A tissue grinding instrument for laboratory samples
By designing a laboratory sample tissue grinder with a locking mechanism, the problem of failure of connective tissue and adipose tissue in the sample was solved, and the uniform grinding of the sample and the accuracy of experimental results was achieved.
Patent Information
- Application Number
- CN202411865549.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-18
- Publication Date
- 2025-05-06
- Estimated Expiration
- 2044-12-18
AI Technical Summary
When processing samples containing connective tissue and adipose tissue, the prior art is difficult to ensure uniform grinding of the samples, resulting in the failure of the connective tissue to completely break down and affecting the accuracy of the experiment, or excessive breakdown of the adipose tissue to release a large number of fat droplets, affecting the experimental results.
A laboratory sample tissue grinder was designed, using a placing plate and locking mechanism. By detecting the height of the test tube, the unit time duration of the locking mechanism is adjusted to ensure that the grinding beads are fully locked in the test tube and avoid excessive tissue being ground.
The uniform grinding of tissues in test tubes at different heights is achieved, avoiding the problems of unbreakable connective tissue and excessive breaking of adipose tissue, and improving the accuracy and efficiency of the experiment.
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Figure CN119319019B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of tissue grinders, in particular to a sample tissue grinder for a laboratory. Background Art
[0002] As a department in a hospital responsible for testing and analyzing various biological samples, the laboratory department often needs to deal with various types of biological tissue samples. These samples may come from patients, experimental animals or other organisms for diagnosing diseases, studying biological processes or developing drugs.
[0003] The sample tissue grinder is one of the commonly used equipment in the laboratory. It can quickly and evenly grind biological tissue samples into tiny particles or homogenates, which is convenient for subsequent extraction, separation and analysis. By using the tissue grinder, the laboratory can more effectively extract the required biological molecules (such as DNA, RNA, protein, etc.) from the samples, thereby improving the accuracy and efficiency of the test.
[0004] Among them, the high-throughput tissue grinder is one of the commonly used sample tissue grinders. When the inspectors operate the high-throughput tissue grinder to grind the sample tissue to be processed, first, put an appropriate amount of sample and grinding balls into a ball mill or centrifuge tube. In biological and medical research, stainless steel grinding beads are usually used to grind animal tissues such as the brain, lungs, liver, kidneys, and gonads. These tissues are usually soft or have a certain toughness, and need to rely on the impact and friction of the grinding beads to break and mix; then, put the ball mill or centrifuge tube containing the sample into the fixture of the high-throughput tissue grinder to ensure that the ball mill or centrifuge tube is symmetrically distributed in the fixture; then, set the appropriate vibration frequency and the running time of the grinder (i.e., vibration time) on the control display. The range of vibration frequency is usually determined according to the sample type, and the vibration time is determined according to the hardness of the sample and the grinding requirements. The appropriate time; finally, cover the safety door of the machine, start the instrument, and start grinding.
[0005] However, when dealing with a large number of samples, doctors usually adopt the method of batch loading. Since the loading of samples is a manual operation, it is difficult to ensure that the loading amount of each test tube is exactly the same, and the proportion and distribution of the components such as fat and connective tissue in the sample tissue are also uneven. Adipose tissue is mainly composed of fat cells, which contain a large number of fat droplets, making the adipose tissue relatively soft and fragile, but connective tissue is a tough tissue type, mainly composed of fibers, cells and matrix. It has strong elasticity and toughness, making it difficult to break during the grinding process. As a result, after setting a fixed vibration time, the doctor's set time is not enough to completely grind the tissue sample with a high connective tissue content, and the connective tissue is not completely broken, affecting the accuracy of subsequent experiments; and for the part with a higher fat content, the set time has already led to over-grinding, excessive crushing of the adipose tissue, and the release of a large number of fat droplets, which also affects the experimental results. It requires high experience for doctors to load sample tissues. For this reason, we propose a sample tissue grinder for the laboratory. Summary of the invention
[0006] The purpose of the present invention is to provide a sample tissue grinder for laboratory departments to solve the problem raised in the above-mentioned background technology that for tissue samples with high connective tissue content, the set time is not enough to completely grind them, and the connective tissue cannot be completely broken, affecting the accuracy of subsequent experiments; and for the parts with high fat content, the set time has caused excessive grinding, excessive breaking of fat tissue, and release of a large number of fat droplets, which also affects the experimental results and requires high experience for doctors to load sample tissues.
[0007] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a laboratory sample tissue grinder, comprising a grinder chassis and a transmission shaft; further comprising a placement plate, the placement plate is fixed to the outside of the transmission shaft, a plurality of placement grooves are provided on the surface of the placement plate, the placement grooves are used to place test tubes, a threaded rod is fixedly connected to one end of the transmission shaft near the placement plate; an upper cover plate, the upper cover plate is slidably connected to the threaded rod, and a limit cover, the limit cover is threadedly connected to the threaded rod;
[0008] A locking mechanism, which is located outside the plurality of placement slots. Each time the placement plate moves downward in the vertical direction, the locking mechanism locks the grinding beads that fall to the bottom of the test tube within a unit time.
[0009] The regulating mechanism is connected with the limit cover, and the regulating mechanism adjusts the unit time duration of the locking mechanism during the working process according to the height of the test tube placed in the placing plate.
[0010] Among them, the locking mechanism includes multiple strong magnetic blocks, the number of strong magnetic blocks is the same as the number of placement slots, each strong magnetic block is located below the corresponding placement slot, the inner wall of the placement disk is provided with a sliding groove that is slidably connected to the strong magnetic block, a moving rod is fixedly connected to the bottom of the strong magnetic block, the moving rod is slidably connected to the inner wall of the placement disk, an electromagnet is provided below the placement disk, the electromagnet is fixedly connected to the inner wall of the grinder chassis, a moving part is provided on the inner wall of the placement disk for pushing the moving rod to move when the electromagnet is energized, a blocking part is provided on the inner wall of the sliding groove for blocking the magnetic field, and the blocking part releases the blocking of the magnetic field when the strong magnetic block moves upward.
[0011] Among them, the moving part includes an iron block slidably connected to the inner wall of the placing plate, the inner wall of the placing plate is provided with a transmission groove slidably connected to the iron block, the upper end of the iron block is fixedly connected with an elastic rope, the elastic rope is fixed to the inner wall of the transmission groove, the lower end of the iron block is fixedly connected with a push rod, a transmission pipe is connected between the transmission groove and the sliding groove, the push rod and the moving rod are respectively slidably connected to the inner wall of the transmission pipe, the inner wall of the transmission pipe is provided with a bead chain, and the two ends of the bead chain are respectively fixed to the moving rod and the push rod.
[0012] Among them, the barrier includes a magnetic field shielding plate located on the inner wall of the sliding groove, a moving groove slidably connected to the magnetic field shielding plate is opened on the inner wall of the placement plate, a return spring is fixedly connected to the side of the magnetic field shielding plate, the return spring is slidably connected to the inner wall of the moving groove, and a transmission part is provided between the magnetic field shielding plate and the strong magnetic block.
[0013] The magnetic field shielding plate is made of high magnetic permeability materials, such as iron, nickel, cobalt and alloys thereof.
[0014] The thickness of the magnetic field shielding plate is smaller than the thickness of the strong magnetic block.
[0015] Among them, the transmission part includes a transmission rope fixedly connected to the magnetic field shielding plate, the transmission rope is slidably connected to the inner wall of the placement disk, the end of the transmission rope away from the magnetic field shielding plate is fixedly connected to a winding disk one, the winding disk one is rotatably connected to the inner wall of the placement disk, the inner wall of the placement disk is rotatably connected to a winding disk two, the winding disk two is coaxial with the winding disk, a connecting rope is wound on the outer side of the winding disk two, and the end of the connecting rope away from the winding disk two is fixed to the bottom of the strong magnetic block.
[0016] Among them, the diameter of the winding reel 1 is larger than the diameter of the winding reel 2.
[0017] Among them, the regulating mechanism includes a trigger rod slidably connected to the inner wall of the limit cover, and one end of the trigger rod connected to the outside is fixedly connected to a baffle. The grinder chassis includes a box body and a box cover. The box cover is hinged to the box body. An infrared distance sensor for detecting the movement of the baffle is installed on the inner wall of the box cover, and the infrared distance sensor is connected to the electromagnet.
[0018] The baffle is in an inverted concave shape, and is slidably connected to the inner wall of the limiting cover.
[0019] The present invention has at least the following beneficial effects:
[0020] When the present application is in use, the height of the test tube placed in the placement tray is detected by the provided regulating mechanism, and the unit time duration of the locking mechanism during the working process is adjusted according to the height of the test tube, so as to cooperate with the grinding of tissues in test tubes of different heights. The locking mechanism locks the grinding beads in the test tube that have been ground sufficiently, thereby preventing the tissues in the test tube from being over-grinded and affecting the experimental results.
[0021] Each time the placement plate moves downward in the vertical direction, the grinding beads in the test tube will move relative to the test tube due to inertia, causing the grinding beads to be located at the top of the test tube. When the grinding beads are located at the top of the test tube, although the transmission shaft drives the placement plate to rotate, the grinding beads will slide downward in the test tube under the action of their own gravity. The tissue samples in the test tube are ground to different degrees. The tissue samples that are not fully ground remain in large blocks or clumps, and the fibrous network formed by the connective tissue will hinder the falling of the grinding beads, while the tissue samples that are fully ground have been ground into smaller particles or powders. These particles or powders have less hindering effect on the falling of the grinding beads, resulting in different falling times of the grinding beads in the fully ground and inadequately ground test tubes. Based on the falling time period of the grinding beads in the fully ground sample tissue test tube as the unit time, the time for the grinding beads to fall at the top of the test tubes at different heights is also different. Therefore, based on the unit time, the locking mechanism locks the grinding beads that fell to the bottom of the test tube before the unit time, so that the grinding beads in the test tube after the tissue sample is fully ground no longer grind the tissue sample particles, thereby avoiding excessive grinding of the test tube solution. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 It is a schematic diagram of the structure of the present invention;
[0023] Figure 2 This is a schematic diagram of the structure of the inner wall of the box cover of the present invention when viewed from above;
[0024] Figure 3 This is a schematic diagram of the front and cross-sectional structure of the limit cover of the present invention;
[0025] Figure 4 for Figure 3 Enlarged schematic diagram of area A in the middle;
[0026] Figure 5 This is a schematic diagram of the cross-sectional structure of a local placement groove of the present invention;
[0027] Figure 6 for Figure 5 Enlarged schematic diagram of area B in the middle;
[0028] Figure 7 It is a schematic diagram of the partial separation state of the winding reel 1 and the winding reel 2 of the present invention;
[0029] Figure 8 for Figure 7 Enlarged schematic diagram of the middle C area;
[0030] Fig. 9 This is a schematic diagram of the top view of the placement plate of the present invention;
[0031] Fig.10 This is a schematic diagram of the structure of the placement plate of the present invention when viewed from above.
[0032] In the figure: 1. grinder chassis; 2. transmission shaft; 3. placement plate; 4. placement slot; 5. threaded rod; 6. upper cover; 7. limit cover; 8. locking mechanism; 80. strong magnetic block; 81. sliding slot; 82. moving rod; 83. electromagnet; 84. moving part; 85. barrier; 86. iron block; 87. transmission slot; 88. elastic rope; 89. push rod; 810. transmission tube; 811. bead chain; 812. magnetic field shielding plate; 813. moving slot; 814. reset spring; 815. transmission part; 816. transmission rope; 817. winding reel 1; 818. winding reel 2; 819. connecting rope; 9. regulating mechanism; 90. trigger rod; 91. baffle; 92. infrared distance sensor; 10. box body; 11. box cover. DETAILED DESCRIPTION
[0033] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0034] Embodiment 1
[0035] See also Figures 1 to 10 The present invention provides a technical solution: a laboratory sample tissue grinder, including a grinder chassis 1 and a transmission shaft 2; also including a placement plate 3, the placement plate 3 is fixed on the outside of the transmission shaft 2, a plurality of placement grooves 4 are opened on the surface of the placement plate 3, the placement grooves 4 are used to place test tubes, and the transmission shaft 2 is fixedly connected with a threaded rod 5 at one end close to the placement plate 3; an upper cover plate 6, the upper cover plate 6 is slidably connected to the threaded rod 5, and a limit cover 7 is threadedly connected between the limit cover 7 and the threaded rod 5; a locking mechanism 8, the locking mechanism 8 is located at the outside of the plurality of placement grooves 4, each time the placement plate 3 moves downward in the vertical direction, the locking mechanism 8 locks the grinding beads that fall into the bottom of the test tube per unit time; a regulating mechanism 9, the regulating mechanism 9 is connected to the limit cover 7, and the regulating mechanism 9 adjusts the unit time duration of the locking mechanism 8 during the working process according to the height of the test tube placed in the placement plate 3.
[0036] During use, the testing personnel place the test tube containing the sample tissue and grinding beads into the placement groove 4. After all the test tubes are placed, the upper cover 6 is snapped onto the top of the test tube, and the upper cover 6 is fixed by screwing the limit cover 7 into the surface of the threaded rod 5. The height of the test tube placed in the placement tray 3 is detected by the set regulating mechanism 9, and the unit time duration of the locking mechanism 8 during the working process is adjusted according to the height of the test tube. When grinding tissues in test tubes of different heights, the locking mechanism 8 can lock the grinding beads in the test tube that have been fully ground, so as to avoid excessive grinding of the tissues in the test tube and affect the experimental results.
[0037] When grinding begins, the driving part in the grinder case 1 drives the transmission shaft 2 to rotate, and regularly drives the transmission shaft 2 to move upward or downward in the vertical direction. The transmission shaft 2 drives the placement plate 3 to rotate and move upward or downward in the vertical direction, so that the grinding beads in the test tube move centrifugally and move up and down in the test tube, thereby grinding and crushing the large tissue sample in the test tube.
[0038] Each time the placement plate 3 moves downward in the vertical direction, the grinding beads in the test tube will move relative to the test tube due to inertia, causing the grinding beads to be located at the top of the test tube. When the grinding beads are located at the top of the test tube, although the transmission shaft 2 drives the placement plate 3 to rotate, the grinding beads will slide downward in the test tube under the action of their own gravity. The tissue samples in the test tube are ground to different degrees. The tissue samples that are not fully ground remain in large blocks or clumps, and the fiber network formed by the connective tissue will hinder the falling of the grinding beads, while the tissue samples that are fully ground have been ground into smaller particles or powders, and these particles or powders have a greater hindering effect on the falling of the grinding beads. The falling time of the grinding beads in the fully ground sample tissue test tube is different from that in the incompletely ground test tube. According to the falling time of the grinding beads in the fully ground sample tissue test tube as the unit time, the time for the grinding beads to fall on the top of the test tubes at different heights is also different. Therefore, according to the unit time, the locking mechanism 8 locks the grinding beads that have fallen to the bottom of the test tube before the unit time, so that the grinding beads in the test tube after the tissue sample is fully ground no longer grind the tissue sample particles, while the grinding beads in the incompletely ground test tube still move relative to the inner wall of the test tube to cooperate with the grinding and crushing of the connective tissue in the test tube, thereby avoiding excessive grinding of the test tube solution.
[0039] The locking mechanism 8 includes a plurality of strong magnetic blocks 80, the number of which is the same as the number of placement slots 4. Each strong magnetic block 80 is located below the corresponding placement slot 4. A sliding slot 81 is provided on the inner wall of the placement disk 3 to be slidably connected to the strong magnetic block 80. A moving rod 82 is fixedly connected to the bottom of the strong magnetic block 80. The moving rod 82 is slidably connected to the inner wall of the placement disk 3. An electromagnet 83 is provided below the placement disk 3. The electromagnet 83 is fixedly connected to the inner wall of the grinder chassis 1. A moving part 84 is provided on the inner wall of the placement disk 3 to push the moving rod 82 to move when the electromagnet 83 is energized. A blocking part 85 is provided on the inner wall of the sliding slot 81 to block the magnetic field. The blocking part 85 releases the blocking of the magnetic field when the strong magnetic block 80 moves upward.
[0040] Each time the placement plate 3 moves downward in the vertical direction, the regulating mechanism 9 controls the power-on time of the electromagnet 83 according to the test tube height. The time is the time required for the grinding beads to fall freely from the top of the test tube to the bottom of the test tube when the tissue sample in the test tube is fully ground. The time consumed by the grinding beads to fall is inconsistent for test tubes at different heights. Therefore, the power-on time of the electromagnet 83 is also different for test tubes at different heights. The electromagnet 83 generates a magnetic field when it is energized. At this time, the moving member 84 pushes the moving rod 82 to move upward, and the moving rod 82 drives the strong magnetic block 80 to slide upward on the inner wall of the sliding groove 81. When the strong magnetic block 80 moves, it drives the blocking member 85 out of the sliding groove 81, so that the strong magnetic block 80 is close to the bottom of the placement groove 4. Since stainless steel beads are usually used when grinding tissue samples, the magnetic field generated by the strong magnetic block 80 adsorbs the grinding beads that fall to the bottom of the test tube per unit time, while the grinding beads that fail to fall to the bottom of the test tube due to insufficient grinding of tissue samples and obstruction of connective tissue are less adsorbed by the magnetic field.
[0041] After the estimated time is over, the electromagnet 83 is powered off and no longer acts on the moving part 84. At this time, the moving part 84 will generate a downward traction force on the moving rod 82, and when the strong magnetic block 80 attracts the grinding beads, the grinding beads will also generate an equal reverse force on the strong magnetic block 80, that is, the closer the grinding beads are to the strong magnetic block 80, the greater the force of the grinding beads on the strong magnetic block 80. Therefore, the force of the grinding beads at the bottom of the test tube on the strong magnetic block 80 makes it impossible for the moving part 84 to drive the strong magnetic block 80 to reset, and the grinding beads not at the bottom of the test tube are The force of the strong magnetic block 80 is small, and the moving part 84 will drive the strong magnetic block 80 to reset. When the strong magnetic block 80 is reset, the blocking part 85 is reset to block the effect of the magnetic field of the strong magnetic block 80 on the grinding beads in the test tube, so that every time the placement plate 3 moves downward in the vertical direction, the grinder will detect the grinding state of the tissue sample in the test tube and lock the grinding beads in the test tube that have been fully ground, so as to prevent the grinding beads from continuing to make centrifugal motion in the test tube as the placement plate 3 rotates, resulting in excessive grinding of the tissue sample in the test tube, affecting experimental observation.
[0042] The moving part 84 includes an iron block 86 that is slidably connected to the inner wall of the placement plate 3. The inner wall of the placement plate 3 is provided with a transmission groove 87 that is slidably connected to the iron block 86. The upper end of the iron block 86 is fixedly connected to an elastic rope 88, and the elastic rope 88 is fixed to the inner wall of the transmission groove 87. The lower end of the iron block 86 is fixedly connected to a push rod 89. A transmission pipe 810 is connected between the transmission groove 87 and the sliding groove 81. The push rod 89 and the moving rod 82 are respectively slidably connected to the inner wall of the transmission pipe 810. The inner wall of the transmission pipe 810 is provided with a bead chain 811, and the two ends of the bead chain 811 are respectively fixed to the moving rod 82 and the push rod 89.
[0043] When the electromagnet 83 is energized, the magnetic field generated by the electromagnet 83 attracts the iron block 86 in the transmission groove 87 to move downward, and the iron block 86 stretches the elastic rope 88. At the same time, the downward movement of the iron block 86 drives the push rod 89 to slide downward along the inner wall of the transmission groove 87 and insert into the inner wall of the transmission tube 810. When the push rod 89 slides along the inner wall of the transmission rod, it squeezes the bead chain 811 on the inner wall of the transmission tube 810. The bead chain 811 is composed of a plurality of beads connected in series. Through the mutual squeezing of the beads between the bead chain 811, the moving rod 82 is pushed to slide upward on the inner wall of the transmission tube 810. The upward movement of the moving rod 82 pushes the strong magnetic block 80 to move upward on the inner wall of the sliding groove 81 to cooperate with the attraction of the grinding beads at the bottom of the test tube.
[0044] When the electromagnet 83 is powered off, if the grinding beads are not at the bottom of the test tube, the force exerted by the grinding beads on the strong magnetic block 80 is less than the elastic force generated by the stretching of the elastic rope 88, so that the elastic rope 88 drives the iron block 86 to reset, and the iron block 86 drives the push rod 89 to slide upward, and the push rod 89 pulls the bead chain 811 to slide on the inner wall of the transmission tube 810, and the bead chain 811 pulls the moving rod 82 to move downward, and the moving rod 82 drives the strong magnetic block 80 to slide downward along the inner wall of the sliding groove 81, so that the strong magnetic block 80 is away from the test tube.
[0045] If the grinding beads are at the bottom of the test tube, the force exerted by the grinding beads on the strong magnetic block 80 is greater than the elastic force generated by the stretching of the elastic rope 88, so that the elastic rope 88 cannot pull the iron block 86 to reset. The force exerted by the strong magnetic block 80 on the grinding beads locks the grinding beads at the bottom of the test tube. The grinding beads in the test tube will no longer continue to grind the tissue sample in the test tube as the placement plate 3 rotates and vibrates up and down, thereby avoiding excessive grinding of the tissue sample solution.
[0046] The barrier 85 includes a magnetic field shielding plate 812 located on the inner wall of the sliding groove 81. The magnetic field shielding plate 812 is made of a high magnetic permeability material, such as iron, nickel, cobalt and alloys thereof. The thickness of the magnetic field shielding plate 812 is smaller than that of the strong magnetic block 80. A moving groove 813 slidably connected to the magnetic field shielding plate 812 is provided on the inner wall of the placement plate 3. A return spring 814 is fixedly connected to the side of the magnetic field shielding plate 812. The return spring 814 is slidably connected to the inner wall of the moving groove 813. A transmission member 815 is provided between the magnetic field shielding plate 812 and the strong magnetic block 80.
[0047] High magnetic permeability materials are key materials in magnetic field shielding, and their magnetic permeability is much higher than that of ordinary materials. The principle of shielding magnetic field is: when high magnetic permeability materials such as iron are placed in a magnetic field, due to the high magnetic permeability of the material, the magnetic lines of force will preferentially pass through the inside of the material instead of bypassing it. In this way, the magnetic lines of force are guided into the inside of the material, thereby reducing the magnetic field strength in the external space. When the present application is in use, the strong magnetic block 80 is far away from the bottom of the test tube in the initial state, and there is a magnetic field shielding plate 812 made of high magnetic permeability material between the strong magnetic block 80 and the bottom of the test tube, so that part of the magnetic field generated by the strong magnetic block 80 is weakened by the distance, and part is guided into the inside of the material, thereby weakening the attraction of the strong magnetic block 80 to the grinding beads in the test tube when it is not close to the bottom of the test tube.
[0048] When the strong magnetic block 80 slides upward along the inner wall of the sliding groove 81, the strong magnetic block 80 drives the transmission member 815 to work, and the transmission member 815 drives the magnetic field shielding plate 812 to slide along the inner wall of the movable groove 813. The magnetic field shielding plate 812 squeezes the reset spring 814, so that the strong magnetic block 80 can slide to the top of the sliding groove 81. At this time, the distance between the strong magnetic block 80 and the test tube is the shortest.
[0049] If the grinding beads are not at the bottom of the test tube, at this time, the force exerted by the grinding beads on the strong magnetic block 80 is smaller than the elastic force generated by the stretching of the elastic rope 88, so that when the elastic rope 88 drives the iron block 86 to reset, the strong magnetic block 80 slides downward along the inner wall of the sliding groove 81, and when the top of the strong magnetic block 80 slides to the bottom of the magnetic field shielding plate 812, the return spring 814 in a compressed state pushes the magnetic field shielding plate 812 to reset, so that when the strong magnetic block 80 is reset, the magnetic field shielding plate 812 is blocked between the test tube and the strong magnetic block 80 again.
[0050] If the grinding beads are at the bottom of the test tube, the force exerted by the grinding beads on the strong magnetic block 80 is greater than the elastic force generated by the stretching of the elastic rope 88, so that the elastic rope 88 cannot pull the iron block 86 to reset. The return spring 814 in a compressed state pushes the magnetic field shielding plate 812 to squeeze the side of the strong magnetic block 80.
[0051] The transmission member 815 includes a transmission rope 816 fixedly connected to the magnetic field shielding plate 812, the transmission rope 816 is slidably connected to the inner wall of the placement disk 3, the end of the transmission rope 816 away from the magnetic field shielding plate 812 is fixedly connected to a winding disk 1 817, the winding disk 1 817 is rotatably connected to the inner wall of the placement disk 3, the inner wall of the placement disk 3 is rotatably connected to a winding disk 2 818, the diameter of the winding disk 1 817 is larger than the diameter of the winding disk 2 818, so that when the strong magnetic block 80 moves to the bottom end of the magnetic field shielding plate 812, the magnetic field shielding plate 812 slides out of the sliding groove 81, the winding disk 2 818 is coaxial with the winding disk 1 817, and a connecting rope 819 is wound on the outer side of the winding disk 2 818, and the end of the connecting rope 819 away from the winding disk 2 818 is fixed to the bottom of the strong magnetic block 80.
[0052] When the strong magnetic block 80 slides upward along the inner wall of the sliding groove 81, the strong magnetic block 80 moves to drive the connecting rope 819, and the connecting rope 819 drives the winding disk 2 818 to rotate, and releases the connecting rope 819 wrapped around the winding disk 2 818. Since the winding disk 2 818 is coaxial with the winding disk 1 817, when the winding disk 2 818 rotates, the winding disk 1 817 rotates, and the winding disk 1 817 rotates to reel in the transmission rope 816. After the transmission rope 816 is reeled in, it pulls the magnetic field shielding plate 812, so that the magnetic field shielding plate 812 slides on the inner wall of the moving groove 813 and squeezes the reset spring 814.
[0053] When the strong magnetic block 80 slides downward along the inner wall of the sliding groove 81, the return spring 814 in a compressed state pushes the magnetic field shielding plate 812 to slide along the inner wall of the moving groove 813, and blocks the test tube and the strong magnetic block 80. When the magnetic field shielding plate 812 moves, it pulls the transmission rope 816, and the transmission rope 816 drives the winding reel 1 817 to rotate in the opposite direction, so that the connecting rope 819 wrapped around the outside of the winding reel 1 817 is released, and the winding reel 1 817 drives the winding reel 2 818 to reverse, and the winding reel 2 818 rotates to rewind the connecting rope 819 to cooperate with the reset of the strong magnetic block 80.
[0054] The regulating mechanism 9 includes a trigger rod 90 which is slidably connected to the inner wall of the limit cover 7. One end of the trigger rod 90 which is connected to the outside is fixedly connected to a baffle 91. The grinder chassis 1 includes a box body 10 and a box cover 11. The box cover 11 is hinged to the box body 10. An infrared distance sensor 92 for detecting the movement of the baffle 91 is installed on the inner wall of the box cover 11. The infrared distance sensor 92 is connected to the electromagnet 83.
[0055] When fixing the test tube, the inspector engages the upper cover 6 on the top of the test tube and then screws the limit cover 7 into the threaded rod 5. As the limit cover 7 presses the upper cover 6 against the top of the test tube, the threaded rod 5 pushes the trigger rod 90, so that the greater the distance that the limit cover 7 is screwed into the threaded rod 5, the longer the trigger rod 90 is extended, and the greater the distance that the trigger rod 90 drives the baffle 91 to move. When the inspector closes the box cover 11, the infrared distance sensor 92 in the box cover 11 detects the distance between the baffle 91 and the infrared distance sensor 92. The infrared distance sensor 92 is a mature existing technology on the market. Test tubes of different heights correspond to different distances between the baffle 91 and the infrared distance sensor 92. The infrared distance sensor 92 processes the detected distance information and sends it to the electromagnet 83, thereby controlling the power-on time of the electromagnet 83.
[0056] Embodiment 2
[0057] In the second embodiment, other structures remain unchanged. The difference from the first embodiment is that the baffle 91 is in an inverted concave shape, and the baffle 91 is slidably connected to the inner wall of the limit cover 7, so that when the baffle 91 is pushed by the trigger rod 90, the two sides of the baffle 91 are always inserted into the inner wall of the limit cover 7, thereby ensuring the stability of the baffle 91 when it rotates.
[0058] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.
[0059] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A sample tissue grinder for a laboratory, comprising: A grinding machine housing (1) and a transmission shaft (2); The invention is characterized in that: it also comprises a placement plate (3), the placement plate (3) is fixed on the outside of the transmission shaft (2), a plurality of placement grooves (4) are provided on the surface of the placement plate (3), the placement grooves (4) are used to place test tubes, and a threaded rod (5) is fixedly connected to one end of the transmission shaft (2) close to the placement plate (3); An upper cover plate (6), wherein the upper cover plate (6) is slidably connected to the threaded rod (5); A limit cover (7), wherein the limit cover (7) is threadedly connected to the threaded rod (5); A locking mechanism (8), the locking mechanism (8) being located outside the plurality of placement slots (4), and each time the placement plate (3) moves downward in the vertical direction, the locking mechanism (8) locks the grinding beads that fall into the bottom of the test tube within a unit time; A regulating mechanism (9), the regulating mechanism (9) being connected to the limiting cover (7), and the regulating mechanism (9) adjusting the unit time duration of the locking mechanism (8) during the working process according to the height of the test tube placed in the placing plate (3); The locking mechanism (8) comprises a plurality of strong magnetic blocks (80), the number of the strong magnetic blocks (80) being the same as the number of the placement slots (4), each of the strong magnetic blocks (80) being located below the corresponding placement slot (4), the inner wall of the placement plate (3) being provided with a sliding slot (81) slidably connected to the strong magnetic block (80), the bottom of the strong magnetic block (80) being fixedly connected to a moving rod (82), the moving rod (82) being slidably connected to the inner wall of the placement plate (3), an electromagnet (83) being provided below the placement plate (3), the electromagnet (83) being fixedly connected to the inner wall of the grinding machine case (1), the inner wall of the placement plate (3) being provided with a moving part (84) for pushing the moving rod (82) to move when the electromagnet (83) is energized, the inner wall of the sliding slot (81) being provided with a blocking part (85) for blocking a magnetic field, the blocking part (85) releasing the blocking of the magnetic field when the strong magnetic block (80) moves upward.
2. The laboratory sample tissue grinder according to claim 1, characterized in that: The moving member (84) comprises an iron block (86) slidably connected to the inner wall of the placement plate (3); the inner wall of the placement plate (3) is provided with a transmission groove (87) slidably connected to the iron block (86); an elastic rope (88) is fixedly connected to the upper end of the iron block (86); the elastic rope (88) is fixedly connected to the inner wall of the transmission groove (87); a push rod (89) is fixedly connected to the lower end of the iron block (86); a transmission tube (810) is connected between the transmission groove (87) and the sliding groove (81); the push rod (89) and the moving rod (82) are respectively slidably connected to the inner wall of the transmission tube (810); a bead chain (811) is provided on the inner wall of the transmission tube (810); two ends of the bead chain (811) are respectively fixed to the moving rod (82) and the push rod (89).
3. The laboratory sample tissue grinder according to claim 1, characterized in that: The blocking member (85) comprises a magnetic field shielding plate (812) located on the inner wall of the sliding groove (81); the inner wall of the placement plate (3) is provided with a moving groove (813) slidably connected to the magnetic field shielding plate (812); a return spring (814) is fixedly connected to the side of the magnetic field shielding plate (812); the return spring (814) is slidably connected to the inner wall of the moving groove (813); and a transmission member (815) is provided between the magnetic field shielding plate (812) and the strong magnetic block (80).
4. The laboratory sample tissue grinder according to claim 3, characterized in that: The magnetic field shielding plate (812) is made of a high magnetic permeability material, and is made of iron, nickel, cobalt and alloy materials thereof.
5. The laboratory sample tissue grinder according to claim 3, characterized in that: The thickness of the magnetic field shielding plate (812) is smaller than the thickness of the strong magnetic block (80).
6. The laboratory sample tissue grinder according to claim 3, characterized in that: The transmission member (815) comprises a transmission rope (816) fixedly connected to the magnetic field shielding plate (812), the transmission rope (816) being slidably connected to the inner wall of the placement disk (3), the transmission rope (816) being fixedly connected to a winding disk 1 (817) at one end away from the magnetic field shielding plate (812), the winding disk 1 (817) being rotationally connected to the inner wall of the placement disk (3), the inner wall of the placement disk (3) being rotationally connected to a winding disk 2 (818), the winding disk 2 (818) being coaxial with the winding disk 1 (817), a connecting rope (819) being wound on the outer side of the winding disk 2 (818), and the connecting rope (819) being fixed to the bottom of the strong magnetic block (80) at one end away from the winding disk 2 (818).
7. The laboratory sample tissue grinder according to claim 6, characterized in that: The diameter of the winding reel 1 (817) is larger than the diameter of the winding reel 2 (818).
8. The laboratory sample tissue grinder according to claim 1, characterized in that: The regulating mechanism (9) comprises a trigger rod (90) slidably connected to the inner wall of the limit cover (7); one end of the trigger rod (90) communicating with the outside is fixedly connected to a baffle (91); the grinding machine case (1) comprises a case body (10) and a case cover (11); the case cover (11) is hinged to the case body (10); an infrared distance sensor (92) for detecting the movement amount of the baffle (91) is installed on the inner wall of the case cover (11); and the infrared distance sensor (92) is connected to the electromagnet (83).
9. The laboratory sample tissue grinder according to claim 8, characterized in that: The baffle plate (91) is in an inverted concave shape, and the baffle plate (91) is slidably connected to the inner wall of the limiting cover (7).
Citation Information
Patent Citations
Intelligent magnetic frame with adjustable position
CN103394410A