Implantable wireless monitor for monitoring portal vein blood pressure

Abstract

The invention discloses an implantable wireless monitor for monitoring portal vein blood pressure, and relates to the field of blood pressure monitoring, the implantable wireless monitor for monitoring portal vein blood pressure comprises a pressure detection part, a signal processing module and an upper computer; the pressure detection component is implanted into the portal vein of a patient and connected with the signal processing module, and the pressure detection component is used for detecting the pressure in the portal vein in real time and sending a pressure signal in the portal vein to the signal processing module in real time; the signal processing module is implanted into subcutaneous tissue of a patient, is in wireless connection with the upper computer, and is used for processing the pressure signal in the portal vein to obtain pressure data in the portal vein and sending the pressure data in the portal vein to the upper computer in a wireless mode; the upper computer is used for displaying the pressure data in the portal vein in real time so as to monitor the portal vein blood pressure of a patient in real time. The portal vein pressure can be continuously and accurately monitored in real time.

Description

Technical Field

[0001] The present application relates to the field of blood pressure monitoring, and in particular to an implantable wireless monitor for monitoring portal vein blood pressure. Background Art

[0002] Portal hypertension is a clinical syndrome of increased portal venous system pressure caused by multiple factors, which is common in patients with liver cirrhosis. Traditional portal vein pressure monitoring methods such as percutaneous transhepatic puncture and hepatic venous pressure gradient measurement are invasive, high-risk, and difficult to repeat, which limits their application in clinical practice. Summary of the invention

[0003] The purpose of the present application is to provide an implantable wireless monitor for monitoring portal vein blood pressure, which can monitor portal vein pressure in real time, continuously and accurately.

[0004] To achieve the above objectives, this application provides the following solutions:

[0005] The present application provides an implantable wireless monitor for monitoring portal vein blood pressure, comprising: a pressure detection component, a signal processing module and a host computer;

[0006] The pressure detection component is implanted in the patient's portal vein and connected to the signal processing module. The pressure detection component is used to detect the pressure in the portal vein in real time and send the pressure signal in the portal vein to the signal processing module in real time;

[0007] The signal processing module is implanted in the subcutaneous tissue of the patient and is wirelessly connected to the host computer. The signal processing module is used to process the pressure signal in the portal vein to obtain the pressure data in the portal vein, and send the pressure data in the portal vein to the host computer in a wireless manner;

[0008] The host computer is used to display the pressure data in the portal vein in real time to monitor the patient's portal vein blood pressure in real time.

[0009] Optionally, the pressure detection component includes a hemispherical head, a groove and a pressure sensor chip;

[0010] The groove is fixed to the hemispherical head; and the pressure sensor chip is located in the groove.

[0011] Optionally, the hemispherical head is made of biocompatible glue.

[0012] Optionally, the groove is a metal U-shaped groove.

[0013] Optionally, the pressure sensor chip is connected to the metal below the groove through a sensor protective adhesive.

[0014] Optionally, the pressure sensor chip is a piezoresistive sensor with a half-bridge structure.

[0015] Optionally, the implantable wireless monitor for monitoring portal vein blood pressure further includes an insulated flexible wire; the pressure detection component is connected to the signal processing module via the insulated flexible wire.

[0016] Optionally, the signal processing module is a flexible circuit board.

[0017] Optionally, the signal processing module includes a power supply circuit and a signal amplification circuit, a filtering circuit, an analog-to-digital conversion circuit and a wireless transmission circuit connected in sequence; the power supply circuit is connected to the signal amplification circuit, the filtering circuit, the analog-to-digital conversion circuit and the wireless transmission circuit respectively;

[0018] The signal amplifying circuit is also connected to the pressure detecting component to receive the pressure signal in the portal vein and amplify the pressure signal in the portal vein to obtain an amplified signal;

[0019] The filtering circuit is used to filter the amplified signal to obtain a filtered signal;

[0020] The analog-to-digital conversion circuit is used to convert the filtered signal into a digital signal to obtain pressure data in the portal vein;

[0021] The wireless transmission circuit is also connected to the host computer to send the pressure data in the portal vein to the host computer.

[0022] Optionally, the host computer displays the pressure data in the portal vein in a waveform.

[0023] According to the specific embodiments provided in this application, this application discloses the following technical effects:

[0024] The present application provides an implantable wireless monitor for monitoring portal vein blood pressure. By implanting a pressure detection component in the patient's portal vein, the pressure changes in the portal vein can be monitored in real time and accurately. The signal processing module is implanted in the patient's subcutaneous tissue and will not affect the normal blood flow. The pressure data in the portal vein is sent to a host computer wirelessly, making data collection and monitoring more convenient, reducing the patient's pain and the workload of medical staff. The pressure data in the portal vein is displayed in real time on the host computer, thereby realizing real-time, continuous and accurate monitoring of the portal vein pressure. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0026] Figure 1 A schematic diagram of the overall structure of an implantable wireless monitor for monitoring portal vein blood pressure provided in one embodiment of the present application;

[0027] Figure 2 A schematic diagram of the connection between a pressure detection component and a signal processing module provided in one embodiment of the present application;

[0028] Figure 3 A schematic diagram of a pressure detection component provided in an embodiment of the present application;

[0029] Figure 4 A schematic diagram of an implantable wireless monitor for monitoring portal blood pressure provided by an embodiment of the present application.

[0030] Description of reference numerals:

[0031] 1-pressure detection component, 2-signal processing module, 3-host computer, 4-hemispherical head, 5-groove, 6-pressure sensor chip, 7-insulated flexible wire, 8-sensor protective glue, 9-power supply circuit, 10-signal amplification circuit, 11-filtering circuit, 12-analog-to-digital conversion circuit, 13-wireless transmission circuit. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0033] The present application combines microchips and wireless transmission technology to achieve real-time, continuous and accurate monitoring of portal vein pressure through implantation, overcoming the limitations of traditional methods.

[0034] In order to make the above-mentioned objects, features and advantages of the present application more obvious and easy to understand, the present application is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0035] In an exemplary embodiment, Figure 1 and Figure 2As shown, an implantable wireless monitor for monitoring portal vein blood pressure is provided, comprising: a pressure detection component 1, a signal processing module 2 and a host computer 3.

[0036] The pressure detection component 1 is implanted in the patient's portal vein and connected to the signal processing module 2. The pressure detection component 1 is used to detect the pressure in the portal vein in real time and send the pressure signal in the portal vein to the signal processing module 2 in real time.

[0037] After puncturing the right branch of the portal vein, the pressure detection component 1 moves along the blood vessel until it reaches the main trunk of the portal vein, and measures the pressure against the blood flow.

[0038] Preferably, if Figures 1 to 3 As shown, the pressure detection component 1 includes a hemispherical head 4, a groove 5 and a pressure sensor chip 6. The groove 5 is fixed to the hemispherical head 4. The pressure sensor chip 6 is located in the groove 5.

[0039] The hemispherical head 4 is used to reduce the resistance of puncturing into the portal vein, and the hemispherical head 4 can reduce stress concentration by dispersing the stress in the pipeline, thereby protecting the pipeline system.

[0040] In a specific example, the material of the hemispherical head 4 is a biocompatible glue. The groove 5 is a metal U-shaped groove. The metal U-shaped groove is used to place the pressure sensor chip 6 and the sensor protective glue 8. The pressure sensor chip 6 is connected to the metal below the groove 5 through the sensor protective glue 8. The sensor protective glue 8 is biocompatible, does not cause the function of cells and tissues to decline, does not cause inflammation, canceration, and rejection reactions in tissues, does not cause the formation of thrombus, and does not affect the normal flow of blood in veins. The sensor protective glue 8 is used to protect and firmly bond the pressure sensor chip 6, and reduce the relative movement of the pressure sensor chip 6 relative to the hemispherical head 4.

[0041] The pressure sensor chip 6 is a piezoresistive sensor with a half-bridge structure. The chip is made based on the piezoresistive effect of silicon material, and is a silicon chip with a thin etched diaphragm. The diaphragm will bend under the action of pressure, thereby causing a change in the resistance value. The pressure sensor chip works stably and is compact.

[0042] Furthermore, the implantable wireless monitor for monitoring portal vein blood pressure further comprises an insulated flexible wire 7. The pressure detection component 1 is connected to the signal processing module 2 via the insulated flexible wire 7.

[0043] The signal processing module 2 is implanted in the patient's subcutaneous tissue and is wirelessly connected to the host computer 3. The signal processing module 2 is used to process the pressure signal in the portal vein, obtain the pressure data in the portal vein, and send the pressure data in the portal vein to the host computer 3 wirelessly.

[0044] In a specific example, the signal processing module 2 is a flexible circuit board, which is implanted in the subcutaneous tissue of the chest and transmits signals to the host computer 3 via Bluetooth. The signal processing module 2 is only implanted in the subcutaneous tissue of the chest, so it will not affect the normal flow of blood.

[0045] like Figure 4 As shown, the signal processing module 2 includes a power supply circuit 9 and a signal amplifying circuit 10, a filtering circuit 11, an analog-to-digital conversion circuit 12 and a wireless transmission circuit 13 connected in sequence. The power supply circuit 9 is connected to the signal amplifying circuit 10, the filtering circuit 11, the analog-to-digital conversion circuit 12 and the wireless transmission circuit 13 respectively.

[0046] The power supply circuit 9 uses a lithium battery to supply power to the signal amplification circuit 10 , the filter circuit 11 , the analog-to-digital conversion circuit 12 and the wireless transmission circuit 13 .

[0047] The signal amplifying circuit 10 is also connected to the pressure detecting component 1 to receive the pressure signal in the portal vein and amplify the pressure signal in the portal vein to obtain an amplified signal.

[0048] The filtering circuit 11 is used to filter the amplified signal to obtain a filtered signal.

[0049] The analog-to-digital conversion circuit 12 is used to convert the filtered signal into a digital signal to obtain pressure data in the portal vein.

[0050] The wireless transmission circuit 13 is also connected to the host computer 3 to send the pressure data in the portal vein to the host computer 3 .

[0051] The host computer 3 is used to display the pressure data in the portal vein in real time, so as to monitor the portal vein blood pressure of the patient in real time.

[0052] Specifically, the host computer 3 displays the pressure data in the portal vein in a waveform manner, that is, the host computer 3 receives the portal vein pressure data sent by the Bluetooth host through the serial port and realizes the display of the real-time waveform of the pressure signal.

[0053] Furthermore, the host computer 3 is also used to determine in real time whether the blood pressure in the portal vein exceeds the standard according to the pressure data in the portal vein, and to issue an alarm when it exceeds the standard so as to intervene in time.

[0054] In summary, the working process of the implantable wireless monitor for monitoring portal vein blood pressure is as follows: the pressure sensor chip 6 detects the pressure in the portal vein in real time, and transmits the pressure signal to the signal processing module 2 through the insulated flexible wire 7. The signal processing module 2 compensates, amplifies, filters and performs digital-to-analog conversion on the pressure signal. The processed digital signal is transmitted to the host computer 3 through the wireless module, and the pressure change is displayed in real time.

[0055] The implantable wireless monitor for monitoring portal vein blood pressure provided in the present application can monitor the portal vein blood pressure of patients during surgery, and can also monitor the venous blood pressure of patients in real time during their daily lives.

[0056] This application can monitor the pressure changes of the portal vein in real time by implanting a micro pressure sensor chip in the patient's portal vein, and can promptly respond to changes in the patient's condition. The pressure sensor chip 6 has been precisely calibrated, has high sensitivity, and has small temperature drift and humidity drift, which ensures the accuracy of the measured data. The pressure sensor chip 6 transmits the pressure signal to the signal processing module 2, and after signal processing, it is wirelessly transmitted to the host computer 3 via Bluetooth for real-time display and recording. The wireless transmission function makes data collection and monitoring more convenient, reducing the patient's pain and the workload of medical staff. The host computer 3 can not only display continuous blood pressure data, but also issue an alarm when blood pressure exceeds the standard, which is convenient for timely intervention.

[0057] It should be noted that the user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data used for analysis, stored data, displayed data, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties, and the collection, use and processing of relevant data must comply with relevant regulations.

[0058] The technical features of the above embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0059] This article uses specific examples to illustrate the principles and implementation methods of this application. The description of the above embodiments is only used to help understand the method and core ideas of this application. At the same time, for those skilled in the art, according to the ideas of this application, there will be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as limiting this application.

Claims

1. An implantable wireless monitor for monitoring portal blood pressure, characterized in that: The implantable wireless monitor for monitoring portal vein blood pressure comprises: a pressure detection component, a signal processing module and a host computer; The pressure detection component is implanted in the patient's portal vein and connected to the signal processing module. The pressure detection component is used to detect the pressure in the portal vein in real time and send the pressure signal in the portal vein to the signal processing module in real time; The signal processing module is implanted in the subcutaneous tissue of the patient and is wirelessly connected to the host computer. The signal processing module is used to process the pressure signal in the portal vein to obtain the pressure data in the portal vein, and send the pressure data in the portal vein to the host computer in a wireless manner; The host computer is used to display the pressure data in the portal vein in real time to monitor the patient's portal vein blood pressure in real time.

2. The implantable wireless monitor for monitoring portal blood pressure according to claim 1, characterized in that: The pressure detection component includes a hemispherical head, a groove and a pressure sensor chip; The groove is fixed to the hemispherical head; and the pressure sensor chip is located in the groove.

3. The implantable wireless monitor for monitoring portal blood pressure according to claim 2, characterized in that: The material of the hemispherical head is biocompatible glue.

4. The implantable wireless monitor for monitoring portal blood pressure according to claim 2, characterized in that: The groove is a metal U-shaped groove.

5. The implantable wireless monitor for monitoring portal blood pressure according to claim 4, characterized in that: The pressure sensor chip is connected to the metal below the groove through a sensor protection glue.

6. The implantable wireless monitor for monitoring portal blood pressure according to claim 2, characterized in that: The pressure sensor chip is a piezoresistive sensor with a half-bridge structure.

7. The implantable wireless monitor for monitoring portal blood pressure according to claim 1, characterized in that: The implantable wireless monitor for monitoring portal vein blood pressure also includes an insulated flexible wire; the pressure detection component is connected to the signal processing module via the insulated flexible wire.

8. The implantable wireless monitor for monitoring portal blood pressure according to claim 1, characterized in that: The signal processing module is a flexible circuit board.

9. The implantable wireless monitor for monitoring portal blood pressure according to claim 1, characterized in that: The signal processing module includes a power supply circuit and a signal amplification circuit, a filtering circuit, an analog-to-digital conversion circuit and a wireless transmission circuit connected in sequence; the power supply circuit is connected to the signal amplification circuit, the filtering circuit, the analog-to-digital conversion circuit and the wireless transmission circuit respectively; The signal amplifying circuit is also connected to the pressure detecting component to receive the pressure signal in the portal vein and amplify the pressure signal in the portal vein to obtain an amplified signal; The filtering circuit is used to filter the amplified signal to obtain a filtered signal; The analog-to-digital conversion circuit is used to convert the filtered signal into a digital signal to obtain pressure data in the portal vein; The wireless transmission circuit is also connected to the host computer to send the pressure data in the portal vein to the host computer.

10. The implantable wireless monitor for monitoring portal blood pressure according to claim 1, characterized in that: The host computer displays the pressure data in the portal vein in a waveform manner.

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