Thrombus aspiration device and method

Abstract

The embodiment of the invention provides a thrombus aspiration device and method, and the thrombus aspiration device comprises a sheath tube; the supply tube penetrates through the sheath tube and is suitable for providing a passage for conveying a thrombus treatment medium; wherein the outer diameter of the supply tube is smaller than the inner diameter of the sheathing canal, and a gap channel is formed between the outer wall of the supply tube and the inner wall of the sheathing canal and is suitable for providing a channel for sucking thrombus. By adopting the technical scheme, thrombus can be removed.

Description

Technical Field

[0001] The embodiments of the present disclosure relate to the field of medical device technology, and in particular to a thrombus aspiration device and method. Background Art

[0002] Deep vein thrombosis (DVT) refers to the embolus formed by blood coagulation in the deep vein cavity. The thrombus attached to the vein wall will block the venous lumen, causing venous reflux obstruction, thereby causing pulmonary embolism, post-thrombotic syndrome and other problems.

[0003] Therefore, how to remove the blood clot has become a technical problem that needs to be solved urgently. Summary of the invention

[0004] In view of this, the embodiments of the present disclosure provide a thrombus aspiration device and method, which can remove thrombus.

[0005] In order to solve the above technical problems, the present disclosure provides a thrombus aspiration device, comprising:

[0006] Sheath;

[0007] A supply tube, the supply tube passes through the sheath tube and is suitable for providing a passage for delivering a thrombus treatment medium;

[0008] The outer diameter of the supply tube is smaller than the inner diameter of the sheath tube, and a gap passage is provided between the outer wall of the supply tube and the inner wall of the sheath tube, and the gap passage is suitable for providing a passage for aspirating thrombus.

[0009] Optionally, the supply tube is suitable for relative movement with the sheath tube; the relative movement mode of the supply tube and the sheath tube conforms to one or more of the following:

[0010] The supply tube is suitable for relative movement with the sheath tube along the axial direction of the sheath tube;

[0011] The supply tube is suitable for relative movement with the sheath tube along the radial direction of the sheath tube;

[0012] The supply tube is suitable for rotating relative to the sheath tube with its axis as the axis.

[0013] Optionally, the thrombus aspiration device further comprises:

[0014] A dredging part, the proximal end of which is connected to the distal end of the supply tube, and the distal end of the dredging part is suitable for puncturing and crushing thrombus.

[0015] Optionally, the connection method between the proximal end of the dredging portion and the distal end of the supply pipe complies with one or more of the following:

[0016] Threaded connection;

[0017] Bonding;

[0018] welding;

[0019] Plug in.

[0020] Optionally, the proximal end of the dredging portion blocks the distal end of the supply tube.

[0021] Optionally, the supply tube has a supply hole, which is opened on the tube wall of the supply tube, and the thrombus treatment medium is suitable for entering the gap passage through the supply hole.

[0022] Optionally, the supply hole is opened on the tube wall of the supply tube adjacent to the distal end of the supply tube.

[0023] Optionally, the outer wall of the dredging portion has a groove, and the groove extends spirally along the axial direction of the dredging portion.

[0024] Optionally, the thrombus aspiration device further comprises:

[0025] A sheath seat, the sheath seat being connected to the sheath tube;

[0026] The sheath seat has a first channel and a sealing member;

[0027] Wherein, the distal end port of the first channel is in communication with the sheath tube, and the supply tube passes through the first channel;

[0028] The sealing member is located in the first channel and is suitable for sealing a gap between an inner wall of the first channel and the supply pipe.

[0029] Optionally, the sheath seat further has a second channel, the second channel is connected to the first channel, and the connecting position is located on the inner wall of the first channel;

[0030] Wherein, the sealing member is located at an end of the communication position away from the sheath tube.

[0031] Optionally, the thrombus aspiration device further comprises:

[0032] A suction piece is connected to a port of the second channel away from the first channel and is suitable for communicating with the gap passage through the second channel.

[0033] Optionally, the thrombus aspiration device further comprises:

[0034] A supply member is connected to the proximal tube opening of the supply tube and is suitable for delivering a thrombus treatment medium to the supply tube.

[0035] In order to solve the above technical problems, the embodiment of the present disclosure provides a thrombus aspiration method, which is applied to a thrombus aspiration device, wherein the thrombus aspiration device comprises a sheath tube and a supply tube, wherein the supply tube passes through the sheath tube and is suitable for providing a passage for delivering a first thrombus treatment medium and a second thrombus treatment medium, wherein the outer diameter of the supply tube is smaller than the inner diameter of the sheath tube, and a gap passage is provided between the outer wall of the supply tube and the inner wall of the sheath tube, wherein the gap passage is suitable for providing a passage for aspirating the thrombus;

[0036] The thrombus aspiration method comprises:

[0037] delivering the first thrombus treatment medium to the supply tube, wherein the first thrombus treatment medium is suitable for dissolving thrombus;

[0038] Let it sit for a preset time;

[0039] The interstitial passage is aspirated to cause the thrombus to enter the interstitial passage.

[0040] Optionally, a second thrombus treating medium is delivered to the supply tube so that the second thrombus treating medium carries the thrombus into the interstitial passage.

[0041] Compared with the prior art, the technical solution of the embodiment of the present disclosure has the following advantages:

[0042] A sheathed supply tube and a sheath tube are provided, wherein the supply tube is used to provide a passage for delivering a thrombus treatment medium, and there is a gap between the inner wall of the sheath tube and the outer wall of the supply tube, and the gap is used to provide a passage for aspirating the thrombus; the thrombus treatment medium is first delivered to the supply tube so that the thrombus is dissolved by the thrombus treatment medium and the adhesion strength of the thrombus is reduced, and then the gap between the inner wall of the sheath tube and the outer wall of the supply tube is aspirated so that the thrombus enters the gap, thereby enabling the thrombus to be removed.

[0043] Furthermore, when the distal end of the supply tube is located in the thrombus of the blood vessel, the supply hole opened on the tube wall of the supply tube adjacent to the distal end of the supply tube can also be located in the thrombus of the blood vessel, and the thrombus treatment medium in the supply tube can be released inside the thrombus through the supply hole, which can reduce the difficulty of the thrombus detaching from the blood vessel wall and increase the probability of the thrombus detaching from the blood vessel wall.

[0044] Furthermore, by pushing and pulling the supply tube back and forth relative to the sheath along the axial direction of the sheath and rotating the supply tube around the axis of the supply tube, the dredging part can drive the thrombus in the sheath to move along the axial and circumferential directions of the sheath, thereby crushing the thrombus in the blood vessel and the thrombus blocked in the sheath under the control of the supply tube, so as to achieve the dredging of the thrombus blocked in the blood vessel and the sheath.

[0045] A first thrombus treatment medium is delivered to the supply tube and transported to the interior of the thrombus by the supply tube. The thrombus is left to rest for a preset time, and part of the thrombus is dissolved by the first thrombus treatment medium, making it less difficult for the thrombus to fall off the blood vessel wall. The gap between the outer wall of the supply tube and the inner wall of the sheath is suctioned, and the thrombus enters the gap under the influence of the surrounding liquid, thereby achieving the removal of the thrombus.

[0046] Furthermore, a second thrombus treatment medium is delivered to the supply tube. On the first hand, the second thrombus treatment medium can continuously flush the thrombus during the suction process, thereby accelerating the detachment of the thrombus from the blood vessel wall. On the second hand, the second thrombus treatment medium can replace part of the blood to carry the detached thrombus into the interstitial channel, thereby reducing the amount of blood suctioned outside the surgical target and reducing the amount of blood loss during the operation. On the third hand, the second thrombus treatment medium can continuously stabilize the intravascular pressure during the suction process, improve problems such as low blood pressure caused by the suction process, and thereby reduce the risk of surgery. BRIEF DESCRIPTION OF THE DRAWINGS

[0047] In order to more clearly illustrate the technical solutions of the embodiments of this specification, the drawings required for use in the embodiments of this specification or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this specification. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0048] Figure 1 is a schematic structural diagram of a thrombus aspiration device in an embodiment of the present disclosure;

[0049] Figure 2 yes Figure 1 A schematic cross-sectional structure diagram of a thrombus aspiration device is shown;

[0050] Figure 3 yes Figure 2 A partial enlarged view of part A is shown;

[0051] Figure 4 yes Figure 2 A partial enlarged view of part B is shown;

[0052] Figure 5 yes Figure 2 A partial enlarged view of part C is shown;

[0053] Figure 6 It is a flow chart of a thrombus aspiration method in an embodiment of the present disclosure.

[0054] Description of reference numerals:

[0055] Supply tube 100, dredging part 110, Luer connector 120, sheath tube 200, sheath seat 300, first part 310, second part 320, sealing member 330, stress diffusion tube 400;

[0056] Gap passage a, first channel b, second channel c, supply hole d. DETAILED DESCRIPTION

[0057] Deep vein thrombosis (DVT) refers to the abnormal coagulation of venous blood in the deep vein cavity, which adheres to the blood vessel wall, blocks the venous lumen, and causes venous reflux obstruction. If not treated promptly, in the acute phase, the thrombus may detach and embolize the pulmonary artery, causing fatal or non-fatal pulmonary embolism (PE). In the later stage, the thrombus fibrosis may form post-thrombotic syndrome (PTS), affecting the ability to live and work.

[0058] In a specific application scenario, for patients with acute DVT, negative pressure aspiration of the thrombus is generally used. Through simple operations, the acute thrombus can be quickly and efficiently sucked into the catheter.

[0059] However, for patients with subacute or chronic DVT, the thrombosis time is relatively long, the thrombus has become organized, and the thrombus and the venous wall are extensively adhered and fibrotic. Doctors need to perform multiple aspirations. As the number of aspirations increases, the amount of blood aspirated also increases, which will cause the patient to lose too much blood and increase the risk of surgery.

[0060] In order to solve the above technical problems, in the embodiment of the present disclosure, a sleeved supply tube and a sheath tube may be provided, wherein the supply tube is used to provide a passage for delivering a thrombus treatment medium, and there is a gap between the inner wall of the sheath tube and the outer wall of the supply tube, and the gap is used to provide a passage for aspirating the thrombus. With the above scheme, the thrombus treatment medium may be first delivered to the supply tube so that the thrombus is dissolved by the thrombus treatment medium and the adhesion strength of the thrombus is reduced, and then the gap between the inner wall of the sheath tube and the outer wall of the supply tube is aspirated so that the thrombus enters the gap, thereby achieving thrombus removal.

[0061] In order to make the above-mentioned objects, features and beneficial effects of the present disclosure more obvious and easy to understand, the specific embodiments of the present disclosure are described in detail below with reference to the accompanying drawings.

[0062] For ease of description and understanding, in the embodiments of this specification, the proximal end and the distal end are first described, wherein the "proximal end" refers to the end close to the operator during the embolism removal process, and the "distal end" refers to the end away from the operator during the embolism removal process.

[0063] Combined with reference Figures 1 to 5 ,in, Figure 1 is a schematic structural diagram of a thrombus aspiration device in an embodiment of the present disclosure, Figure 2 yes Figure 1 The cross-sectional structure diagram of the thrombus aspiration device is shown. Figure 3 yes Figure 2 A partial enlarged view of part A shown; Figure 4 yes Figure 2 A partial enlarged view of part B is shown; Figure 5 yes Figure 2 A partial enlarged view of section C is shown.

[0064] Continue to combine references Figures 1 to 5 The thrombus aspiration device may include: a supply tube 100 and a sheath tube 200 .

[0065] Among them, the supply tube 100 is used as a passage for conveying thrombus treatment medium, the sheath tube 200 is sleeved on the outside of the supply tube 100, the inner diameter of the sheath tube 200 is larger than the outer diameter of the supply tube 100, and there is a gap passage a between the inner wall of the sheath tube 200 and the outer wall of the supply tube 100, the gap passage a extends along the axial direction of the supply tube 100, and the gap passage a is used as a passage for aspirating thrombus.

[0066] In some embodiments, the thrombus aspiration device may further include: a sheath seat 300 , which is connected to the sheath tube 200 .

[0067] Specifically, the sheath seat 300 may have a first channel b, the proximal end of the sheath tube 200 is connected to the distal end of the first channel b, and the proximal end of the sheath tube 200 is located in the first channel b. In this way, the first channel b and the sheath tube 200 can be connected, so that the first channel b is connected to the gap passage a.

[0068] In a specific implementation, the connection between the proximal tube opening of the sheath tube 200 and the distal port of the first channel b can be realized in a variety of ways. For example, the proximal tube opening of the sheath tube 200 is threadedly matched with the distal port of the first channel b. For example, the proximal tube opening of the sheath tube 200 is plugged and matched with the distal port of the first channel b.

[0069] Furthermore, the thrombus aspiration device may also include: a stress diffusion tube 400 , which is sleeved on the outside of the junction of the sheath tube 200 and the sheath seat 300 , and contacts or connects with the outside of the sheath tube 200 and the sheath seat 300 .

[0070] Specifically, the thickness of the side wall of the distal end of the stress diffusion tube 400 is smaller than the thickness of the side wall of the proximal end of the stress diffusion tube 400 , which can reduce the stress of the sheath tube 200 at the junction.

[0071] In some embodiments, the sheath seat 300 can be slidably and sealingly fitted with the supply tube 100 .

[0072] Specifically, the sheath seat 300 may have a seal 330, which is located in the first channel b and is suitable for sealing the gap between the inner wall of the first channel b and the supply tube 100 to reduce the probability of substances in the first channel b escaping through the gap to the outside of the thrombus aspiration device.

[0073] Furthermore, the sealing member 330 is an elastic annular structure fixed on the inner wall of the first channel b, for example, a silicone ring.

[0074] In a specific application scenario, the seal 330 is bonded and fixed to the inner wall of the first channel b, the outer wall of the seal 330 is sealed with the inner wall of the first channel b, the supply pipe 100 passes through the seal 330, and the inner wall of the seal 330 is sealed with the supply pipe 100.

[0075] It should be noted that the sealing member 330 needs to have a suitable sealing strength so that the sealing member 330 and the supply pipe 100 can slide relative to each other.

[0076] In a specific application scenario, the sheath seat 300 has a first part 310 and a second part 320, a first channel b is formed in the first part 310 and the second part 320, the proximal end of the first part 310 has a groove (not shown), the distal end of the second part 320 is located in the groove and is threadedly matched with the groove, the second part 320 can move relative to the second part 320 along the axial direction of the first channel b, the seal 330 is clamped between the bottom surface of the groove and the distal end surface of the second part 320, and the supply tube 100 passes through the seal 330.

[0077] By adjusting the distance between the bottom surface of the groove and the distal end surface of the second part 320, the seal 330 clamped between the bottom surface of the groove and the distal end surface of the second part 320 is deformed under extrusion, thereby changing the sealing strength and the difficulty of sliding fit between the seal 330 and the supply pipe 100.

[0078] In some embodiments, the sheath seat 300 may further have a second channel c, the second channel c is connected to the first channel b, and the connecting position between the second channel c and the first channel b is located on the inner wall of the first channel b.

[0079] In some embodiments, a “B” shape is formed between the second channel c and the first channel b.

[0080] In some embodiments, along the axial direction of the first channel b, the seal 330 is located in the first channel b at an end away from the sheath tube 200 at the communication position between the second channel c and the first channel b.

[0081] In some embodiments, the thrombus aspiration device may further include: a supply member (not shown), which is connected to the proximal end of the supply tube 100. The supply member is used to deliver the thrombus treatment medium to the supply tube 100, so as to deliver the thrombus treatment medium into the blood vessel through the supply tube 100.

[0082] In some embodiments, a Luer connector 120 is disposed at the proximal end of the supply tube 100 , and the supply member is connected to the proximal end of the supply tube 100 via the Luer connector 120 .

[0083] In some embodiments, the thrombus treating medium may be in a liquid state.

[0084] In some embodiments, the supply component may include a first liquid storage chamber (not shown), which is used to store the thrombus treatment medium and is connected to the supply tube 100 .

[0085] In a specific application scenario, the first liquid storage chamber may be a syringe having a push rod, and the thrombus treatment medium may be manually delivered into the supply tube 100 .

[0086] Furthermore, the supply component may also include a liquid supply pump (not shown), which is suitable for delivering the thrombus treatment medium in the first liquid storage chamber to the supply tube 100 .

[0087] In some embodiments, the liquid supply pump may include multiple types. For example, it may be a vacuum pump, which is respectively connected to the first liquid storage chamber and the supply tube 100, and the first liquid storage chamber and the supply tube 100 are connected through the vacuum pump. For example, it may be a peristaltic pump, and the supply member further includes a first connecting tube (not shown), the peristaltic pump is disposed on the first connecting tube, and both ends of the first connecting tube are respectively connected to the first liquid storage chamber and the supply tube 100, and the first liquid storage chamber and the supply tube 100 are connected through the first connecting tube.

[0088] It should be noted that the thrombus treatment medium refers to a medium for treating thrombus, wherein when the thrombus treatment medium is used to treat thrombus, a suitable thrombus treatment method can be selected according to the type of thrombus treatment medium. For example, the thrombus treatment medium can be a thrombolytic agent, which can reduce the difficulty of thrombus detachment from the blood vessel wall by dissolving the thrombus. For example, the thrombus treatment medium can be saline, which can increase the probability of thrombus detachment from the blood vessel wall by pressurizing the thrombus.

[0089] In some embodiments, the number of supply members may be multiple, and the first liquid storage chamber of at least one supply member among the multiple supply members stores a different type of thrombus treatment medium from the first liquid storage chambers of other supply members. For example, the number of first liquid storage chambers is two, and both first liquid storage chambers are connected to the supply tube 100. The two first liquid storage chambers store different types of thrombus treatment media, which are suitable for respectively delivering different thrombus treatment media to the supply tube 100.

[0090] In some embodiments, the thrombus aspiration device may further include: a suction piece (not shown), which is connected to the gap passage a and is used to provide negative pressure to aspirate the gap passage a to move the thrombus in the gap passage a out of the target body.

[0091] Specifically, the suction piece is connected to the end of the second channel c away from the first channel b. The second channel c, the first channel b, and the gap passage a are sequentially connected. When the suction piece suctions the second channel c, the thrombus in the gap passage a can be moved out of the treatment target body through the first channel b and the second channel c in sequence.

[0092] In some embodiments, the suction member may include a suction pump (not shown) and a second fluid storage chamber (not shown), the second fluid storage chamber is used to store thrombus, and the fluid supply pump is suitable for transporting the thrombus in the gap passage a into the second fluid storage chamber.

[0093] In some embodiments, the suction pump may include multiple types. For example, it may be a vacuum pump, which is respectively connected to the second liquid storage chamber and the second channel c, and the second liquid storage chamber and the second channel c are connected through the vacuum pump. For example, it may be a peristaltic pump, and the suction member may further include a second connecting tube (not shown), the peristaltic pump is disposed on the second connecting tube, and both ends of the second connecting tube are respectively connected to the second liquid storage chamber and the second channel c, and the second liquid storage chamber and the second channel c are connected through the second connecting tube.

[0094] In some embodiments, the sheath tube 200 is a tubular structure, and the tube wall of the sheath tube 200 can be a laminated structure formed by one or more layers of a lining layer, a hydrophilic coating, an anti-folding layer, a stiffness adjustment layer or a braided layer.

[0095] In a specific application scenario, the tube wall of the sheath tube 200 includes: an inner lining layer (not shown), an anti-folding layer (not shown), a braided layer (not shown), a stiffness adjustment layer (not shown) and a hydrophilic coating (not shown) which are sequentially stacked along the radial direction of the sheath tube 200, wherein the inner wall of the inner lining layer is the inner wall of the sheath tube 200, and the outer wall of the hydrophilic coating is the outer wall of the sheath tube 200.

[0096] Specifically, the material of the inner lining layer may include one or more polymer materials such as PTFE (Poly Tetra Fluoro Ethylene), ETFE (Ethylene Tetra Fluoro Ethylene), HDPE (High Density Poly Ethylene), or FEP (Fluorinated Ethylene Propylene), etc. This can reduce the friction force when the supply tube 100 moves in the sheath tube 200.

[0097] Specifically, the anti-bending layer can be a wire body with the axis of the sheath tube 200 as the axis, and is spirally wound and extended along the axial direction of the sheath tube 200 to form a spring-like structure. The material of the wire body can include one or more elastic memory materials such as stainless steel, nickel, titanium or nickel-titanium alloy. In this way, the anti-bending and anti-oval properties of the sheath tube 200 can be improved, and the sheath tube 200 can be restored to its original state after bending or extrusion.

[0098] Furthermore, the pitch of the anti-folding layer may be 0.1 to 0.5 mm.

[0099] Furthermore, the cross-sectional shape of the wire body may be circular or elliptical.

[0100] Specifically, the braided layer can be a mesh structure formed by braiding the wire body along the axis of the sheath tube 200, with the wire body being axially woven along the axis of the sheath tube 200. The wire body material can include one or more elastic memory materials such as stainless steel, nickel, titanium or nickel-titanium alloy. This can improve the anti-ovalization and anti-bending properties of the sheath tube 200, and can restore the original state after being squeezed or bent.

[0101] Specifically, the stiffness adjustment layer may have a plurality of sub-segments (not shown), and the hardness of the plurality of sub-segments gradually decreases along the axial direction of the sheath tube 200, wherein the hardness of the sub-segment adjacent to the distal end of the sheath tube 200 is less than the hardness of the sub-segment adjacent to the proximal end of the sheath tube 200. For example, the hardness of the sub-segment adjacent to the distal end of the sheath tube 200 is 50% of the hardness of the sub-segment adjacent to the proximal end of the sheath tube 200. In this way, the proximal end of the sheath tube 200 can maintain sufficient support strength and pushing strength while improving the bendable angle of the proximal end of the sheath tube 200. For example, along the direction away from the proximal end of the sheath tube 200 along the axis of the sheath tube 200, the bendable angle of the proximal end of the sheath tube 200 is 0 to 90 degrees.

[0102] Furthermore, the material of the sub-segment may include one or more materials such as Pebax, TPU (Thermo Plastic Urethane) or PA (Poly Amide).

[0103] In a specific implementation, the relationship between the material types of the multiple sub-segments may have various situations. For example, the materials of the multiple sub-segments are the same. In this case, different process parameters may be set when preparing each sub-segment, so that the hardness of the multiple sub-segments of the same material gradually decreases along the axial direction of the sheath tube 200. For example, the material of at least one sub-segment among the multiple sub-segments is different from that of the other sub-segments. In this case, different materials may be used when preparing each sub-segment, so that the hardness of the multiple sub-segments gradually decreases along the axial direction of the sheath tube 200.

[0104] Specifically, the material of the hydrophilic coating may include one or more hydrophilic materials such as Pro / Pel, Hydro-track, Hydro-coat or M-coatVR, etc. This can reduce the friction between the sheath tube 200 and the blood vessel wall and reduce the risk of surgery.

[0105] In some embodiments, the outer diameter of the sheath tube 200 may be 2 to 12 mm.

[0106] In some embodiments, the inner diameter of the sheath tube 200 may be 1.7 to 10 mm.

[0107] In some embodiments, the supply tube 100 is a tubular structure, and the material of the supply tube 100 may include one or more materials such as PTFE, ETFE, HDPE, FEP, stainless steel, nickel, titanium, or nickel-titanium alloy.

[0108] In some embodiments, the outer diameter of the supply tube 100 may be 0.1-1 mm.

[0109] In some embodiments, the ratio of the inner diameter of the sheath tube 200 to the outer diameter of the supply tube 100 is 2-50.

[0110] Specifically, the larger the ratio of the inner diameter of the sheath tube 200 to the outer diameter of the supply tube 100, the smaller the proportion of the supply tube 100 in the cross-section of the sheath tube 200, and the smaller the impact on the sheath tube 200 in aspirating thrombus; the smaller the ratio of the inner diameter of the sheath tube 200 to the outer diameter of the supply tube 100, the greater the structural strength of the supply tube 100, and the stronger the pushability of the supply tube 100.

[0111] In some embodiments, the supply pipe 100 has a supply hole d, and the supply hole d is opened on the pipe wall of the supply pipe 100 .

[0112] Specifically, the supply hole d is a through-hole structure opened on the tube wall of the supply tube 100. The thrombus treatment medium in the supply tube 100 can pass through the supply hole d through the side wall of the supply tube 100, leave the supply tube 100, enter the gap between the supply tube 100 and the sheath tube 200 and the blood vessel, and treat the thrombus.

[0113] In some embodiments, the diameter of the supply hole d may be 0.01-0.1 mm.

[0114] In some embodiments, the supply hole d is opened on the tube wall of the supply tube 100 adjacent to the distal end of the supply tube 100 .

[0115] Specifically, when the distal end of the supply tube 100 is located in the thrombus of the blood vessel, the supply hole d opened on the tube wall of the supply tube 100 adjacent to the distal end of the supply tube 100 can also be located in the thrombus of the blood vessel, and the thrombus treatment medium in the supply tube 100 can be released inside the thrombus through the supply hole d, which can reduce the difficulty of the thrombus detaching from the blood vessel wall and increase the probability of the thrombus detaching from the blood vessel wall.

[0116] In some embodiments, the supply hole d is opened on the tube wall of the supply tube 100 at a first position, wherein the first position refers to the portion of the supply tube 100 located in the sheath tube 200 during the suction process.

[0117] Specifically, during the suction process, the thrombus is likely to block the gap passage a. The supply hole d opened on the tube wall at the first position of the supply tube 100 is located at the gap passage a. The thrombus treatment medium in the supply tube 100 can be released inside the thrombus blocking the gap passage a through the supply hole d, thereby reducing the probability of blockage of the gap passage a.

[0118] In some embodiments, the number of supply holes d may be multiple, and the multiple supply holes d may have multiple distribution modes. For example, the multiple supply holes d may be distributed in variable diameters, wherein variable diameters refer to that the apertures of the multiple supply holes d may not be completely consistent. For example, the multiple supply holes d may be circumferentially distributed on the wall of the supply pipe 100. For example, the multiple supply holes d may be distributed on the wall of the supply pipe 100 at intervals along the axial direction of the supply pipe 100.

[0119] In some embodiments, the supply tube 100 can move relative to the sheath tube 200, and the supply tube 100 and the sheath tube 200 can achieve relative movement in a variety of ways. For example, the supply tube 100 can move relative to the sheath tube 200 along the axial direction of the sheath tube 200. For example, the supply tube 100 can move relative to the sheath tube 200 along the radial direction of the sheath tube 200. For example, the supply tube 100 can rotate relative to the sheath tube 200 with its axis as the axis.

[0120] In some embodiments, the thrombus aspiration device may further include a clearing portion 110 , which is connected to the supply tube 100 .

[0121] Specifically, the supply tube 100 is connected to the dredging portion 110 so that the dredging portion 110 can move synchronously with the supply tube 100 to puncture and crush the thrombus.

[0122] In a specific implementation, the connection between the dredging portion 110 and the supply pipe 100 can be realized in a variety of ways.

[0123] For example, the proximal end of the dredging portion 110 can be threadedly connected and fixed to the distal end of the supply pipe 100. For example, the proximal end of the dredging portion 110 can be adhesively fixed to the distal end of the supply pipe 100. For example, the proximal end of the dredging portion 110 can be welded and fixed to the distal end of the supply pipe 100. For example, the proximal end of the dredging portion 110 can be plugged and fixed to the distal end of the supply pipe 100.

[0124] In some embodiments, the proximal end of the clearing portion 110 blocks the distal end of the supply tube 100 .

[0125] In some embodiments, the dredging portion 110 has multiple implementations. For example, the outer wall of the dredging portion 110 has a groove, and the groove extends spirally along the axial direction of the dredging portion 110. For example, the dredging portion 110 is a cage-like structure or an umbrella-like structure with a cutting portion.

[0126] Specifically, by pushing and pulling the supply tube 100 back and forth relative to the sheath tube 200 along the axial direction of the sheath tube 200 and rotating the supply tube 100 around the axis of the supply tube 100, the dredging portion 110 can drive the thrombus in the sheath tube 200 to move along the axial direction and circumferential direction of the sheath tube 200, thereby crushing the thrombus in the blood vessel and the thrombus blocked in the sheath tube 200 under the control of the supply tube 100, so as to achieve the dredging of the thrombus blocked in the blood vessel and the sheath tube 200.

[0127] In some embodiments, the material of the dredging portion 110 may be a developing material such as platinum or tungsten. Platinum or tungsten has good opacity and can improve the visualization of the dredging portion 110 during the development and perspective process.

[0128] In the embodiment of the present disclosure, a thrombus aspiration method can also be provided. Figures 1 to 6 The thrombus aspiration method can be applied to a thrombus aspiration device, wherein the thrombus aspiration device has a sheath tube and a supply tube, the supply tube passes through the sheath tube, and is suitable for providing a passage for delivering a first thrombus treatment medium and a second thrombus treatment medium, the outer diameter of the supply tube is smaller than the inner diameter of the sheath tube, and the gap passage between the outer wall of the supply tube and the inner wall of the sheath tube is suitable for providing a passage for aspirating thrombus; the thrombus aspiration method may include steps S11 to S13:

[0129] Step S11: delivering a first thrombus treatment medium to the supply tube, wherein the first thrombus treatment medium is suitable for dissolving thrombus;

[0130] Step S12: let stand for a preset time;

[0131] Step S13: Suction the gap between the outer wall of the supply tube and the inner wall of the sheath tube to allow the thrombus to enter the gap.

[0132] Specifically, a first thrombus treatment medium is delivered to the supply tube, and the first thrombus treatment medium is delivered to the inside of the thrombus by the supply tube, and is left to rest for a preset time. Part of the thrombus is dissolved by the first thrombus treatment medium, and the difficulty of the thrombus falling off the blood vessel wall is reduced. The gap passage between the outer wall of the supply tube and the inner wall of the sheath tube is sucked, and the thrombus enters the gap passage under the influence of the surrounding liquid, thereby achieving the removal of the thrombus.

[0133] In some embodiments, the first thrombus treatment medium can be a thrombolytic agent, for example, pongasitide, dimethyl sulfate peptide, or benzene sulfonate.

[0134] In some embodiments, the delivery rate of the first thrombus treating medium may be 500-1000 ml / h.

[0135] In some embodiments, the preset time may be 30 to 60 minutes.

[0136] In some embodiments, the gap passage between the outer wall of the supply tube and the inner wall of the sheath tube can be continuously or indirectly sucked.

[0137] In some embodiments, while executing step S13 , a second thrombus treating medium is delivered to the supply tube, so that the second thrombus treating medium carries the thrombus into the interstitial passage.

[0138] Specifically, while executing step S13, the second thrombus treatment medium is delivered to the supply tube. On the one hand, the second thrombus treatment medium can continuously flush the thrombus during the suction process, thereby accelerating the detachment of the thrombus from the blood vessel wall; on the other hand, the second thrombus treatment medium can replace part of the blood to carry the detached thrombus into the interstitial channel, thereby reducing the amount of blood sucked outside the surgical target and reducing the amount of blood loss during the operation; on the third hand, the second thrombus treatment medium can continuously stabilize the intravascular pressure during the suction process, improve problems such as the decrease in blood pressure caused by the suction process, thereby reducing the risk of surgery.

[0139] It should be pointed out that in the process of converting the input medium from the first thrombus treatment medium to the second thrombus treatment medium, there is no need to replace the supply tube, and one tube can be used for two purposes, which can save operation time and cost.

[0140] In some embodiments, the second thrombus treating medium can be saline.

[0141] In some embodiments, the delivery rate of the second thrombus treating medium may be 100-500 ml / h.

[0142] In some embodiments, the thrombus aspiration method can be applied to the thrombus aspiration device in any of the aforementioned examples.

[0143] It should be noted that the principle, specific implementation and beneficial effects of the thrombus aspiration method can be found in the previous article and Figures 1 to 5 The relevant description about the thrombus aspiration device shown is not repeated here.

[0144] It is understandable that the term "and / or" in this article is only a description of the association relationship of the associated objects, indicating that there can be three relationships. For example, A and / or B can represent: A exists alone, A and B exist at the same time, and B exists alone. In addition, the character " / " in this article indicates that the associated objects before and after are in an "or" relationship.

[0145] It is understood that the "multiple" mentioned herein refers to two or more than two. The first, second, etc. descriptions in the embodiments of the present application are only used for illustration and distinction of the described objects, and have no order, nor do they represent any special limitation on the number of devices in the embodiments of the present application, and cannot constitute any limitation on the embodiments of the present application.

[0146] It can be understood that the above describes multiple embodiment schemes provided by the embodiments of the present disclosure, and the various optional methods introduced in each embodiment scheme can be combined and cross-referenced with each other without conflict, thereby extending a variety of possible embodiment schemes, which can all be considered as embodiment schemes disclosed and disclosed by the present disclosure.

[0147] Although the embodiments of the present disclosure are disclosed as above, the present disclosure is not limited thereto. Any person skilled in the art may make various changes and modifications without departing from the spirit and scope of the present disclosure. Therefore, the protection scope of the present disclosure shall be subject to the scope defined by the claims.

Claims

1. A thrombus aspiration device, characterized in that: include: Sheath; A supply tube, the supply tube passes through the sheath tube and is suitable for providing a passage for delivering a thrombus treatment medium; The outer diameter of the supply tube is smaller than the inner diameter of the sheath tube, and a gap passage is provided between the outer wall of the supply tube and the inner wall of the sheath tube, and the gap passage is suitable for providing a passage for aspirating thrombus.

2. The thrombus aspiration device according to claim 1, characterized in that: The supply tube is suitable for relative movement with the sheath tube; the relative movement mode between the supply tube and the sheath tube meets one or more of the following conditions: The supply tube is suitable for relative movement with the sheath tube along the axial direction of the sheath tube; The supply tube is suitable for relative movement with the sheath tube along the radial direction of the sheath tube; The supply tube is suitable for rotating relative to the sheath tube with its axis as the axis.

3. The thrombus aspiration device according to claim 2, characterized in that: Also includes: A dredging part, the proximal end of which is connected to the distal end of the supply tube, and the distal end of the dredging part is suitable for puncturing and crushing thrombus.

4. The thrombus aspiration device according to claim 3, characterized in that: The connection method between the proximal end of the dredging portion and the distal end of the supply pipe meets one or more of the following requirements: Threaded connection; Bonding; welding; Plug in.

5. The thrombus aspiration device according to claim 3, characterized in that: The proximal end of the dredging portion blocks the distal end of the supply pipe.

6. The thrombus aspiration device according to claim 3, characterized in that: The supply tube has a supply hole, which is opened on the tube wall of the supply tube, and the thrombus treatment medium is suitable for entering the gap passage through the supply hole.

7. The thrombus aspiration device according to claim 6, characterized in that: The supply hole is opened on the tube wall of the supply tube adjacent to the distal end of the supply tube.

8. The thrombus aspiration device according to claim 3, characterized in that: The outer wall of the dredging portion has a groove, and the groove extends spirally along the axial direction of the dredging portion.

9. The thrombus aspiration device according to claim 1, characterized in that: Also includes: A sheath seat, the sheath seat being connected to the sheath tube; The sheath seat has a first channel and a sealing member; Wherein, the distal end port of the first channel is in communication with the sheath tube, and the supply tube passes through the first channel; The sealing member is located in the first channel and is suitable for sealing a gap between an inner wall of the first channel and the supply pipe.

10. The thrombus aspiration device according to claim 9, characterized in that: The sheath seat also has a second channel, the second channel is connected to the first channel, and the connecting position is located on the inner wall of the first channel; Wherein, the sealing member is located at an end of the communication position away from the sheath tube.

11. The thrombus aspiration device according to claim 10, characterized in that: Also includes: A suction piece is connected to a port of the second channel away from the first channel and is suitable for communicating with the gap passage through the second channel.

12. The thrombus aspiration device according to claim 9, characterized in that: Also includes: A supply member is connected to the proximal tube opening of the supply tube and is suitable for delivering a thrombus treatment medium to the supply tube.

13. A method for aspirating thrombus, characterized in that: Applicable to a thrombus aspiration device, the thrombus aspiration device comprises a sheath tube and a supply tube, the supply tube passes through the sheath tube and is suitable for providing a passage for delivering a first thrombus treatment medium and a second thrombus treatment medium, the outer diameter of the supply tube is smaller than the inner diameter of the sheath tube, a gap passage is provided between the outer wall of the supply tube and the inner wall of the sheath tube, and the gap passage is suitable for providing a passage for aspirating thrombus; The method comprises: delivering the first thrombus treatment medium to the supply tube, wherein the first thrombus treatment medium is suitable for dissolving thrombus; Let it sit for a preset time; The interstitial passage is aspirated to cause the thrombus to enter the interstitial passage.

14. The method according to claim 13, characterized in that A second thrombus treating medium is delivered to the supply tube so that the second thrombus treating medium carries the thrombus into the interstitial passage.

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