Insecticidal composition and application thereof

Abstract

The invention belongs to the technical field of pesticide disinfestation, and discloses an insecticidal composition and application thereof, the insecticidal composition comprises an active component A and an active component B, the active ingredient A is a compound as shown in a formula I: # imgabs0; the active ingredient B is any one of tetratolfenpyrad, cyclaniliprole, cyantraniliprole, fluchlorantraniliprole, chlorantraniliprole and flubendiamide; the active ingredient A is a compound as shown in a formula I: # imgabs0; the active ingredient B is any one of tetratolfenpyrad, cyclaniliprole, cyantraniliprole, flubendiamide and flubendiamide; the mass ratio of the active component A to the active component B is (1: 45)-(45: 1). According to the insecticidal composition disclosed by the invention, compounds with different action mechanisms are reasonably compounded, so that a synergistic effect is achieved, the pest control effect can be improved, the pesticide application amount is reduced, the use frequency is reduced, and the use cost is reduced.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticide compounding, and specifically relates to an insecticide composition and an application thereof in preventing and controlling pests in agricultural or non-agricultural environments. Background Art

[0002] Diamide insecticides have been a hot topic in the field of insecticide research in recent years. They mainly act on the nicotinic acid receptors of insects. Their mechanism of action is novel, highly effective, and has no cross-resistance with traditional pesticides.

[0003] In recent years, the occurrence of various crop pests has shown a trend of increasing year by year, and the area of ​​occurrence has increased year by year, causing great harm to crops, resulting in crop yield reduction, increased agricultural production costs and other problems. In order to improve the control effect of pests, farmers increase the dosage of diamide insecticides or mix pesticides at will. This unscientific use of pesticides not only fails to achieve the synergistic effect, but also leads to waste of pesticides, excessive residues, environmental pollution, and pests' resistance to pesticides.

[0004] In view of the current situation that pests have developed resistance to diamide insecticides, resulting in an increase in pesticide use year by year, but the control effect is on a downward trend, screening out new high-efficiency, low-toxic, green and environmentally friendly control agents can provide a theoretical basis for the integrated control of pests. Therefore, this experiment selected the formula I compound and 6 diamide insecticides for reasonable compounding, measured its biological activity against a variety of pests indoors, and carried out corresponding field efficacy tests, aiming to screen agents and dosages with better control effects on target pests, which can provide scientific drug use guidance for the control of a variety of agricultural and non-agricultural pests. At the same time, it is of great significance to do a good job in the long-term and continuous control of pests and reduce crop damage. Summary of the invention

[0005] In order to solve the above problems existing in the prior art, the present invention provides an insecticide composition and its application. The insecticide composition has excellent control effects on various agricultural and non-agricultural pests, reduces the dosage of pesticides, and slows down the development of pest resistance.

[0006] In order to achieve the above objectives, the present invention adopts the following technical scheme: an insecticide composition, wherein the active ingredients of the insecticide composition include active ingredient A and active ingredient B, and the active ingredient A is a compound represented by formula I:

[0007] The active ingredient B is any one of tetrazobactam, cyclobenzapamide, cyantraniliprole, flubendiamide, chlorantraniliprole, and flubendiamide; the mass ratio of the active ingredient A to the active ingredient B is 1:45 to 45:1, or any value within the above numerical range.

[0008] Furthermore, the active ingredient B is tetrazobactam, and the mass ratio of the active ingredient A to the active ingredient B is 1:24 to 30:1, or any value within the above numerical range;

[0009] The active ingredient B is bromobendan, and the mass ratio of the active ingredient A to the active ingredient B is 1:32 to 30:1, or any value within the above numerical range;

[0010] The active ingredient B is cyantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:30 to 30:1, or any value within the above numerical range;

[0011] The active ingredient B is flufenac, and the mass ratio of the active ingredient A to the active ingredient B is 1:32 to 30:1, or any value within the above numerical range;

[0012] The active ingredient B is chlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:36 to 45:1, or any value within the above numerical range;

[0013] The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:25 to 32:1, or any value within the above numerical range;

[0014] Furthermore, the active ingredient B is tetrazobactam, and the mass ratio of the active ingredient A to the active ingredient B is 1:20 to 30:1, or any value within the above numerical range;

[0015] The active ingredient B is bromofenac, and the mass ratio of the active ingredient A to the active ingredient B is 1:24 to 20:1, or any value within the above numerical range;

[0016] The active ingredient B is cyantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:27 to 18:1, or any value within the above numerical range;

[0017] The active ingredient B is flufenac, and the mass ratio of the active ingredient A to the active ingredient B is 1:24 to 24:1, or any value within the above numerical range;

[0018] The active ingredient B is chlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:30 to 32:1, or any value within the above numerical range;

[0019] The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 24:1, or any value within the above numerical range.

[0020] Furthermore, the active ingredient B is tetrazobactam, and the mass ratio of the active ingredient A to the active ingredient B is 1:12 to 25:1, or any value within the above numerical range;

[0021] The active ingredient B is bromofenac, and the mass ratio of the active ingredient A to the active ingredient B is 1:12 to 10:1, or any value within the above numerical range;

[0022] The active ingredient B is cyantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:20 to 25:1, or any value within the above numerical range;

[0023] The active ingredient B is flufenac, and the mass ratio of the active ingredient A to the active ingredient B is 1:18 to 16:1, or any value within the above numerical range;

[0024] The active ingredient B is chlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:25 to 24:1, or any value within the above numerical range;

[0025] The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:10 to 14:1, or any value within the above numerical range.

[0026] Furthermore, in addition to the active ingredients, the insecticide composition also includes other pesticide-acceptable adjuvants, and the adjuvants are selected from one or more of dispersants, wetting agents, emulsifiers, stabilizers, antifreeze agents, defoaming agents, preservatives, thickeners, solvents, organic acids, and dispersion media.

[0027] Furthermore, the composition can be prepared into various dosage forms, including wettable powders, water-dispersible granules, suspensions, aqueous emulsions, suspension seed coatings, microcapsule suspensions, microcapsule suspension-suspension concentrates, emulsifiable concentrates, microemulsions, dispersible liquids or granules.

[0028] The invention also discloses the use of the insecticide composition for preventing and controlling agricultural or non-agricultural pests.

[0029] Furthermore, the pests are Lepidoptera, Hemiptera, Coleoptera, Thysanoptera, Diptera, and mites.

[0030] Furthermore, the pests are Lepidoptera, Thysanoptera, and Hemiptera pests;

[0031] In particular, the pesticide composition of the present invention has excellent control effects on diamondback moth, cotton bollworm, corn borer, corn armyworm, fall armyworm, beet armyworm, rice leaf folder, Spodoptera exigua, thrips and aphids.

[0032] The present invention also discloses a method for controlling invertebrate pests, comprising contacting the invertebrate pests or their environment with a biologically effective amount of the composition described above.

[0033] The invention also discloses a method for preventing and controlling insect pests in agriculture or non-agriculture, comprising applying the above composition to plants where the insect pests exist.

[0034] The beneficial effects of the present invention are as follows:

[0035] The present invention rationally compounds insecticide compounds with different action mechanisms, has a synergistic effect on a variety of pests, can significantly improve the pest control effect, expand the insecticide spectrum; while delaying the development of pest resistance, it reduces the amount of pesticide applied, reduces the number of pesticide applications, and reduces production costs. DETAILED DESCRIPTION

[0036] In order to make the technical solutions, objectives and advantages of the present invention more clearly understood, the present invention is described with the following specific embodiments, but the present invention can be implemented in various forms and should not be limited by the embodiments described herein.

[0037] Preparation Example:

[0038] Preparation Example 1: 24% Formula I compound·tetrazolyl pyrifos suspension (5:1)

[0039] Formula: 20% compound of formula I, 4% tetrazolyl thiamethoxam, 2% isomeric tridecanol polyoxyethylene ether, 4% styrenated phenol polyoxyethylene ether phosphate, 2% sodium polycarboxylate, 0.25% xanthan gum, 5% ethylene glycol, 1% sodium benzoate, 0.5% silicone oil, and deionized water to make up the balance;

[0040] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in a reactor in sequence, water is added to mix evenly, and the suspension product is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0041] Preparation Example 2: 28% Formula I compound·tetrazolylcarb water dispersible granules (25:3)

[0042] Formula: 25% compound of formula I, 3% tetrazolyl amide, 5% sodium lignin sulfonate, 2.5% lakai powder BX, 12% sodium polycarboxylate, 5% white sugar, and kaolin makes up the balance.

[0043] Preparation method: according to the formula ratio, the active ingredient is added to the carrier, and the surfactant and other functional additives are added thereto, mixed, and after air flow grinding, 10-25% of water is added, and then kneading, granulation, drying and sieving are carried out to obtain a water-dispersible granule product; or the ground powder is sprayed with water in a boiling granulator, granulated, dried, and then sieved to obtain a water-dispersible granule product.

[0044] Preparation Example 3: 33% Formula I compound·tetrazolylcarb wettable powder (1:10)

[0045] Formula: 3% compound of formula I, 30% tetrazolyl amide, 2% sodium dodecyl sulfate, 10% sodium lignin sulfonate, 2% naphthalene sulfonate formaldehyde condensate, 5% dispersant NNO, 5% white carbon black, and kaolin makes up the balance;

[0046] Preparation method: according to the formula composition, the active ingredients, dispersants, wetting agents and fillers are mixed, uniformly stirred in a stirring kettle, and pulverized and mixed uniformly for multiple times by a jet mill to prepare the wettable powder of the composition of the present invention.

[0047] Preparation Example 4: 18% Formula I compound·Cyclomethanil suspension (5:1)

[0048] Formula: 15% compound of formula I, 3% cyclobromofenamide, 3% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 4% fatty alcohol polyoxyethylene ether phosphate, 2% polyoxyethylene sorbitan monooleate, 1% sodium polycarboxylate, 1.5% magnesium aluminum silicate, 0.1% carboxyethyl cellulose, 0.5% isothiazolinone, 5% ethylene glycol, 0.5% silicone oil, and deionized water to make up the balance;

[0049] Preparation method: Same as Preparation Example 1.

[0050] Preparation Example 5: 26% Formula I compound·Cyclomethanil water dispersible granules (1:12)

[0051] Formula: 2% compound of formula I, 24% bromofenamide, 10% lignin sulfonate, 8% naphthalene sulfonate formaldehyde condensate, 2% sodium dodecyl sulfate, 5% white carbon black, 30% starch, and kaolin makes up the balance.

[0052] Preparation method: Same as Preparation Example 2.

[0053] Preparation Example 6: 25% Formula I compound·Cyclofenac wettable powder (3:2)

[0054] Formula: 15% compound of formula I, 10% cyclobromofenamide, 3% sodium dodecyl sulfate, 5% sodium lignin sulfonate, 6% sodium polynaphthaldehyde sulfonate, 5% kaolin, 8% white carbon black, and bentonite makes up the balance;

[0055] Preparation method: Same as Preparation Example 3.

[0056] Preparation Example 7: 16% Formula I compound·cyantraniliprole suspension (1:3)

[0057] Formula: 4% compound of formula I, 12% cyantraniliprole, 1% sodium lignin sulfonate, 1% naphthalene sulfonate formaldehyde condensate, 3% castor oil polyoxyethylene ether, 2% sodium alkyl polyoxyethylene ether sulfonate, 4% fatty alcohol polyoxyethylene ether phosphate, 0.25% xanthan gum, 1% magnesium aluminum silicate, 4% propylene glycol, 0.01% potassium benzisothiazolinone, 0.5% silicone oil, and deionized water to make up the balance;

[0058] Preparation method: Same as Preparation Example 1.

[0059] Preparation Example 8: 27% Formula I compound·cyantraniliprole water dispersible granules (8:1)

[0060] Formula: 24% compound of formula I, 3% cyantraniliprole, 8% naphthalenesulfonate formaldehyde condensate, 10% sodium lignin sulfonate, 3% sodium dodecyl sulfate, 8% ammonium sulfate, and starch makes up the balance;

[0061] Preparation method: Same as Preparation Example 2.

[0062] Preparation Example 9: 20% Formula I compound·cyantraniliprole dispersible oil suspension (1:9)

[0063] Formula: 2% compound of formula I, 18% cyantraniliprole, 2% lignin sulfonate, 10% tristyrylphenol polyoxyethylene ether polyoxypropylene ether, 2% castor oil polyoxyethylene ether, 2% calcium dodecylbenzene sulfonate, 0.5% silicon dioxide, 0.5% organic bentonite, 10% 200# solvent oil, and methyl oleate to make up the balance;

[0064] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in the reactor in sequence, oil is added and mixed evenly, and the dispersible oil suspension product is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0065] Preparation Example 10: 20% Formula I compound·flufenamid suspension (4:1)

[0066] Formula: 16% compound of formula I, 4% flufenac, 3% ethylene glycol oxyethylene polyoxypropylene ether, 2% phenethylphenol polyoxyethylene polyoxypropylene ether, 2% tristyrylphenol ethoxylate phosphate, 2% sodium salt of polycarboxylate, 1.5% magnesium aluminum silicate, 0.1% carboxyethyl cellulose, 1% potassium benzoate, 5% ethylene glycol, 0.5% silicone oil, and deionized water to make up the balance;

[0067] Preparation method: Same as Preparation Example 1.

[0068] Preparation Example 11: 3.25% Formula I compound·flufenamid aqueous emulsion (12:1)

[0069] Formula: 3% compound of formula I, 0.25% flufenac, 5% phenylethylphenol polyoxyethylene polyoxypropylene ether, 3% styrenephenol polyoxyethylene ether phosphate, 18% cyclohexanone, 12% acetophenone, 0.2% xanthan gum, 0.1% potassium benzisothiazolinone, 5% ethylene glycol, 2% urea, 0.5% sodium sorbate, 0.1% organosilicon defoamer, and deionized water to make up the balance;

[0070] Preparation method: According to the formula ratio, the active ingredient is dissolved in the solvent and an emulsifier is added to dissolve it into a uniform oil phase. Deionized water, antifreeze, etc. are mixed together to form a uniform water phase. Under high-speed shearing, the oil phase is added to the water phase. After shearing to a qualified particle size, a defoamer, a thickener, and a preservative are added and stirred evenly to form a well-dispersed water emulsion product.

[0071] Preparation Example 12: 3% Formula I compound·flufenamid emulsifiable concentrate (1:9)

[0072] Formula: 0.3% of compound of formula I, 2.7% of flufenac, 10% of acetophenone, 20% of EO / PO block copolymer, 8% of N-octylpyrrolidone, 1% of calcium dodecylbenzenesulfonate, 12% of cyclohexanone, and the balance is made up of xylene.

[0073] Preparation method: according to the formula ratio of the preparation example, the measured active ingredients, solvents and co-solvents are added into a mixing kettle and stirred to dissolve, then an emulsifier is added, and the balance is supplemented with the remaining solvent, and the mixture is stirred evenly in a stirring kettle, and the desired emulsifiable concentrate of the present invention is obtained after filtering.

[0074] Preparation Example 13: 18% Formula I compound·Chlorantraniliprole suspension (9:1)

[0075] Formula: 16.2% compound of formula I, 1.8% chlorantraniliprole, 1% glycerol fatty acid ester polyoxyethylene ether, 2% fatty alcohol polyoxyethylene ether sulfate, 4% tristyrylphenol ethoxylate phosphate, 2% triphenylphenol polyoxyethylene ether, 0.25% xanthan gum, 1% magnesium aluminum silicate, 5% propylene glycol, 0.2% potassium benzoate, 0.5% silicone oil, and deionized water to make up the balance;

[0076] Preparation method: Same as Preparation Example 1.

[0077] Preparation Example 14: 22% Formula I compound·Chlorantraniliprole water dispersible granules (1:10)

[0078] Formula: 2% compound of formula I, 20% chlorantraniliprole, 3% sodium dodecyl sulfate, 8% naphthalenesulfonate formaldehyde condensate, 5% sodium salt of polycarboxylate, 5% white sugar, and kaolin makes up the balance.

[0079] Preparation method: Same as Preparation Example 2.

[0080] Preparation Example 15: 13.5% Formula I compound·Chlorantraniliprole dispersible oil suspension (22:5)

[0081] Formula: 11% compound of formula I, 2.5% chlorantraniliprole, 4% fatty alcohol polyoxyethylene ether, 2% sorbitan polyoxyethylene ether, 2% calcium dodecylbenzene sulfonate, 9% castor oil polyoxyethylene ether, 1% sodium salt of polycarboxylic acid, 2% sodium alkyl polyoxyethylene ether sulfonate, 1% organic bentonite, 1% silicon dioxide, and soybean oil makes up the balance;

[0082] Preparation method: Same as Preparation Example 9.

[0083] Preparation Example 16: 20% Formula I compound·flubencarb suspension (9:1)

[0084] Formula: 18% compound of formula I, 2% flubendiamide, 2% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 3% castor oil polyoxyethylene ether, 3% tristyrylphenol ethoxylate phosphate, 1% sodium salt of polycarboxylate, 1.5% magnesium aluminum silicate, 0.1% carboxyethyl cellulose, 1% sodium benzoate, 5% glycerol, 0.5% silicone oil, and deionized water to make up the balance;

[0085] Preparation method: Same as Preparation Example 1.

[0086] Preparation Example 17: 32% Formula I compound·flubencarb water dispersible granules (3:1)

[0087] Formula: 24% compound of formula I, 8% flubendiamide, 8% sodium lignin sulfonate, 2% flavonoid powder BX, 10% naphthalene sulfonate formaldehyde condensate, 5% white sugar, and kaolin makes up the balance;

[0088] Preparation method: Same as Preparation Example 2.

[0089] Preparation Example 18: 30% Formula I compound·flubencarb wettable powder (1:5)

[0090] Formula: 5% compound of formula I, 25% flubendiamide, 5% sodium lignin sulfonate, 5% dispersant NNO, 2.5% opening powder BX, 5% white carbon black, and kaolin to make up the balance;

[0091] Preparation method: Same as Preparation Example 3.

[0092] Indoor toxicity assay example

[0093] Test targets: Diamondback moth, fall armyworm, Spodoptera litura, corn armyworm, cotton bollworm, thrips, and aphids;

[0094] Test agents: tetrazobactam, cyclofenac, cyantraniliprole, flufenac, chlorantraniliprole, flubendiamide, and the original drug of the compound of formula I.

[0095] 1. Lepidoptera pest test method: refer to the Pesticide Part 14: Leaf Dipping Method in the Agricultural Industry Standard of the People's Republic of China NY / T 1154.14-2008 "Guidelines for Indoor Bioassay Tests of Pesticides", and conduct toxicity tests on the third-instar larvae of Plutella xylostella, Fall Armyworm, Corn Armyworm, and Cotton Bollworm;

[0096] First, the test agent was prepared into 5 concentration gradients with a suitable solvent, and a series of mass ratios were set for the mixed agents, and the final mass concentrations were prepared according to different ratios. The appropriate leaf disc was immersed in the test agent solution for 10 seconds, then taken out and dried, placed in a petri dish containing moisturizing filter paper, and inoculated with test insects, with 20 heads per replicate. Each treatment was repeated 4 times, and a treatment without agent (including all organic solvents and emulsifiers) was set as a blank control.

[0097] 48 hours after treatment, check the mortality of the test insects and record the total number of insects and the number of dead insects. Use tweezers to touch the insect body lightly, and the lack of reaction is regarded as the standard of death.

[0098] 2. Determination method for Hemiptera and Thysanoptera pests: refer to the agricultural industry standard of the People's Republic of China NY / T1154.6-2006 "Guidelines for Indoor Bioassay Tests of Pesticides" Part 6: Insect Dipping Method, and conduct toxicity tests on cotton aphids (wingless adults) and rice thrips (adults).

[0099] First, the test agent was prepared into 5 concentration gradients with a suitable solvent, and the mixed agent was set to a series of proportions, and the final mass concentration was prepared according to different proportions. After the target insects were immersed in the corresponding solution for 5 seconds, the excess solution was absorbed with filter paper, and the test insects were transferred to normal conditions for feeding. Each treatment was repeated 4 times, and 20 insects were immersed in each repetition. A treatment without agent (including all organic solvents and emulsifiers) was set as a blank control.

[0100] The mortality of the test insects was investigated 48 hours after treatment, and the number of dead insects and the total number of insects were recorded.

[0101] The above test calculates the mortality rate of each treatment based on the survey data. Calculate according to the following formula:

[0102]

[0103] Where:

[0104] P——mortality rate, in percentage (%);

[0105] K——indicates the number of dead insects, in units of heads;

[0106] N——represents the total number of insects treated, in heads.

[0107]

[0108] Where:

[0109] P1——adjusted mortality rate, in percentage (%);

[0110] P t ——Treatment mortality rate, expressed as percentage (%);

[0111] P0——blank control mortality rate, in percentage (%).

[0112] If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made according to the correction mortality formula; if the control mortality rate is greater than 20%, the test needs to be repeated.

[0113] The DPS statistical analysis system was used to analyze the toxicity regression equation, correlation coefficient and LC 50 Value, to evaluate the activity of the test agent on the biological test material.

[0114] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0115]

[0116] Where:

[0117] ATI——Actual Toxicity Index of Mixture;

[0118] S——LC of standard pesticide 50 , the unit is milligrams per liter (mg / L);

[0119] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0120] TTI=TI A ×P A +TI B ×P B

[0121] Where:

[0122] TTI – Theoretical Toxicity Index of Mixtures;

[0123] TI A ——A: toxicity index of the agent;

[0124] P A——The percentage of agent A in the mixture, in percentage (%);

[0125] TI B ——Toxicity index of agent B;

[0126] P B ——The percentage of agent B in the mixture, in percentage (%).

[0127]

[0128] Where:

[0129] CTC – Co-toxicity coefficient;

[0130] ATI——Actual Toxicity Index of Mixture;

[0131] TTI - Theoretical Toxicity Index of Mixture.

[0132] According to Sun Yunpei's method, the co-toxicity coefficient of two drugs in different ratios was calculated. The co-toxicity coefficient of the compound CTC ≥ 120 showed a synergistic effect; CTC ≤ 80 showed an antagonistic effect; 80 < CTC < 120 showed an additive effect.

[0133] Indoor pesticide activity test for Plutella xylostella:

[0134] Example 1: In order to verify the control effect of different ratios of the compound of formula I and flubendiamide on the cabbage diamondback moth, the indoor toxicity of the compound of formula I and flubendiamide in different ratios on the diamondback moth was determined. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0135] Table 1 Indoor biological activity test results of different ratios of compound I and flubendiamide against Plutella xylostella

[0136]

[0137]

[0138] From the indoor test results (see Table 1), it can be seen that the mass ratio of the compound of formula I to flufenac is 1:32-30:1, and the co-toxicity coefficient to Plutella xylostella is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to flufenac is 1:24-24:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is obvious; the mass ratio of the compound of formula I to flufenac is 1:18-24:1, the co-toxicity coefficient is greater than 150, and the synergistic effect is significant.

[0139] Example 2: In order to verify the control effect of different ratios of the compound of formula I and flubendiamide on the cabbage diamondback moth, the indoor toxicity of different ratios of the compound of formula I and flubendiamide on the diamondback moth was determined. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0140] Table 2 Indoor biological activity test results of different ratios of the compound of formula I and flubendiamide against Plutella xylostella

[0141]

[0142] The results of the indoor tests (see Table 2) show that the mass ratio of the compound of formula I to flubendiamide is 1:25-32:1, and the co-toxicity coefficient to Plutella xylostella is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to flubendiamide is 1:15-24:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is obvious; the mass ratio of the compound of formula I to flubendiamide is 1:10-24:1, the co-toxicity coefficient is greater than 150, and the synergistic effect is significant.

[0143] Experiment on the activity determination of pesticides against corn armyworm in indoor room

[0144] Example 3: In order to verify the control effect of different ratios of the compound of formula I and bromofenamide on corn armyworm, indoor toxicity determination of different ratios of the compound of formula I and bromofenamide on corn armyworm was carried out. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0145] Table 3 Indoor biological activity test results of different ratios of compound I and cyclobromofenamide against corn armyworm

[0146]

[0147] The results of the indoor tests (see Table 3) show that the mass ratio of the compound of formula I to bromine fenpropidium is 1:32-30:1, and the co-toxicity coefficient to corn armyworm is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to bromine fenpropidium is 1:24-20:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is obvious; the mass ratio of the compound of formula I to bromine fenpropidium is 1:12-10:1, the co-toxicity coefficient is greater than 150, and the synergistic effect is significant.

[0148] Example 4: In order to verify the control effect of different ratios of the compound of formula I and cyantraniliprole on corn armyworm, indoor toxicity determination of different ratios of the compound of formula I and cyantraniliprole on corn armyworm was carried out. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0149] Table 4 Indoor biological activity test results of different ratios of the compound of formula I and cyantraniliprole against corn armyworm

[0150]

[0151] The results of the indoor tests (see Table 4) show that the mass ratio of the compound of formula I to cyantraniliprole is 1:28-30:1, and the co-toxicity coefficient to corn armyworm is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to cyantraniliprole is 1:22-24:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to cyantraniliprole is 1:18-16:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is significant.

[0152] Indoor test on the activity of pesticides against cotton bollworm

[0153] Example 5: In order to verify the control effect of different ratios of the compound of formula I and tetrazopyram on cotton bollworm, the indoor toxicity of different ratios of the compound of formula I and tetrazopyram on cotton bollworm was determined. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0154] Table 5 Indoor biological activity test results of different ratios of the compound of formula I and tetrazolyl thiocarb against cotton bollworm

[0155]

[0156] The results of the indoor tests (see Table 5) show that the mass ratio of the compound of formula I to tetrazolyl thiocarb is 1:20-30:1, and the co-toxicity coefficient to cotton bollworm is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to tetrazolyl thiocarb is 1:10-20:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to tetrazolyl thiocarb is 1:5-20:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is significant.

[0157] Example 6: In order to verify the control effect of different ratios of the compound of formula I and chlorantraniliprole on cotton bollworm, indoor toxicity determination of different ratios of the compound of formula I and chlorantraniliprole on cotton bollworm was carried out. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0158] Table 6 Indoor biological activity test results of different ratios of the compound of formula I and chlorantraniliprole against cotton bollworm

[0159]

[0160]

[0161] The results of the indoor tests (see Table 6) show that the mass ratio of the compound of formula I to chlorantraniliprole is 1:36-32:1, and the co-toxicity coefficient to cotton bollworm is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to chlorantraniliprole is 1:25-24:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is obvious; the mass ratio of the compound of formula I to chlorantraniliprole is 1:14-18:1, the co-toxicity coefficient is greater than 150, and the synergistic effect is significant.

[0162] Experiment on indoor activity determination of pesticides against fall armyworm

[0163] Example 7: In order to verify the control effect of different ratios of the compound of formula I and tetrazolyl thiocarb on fall armyworm, indoor toxicity determination of different ratios of the compound of formula I and tetrazolyl thiocarb on fall armyworm was carried out. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0164] Table 7 Indoor biological activity test results of different ratios of the compound of formula I and tetrazolyl thiocarb against fall armyworm

[0165]

[0166] The results of the indoor tests (see Table 7) show that the mass ratio of the compound of formula I to tetrazolyl thiocarb is 1:24-30:1, and the co-toxicity coefficient to the fall armyworm is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to tetrazolyl thiocarb is 1:24-25:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to tetrazolyl thiocarb is 1:12-20:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is significant.

[0167] Example 8: In order to verify the control effect of different ratios of the compound of formula I and chlorantraniliprole on fall armyworm, indoor toxicity determination of different ratios of the compound of formula I and chlorantraniliprole on fall armyworm was carried out. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0168] Table 8 Indoor biological activity test results of different ratios of the compound of formula I and chlorantraniliprole against fall armyworm

[0169]

[0170]

[0171] From the indoor test results (see Table 8), it can be seen that the mass ratio of the compound of formula I to chlorantraniliprole is 1:30-45:1, and the co-toxicity coefficient to the fall armyworm is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to chlorantraniliprole is 1:22-35:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to chlorantraniliprole is 1:15-20:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is significant.

[0172] Experiment on the activity of pesticides against rice thrips in the laboratory

[0173] Example 9: In order to verify the control effect of different ratios of the compound of formula I and cyantraniliprole on rice thrips, indoor toxicity determination of different ratios of the compound of formula I and cyantraniliprole on rice thrips was carried out. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0174] Table 9 Indoor biological activity test results of different ratios of the compound of formula I and cyantraniliprole against rice thrips

[0175]

[0176] The results of the indoor tests (see Table 9) show that the mass ratio of the compound of formula I to cyantraniliprole is 1:30-25:1, and the co-toxicity coefficient to rice thrips is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to cyantraniliprole is 1:20-20:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to cyantraniliprole is 1:10-10:1, the co-toxicity coefficient is greater than 150, and the synergistic effect is significant.

[0177] Indoor test on the activity of pesticides against cotton aphids

[0178] Example 10: In order to verify the control effect of different ratios of the compound of formula I and cyantraniliprole on cotton aphids, indoor toxicity determination of different ratios of the compound of formula I and cyantraniliprole on cotton aphids was carried out. The corresponding concentrations were prepared according to the mass ratios in the table, and indoor insecticidal tests were carried out. The test results are as follows:

[0179] Table 10 Indoor biological activity test results of different ratios of the compound of formula I and cyantraniliprole against cotton aphids

[0180]

[0181] The results of the indoor tests (see Table 10) show that the mass ratio of the compound of formula I to cyantraniliprole is 1:27-18:1, and the co-toxicity coefficient to cotton aphid is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to cyantraniliprole is 1:15-9:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is obvious; the mass ratio of the compound of formula I to cyantraniliprole is 1:9-9:1, the co-toxicity coefficient is greater than 150, and the synergistic effect is significant.

[0182] Field efficacy test

[0183] Example 11: Field efficacy test for controlling diamondback moth

[0184] The test was conducted in accordance with the Guidelines for Field Efficacy Tests of Pesticides (I) Part 13: Insecticides for Control of Lepidoptera Larvae on Cruciferous Vegetables

[0185] (GB / T17980.13-2000) is carried out.

[0186] Test location: Broccoli planting base in Wangtian Village, Helan County, Yinchuan City, Ningxia Hui Autonomous Region. The broccoli variety is "excellent cold resistance". The test site is flat and has a high level of management.

[0187] Experimental method: The experiment set up 14 treatments, each treatment was repeated 4 times, and the area of ​​each plot was 20m 2 At the beginning of the peak period of the diamondback moth larvae (1-2 years), use a backpack electric sprayer (PJB-16), a cone nozzle, a pressure of 0.41Mpa, a flow rate of about 0.78L / min, spray once, and add water of about 45L / 667m 2 To prevent the liquid from drifting, spray the pesticide alternately between each treatment.

[0188] In each plot, 10 broccoli plants were randomly fixed and marked, and the number of live larvae of different ages on the whole broccoli plants was investigated. The insect population base was investigated before pesticide application, and the number of residual insects on the fixed plants and crop safety were investigated 3 and 10 days after pesticide application.

[0189] Calculation method of drug efficacy:

[0190]

[0191]

[0192] Table 11 Results of field efficacy test on Plutella xylostella

[0193]

[0194] From the results of the field efficacy test, it can be seen that the insect population base was investigated 3 days after the application, and the control effect was calculated. It was found that the preparation example 10: 20% formula I compound·flufenamid suspension (4:1) 16g / hm 2 The best control effect was 92.06%. The insect population base was investigated 10 days after the application. The control effects of the treatment groups of Preparation Example 10: 20% Formula I compound·flubencarb suspension (4:1), Preparation Example 17: 32% Formula I compound·flubencarb water dispersible granules (3:1), Preparation Example 2: 28% Formula I compound·tetrazodone worm amide water dispersible granules (25:3) and Preparation Example 7: 16% Formula I compound·cyantraniliprole suspension (1:3) were all increased compared with 3 days after the application. Among them, Preparation Example 10: 20% Formula I compound·flubencarb suspension (4:1) and Preparation Example 17: 32% Formula I compound·flubencarb water dispersible granules (3:1) had the best control effects, reaching 95.40% and 93.51% respectively.

[0195] Safety investigation: During the field test, no pesticide damage occurred in any treatment group, and no adverse effects were found on the surrounding environment and other beneficial organisms in the test area, indicating that the test agents were safe for broccoli growth at the doses provided.

[0196] Example 12: Field efficacy test for controlling corn armyworm and fall armyworm

[0197] Test location: Dazhuangsi Village, Liuquanpu Town, Zhenping County, Henan Province. The soil in the test site is yellow loam with medium soil fertility. The growth and growth period of corn plants in the test site are consistent.

[0198] Experimental crops: corn (Qin Xin 1708).

[0199] Target of prevention and control: Fall armyworm and corn armyworm occur together, with fall armyworm being the main target.

[0200] Experimental design: There are 14 treatments in total, each treatment is repeated 4 times, and the area of ​​each plot is 50m 2 , arranged in random blocks. Different treatments, with protection rows left around four weeks.

[0201] Test method: The test was carried out in the corn trumpet stage, and the medicine was prepared by double dilution method. First, the medicine was diluted with 100mL of clean water, and then shaken thoroughly to make a mother solution. 2 Water consumption standard: first pour half of the water into the sprayer, then add the mother liquor, and then pour the other half of the water into the sprayer. Stir the liquid thoroughly and spray evenly. Use a backpack electric sprayer to spray the corn leaves, especially the heart leaves. To ensure uniform application and reduce errors caused by the application tools or the application personnel's operating level, all spraying operations are completed by an experienced person alone.

[0202] Survey time and method: A five-point sampling method was used, with 5 plants surveyed at each point and a total of 25 plants surveyed for each treatment. A total of 3 surveys were conducted during the entire trial period. The insect population base was surveyed before the drug was applied, and the number of live insects on the plants was surveyed and recorded 7 and 14 days after the drug was applied.

[0203] Calculation method of drug efficacy:

[0204]

[0205] Table 12 Results of field trials on efficacy of pesticides against corn armyworm and fall armyworm

[0206]

[0207] The results showed that the quick-acting and long-lasting effects of the compound preparations in controlling corn armyworm and fall armyworm were significantly better than those of the single-dose control agent. 7 days after application, the best control effect was 92.53% for the water dispersible granules of the compound of formula I·cyantraniliprole (8:1) in Preparation Example 8; 14 days after application, the control effect was 94.05% for the wet powder of the compound of formula I·25% cyantraniliprole (3:2) in Preparation Example 6.

[0208] Example 13: Field efficacy test for controlling rice thrips

[0209] Test location: The test is located in the rice fields of Kongxiang Village, Shuitian Township, Jishui County, Ji'an City, Jiangxi Province. The fertility of the test land is above average, and the cultivation and management conditions of all test plots are consistent.

[0210] Experimental design: The experiment set up 5 drug treatments and 1 blank control, and the area of ​​each experimental plot was 25m 2 Each treatment was repeated 4 times, and all experimental plots were arranged in random blocks, with ridges built between the plots.

[0211] Test method: Apply the pesticide once 10 days after rice transplanting. Prepare the solution from low concentration to high concentration according to the test design. Use 45kg / 667m 2 .

[0212] Survey method: Survey the insect population before spraying, and survey the number of live insects 3d, 7d, and 14d after spraying. Survey 10 points in each plot using the parallel jump method, with each point surveying 0.1m 2 , investigate the residual insect quantity, calculate the insect population reduction rate and correct the control effect.

[0213] Calculation method of drug efficacy:

[0214]

[0215] Table 13 Results of field efficacy test on control of rice thrips

[0216]

[0217] The results of the field efficacy test show that 3 days after application, the control effects of the three combined treatment groups of Preparation Example 7: 16% Formula I compound·cyantraniliprole suspension concentrate (1:3), Preparation Example 9: 20% Formula I compound·cyantraniliprole dispersible oil suspension concentrate (1:9), and Preparation Example 8: 27% Formula I compound·cyantraniliprole water-dispersible granules (8:1) were 88.82%, 85.50%, and 83.52%, respectively, which were higher than the control agents 25% Formula I compound wettable powder and 10% cyantraniliprole suspension; 7 days after application, the control effects of the three Formula I compound and cyantraniliprole combined treatment doses reached 90.35%, 89.30% and 86.64%, respectively; 14 days after application, the control effects of the three Formula I compound and cyantraniliprole combined treatment doses were 91.74%, 89.05% and 84.87%, respectively.

[0218] Example 14: Field test on efficacy of drugs for controlling wolfberry aphids

[0219] The test site is Xishagou Village, Keke Town, Wulan County, Haixi Prefecture, Qinghai Province. The soil type of the test site is sandy loam, the terrain is flat, the soil fertility of the test site is consistent, and the drainage and irrigation are good.

[0220] Experimental design: The experiment set up 6 treatments, each treatment was repeated 4 times, and the area of ​​each plot was 30m 2 , each plot was arranged in random blocks.

[0221] Test method: The test was carried out once during the green fruit stage of wolfberry, and the 3WBD-20L backpack electric sprayer was used for spraying. The test agents were all prepared on site, diluted by the double dilution method, and sprayed evenly until a small amount of water dripped from the leaves.

[0222] Survey method: Randomly survey 2 wolfberry trees in each plot, survey each tree in 5 directions: east, south, west, north, and center, randomly survey 5 branches, and record the number of live insects remaining on each branch 30 cm long from the top. Investigate the insect population base before applying the medicine, and investigate the number of live insects 3d and 7d after applying the medicine. Calculate the insect population reduction rate and control effect based on the survey results.

[0223] Calculation method of drug efficacy:

[0224]

[0225] The test results are as follows:

[0226] Table 14 Field test results of efficacy of controlling wolfberry cotton aphid

[0227]

[0228] The results of the field efficacy test show that the compound of formula I and cyantraniliprole have a good field control effect on wolfberry cotton aphid. Test agent preparation example 8: 27% compound of formula I·cyantraniliprole water dispersible granules (8:1), preparation example 9: 20% compound of formula I·cyantraniliprole dispersible oil suspension (1:9), preparation example 7: 16% compound of formula I·cyantraniliprole suspension (1:3) 3 treatments 35g / hm 2 3 days after application, the population of target pests was significantly reduced, with the population reduction rates of 83.89%, 88.14% and 90.73% respectively, and the control effects of 84.35%, 88.48% and 90.99% respectively, which were higher than the control agents 25% formula I compound wettable powder and 10% cyantraniliprole suspension. 7 days after application, the control effect of Preparation Example 7: 16% formula I compound·cyantraniliprole suspension (1:3) was the highest, at 94.5%.

[0229] Although the application describes specific embodiments in detail by means of examples, the disclosure of the application may adopt various modifications and alternative forms. However, it should be understood that the disclosure of the application is not limited to the disclosed specific forms. On the contrary, the disclosure of the application covers all modifications, equivalents and alternative forms within the scope of the disclosure of the application, and the scope of the application is limited by the attached claims and their legal equivalents.

Claims

1. An insecticidal composition, characterized in that: The active ingredients of the insecticide composition include active ingredient A and active ingredient B, and the active ingredient A is a compound represented by formula I: The active ingredient B is any one of tetrazobactam, cyclobencarb, cyantraniliprole, flubendiamide, chlorantraniliprole, and flubendiamide; the mass ratio of the active ingredient A to the active ingredient B is 1:45 to 45:

1.

2. The insecticidal composition according to claim 1, characterized in that The active ingredient B is tetrazobactam, and the mass ratio of the active ingredient A to the active ingredient B is 1:24 to 30:1; The active ingredient B is bromofenac, and the mass ratio of the active ingredient A to the active ingredient B is 1:32 to 30:1; The active ingredient B is cyantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:30 to 30:1; The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:32 to 30:1; The active ingredient B is chlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:36 to 45:1; The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:25 to 32:

1.

3. The insecticidal composition according to claim 2, characterized in that The active ingredient B is tetrazobactam, and the mass ratio of the active ingredient A to the active ingredient B is 1:20 to 30:1; The active ingredient B is bromofenac, and the mass ratio of the active ingredient A to the active ingredient B is 1:24 to 20:1; The active ingredient B is cyantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:27 to 18:1; The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:24 to 24:1; The active ingredient B is chlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:30 to 32:1; The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 24:

1.

4. The insecticidal composition according to claim 3, characterized in that The active ingredient B is tetrazobactam, and the mass ratio of the active ingredient A to the active ingredient B is 1:12 to 25:1; The active ingredient B is cyclobenzapamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:12 to 10:1; The active ingredient B is cyantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:20 to 25:1; The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:18 to 16:1; The active ingredient B is chlorfenapyr, and the mass ratio of the active ingredient A to the active ingredient B is 1:25 to 24:1; The active ingredient B is flubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:10 to 14:

1.

5. The insecticidal composition according to claim 1, characterized in that In addition to the active ingredients, the insecticide composition also includes other pesticide-acceptable adjuvants, which are selected from one or more of dispersants, wetting agents, emulsifiers, stabilizers, antifreeze agents, defoamers, preservatives, thickeners, solvents, organic acids, and dispersion media.

6. The insecticidal composition according to claim 1, characterized in that The composition can be prepared into various dosage forms, including wettable powder, water-dispersible granules, suspension, aqueous emulsion, suspension seed coating, microcapsule suspension, microcapsule suspension-suspension, emulsifiable concentrate, microemulsion, dispersible liquid or granule.

7. Use of the insecticidal composition according to any one of claims 1 to 6 for controlling agricultural or non-agricultural pests.

8. Use according to claim 7, characterized in that The pests are Lepidoptera, Hemiptera, Coleoptera, Thysanoptera, Diptera and mites.

9. A method for controlling invertebrate pests, characterized in that: It comprises contacting the invertebrate pest or its environment with a biologically effective amount of a composition as described above.

10. A method for controlling insect pests in agriculture or non-agriculture, characterized in that: The method comprises applying the composition according to any one of claims 1 to 6 to plants where pests exist.

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