Male erection-assisting delayed spray and preparation method thereof

Abstract

The invention provides a male erection-assisting delayed spray which is characterized by comprising the following components in parts by weight: 40-60 parts of a pepper fruit extract, 35-55 parts of a herba epimedii extract, 25-45 parts of a crocus sativus extract, 40-80 parts of a cynomorium songaricum extract, 30-50 parts of a lilac extract, 25-35 parts of a cistanche deserticola extract, 20-40 parts of a fructus cnidii extract and 25-45 parts of a honeysuckle extract. The spray prepared by the invention is mild in medicine property, safe to use, and good in assistant erection and antibacterial effect, and the extraction efficiency and quality of the spray are greatly improved.

Description

Technical Field

[0001] The invention belongs to the technical field of spray preparation, and specifically relates to a male erection-aiding and delayed-release spray and a preparation method thereof. Background Art

[0002] Male sexual dysfunction mainly refers to a disorder in a certain link of a man's sexual activity, which affects normal sexual function. It mainly includes: low libido or even no libido, erectile dysfunction, premature ejaculation, inability to ejaculate, no orgasm experience, etc. The treatment methods for male erectile dysfunction are mainly divided into oral Western medicine, oral Chinese medicine, Western medicine application and Chinese medicine application. However, oral Western medicine is prone to dependence, oral Chinese medicine is prone to affect the digestion and absorption of the spleen and stomach, Western medicine application will reduce the experience and pleasure of sexual life, and the extraction rate of effective ingredients of Chinese medicine application is not high, and the effect is not satisfactory.

[0003] Patent CN117338718A provides an external Chinese medicine erection spray for treating premature ejaculation and a preparation method thereof, which mainly includes Butea superba extract, Damiana leaf extract, Eurycoma longifolia extract, Cabinda bark extract, Maca extract, Epimedium extract, Purple Cloud flower extract, Allium sativum seed extract, Clove extract, Asarum extract, Galla chinensis extract, Morinda officinalis extract, Yohimbe hydrochloride aqueous solvent and other components. By extracting the effective ingredients of each Chinese medicine, it has a certain effect on the treatment of premature ejaculation, but there are as many as 13 raw materials and the preparation process is relatively complicated.

[0004] Most of the common drugs for treating premature ejaculation in the prior art have certain defects and poor preparation and extraction efficiency. Therefore, a male erection delay spray with safe medication and good effect is proposed. Summary of the invention

[0005] The purpose of the present invention is to provide a male erection-aiding and delaying spray and a preparation method thereof, which is compounded with Zanthoxylum bungeanum fruit extract, epimedium extract, saffron extract, Cynomorium songaricum extract, clove flower extract, Cistanche deserticola extract, Cnidium monnieri extract and Lonicera japonica extract as main raw materials. The preparation process has high extraction efficiency, the product has good erection-aiding and delaying effects, and has no effect on human safety.

[0006] In order to achieve the above object, the present invention provides the following technical solutions: A male erection-aiding and delaying spray comprises the following components in parts by weight: 40-60 parts of Zanthoxylum bungeanum fruit extract, 35-55 parts of epimedium extract, 25-45 parts of saffron extract, 40-80 parts of Cynomorium songaricum extract, 30-50 parts of clove flower extract, 25-35 parts of Cistanche deserticola extract, 20-40 parts of Cnidium monnieri extract, and 25-45 parts of Honeysuckle extract.

[0007] Preferably, the spray comprises the following components in parts by weight: 55 parts of Zanthoxylum bungeanum fruit extract, 40 parts of Epimedium extract, 35 parts of Crocus sativus extract, 65 parts of Cynomorium songaricum extract, 40 parts of Cistanche extract, 30 parts of Cistanche deserticola extract, 35 parts of Cnidium monnieri extract, and 40 parts of Honeysuckle extract.

[0008] The preparation method of the male erection-aiding and delaying spray comprises the following steps: S1: Mix 40-60 parts of Zanthoxylum bungeanum fruit extract, 25-45 parts of Crocus sativum extract, 40-80 parts of Cynomorium songaricum extract and 20-40 parts of Cnidium monnieri extract by weight, and stir and mix at a temperature of 50-70° C. for 40-60 minutes; S2: Add 35-55 parts of Epimedium extract and 25-35 parts of Cistanche extract to step S1, and stir and mix at a temperature of 80-100° C. for 30-50 minutes; S3: Add 30-50 parts of clove extract and 25-45 parts of honeysuckle extract to step S2, and stir and mix at a temperature of 40-60° C. for 1-3 hours to obtain the delayed spray.

[0009] Preferably, the preparation process of the Cynomorium songaricum extract in step S1 is as follows: ultrafinely crush the Cynomorium songaricum to obtain ultrafine Cynomorium songaricum powder; take 10-20 parts of ultrafine Cynomorium songaricum powder, 50-80 parts of water, 3-5 parts of chitosan and 0.2-0.4 parts of protease by weight, and stir the reaction at a temperature of 40-60°C for 1-2h; then heat it to 85-95°C, keep it warm for 10-20min, and then filter it through a 0.5-1um filter membrane to obtain the Cynomorium songaricum extract.

[0010] Preferably, the optimized preparation process of Cynomorium songaricum extract is as follows: ultrafinely grind Cynomorium songaricum to 500 mesh to obtain ultrafine Cynomorium songaricum powder; take 15 parts of ultrafine Cynomorium songaricum powder, 70 parts of water, 4 parts of chitosan and 0.35 parts of protease by weight, and stir the reaction at a temperature of 55°C for 1.5 hours; then heat to 92°C, keep warm for 16 minutes, and then filter through a 0.5-1um filter membrane to obtain the Cynomorium songaricum extract.

[0011] Preferably, the preparation process of the Cistanche extract in step S2 is as follows: take 15-25 parts of Cistanche powder by weight, add 60-100 parts of anhydrous ethanol solution thereto, and soak at 80-90°C for 4-6h; then increase the pressure to 1-3MPa, reflux and extract at a temperature of 105-120°C for 1-3h; after cooling to room temperature, add red Phaffia yeast, and ferment for 8-10h; then heat to boiling, cool, filter and obtain the filtrate to obtain the Cistanche extract.

[0012] Preferably, the optimized preparation process of the Cistanche deserticola extract is as follows: take 18 parts of 200-300 mesh Cistanche deserticola powder, add 80 parts of anhydrous ethanol solution thereto, and soak at 85°C for 5.5 hours; then increase the pressure to 2.5MPa, reflux and extract at a temperature of 110°C for 2 hours; after cooling to room temperature, add red Phaffia yeast, and ferment for 9 hours; then heat to boiling, cool and filter the filtrate to obtain the Cistanche deserticola extract.

[0013] Preferably, the preparation process of the honeysuckle extract in step S3 is as follows: take 10-20 parts of honeysuckle powder, 3-6 parts of cetyl ethylhexanoate, 25-35 parts of butylene glycol, and 20-40 parts of pentanediol by weight, and perform pulse treatment at a pulse intensity of 1-5KV / cm, a pulse width of 8-12μs, and a pulse number of 30-60; then perform ultrasonic treatment at a temperature of 30-50°C and a power of 50-80W for 30-60min; then centrifuge and filter, and collect the filtrate to obtain the honeysuckle extract.

[0014] Preferably, the optimized preparation process of honeysuckle extract is as follows: take 15 parts of honeysuckle powder, 5 parts of cetyl ethylhexanoate, 30 parts of butylene glycol, and 35 parts of pentanediol by weight, and perform pulse treatment at a pulse intensity of 3KV / cm, a pulse width of 10μs, and a pulse number of 40; then perform ultrasonic treatment at a temperature of 45°C and a power of 65W for 45 minutes; then centrifuge and filter, and collect the filtrate to obtain the honeysuckle extract.

[0015] Preferably, in step S1, the mixture is stirred and mixed at a rate of 800 r / min for 50 min at a temperature of 65°C; in step S2, the mixture is stirred and mixed at a rate of 600 r / min for 35 min at a temperature of 90°C; and in step S3, the mixture is stirred and mixed at a rate of 450 r / min for 2.5 h at a temperature of 55°C, to obtain the delayed spray.

[0016] Compared with the prior art, the advantages and beneficial effects of the present invention are: 1. The present invention uses Zanthoxylum bungeanum extract, Epimedium extract, Saffron extract, Cynomorium songaricum extract, Clove extract, Cistanche deserticola extract, Cnidium monnieri extract and Honeysuckle extract as main raw materials for compounding, and utilizes Epimedium extract, Cynomorium songaricum extract, Clove extract, Cistanche deserticola extract and Cnidium monnieri extract to warm the kidney and strengthen yang, invigorate essence and nourish tendons; meanwhile, Honeysuckle extract and Zanthoxylum bungeanum extract have the effects of clearing away heat and dampness, anti-inflammatory and disinfection; the spray has good effect of delaying erection, and is safe and has no side effects.

[0017] 2. In the preparation of the Cynomorium songaricum extract of the present invention, the mixing and stirring temperature is controlled to be 40-60°C to avoid oxidative decomposition of the effective ingredients at a higher temperature. The unique structure of chitosan is utilized to simultaneously extract water-soluble components and fat-soluble components, and the extraction efficiency and effect are better.

[0018] 3. In the preparation of the Cistanche deserticola extract, the present invention improves the extraction effect of the active ingredients in the Cistanche deserticola by adding Phaffia rhodozyma for fermentation, and the extract contains less irritating substances, does not irritate the skin, and has higher safety.

[0019] 4. In the preparation of the honeysuckle extract, the present invention adopts pulse electric field and ultrasonic synergistic treatment, which can achieve the extraction of high-content effective ingredients at low temperature and in a short time, avoid the influence of long-term thermal effect on heat-sensitive components, and improve the extraction efficiency. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0021] Example 1 This embodiment provides a method for preparing a male erection-promoting and delaying spray, comprising the following steps: S1: Crush Cynomorium songaricum to 200-500 mesh to obtain Cynomorium songaricum ultrafine powder; take 10g Cynomorium songaricum ultrafine powder, 50g water, 3g chitosan and 0.2g protease, stir and react at a temperature of 40°C at a rate of 500r / min for 1h; then heat to 85°C, keep warm for 10min, and filter through a 0.5-1um filter membrane to obtain Cynomorium songaricum extract; take 40g Zanthoxylum fruit extract, 25g saffron extract, 40g Cynomorium songaricum extract and 20g Cnidium monnieri extract, mix them, stir and mix at a temperature of 50°C at a rate of 800r / min for 40min to obtain mixed solution A; the protease is a neutral protease, 50U / mg, Hunan Yunbang Biotechnology Co., Ltd.

[0022] S2: Crush Cistanche deserticola to 300-500 mesh to obtain Cistanche deserticola powder; take 15g of Cistanche deserticola powder, add 60g of anhydrous ethanol solution thereto, and soak at 80°C for 4h; then increase the pressure to 1MPa, reflux and extract at 105°C for 1h; add red Phaffia yeast after cooling to room temperature, and ferment for 8h; heat to boiling again, cool and filter the filtrate to obtain Cistanche deserticola extract; add 35g of Epimedium extract and 25g of Cistanche deserticola extract to the mixed solution A in step S1, stir and mix at 80°C at a rate of 600r / min for 30min to obtain a mixed solution B; the red Phaffia yeast is from Nanjing Hegu Life Biotechnology Co., Ltd.

[0023] S3: crush honeysuckle to 200-300 mesh to obtain honeysuckle powder; take 20g honeysuckle powder, 6g cetyl ethylhexanoate, 35g butylene glycol, and 40g pentanediol, and perform pulse treatment at a pulse intensity of 1KV / cm, a pulse width of 8μs, and a pulse number of 30; then perform ultrasonic treatment for 30min at a temperature of 30°C and a power of 50W; then centrifuge and filter, collect the filtrate to obtain the honeysuckle extract; add 30g clove extract and 25g honeysuckle extract to the mixed solution of step S2, and stir and mix at a temperature of 40°C and a speed of 800r / min for 1h to obtain the delayed spray.

[0024] Example 2 This embodiment provides a method for preparing a male erection-promoting and delaying spray, comprising the following steps: S1: Crush Cynomorium songaricum to 200-500 mesh to obtain Cynomorium songaricum ultrafine powder; take 20g Cynomorium songaricum ultrafine powder, 80g water, 5g chitosan and 0.4g protease, stir and react at a temperature of 60°C at a rate of 500r / min for 2h; then heat to 95°C, keep warm for 20min, and filter through a 0.5-1um filter membrane to obtain Cynomorium songaricum extract; take 60g Zanthoxylum fruit extract, 45g saffron extract, 80g Cynomorium songaricum extract and 40g Cnidium monnieri extract, mix them, stir and mix at a temperature of 70°C at a rate of 800r / min for 60min to obtain mixed solution A; the protease is a neutral protease, 50U / mg, Hunan Yunbang Biotechnology Co., Ltd.

[0025] S2: Crush Cistanche deserticola to 300-500 mesh to obtain Cistanche deserticola powder; take 25g of Cistanche deserticola powder, add 100g of anhydrous ethanol solution thereto, and soak at 90°C for 6h; then increase the pressure to 3MPa, reflux and extract at a temperature of 120°C for 3h; add red Phaffia yeast after cooling to room temperature, and ferment for 10h; heat to boiling again, cool and filter the filtrate to obtain Cistanche deserticola extract; add 55g of Epimedium extract and 35g of Cistanche deserticola extract to the mixed solution A in step S1, stir and mix at a temperature of 100°C and a rate of 600r / min for 50min to obtain a mixed solution B; the red Phaffia yeast is from Nanjing Hegu Life Biotechnology Co., Ltd.

[0026] S3: crush honeysuckle to 200-300 mesh to obtain honeysuckle powder; take 20g honeysuckle powder, 6g cetyl ethylhexanoate, 35g butylene glycol, and 40g pentanediol, and perform pulse treatment at a pulse intensity of 5KV / cm, a pulse width of 12μs, and a pulse number of 60; then perform ultrasonic treatment at a temperature of 50°C and a power of 80W for 60min; then centrifuge and filter, collect the filtrate to obtain the honeysuckle extract; add 50g of clove extract and 45g of honeysuckle extract to the mixed solution in step S2, and stir and mix at a temperature of 60°C and a speed of 800r / min for 3h to obtain the delayed spray.

[0027] Example 3 This embodiment provides a method for preparing a male erection-promoting and delaying spray, comprising the following steps: S1: Crush Cynomorium songaricum to 200-500 mesh to obtain Cynomorium songaricum ultrafine powder; take 15g Cynomorium songaricum ultrafine powder, 70g water, 4g chitosan and 0.35g protease, stir and react at a temperature of 55°C at a rate of 500r / min for 1.5h; then heat to 92°C, keep warm for 16min, and filter through a 0.5-1um filter membrane to obtain Cynomorium songaricum extract; take 55g Zanthoxylum fruit extract, 35g saffron extract, 65g Cynomorium songaricum extract and 35g Cnidium monnieri extract, mix them, stir and mix at a temperature of 65°C at a rate of 800r / min for 50min to obtain mixed solution A; the protease is a neutral protease, 50U / mg, Hunan Yunbang Biotechnology Co., Ltd.

[0028] S2: Crush Cistanche deserticola to 300-500 mesh to obtain Cistanche deserticola powder; take 18g of Cistanche deserticola powder, add 80g of anhydrous ethanol solution thereto, and soak at 85°C for 5.5h; then increase the pressure to 2.5MPa, reflux and extract at a temperature of 110°C for 2h; add red Phaffia yeast after cooling to room temperature, and ferment for 9h; heat to boiling again, cool and filter the filtrate to obtain Cistanche deserticola extract; add 40g of Epimedium extract and 30g of Cistanche deserticola extract to the mixed solution A in step S1, stir and mix at a temperature of 90°C and a speed of 600r / min for 35min to obtain a mixed solution B; the red Phaffia yeast is from Nanjing Hegu Life Biotechnology Co., Ltd.

[0029] S3: crush honeysuckle to 200-300 mesh to obtain honeysuckle powder; take 15g honeysuckle powder, 5g cetyl ethylhexanoate, 30g butylene glycol, and 35g pentanediol, and perform pulse treatment at a pulse intensity of 3KV / cm, a pulse width of 10μs, and a pulse number of 40; then perform ultrasonic treatment at a temperature of 45°C and a power of 65W for 45min; then centrifuge and filter, collect the filtrate to obtain the honeysuckle extract; add 40g of clove extract and 40g of honeysuckle extract to the mixed solution of step S2, and stir and mix at a temperature of 55°C and a speed of 450r / min for 2.5h to obtain the delayed spray.

[0030] Comparative Example 1 The difference between this comparative example and Example 1 is that the Cynomorium songaricum extract in step S1 adopts the product of Snort, and the other steps are the same.

[0031] Comparative Example 2 The difference between this comparative example and Example 1 is that the Cistanche deserticola extract in step S2 adopts the product of Snort, and the other steps are the same.

[0032] Comparative Example 3 The difference between this comparative example and Example 1 is that the honeysuckle extract in step S3 adopts the product of Lanzhou Waters, and the other steps are the same.

[0033] Comparative Example 4 The difference between this comparative example and Example 1 is that no Zanthoxylum bungeanum fruit extract and saffron extract are added in step S1, and the other steps are the same.

[0034] Comparative Example 5 The difference between this comparative example and Example 1 is that no Cistanche extract is added in step S2, and the other steps are the same.

[0035] Comparative Example 6 The difference between this comparative example and Example 1 is that pulse treatment is not used in step S3, and the other steps are the same.

[0036] The Zanthoxylum bungeanum fruit extract, epimedium extract, saffron extract, clove flower extract, and cnidium monnieri extract in the above examples were all purchased from Shaanxi Snort Biotechnology.

[0037] Performance Testing: Randomly select 50 patients with premature ejaculation; spray the spray prepared in the embodiment and the comparative example on the coronal sulcus of the glans penis, respectively, once every 2 days, and the experimental test time is 20 days. Efficacy judgment: Cured: After the penis enters the vagina, the penis erection and sexual intercourse time is at least greater than 30 minutes. Effective: The penis erection and sexual intercourse time is 15-20 minutes. Improved: The penis erection and sexual intercourse time is extended by 5 minutes compared with before treatment. Ineffective: Those who have no progress after treatment are ineffective. Effective rate = (cured + effective + improved) / total number of people.

[0038] Take 5 mL of the spray in the embodiment and the comparative example respectively, and inject them into sterile plates respectively; soak the pre-prepared bacterial slices of Escherichia coli and Staphylococcus aureus in the antibacterial gel for 3 minutes respectively. Transfer the bacterial slices into test tubes respectively, add sterile physiological saline, and shake them thoroughly; after shaking and mixing, take 1.0 ml and apply it to the plate for culture. Count the colonies after they grow, and calculate the antibacterial rate.

[0039] Table 1 Performance test results

[0040] From the above performance test results, it can be seen that the effective rate and antibacterial rate of Examples 1-3 are both above 98%, and the erection delay and antibacterial effects are obvious; in particular, the comprehensive performance of Example 3 is the most outstanding. However, because Comparative Examples 1-6 do not adopt the necessary technical solutions, they are significantly worse than the examples in the corresponding performance tests. The above experimental results further prove the importance of the technical solutions defined in the present invention for its technical effects.

[0041] The above is a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A male erection delay spray, characterized in that: The invention comprises the following components in parts by weight: 40-60 parts of Zanthoxylum bungeanum fruit extract, 35-55 parts of epimedium extract, 25-45 parts of saffron extract, 40-80 parts of Cynomorium songaricum extract, 30-50 parts of clove flower extract, 25-35 parts of Cistanche deserticola extract, 20-40 parts of Cnidium monnieri extract and 25-45 parts of Honeysuckle extract.

2. A male erection delay spray according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 55 parts of Zanthoxylum bungeanum fruit extract, 40 parts of epimedium extract, 35 parts of saffron extract, 65 parts of Cynomorium songaricum extract, 40 parts of clove flower extract, 30 parts of Cistanche deserticola extract, 35 parts of Cnidium monnieri extract and 40 parts of Honeysuckle extract.

3. A method for preparing a male erection-aiding and delayed ejaculation spray, characterized in that: The steps include: S1: Mix 40-60 parts of Zanthoxylum bungeanum fruit extract, 25-45 parts of Crocus sativum extract, 40-80 parts of Cynomorium songaricum extract and 20-40 parts of Cnidium monnieri extract by weight, and stir and mix at a temperature of 50-70° C. for 40-60 minutes; S2: Add 35-55 parts of Epimedium extract and 25-35 parts of Cistanche extract to step S1, and stir and mix at a temperature of 80-100° C. for 30-50 minutes; S3: Add 30-50 parts of clove extract and 25-45 parts of honeysuckle extract to step S2, and stir and mix at a temperature of 40-60° C. for 1-3 hours to obtain the delayed spray.

4. The method for preparing a male erection delay spray according to claim 3, characterized in that: The preparation process of the Cynomorium songaricum extract in step S1 is as follows: ultrafinely crush the Cynomorium songaricum to obtain the Cynomorium songaricum ultrafine powder; take 10-20 parts of the Cynomorium songaricum ultrafine powder, 50-80 parts of water, 3-5 parts of chitosan and 0.2-0.4 parts of protease by weight, and stir the reaction at a temperature of 40-60°C for 1-2h; then heat it to 85-95°C, keep it warm for 10-20min, and then filter it through a 0.5-1um filter membrane to obtain the Cynomorium songaricum extract.

5. The method for preparing a male erection delay spray according to claim 4, characterized in that: The optimized preparation process of Cynomorium songaricum extract is as follows: ultrafinely grind Cynomorium songaricum to 500 mesh to obtain ultrafine Cynomorium songaricum powder; take 15 parts of ultrafine Cynomorium songaricum powder, 70 parts of water, 4 parts of chitosan and 0.35 parts of protease by weight, and stir the reaction at a temperature of 55°C for 1.5 hours; then heat to 92°C, keep warm for 16 minutes, and then filter through a 0.5-1um filter membrane to obtain the Cynomorium songaricum extract.

6. The method for preparing a male erection delay spray according to claim 3, characterized in that: The preparation process of the Cistanche deserticola extract in step S2 is as follows: take 15-25 parts of Cistanche deserticola powder by weight, add 60-100 parts of anhydrous ethanol solution thereto, and soak at 80-90°C for 4-6h; then increase the pressure to 1-3MPa, reflux and extract at a temperature of 105-120°C for 1-3h; add red Phaffia yeast after cooling to room temperature, and ferment for 8-10h; heat to boiling, cool, filter and obtain the filtrate to obtain the Cistanche deserticola extract.

7. The method for preparing a male erection-aiding and delaying spray according to claim 6, characterized in that: The optimized preparation process of the Cistanche deserticola extract is as follows: take 18 parts of 200-300 mesh Cistanche deserticola powder, add 80 parts of anhydrous ethanol solution thereto, and soak at 85°C for 5.5 hours; then increase the pressure to 2.5MPa, reflux and extract at a temperature of 110°C for 2 hours; after cooling to room temperature, add red Phaffia yeast, and ferment for 9 hours; then heat to boiling, cool, filter and obtain the filtrate to obtain the Cistanche deserticola extract.

8. The method for preparing a male erection-aiding and delaying spray according to claim 3, characterized in that: The preparation process of the honeysuckle extract in step S3 is as follows: take 10-20 parts of honeysuckle powder, 3-6 parts of cetyl ethylhexanoate, 25-35 parts of butylene glycol, and 20-40 parts of pentanediol by weight, and perform pulse treatment at a pulse intensity of 1-5KV / cm, a pulse width of 8-12μs, and a pulse number of 30-60; then perform ultrasonic treatment at a temperature of 30-50°C and a power of 50-80W for 30-60min; then centrifuge and filter, and collect the filtrate to obtain the honeysuckle extract.

9. The method for preparing a male erection-aiding and delaying spray according to claim 8, characterized in that: The optimized preparation process of honeysuckle extract is as follows: 15 parts of honeysuckle powder, 5 parts of cetyl ethylhexanoate, 30 parts of butylene glycol, and 35 parts of pentanediol are taken by weight, and pulse treatment is performed at a pulse intensity of 3 KV / cm, a pulse width of 10 μs, and a pulse number of 40; Then, the mixture was ultrasonically treated at a temperature of 45°C and a power of 65W for 45 minutes; then, the mixture was centrifuged and filtered, and the filtrate was collected to obtain the honeysuckle extract.

10. The method for preparing a male erection-aiding and delaying spray according to claim 3, characterized in that: In step S1, the mixture is stirred and mixed at a rate of 800 r / min for 50 min at a temperature of 65°C; in step S2, the mixture is stirred and mixed at a rate of 600 r / min for 35 min at a temperature of 90°C; and in step S3, the mixture is stirred and mixed at a rate of 450 r / min for 2.5 h at a temperature of 55°C to obtain the delayed spray.

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