Device for separating and extracting blood after centrifugal layering

Abstract

The invention relates to the field of medical instruments, in particular to a device for separating and extracting blood after centrifugal layering, which comprises a centrifugal outer cylinder, a separation cylinder and an extraction needle cylinder, the separation cylinder is mounted in the centrifugal outer cylinder in a limited manner, a connector is arranged at the upper part of the separation cylinder, and a piston head is mounted on the outer side of the connector in a sleeving manner; a rubber extension cover is installed on the upper portion of the piston head through an extension film, an extraction needle cylinder is arranged in the separation cylinder, and an extraction nozzle of the extraction needle cylinder is communicated with the top of the separation cylinder. According to the blood supernatant extraction device, when blood supernatant obtained after centrifugation is extracted, a piston rod of an extraction needle cylinder is drawn to extract a supernatant layer, in the extraction process, a push plate arranged on the outer side of a separation cylinder is pushed, so that the push plate drives a connecting support to push a steel bar in a rubber extension cover, and under the limiting effect of a spring, the steel bar in the rubber extension cover is separated from the separation cylinder; the steel bars deform and tilt outwards through the rotating frame, so that the whole rubber extension cover is in a concave shape, clear liquid can be effectively prevented from remaining on the outer side, and the separation and extraction effect is improved.

Description

Technical Field

[0001] The invention relates to the technical field of medical devices, and in particular to a blood centrifugal stratification separation and extraction device. Background Art

[0002] Platelets can promote blood coagulation and wound healing, and also play an important role in tissue regeneration because they produce messenger substances, also known as growth factors. These growth factors absorb stem cells and reserve cells and induce differentiation, thereby forming new tissues through proliferation. Currently, platelet-rich plasma is generally extracted by blood centrifugation.

[0003] In blood extraction, blood is separated into three layers after centrifugation: supernatant (upper layer), platelet-rich plasma layer (middle layer), and red blood cell layer (lower layer). Due to the influence of the internal piston of the existing traditional separation and extraction device, most of the supernatant is above the conical rubber piston, so that part of the supernatant remains around the bottom side of the piston during the extraction process, that is, it is impossible to completely extract it from the bottom center hole of the conical rubber piston, which leads to poor separation and extraction effect. Therefore, there is an urgent need for a blood centrifugal stratification separation and extraction device. Summary of the invention

[0004] The purpose of the present invention is to solve the shortcomings of the prior art and to propose a blood centrifugal stratification separation and extraction device.

[0005] In order to achieve the above object, the present invention adopts the following technical solutions: A blood centrifugal layer separation and extraction device, comprising a centrifugal outer cylinder, a separation cylinder, and an extraction syringe, wherein the separation cylinder is limitedly installed inside the centrifugal outer cylinder, a connector is provided on the upper part of the separation cylinder, a piston head is sleeved and installed on the outer side of the connector, a rubber extension cover is installed on the upper part of the piston head through an extension membrane, and an extraction syringe is provided inside the separation cylinder, and the extraction nozzle of the extraction syringe is connected to the top of the separation cylinder; The inner part of the centrifugal outer cylinder is provided with a rubber extension cover through the limiting position of the separation cylinder, and the rubber extension cover and the inner part of the centrifugal outer cylinder form a centrifugal cavity, the centrifugal cavity is used to extract blood, and an extraction syringe is provided in the middle part of the separation cylinder, and the extraction nozzle of the extraction syringe extends into the inner part of the top of the separation cylinder and is connected with the centrifugal cavity; A push plate is provided on the outer side of the separation cylinder, and a plurality of connecting brackets are installed on the inner wall of the push plate. The connecting bracket extends into the interior of the separation cylinder and is connected to the push rod. One end of the push rod extends into the interior of the connecting head and is connected to a steel bar. One end of the steel bar is connected to a rubber extension cover, and the other end is connected to a rotating frame through a rotating shaft. A spring is provided on one side of the middle part of the steel bar, and the other end of the spring is connected to one side of the connecting head.

[0006] In addition, a preferred structure is that a through hole is opened in the middle of the connector disposed on the upper part of the separation cylinder to extract liquid, and an extraction syringe is installed in the through hole in a limit position.

[0007] In addition, a preferred structure is that a plurality of slots are opened on the outside of the separation cylinder, and a push plate is slidably installed on the outer wall of the separation cylinder, and a plurality of connecting brackets are provided on the inner wall of the push plate. The connecting brackets penetrate into the interior of the separation cylinder and extend into the top connecting head.

[0008] In addition, a preferred structure is that a push rod is installed at one end of the connecting bracket, one end of the push rod is inserted into a limiting groove opened in the middle of the connecting head, and the push rod passes through the piston head sleeved on the connecting head and extends into the cavity between the rubber extension cover and the piston head.

[0009] In addition, a preferred structure is that multiple rotating frames are installed on the outside of the connecting head, and a steel bar is rotatably installed on one end of the rotating frame through a rotating shaft. The upper part of the steel bar is fit-connected to the top inner wall of the rubber extension cover, and the other end of the steel bar is connected to the outer inner wall of the rubber extension cover.

[0010] In addition, a preferred structure is that a spring is connected to one side of the middle portion of the steel bar, and the other end of the spring is mounted on the outer wall of the connecting head.

[0011] In addition, a preferred structure is that a push rod is rotatably mounted on the middle portion of the steel bar via a rotating pin.

[0012] In addition, a preferred structure is that a plurality of limiting convex rings are provided on the outer wall of the connecting head, a piston head is mounted on the upper limit clamping connection of the limiting convex ring, and the piston head is in compression contact with the inner cylinder wall of the centrifugal outer cylinder.

[0013] In addition, a preferred structure is that an extension membrane is provided on the upper outer side of the piston head, and the other end of the extension membrane is connected to the bottom outer side of the rubber extension cover, wherein the outer side of the rubber extension cover is in compression contact with the inner cylinder wall of the centrifugal outer cylinder.

[0014] The beneficial effects of the present invention are: In the present invention, when the upper clear liquid of the blood after centrifugation is extracted, the clear liquid layer is extracted by pulling the piston rod of the extraction syringe, and during the extraction process, the push plate arranged on the outer side of the separation cylinder is pushed, so that the push plate drives the connecting bracket to push the steel bar in the rubber extension cover, and under the limiting action of the spring, the steel bar is deformed and the outer edge is lifted up through the rotating frame, so that the rubber extension cover is concave as a whole, thereby effectively preventing the clear liquid from remaining on the outside, improving the separation and extraction effect, and ensuring the extraction accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a schematic diagram of the internal structure of a blood centrifugal stratification separation and extraction device proposed by the present invention; Figure 2 This is a schematic diagram of the external structure of a blood centrifugal stratification separation and extraction device proposed by the present invention; Figure 3 This is a schematic diagram of the connection structure of the separation cylinder of a device for separating and extracting blood after centrifugal stratification proposed by the present invention; Figure 4 This is a cross-sectional view of the internal structure of a device for separating and extracting blood after centrifugation and stratification proposed by the present invention; Figure 5 This is a schematic diagram of the structure of a connecting bracket of a blood centrifugal stratification separation and extraction device proposed by the present invention; Figure 6 This is a schematic diagram of the connection structure of a rubber extension cover of a blood centrifugal stratification separation and extraction device proposed by the present invention; Figure 7 This is a schematic diagram of the internal structure of a rubber extension cover of a blood centrifugal stratification separation and extraction device proposed by the present invention.

[0016] In the figure: 1. centrifugal outer cylinder; 2. separation cylinder; 21. connecting head; 211. limiting convex ring; 3. extraction syringe; 4. push plate; 41. connecting bracket; 5. sealing cover; 6. piston head; 7. rubber extension cover; 71. extension membrane; 8. push rod; 9. rotating pin; 10. steel bar; 11. rotating frame; 12. rotating shaft; 13. spring; 14. limiting groove. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0018] Reference Figure 1-7 A blood centrifugal layer separation and extraction device, comprising a centrifugal outer cylinder 1, a separation cylinder 2, and an extraction syringe 3, wherein the separation cylinder 2 is installed in a limited position inside the centrifugal outer cylinder 1, a connector 21 is provided on the upper part of the separation cylinder 2, a piston head 6 is sleeved and installed on the outer side of the connector 21, a rubber extension cover 7 is installed on the upper part of the piston head 6 through an extension membrane 71, and an extraction syringe 3 is provided inside the separation cylinder 2, and an extraction nozzle of the extraction syringe 3 is connected to the top of the separation cylinder 2; Furthermore, a rubber extension cover 7 is installed inside the centrifugal outer cylinder 1 through the separation cylinder 2 to limit the position. The rubber extension cover 7 and the inside of the centrifugal outer cylinder 1 form a centrifugal cavity, which is used to extract blood. An extraction syringe 3 is provided in the middle of the separation cylinder 2, and the extraction nozzle of the extraction syringe 3 extends into the top of the separation cylinder 2 and is connected to the centrifugal cavity. Furthermore, a push plate 4 is provided on the outer side of the separation cylinder 2, and a plurality of connecting brackets 41 are installed on the inner wall of the push plate 4. The connecting bracket 41 extends into the interior of the separation cylinder 2 and is connected to the push rod 8. One end of the push rod 8 extends into the interior of the connecting head 21 and is connected to the steel bar 10. One end of the steel bar 10 is connected to the rubber extension cover 7, and the other end is connected to the rotating frame 11 through a rotating shaft 12, wherein a spring 13 is provided on one side of the middle part of the steel bar 10, and the other end of the spring 13 is connected to one side of the connecting head 21.

[0019] Furthermore, a through hole is opened in the middle of the connector 21 disposed on the upper part of the separation cylinder 2 to extract liquid, and an extraction syringe 3 is installed in the through hole in a limit position, and the separated blood in the centrifugal outer cylinder 1 is extracted in layers through the extraction syringe 3.

[0020] Furthermore, a plurality of slots are provided on the outside of the separation cylinder 2, and a push plate 4 is installed on the outer wall of the separation cylinder 2 for limited sliding. A plurality of connecting brackets 41 are provided on the inner wall of the push plate 4. The connecting brackets 41 penetrate into the interior of the separation cylinder 2 and extend into the top connecting head 21, wherein the push plate 4 is limited to slide on the outside of the separation cylinder 2 to ensure the movement stability of the push plate 4.

[0021] Furthermore, a push rod 8 is installed at one end of the connecting bracket 41, one end of the push rod 8 is inserted into the limiting groove 14 opened in the middle of the connecting head 21, and the push rod 8 passes through the piston head 6 sleeved on the connecting head 21 and extends into the cavity between the rubber extension cover 7 and the piston head 6.

[0022] Furthermore, multiple rotating frames 11 are installed on the outside of the connecting head 21, and a steel bar 10 is rotatably installed on one end of the rotating frame 11 through a rotating shaft 12. The upper part of the steel bar 10 is fitted and connected to the top inner wall of the rubber extension cover 7, and the other end of the steel bar 10 is connected to the outer inner wall of the rubber extension cover 7.

[0023] Furthermore, a spring 13 is connected to one side of the middle of the steel bar 10, and the other end of the spring 13 is installed on the outer wall of the connecting head 21. The steel bar 10 is limited by the spring 13. When the steel bar 10 moves, the spring 13 stretches a part of the steel bar 10, thereby causing the steel bar 10 to produce a certain amount of deformation.

[0024] Furthermore, a push rod 8 is rotatably mounted on the middle portion of the steel bar 10 via a rotating pin 9 .

[0025] Furthermore, a plurality of limiting protrusions 211 are provided on the outer wall of the connecting head 21 , and a piston head 6 is mounted on the upper limit clamping of the limiting protrusions 211 , and the piston head 6 is in compression contact with the inner wall of the centrifugal outer cylinder 1 .

[0026] Furthermore, an extension membrane 71 is provided on the outer side of the upper part of the piston head 6 , and the other end of the extension membrane 71 is connected to the outer side of the bottom of the rubber extension cover 7 , wherein the outer side of the rubber extension cover 7 is in compression contact with the inner cylinder wall of the centrifugal outer cylinder 1 .

[0027] In this embodiment, the blood to be tested is extracted through the centrifugal outer cylinder 1, and then the centrifugal outer cylinder 1 is placed in an external centrifuge for centrifugal treatment. Then, during the centrifugal movement, the blood forms multiple layers, namely, supernatant (upper layer), platelet-rich plasma layer (middle layer), and red blood cell layer (lower layer). Then, the supernatant is extracted through the extraction syringe 3. During the extraction process, the supernatant enters the extraction syringe 3, and since the liquid volume inside the centrifugal outer cylinder 1 is reduced, the separation cylinder 2 moves relatively. During the continuous extraction process, the supernatant gradually decreases and the middle layer gradually approaches the extraction nozzle of the extraction syringe 3. At this time, the push plate 4 set on the outside of the separation cylinder 2 is pushed upward, and the push plate 4 drives the connecting bracket 4 1 A pair of push rods 8 are lifted, and the push rods 8 move in the connecting head 21 and lift the steel bar 10 installed in the rubber extension cover 7 under the lifting action. The steel bar 10 is rotated through the rotating frame 11 connected to one side, and drives the outer side of the rubber extension cover 7 to move. During the rotation of the steel bar 10, since the steel bar 10 has certain toughness and resilience, after the steel bar 10 rotates to a certain angle, the spring 13 connected thereto stretches the middle part thereof, and makes the steel bar 10 bend and concave. At this time, the steel bar 10 bends from the upper arc to the lower arc, and drives the rubber extension cover 7 to form a concave shape, thereby guiding the upper clear liquid into the concave cavity. At this time, the clear liquid can be extracted more conveniently to be completely extracted.

[0028] Among them, during actual use, one side of the steel bar 10 is lifted and deformed, and drives the outer side of the rubber extension cover 7 connected to it to be lifted. The height of the outer side of the rubber extension cover 7 is gradually higher than the height of the inner side of the rubber extension cover 7, and under the action of the extension membrane 71, the stability of its connection with the piston head 6 is guaranteed.

[0029] In actual use, when the extraction is completed, by loosening the push plate 4, the steel bar 10 is bent and reset under the contraction of the spring 13, and the rubber extension cover 7 is driven to reset.

[0030] In actual use, a sealing cover 5 is installed at the top of the centrifugal outer cylinder 1 to ensure the airtightness of the internal cavity.

[0031] In the present invention, when extracting the upper clear liquid of the blood after centrifugation, the clear liquid layer is extracted by pulling the piston rod of the extraction syringe 3. During the extraction process, the push plate 4 arranged on the outside of the separation cylinder 2 is pushed, so that the push plate 4 drives the connecting bracket 41 to push the steel bar 10 in the rubber extension cover 7, and under the limiting action of the spring 13, the steel bar is deformed and the outer edge is lifted up through the rotating frame 11, so that the rubber extension cover 7 is concave as a whole, which can effectively prevent the clear liquid from remaining on the outside, improve the separation and extraction effect, and ensure the extraction accuracy.

[0032] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A blood centrifugal layer separation and extraction device, comprising a centrifugal outer cylinder (1), a separation cylinder (2), and an extraction syringe (3), characterized in that: The centrifugal outer cylinder (1) is provided with a separation cylinder (2) at a limited position inside, a connector (21) is provided on the upper part of the separation cylinder (2), a piston head (6) is sleeved and installed on the outer side of the connector (21), a rubber extension cover (7) is installed on the upper part of the piston head (6) through an extension membrane (71), and an extraction syringe (3) is provided inside the separation cylinder (2), and an extraction nozzle of the extraction syringe (3) is connected to the top of the separation cylinder (2); A rubber extension cover (7) is installed inside the centrifugal outer cylinder (1) through the separation cylinder (2) to limit the position of the rubber extension cover (7) and the inside of the centrifugal outer cylinder (1) to form a centrifugal cavity for extracting blood. An extraction syringe (3) is provided in the middle of the separation cylinder (2) and is connected to the separation cylinder (2). The extraction nozzle of the extraction syringe (3) extends into the top of the separation cylinder (2) and is connected to the centrifugal cavity. A push plate (4) is provided on the outer side of the separation cylinder (2), and a plurality of connecting brackets (41) are installed on the inner wall of the push plate (4). The connecting brackets (41) extend into the interior of the separation cylinder (2) and are connected to the push rod (8). One end of the push rod (8) extends into the interior of the connecting head (21) and is connected to the steel bar (10). One end of the steel bar (10) is connected to the rubber extension cover (7), and the other end is connected to the rotating frame (11) via a rotating shaft (12). A spring (13) is provided on one side of the middle of the steel bar (10), and the other end of the spring (13) is connected to one side of the connecting head (21).

2. The blood centrifugal separation and extraction device according to claim 1, characterized in that: A through hole is provided in the middle of the connector (21) disposed on the upper part of the separation cylinder (2) for extracting liquid, and an extraction syringe (3) is positioned and clamped in the through hole.

3. The blood centrifugal separation and extraction device according to claim 1, characterized in that: The exterior of the separation cylinder (2) is provided with a plurality of notches, and a push plate (4) is slidably mounted on the outer wall of the separation cylinder (2), and the inner wall of the push plate (4) is provided with a plurality of connecting brackets (41), which penetrate into the interior of the separation cylinder (2) and extend into the top connecting head (21).

4. The blood centrifugal stratification separation and extraction device according to claim 3, characterized in that: A push rod (8) is mounted on one end of the connecting bracket (41), one end of the push rod (8) is inserted into a limiting groove (14) provided in the middle of the connecting head (21), and the push rod (8) passes through a piston head (6) sleeved on the connecting head (21) and extends into a cavity between the rubber extension cover (7) and the piston head (6).

5. The blood centrifugal separation and extraction device according to claim 4, characterized in that: A plurality of rotating frames (11) are mounted on the outside of the connecting head (21), and a steel bar (10) is rotatably mounted on one end of the rotating frame (11) via a rotating shaft (12). The upper portion of the steel bar (10) is fitted and connected to the top inner wall of the rubber extension cover (7), and the other end of the steel bar (10) is connected to the outer inner wall of the rubber extension cover (7).

6. The blood centrifugal separation and extraction device according to claim 5, characterized in that: A spring (13) is connected to one side of the middle portion of the steel bar (10), and the other end of the spring (13) is mounted on the outer wall of the connecting head (21).

7. The blood centrifugal stratification separation and extraction device according to claim 5, characterized in that: A push rod (8) is rotatably mounted on the middle portion of the steel bar (10) via a rotating pin (9).

8. The blood centrifugal separation and extraction device according to claim 1, characterized in that: The outer wall of the connecting head (21) is provided with a plurality of limiting convex rings (211), and the upper limit clamping of the limiting convex rings (211) is mounted with a piston head (6), and the piston head (6) is in compression contact with the inner cylinder wall of the centrifugal outer cylinder (1).

9. The blood centrifugal separation and extraction device according to claim 8, characterized in that: An extension membrane (71) is provided on the outer side of the upper part of the piston head (6), and the other end of the extension membrane (71) is connected to the outer side of the bottom of the rubber extension cover (7), wherein the outer side of the rubber extension cover (7) is in compression contact with the inner cylinder wall of the centrifugal outer cylinder (1).

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