A kind of Xiaoer Chaigui antipyretic granules and its preparation device and preparation method

Abstract

The present application discloses a kind of Xiaoer Chaigui antipyretic granules and its preparation device and preparation method, which include a drying device and a detection device for detecting whether the material is completely dried; the detection device includes a detection box, a test mechanism for detecting the hardness of the surface of the material and a test mechanism for detecting the humidity inside the material; the test mechanism includes a sampling component for extracting different positions of the material and a viewing component for detecting the moisture content of the material; the sampling component includes a bracket movably arranged in the detection box, a support frame lifted and arranged on the bracket and a plurality of sampling parts for sampling the material, and the plurality of sampling parts move to different positions of the material. The present application has the characteristics of sweating and relieving the symptoms, clearing away heat and detoxifying, good taste, less loss of effective ingredients, stable quality, safe auxiliary materials, and convenient administration, and is mainly used to treat exogenous fever in children.

Description

Technical Field

[0001] The present application relates to the technical field of traditional Chinese medicine, and in particular to a kind of Chaigui antipyretic granules for children and a preparation device and method thereof. Background Art

[0002] At present, exogenous fever is mainly caused by colds, that is, fever caused by acute upper respiratory tract infection in Western medicine. It can occur in children of any age, and the younger the age, the higher the incidence rate. For children under 5 years old, colds account for half of the diseases in this age group, and for children aged 5 to 12 years old, colds account for 30% of the diseases in this age group. Therefore, exogenous fever is the most common clinical symptom in children. Due to its physiological and pathological characteristics, children's exogenous fever is mostly high fever, which often leads to convulsions, dehydration, and electrolyte disorders, resulting in serious illness. The difficulty in using medicine for children often affects the treatment effect of exogenous fever. According to traditional Chinese medicine, children's fever is mainly caused by the exposure to external evil, which enters the body and turns into heat, and the evil heat is blazing. Children have tender skin, loose pores, and weak defense functions. If there is a sudden change in climate and imbalance of cold and heat, pathogenic evil can easily take advantage of the opportunity to enter. Wind-heat is caused by the evil wind-heat entering the mouth and nose and invading the upper part of the body. The aversion to cold is short-lived, and high fever, cough, thirst, sore throat, red tongue, and rapid pulse appear immediately. This is because the evil is between the Wei Qi, and the treatment should be pungent and cool to penetrate the surface, clear and release heat. That is, the body will sweat and the evil will be eliminated and the heat will subside. Follow the treatment principles of "opening the door to drive away the thief" and "eliminating the evil and stabilizing the body", so that the evil can have a way out and not let the disease go deep.

[0003] At present, the production process of Xiaoer Chaigui Granule is as follows: Cinnamon twig and Bupleurum are crushed, distilled, salted out, and refrigerated to separate volatile oil, and beta-cyclodextrin is added to obtain a paste, which is dried and crushed for later use; Pueraria root is extracted with ethanol percolation to extract flavonoid components; Scutellaria baicalensis is extracted with water and acid precipitation to obtain high-content baicalin; White peony root, duckweed, and cicada shell are decocted and concentrated to make a clear paste; the extracts are mixed and concentrated into a thick paste, and an appropriate amount of sucrose, beta-cyclodextrin inclusion compound and dextrin are added to make granules. The above technical scheme has the characteristics of sweating and relieving exterior symptoms, clearing away heat and detoxifying, good taste, less loss of effective ingredients, stable quality, safe auxiliary materials, and convenient administration, and is mainly used to treat exogenous fever in children.

[0004] With respect to the above-mentioned related technologies, the inventors believe that there are the following defects: when drying the paste, since the paste has a certain thickness, there is no subsequent process for detecting whether the paste is completely dried. If the paste is not completely dried, it will affect the subsequent crushing and screening process. Summary of the invention

[0005] In order to improve the problem of insufficient material drying affecting subsequent processes, the present application provides a pediatric Chaigui antipyretic granules and a preparation device and method thereof.

[0006] The present application provides a preparation device for the Xiaoer Chaigui Antipyretic Granules using the following technical solution:

[0007] A preparation device for Xiaoer Chaigui Antipyretic Granules, comprising a drying device and a detection device for detecting whether the material is completely dried;

[0008] The detection device includes a detection box, a testing mechanism for detecting the hardness of the surface of the material, and a testing mechanism for detecting the humidity inside the material;

[0009] The test mechanism includes a sampling component for extracting different positions of the material and a viewing component for detecting the moisture content of the material;

[0010] The sampling assembly includes a bracket movably arranged in the detection box, a support frame lifted and arranged on the bracket, and a plurality of sampling parts for sampling materials, and the plurality of sampling parts move to different positions of the material.

[0011] Optionally, the sampling part includes a plurality of sampling racks fixed on the supporting frame, a sampling plate lifted and lowered on the sampling rack, a sampling tube detachably arranged on the sampling plate, and a sealing member for sealing the sampling tube. The number of the sampling racks is set to an odd number and the sampling tube in the middle is located at the center of the material, and the bottom end of the sampling tube is opened.

[0012] Optionally, the blocking member includes a blocking tube, a blocking block lifted and lowered in the blocking tube, and a power member for controlling the lifting and lowering of the blocking block. The blocking tube is fixed on the sampling plate, and the blocking tube is detachably connected to the sampling tube. The blocking tube slides and is adapted to cause the blocking block to move from the sampling tube into the blocking tube when the sampling tube starts sampling.

[0013] Optionally, the viewing assembly includes a viewing box arranged in the detection box, a control unit for controlling the sealing in the viewing box, multiple heating boxes for heating materials in the sampling tubes, multiple condensation units for condensing water vapor and a regulating unit for controlling the humidity of the viewing box, the detection box is provided with a control port for transporting materials, the control unit includes a control panel for sealing the control port and a control member for controlling the reciprocating motion of the control panel, multiple heating boxes correspond to the multiple sampling tubes, the heating box is fixedly connected with a feed pipe, one end of the feed pipe is vertically arranged close to the sampling tube and the other end is arc-shaped arranged toward the heating box, the bottom wall of the heating box is fixedly connected with a heating ring, the cross-sectional circle where the arc position of the lower part of the feed pipe is located is arranged parallel to the bottom of the heating box, and the sampling tube moves from the feed pipe to between the heating rings on the heating box.

[0014] Optionally, the condensation part includes a condensation plate, a condensation box, and a monitoring group for monitoring whether condensed water is generated, and the condensation plate is arranged on the upper part of the condensation box, and the condensation plate is arranged at an angle.

[0015] Optionally, the monitoring group includes two winding rollers, two winding motors, multiple test papers, a color sensor and multiple winding ropes. Operating cavities for placing the winding rollers are provided on both sides of the condensation box close to the opening. The winding roller rotates in the operating cavity. The winding motor is used to control the rotation of the winding roller. Multiple winding ropes are spaced apart from multiple test papers. The length of the winding rope is not less than the opening size of the condensation box. The winding ropes at both ends are fixedly connected to the peripheral walls of the winding rollers, respectively. The color sensor is installed in any one of the operating cavities. The color sensor is electrically connected to a buzzer.

[0016] Optionally, the testing mechanism includes a test rack fixed in the detection box, a standard box slidably set on the test rack, a test box slidably set on the test rack, a test needle lifted and lowered on the test rack, a feeding part for applying gravity to the test needle, and a judgment part for judging whether the material is punctured; an electromagnet for adsorbing the test needle is fixedly connected to the test rack.

[0017] Optionally, the feeding part includes a base plate fixed on the top of the test needle, a gravity sensor fixed on the base plate, a feeding box installed on the gravity sensor, a water pump and a water pipe, the electromagnet adsorbs the base plate, the water pump is arranged in the condensation box, one end of the water pipe is connected to the output end of the water pump and the other end is connected to the feeding box.

[0018] The present application provides a method for preparing Chaigui Antipyretic Granules for Children using the following technical solution:

[0019] A method for preparing pediatric Chaigui antipyretic granules comprises the following steps:

[0020] S1. Crush cinnamon twig and bupleurum root into coarse powder, add 12 times the amount of water, heat to 80°C, soak for 1 hour, distill for 4 hours, add 10% sodium chloride to the distillate, refrigerate for 12 hours, separate the upper oil, add 4 times the amount of beta-cyclodextrin and 8 times the amount of water, grind in a colloid mill for 20 to 30 minutes, and take out the paste;

[0021] S2, drying the paste in an oven at 50°C-60°C, and checking to ensure that the moisture is completely dried, crushing and sieving for later use; filtering the distilled water, adding 5-6 times the amount of water to the residue and boiling for 0.5-1 hour, filtering, combining the filtrate with the distilled water for later use;

[0022] S3. Take Pueraria root, crush it into the coarsest powder, and use the percolation method under the extract and fluid extract, using 50% ethanol as the solvent, soak for 24 hours and then percolate, collect 8 times the percolate, recover ethanol under reduced pressure, and continue to concentrate to a relative density of about 1.25;

[0023] S4, take Scutellaria baicalensis and crush it into the coarsest powder, bag and decoct it, add water and decoct it three times, add 8 times the amount of water for the first time, decoct it for 1 hour, add 8 times the amount of water for the second and third times, decoct it for 0.5 hours, combine the decoctions, filter, add 10% hydrochloric acid to the filtrate at 80-85°C to adjust the pH to 1.5-2.0, keep it warm for 1 hour, let it stand for 24 hours, filter it through 200 mesh, add 6 times the amount of water to the precipitate, stir and dissolve it, adjust the pH to 7.0-7.5 with 40% sodium hydroxide, add an equal amount of ethanol, filter it through 200 mesh, adjust the pH of the filtrate to 2.0 with 10% hydrochloric acid, keep it warm at 60°C for 30 minutes, let it stand for 24 hours, filter it through 200 mesh, wash the precipitate with water until it is neutral, and obtain a crude extract of Scutellaria baicalensis;

[0024] S5, take white peony root, duckweed, cicada shell and add water to decoct twice, add 10 times the amount of water for the first time, extract for 1 hour, add 10 times the amount of water for the second time to extract for 0.5 hours, combine the decoction, filter, combine the filtrate with the cinnamon twig and bupleurum water extract, concentrate to a relative density of about 1.07-1.10, add ethanol to make the alcohol content reach 60%, refrigerate for 24 hours, filter, recover ethanol under reduced pressure, and continue to concentrate to a relative density of about 1.25-1.28;

[0025] S6, combining the concentrated solution after recovering ethanol through water extraction and alcohol precipitation with the concentrated solution of Pueraria root extract, adding Scutellaria baicalensis extract; taking the obtained thick paste, adding appropriate amount of sucrose, dextrin, beta-cyclodextrin inclusion compound and sweet orange essence, making a soft material, making granules, drying, and granulating, so as to obtain

[0026] The Chaigui Antipyretic Granules for Children provided in this application adopt the following technical solution:

[0027] A kind of pediatric Chaigui antipyretic granules is prepared by utilizing the preparation method of the pediatric Chaigui antipyretic granules.

[0028] In summary, the present application includes at least one of the following beneficial technical effects:

[0029] 1. Xiaoer Chaigui Antipyretic Granules have the characteristics of sweating and relieving exterior symptoms, clearing away heat and detoxifying, good taste, less loss of effective ingredients, stable quality, safe auxiliary materials, and easy to take. It is mainly used to treat exogenous fever in children;

[0030] 2. When the standard material is punctured, record the value on the gravity sensor. At this time, move the bottom plate to be adsorbed by the electromagnet, and then adjust the weight of the water in the feed box to be lower than the above value. In this embodiment, the value is set to be no more than 3g different from the above recorded value, and the setting of the weight in the feed box is completed; then move the test box to the bottom of the test needle, place the material to be tested in the test box, and then cut off the power to the electromagnet. The test needle moves to the position in contact with the material to be tested. If the material to be tested is not punctured, the judgment rod contacts the proximity switch, and the display light does not light up. If the test needle punctures the material, it proves that the surface hardness of the material is not enough, that is, the material is not dried, and the display light is on, and there is no need to perform subsequent drying detection on the inside of the material;

[0031] 3. When the sampling tube enters the arc end along the feeding tube, since the inner diameter of the feeding tube is larger than the outer diameter of the sampling tube, the sampling tube moves to the position between the heating rings, thereby completing the feeding of the sampling tube. At the initial position, the winding rope is placed between the openings of the condensation box, and when the sampling tube begins to be heated and dried, the condensation plate begins to condense the water vapor. At the same time, through the cooperation of the two winding motors, the test paper is moved to the bottom of the condensation plate. After drying for a period of time, the test paper is pulled into the operating chamber where the color sensor is located. The color sensor identifies whether the test paper changes color. If the test paper turns red when it encounters water, it proves that water vapor is generated, which proves that there must be water in one of the three sampling tubes, so the material needs to be dried again. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present application;

[0033] Figure 2 is a schematic diagram of a sampling unit in an embodiment of the present application;

[0034] Figure 3 yes Figure 1 Enlarged schematic diagram of part A.

[0035] 1. Test box; 2. Bracket; 3. Support frame; 4. Sampling rack; 5. Sampling plate; 6. Sampling tube; 7. Sealing tube; 8. Sealing block; 9. Power part; 10. Inspection box; 11. Heating box; 12. Control port; 13. Control board; 14. Control part; 15. Feeding pipe; 16. Heating ring; 17. Condensation box; 18. Condensation plate; 19. Winding roller; 20. Winding motor; 21. Test paper; 22. Color sensor; 23. Winding rope; 24. Buzzer; 25. Test rack; 26. Standard box; 27. Test box; 28. Test needle; 29. ​​Electromagnet; 30. Bottom plate; 31. Gravity sensor; 32. Feed box; 33. Water pump; 34. Water pipe; 35. Proximity switch; 36. Display light; 37. Judgment rod. DETAILED DESCRIPTION

[0036] The following is combined with Figure 1-3 This application is described in further detail. Embodiment 1

[0037] The present application embodiment discloses a preparation device for Xiaoer Chaigui Antipyretic Granules. Figure 1-Figure 3 A preparation device for pediatric Chaigui antipyretic granules includes a drying device and a detection device for detecting whether the material is dried. The drying device can be a drying box in this embodiment. The detection device includes a detection box 1, a testing mechanism for detecting the hardness of the surface of the material, and a testing mechanism for detecting the humidity inside the material; the testing mechanism first detects the hardness of the outer surface of the material. If there is a problem with the hardness of the outer surface of the material, that is, it is not dried thoroughly, there is no need to detect the humidity inside the material. The humidity needs to be detected only when the surface hardness of the material meets the standard.

[0038] Reference Figure 1-Figure 3 The test mechanism includes a sampling component for extracting different positions of the material and a viewing component for detecting the moisture content of the material; the sampling component includes a bracket 2 movably arranged in the detection box 1, a support frame 3 lifted and arranged on the bracket 2, and a plurality of sampling parts for sampling the material, and the plurality of sampling parts move to different positions of the material, and quantitative detection of the material in both horizontal and vertical directions is performed through different sampling parts. For example, two sampling parts sample the same horizontal plane of the material, and the remaining sampling part performs sampling detection on different vertical positions, so as to judge whether the humidity of different positions of the material meets the standard; the sampling part includes a plurality of sampling racks 4 fixed on the support frame 3, a sampling plate 5 lifted and arranged on the sampling rack 4, and a sampling tube detachably arranged on the sampling plate 5. 6 and a sealing member for sealing the sampling tube 6, the bracket 2 moves in the horizontal direction, the support frame 3 moves on the bracket 2 in the vertical direction, and the movement of the bracket 2 and the movement of the support frame 3 are both realized by electric push rods or cylinders, and the lifting of the sampling plate 5 is also realized by electric push rods or cylinders. In this embodiment, the number of sampling racks 4 is set to an odd number, and the sampling tube 6 located in the middle is located at the center of the material, and in this embodiment, the sampling tube 6 located in the middle samples the center of the material in both horizontal and vertical directions, and the sampling tubes 6 located on both sides, one of the sampling tubes 6 samples the same vertical direction as the sampling tube 6 in the center, and the other sampling detects different vertical directions, thereby maximizing the degree of all-round detection of whether the inside of the material is dried.

[0039] Reference Figure 1-Figure 3The bottom end of the sampling tube 6 is open, and the blocking member includes a blocking tube 7, a blocking block 8 lifted and lowered in the blocking tube 7, and a power member 9 for controlling the lifting and lowering of the blocking block 8. The blocking tube 7 is fixed on the sampling plate 5, and the blocking tube 7 is detachably connected to the sampling tube 6. The blocking tube 7 slides and is adapted to the blocking block 8 moving from the sampling tube 6 to the blocking tube 7 when the sampling tube 6 starts sampling. The upper end of the sampling tube 6 is also open, and the inner diameter of the blocking tube 7 is adapted to the inner diameter of the sampling tube 6. In addition, two fixing holes are arranged at the bottom of the blocking tube 7, and adsorption parts are fixedly connected in the fixing holes. The adsorption parts can be set as electromagnets in this embodiment. When the electromagnets are energized, the blocking tube 7 and the sampling tube 6 can be firmly connected. The bottom end of the blocking tube 7 is aligned with the top end of the sampling tube 6. The blocking block 8 is made of rubber material, and the power part 9 is set as an electric push rod or a cylinder. The output end of the power part 9 is fixedly connected to the blocking block 8. In the initial state, the sampling tube 6 is in When entering into the material, the sampling tube 6 enters into the material through the descending sampling plate 5, and when the sampling tube 6 moves to above the specified position, in this process, the blocking block 8 is located at the bottom opening of the sampling tube 6. Therefore, before moving to the specified position, the material will not enter the sampling tube 6, and when the sampling tube 6 moves to above the specified position, the power part 9 is controlled to move, and the blocking block 8 moves from the sampling tube 6 to the sampling tube 6, and the sampling plate 5 is continued to be controlled to move downward, and the material at the corresponding position begins to enter the sampling tube 6. Since the sampling plate 5 has an extrusion force on the material during the downward movement, the material is also in an extrusion state when entering the sampling tube 6. In this embodiment, the moisture content of the material will not be very high, so the material entering the sampling tube 6 is squeezed into the same shape as the sampling tube 6, and the material will not fall off from the sampling tube 6. After the sampling tube 6 completes the material collection, the support frame 3 can be controlled to move upward until all the sampling tubes 6 are pulled out of the material.

[0040] Reference Figure 1-Figure 3The inspection component includes an inspection box 10 arranged in the detection box 1, a control part for controlling the sealing in the inspection box 10, a plurality of heating boxes 11 for heating the material in the sampling tube 6, a plurality of condensation parts for condensing water vapor, and an adjustment part for controlling the humidity of the inspection box 10. The inspection component obtains condensed water by the water vapor generated by drying the material encountering the condensation device, and can judge whether there is undried moisture in the material. The detection box 1 is provided with two spaces, wherein the sampling tube 6 and the inspection box 10 are respectively located in the two spaces. The detection box 1 is provided with a control port 12 for moving the material. The control panel 13 includes a control panel 13 for blocking the control port 12 and a control member 14 for realizing the reciprocating motion of the control panel 13. When the control panel 13 moves the position of the control port 12, the cavity where the inspection box 10 is located can be closed. When the material sampling is completed, the control bracket 2 is controlled to move in the horizontal direction, and the bracket 2 drives the three sampling tubes 6 to pass through the control port 12 and move to the top of the corresponding inspection box 10.

[0041] The heating box 11 is fixedly connected with a feed tube 15, one end of the feed tube 15 close to the sampling tube 6 is vertically arranged and the other end is arranged in an arc shape toward the heating box 11, and a heating ring 16 is fixedly connected to the bottom wall of the heating box 11. An inner cavity is arranged at the bottom of the heating box 11, and a plurality of electric heating wires are fixedly installed in the inner cavity. The electric heating wires are used to heat and dry the material in the sampling tube 6. The heating ring 16 is made of a material with strong thermal conductivity, which is convenient for heating and drying the sampling tube 6, and can accelerate the drying effect of the material in the sampling tube 6. The cross-sectional circle where the arc position of the lower part of the feed tube 15 is located is parallel to the bottom of the heating box 11. The sampling tube 6 is set up, and moves from the discharge tube 15 to between the heating rings 16 on the heating box 11; when the bracket 2 moves to the corresponding space, the three sampling tubes 6 are vertically set and face the opening of the discharge tube 15, and after the control adsorption component is powered off, the blocking tube 7 is separated from the sampling tube 6, and the sampling tube 6 falls into the vertical end of the discharge tube 15, and when the sampling tube 6 enters the arc end along the discharge tube 15, since the inner diameter of the discharge tube 15 is larger than the outer diameter of the sampling tube 6, the sampling tube 6 gradually becomes a horizontally placed state until it moves to the position between the heating rings 16, thereby completing the discharge of the sampling tube 6.

[0042] The condensation part includes a condensation plate 18, a condensation box 17, and a monitoring group for monitoring whether condensed water is generated. The condensation plate 18 is arranged on the upper part of the condensation box 17. The condensation plate 18 is inclined. When the three heating boxes 11 start to heat the sampling tube 6, the water in the sampling tube 6 starts to evaporate. Because the space here is sealed under the action of the control board 13, when the water vapor encounters the condensation plate 18, the condensation plate 18 starts to condense, and the condensed water on the condensation plate 18 drips toward the condensation box 17, so as to collect the condensed water. The monitoring group includes two winding rollers 19, two winding motors 20, multiple test papers 21, a color sensor 22 and multiple winding ropes 23. Both sides of the condensation box 17 near the opening are provided with an operating cavity for placing the winding roller 19. The winding roller 19 rotates in the operating cavity. The winding motor 20 is used to control the rotation of the winding roller 19. The winding rope 23 and the multiple test papers 21 are intermittently arranged, that is, a test paper 21 is arranged between the two winding ropes 23. In this embodiment, the test paper 21 is cobalt chloride test paper 21, and the winding rope The length of the winding rope 23 is not less than the opening size of the condensation box 17, the winding ropes 23 at both ends are fixedly connected to the peripheral wall of the winding roller 19, the color sensor 22 is installed in any operation cavity, the color sensor 22 is electrically connected to the buzzer 24, and the color sensor 22 and the buzzer 24 are controlled and connected by the PLC controller; in the initial position, the winding rope 23 is placed between the openings of the condensation box 17, and when the sampling tube 6 is heated and dried, the condensation plate 18 starts to condense the water vapor, and at the same time, the Through the cooperation of the two winding motors 20, the test paper 21 is moved to the bottom of the condensation plate 18. After drying for a period of time, the test paper 21 is pulled into the operating chamber where the color sensor 22 is located. The color sensor 22 identifies whether the test paper 21 has changed color. If the test paper 21 turns red when it encounters water, it proves that water vapor is generated, which proves that there must be water in one of the three sampling tubes 6. Therefore, the material needs to be dried again. Of course, the sample in the sampling tube 6 can also be returned to avoid waste of resources.

[0043] Reference Figure 1-Figure 3 In this embodiment, an adjustment unit is also provided for controlling the humidity in the area where the viewing box 10 is located. The adjustment unit can adopt a fan and a humidity sensor in the prior art. The humidity sensor is used to monitor the humidity in the area where the viewing box 10 is located. If the humidity exceeds the set value when the control port 12 is closed, the fan needs to be turned on to ventilate the corresponding area until the humidity returns to the set value to prevent external factors from affecting the material drying test results.

[0044] The testing mechanism includes a testing frame 25 fixed in the testing box 1, a standard box 26 slidably arranged on the testing frame 25, a testing box 27 slidably arranged on the testing frame 25, a testing needle 28 lifted and lowered on the testing frame 25, a feeding part for applying gravity to the testing needle 28, and a judging part for judging whether the material is punctured. The testing frame 25 and the viewing box 10 are respectively located in two spaces. First, the material is placed in the testing box 1 for external surface hardness detection. First, in this embodiment, it is necessary to place the material after drying in the standard box 26. At this time, the weight is continuously added through the feeding part until the material is punctured by the testing needle 28. At this time, it is proved that the maximum load on the outer surface of the material after drying is this value. In this embodiment, it is sufficient to set it slightly smaller than this value. Then, the material to be tested is placed in the testing box 27, and the test needle 28 and the weight of the above-mentioned set value are used for detection, and then the judgment part is used for judgment. If the test needle 28 punctures the surface of the material at this time, it is proved that the surface of the material is not dried.

[0045] Reference Figure 1-Figure 3The feeding part includes a bottom plate 30 fixed on the top of the test needle 28, a gravity sensor 31 fixed on the bottom plate 30, a feeding box 32 installed on the gravity sensor 31, a water pump 33 and a water pipe 34. The test frame 25 is fixedly connected with an electromagnet 29 for adsorbing the test needle 28. The electromagnet 29 adsorbs the bottom plate 30. The water pump 33 is arranged in the condensation box 17. One end of the water pipe 34 is connected to the output end of the water pump 33 and the other end is connected to the feeding box 32. The movement of the standard box 26 and the test box 27 is realized by the electric push rod. Of course, the standard box 26 can also be connected to The test box 27 is fixedly connected. In the initial state, the electromagnet 29 adsorbs the bottom plate 30 and places the dried material in the standard box 26. At this time, the electromagnet 29 is powered off. The electromagnet 29 contacts the standard material under the action of gravity. At this time, water is continuously pumped into the feed box 32 through the water pump 33, and the gravity sensor 31 also starts to count the weight in the feed box 32. In this embodiment, the gravity sensor 31 controls the opening or closing of the water pump 33. The judgment part includes a judgment rod 37, a proximity switch 35, and a display light 36 electrically connected to the proximity switch 35. The switch 35 is fixed on the test frame 25, and the judgment rod 37 is fixedly connected to the side wall of the test needle 28. When the test needle 28 abuts against the material, the proximity switch 35 is ensured to be in contact with the judgment rod 37. If the material is punctured, the judgment rod 37 is separated from the proximity switch 35. At this time, the proximity switch 35 triggers the display light 36 to light up, proving that the material is punctured; when the standard material is punctured, the value on the gravity sensor 31 is recorded. At this time, the bottom plate 30 is moved to be adsorbed with the electromagnet 29, and then the weight of the water in the feed box 32 is adjusted to be lower than the above value. In this embodiment, it is set to a value higher than the above record. The difference between the recorded values ​​is no more than 3g, and the setting of the weight in the feeding box 32 is completed; then the test box 27 is moved to below the test needle 28, the material to be tested is placed in the test box 27, and then the electromagnet 29 is powered off, and the test needle 28 moves to a position in contact with the material to be tested. If the material to be tested is not punctured, the judgment rod 37 contacts the proximity switch 35, and the display light 36 does not light up. If the test needle 28 punctures the material, it proves that the surface hardness of the material is not enough, that is, the material is not dried, and the display light 36 lights up, then there is no need to perform subsequent drying detection on the inside of the material.

[0046] The implementation principle of the preparation device of the pediatric Chaigui antipyretic granules in the embodiment of the present application is as follows: when the standard material is punctured, the value on the gravity sensor 31 is recorded, and at this time, the bottom plate 30 is moved to be adsorbed with the electromagnet 29, and then the weight of the water in the feed box 32 is adjusted to be lower than the above value. In this embodiment, the value is set to be no more than 3g different from the above recorded value, and the setting work of the weight in the feed box 32 is completed; then the test box 27 is moved to below the test needle 28, and the material to be tested is placed in the test box 27, and then the electromagnet 29 is powered off, and the test needle 28 moves to a position abutting against the material to be tested. If the material to be tested is not punctured, the judgment rod 37 contacts the proximity switch 35, and the display light 36 does not light up. If the test needle 28 punctures the material, it proves that the surface hardness of the material is not enough, that is, the material is not dried, and the display light 36 lights up, and there is no need to perform subsequent drying detection on the inside of the material.

[0047] If the outer surface of the material is not punctured, it is necessary to conduct subsequent drying inspection on the inside of the material. The sampling tube 6 in the middle samples the center of the material in both horizontal and vertical directions, and the sampling tubes 6 on both sides, one of which samples in the same vertical direction as the sampling tube 6 in the center, and the other samples in different vertical directions, thereby conducting a full-scale inspection on whether the inside of the material is dried to the greatest extent. Before moving to the specified position, the material will not enter the sampling tube 6, and when the sampling tube 6 moves to the top of the specified position, the power part is controlled at this time. 9 moves, the blocking block 8 moves from the sampling tube 6 to the inside of the sampling tube 6, and the sampling plate 5 continues to be controlled to move downward, and the material at the corresponding position begins to enter the sampling tube 6. Since the sampling plate 5 has an extrusion force on the material during the downward movement, the material is also in an extrusion state when entering the sampling tube 6. In this embodiment, the water content of the material is not very high, so the material entering the sampling tube 6 is squeezed into the same shape as the sampling tube 6, and the material will not fall off from the sampling tube 6. After the sampling tube 6 completes the material extraction, the support frame 3 can be controlled to move upward until all the sampling tubes 6 are pulled out of the material.

[0048] When the sampling tube 6 enters the arc-shaped end along the feeding tube 15, since the inner diameter of the feeding tube 15 is larger than the outer diameter of the sampling tube 6, the sampling tube 6 moves to the position between the heating rings 16, thereby completing the feeding of the sampling tube 6. At the initial position, the winding rope 23 is placed between the openings of the condensation box 17, and when the sampling tube 6 begins to be heated and dried, the condensation plate 18 begins to condense water vapor. At the same time, through the cooperation of the two winding motors 20, the test paper 21 is moved to the bottom of the condensation plate 18. After drying for a period of time, the test paper 21 is pulled into the operating cavity where the color sensor 22 is located. The color sensor 22 identifies whether the test paper 21 changes color. If the test paper 21 turns red when it encounters water, it proves that water vapor is generated, which proves that there must be water in one of the three sampling tubes 6, so the material needs to be dried again. Embodiment 2

[0049] The present application example discloses a method for preparing Chaigui antipyretic granules for children. Figure 1 A method for preparing pediatric Chaigui antipyretic granules comprises the following steps:

[0050] S1. Crush cinnamon twig and bupleurum root into coarse powder, add 12 times the amount of water, heat to 80°C, soak for 1 hour, distill for 4 hours, add 10% sodium chloride to the distillate, refrigerate for 12 hours, separate the upper oil, add 4 times the amount of beta-cyclodextrin and 8 times the amount of water, grind in a colloid mill for 20 to 30 minutes, and take out the paste;

[0051] S2, the paste is placed in an oven at 50 ℃ -60 degrees to dry, and it is necessary to check to ensure that the moisture is completely dried, and then sieved for use after crushing; the distilled water is filtered, and the residue is boiled with 5-6 times the amount of water for 0.5-1 hour, filtered, and the filtrate is combined with the distilled water for use; in this embodiment, the hardness of the outer surface of the material is first tested by the test needle 28. If the material to be tested is not punctured, the judgment rod 37 is in contact with the proximity switch 35, and the display light 36 is not on. If the test needle 28 punctures the material, it proves that the surface hardness of the material is not enough, that is, the material is not dried, and the display light 36 is on, then there is no need to perform subsequent drying detection on the inside of the material; and if the test paper 21 turns red when it encounters water, it proves that water vapor is generated, and the material needs to be dried again.

[0052] S3. Take Pueraria root, crush it into the coarsest powder, and use the percolation method under the extract and fluid extract, using 50% ethanol as the solvent, soak for 24 hours and then percolate, collect 8 times the percolate, recover ethanol under reduced pressure, and continue to concentrate to a relative density of about 1.25;

[0053] S4, take Scutellaria baicalensis and crush it into the coarsest powder, bag and decoct it, add water and decoct it three times, add 8 times the amount of water for the first time, decoct it for 1 hour, add 8 times the amount of water for the second and third times, decoct it for 0.5 hours, combine the decoctions, filter, add 10% hydrochloric acid to the filtrate at 80-85°C to adjust the pH to 1.5-2.0, keep it warm for 1 hour, let it stand for 24 hours, filter it through 200 mesh, add 6 times the amount of water to the precipitate, stir and dissolve it, adjust the pH to 7.0-7.5 with 40% sodium hydroxide, add an equal amount of ethanol, filter it through 200 mesh, adjust the pH of the filtrate to 2.0 with 10% hydrochloric acid, keep it warm at 60°C for 30 minutes, let it stand for 24 hours, filter it through 200 mesh, wash the precipitate with water until it is neutral, and obtain a crude extract of Scutellaria baicalensis;

[0054] S5, take white peony root, duckweed, cicada shell and add water to decoct twice, add 10 times the amount of water for the first time, extract for 1 hour, add 10 times the amount of water for the second time to extract for 0.5 hours, combine the decoction, filter, combine the filtrate with the cinnamon twig and bupleurum water extract, concentrate to a relative density of about 1.07-1.10, add ethanol to make the alcohol content reach 60%, refrigerate for 24 hours, filter, recover ethanol under reduced pressure, and continue to concentrate to a relative density of about 1.25-1.28;

[0055] S6. Combine the concentrated solution after recovering ethanol through the water extraction and alcohol precipitation and the concentrated solution of Pueraria root extract, and add the scutellaria baicalensis extract; take the obtained thick paste, add appropriate amount of sucrose, dextrin, beta-cyclodextrin inclusion compound and sweet orange essence, make it into a soft material, make granules, dry and granulate to obtain the product. Embodiment 3

[0056] The present application example discloses a kind of Xiaoer Chaigui antipyretic granules. Figure 1 A kind of Chaigui antipyretic granules for children includes the following raw medicinal materials in parts by weight: 702 parts of bupleurum; 243 parts of cinnamon twig; 702 parts of kudzu root; 324 parts of scutellaria baicalensis; 243 parts of duckweed; 243 parts of white peony root; 243 parts of cicada shell; the weight ratio of the mixture of the above drugs and the auxiliary materials is: mixture of drugs: 447-608 parts of thick paste, 5-7 parts of betadextrin inclusion compound; auxiliary materials: 1755 parts of sucrose, 750 parts of dextrin, 4.05 parts of sweet orange essence. The Chaigui antipyretic granules for children made with the above ingredients have the characteristics of sweating and relieving exterior symptoms, clearing away heat and detoxifying, good taste, less loss of effective ingredients, stable quality, safe auxiliary materials, and easy to take. It is mainly used to treat exogenous fever in children.

[0057] The above are all preferred embodiments of the present application, and the protection scope of the present application is not limited thereto. Therefore, any equivalent changes made according to the structure, shape, and principle of the present application should be included in the protection scope of the present application.

Claims

1. A preparation device for Xiaoer Chaigui Antipyretic Granules, characterized in that: It includes a drying device and a detection device for detecting whether the material is completely dried; The detection device comprises a detection box (1), a testing mechanism for detecting the hardness of the surface of the material, and a testing mechanism for detecting the humidity inside the material; The test mechanism includes a sampling component for extracting different positions of the material and a viewing component for detecting the moisture content of the material; The sampling assembly comprises a support (2) movably arranged in the detection box (1), a support frame (3) lifted and arranged on the support (2), and a plurality of sampling parts for sampling materials, wherein the plurality of sampling parts move to different positions on the material.

2. The preparation device of the Xiaoer Chaigui Antipyretic Granules according to claim 1, characterized in that: The sampling portion comprises a plurality of sampling racks (4) fixed on the support frame (3), a sampling plate (5) lifted and arranged on the sampling rack (4), a sampling tube (6) detachably arranged on the sampling plate (5), and a blocking member for blocking the sampling tube (6), the number of the sampling racks (4) is set to an odd number and the sampling tube (6) located in the middle is located at the center of the material, and the bottom end of the sampling tube (6) is opened.

3. The preparation device of the Xiaoer Chaigui Antipyretic Granules according to claim 1, characterized in that: The blocking member comprises a blocking tube (7), a blocking block (8) which is lifted and lowered in the blocking tube (7), and a power member (9) for controlling the lifting and lowering of the blocking block (8); the blocking tube (7) is fixed on the sampling plate (5); the blocking tube (7) is detachably connected to the sampling tube (6); the blocking tube (7) is slidably adapted to move the blocking block (8) from the sampling tube (6) into the blocking tube (7) when the sampling tube (6) starts sampling.

4. The preparation device of the Xiaoer Chaigui Antipyretic Granules according to claim 1, characterized in that: The inspection assembly comprises an inspection box (10) arranged in the inspection box (1), a control unit for controlling the sealing of the inspection box (10), a plurality of heating boxes (11) for heating the material in the sampling tube (6), a plurality of condensation units for condensing water vapor, and a regulating unit for controlling the humidity of the inspection box (10); the inspection box (1) is provided with a control port (12) for transporting materials; the control unit comprises a control panel (13) for blocking the control port (12) and a control member (14) for controlling the reciprocating motion of the control panel (13). , a plurality of the heating boxes (11) correspond to the plurality of sampling tubes (6), the heating box (11) is fixedly connected with a feed tube (15), one end of the feed tube (15) close to the sampling tube (6) is vertically arranged and the other end is arc-shaped toward the heating box (11), a heating ring (16) is fixedly connected to the bottom wall of the heating box (11), the cross-sectional circle of the arc-shaped lower part of the feed tube (15) is arranged parallel to the bottom of the heating box (11), and the sampling tube (6) moves from the feed tube (15) to between the heating rings (16) on the heating box (11).

5. The preparation device of the Xiaoer Chaigui Antipyretic Granules according to claim 1, characterized in that: The condensation section comprises a condensation plate (18), a condensation box (17) and a monitoring group for monitoring whether condensed water is generated. The condensation plate (18) is arranged on the upper part of the condensation box (17), and the condensation plate (18) is arranged at an angle.

6. The preparation device of the Xiaoer Chaigui Antipyretic Granules according to claim 1, characterized in that: The monitoring group comprises two winding rollers (19), two winding motors (20), a plurality of test papers (21), a color sensor (22) and a plurality of winding ropes (23). The condensation box (17) is provided with operating chambers for placing the winding rollers (19) on both sides close to the opening. The winding rollers (19) rotate in the operating chambers. The winding motors (20) are used to control the rotation of the winding rollers (19). The plurality of winding ropes (23) and the plurality of test papers (21) are arranged at intervals. The length of the winding ropes (23) is not less than the opening size of the condensation box (17). The winding ropes (23) at both ends are fixedly connected to the peripheral walls of the winding rollers (19) respectively. The color sensor (22) is installed in any one of the operating chambers. The color sensor (22) is electrically connected to a buzzer (24).

7. The preparation device of the Xiaoer Chaigui Antipyretic Granules according to claim 1, characterized in that: The testing mechanism comprises a testing frame (25) fixed in the detection box (1), a standard box (26) slidably arranged on the testing frame (25), a testing box (27) slidably arranged on the testing frame (25), a testing needle (28) lifted and lowered on the testing frame (25), a feeding part for applying gravity to the testing needle (28), and a judging part for judging whether a material is punctured. The testing frame (25) is fixedly connected with an electromagnet (29) for adsorbing the testing needle (28).

8. The preparation device of the Xiaoer Chaigui Antipyretic Granules according to claim 1, characterized in that: The feeding part comprises a base plate (30) fixed on the top of the test needle (28), a gravity sensor (31) fixed on the base plate (30), a feeding box (32) installed on the gravity sensor (31), a water pump (33) and a water pipe (34); the electromagnet (29) adsorbs the base plate (30); the water pump (33) is arranged in the condensation box (17); one end of the water pipe (34) is connected to the output end of the water pump (33) and the other end is connected to the feeding box (32).

9. A method for preparing Chaigui antipyretic granules for children, based on the preparation device for Chaigui antipyretic granules for children according to any one of claims 1 to 8, characterized in that: The steps include: S1. Crush cinnamon twig and bupleurum root into coarse powder, add 12 times the amount of water, heat to 80°C, soak for 1 hour, distill for 4 hours, add 10% sodium chloride to the distillate, refrigerate for 12 hours, separate the upper oil, add 4 times the amount of beta-cyclodextrin and 8 times the amount of water, grind in a colloid mill for 20 to 30 minutes, and take out the paste; S2, drying the paste in an oven at 50°C-60°C, and checking to ensure that the moisture is completely dried, crushing and sieving for later use; filtering the distilled water, adding 5-6 times the amount of water to the residue and boiling for 0.5-1 hour, filtering, combining the filtrate with the distilled water for later use; S3. Take Pueraria root, crush it into the coarsest powder, and use the percolation method under the extract and fluid extract, using 50% ethanol as the solvent, soak for 24 hours and then percolate, collect 8 times the percolate, recover ethanol under reduced pressure, and continue to concentrate to a relative density of about 1.25; S4, take Scutellaria baicalensis and crush it into the coarsest powder, bag and decoct it, add water and decoct it three times, add 8 times the amount of water for the first time, decoct it for 1 hour, add 8 times the amount of water for the second and third times, decoct it for 0.5 hours, combine the decoctions, filter, add 10% hydrochloric acid to the filtrate at 80-85°C to adjust the pH to 1.5-2.0, keep it warm for 1 hour, let it stand for 24 hours, filter it through 200 mesh, add 6 times the amount of water to the precipitate, stir and dissolve it, adjust the pH to 7.0-7.5 with 40% sodium hydroxide, add an equal amount of ethanol, filter it through 200 mesh, adjust the pH of the filtrate to 2.0 with 10% hydrochloric acid, keep it warm at 60°C for 30 minutes, let it stand for 24 hours, filter it through 200 mesh, wash the precipitate with water until it is neutral, and obtain a crude extract of Scutellaria baicalensis; S5, take white peony root, duckweed, cicada shell and add water to decoct twice, add 10 times the amount of water for the first time, extract for 1 hour, add 10 times the amount of water for the second time to extract for 0.5 hours, combine the decoction, filter, combine the filtrate with the cinnamon twig and bupleurum water extract, concentrate to a relative density of about 1.07-1.10, add ethanol to make the alcohol content reach 60%, refrigerate for 24 hours, filter, recover ethanol under reduced pressure, and continue to concentrate to a relative density of about 1.25-1.28; S6. Combine the concentrated solution after recovering ethanol through the water extraction and alcohol precipitation and the concentrated solution of Pueraria root extract, and add the scutellaria baicalensis extract; take the obtained thick paste, add appropriate amount of sucrose, dextrin, beta-cyclodextrin inclusion compound and sweet orange essence, make it into a soft material, make granules, dry and granulate to obtain the product.

10. A kind of Chaigui antipyretic granules for children, characterized by: The granules are prepared by the preparation method of the pediatric Chaigui antipyretic granules described in claim 9.

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