A PUR hot melt adhesive with good biocompatibility and a preparation method thereof

Abstract

The application relates to the technical field of hot melt adhesives, and particularly discloses a PUR hot melt adhesive with good biocompatibility and a preparation method thereof. The raw material of the PUR hot melt adhesive with good biocompatibility comprises the following components in parts by weight: 80-90 parts of polyester type polyurethane, 5-15 parts of tackifier, 1-5 parts of softening agent, 1-5 parts of biocompatibility auxiliary agent, 5-10 parts of slip agent and 5-10 parts of silane modified talc powder. The silane modified talc powder has good dispersing performance; the talc powder in the silane modified talc powder can not only improve the viscosity of the PUR hot melt adhesive, but also has certain lubricating effect; and the softening agent, the biocompatibility auxiliary agent and the slip agent are combined, so that the skin-friendly performance of the prepared PUR hot melt adhesive is improved.

Description

Technical Field

[0001] This application relates to the technical field of hot melt adhesives, and in particular to a biocompatible PUR hot melt adhesive and its preparation method. Background Technology

[0002] PUR is a moisture-curing reactive polyurethane hot melt adhesive. Its main component is isocyanate-terminated polyurethane prepolymer. PUR offers adjustable adhesion and toughness, and boasts excellent bond strength, temperature resistance, chemical resistance, and aging resistance. In recent years, it has become one of the most important adhesive products in the industry. It is widely used in packaging, wood processing, automotive, textile, electromechanical, and aerospace sectors of the national economy. However, commonly used PUR hot melt adhesives have a poor skin-friendly feel after curing, thus limiting their application range. Summary of the Invention

[0003] To improve the skin-friendly properties of PUR hot melt adhesives, this application provides a biocompatible PUR hot melt adhesive and its preparation method.

[0004] In a first aspect, this application provides a biocompatible PUR hot melt adhesive, which adopts the following technical solution: a biocompatible PUR hot melt adhesive, wherein the raw materials of the PUR hot melt adhesive include the following components in parts by weight: 80-90 parts of polyester polyurethane, 5-15 parts of tackifier, 1-5 parts of softener, 1-5 parts of biocompatible additive, 5-10 parts of slip agent, and 5-10 parts of silane-modified talc.

[0005] By adopting the above technical solution, silane-modified talc powder has good dispersibility. The talc powder in silane-modified talc powder can not only increase the viscosity of PUR hot melt adhesive, but also has a certain lubricating effect. With the combination of softener, biocompatible additives and slip agents, the skin-friendly properties of the prepared PUR hot melt adhesive are improved.

[0006] In one specific implementation, the method for preparing the silane-modified talc powder includes the following steps:

[0007] γ-aminopropyltriethoxysilane, ethanol, and water were stirred and mixed evenly to obtain the modified solution;

[0008] Talc powder is stirred, and during the stirring process, a modifying liquid is sprayed into the talc powder. After the spraying is completed, stirring is continued, and finally the powder is dried to obtain silane-modified talc powder.

[0009] By adopting the above technical solution, γ-aminopropyltriethoxysilane is first dissolved in ethanol to obtain a modified liquid. Then, while stirring the talc powder, the modified liquid is sprayed. After the spraying is completed, stirring is continued, and finally, the powder is dried to obtain silane-modified talc powder.

[0010] In one specific implementation, the weight ratio of the modified liquid to the talc is 1:(13-14).

[0011] By adopting the above technical solution, the ratio of modified liquid to talc powder is further limited, thereby improving the modification effect of talc powder.

[0012] In one specific implementation, the tackifier comprises one or a mixture of two of rosin resin and terpene resin.

[0013] By adopting the above technical solution, the addition of rosin resin and terpene resin can improve the adhesion performance of the prepared PUR hot melt adhesive.

[0014] In one specific implementation, the softener includes one of silicone oil, vegetable oil, and mineral oil.

[0015] By adopting the above technical solution, the addition of silicone oil, vegetable oil, and mineral oil can give the cured PUR hot melt adhesive a better feel, thus improving the skin-friendly properties of the PUR hot melt adhesive.

[0016] In one specific implementation, the biocompatible adjuvant comprises a mixture of polydimethylsiloxane and glycerol fatty acid esters.

[0017] In one specific embodiment, the slip agent comprises a mixture of ethylene dioleamide and vinyl bis-stearamide.

[0018] By adopting the above technical solution, using a composite biocompatible additive composed of polydimethylsiloxane and glycerol fatty acid esters, and a composite slip agent composed of ethylene dioleamide and vinyl bis-stearamide, the affinity between PUR hot melt adhesive and skin can be improved, thus enhancing the skin-friendly properties of PUR hot melt adhesive.

[0019] In one specific implementation, the raw materials of the PUR hot melt adhesive further include 1 to 3 parts by weight of lignite wax.

[0020] By adopting the above technical solution, the addition of lignite wax can reduce the adhesion and aggregation between raw materials, making the components in PUR hot melt adhesive evenly dispersed, thus further improving the skin-friendly properties of PUR hot melt adhesive.

[0021] Secondly, this application provides a method for preparing a biocompatible PUR hot melt adhesive, which employs the following technical solution:

[0022] A method for preparing a biocompatible PUR hot melt adhesive includes the following steps:

[0023] Polyester-type polyurethane, tackifier, softener, biocompatible additive, slip agent, silane-modified talc, and lignite wax are stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility.

[0024] By adopting the above technical solution, polyester polyurethane, tackifier, softener, biocompatible additive, slip agent, silane-modified talc powder, and lignite wax are first stirred and mixed evenly, and then heated and melted to obtain PUR hot melt adhesive with good biocompatibility.

[0025] In summary, this application includes at least one of the following beneficial technical effects:

[0026] 1. The silane-modified talc in this application has good dispersibility. The talc in the silane-modified talc can not only increase the viscosity of PUR hot melt adhesive, but also has a certain lubricating effect. With the combination of softener, biocompatible additive and slip agent, the skin-friendly properties of the obtained PUR hot melt adhesive are improved.

[0027] 2. The composite biocompatibility additive composed of polydimethylsiloxane and glycerol fatty acid ester, and the composite slip agent composed of ethylene dioleamide and vinyl bis-stearamide used in this application can improve the affinity between PUR hot melt adhesive and skin, thus improving the skin-friendly properties of PUR hot melt adhesive.

[0028] 3. The method in this application involves first stirring and mixing polyester polyurethane, tackifier, softener, biocompatible additive, slip agent, silane-modified talc, and lignite wax evenly, and then heating and melting them to obtain a PUR hot melt adhesive with good biocompatibility. Detailed Implementation

[0029] The present application will be further described in detail below with reference to the embodiments.

[0030] All raw materials used in the embodiments are commercially available. The tackifier includes, but is not limited to, one or a mixture of two of rosin resin and terpene resin, with rosin resin being preferred in this application; the softener includes, but is not limited to, one or a mixture of one or more of silicone oil, vegetable oil, and mineral oil, with silicone oil being preferred in this application.

[0031] Preparation Example

[0032] Preparation Example 1

[0033] Preparation Example 1 provides a method for preparing silane-modified talc powder, comprising the following steps:

[0034] γ-aminopropyltriethoxysilane, ethanol, and water were stirred and mixed evenly to obtain a modified solution; wherein the weight ratio of γ-aminopropyltriethoxysilane, ethanol, and water was 5:18:2.

[0035] Talc powder was added to a high-speed mixer. During the mixing process, a modifying liquid was sprayed onto the talc powder. After spraying, the mixture was stirred for 0.5 hours. Finally, it was dried at 115°C for 2 hours to obtain silane-modified talc powder. The weight ratio of the modifying liquid to the talc powder was 1:12.5.

[0036] Preparation Example 2

[0037] Preparation Example 2 provides a method for preparing silane-modified talc powder, comprising the following steps:

[0038] γ-aminopropyltriethoxysilane, ethanol, and water were stirred and mixed evenly to obtain a modified solution; wherein the weight ratio of γ-aminopropyltriethoxysilane, ethanol, and water was 5:18:2.

[0039] Talc powder was added to a high-speed mixer. During the mixing process, a modifying liquid was sprayed onto the talc powder. After spraying, the mixture was stirred for 0.5 hours. Finally, it was dried at 115°C for 2 hours to obtain silane-modified talc powder. The weight ratio of the modifying liquid to the talc powder was 1:13.

[0040] Preparation Example 3

[0041] Preparation Example 3 provides a method for preparing silane-modified talc powder, comprising the following steps:

[0042] γ-aminopropyltriethoxysilane, ethanol, and water were stirred and mixed evenly to obtain a modified solution; wherein the weight ratio of γ-aminopropyltriethoxysilane, ethanol, and water was 5:18:2.

[0043] Talc powder was added to a high-speed mixer. During the mixing process, a modifying liquid was sprayed onto the talc powder. After spraying, the mixture was stirred for 0.5 hours. Finally, it was dried at 115°C for 2 hours to obtain silane-modified talc powder. The weight ratio of the modifying liquid to the talc powder was 1:13.5.

[0044] Preparation Example 4

[0045] Preparation Example 4 provides a method for preparing silane-modified talc powder, comprising the following steps:

[0046] γ-aminopropyltriethoxysilane, ethanol, and water were stirred and mixed evenly to obtain a modified solution; wherein the weight ratio of γ-aminopropyltriethoxysilane, ethanol, and water was 5:18:2.

[0047] Talc powder was added to a high-speed mixer. During the mixing process, a modifying liquid was sprayed onto the talc powder. After spraying, the mixture was stirred for 0.5 hours. Finally, it was dried at 115°C for 2 hours to obtain silane-modified talc powder. The weight ratio of the modifying liquid to the talc powder was 1:14.

[0048] Preparation Example 5

[0049] Preparation Example 5 provides a method for preparing silane-modified talc powder, comprising the following steps:

[0050] γ-aminopropyltriethoxysilane, ethanol, and water were stirred and mixed evenly to obtain a modified solution; wherein the weight ratio of γ-aminopropyltriethoxysilane, ethanol, and water was 5:18:2.

[0051] Talc powder was added to a high-speed mixer. During the mixing process, a modifying liquid was sprayed onto the talc powder. After spraying, the mixture was stirred for 0.5 hours. Finally, it was dried at 115°C for 2 hours to obtain silane-modified talc powder. The weight ratio of the modifying liquid to the talc powder was 1:14.5.

[0052] Example

[0053] Example 1

[0054] Example 1 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0055] 80 kg of polyester-type polyurethane, 5 kg of tackifier, 1 kg of softener, 1 kg of biocompatible additive, 5 kg of slip agent, and 5 kg of silane-modified talc powder from Preparation Example 1 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is a mixture of polydimethylsiloxane and glycerol fatty acid ester, and the weight ratio of polydimethylsiloxane to glycerol fatty acid ester is 1:1; the slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, and the weight ratio of ethylene dioleamide to vinyl bis-stearamide is 1:1.

[0056] Example 2

[0057] The difference between Example 2 and Example 1 is that the silane-modified talc powder used in Example 2 is selected, while the remaining steps are the same as in Example 1.

[0058] Example 3

[0059] The difference between Example 3 and Example 1 is that the silane-modified talc powder used in Example 3 is selected, while the remaining steps are the same as in Example 1.

[0060] Example 4

[0061] The difference between Example 4 and Example 1 is that the silane-modified talc powder used in Example 4 is selected, while the remaining steps are the same as in Example 1.

[0062] Example 5

[0063] The difference between Example 5 and Example 1 is that the silane-modified talc powder used in Example 5 is selected, while the remaining steps are the same as in Example 1.

[0064] Example 6

[0065] Example 6 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0066] 85 kg of polyester-type polyurethane, 10 kg of tackifier, 3 kg of softener, 3 kg of biocompatible additive, 7.5 kg of slip agent, and 7.5 kg of silane-modified talc powder from Preparation Example 3 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is a mixture of polydimethylsiloxane and glycerol fatty acid ester, and the weight ratio of polydimethylsiloxane to glycerol fatty acid ester is 1:1; the slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, and the weight ratio of ethylene dioleamide to vinyl bis-stearamide is 1:1.

[0067] Example 7

[0068] Example 7 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0069] 90 kg of polyester-type polyurethane, 15 kg of tackifier, 5 kg of softener, 5 kg of biocompatible additive, 10 kg of slip agent, and 10 kg of silane-modified talc powder from Preparation Example 3 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is a mixture of polydimethylsiloxane and glycerol fatty acid ester, and the weight ratio of polydimethylsiloxane to glycerol fatty acid ester is 1:1; the slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, and the weight ratio of ethylene dioleamide to vinyl bis-stearamide is 1:1.

[0070] Example 8

[0071] Example 8 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0072] 85 kg of polyester-type polyurethane, 10 kg of tackifier, 3 kg of softener, 3 kg of biocompatible additive, 7.5 kg of slip agent, and 7.5 kg of silane-modified talc powder from Preparation Example 3 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is polydimethylsiloxane; and the slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, with a weight ratio of ethylene dioleamide to vinyl bis-stearamide of 1:1.

[0073] Example 9

[0074] Example 9 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0075] 85 kg of polyester-type polyurethane, 10 kg of tackifier, 3 kg of softener, 3 kg of biocompatible additive, 7.5 kg of slip agent, and 7.5 kg of silane-modified talc powder from Preparation Example 3 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is glycerol fatty acid ester; and the slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, with a weight ratio of ethylene dioleamide to vinyl bis-stearamide of 1:1.

[0076] Example 10

[0077] Example 10 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0078] 85 kg of polyester-type polyurethane, 10 kg of tackifier, 3 kg of softener, 3 kg of biocompatible additive, 7.5 kg of slip agent, and 7.5 kg of silane-modified talc powder from Preparation Example 3 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is a mixture of polydimethylsiloxane and glycerol fatty acid ester, and the weight ratio of polydimethylsiloxane to glycerol fatty acid ester is 1:1; and the slip agent is ethylene dioleamide.

[0079] Example 11

[0080] Example 11 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0081] 85 kg of polyester-type polyurethane, 10 kg of tackifier, 3 kg of softener, 3 kg of biocompatible additive, 7.5 kg of slip agent, and 7.5 kg of silane-modified talc powder from Preparation Example 3 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is a mixture of polydimethylsiloxane and glycerol fatty acid ester, and the weight ratio of polydimethylsiloxane to glycerol fatty acid ester is 1:1; and the slip agent is vinyl bis-stearamide.

[0082] Example 12

[0083] Example 12 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0084] 85 kg of polyester-type polyurethane, 10 kg of tackifier, 3 kg of softener, 3 kg of biocompatible additive, 7.5 kg of slip agent, 7.5 kg of silane-modified talc powder from Preparation Example 3, and 2 kg of lignite wax were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is a mixture of polydimethylsiloxane and glycerol fatty acid ester, and the weight ratio of polydimethylsiloxane to glycerol fatty acid ester is 1:1; the slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, and the weight ratio of ethylene dioleamide to vinyl bis-stearamide is 1:1.

[0085] Comparative Example

[0086] Comparative Example 1

[0087] Comparative Example 1 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0088] 80 kg of polyester-type polyurethane, 5 kg of tackifier, 1 kg of softener, 1 kg of biocompatible additive, 5 kg of slip agent, and 5 kg of talc powder were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the softener is silicone oil; the biocompatible additive is a mixture of polydimethylsiloxane and glycerol fatty acid ester, and the weight ratio of polydimethylsiloxane to glycerol fatty acid ester is 1:1; the slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, and the weight ratio of ethylene dioleamide to vinyl bis-stearamide is 1:1.

[0089] Comparative Example 2

[0090] Comparative Example 2 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0091] 80 kg of polyester-type polyurethane, 5 kg of tackifier, 1 kg of biocompatible additive, 5 kg of slip agent, and 5 kg of silane-modified talc powder from Preparation Example 1 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier is rosin resin; the biocompatible additive is a mixture of polydimethylsiloxane and glycerol fatty acid ester, and the weight ratio of polydimethylsiloxane to glycerol fatty acid ester is 1:1; the slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, and the weight ratio of ethylene dioleamide to vinyl bis-stearamide is 1:1.

[0092] Comparative Example 3

[0093] Comparative Example 3 provides a method for preparing a biocompatible PUR hot melt adhesive, comprising the following steps:

[0094] 80 kg of polyester-type polyurethane, 5 kg of tackifier, 1 kg of softener, 1 kg of biocompatible additive, and 5 kg of silane-modified talc powder from Preparation Example 1 were stirred and mixed evenly, and then heated to melt, to obtain a PUR hot melt adhesive with good biocompatibility; wherein the tackifier was rosin resin; the softener was silicone oil; and the biocompatible additive was a mixture of polydimethylsiloxane and glycerol fatty acid ester, with a weight ratio of polydimethylsiloxane to glycerol fatty acid ester of 1:1.

[0095] Performance testing of skin-friendliness: The PUR hot melt adhesive was heated at 120℃ and then coated onto the fabric using a 0.4μm pore size rotary screen. After curing, it was placed in a constant temperature and humidity environment of 18℃ and 80% for 48 hours. Ten testers were selected to conduct a hand feel test on the cured PUR hot melt adhesive and then scored it. The average score was taken. The scoring standard was 1-10, with the higher the score, the better the skin-friendliness.

[0096] Table 1 Performance test results of PUR hot melt adhesive

[0097]

[0098]

[0099] Combining Example 1 and Comparative Examples 1-3, the PUR hot melt adhesive in Example 1 exhibits the best skin-friendly properties. This demonstrates that when preparing PUR hot melt adhesive, the addition of silane-modified talc, softener, biocompatible additives, and slip agent, through their combined action, can improve the skin-friendly properties of the prepared PUR hot melt adhesive.

[0100] Based on Examples 1-5, the PUR hot melt adhesive in Examples 2-4 has better skin-friendly properties. It can be seen that when preparing silane-modified talc, the preferred ratio of the modifying liquid to talc is 1:(13-14), which yields better results in preparing silane-modified talc.

[0101] Combining Examples 3, 6, and 7, the PUR hot melt adhesive in Example 6 exhibits the best skin-friendly properties. This suggests that increasing the amount of raw materials used in the preparation of PUR hot melt adhesive initially leads to an increase in the performance of the adhesive, followed by a decrease.

[0102] Combining Examples 6, 8, and 9, the PUR hot melt adhesive in Example 6 exhibits the best skin-friendly properties. This indicates that when preparing PUR hot melt adhesive, the preferred biocompatibility additive is a mixture of polydimethylsiloxane and glycerol fatty acid esters, which results in a PUR hot melt adhesive with good skin-friendly properties.

[0103] Combining Examples 6, 10, and 11, the PUR hot melt adhesive in Example 6 exhibits the best skin-friendly properties. This indicates that when preparing the PUR hot melt adhesive, the preferred slip agent is a mixture of ethylene dioleamide and vinyl bis-stearamide, which results in a PUR hot melt adhesive with good skin-friendly properties.

[0104] Combining Examples 6 and 12, the PUR hot melt adhesive in Example 12 exhibits the best skin-friendly properties. This demonstrates that adding lignite wax to the raw materials during the preparation of PUR hot melt adhesive can ensure the full dispersion of the various components in the PUR hot melt adhesive, thereby further improving its skin-friendly properties.

[0105] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.

Claims

1. A PUR hotmelt glue with good biocompatibility, characterized in that: The raw materials of the PUR hot melt adhesive include the following components in parts by weight: polyester polyurethane 80-90, tackifier 5-15, softening agent 1-5, biocompatible auxiliary agent 1-5, slip agent 5-10, silane modified talc powder 5-10; the preparation method of the silane modified talc powder includes the following steps: uniformly stirring γ-aminopropyl triethoxysilane, ethanol and water to obtain a modified liquid; stirring talc powder, spraying the modified liquid into the talc powder during the stirring, continuing to stir after the spraying is completed, and finally drying to obtain the silane modified talc powder; the softening agent includes silicone oil; the slip agent includes a mixture of ethylene bisoleamide and vinyl bis stearamide.

2. The PUR hot melt adhesive according to claim 1, characterized in that: The weight ratio of the modified liquid to the talc powder is 1: (13-14).

3. The PUR hot melt adhesive according to claim 1, characterized in that: The tackifier includes a mixture of one or both of rosin resin and terpene resin.

4. The PUR hot melt adhesive according to claim 1, characterized in that: The biocompatible auxiliary agent includes a mixture of polydimethylsiloxane and glycerol fatty acid ester.

5. The PUR hot melt adhesive according to claim 1, characterized in that: The raw materials of the PUR hot melt adhesive further include 1-3 parts by weight of lignite wax.

6. A process for the preparation of a biocompatible PUR hotmelt glue according to any one of claims 1 to 5, characterized in that: The method includes the following steps: Uniformly stirring polyester polyurethane, tackifier, softening agent, biocompatible auxiliary agent, slip agent, silane modified talc powder and lignite wax, and then heating and melting to obtain the PUR hot melt adhesive with good biocompatibility. The raw materials of the PUR hot melt adhesive include the following components in parts by weight: polyester polyurethane 80-90, tackifier 5-15, softening agent 1-5, biocompatible auxiliary agent 1-5, slip agent 5-10, silane modified talc powder 5-10; the preparation method of the silane modified talc powder includes the following steps: uniformly stirring γ-aminopropyl triethoxysilane, ethanol and water to obtain a modified liquid; stirring talc powder, spraying the modified liquid into the talc powder during the stirring, continuing to stir after the spraying is completed, and finally drying to obtain the silane modified talc powder; the softening agent includes silicone oil; the slip agent includes a mixture of ethylene bisoleamide and vinyl bis stearamide. The weight ratio of the modified liquid to the talc powder is 1: (13-14). The tackifier includes a mixture of one or both of rosin resin and terpene resin. The biocompatible auxiliary agent includes a mixture of polydimethylsiloxane and glycerol fatty acid ester. The raw materials of the PUR hot melt adhesive further include 1-3 parts by weight of lignite wax. The method includes the following steps: Uniformly stirring polyester polyurethane, tackifier, softening agent, biocompatible auxiliary agent, slip agent, silane modified talc powder and lignite wax, and then heating and melting to obtain the PUR hot melt adhesive with good biocompatibility.

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