Lesion cell collector and cold chain transfer device thereof

Abstract

The invention relates to a pathological cell collector and a cold chain transfer device thereof, and belongs to the technical field of medical detection. The cell collector comprises a bottom shell, an umbrella-shaped outer membrane, a top shell, a wrapping membrane and a pull rope. The umbrella-shaped outer film is arranged between the bottom shell and the top shell, the small end of the umbrella-shaped outer film is fixedly connected with the bottom shell, and the large end of the umbrella-shaped outer film and the top shell are arranged in a spaced mode. And the wrapping film is wrapped outside the bottom shell, the umbrella-shaped outer film and the top shell. The wrapping film is made of gastric soluble materials, under wrapping of the wrapping film, the large end of the umbrella-shaped outer film retracts, after the wrapping film is melted, the large end of the umbrella-shaped outer film is opened, and the inner diameter of the opened large end is larger than the outer diameter of the top shell. And the pull rope plays a traction role on the bottom shell. The stomach cells are collected by swallowing the capsule type cell collector, so that the discomfort degree of a physical examination person is reduced, the collection efficiency is improved, and meanwhile, the collection cost is also reduced.

Description

Technical Field

[0001] The present application belongs to the field of medical detection technology, and specifically relates to a diseased cell collector and a cold chain transport device thereof. Background Art

[0002] Cells are not only the components of human tissues, but also can be used to understand the health of the human body by analyzing cells. For example, by analyzing stomach cells, we can understand the health of the stomach.

[0003] Using cytological techniques to analyze cell morphology can detect whether there are abnormal cells, which is effective for early detection of cancer. Using modern molecular biology techniques, such as RNA sequencing, the gene expression pattern in gastric cells can be analyzed to discover biomarkers or gene expression changes associated with gastric disease. Through immunohistochemistry, specific protein expression in gastric cells can be detected to help diagnose diseases such as gastritis and gastric cancer. Analyzing the microbial DNA on gastric cells can understand the composition of the gastric microbial community and its relationship with gastric health. For example, the presence of Helicobacter pylori is associated with gastritis, gastric ulcers and gastric cancer. Detecting some biochemical markers secreted by gastric cells, such as gastrin and pepsinogen, can also reflect the functional state of the stomach.

[0004] However, the collection of gastric cells is currently mostly done by brushing or sucking cells from the surface of the gastric mucosa through a gastroscope. This causes great discomfort to the patients and may even require local or general anesthesia, which also increases the cost of cell collection. Summary of the invention

[0005] The technical problem to be solved by the present application is: to overcome the deficiencies of the prior art and to provide a diseased cell collector and a cold chain transport device thereof. The present application collects gastric cells by swallowing a capsule-type cell collector, thereby reducing the discomfort of the examinee, improving the collection efficiency, and also reducing the collection cost.

[0006] The technical solution adopted by this application to solve the problems existing in the prior art is:

[0007] A diseased cell collector comprises a bottom shell, an umbrella-shaped outer membrane, a top shell, a wrapping membrane and a drawstring.

[0008] The umbrella-shaped outer membrane is arranged between the bottom shell and the top shell, the small end of the umbrella-shaped outer membrane is fixedly connected to the bottom shell, and the large end of the umbrella-shaped outer membrane is arranged at a distance from the top shell.

[0009] The wrapping film is wrapped around the bottom shell, the umbrella-shaped outer film and the outside of the top shell.

[0010] The wrapping film is made of gastric soluble material. When wrapped by the wrapping film, the large end of the umbrella-shaped outer film shrinks. After the wrapping film melts, the large end of the umbrella-shaped outer film opens, and the inner diameter of the opened large end is larger than the outer diameter of the top shell.

[0011] The pull rope has a pulling effect on the bottom shell.

[0012] Preferably, the umbrella-shaped outer membrane is made of gastric-soluble material.

[0013] Preferably, the dissolution rate of the umbrella-shaped outer membrane is lower than the dissolution rate of the wrapping membrane.

[0014] Preferably, the bottom shell is internally supported by an elastic skeleton, the elastic skeleton comprises a plurality of elastic rods distributed in a circular array around the axis of the bottom shell, the front end of the elastic rod is provided with a bending area bent outward, the bending area is plugged with an inclined plug rod, and the plug rod is supported inside the umbrella-shaped outer membrane.

[0015] Preferably, the connecting rod is made of stomach-soluble material.

[0016] Preferably, the bottom shell and the top shell are made of soluble materials.

[0017] Preferably, the outer diameter of the open end of the bottom shell is smaller than the inner diameter of the open end of the top shell.

[0018] Preferably, the pull rope includes an inner pull rope and a tubular outer pull rope, the outer pull rope is sleeved outside the inner pull rope, the inner pull rope passes through the top shell and is fixedly connected to the bottom shell, and the outer pull rope is fixedly connected to the top shell.

[0019] A cold chain transport device comprises a test tube and a cold storage box, wherein a test tube placement device is arranged inside the cold storage box, a plurality of insertion holes are arranged on the test tube placement device, and the test tube is inserted into the insertion holes.

[0020] The open portion above the test tube is covered with a sealing cover, and the cell collector taken from the human body is placed inside the test tube.

[0021] Preferably, the cold storage box includes a box body and a box cover arranged above the box body, the test tube placement device is arranged inside the box body, and the test tube placement device includes a lower insulation board, and the jacks are arranged at intervals on the lower insulation board.

[0022] A plurality of chambers are arranged inside the lower insulation board, and refrigeration substances are arranged inside the chambers.

[0023] Compared with the prior art, the present invention has the following beneficial effects:

[0024] (1) Gastric cells are collected by swallowing a capsule-type cell collector, which reduces the discomfort of the examinee and improves the collection efficiency.

[0025] (2) The cell collector is directly placed into the test tube, and the bottom shell and the top shell are solvented by the solution inside the test tube. There is no need for the operator to take the sample out of the cell collector for a second time, thus avoiding secondary contamination.

[0026] (3) The refrigerator is opened with a random password to ensure that it will not be opened before it reaches the hands of the laboratory personnel, thus ensuring the safety of the samples. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The present application is further described below in conjunction with the accompanying drawings and embodiments.

[0028] Figure 1 This is a structural diagram of the initial state of a diseased cell collector for this application.

[0029] Figure 2 for Figure 1 An exploded diagram of

[0030] Figure 3 for Figure 1 A cross-sectional view of

[0031] Figure 4 for Figure 3 A partial enlarged view of the middle A.

[0032] Figure 5 for Figure 3 A partial enlarged view of point B in the middle.

[0033] Figure 6 This is a structural diagram of a diseased cell collector in this application, in which the wrapping film is melted and then unfolded.

[0034] Figure 7 for Figure 6 An exploded diagram of

[0035] Figure 8 for Figure 6 Internal skeleton structure diagram,

[0036] Fig. 9 for Figure 6 A cross-sectional view of

[0037] Fig.10 for Fig. 9 A top view of

[0038] Fig.11 for Fig.10 A partial enlarged view of point C in the middle.

[0039] Fig.12 for Fig.10 A partial enlarged view of point D in the middle.

[0040] Fig.13 This is a diagram of the retraction structure of a diseased cell collector when it is taken out in this application.

[0041] Fig.14 for Fig.13 An exploded diagram of

[0042] Fig.15 for Fig.13 A cross-sectional view of

[0043] Fig.16 This is the internal test tube structure diagram of the cold chain transport device for this application.

[0044] Fig.17 for Fig.16 Middle sealing cover structure diagram,

[0045] Fig.18 for Fig.16 A cross-sectional view of

[0046] Fig.19 for Fig.18 A partial enlarged view of point E in the middle.

[0047] Fig. 20 for Fig.16 An exploded diagram of

[0048] Fig.21 This is the structural diagram of the sealing cover in the free state of this application.

[0049] Fig. 22 This is a structural diagram of the refrigerated box in the sealed state in the cold chain transfer device of this application.

[0050] Fig.23 This is a structural diagram of the cold chain transfer device in this application when the refrigerated box is opened.

[0051] Fig.24 This is an exploded view of the test tube placement device in the cold storage box in the cold chain transport device of this application.

[0052] In the figure: 1001-elastic rod, 10011-bending area, 1002-plug rod, 10021-sleeve area, 1003-bottom shell, 1004-umbrella outer membrane, 1005-top shell, 1006-wrapping membrane, 1007-inner pull rope, 1008-outer pull rope;

[0053] 2001-test tube, 20011-sealing groove, 2002-sealing gasket, 2003-insertion body, 20031-transition zone, 2004-sealing body, 2005-support ring, 2006-notch, 2007-end ring, 2008-end, 2009-elastic member;

[0054] 3001-box body, 3002-box cover, 3003-lower insulation board, 30031-jack, 3004-chamber, 3005-cover plate, 3006-upper insulation board, 3007-anti-interference groove, 3008-lower lock body, 3009-upper lock body. DETAILED DESCRIPTION

[0055] For example, certain words are used in the specification and claims to refer to specific components. Those skilled in the art should understand that hardware manufacturers may use different terms to refer to the same component. This specification and claims do not use differences in names as a way to distinguish components, but use differences in the functions of components as the criteria for distinction. For example, "including" mentioned throughout the specification and claims is an open term, so it should be interpreted as "including but not limited to". "Approximately" means that within an acceptable error range, those skilled in the art can solve the technical problem within a certain error range and basically achieve the technical effect.

[0056] In the description of the present application, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "horizontal", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as limiting the present application.

[0057] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0058] The following is a further detailed description of a diseased cell collector and a cold chain transport device thereof of the present application in conjunction with the accompanying drawings, but it is not intended to limit the present application.

[0059] Embodiment 1:

[0060] A diseased cell collector, comprising Figures 1 to 5As shown, it includes a coaxially arranged bottom shell 1003, an umbrella-shaped outer film 1004, a top shell 1005, a wrapping film 1006, and a drawstring. The bottom shell 1003 is open at one end facing the top shell 1005, the top shell 1005 is open at one end facing the bottom shell 1003, and both ends of the umbrella-shaped outer film 1004 are open. The drawstring at least plays a pulling role on the bottom shell 1003.

[0061] The umbrella-shaped outer membrane 1004 is arranged between the bottom shell 1003 and the top shell 1005 , the small end of the umbrella-shaped outer membrane 1004 is fixedly connected to the bottom shell 1003 , and the large end of the umbrella-shaped outer membrane 1004 is spaced apart from the top shell 1005 .

[0062] Depend on Figure 4 as well as Figure 5 As shown, the wrapping film 1006 is wrapped around the bottom shell 1003 , the umbrella-shaped outer film 1004 and the outside of the top shell 1005 , and the bottom shell 1003 and the top shell 1005 are fixedly connected by the wrapping film 1006 .

[0063] The wrapping film 1006 is made of gastric soluble material, and the umbrella-shaped outer membrane 1004 is elastic. Under the wrapping and squeezing of the wrapping film 1006, the large end of the umbrella-shaped outer membrane 1004 shrinks, presenting Figure 2 After the wrapping film 1006 melts, the umbrella-shaped outer membrane 1004 opens at the large end, presenting Figure 6 Status. Fig. 9 as well as Fig.10 As shown, the inner diameter of the expanded large end is larger than the outer diameter of the top shell 1005 .

[0064] When used, by Figure 1 In the initial installation of the cell collector shown in the figure, the examinee takes the cell collector orally, and the end of the drawstring is left outside the mouth. The position where the cell collector enters the human body can be controlled by the length of the drawstring, and its predetermined destination is the stomach. When the cell collector enters the stomach, under the action of gastric juice, the wrapping film 1006 dissolves, releasing the pressure on the umbrella-shaped outer membrane 1004, and the umbrella-shaped outer membrane 1004 opens, and the entire cell collector appears Figure 6 In the state shown, the outer diameter of the large end of the umbrella-shaped outer membrane 1004 is larger than the outer diameter of the top shell 1005.

[0065] Then, the cell collector is lifted up by pulling the drawstring. During the upward movement of the cell collector, the umbrella-shaped outer membrane 1004 scrapes the stomach wall and the esophageal wall to collect cells shed from the surface of the stomach wall and the esophageal wall. The cells and a small amount of gastric juice are temporarily stored inside the bottom shell 1003.

[0066] Without scraping the stomach wall and esophageal wall, there is a certain amount of cell tissue shed from the stomach wall and esophageal wall in the gastric juice, and the cell tissue can also be collected.

[0067] The top shell 1005 can also be made of a stomach-soluble material, which dissolves together with the wrapping film 1006 in the stomach to expand the sampling diameter of the umbrella-shaped outer membrane 1004.

[0068] Embodiment 2:

[0069] This embodiment is based on the above-mentioned embodiment 1, but the difference is that in order to improve the support strength of the bottom shell 1003 and the opening strength of the umbrella-shaped outer membrane 1004, the bottom shell 1003 is supported by an elastic skeleton. Figure 8 As shown, the elastic skeleton comprises a plurality of elastic rods 1001 distributed in a circular array around the axis of the bottom shell 1003, the front end of the elastic rod 1001 is provided with a bending area 10011 bent outward, and an inclined plug-in rod 1002 is plugged into the bending area 10011. The plug-in rod 1002 comprises a solid area and a sleeve area 10021, and the sleeve area 10021 is sleeved on the bending area 10011. The plug-in rod 1002 is supported inside the umbrella-shaped outer membrane 1004.

[0070] The elastic skeleton is provided to increase the support strength of the bottom shell 1003, thereby preventing the bottom shell 1003 from deforming inside the human body and causing the collected cells to fall out. At the same time, the elastic rod 1001 is elastic. When the wrapping film 1006 is wrapped, the plug rod 1002 is squeezed, which in turn increases the bending angle of the bending zone 10011, which is equivalent to storing elastic kinetic energy. When the wrapping film 1006 is dissolved, the plug rod 1002 is released from the squeeze, and the elastic kinetic energy of the bending zone 10011 is released, and its bending angle decreases, swinging outward, and the umbrella-shaped outer membrane 1004 is unfolded, presenting a Figure 6 Status shown.

[0071] Embodiment 3:

[0072] This embodiment is based on the above-mentioned embodiment 2, except that the structure of the pull rope and the materials used to make the plug rod 1002, the umbrella-shaped outer membrane 1004 and the top shell 1005 are changed to improve the patient's comfort when the cell collector is removed.

[0073] The plug rod 1002 and the umbrella-shaped outer membrane 1004 are made of gastric soluble materials, and the dissolution rate of the plug rod 1002 and the umbrella-shaped outer membrane 1004 is lower than the dissolution rate of the wrapping film 1006. The dissolution rate between the two can be adjusted in a variety of ways:

[0074] First, the thickness of the wrapping film 1006 is smaller than the thickness of the umbrella-shaped outer film 1004 and the plug-in rod 1002, and the dissolution rate is changed by the difference in thickness;

[0075] The second type is that the wrapping film 1006, the umbrella-shaped outer film 1004 and the plug-in rod 1002 are made of different materials, for example, the wrapping film 1006 is made of type B gelatin, while the umbrella-shaped outer film 1004 and the plug-in rod 1002 are made of type A gelatin;

[0076] The third method is to add a water-soluble or fast-soluble coating, such as a sugar coating or other water-soluble polymers, to the outside of the packaging film 1006 to accelerate the dissolution rate of the packaging film 1006 .

[0077] The dissolution rates of the wrapping film 1006 and the umbrella-shaped outer membrane 1004 are changed by any of the above methods, that is, after the wrapping film 1006 is dissolved, the umbrella-shaped outer membrane 1004 is dissolved after one end is opened, so as to prolong the time of cell sampling.

[0078] At the end of sampling, the umbrella-shaped outer membrane 1004 and the plug-in rod 1002 are also dissolved, and only the elastic rod 1001, the bottom shell 1003, the top shell 1005 and the pull rope remain in the entire cell collector. The pull rope includes an inner pull rope 1007 and a tubular outer pull rope 1008, the outer pull rope 1008 is sleeved outside the inner pull rope 1007, the inner pull rope 1007 passes through the top shell 1005 and is fixedly connected to the bottom shell 1003, and the outer pull rope 1008 is fixedly connected to the top shell 1005.

[0079] Depend on Figures 13 to 15 As shown, by pulling up the inner drawstring 1007, the bottom shell 1003 and the elastic frame are moved toward the top shell 1005. Since the outer diameter of the open end of the bottom shell 1003 is smaller than the inner diameter of the open end of the top shell 1005, the bottom shell 1003 can enter the top shell 1005. The top shell 1005 seals the bottom shell 1003 to ensure that the sample inside the bottom shell 1003 will not leak when the cell collector is taken out of the human body.

[0080] After the bottom shell 1003 is in place, the inner pull rope 1007 and the outer pull rope 1008 are pulled simultaneously to pull the remaining cell collector out of the human body through the mouth.

[0081] In the above three embodiments, the gastric soluble material can be gelatin, which is a prior art.

[0082] After taking out the cell collector, the sample inside needs to be placed in a test tube containing a solution to preserve the sample, and then transported through cold chain transportation to a designated testing agency for analysis and testing to determine the health of the human body. In the current working mode, the cell collector needs to be opened and the sample inside needs to be poured into the test tube. In this process, the sample is easily contaminated.

[0083] To solve the above problems, the present application provides a cold chain transport device, including a test tube 2001 and a cold storage box. The cold storage box is provided with a test tube placement device, the test tube placement device is provided with a plurality of plug holes 30031, and the test tube 2001 is inserted into the plug holes 30031.

[0084] Depend on Figures 16 to 21 As shown, a sealing cover is provided on the open top of the test tube 2001 , and a cell collector taken from a human body is placed inside the test tube 2001 .

[0085] The pH value of the solution filled in the test tube 2001 is greater than 7. The bottom shell 1003 and the top shell 1005 are made of soluble materials, which can be dissolved in the solution with a pH value greater than 7, lose the storage effect on the sample, and the sample is mixed into the solution in the test tube 2001. For example, the solution filled in the test tube 2001 is Tris buffer or Hanks' Balanced Salt Solution (HBSS) solution.

[0086] The typical pH range of Tris (tris(hydroxymethyl)aminomethane) buffer is usually between 7.0 and 9.2, which is the most effective pH range for Tris as a buffer at room temperature (about 25°C). Tris buffer is widely used in biochemistry and molecular biology experiments due to its excellent buffering properties under neutral to weakly alkaline conditions.

[0087] The pH of Hanks' Balanced Salt Solution (HBSS) is usually set within a physiologically relevant range to support short-term culture or treatment of cells. The pH of HBSS may vary slightly depending on the supplier and specific formulation, but is usually maintained between 7.2 and 7.4. This range is set based on the optimal pH of cell physiology to ensure that cells can remain viable when treated with HBSS.

[0088] The bottom shell 1003 and the top shell 1005 can be made of enteric material and can be dissolved in a solution with a pH greater than 7.

[0089] In this way, the sealing cover on the test tube 2001 is opened, and the taken-out cell collector is directly placed into the test tube. The operator does not need to touch the cell collector, thereby avoiding secondary contamination of the sample.

[0090] In this embodiment, a sealing groove 20011 is concavely provided on the top surface of the test tube 2001, and a sealing gasket 2002 is provided inside the sealing groove 20011. The provision of the sealing gasket 2002 optimizes the sealing effect after the sealing cover is tightly closed.

[0091] The sealing cover comprises an inserting body 2003 and a sealing body 2004 which are integrally formed. The outer diameter of the sealing body 2004 is larger than the outer diameter of the inserting body 2003 . The inserting body 2003 is inserted into the interior of the test tube 2001 to seal the test tube 2001 .

[0092] Furthermore, the inserting body 2003 and the sealing body 2004 are made of elastic rubber material, and a notch 2006 is provided on the circumferential surface of the inserting body 2003 and the sealing body 2004 , and the drawstring of the cell collector is clamped inside the notch 2006 .

[0093] A plurality of support rings 2005 with through holes are fixed on the circumferential surface of the sealing body 2004, and an end ring 2007 with through holes is respectively provided at both ends of the notch 2006. An end head 2008 is clamped inside the end ring 2007, and an elastic member 2009 is fixedly connected to one end of the two end heads 2008 away from the notch 2006, and the elastic member 2009 passes through the through hole of the support ring 2005. In this embodiment, the elastic member 2009 is an elastic rope.

[0094] When the sealing cap is removed from the test tube 2001, Fig.21 As shown, under the pull of the elastic member 2009, the slot 2006 is in an open state, the drawstring can be clamped inside the slot 2006, the cell collector is placed inside the test tube 2001, and then the insert 2003 is inserted into the test tube 2001. In order to facilitate insertion, the bottom of the insert 2003 is provided with a transition area 20031 with a circular arc or chamfer.

[0095] When the insert 2003 is inserted, the notch 2006 retracts under the squeezing effect of the test tube 2001, and finally the notch 2006 is formed by Fig.17 The closed state shown in the figure completes the sealing and the clamping of the drawstring. The operator only needs to cut the drawstring outside the sealing body 2004.

[0096] Depend on Figure 22 to Figure 24 As shown, the refrigerator comprises a box body 3001 and a box cover 3002 arranged above the box body 3001 , one end of the two are hinged, and the other end is locked by a lower lock body 3008 and an upper lock body 3009 .

[0097] The test tube placement device is arranged inside the box 3001, and the test tube placement device includes a lower insulation plate 3003 and an upper insulation plate 3006 which are arranged separately, and the jacks 30031 are arranged on the lower insulation plate 3003 at intervals.

[0098] The lower insulation board 3003 is provided with a plurality of chambers 3004, and the chambers 3004 are provided with refrigerants. In order to reduce costs, the refrigerants are replaceable. In order to facilitate the taking and placing of the refrigerants, the upper end of the chamber 3004 is open, and a detachable cover 3005 is provided at the open end. The refrigerants can be bagged ice bags, dry ice or phase change energy storage capsules.

[0099] The lower insulation plate 3003 is detachably or fixedly connected to the box body 3001, and the upper insulation plate 3006 is detachably or fixedly connected to the box cover 3002. An anti-interference groove 3007 is provided at the bottom of the upper insulation plate 3006, so that when the box cover 3002 is closed, there will be no interference with the test tube 2001 and the sealing cover.

[0100] In this embodiment, the lower lock body 3008 and the upper lock body 3009 used in conjunction with each other can be password locks, which have a remote transmission module and can be controlled by a mobile phone APP to generate a random password. When the refrigerated box is transported to the hands of the laboratory personnel, the laboratory personnel contact the sampling or sealing personnel, and the sampling or sealing personnel send the random password to the laboratory personnel, who then open the lock body using the random password.

[0101] Through the above settings, it can be ensured that the refrigerator will not be opened before it reaches the hands of the laboratory personnel, ensuring the safety of the samples.

[0102] The implementation methods of the present application are described in detail above in conjunction with the accompanying drawings, but the present application is not limited to the above implementation methods, and various changes can be made within the knowledge scope of ordinary technicians in the relevant technical field without departing from the purpose of the present application.

Claims

1. A diseased cell collector, characterized in that: It includes a bottom shell (1003), an umbrella-shaped outer membrane (1004), a top shell (1005), a wrapping membrane (1006) and a drawstring; The umbrella-shaped outer membrane (1004) is arranged between the bottom shell (1003) and the top shell (1005), the small end of the umbrella-shaped outer membrane (1004) is fixedly connected to the bottom shell (1003), and the large end of the umbrella-shaped outer membrane (1004) is arranged at intervals with the top shell (1005); The wrapping film (1006) is wrapped around the outside of the bottom shell (1003), the umbrella-shaped outer film (1004) and the top shell (1005); The wrapping film (1006) is made of a gastric-soluble material. When wrapped by the wrapping film (1006), the large end of the umbrella-shaped outer film (1004) retracts. After the wrapping film (1006) melts, the large end of the umbrella-shaped outer film (1004) opens, and the inner diameter of the opened large end is greater than the outer diameter of the top shell (1005). The pull rope has a pulling effect on the bottom shell (1003).

2. A diseased cell collector according to claim 1, characterized in that: The umbrella-shaped outer membrane (1004) is made of gastric-soluble material.

3. A diseased cell collector according to claim 2, characterized in that: The dissolution rate of the umbrella-shaped outer film (1004) is lower than the dissolution rate of the wrapping film (1006).

4. A diseased cell collector according to claim 2 or 3, characterized in that: The bottom shell (1003) is supported internally by an elastic skeleton, and the elastic skeleton comprises a plurality of elastic rods (1001) distributed in a ring array around the axis of the bottom shell (1003). The front end of the elastic rod (1001) is provided with a bending area (10011) bent outward, and an inclined plug-in rod (1002) is plugged into the bending area (10011), and the plug-in rod (1002) is supported inside the umbrella-shaped outer membrane (1004).

5. The diseased cell collector according to claim 4, characterized in that: The plug rod (1002) is made of stomach-soluble material.

6. The diseased cell collector according to claim 5, characterized in that: The bottom shell (1003) and the top shell (1005) are made of soluble materials.

7. A diseased cell collector according to claim 5 or 6, characterized in that: The outer diameter of the open end of the bottom shell (1003) is smaller than the inner diameter of the open end of the top shell (1005).

8. The diseased cell collector according to claim 7, characterized in that: The pull rope includes an inner pull rope (1007) and a tubular outer pull rope (1008), wherein the outer pull rope (1008) is sleeved on the outside of the inner pull rope (1007), the inner pull rope (1007) passes through the top shell (1005) and is fixedly connected to the bottom shell (1003), and the outer pull rope (1008) is fixedly connected to the top shell (1005).

9. A cold chain transport device, characterized in that: It comprises a test tube (2001) and a cold storage box, wherein a test tube placement device is provided inside the cold storage box, and the test tube placement device is provided with a plurality of plug holes (30031), and the test tube (2001) is inserted inside the plug holes (30031); The open portion above the test tube (2001) is covered with a sealing cover, and a cell collector taken from a human body is placed inside the test tube (2001).

10. A cold chain transport device according to claim 9, characterized in that: The cold storage box comprises a box body (3001) and a box cover (3002) arranged above the box body, the test tube placement device is arranged inside the box body (3001), the test tube placement device comprises a lower insulation board (3003), and the jacks (30031) are arranged at intervals on the lower insulation board (3003); The lower insulation plate (3003) is provided with a plurality of chambers (3004) inside, and the chambers (3004) are provided with refrigeration material inside.

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