A low impedance electrode patch and its preparation method and application

Abstract

The present invention provides a low-impedance electrode patch and a preparation method and application thereof, wherein the low-impedance electrode patch comprises an insulating area, an electrode area and a lead connection area, wherein the electrode area is a low-impedance electrode material prepared from fructose, MXene, PEDOT:PSS and waterborne polyurethane, the insulating area is a medical non-woven fabric, and the lead connection area is a silver button. The low-impedance electrode patch provided by the present invention has high conductivity, good flexibility, stretchability, good adhesion to the skin, and stable signal after long-term use. It can be seamlessly bonded to the skin surface, so that the skin and the electrode material present low impedance characteristics. The present invention has a simple process and is easy to manufacture. Compared with traditional silver chloride electrodes, it can detect signals with a higher signal-to-noise ratio, and the signal attenuation is weak during long-term detection.

Description

Technical Field

[0001] The present invention belongs to the field of biomedical technology, and in particular relates to a low-impedance electrode patch and a preparation method and application thereof. Background Art

[0002] Human life activities are driven by a variety of biopotentials. Monitoring biopotential signals, such as ECG and EEG, can provide us with a lot of important health information. For example, ECG signals can provide important information about the heart condition, so ECG is widely used in the diagnosis of cardiovascular diseases such as arrhythmia; EEG signals can provide key information for neurological diseases such as Parkinson's disease.

[0003] Through electrode patches, we can monitor ECG and EEG signals. Ag / AgCl gel electrodes dominate clinical practice, but in long-term continuous monitoring, the evaporation of the liquid in the gel electrolyte can easily lead to signal attenuation and skin irritation. At the same time, when there is sweat on the human body surface, the electrode patch easily loses its stickiness, thereby increasing the contact impedance. Therefore, it is crucial to develop a low-impedance and highly adhesive electrode patch for wearable ECG and EEG measurements.

[0004] Patent document CN118366697A discloses a highly conductive flexible thin film electrode and its preparation method and application. The highly conductive flexible thin film electrode uses PEDOT:PSS as raw material, and is prepared by adding a two-dimensional material MXene aqueous solution and an elastic material waterborne polyurethane WPU to prepare a solution, stirring it, and then putting it into a vacuum drying oven to dry it and then taking it out. The obtained film has excellent flexibility and stretchability, as well as good conductivity. However, the thin film electrode lacks research on adhesion and other aspects. As a wearable device, the adhesion and impedance between it and human skin, detection performance and other aspects are unknown.

[0005] Therefore, providing an electrode patch with good conductivity and stretchability, strong adhesion and good detection performance is of great significance in electrocardiogram, electroencephalogram detection and sports management. Summary of the invention

[0006] The technical problem to be solved by the present invention is to overcome the deficiencies existing in the above-mentioned prior art and provide a low-impedance stretchable ECG and EEG electrode patch, which has the advantages of high conductivity, good flexibility, stretchability, good adhesion to the skin, and stable signals after long-term use.

[0007] To achieve the above object, the present invention adopts the following technical solutions:

[0008] In one aspect, the present invention provides a low-impedance electrode patch comprising an electrode region of a low-impedance electrode material, wherein the low-impedance electrode material comprises fructose, MXene, and PEDOT:PSS.

[0009] In the prior art, Ag / AgCl is usually used as an electrode patch material in devices for measuring ECG signals, and the electrical signals are enhanced by conductive gel. However, these materials can be uncomfortable, irritating to the skin, and easy to dry. In the application publication number CN118366697A, the invention name is "A highly conductive flexible thin film electrode and its preparation method and application", a thin film electrode with softness and stretchability is prepared by using highly conductive materials MXene and PEDOT:PSS and adding water-based polyurethane. The mass ratio of PEDOT:PSS, MXene and water-based polyurethane described in the application is 2:1:0.4~0.8. When the solid content ratio of MXene and PEDOT:PSS remains unchanged, the stretchability of the film varies between 600% and 810% as the content of water-based polyurethane changes. However, the thin film electrode uses PEDOT:PSS as its main component, and the electrode has limited stretchability. When used as a wearable device, the electrode mainly relies on the flexibility of the water-based polyurethane molecular chain segments to fill the skin microstructure and adhere to the skin, but the adhesion between the electrode and the skin is poor.

[0010] In the prior art, when polymer materials are used to prepare electrode films or patches, the water-based polyurethane raw materials are mainly used to increase the adhesion of the materials. However, the adhesion of existing electrode materials is average and they are prone to fall off when in contact with the skin. The stratum corneum of the skin is mainly composed of some aged keratin. If the electrode film can form hydrogen bonds with the skin surface, the microscopic adhesion can be improved. Common hydrogen bonds are mainly carboxyl (acidic), amino (alkaline), hydroxyl and ester bonds, etc. Among them, only hydroxyl (neutral) is biosafe, so it is preferred to use substances containing hydroxyl to improve the adhesion of electrode films.

[0011] Common substances containing more hydroxyl groups include sugars, glycerol and alcohols. Therefore, in some embodiments, the present invention verifies the necessity of using sugars to prepare low-impedance electrode patches. The results show that the electrode patches prepared by using hexanediol (diol) and glycerol (triol) are not as good as the electrode patches prepared by fructose in terms of conductivity and adhesion to the skin. Therefore, the present invention uses MXene, PEDOT:PSS and water-based polyurethane to prepare electrode patches that can be used for electrocardiogram and electroencephalogram detection. Sugar substances are creatively added to the mixed solution of these three materials, and sugar substances are used to plasticize PEDOT:PSS. When the electrode is stretched (<40% deformation), the electrical properties itself do not change significantly, which reduces the interference caused by the deformation of the electrode itself; at the same time, sugars enhance the adhesion of the entire solution, and sugar molecules form hydroxyl groups on the surface of the prepared electrode patch film, increasing the force between the film and the skin. Therefore, the electrode patch provided by the present invention not only has good stretchability, can fit firmly and stably with the skin, but also improves the stability and conductivity of the electrical signal.

[0012] In addition, the present invention has proved through research that in the preparation process of low-impedance electrode materials, increasing the proportion of MXene can significantly reduce the impedance of the electrode material.

[0013] Preferably, adding fructose to the raw materials for preparing the low-impedance electrode material can significantly improve the conductivity of the electrode patch and its adhesion to the skin.

[0014] Furthermore, the low-impedance electrode material also includes water-based polyurethane.

[0015] Furthermore, the mass ratio of fructose, MXene, PEDOT:PSS and waterborne polyurethane is (0.1~10):(0.1~10):(10~50):(30~70).

[0016] Preferably, the mass ratio of fructose, MXene, PEDOT:PSS and aqueous polyurethane is (0.1-5):(0.1-5):(20-40):(40-50).

[0017] Furthermore, an organic solvent is added to the PEDOT:PSS, and the organic solvent includes one or more of ethylene glycol, glycerol, isopropanol, and dimethyl sulfoxide.

[0018] In some embodiments, adding an organic solvent to the PEDOT:PSS solution can further improve the conductivity of the PEDOT:PSS, thereby reducing the impedance of the electrode patch.

[0019] Furthermore, the mass ratio of the PEDOT:PSS to the organic solvent is 1:(0.01-0.2).

[0020] Preferably, the mass ratio of the PEDOT:PSS to the organic solvent is 1:(0.01-0.05).

[0021] Furthermore, the electrode patch also includes an insulating area and a lead connection area.

[0022] In some embodiments, the insulating area is a medical non-woven fabric, and the lead connection area is a silver button.

[0023] Furthermore, the lead connection area is fixed in the insulating area, and the electrode area is adhered to the insulating area and contacts the lead connection area.

[0024] In some methods, a silver button is fixed in a through hole of a medical non-woven fabric of a certain size, and a low-impedance electrode material is cut into a certain size and adhered to the other side of the medical non-woven fabric so as to contact the silver button.

[0025] In some embodiments, the diameter of the medical nonwoven fabric is 2 to 10 cm, and the diameter of the low-impedance electrode material is 1 to 8 cm.

[0026] Preferably, the diameter of the medical non-woven fabric is 2-4 cm, and the diameter of the low-impedance electrode material is 1-2.5 cm.

[0027] In another aspect, the present invention provides a method for preparing a low-impedance electrode material, comprising the following steps:

[0028] (1) Mix the PEDOT:PSS solution with the aqueous polyurethane and mix them evenly by vigorous stirring;

[0029] (2) adding the MXene solution to the mixed solution obtained in step (1), and mixing them uniformly by vigorous stirring;

[0030] (3) adding the fructose solution to the mixed solution obtained in step (2), and mixing them evenly by vigorous stirring;

[0031] (4) The mixed solution obtained in step (3) is heated statically, and a low-impedance electrode material is obtained after the water is completely evaporated.

[0032] In some embodiments, the PEDOT:PSS solution in step (1) is obtained by adding an organic solvent to a PEDOT:PSS dispersion and stirring. The solid content of the PEDOT:PSS in the dispersion is 0.1-5%, the mass fraction of the organic solvent in the mixed solution is 0.001%-1%, the stirring temperature is 10-30°C, the stirring speed is 100-800 rpm, and the stirring time is 10-120 min.

[0033] In some embodiments, the solid content of the waterborne polyurethane is 1-50%.

[0034] In some embodiments, the organic solvent includes one or more of ethylene glycol, glycerol, isopropanol, and dimethyl sulfoxide. In a preferred embodiment of the present invention, ethylene glycol is selected.

[0035] In some embodiments, the preparation method of the MXene solution in step (2) is to first slowly add LiF into hydrochloric acid and stir for 30 min; then add Ti 3 AlC 2 The powder was slowly added to the solution and stirring was continued for 24 h. The solution was further centrifuged repeatedly and washed with deionized water until the pH of the supernatant was greater than 5. The precipitate obtained was the MXene slurry. Finally, the MXene slurry was dissolved in deionized water to obtain a MXene solution.

[0036] In some embodiments, the solid content of the MXene solution is 0.1-10%.

[0037] In some embodiments, the solid content of the fructose solution in step (3) is 0.1-10%.

[0038] Furthermore, the stirring temperature in steps (1) to (3) is 10 to 30° C., the stirring speed is 100 to 800 rpm, and the heating temperature in step (4) is 40 to 90° C.

[0039] Preferably, the stirring temperature in steps (1) to (3) is 25°C, the stirring speed is 500 rpm, and the heating temperature in step (4) is 60°C.

[0040] Compared with the prior art, the present invention has the following beneficial effects:

[0041] 1. The low-impedance electrode patch provided by the present invention has high conductivity, good flexibility, stretchability, good adhesion to the skin, and stable signal after long-term use;

[0042] 2. Low impedance electrode patches have good skin compliance and low contact impedance, and can be used to obtain high-quality ECG and EEG signals under various skin conditions (including dry and wet conditions);

[0043] 3. The process of the present invention is simple and easy to manufacture. Compared with the traditional Ag / AgCl electrode patch, it can detect signals with a higher signal-to-noise ratio, and the signal attenuation is weak during long-term detection. It has a wide range of application prospects in electrocardiogram and electroencephalogram detection and sports management. BRIEF DESCRIPTION OF THE DRAWINGS

[0044] In order to more clearly illustrate the technical solutions of the exemplary embodiments of the present invention, the following is a brief introduction to the drawings required for use in the embodiments. It should be understood that the following drawings only illustrate certain embodiments of the present invention and should not be regarded as limiting the scope. For those of ordinary skill in the art, other relevant drawings can be obtained based on these drawings without creative work.

[0045] Figure 1 This is a photograph showing the low-impedance electrode material prepared in the present invention adhering to the skin.

[0046] Figure 2 This is a physical picture of the electrode patch prepared by the present invention.

[0047] Figure 3 This is a comparison diagram of the contact impedance between the electrode patch of the present invention and the skin.

[0048] Figure 4 This is a comparison diagram of the electrocardiogram signal monitored by the electrode patch of the present invention and the commercial silver / silver chloride electrode. DETAILED DESCRIPTION

[0049] In order to make the above-mentioned objectives, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with embodiments and drawings. The exemplary implementation modes of the present invention and their description are only used to explain the present invention and are not intended to limit the present invention.

[0050] Unless otherwise specified, the raw materials used in the examples were purchased commercially.

[0051] Example 1: Preparation of low impedance electrode material provided by the present invention

[0052] (1) Preparation of MXene solution

[0053] S1. Slowly add 0.5 g LiF (purchased from Shanghai Aladdin Biochemical Technology Co., Ltd., model L104224) into 40 ml 9 M hydrochloric acid (purchased from Sinopharm Chemical Reagent Co., Ltd., model 10011028) and stir at 400 rpm in a polytetrafluoroethylene beaker for 30 min;

[0054] S2. 0.5g Ti 3 AlC 2 The powder (purchased from Jilin Yiyi Technology Co., Ltd., model YY201701) was slowly added to the above solution and stirred at 400 rpm for 24 h.

[0055] S3. The above solution is repeatedly centrifuged and washed with deionized water until the pH of the supernatant is greater than 5, and then the supernatant is removed, and the precipitate is the MXene slurry;

[0056] S4. Dissolve the above MXene slurry in 30 mL of deionized water to obtain a MXene solution with a mass fraction of 10%.

[0057] (2) Preparation of low impedance electrode materials

[0058] S1. Add 50 μl of ethylene glycol (purchased from Shanghai MacLean Biochemical Technology Co., Ltd., model E808735) to 1 ml of 1.3% PEDOT:PSS (purchased from Heraeus, Germany, model PH1000) solution, and stir at 25°C for 1 h to mix well.

[0059] S2. Add 481 μl of 10% waterborne polyurethane solution (purchased from Anhui Chunxiao Chemical Co., Ltd., model WPU517) to the above solution and stir at 25 degrees Celsius for 1 h to mix well.

[0060] S3. Add 6.5 μl of the MXene solution prepared in step (1) to the above solution, and stir at 25°C for 1 h to mix well;

[0061] S4. Add 32.5 μl of 10% fructose solution (purchased from Shanghai MacLean Biochemical Technology Co., Ltd., model F875004) to the above solution, stir at 25°C for 1 h to mix evenly, and obtain a low-impedance electrode material solution;

[0062] S5. The prepared low-impedance electrode material solution is introduced into the mold and heated on a hot plate at 60°C for 2 h to evaporate the water in the mixed solution to obtain a low-impedance electrode material, such as Figure 1 As shown, named PMWF-1%.

[0063] Example 2: Adding glucose

[0064] According to the component ratio and preparation method of Example 1, the fructose solution in S3 of step (2) was replaced with a glucose solution (purchased from Sinopharm Chemical Reagent Co., Ltd., model SD9434250G) to prepare a low-impedance electrode material named PMWG.

[0065] Example 3: Adding sucrose

[0066] According to the component ratio and preparation method of Example 1, the fructose solution in S3 of step (2) was replaced with a sucrose solution (purchased from Sinopharm Chemical Reagent Co., Ltd., model number 10021463) to prepare a low-impedance electrode material named PMWS.

[0067] Example 4: Adding maltose

[0068] According to the component ratio and preparation method of Example 1, the fructose solution in S3 of step (2) was replaced with maltose (purchased from Shanghai Sinopharm Reagent Group Co., Ltd., model 63008534) solution to prepare a low impedance electrode material named PMWM.

[0069] Example 5: No added sugars

[0070] (1) Preparation of MXene solution

[0071] The composition ratio and preparation method are the same as those in Example 1.

[0072] (2) Preparation of low impedance electrode materials

[0073] S1. Add 50 μl of ethylene glycol to 1 ml of 1.3% PEDOT:PSS solution and stir at 25°C for 1 h to mix well.

[0074] S2. Add 513.5 μl of 10% aqueous polyurethane solution to the above solution and stir at 25 degrees Celsius for 1 h to mix well.

[0075] S3. Add 6.5 μl of the MXene solution prepared in step (1) to the above solution, stir at 25° C. for 1 h to mix evenly, and obtain a low-impedance electrode material solution;

[0076] S4. The prepared low-impedance electrode material solution was introduced into the mold and heated on a hot plate at 60°C for 2 h to evaporate the water in the mixed solution to obtain a low-impedance electrode material, named PMW.

[0077] Example 6: Performance test of low impedance electrode patch

[0078] After screening and comparing the performance of electrode patches made of different hydroxyl-containing substances, it was found that the electrode patches made of sugar substances can not only adhere firmly and stably to the skin, but also improve the stability of electrical signals. Therefore, this example further compares and verifies the electrode patches made of different sugars.

[0079] (1) Mechanical properties test of low impedance electrode materials

[0080] The low-impedance electrode materials prepared according to Examples 1 to 5 were subjected to mechanical property tests according to GB / T 2105-1991 standard, and to 90-degree peeling tests according to GB / T 2792-2014 standard. The test results are shown in Table 1.

[0081] Table 1 Mechanical properties test results of low impedance electrode materials

[0082]

[0083] As shown in Table 1, compared with the existing Ag / AgCl electrode material (control), the low-impedance electrode material prepared from MXene, PEDOT:PSS and waterborne polyurethane materials has a higher tensile stress, but Ag / AgCl is a hydrogel wet electrode, and the water in the gel material is volatile and unstable, and is not used as a long-term wear electrode. At the same time, by comparing Examples 1 to 5, it can be seen that adding sugar substances to the three materials of MXene, PEDOT:PSS and waterborne polyurethane can further reduce the tensile stress of the low-impedance electrode material, thereby improving the stretchability. The tensile properties and adhesion of the low-impedance electrode materials prepared from different sugar substances are different. The low-impedance electrode material prepared using fructose (Example 1) as a raw material has better stretchability and higher adhesion.

[0084] (2) Low impedance electrode patch performance test

[0085] The low-impedance electrode materials prepared in Examples 1 to 5 were cut into circles with a diameter of 3 cm, and after cutting, they were adhered to medical non-woven fabrics with a diameter of 6 cm embedded with silver buttons to obtain low-impedance electrode patches ( Figure 2 ). The skin impedance performance of the low-impedance electrode patch was tested, and the three patches were attached to the arm as the working electrode, counter electrode, and reference electrode. The AC impedance of 1-10000 Hz was measured using an electrochemical workstation. The ECG monitoring performance was tested using a three-lead ECG monitor. The test results are shown in Table 2.

[0086] Table 2 Low impedance electrode patch performance test

[0087]

[0088] As shown in Table 2, compared with the control, the low-impedance electrode patches (groups 1 to 5) made of MXene, PEDOT:PSS and waterborne polyurethane materials have lower impedance and better conductivity. At the same time, compared with groups 1 to 5, it is found that adding sugar substances can further reduce the impedance of the electrode patch and improve the signal-to-noise ratio. Among them, the electrode patch with fructose added has the best conductivity and a higher signal-to-noise ratio. Figure 4 As shown, it can be found that the low-impedance electrode patch provided by the present invention has a better signal-to-noise ratio. Therefore, the low-impedance electrode patch prepared by fructose, MXene, PEDOT:PSS and water-based polyurethane is preferred.

[0089] Example 7: No MXene added

[0090] S1. Add 50 μl of ethylene glycol into 1 ml of 1.3% PEDOT:PSS solution and stir at 25°C for 1 h to mix well.

[0091] S2. Add 487.5 μl of 10% aqueous polyurethane solution to the above solution and stir at 25°C for 1 h to mix well.

[0092] S3. Add 32.5 μl of 10% fructose solution to the above solution, stir at 25°C for 1 h to mix evenly, and obtain a low-impedance electrode material solution.

[0093] S4. The prepared low-impedance electrode material solution was introduced into the mold and heated on a hot plate at 60°C for 2 h to evaporate the water in the mixed solution to obtain a low-impedance electrode material named PMWF-0%.

[0094] Example 8: Adding 0.25% MXene

[0095] (1) Preparation of MXene solution

[0096] The composition ratio and preparation method are the same as those in Example 1.

[0097] (2) Preparation of low impedance electrode materials

[0098] S1. Add 50 μl of ethylene glycol to 1 mL of 1.3% PEDOT:PSS solution and stir at 25°C for 1 h to mix well.

[0099] S2. Add 485.9 μl of 10% aqueous polyurethane solution to the above solution and stir at 25°C for 1 h to mix well.

[0100] S3. Add 1.6 μl of the MXene solution prepared in step (1) to the above solution and stir at 25°C for 1 h to mix well.

[0101] S4. Add 32.5 μl of 10% fructose solution to the above solution, stir at 25°C for 1 h to mix well, and obtain a low-impedance electrode material solution.

[0102] S5. The prepared low-impedance electrode material solution was introduced into the mold and heated on a hot plate at 60°C for 2 h to evaporate the water in the mixed solution to obtain a low-impedance electrode material named PMWF-0.25%.

[0103] Example 9: Effect of MXene content on the performance of low impedance electrode patches

[0104] The low impedance electrode materials prepared in Examples 1, 7, and 8 were tested for mechanical properties respectively; and low impedance electrode patches were prepared according to the method of Example 6, and skin impedance performance tests and electrocardiogram monitoring performance tests were performed respectively. The results are shown in Tables 3 and 4.

[0105] Table 3 Effect of MXene content on the mechanical properties of low impedance electrode materials

[0106]

[0107] By comparing Examples 1, 7, and 8, it can be seen that increasing the MXene content can improve the adhesion of the low-impedance electrode material. When the MXene content is 1%, the adhesion of the low-impedance electrode material is higher.

[0108] Table 4 Effect of MXene content on the performance of low impedance electrode patch

[0109]

[0110] As shown in Table 4, by comparing groups 1, 7, 8 and the control, it can be seen that increasing the content of MXene can improve the conductivity of the low-impedance electrode patch. When the content of MXene is 1%, the conductivity of the low-impedance electrode material is the best, the signal-to-noise ratio is high, and the performance of the obtained electrode patch is better than that of the commercial Ag / AgCl electrode ( Figure 3 ). In summary, the low impedance electrode patch prepared in Example 1 is preferred.

[0111] Example 10: Screening of substrate materials

[0112] Generally speaking, the base material for making electrode patches is crucial to the performance of the equipment. First, the electrode patches need to be able to adhere firmly to the skin or tissue surface to reduce fault signals and improve the authenticity of the detection signal; secondly, suitable stretchability and high conductivity are very important. Therefore, in order to further compare the differences in adhesion, conductivity and signal-to-noise ratio of electrode patches made of different base materials, and screen out the best material combination for preparing low-impedance electrode patches, this embodiment provides several combinations of preparation raw materials as shown in the following table, and low-impedance electrode materials are prepared according to the preparation method provided in Example 1, and the mechanical properties are tested respectively; then, low-impedance electrode patches are prepared according to the method of Example 6, and skin impedance performance tests and electrocardiogram monitoring performance tests are performed respectively. The results are shown in Tables 5 and 6.

[0113] Table 5 Mechanical properties test of different combinations of low impedance electrode materials

[0114]

[0115] Table 6 Performance test of different combinations of low impedance electrode patches

[0116]

[0117] As shown in Tables 5 and 6, compared with the control, the low-impedance electrode material made of polymer materials has better stretchability, stronger adhesion, and higher conductivity and signal-to-noise ratio of the electrode patch. At the same time, by comparing combinations 1-5, it can be seen that the performance of the electrode material and the patch is reduced in the absence of any of the polymers MXene, PEDOT:PSS, fructose or aqueous polyurethane. In the absence of aqueous polyurethane material, although the conductivity of the electrode patch is improved and the interfacial impedance is reduced, the electrode material has no elasticity and cannot be stretched, so it is easy to crack, and the adhesion is also reduced.

[0118] Because the electrode film prepared by hydroxyl-containing substances can form hydrogen bonds with the skin surface to improve the microscopic adhesion of the film, this embodiment also compares the performance differences of electrode patches prepared by combining different hydroxyl-containing substances with MXene, PEDOT:PSS, and waterborne polyurethane. At the same time, by comparing combinations 1, 8, and 9, it was found that after replacing the fructose molecules with hexanediol (diol) or glycerol (triol) materials, the tensile properties of the obtained electrode material changed little, but the adhesion became worse; at the same time, the impedance between the electrode patch and the skin interface increased, and the conductivity decreased. The reason may be that the sugar molecules themselves contain more hydroxyl groups, and more hydroxyl groups are formed on the surface of the prepared electrode patch film, which increases the force between the film and the skin.

[0119] By comparing combinations 1, 6, 7, and 10, it can be seen that after replacing MXene with graphene oxide (combination 6) or PEDOT:PSS with polyvinyl alcohol (combination 7), the impedance of the obtained low-impedance electrode patch increased significantly and the conductivity decreased significantly; after replacing waterborne polyurethane with polyester material (combination 8), the adhesion of the low-impedance electrode material deteriorated. In summary, the low-impedance electrode patch prepared by fructose, MXene, PEDOT:PSS and waterborne polyurethane is preferred.

[0120] Finally, it should be noted that the terms "comprises," "includes," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements that are inherent to such process, method, article, or apparatus.

[0121] Although the preferred embodiments of the present invention have been described, those skilled in the art may make other changes and modifications to these embodiments once they have learned the basic creative concept. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments and all changes and modifications that fall within the scope of the present invention.

[0122] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A composition for preparing a low-impedance electrode material that reduces the impedance of an electrode patch and improves stretchability, adhesion and the signal-to-noise ratio of electrocardiogram monitoring, characterized in that: The composition consists of fructose, MXene, PEDOT:PSS and aqueous polyurethane. The low-impedance electrode material consists of fructose, MXene, PEDOT:PSS and aqueous polyurethane. Ethylene glycol is added to the PEDOT:PSS in the low-impedance electrode material. The mass ratio of fructose, MXene, PEDOT:PSS and aqueous polyurethane is (0.1-10): (0.01-5): (1-50): (30-80). The mass ratio of PEDOT:PSS to ethylene glycol is 1: (0. 01~0.2); The preparation method of the low-impedance electrode material comprises the following steps: (1) adding ethylene glycol to the PEDOT:PSS solution and mixing it with aqueous polyurethane, and stirring them vigorously to make the mixture uniform; (2) adding the MXene solution to the mixed solution obtained in step (1), and stirring them vigorously again to make the mixture uniform; (3) then adding the fructose solution to the mixed solution, and stirring them vigorously to make the mixture uniform; (4) heating the mixed solution obtained in step (3) statically, and waiting for the water to completely evaporate to obtain the low-impedance electrode material.

2. A low impedance electrode material, characterized in that: The low-impedance electrode material is composed of fructose, MXene, PEDOT:PSS and waterborne polyurethane, and ethylene glycol is added to the PEDOT:PSS in the low-impedance electrode material; the mass ratio of fructose, MXene, PEDOT:PSS and waterborne polyurethane is (0.1-10): (0.01-5): (1-50): (30-80), and the mass ratio of PEDOT:PSS to ethylene glycol is 1: (0.01-0.2); the preparation method of the low-impedance electrode material comprises the following steps: (1) adding ethylene glycol to the PEDOT:PSS solution and then mixing it with the waterborne polyurethane, and stirring them vigorously to make them uniform; (2) adding the MXene solution to the mixed solution obtained in step (1), and stirring them vigorously again to make them uniform; (3) then adding the fructose solution to the mixed solution, and stirring them vigorously to make them uniform; (4) statically heating the mixed solution obtained in step (3), and waiting for the water to completely evaporate to obtain the low-impedance electrode material.

3. A method for preparing a low-impedance electrode material as claimed in claim 2, characterized in that: It consists of the following steps: (1) Add ethylene glycol to the PEDOT:PSS solution and mix it with the aqueous polyurethane, and stir vigorously to mix them evenly; (2) adding the MXene solution to the mixed solution obtained in step (1), and mixing them uniformly by vigorous stirring; (3) adding the fructose solution to the mixed solution obtained in step (2), and mixing them evenly by vigorous stirring; (4) The mixed solution obtained in step (3) is heated statically, and a low-impedance electrode material is obtained after the water is completely evaporated.

4. The method according to claim 3, characterized in that The stirring temperature in the steps (1) to (3) is 10 to 30° C., the stirring speed is 100 to 800 rpm, and the heating temperature in the step (4) is 40 to 90° C.

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