Plasma separating device

Abstract

The plasma separation device comprises a first main cylinder, a second main cylinder and a separation assembly, the separation assembly comprises that the bottom end of the first main cylinder is detachably connected to a filter cone through a plurality of locking plates, the filter cone comprises a plurality of supporting plates, the supporting plates are connected through cell filter membranes, a supporting ring is arranged on the inner bottom wall of the second main cylinder, and the supporting ring is arranged on the inner bottom wall of the second main cylinder. A communicating groove is formed in the bottom end of the upper side of each supporting plate, a liquid outlet is formed in the outer side of the second main cylinder, and the lowest point of the liquid outlet is not higher than the lowest point of the communicating groove; the separation assembly can automatically separate plasma in blood and can guide the plasma out of the device in cooperation with other parts to reduce repeated labor of medical staff, the bearing force of a cell filter membrane can be balanced through the design of the device, the dead weight of the filter membrane and the liquid pressure are overlapped to filter the plasma, and the efficiency of the device is improved. The filter efficiency is improved while the service life of the filter membrane is prolonged.

Description

Technical Field

[0001] The present invention relates to the technical field of plasma separation, and more specifically, to a plasma separation device. Background Art

[0002] Plasma is an important component of blood. Its main function in the blood is to carry blood cells, substances needed to maintain human life activities and waste produced in the body. Blood tests are usually involved in medical examinations. The conventional separation method is to let the sampling tube stand and then centrifuge it, and absorb the supernatant in the sample to separate the plasma.

[0003] However, most existing separation devices separate plasma by taking the supernatant through a dropper after the blood sample is allowed to stand and centrifuged. This process is usually time-consuming and requires the inspector to perform repeated pipetting actions, resulting in low separation efficiency and easily delaying the diagnosis of the patient's condition. Summary of the invention

[0004] The present invention provides a plasma separation device to solve the problem that most of the prior art methods involve separating plasma by taking the supernatant through a dropper after the blood sample is allowed to stand and centrifuged, and this process is usually time-consuming and requires the inspector to perform repeated suction actions, resulting in low separation efficiency and easily delaying the diagnosis of the patient's condition.

[0005] In order to achieve the above object, the present invention provides the following technical solutions:

[0006] A plasma separation device comprises a first main cylinder, a second main cylinder and a separation assembly, wherein the separation assembly comprises the bottom end of the first main cylinder being detachably connected to a filter bucket via a plurality of locking plates, the filter bucket comprising a plurality of support plates, each of the support plates being connected via a cell filter membrane, a support ring being arranged on the inner bottom wall of the second main cylinder, the top end of the support ring being in contact with the bottom ends of all the support plates at the same time, a connecting groove being arranged at the upper bottom end of the support plate, and a liquid outlet being arranged on the outer side of the second main cylinder, the lowest point of the liquid outlet being no higher than the lowest point of the connecting groove.

[0007] Preferably, a guide hopper is connected to the top of the inner wall of the first main cylinder, a connecting pipe is connected to the bottom of the guide hopper, the bottom of the connecting pipe is simultaneously clamped with all the locking plates, a connecting cover is provided at the bottom of the outer wall of the first main cylinder, and the connecting cover is threadedly connected to the second main cylinder.

[0008] Preferably, a support assembly is provided at the bottom end of the second main cylinder, and the support assembly includes two groups of connecting blocks connected to the outer bottom wall of the second main cylinder, each group of the connecting blocks is hinged with a pair of supporting feet, the two supporting feet are staggered, and the supporting feet are provided with sliding grooves. The outer side of the second main cylinder is connected to a control rod through a telescopic rod, and the control rod is simultaneously inserted into the sliding grooves provided on the two pairs of supporting feet.

[0009] Preferably, a drainage rod is hingedly connected to the outer end of the liquid outlet, a slot is opened at the outer end of the liquid outlet, the drainage rod is clamped in the slot, a baffle is slidably clamped at the outer end of the liquid outlet, and the baffle is blocked outside the slot.

[0010] Preferably, an overflow groove is provided on the outside of the second main cylinder, and the opening height of the top of the overflow groove is higher than the highest height of the filter bucket. The support ring is provided with a drain port facing the overflow groove, and the drain port is connected with the overflow groove. A limit rod is provided on the sliding card at the top of the overflow groove, and a float is provided at the bottom end of the limit rod. A pressure sensor is connected to the outer wall of the second main cylinder, and the limit rod is aligned with the sensing end of the pressure sensor in the vertical direction.

[0011] Preferably, a first sealing ring is provided at the bottom end of the first main cylinder, the first sealing ring is clamped on the top end of the second main cylinder, a second sealing ring is provided at the bottom end of the connecting tube, and the second sealing ring is clamped on the top end of the filter bucket.

[0012] The principle and beneficial effects of this technical solution:

[0013] (1) The separation component provided in the present invention can automatically separate the plasma in the blood. At the same time, the cell filter membrane arranged obliquely on the filter bucket can balance the bearing force of the cell filter membrane, so that the blood flows through the cell filter membrane to the high side of the cell filter membrane, and the weight of the filter membrane and the liquid pressure are superimposed to filter the plasma, thereby increasing the service life of the filter membrane and improving the filtration efficiency.

[0014] (2) The support assembly provided in the present invention can lift the entire device so that the experimenters can use different containers to hold the plasma. When the device needs to be lifted, the telescopic rod is extended, and the control rod connected to one end of the telescopic rod moves downward and drives the two pairs of legs to rotate along the connecting block through the slide groove until the two pairs of legs lift the device to the specified height.

[0015] (3) The pressure sensor provided in the present invention can help the experimenter monitor the accumulation amount of blood cells in the second main cylinder in real time. When the liquid level accumulated in the second main cylinder reaches a certain height, the buoyancy of the liquid in the overflow tank will drive the float and the limit rod provided on the top thereof to move upward, and the limit rod will collide with and squeeze the sensing end of the pressure sensor. At this time, the pressure sensor will prompt the experimenter to stop adding blood samples and export some blood cells through the opening at the top of the overflow tank. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0017] Figure 2 It is a schematic diagram of the structure after the present invention is split;

[0018] Figure 3 for Figure 2 Schematic diagram of the enlarged structure of the A area in the middle;

[0019] Figure 4 It is a schematic diagram of the structure after cutting of the present invention;

[0020] Figure 5 for Figure 4 Schematic diagram of the enlarged structure of the middle B area;

[0021] The figure marks in the drawings of the specification include: 1. first main cylinder; 2. second main cylinder; 3. connecting groove; 4. slot; 5. drainage rod; 6. telescopic rod; 7. baffle; 8. liquid outlet; 9. connecting block; 10. support foot; 11. slide groove; 12. control rod; 13. guide bucket; 14. connecting cover; 15. connecting pipe; 16. pressure sensor; 17. limit rod; 18. float; 19. overflow groove; 20. drain port; 21. first sealing ring; 22. cell filter membrane; 23. locking plate; 24. second sealing ring; 25. filter bucket; 26. support plate; 27. support ring. DETAILED DESCRIPTION

[0022] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments:

[0023] Example:

[0024] like Figures 1 to 5 As shown, the present invention provides a plasma separation device, including a first main cylinder 1, a second main cylinder 2 and a separation component, the separation component includes a first main cylinder 1 whose bottom end is detachably connected to a filter bucket 25 through a plurality of locking plates 23, the filter bucket 25 includes a plurality of support plates 26, each of the support plates 26 is connected through a cell filter membrane 22, a support ring 27 is arranged on the inner bottom wall of the second main cylinder 2, the top of the support ring 27 is in contact with the bottom ends of all the support plates 26 at the same time, a connecting groove 3 is provided at the upper bottom end of the support plate 26, a liquid outlet 8 is provided on the outer side of the second main cylinder 2, and the lowest point of the liquid outlet 8 is not higher than the lowest point of the connecting groove 3.

[0025] like Figure 1 , Figure 4 and Figure 5 As shown, a guide hopper 13 is connected to the top of the inner wall of the first main tube 1, and a connecting pipe 15 is connected to the bottom of the guide hopper 13. The bottom end of the connecting pipe 15 is simultaneously engaged with all the locking plates 23. A connecting cover 14 is provided at the bottom end of the outer wall of the first main tube 1, and the connecting cover 14 is screwed to the second main tube 2.

[0026] like Figures 1 to 3As shown, a support assembly is provided at the bottom end of the second main tube 2, and the support assembly includes two groups of connecting blocks 9 connected to the outer bottom wall of the second main tube 2, each group of connecting blocks 9 is hinged with a pair of supporting legs 10, the two supporting legs 10 are staggered, and a slide groove 11 is provided on the supporting legs 10. The outer side of the second main tube 2 is connected to a control rod 12 through a telescopic rod 6, and the control rod 12 is simultaneously inserted into the slide grooves 11 provided on the two pairs of supporting legs 10.

[0027] The support assembly can lift the entire device so that experimenters can use different containers to hold plasma. When the device needs to be lifted, the telescopic rod 6 is extended, and the control rod 12 connected to one end of the telescopic rod 6 will move downward and drive the two pairs of legs 10 to rotate along the connecting block 9 through the slide groove 11 until the two pairs of legs 10 lift the device to a specified height.

[0028] like Figure 3 As shown, a drainage rod 5 is hingedly connected to the outer end of the liquid outlet 8, a card slot 4 is opened at the outer end of the liquid outlet 8, the drainage rod 5 is clamped in the card slot 4, and a baffle 7 is slidably clamped at the outer end of the liquid outlet 8, and the baffle 7 is blocked outside the card slot 4.

[0029] like Figure 1 and Figures 3 to 5 As shown, an overflow groove 19 is arranged on the outside of the second main cylinder 2, and the opening height of the top of the overflow groove 19 is higher than the highest height of the filter bucket 26. The support ring 7 is provided with a drain port 20 toward the overflow groove 19, and the drain port 20 is connected with the overflow groove 19. A limit rod 17 is provided on the top of the overflow groove 19 for sliding, and a float 18 is provided on the bottom end of the limit rod 17. A pressure sensor 16 is connected to the outer wall of the second main cylinder 2, and the limit rod 17 is aligned with the sensing end of the pressure sensor 16 in the vertical direction.

[0030] The pressure sensor 16 can help the experimenter monitor the accumulation amount of blood cells in the second main cylinder 2 in real time. Since the second main cylinder 2 is connected to the overflow tank 19 through the drain port 20, the liquid level in the second main cylinder 2 and the overflow tank 19 should be equal. When the liquid level accumulated in the second main cylinder 2 reaches a certain height, the buoyancy of the liquid in the overflow tank 19 will drive the float 18 and the limit rod 17 set at its top to move upward. The limit rod 17 will collide and squeeze the sensing end of the pressure sensor 16. At this time, the pressure sensor 16 will prompt the experimenter to stop adding blood samples and export some blood cells through the top opening of the overflow tank 19.

[0031] like Figure 1 and Figure 5 As shown, a first sealing ring 21 is provided at the bottom end of the first main tube 1, and the first sealing ring 21 is clamped on the top end of the second main tube 2. A second sealing ring 24 is provided at the bottom end of the connecting tube 15, and the second sealing ring 24 is clamped on the top end of the filter bucket 25.

[0032] The specific usage and function of this embodiment are as follows:

[0033] When the device is used for plasma separation, a blood sample is injected into the first main cylinder 1 through the guide funnel 13 connected to the top of the first main cylinder 1, and the blood sample will enter the filter funnel 25 along the connecting tube 15, and accumulate in the second main cylinder 2 connected to the bottom of the first main cylinder 1. When the blood sample liquid level contacts the cell filter membrane 22, the plasma will pass through the cell filter membrane 22 under pressure and enter the space outside the cell filter membrane 22. At the same time, since the plasma is lighter in the blood components, the plasma accumulated on the lower side will eventually move up and pass through the cell filter membrane 22 into the space between the second main cylinder 2 and the cell filter membrane 22, and the blood sample will accumulate in the second main cylinder 2 and the cell filter membrane 22. The obliquely arranged cell filter membrane 22 can balance the bearing force of the cell filter membrane 22, so that the blood flows through the cell filter membrane 22 to the high side of the cell filter membrane 22, and the weight of the filter membrane and the liquid pressure are superimposed to filter the plasma, thereby increasing the service life of the filter membrane and improving the filtering efficiency. The plasma passing through the cell filter membrane 22 will eventually flow to the liquid outlet 8 opened on the outside of the second main cylinder 2, and flow to the external storage container through the liquid outlet 8. When the sample is about to be filtered out, the plasma outflow rate decreases. In order to keep the plasma outflow smooth, the baffle 7 set on the outside of the card slot 4 can be opened at this time, and the drainage rod 5 can be turned to a suitable angle for drainage;

[0034] When the device needs to be cleaned or the filter bucket 25 needs to be replaced regularly, the first main cylinder 1 is directly rotated to separate it from the second main cylinder 2, and the filter bucket 25 is rotated in the horizontal direction to make the locking plate 23 at the top of the filter bucket 25 disengage from the current locking groove. At this time, the filter bucket 25 is removed downward, and the new filter bucket 25 is inserted into the bottom end of the connecting pipe 15 according to the position of the original filter bucket 25. By setting the first sealing ring 21 and the second sealing ring 24, the sealing performance of the detachable parts after reconnection can be guaranteed.

[0035] The above is only an embodiment of the present invention, and the common knowledge such as the known specific technical solutions and / or characteristics in the solution is not described in detail here. It should be pointed out that for those skilled in the art, without departing from the technical solution of the present invention, several modifications and improvements can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. A plasma separation device, characterized in that: The invention comprises a first main cylinder (1), a second main cylinder (2) and a separation component, wherein the bottom end of the first main cylinder (1) is detachably connected to a filter bucket (25) via a plurality of locking plates (23), the filter bucket (25) comprises a plurality of support plates (26), each of the support plates (26) is connected via a cell filter membrane (22), a support ring (27) is arranged on the inner bottom wall of the second main cylinder (2), the top end of the support ring (27) is in contact with the bottom ends of all the support plates (26) at the same time, a connecting groove (3) is provided at the upper bottom end of the support plate (26), and a liquid outlet (8) is provided on the outer side of the second main cylinder (2), the lowest point of the liquid outlet (8) is not higher than the lowest point of the connecting groove (3).

2. A plasma separation device according to claim 1, characterized in that: The top end of the inner wall of the first main cylinder (1) is connected to a flow guide hopper (13), the bottom end of the flow guide hopper (13) is connected to a connecting pipe (15), the bottom end of the connecting pipe (15) is simultaneously engaged with all the locking plates (23), and the bottom end of the outer wall of the first main cylinder (1) is provided with a connecting cover (14), and the connecting cover (14) is screwed to the second main cylinder (2).

3. A plasma separation device according to claim 2, characterized in that: A support assembly is provided at the bottom end of the second main cylinder (2), and the support assembly comprises two groups of connection blocks (9) connected to the outer bottom wall of the second main cylinder (2), each group of the connection blocks (9) is hinged with a pair of legs (10), the two legs (10) are arranged alternately, and a slide groove (11) is provided on the legs (10), and the outer side of the second main cylinder (2) is connected to a control rod (12) through a telescopic rod (6), and the control rod (12) is simultaneously inserted into the slide grooves (11) provided on the two pairs of legs (10).

4. A plasma separation device according to claim 3, characterized in that: The outer end of the liquid outlet (8) is hinged with a drainage rod (5), the outer end of the liquid outlet (8) is provided with a clamping groove (4), the drainage rod (5) is clamped in the clamping groove (4), and the outer end of the liquid outlet (8) is slidably clamped with a baffle (7), and the baffle (7) is blocked outside the clamping groove (4).

5. A plasma separation device according to claim 4, characterized in that: An overflow groove (19) is arranged on the outside of the second main cylinder (2), the top opening height of the overflow groove (19) is higher than the highest height of the filter bucket (26), the support ring (7) is provided with a discharge port (20) facing the overflow groove (19), the discharge port (20) is connected with the overflow groove (19), a limit rod (17) is slidably provided at the top of the overflow groove (19), a floating ball (18) is arranged at the bottom end of the limit rod (17), a pressure sensor (16) is connected to the outer wall of the second main cylinder (2), and the limit rod (17) is aligned with the sensing end of the pressure sensor (16) in the vertical direction.

6. A plasma separation device according to claim 5, characterized in that: A first sealing ring (21) is provided at the bottom end of the first main cylinder (1), and the first sealing ring (21) is clamped on the top end of the second main cylinder (2). A second sealing ring (24) is provided at the bottom end of the connecting pipe (15), and the second sealing ring (24) is clamped on the top end of the filter bucket (25).

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