A pesticide composition for controlling the traditional Chinese medicine Cuscuta chinensis

The pesticide composition of isoxaflutole and triclopyralid has solved the problems of incomplete control and phytotoxicity of dodder in existing technologies, achieving effective control in fields of Chinese medicinal herbs, enhancing the efficacy and ensuring the safety of Chinese medicinal herbs.

CN119366525BActive Publication Date: 2025-10-28SHANDONG ACADEMY OF AGRICULTURAL SCIENCES
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Patent Information

Application Number
CN202411485101.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-10-23
Publication Date
2025-10-28
Estimated Expiration
2044-10-23

AI Technical Summary

Technical Problem

Current technology lacks chemical agents that can effectively and safely control dodder. Chemical herbicides can easily cause phytotoxicity to Chinese medicinal herbs, and dodder endangers the safety of Chinese medicinal herb cultivation.

Method used

A pesticide composition of isoxaflutole and triclopyralid in a mass ratio of (20-40):3 is used to control dodder in Chinese medicinal fields. The formulations include suspension concentrate, oil suspension, and wettable powder, and it is sprayed on the stems and leaves of dodder.

Benefits of technology

It effectively controls dodder, reduces dodder damage in medicinal herb fields, significantly enhances efficacy, and is safe for medicinal herbs, thus possessing the potential to be commercialized as a pesticide.

✦ Generated by Eureka AI based on patent content.

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Abstract

This invention belongs to the field of agricultural weed control technology, and relates to a pesticide composition for controlling the traditional Chinese medicine dodder. The composition contains isoxaflutole and triclopyralid, with a triclopyralid:isoxaflutole mass ratio of 3:(20-40). When used to control dodder in the traditional Chinese medicine Cynanchum paniculatum, the dosage of isoxaflutole is 72-144 g ai / hm. 2 The dosage of triclopyralid is 10.8 g ai / hm. 2 The drug combination screened by this invention has good safety for the traditional Chinese medicine Cynanchum paniculatum and excellent effect in preventing and controlling Cuscuta chinensis.
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Description

Technical Field

[0001] This invention belongs to the field of agricultural weed control technology and relates to a pesticide composition for controlling dodder. Background Technology

[0002] The information disclosed in this background section is intended to enhance understanding of the overall background of the invention and is not necessarily to be construed as an admission or in any way implying that such information constitutes prior art known to those skilled in the art.

[0003] Cuscuta belongs to the genus Cuscuta in the family Convolvulaceae (Cuscuta). Cuscuta sp. Dodder (Cuscuta chinensis) is a general term for a type of highly destructive parasitic weed. It uses a specialized, modified organ called a "haustorium" to absorb nutrients from its host plant. Dodder cannot survive outside its host plant, and through long-term evolution and rapid spread, it can now parasitize over a thousand plant species. Dodder is widely distributed in many provinces of my country, including Heilongjiang, Gansu, Shandong, Jiangsu, Hunan, Hubei, Jiangxi, and Guangdong, posing a serious threat to the growth of various crops and medicinal herbs.

[0004] On the other hand, dodder seed, as a traditional Chinese medicine, has rich medicinal value, and its medicinal history can be traced back to ancient times. It was first recorded in the *Shennong Bencao Jing* (Shennong's Classic of Materia Medica), and in its medicinal history, it has also been known by various names such as *tu lu*, *tu lu*, *tu lei*, and *tu qiu*. my country has a long history of cultivating and using dodder seed medicinally. However, in recent years, with the development of my country's traditional Chinese medicine industry, the artificial cultivation area of ​​dodder seed and other Chinese medicinal herbs has gradually increased, leading to a year-on-year increase in the harmful effects of dodder seed on farmland. In major Chinese medicinal herb cultivation bases such as Gansu, Shandong, and Shaanxi provinces, dodder seed seriously threatens the cultivation safety of other Chinese medicinal herbs.

[0005] Chemical herbicides have made significant contributions to controlling weed damage in farmland, increasing crop yields, and ensuring food security. However, dodder is extremely resilient and easily forms a close parasitic relationship with its host. The incorrect application of chemical herbicides can easily cause phytotoxicity to the host plant. Currently, there is a lack of chemical agents that can effectively and safely control dodder. Summary of the Invention

[0006] To address the lack of pesticides for controlling dodder, this invention provides a pesticide composition for controlling dodder, which can effectively control dodder and has high safety for traditional Chinese medicine.

[0007] To achieve the above objectives, the present invention adopts the following technical solution.

[0008] A pesticide composition for controlling dodder includes isoxaflutole and triclopyralid.

[0009] The mass ratio of isoxaflutole to triclopyralid is (20-40):3.

[0010] The crop for which the pesticide composition is applied is Cynanchum paniculatum.

[0011] The above composition may also contain other inert components for stabilizing the active ingredient, making it easier to apply to crops or adhere to targets, such as fillers, wetting agents, dispersants, defoamers, antifreeze agents, solvents, emulsifiers, preservatives, disintegrants, etc.

[0012] The above-mentioned compositions can be processed into formulations using methods commonly used in the prior art. Preferred dosage forms include suspensions, oil suspensions, microcapsule suspensions, wettable powders, water-dispersible granules, emulsifiable concentrates, and microemulsions.

[0013] A method for controlling dodder in traditional Chinese medicine fields includes the following steps:

[0014] A mixture of isoxaflutole and triclopyralid was sprayed onto the stems and leaves of Cuscuta chinensis.

[0015] The mass ratio of isoxaflutole to triclopyralid is (20-40):3;

[0016] The medicinal herb grown in the field is Cynanchum paniculatum.

[0017] The dosage of isoxaflutole used was 72 g / hm. 2 -144g / hm 2 The dosage of triclopyralid is 10.8 g / hm. 2 .

[0018] The endpoints and any values ​​of the ranges disclosed in this application are not limited to the precise ranges or values, and these ranges or values ​​should be understood to include values ​​close to these ranges or values. For numerical ranges, the endpoint values ​​of the various ranges, the endpoint values ​​of the various ranges and individual point values, and individual point values ​​can be combined with each other to obtain one or more new numerical ranges, which should be considered as specifically disclosed in this application.

[0019] The present invention has the following advantages:

[0020] Currently, the market lacks highly effective pesticides for controlling dodder. The pesticide combination provided by this invention can effectively control dodder while ensuring the safety of traditional Chinese medicine, thereby effectively reducing the damage caused by dodder in herb fields. Furthermore, this combination of two pesticides exhibits significant synergistic effects and ensures safety, demonstrating its great potential for development into a commercial pesticide. Attached Figure Description

[0021] Figure 1 Illustration of the damage caused by dodder to the Chinese herbal medicine Xu Changqing;

[0022] Figure 2This diagram illustrates the control effects of isoxaflutole and triclopyralid on Cuscuta chinensis. Detailed Implementation

[0023] The present invention will be further described below with reference to the embodiments, but the present invention is not limited to the following embodiments.

[0024] Example 1: Screening of highly effective agents for controlling dodder

[0025] 1. Single-agent screening

[0026] Test plot: The previous crop of Cuscuta chinensis was selected from the medicinal field of Cynanchum paniculatum.

[0027] The tested herbicides included 21 products: quizalofop-P-ethyl, acetochlor, pendimethalin, 2,4-D isooctyl ester, prochloraz, triclopyralid, flusulfanilamide, propyzamide, butachlor, bentazon, nicotinic acid, trifluralofop-P-ethyl, succinyl acetochlor, trifluralin, methyl methacrylate, trifluralin, dicamba, imazalil nicotinic acid, isoxaflutole, metribuzin, and quinclorac. All herbicides were commercially available formulations.

[0028] Dosage and application method: The minimum amount recommended for field application as stated on the pesticide formulation label;

[0029] The system uses an ASS-4 type automatic control spraying system with fan-shaped nozzles, a spray pressure of 0.4MPa, and a nozzle flow rate of 800mL / min. The operating speed is adjusted according to the actual spraying area to ensure uniform spraying.

[0030] Results survey: On the 15th day after application, three points were randomly selected from each plot, and the stem tip condition of 20 dodder plants was randomly surveyed within the selected area. The survival rate was recorded, and the control effect was calculated using the following formula:

[0031] Control effect (%) = (Surviving stem tips of dodder in the control area - Surviving stem tips of dodder in the treatment area) / Surviving stem tips of dodder in the control area × 100.

[0032] A random survey of the growth status of 100 crop plants was conducted, and the extent of herbicide damage to Cynanchum paniculatum was recorded according to the following criteria:

[0033] No impact on growth is recorded as "Level I"; impact on growth but no plant death is recorded as "Level II"; severe impact on growth and death of more than 50% of plants is recorded as "Level III"; total plant death is recorded as "Level IV".

[0034] Table 1. Control efficacy of different agents against dodder and safety against Cynanchum paniculatum

[0035]

[0036] Note: "-" is invalid, and " / " was not included in the statistics.

[0037] As shown in Table 1, the 22 selected herbicides showed significant differences in their efficacy against dodder. However, the herbicides with 100% efficacy, such as acetochlor, triclopyralid, metribuzin, 2,4-D isooctyl ester, and terbufotazone, all had a devastating impact on the host herb (Cynanchum paniculatum). In subsequent experiments, even after reducing the concentration of the herbicides (diluting them 5 times), the occurrence of phytotoxicity was still not effectively reduced.

[0038] Isoxaflutole was screened for further research based on a comprehensive consideration of factors such as safety, efficacy, overall control effect, and mechanism of action. Since dodder germinates relatively quickly, its combination with a highly effective hormone-based herbicide that inhibits apical growth may yield better results. Apical inhibition experiments with this type of herbicide showed that triclopyralid, even at 0.1 times the field concentration, still had a good apical inhibition effect on dodder. Therefore, isoxaflutole and triclopyralid will be the subjects of further research.

[0039] 2. Screening of Traditional Chinese Medicine Agents with Specific Control Effects on Cuscuta chinensis

[0040] Using the same operating method as in step 1, formulation screening was conducted by compounding commercially available 480 g / L triclopyralid emulsifiable concentrate and 480 g / L isoxaflutole emulsifiable concentrate.

[0041] Table 2. Control efficacy of different doses of isoxaflutole and triclopyralid against dodder and safety against Cynanchum paniculatum.

[0042]

[0043] As shown in Table 2, the combination of isoxaflutole and triclopyralid has a good effect on the traditional Chinese medicine Cuscuta chinensis, and the combined effect is a significant synergistic effect. Based on ensuring safety, isoxaflutole 72-144 g a.i. / hm is recommended. 2 and triclopyralid 10.8 g ai / hm 2 The compound formulation is triclopyralid:isoxamethasone at a ratio of 3:(20-40).

[0044] The above description is merely an embodiment of this application and is not intended to limit the scope of this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the scope of the claims of this application.

Claims

1. A pesticide composition for controlling dodder, characterized in that, The active ingredients consist of isoxaflutole and triclopyralid; The dosage of isoxaflutole used was 72 g ai / hm. 2 -144g ai / hm 2 The dosage of triclopyralid is 10.8 g ai / hm. 2 .

2. The pesticide composition according to claim 1, characterized in that, It also contains other inert components selected from at least one of fillers, wetting agents, dispersants, defoamers, antifreeze agents, solvents, emulsifiers, preservatives, and disintegrants.

3. The pesticide composition according to claim 1, characterized in that, The dosage form is selected from suspension concentrates, oil suspension concentrates, microcapsule suspension concentrates, wettable powders, water-dispersible granules, emulsifiable concentrates, or microemulsions.

4. A method for controlling dodder in medicinal herb fields, characterized in that, Includes the following steps: A mixture of isoxaflutole and triclopyralid was sprayed onto the stems and leaves of Cuscuta chinensis. The dosage of isoxaflutole used was 72 g ai / hm. 2 -144g ai / hm 2 The dosage of triclopyralid is 10.8 g ai / hm. 2 ; The medicinal herb grown in the field is Cynanchum paniculatum.

Citation Information

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