A multi-chamber mixed extrusion tank and toothpaste thereof

Through the design of the multi-storey hybrid extrusion tank body, the quantitative extrusion of toothpaste is achieved by using the combination of airbags and pistons, and the problems of complex structure and inconsistent paste output are solved, providing flexible usage methods and low-cost solutions.

CN119349002BActive Publication Date: 2025-04-15SUZHOU FRESH HEALTH TECH CO LTD
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Patent Information

Application Number
CN202411919417.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-12-25
Publication Date
2025-04-15
Estimated Expiration
2044-12-25

AI Technical Summary

Technical Problem

The existing toothpaste paste tube has complex structure and high cost, is prone to clogging, and cannot achieve consistency in the amount of paste produced at each press, resulting in inconvenience in use.

Method used

The multi-storey hybrid extrusion tank is used to inflate the airbag by pressing the rubber ball, and the airbag expands and pushes the piston upward, realizing quantitative extrusion of the paste. The design does not require a pump head, is simple in structure, is low in cost, and can adjust the proportion of toothpaste ingredients according to needs.

Benefits of technology

The consistency of the amount of paste produced per press is achieved, and it is flexible to use, which is convenient to adjust the proportion of toothpaste ingredients according to different needs, reducing the inconvenience of use.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention provides a multi-chamber mixed extrusion tank body and toothpaste thereof, the toothpaste tube comprising a tube body assembly and a tube head assembly connected to the tube body assembly; the tube body assembly is formed by splicing at least two tube body units, each tube body unit has a tube cavity, the inner sides of the plurality of tube body units form an installation channel, an air supply pipe is arranged in the installation channel, a piston push plate and an air bag assembly are arranged in the tube cavity of each tube body unit, and the air supply pipe is connected to the air bag assembly; the tube head assembly comprises a tube head body, a paste outlet nozzle arranged on the tube head body, the paste outlet nozzles are respectively connected to the tube cavities of the tube body units, a rubber pressing ball is arranged in the tube head body, an air inlet hole is arranged on the rubber pressing ball, a second one-way valve is arranged in the air inlet hole, the air outlet of the rubber pressing ball is connected to an air outlet pipe, the air outlet pipe is connected to all the air supply pipes through a regulating valve, and an operating key for controlling the regulating valve to change the gas flow ratio between the air supply pipes is also arranged on the tube head body.
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Description

Technical Field

[0001] The present application relates to the field of toothpaste, and in particular to a multi-chamber mixing extrusion tank and toothpaste thereof. Background Art

[0002] There are many kinds of toothpaste in the prior art, including whitening type and gum protection type in terms of their functions. In addition, there is children's toothpaste for children. As a necessity in daily life, each family will choose the corresponding toothpaste according to the characteristics of the teeth of each family member, and then multiple tubes of toothpaste are needed. As consumers pay more attention to the oral cavity, they will even adjust the use of different types of toothpaste according to the condition of the teeth at different stages, which brings many inconveniences.

[0003] In addition, current toothpaste is usually a manually squeezed tube type. When using it, different users squeeze it according to their own usage needs. However, the remaining amount of toothpaste is different and the temperature difference between seasons is different. Not everyone can achieve accurate quantification. That is, there is more or less difference in the amount squeezed each time. Although it does not affect normal use, it is impossible to achieve scientific management of the oral system.

[0004] Although there are pump-type toothpastes on the market, they are not popular at present. The fundamental reasons include: first, the pump head structure is complex and costly, and unlike cosmetics, it is easy for toothpaste to get clogged; second, as the toothpaste is used, the amount of toothpaste in the inner cavity varies, causing the amount of toothpaste discharged each time it is pressed to change, making it inconvenient to use.

[0005] In view of this, those skilled in the art need to improve the current toothpaste tube structure to overcome the above-mentioned defects. Summary of the invention

[0006] The main purpose of the present application is to provide a multi-chamber mixing extrusion tank and toothpaste thereof, which can achieve a consistent amount of paste each time it is pressed, does not require a pump head, has a simple structure and low cost, and can also be used in combination with whitening type and gum protection type, and can adjust the ratio of the two components according to user needs, making it flexible and convenient to use.

[0007] In order to achieve the above-mentioned purpose, in a first aspect, the present application provides a multi-chamber mixed extrusion tank body, comprising a tube body assembly and a tube head assembly connected to the tube body assembly;

[0008] The tube body assembly is formed by splicing at least two tube body units, each of which has a tube cavity, and a mounting channel is formed on the inner side of the plurality of tube body units, and an air supply pipe corresponding to the tube body unit is arranged in the mounting channel, and a piston push plate and an airbag assembly are arranged in the tube cavity of each tube body unit, and the airbag assembly is located below the piston push plate, and the air supply pipe is connected to the airbag assembly in the corresponding tube body unit through a first one-way valve;

[0009] The tube head assembly includes a tube head body, a paste outlet nozzle arranged on the tube head body, the paste outlet nozzles are respectively connected with the tube cavities of the tube body unit, a rubber pressing ball is arranged in the tube head body, an air inlet is arranged on the rubber pressing ball, a second one-way valve is arranged in the air inlet, an air outlet of the rubber pressing ball is connected with an air outlet pipeline, the air outlet pipeline is connected with all the air supply pipes through a regulating valve, and an operation key for controlling the regulating valve to change the gas flow ratio between the air supply pipes is also arranged on the tube head body;

[0010] A pressing piece is also slidably arranged on the tube head assembly, and the top of the rubber pressing ball is in conflict with the pressing piece.

[0011] Optionally, there are two tube body units, and toothpaste paste A and toothpaste paste B are respectively arranged in the tube cavities of the two tube body units, and the regulating valve is a three-way regulating valve.

[0012] Optionally, the operation key is a knob that is rotatably arranged on the tube head body, and the knob is surrounded by ratio scales of toothpaste paste A and toothpaste paste B.

[0013] Optionally, the tube head body is threadedly connected to the upper part of the tube body unit, the paste outlet nozzle is connected to the tube cavity of the tube body unit through a connecting hose, and the connecting hose is plugged into and matched with the paste outlet of the tube body unit.

[0014] Optionally, the airbag assembly is in a continuously bent shape.

[0015] Optionally, the airbag assembly includes a plurality of airbag units connected in sequence.

[0016] Optionally, the pressing member is a hollow structure.

[0017] Optionally, a tube cover matched with the tube body assembly is further included, and the tube cover is arranged above the tube head assembly.

[0018] In order to achieve the above-mentioned purpose, in a second aspect, the present application provides a multi-chamber mixed extrusion toothpaste, comprising a tube body assembly and a tube head assembly connected to the tube body assembly;

[0019] The tube body assembly is formed by splicing two tube body units, each of which has a tube cavity, and a mounting channel is formed on the inner side of the plurality of tube body units, and an air supply pipe corresponding to the tube body unit is arranged in the mounting channel, and a piston push plate and an airbag assembly are arranged in the tube cavity of each tube body unit, and the airbag assembly is located below the piston push plate, and the air supply pipe is connected to the airbag assembly in the corresponding tube body unit through a first one-way valve;

[0020] The tube head assembly includes a tube head body, a paste outlet nozzle arranged on the tube head body, the paste outlet nozzles are respectively connected with the tube cavities of the tube body unit, a rubber pressing ball is arranged in the tube head body, an air inlet is arranged on the rubber pressing ball, a second one-way valve is arranged in the air inlet, an air outlet of the rubber pressing ball is connected with an air outlet pipeline, the air outlet pipeline is connected with all the air supply pipes through a regulating valve, and an operation key for controlling the regulating valve to change the gas flow ratio between the air supply pipes is also arranged on the tube head body;

[0021] A pressing piece is also slidably provided on the tube head assembly, and the top of the rubber pressing ball is in conflict with the pressing piece;

[0022] The two tube units are respectively loaded with a freshening composition toothpaste and a natural gum protection composition toothpaste;

[0023] The refreshing toothpaste composition comprises, by weight, 0.2-2 parts of persimmon fruit extract or emblica extract or shiitake mushroom extract, 0.01-0.5 parts of plant enzyme, 0.01-0.5 parts of complex amino acid, 0.5-3 parts of PVM / MA copolymer, 10-25 parts of abrasive, 5-66 parts of moisturizing agent, 0.1-2 parts of thickener, 0.1-5 parts of sweetener, 1-3 parts of foaming agent, appropriate amount of pH regulator and 0.1-2 parts of stabilizer, 0.5-1.5 parts of fragrance, and the rest is water;

[0024] The natural gum protection composition toothpaste comprises, by weight, 0.5-5 parts of gum protection composition, 10-30 parts of abrasive, 20-66 parts of moisturizer, 0.1-2 parts of thickener, 0.1-5 parts of sweetener, 1-3 parts of foaming agent, an appropriate amount of pH regulator and 0.1-2 parts of stabilizer, 0.5-1.5 parts of fragrance, and the rest is water.

[0025] Optionally, the gum protection composition is at least one of scutellaria baicalensis, magnolia bark extract, chamomile derivatives, dipotassium glycyrrhizinate, and perilla seed extract.

[0026] The multi-chamber mixed extrusion tank body and toothpaste thereof provided by the present invention have the beneficial effect, compared with the prior art, that air is inflated into the airbag by pressing the rubber pressing ball, and the airbag pushes the piston push plate to rise after expansion, so as to extrude the paste. Since the volume of the rubber pressing ball is consistent, that is, the inflation amount of each deformation is consistent, thus achieving a consistent amount of paste output each time pressing. In addition, toothpaste pastes with two functions coexist in the same toothpaste and can be adjusted by a regulating valve, that is, the ratio of the two components can be set according to needs, which is flexible and convenient to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The drawings constituting a part of this application are used to provide a further understanding of this application, so that other features, purposes and advantages of this application become more obvious. The schematic embodiment drawings and their descriptions of this application are used to explain this application and do not constitute an improper limitation on this application. In the drawings:

[0028] Figure 1 This invention illustrates Figure 1 ;

[0029] Figure 2 This invention illustrates Figure 2 ;

[0030] Figure 3 is a schematic diagram of a tube unit;

[0031] Figure 4 It's an airbag indicator Figure 1 ;

[0032] Figure 5 It's an airbag indicator Figure 2 ;

[0033] Figure 6 It is the experimental result - Fusobacterium nucleatum (Fn) antibacterial experiment;

[0034] Figure 7 It is the experimental result - Clostridium morelense (Sm) inhibition experiment;

[0035] Figure 8 This is the experimental result - Porphyromonas gingivalis (Pg) antibacterial experiment.

[0036] Among them: 1. Tube unit, 2. Tube cavity, 3. Piston push plate, 4. Airbag assembly, 5. Installation channel, 6. Air supply pipe, 7. Tube head body; 8. Tube cover; 9. Paste outlet nozzle; 10. Rubber pressing ball; 11. Pressing part; 12. Regulating valve; 13. First one-way valve; 14. Operation key. DETAILED DESCRIPTION

[0037] In order to enable those skilled in the art to better understand the solution of the present application, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present application.

[0038] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequential order. It should be understood that the data used in this way can be interchanged where appropriate, so that the embodiments of the present application described here. In addition, the terms "including" and "having" and any of their variations are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device comprising a series of steps or units is not necessarily limited to those steps or units clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0039] In the present application, the terms "upper", "lower", "left", "right", "front", "back", "top", "bottom", "inner", "outer", "middle", "vertical", "horizontal", "lateral", "longitudinal" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings. These terms are mainly used to better describe the present application and its embodiments, and are not used to limit the indicated devices, elements or components to have a specific orientation, or to be constructed and operated in a specific orientation.

[0040] In addition, some of the above terms may be used to express other meanings in addition to indicating orientation or positional relationship. For example, the term "on" may also be used to express a certain dependency or connection relationship in some cases. For those of ordinary skill in the art, the specific meanings of these terms in this application can be understood according to specific circumstances.

[0041] In addition, the term "plurality" shall mean two or more.

[0042] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present application will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0043] like Figure 1-Figure 5 As shown, a multi-chamber mixed extrusion tank body includes a tube body assembly and a tube head assembly connected to the tube body assembly;

[0044] The tube body assembly is formed by splicing at least two tube body units 1, each of which has a tube cavity 2, and a mounting channel 5 is formed on the inner side of the plurality of tube body units 1, and an air supply pipe 6 corresponding to the tube body units 1 is arranged in the mounting channel 5, and a piston push plate 3 and an airbag assembly 4 are arranged in the tube cavity 2 of each tube body unit 1, and the airbag assembly 4 is located below the piston push plate 3, and the air supply pipe 6 is connected to the airbag assembly 4 in the corresponding tube body unit 1 through a first one-way valve 13;

[0045] The tube head assembly includes a tube head body 7, a paste outlet nozzle 9 arranged on the tube head body 7, the paste outlet nozzles 9 are respectively connected to the tube cavity 2 of the tube body unit 1, a rubber pressing ball 10 is arranged in the tube head body 7, an air inlet hole is arranged on the rubber pressing ball 10, a second one-way valve is arranged in the air inlet hole, the air outlet of the rubber pressing ball 10 is connected to an air outlet pipeline, and the air outlet pipeline is connected to all the air supply pipes 6 through a regulating valve 12, and the tube head body 7 is also provided with an operation key 14 for controlling the regulating valve 12 to change the gas flow ratio between the air supply pipes 6;

[0046] A pressing piece 11 is also slidably disposed on the tube head assembly, and the top of the rubber pressing ball 10 is in conflict with the pressing piece 11 .

[0047] The principle is that the volume of the rubber pressing ball 10 does not change. Therefore, each time it is pressed, the stroke of the operating pressing member 11 is consistent, so that when the rubber pressing ball 10 is compressed, the amount of gas filled into the air supply pipe 6 is constant, and then the rubber pressing ball 10 recovers itself by elasticity and at the same time, the external gas is sucked into the rubber pressing ball 10 through the first one-way valve 13. At the same time, the recovery of the rubber pressing ball 10 causes the pressing member 11 to reset itself, so that the amount of gas filled into the airbag is constant each time. Since the tube unit 1 is a columnar structure with a consistent cross-sectional size, the moving distance of the piston push plate 3 is consistent, and finally the amount of paste output is constant, so that each time the toothpaste can be quantitatively squeezed out. Finally, since multiple tube units 1 are provided, each tube unit 1 is loaded with toothpastes with different functions, and the regulating valve 12 is operated by operating the operating key 14, thereby achieving It is found that each time the air is inflated, the amount of gas entering different air supply pipes 6 can be adjusted. The air supply pipe 6 with a larger amount of inflation has a larger amount of change in the corresponding air bag, so that the piston push plate 3 rises a larger amount, and thus the amount of paste discharged is larger. Therefore, when using it, consumers can use it flexibly according to the condition of their own teeth. For example, a user who needs long-term teeth whitening can increase the amount of gum protection toothpaste used each time when the gum condition occurs, and then increase the amount of whitening toothpaste used after the gum condition improves. In order to facilitate the user's reference operation, the operation key 14 is a knob that is rotated on the tube head body 7, and the knob is surrounded by a ratio scale of toothpaste paste A and toothpaste paste B. The user only needs to adjust the ratio to be set, and each press can achieve quantitative discharge of the two toothpastes according to the set ratio.

[0048] It should be noted that the above-mentioned can body is not limited to use in toothpaste, but can also be used for packaging of viscous oral care essence, skin care products and other products.

[0049] In this embodiment, there are two tube body units 1 , and toothpaste A and toothpaste B are respectively arranged in the tube cavities 2 of the two tube body units 1 , and the regulating valve 12 is a three-way regulating valve 12 .

[0050] Of course, in addition to this, the tube body unit 1 can also be set to three, that is, whitening toothpaste, gum protection toothpaste and children's toothpaste are respectively set in the tube body unit 1, so that the same toothpaste can meet the needs of a family of three at the same time, and there is no need to purchase multiple types of toothpastes additionally. It can not only manage the oral cavity scientifically but also save living costs.

[0051] Optionally, the tube head body 7 is threadedly connected to the upper part of the tube body unit 1, the paste outlet nozzle 9 is connected to the tube cavity 2 of the tube body unit 1 through a connecting hose, and the connecting hose is plugged into the paste outlet of the tube body unit 1.

[0052] In order to make the airbag sufficient to squeeze out the toothpaste in the lumen 2 completely and avoid waste, the deformation of the airbag needs to be large enough, so the airbag component 4 needs to be optimized, such as Figure 3 As shown, the airbag assembly 4 is in a continuously bent shape. In addition, the airbag assembly 4 can also be in a continuously bent shape. Figure 4 The airbag assembly 4 shown includes a plurality of airbag units connected in sequence.

[0053] In order to enable the rubber pressing ball 10 to communicate with the outside world for inflation, the pressing member 11 is a hollow structure.

[0054] In order to keep the paste dispensing nozzle 9 clean and hygienic, a tube cover 8 matched with the tube body assembly is also included, and the tube cover 8 is arranged above the tube head assembly.

[0055] It should be noted that when this product is purchased and used, it needs to be pressed multiple times for the first time so that each tube unit 1 can discharge the paste. Since the connecting channel between the tube cavity 2 and the paste discharge nozzle 9 is a hollow structure when leaving the factory, it is necessary to press multiple times to fill the connecting channel with the paste before the quantitative and top ratio pressing and discharging of the paste can be achieved.

[0056] In addition, this embodiment also provides a multi-chamber mixed extrusion toothpaste, including a tube body assembly and a tube head assembly connected to the tube body assembly;

[0057] The tube body assembly is formed by splicing two tube body units 1, each of which has a tube cavity 2, and a mounting channel 5 is formed on the inner side of the plurality of tube body units 1, and an air supply pipe 6 corresponding to the tube body units 1 is arranged in the mounting channel 5, and a piston push plate 3 and an airbag assembly 4 are arranged in the tube cavity 2 of each tube body unit 1, and the airbag assembly 4 is located below the piston push plate 3, and the air supply pipe 6 is connected to the airbag assembly 4 in the corresponding tube body unit 1 through a first one-way valve 13;

[0058] The tube head assembly includes a tube head body 7, a paste outlet nozzle 9 arranged on the tube head body 7, the paste outlet nozzles 9 are respectively connected to the tube cavity 2 of the tube body unit 1, a rubber pressing ball 10 is arranged in the tube head body 7, an air inlet hole is arranged on the rubber pressing ball 10, a second one-way valve is arranged in the air inlet hole, the air outlet of the rubber pressing ball 10 is connected to an air outlet pipeline, and the air outlet pipeline is connected to all the air supply pipes 6 through a regulating valve 12, and the tube head body 7 is also provided with an operation key 14 for controlling the regulating valve 12 to change the gas flow ratio between the air supply pipes 6;

[0059] A pressing piece 11 is also slidably provided on the tube head assembly, and the top of the rubber pressing ball 10 is in conflict with the pressing piece 11;

[0060] The two tube units 1 are respectively loaded with a freshening composition toothpaste and a natural gum protection composition toothpaste;

[0061] The refreshing toothpaste composition includes 0.2-2 parts of persimmon fruit extract or emblica extract or shimeji extract, 0.01-0.5 parts of plant enzyme, 0.01-0.5 parts of complex amino acid, 0.5-3 parts of PVM / MA copolymer, 10-25 parts of abrasive, 5-66 parts of moisturizer, 0.1-2 parts of thickener, 0.1-5 parts of sweetener, 1-3 parts of foaming agent, appropriate amount of pH regulator and 0.1-2 parts of stabilizer, 0.5-1.5 parts of fragrance, and the rest is water, wherein persimmon fruit comes from green immature fruit, which is obtained after multiple processes to remove astringency, and is rich in tannins, polyphenols, amino acids, etc. Plant enzymes are natural enzyme preparations. PVM / MA, with a high molecular weight network structure, is a very effective alkaline phosphatase inhibitor, and provides sustained release and long-lasting effects through film formation; the complex amino acid contains arginine, glycine, lysine, and histidine.

[0062] The natural gum protection composition toothpaste comprises, by weight, 0.5-5 parts of gum protection composition, 10-30 parts of abrasive, 20-66 parts of moisturizer, 0.1-2 parts of thickener, 0.1-5 parts of sweetener, 1-3 parts of foaming agent, an appropriate amount of pH regulator and 0.1-2 parts of stabilizer, 0.5-1.5 parts of fragrance, and the rest is water. Preferably, the gum protection composition is at least one of scutellaria baicalensis, magnolia bark extract, chamomile derivative, dipotassium glycyrrhizate, and perilla seed extract, wherein scutellaria baicalensis is derived from the bark or root bark of the ilex plant of the ilex family, which is crushed, ultrasonically extracted, and dried; dipotassium glycyrrhizate and perilla seed extract are both derived from natural plants, and their combined use has significant effects of inhibiting dental plaque, alleviating gingivitis, and promoting the healing of recurrent oral ulcers. The total effective content of Magnolia officinalis extract is more than 98%, and the mass ratio of magnolol to honokiol is 1:1. The test on the dental caries pathogen, namely Streptococcus mutans, shows that it has a high-efficiency and rapid bactericidal effect. Chamomile derivatives are extracted from a plant of chamomile to obtain a derivative of azulene, guaiazulene, on which a sodium sulfonate group is connected to the five-membered ring of this component to produce water-soluble dark blue crystals, namely sodium azulene sulfonate, also known as sodium guaiazulene sulfonate, which is a derivative of sesquiterpenoid azulene compounds.

[0063] Among the above components, the friction agent is one or more of silicon dioxide, calcium hydrogen phosphate, calcium pyrophosphate, light calcium carbonate, natural zeolite, aluminum hydroxide, etc., including but not limited to spherical silica SPHERILEX®145 and ZEODENT®103 (PCR>110) imported from Germany.

[0064] In the above components, the sweetener is one or more of xylitol, sodium saccharin, sucralose, steviol glycoside, sodium cyclamate, mogroside, etc. In the above components, the foaming agent is one or more of sodium lauroyl sarcosinate, sodium lauryl sulfate, cocamidopropyl betaine, sodium lauroyl glutamate, sodium methyl cocoyl taurate, lauryl glucoside, glycolipids and lauric acid, etc.

[0065] In the above components, the thickener includes one or more of carbomer, polyquaternium salt, cellulose gum, hydroxypropyl guar gum, corrugated carrageenan, and xanthan gum.

[0066] In the above components, the pH adjuster is one or more of trisodium phosphate, tetrasodium pyrophosphate, arginine, tromethamine and citric acid.

[0067] The processes of the two different toothpastes are basically the same, including:

[0068] 1. Dissolve the water-soluble raw materials (sweeteners, stabilizers, pH adjusters) in water and moisturizers. After they are evenly dissolved, pump them into the main pot.

[0069] 2. Disperse the thickener evenly in the abrasive;

[0070] 3. Pump 2 into the main pot, and after the vacuum reaches above -0.096MPa, stir rapidly for 30 minutes;

[0071] 4. Pump the foaming agent, fragrance, and gum protection (freshening) composition into the pot and stir for 15 minutes;

[0072] 5. Discharge the material after it passes the inspection.

[0073] Performance evaluation:

[0074] Stability test

[0075] After standing for 24 hours, the samples were placed in 100 ml transparent plastic bottles and placed at -18°C (1 month), room temperature (25°C) and 50°C for 3 months, respectively, and the appearance and presence of stratification were observed.

[0076] Efficacy evaluation test data

[0077] The antibacterial experiment of fresh toothpaste-related odor-causing bacteria is as follows:

[0078] Test plan:

[0079] Dilute Fn, Pg, and Sm bacteria to appropriate concentrations and spread them on a 96-well plate, 100 μL per well, take 100 μL of positive control, 100 μL of negative control, and sample solution and add them to the 96-well plate, shake gently to mix, put the bacterial culture plate into an anaerobic bag, and culture at 37°C. After the three bacteria were cultured for a fixed time (16 h, 24 h, or 48 h), the OD was detected at 620 nm on a microplate reader.

[0080] Calculation formula:

[0081] Inhibition rate (%) = (1-OD test group / OD negative control group)

[0082] Under the conditions of this experiment, the fresh toothpaste composition has a significant inhibitory effect on the growth of halitosis-related odor-causing bacteria Fn, Pg, and Sm, and has the potential to reduce bad breath (bad breath). The experimental results are as follows: Figure 6-Figure 8 shown.

[0083] Clinical trial effect of gum protection toothpaste on inhibiting dental plaque

[0084] Compared with the control group, the average value of the Turky modified Quigley-Hein plaque index of the subjects using the test group toothpaste was 1.10, which was lower than the average value of the control group 1.68. The independent mean t-test between the two groups showed a statistically significant difference ( P < 0.01).

[0085] Quigley-Hein Plaque Index

[0086] Experimental group A (x±s) Control group B (x±s)

[0087] 1.10±0.72 1.68±0.69

[0088] Comparison of Lüe–Silness Gingival Index

[0089] At baseline, the Lüe–Silness gingival index of the experimental group and the control group was 1.36 and 1.33, respectively. There was no significant difference between the two groups by independent t-test of means (P>0.05).

[0090] After 6 weeks of the experiment, the Lüe-Silness gingival index of the experimental group decreased by 5.88% compared with the baseline, and the Lüe-Silness gingival index of the control group decreased by -2.26% compared with the baseline. The independent mean t-test between the two groups showed that p < 0.05, and the difference in gingival index between the experimental group and the control group was statistically significant.

[0091] After 12 weeks of the experiment, the Lüe-Silness gingival index of the experimental group decreased by 11.03% compared with the baseline, and the Lüe-Silness gingival index of the control group decreased by 0% compared with the baseline. The independent mean t-test between the two groups showed that p < 0.05, and the difference in gingival index between the experimental group and the control group was statistically significant.

[0092]

[0093] As shown in the above experiment, the gum protection composition toothpaste has a significant effect of inhibiting dental plaque and alleviating gingivitis.

[0094] The above description is only the preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A multi-chamber mixing extrusion tank, characterized in that: It includes a pipe body assembly and a pipe head assembly connected to the pipe body assembly; The tube body assembly is formed by splicing at least two tube body units, each of which has a tube cavity, and a mounting channel is formed on the inner side of the plurality of tube body units, and an air supply pipe corresponding to the tube body unit is arranged in the mounting channel, and a piston push plate and an airbag assembly are arranged in the tube cavity of each tube body unit, and the airbag assembly is located below the piston push plate, and the air supply pipe is connected to the airbag assembly in the corresponding tube body unit through a first one-way valve; The tube head assembly includes a tube head body, a paste outlet nozzle arranged on the tube head body, the paste outlet nozzles are respectively connected with the tube cavities of the tube body unit, a rubber pressing ball is arranged in the tube head body, an air inlet is arranged on the rubber pressing ball, a second one-way valve is arranged in the air inlet, an air outlet of the rubber pressing ball is connected with an air outlet pipeline, the air outlet pipeline is connected with all the air supply pipes through a regulating valve, and an operation key for controlling the regulating valve to change the gas flow ratio between the air supply pipes is also arranged on the tube head body; A pressing piece is also slidably provided on the tube head assembly, and the top of the rubber pressing ball is in conflict with the pressing piece; There are two tube body units, and toothpaste A and toothpaste B are respectively arranged in the tube cavities of the two tube body units. The regulating valve is a three-way regulating valve, and the operating key is a knob that is rotated on the tube head body. The knob is surrounded by ratio scales of toothpaste A and toothpaste B.

2. A multi-chamber mixed extrusion tank as claimed in claim 1, characterized in that: The tube head body is threadedly connected to the upper part of the tube body unit, the paste outlet nozzle is connected to the tube cavity of the tube body unit through a connecting hose, and the connecting hose is plugged and matched with the paste outlet of the tube body unit.

3. The multi-chamber mixed extrusion tank according to claim 1, characterized in that: The airbag component is in a continuously bent shape.

4. The multi-chamber mixed extrusion tank according to claim 1, characterized in that: The airbag assembly includes a plurality of airbag units connected in sequence.

5. The multi-chamber mixed extrusion tank according to claim 1, characterized in that: The pressing piece is a hollow structure.

6. A multi-chamber mixed extrusion tank as claimed in claim 5, characterized in that: It also includes a tube cover matched with the tube body assembly, and the tube cover is arranged above the tube head assembly.

7. A multi-chamber mixed extrusion toothpaste, characterized in that: It includes a pipe body assembly and a pipe head assembly connected to the pipe body assembly; The tube body assembly is formed by splicing two tube body units, each of which has a tube cavity, and a mounting channel is formed on the inner side of the plurality of tube body units, and an air supply pipe corresponding to the tube body unit is arranged in the mounting channel, and a piston push plate and an airbag assembly are arranged in the tube cavity of each tube body unit, and the airbag assembly is located below the piston push plate, and the air supply pipe is connected to the airbag assembly in the corresponding tube body unit through a first one-way valve; The tube head assembly includes a tube head body, a paste outlet nozzle arranged on the tube head body, the paste outlet nozzles are respectively connected with the tube cavities of the tube body unit, a rubber pressing ball is arranged in the tube head body, an air inlet is arranged on the rubber pressing ball, a second one-way valve is arranged in the air inlet, an air outlet of the rubber pressing ball is connected with an air outlet pipeline, the air outlet pipeline is connected with all the air supply pipes through a regulating valve, and an operation key for controlling the regulating valve to change the gas flow ratio between the air supply pipes is also arranged on the tube head body; A pressing piece is also slidably provided on the tube head assembly, and the top of the rubber pressing ball is in conflict with the pressing piece; The two tube units are respectively loaded with a freshening composition toothpaste and a natural gum protection composition toothpaste; The refreshing toothpaste composition comprises, by weight, 0.2-2 parts of persimmon fruit extract or emblica extract or shiitake mushroom extract, 0.01-0.5 parts of plant enzyme, 0.01-0.5 parts of complex amino acid, 0.5-3 parts of PVM / MA copolymer, 10-25 parts of abrasive, 5-66 parts of moisturizing agent, 0.1-2 parts of thickener, 0.1-5 parts of sweetener, 1-3 parts of foaming agent, appropriate amount of pH regulator and 0.1-2 parts of stabilizer, 0.5-1.5 parts of fragrance, and the rest is water; The natural gum protection composition toothpaste comprises, by weight, 0.5-5 parts of gum protection composition, 10-30 parts of abrasive, 20-66 parts of moisturizer, 0.1-2 parts of thickener, 0.1-5 parts of sweetener, 1-3 parts of foaming agent, an appropriate amount of pH regulator and 0.1-2 parts of stabilizer, 0.5-1.5 parts of fragrance, and the rest is water.

8. The multi-chamber mixed extrusion toothpaste according to claim 7, characterized in that: The gum protection composition is at least one of scutellaria baicalensis, magnolia bark extract, chamomile derivatives, dipotassium glycyrrhizinate, and perilla seed extract.

Citation Information

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