first step at the position of 135°-225° from the reference point, and is the second step at the position of 225°-45°, and the height of the lower side of the first step is greater than the height of the lower side of the second step), the limiting ring 42 is fixedly connected to the electric slider 5, the limiting ring 42 is rotatably connected to the fixed disk 6, the first moving block 8 is slidably connected with symmetrically distributed extrusion blocks 43, the fixed disk 6 drives the extrusion block 43 to rotate through the transmission of the first moving block 8, the extrusion block 43 is extruded and matched with the limiting ring 42, and the extrusion block 43 moves downward due to the extrusion of the step position on the limiting ring 42 during the rotation process, the first moving block 8 is internally slidably connected with a symmetrically distributed second moving block 44, the second moving block 44 is extruded and matched with the adjacent extrusion block 43, and the extrusion block 43 is extruded in the process of moving downward During the process, the adjacent second moving block 44 is driven to move synchronously, and two symmetrically distributed elastic telescopic rods 45 are fixedly connected to one side of the second moving block 44 close to the adjacent fixer 9, and the telescopic end of the elastic telescopic rod 45 is fixedly connected with a push plate 46, and the push plate 46 contacts and cooperates with the adjacent fixer 9. The second moving block 44 drives the adjacent push plate 46 to move synchronously through the transmission of the adjacent elastic telescopic rod 45, and then pushes the center of the two adjacent fixers 9 and the glass slides connected thereto to a position coincident with the center of the adjacent first moving block 8. The elastic coefficient of the first elastic member 10 is greater than the sum of the elastic coefficients of the two adjacent elastic telescopic rods 45, and is used for when the extrusion block 43 contacts the first step on the limit ring 42, the extrusion block 43 moves downward to drive the adjacent second moving block 44 to move, and when the extrusion block 43 contacts the second step on the limit ring 42, the extrusion block 43 drives the adjacent first moving block 8 to move downward synchronously.
[0045] Please combine Figure 8-Figure 10 Reading this paragraph, the first moving block 8 is rotatably connected to four L-shaped plates 51 distributed in a matrix, and a third elastic member 52 is arranged between the L-shaped plate 51 and the adjacent first moving block 8. The third elastic member 52 is a torsion spring. The third elastic member 52 is used to maintain the initial position of the adjacent L-shaped plate 51 and drive the L-shaped plate 51 to reset to the initial position after moving. The L-shaped plate 51 is squeezed and matched with the adjacent fixer 9, and the L-shaped plate 51 is limited and matched with the fixed disk 6. In the process of the first moving block 8 moving downward, the first moving block 8 drives the four adjacent L-shaped plates 51 to move downward synchronously, so that the four adjacent L-shaped plates 51 are limited and rotated by the fixed disk 6. After the L-shaped plate 51 rotates 90°, the L-shaped plate 51 squeezes the adjacent fixer 9, and the four L-shaped plates 51 cooperate with each other to fix the two adjacent fixers 9, and then fix the adjacent glass slides.
[0046] Please combine Figure 8 and Fig. 9Reading this paragraph, a storage shell 61 is fixedly connected to the lower side of the first movable block 8, and the through hole on the first movable block 8 is connected to the adjacent storage shell 61. The lower side inside the storage shell 61 is set to be convex, and the storage shell 61 is made of glass to increase the light-gathering property of the storage shell 61. The storage shell 61 is used to store broken glass slides to prevent pathological samples on the glass slides from leaking after the glass slides are broken.
[0047] In the process of the fixed plate 6 driving the four first moving blocks 8 thereon to rotate, the following is described by taking the rotation process of the front first moving block 8 as an example:
[0048] The first moving block 8 drives the two adjacent squeezing blocks 43 to move synchronously during the rotation process. When the left squeezing block 43 of the two front squeezing blocks 43 rotates to a position in contact with the first step on the limiting ring 42, the left squeezing block 43 moves downward due to the squeezing of the limiting ring 42 as it continues to move. During the downward movement of the left squeezing block 43, the left squeezing block 43 squeezes the adjacent second moving block 44, causing the second moving block 44 to move to the right, and drives the two adjacent elastic telescopic rods 45 to move to the right synchronously. The telescopic ends of the two elastic telescopic rods 45 jointly drive the adjacent push plates 46 to move to the right. The push plates 46 drive the adjacent glass slides to move to the right synchronously through the transmission of the adjacent fixers 9, until the left squeezing block 43 stops moving downward, and the adjacent glass slides stop moving to the right synchronously.
[0049] When the right squeezing block 43 moves to the position in contact with the limiting ring 42, the right squeezing block 43 drives the adjacent glass slide to move synchronously to the left, and the two squeezing blocks 43 cooperate with each other to adjust the position of the adjacent glass slide, so that the glass slide moves to the middle of the adjacent first moving block 8.
[0050] When the squeezing block 43 on the left side rotates to the position in contact with the second step on the limiting ring 42 (at this time, the first moving block 8 on the front side has rotated 90° clockwise, and the glass slide on the front side is located at the left rear part of the fixed plate 6), the left squeezing block 43 continues to move downward due to the squeezing of the second step on the limiting ring 42, and at the same time, the left squeezing block 43 drives the adjacent first moving block 8 and other parts connected thereto to move downward synchronously. At this time, the first moving block 8 drives the four adjacent L-shaped plates 51 to move downward synchronously. In the process of the L-shaped plate 51 moving downward, the L-shaped plate 51 is limited by the fixed plate 6 and rotates, so that the vertical surface of the L-shaped plate 51 rotates to the horizontal plane and contacts the adjacent fixer 9. The adjacent two L-shaped plates 51 cooperate with the adjacent first moving blocks 8 to clamp the adjacent fixer 9, and then fix the adjacent fixer 9 to fix the adjacent glass slide, so as to prevent the position of the glass slide from changing during the scanning process, affecting the scanning result of the sample on the glass slide.
[0051] During the downward movement of the above-mentioned first moving block 8, the first moving block 8 drives the extrusion block 43 on the right to move downward synchronously, and compresses the two adjacent first elastic members 10 until the extrusion block 43 on the right contacts the second step on the limiting ring 42, and the fixed disk 6 has rotated 180° (at this time, the glass slide on the front side rotates to the rear side and is fixed), until the fixed disk 6 rotates 270° (at this time, the glass slide on the front side rotates to the right side), the control terminal shuts down the electric shaft 501, and scans the glass slide on the right side at this time according to the above operation, and the movement process of the remaining extrusion blocks 43 can refer to the above.
[0052] In the above process of scanning the sample rotated to the right glass slide, the light source at the bottom of the device passes through the bottom of the adjacent storage shell 61 and is collected by the tapered portion at the bottom of the adjacent storage shell 61, so that the light source can be quickly collected.
[0053] In the process of the above-mentioned fixed plate 6 driving the glass slide to rotate through the first moving block 8, if the glass slide is broken due to external influences, the broken glass slide falls downward into the adjacent storage shell 61, and at the same time, the two adjacent fixers 9 are respectively subjected to the squeezing force of the adjacent elastic telescopic rods 45, and respectively drive the remaining glass slides thereon to move toward the direction close to the middle of the adjacent storage shell 61, until the two fixers 9 are respectively moved to the position matching the through holes on the first moving block 8, and the fixers 9 drive the remaining glass slides thereon to fall downward into the adjacent storage shell 61, and the storage shell 61 stores the broken glass slides to prevent the broken glass slides from affecting the inspection and scanning of the remaining intact glass slides, and to prevent the pathological samples on the glass slides from leaking after the glass slides are broken, which affects the sterile environment of the device.
[0054] When the broken glass slides are rotated to the front side again, the staff will replace the storage shell 61 storing the broken glass slides and clean the glass slides in the storage shell 61 for next use.
[0055] While the disclosure has been described with respect to only a limited number of embodiments, those skilled in the art, having benefit of this disclosure, will appreciate that numerous other embodiments can be devised which do not depart from the scope of the invention.
Claims
1. A medical pathology slice automatic scanning device, comprising a support (1), wherein a first movable plate (2) is slidably connected inside the support (1), an electronic light source is arranged on the support (1), and a driving device for changing the position of the first movable plate (2) is arranged on the support (1); a connecting tube (3) is fixedly connected to the side of the first movable plate (2) away from the support (1), and a shooting device is arranged on the connecting tube (3); a switch (4) is rotatably fixedly connected to the side of the connecting tube (3) away from the first movable plate (2), and an objective lens is arranged on the side of the switch (4) away from the connecting tube (3); an electric slider (5) is installed on the side of the support (1) away from the connecting tube (3), and an electric rotating shaft (501) is rotatably connected to the upper side of the electric slider (5), wherein: It also comprises a fixed plate (6), the fixed plate (6) being fixedly connected to a side of the electric rotating shaft (501) close to the connecting cylinder (3), a side of the fixed plate (6) close to the electric sliding block (5) being fixedly connected with a symmetrical and circumferentially uniformly distributed limit block (7), the fixed plate (6) being provided with circumferentially uniformly distributed through holes, a first moving block (8) being slidably connected in the through holes of the fixed plate (6), the first moving block (8) being provided with a through hole, a symmetrically distributed fixer (9) being detachably connected to the first moving block (8), adjacent fixers (9) being provided with a glass slide in common, and a first elastic member (10) being provided between the first moving block (8) and the adjacent limit block (7); The support (1) is internally slidably connected to a first connection block (21), the first connection block (21) is pressed and matched with the first movable plate (2), a pressure sensor is provided on the first connection block (21), the support (1) is provided with a hydraulic telescopic rod (22) via a connecting mechanism, the telescopic end of the hydraulic telescopic rod (22) is fixedly connected to the first connection block (21), a side of the first movable block (8) away from the connecting tube (3) is fixedly connected to a symmetrically distributed second connection block (23), the support (1) is fixedly connected to symmetrically distributed fixed pipes (24), the symmetrically distributed fixed pipes (24) are all connected via The tube is connected to the fixed part of the hydraulic telescopic rod (22), the interior of the fixed tube (24) is slidably connected with a push plate (25), a second elastic member (251) is provided between the push plate (25) and the adjacent fixed tube (24), the push plate (25) is fixedly connected with a moving rod (26), the moving rod (26) is sealingly and slidably connected to the adjacent fixed tube (24), one end of the moving rod (26) away from the adjacent push plate (25) is fixedly connected with a fixed block (27), and the second connecting block (23) is provided with an arc groove slidably connected to both the adjacent fixed block (27) and the adjacent moving rod (26).
2. The automatic scanning device for medical pathological sections according to claim 1, characterized in that: The arc-shaped groove on the second connecting block (23) is concentric with the fixing plate (6).
3. The automatic scanning device for medical pathological sections according to claim 1, characterized in that: The connecting mechanism comprises a liquid storage ring (31), the liquid storage ring (31) is embedded in one side of the connecting tube (3), the liquid storage ring (31) is slidably connected to a moving ring (32), a second moving plate (33) is fixedly connected to a side of the moving ring (32) away from the liquid storage ring (31), the second moving plate (33) is slidably connected to the connecting tube (3), a rolling ball is embedded in the second moving plate (33), a connecting shaft (34) is rotatably connected to a side of the connecting tube (3) away from the bracket (1), the The connecting shaft (34) is connected to the rotating shaft of the switch (4) via a universal joint; the connecting shaft (34) is provided with an arc groove that is slidably matched with the rolling ball on the second movable plate (33); a sealing block (35) is fixedly connected to the fixed portion of the hydraulic telescopic rod (22); a liquid storage tube (36) is fixedly connected to the side of the bracket (1) away from the connecting tube (3); the sealing block (35) is sealingly and slidably connected to the liquid storage tube (36); and the liquid storage tube (36) is connected to the liquid storage ring (31) via a connecting pipe.
4. The automatic scanning device for medical pathological sections according to claim 3 is characterized in that: The angle of the rotation path of the arc-shaped groove on the connecting shaft (34) is 360°, and the height of the arc-shaped groove on the connecting shaft (34) in the vertical direction is the same as the height of the moving ring (32).
5. The automatic scanning device for medical pathological sections according to claim 1, characterized in that: The invention also comprises a limit ring (42), wherein the limit ring (42) is fixedly connected to the electric slider (5), the limit ring (42) is rotatably connected to the fixed disk (6), the first moving block (8) is slidably connected to symmetrically distributed extrusion blocks (43), the extrusion blocks (43) are extruded and matched with the limit ring (42), the first moving block (8) is slidably connected to symmetrically distributed second moving blocks (44), the second moving block (44) is extruded and matched with the adjacent extrusion blocks (43), the second moving block (44) is fixedly connected to an elastic telescopic rod (45) on one side close to the adjacent fixer (9), the telescopic end of the elastic telescopic rod (45) is fixedly connected to a push plate (46), the push plate (46) is in contact and matched with the adjacent fixer (9).
6. The automatic scanning device for medical pathological sections according to claim 5, characterized in that: The elastic coefficient of the first elastic member (10) is greater than the elastic coefficient of the elastic telescopic rod (45).
7. The automatic scanning device for medical pathological sections according to claim 5, characterized in that: The side of the limiting ring (42) close to the electric slider (5) is arranged in a stepped shape.
8. The automatic scanning device for medical pathological sections according to claim 5, characterized in that: The first moving blocks (8) are rotatably connected to L-shaped plates (51) distributed in a matrix, a third elastic member (52) is provided between the L-shaped plates (51) and the adjacent first moving blocks (8), the L-shaped plates (51) are pressed and matched with the adjacent fixers (9), and the L-shaped plates (51) are limitedly matched with the fixing disk (6).
9. The automatic scanning device for medical pathological sections according to claim 8, characterized in that: A storage shell (61) is fixedly connected to a side of the first moving block (8) away from the connecting tube (3); a through hole on the first moving block (8) is connected to an adjacent storage shell (61); the lower side of the interior of the storage shell (61) is arranged in a convex shape; and the storage shell (61) is made of glass, so as to increase the light-gathering property of the storage shell (61).
Citation Information
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