Antibacterial operation towel for surgical operation and preparation method thereof

Abstract

The invention relates to the technical field of preparation of medical instruments and new materials, and discloses an antibacterial surgical towel for surgical operation and a preparation method thereof.The antibacterial surgical towel comprises a vapor-permeable film layer, an adhesive layer with iodine and a release layer, the adhesive layer is arranged on the release layer, the vapor-permeable film layer covers the adhesive layer, and the release layer is arranged on the adhesive layer. The adhesive layer is prepared from povidone iodine and solvent type acrylate. Through mutual cooperation of the vapor permeable film layer, the adhesive layer with iodine and the release layer, the surgical towel can effectively isolate external pollutants, can provide a long-acting antibacterial effect through continuous release of free iodine by povidone iodine, and has a good application prospect in practical application. The doctor may adhere the surgical towel around the surgical area before the surgery begins to create a sterile operating area.

Description

Technical Field

[0001] The present disclosure relates to the technical field of medical devices and new material preparation, and in particular, to an antibacterial surgical towel used in surgical operations and a preparation method thereof. Background Art

[0002] During surgery, infection at the surgical site is a serious medical problem that may worsen the patient's condition or even lead to death. Surgical Site Infection (SSI) involves wound and tissue infection during surgery, within thirty days after surgery, or within one year after implant surgery. The source of infection mainly comes from the bacterial flora on the patient's skin. During surgery, common situations such as tissue blood loss and invitamin D, skin incision, and removal of hollow organs often cause the skin around the incision to be contaminated by bacterial flora. Especially for surgeries that require a long operating time, residual bacterial colonies on the skin after disinfection may grow, leading to endogenous surgical site infection.

[0003] In order to cope with and control these infection risks, the current routine practice is to prepare the skin before surgery and disinfect the surgical site in advance. However, due to the biological characteristics of human skin, conventional skin preparation usually cannot achieve a sufficient sterile state. In addition, the disinfectants used for skin preparation are easily soluble in water, so they cannot effectively resist the immersion and flushing of blood, exudate and flushing fluid during surgery, and cannot inhibit the invasion and reproduction of deep endogenous bacteria in the skin. Therefore, even if the skin is disinfected before surgery, the bacteria adhering to the skin in the surgical area will continue to grow, some resident bacteria will remain and reproduce again, and migrate to the surgical site as the operation proceeds. In addition, endogenous bacteria continue to contaminate the surgical area, endangering the health of the patient.

[0004] In response to the above problems, antibacterial surgical films came into being. This type of film is a flexible film product with an antibacterial coating that can be easily adhered to the skin surface where surgery is required. The antibacterial coating provides a sterile surface, inhibits the regeneration of skin bacteria in the surgical area, and fixes and prevents bacterial migration, thereby sealing the skin microenvironment in the surgical area, fixing microorganisms in the surgical area, and inhibiting their reproduction rate, thereby reducing the risk of surgical site infection.

[0005] However, the antibacterial effect of the existing antibacterial surgical film is not long-lasting and the air permeability is poor. It is necessary to further improve the air permeability and the release time and effect of the antibacterial components. Summary of the invention

[0006] The purpose of the present invention is to provide an antibacterial surgical towel for surgical operation and a preparation method thereof, so as to solve the technical problems existing in the prior art.

[0007] In order to achieve the above-mentioned object, according to one aspect of the present disclosure, an antibacterial surgical towel for use in surgical operations is provided, the antibacterial surgical towel comprising a vapor permeable film layer, an adhesive layer having iodine, and a release layer; The adhesive layer is disposed on the release layer, and the vapor permeable film layer covers the adhesive layer; The adhesive layer is prepared from povidone-iodine and solvent-based acrylate.

[0008] Optionally, the iodine content is 0.5-5% of the dry weight of the adhesive layer.

[0009] Optionally, the iodine content is 1%-3% of the dry weight of the adhesive layer.

[0010] Optionally, the adhesive layer further comprises one or more of elemental iodine, iodine complexes and iodine-containing compounds.

[0011] Optionally, the vapor permeable membrane layer is a polyether polyurethane membrane layer.

[0012] Optionally, the vapor permeable membrane layer is a polyetheramide membrane layer.

[0013] Optionally, the water vapor permeability of the polyether polyurethane film layer is greater than 800 g / (m²·24hr), and the elongation at break of the polyether polyurethane film layer is greater than 500%.

[0014] Optionally, the vapor permeable membrane layer has a thickness of 0.01-0.1 mm.

[0015] According to another aspect of the present disclosure, a method for preparing an antibacterial surgical towel for use in surgical operations is provided, the method comprising the following steps: S1, adding 1-3 g of povidone iodine powder to 4-10 g of ethanol, stirring evenly to prepare a mixed solution 1; S2, adding the prepared mixed solution 1 to 10-30 g of acrylic pressure-sensitive adhesive to prepare the adhesive layer; S3, uniformly coating the adhesive layer on one side of the release layer and drying at 80-150° C. for 5-15 min to obtain a coating layer; S4, pasting the vapor permeable membrane layer to one side of the adhesive layer in the coating layer to obtain a composite membrane layer.

[0016] Optionally, in S3, the coating layer has a grammage of 30-60 gsm.

[0017] Through the above technical scheme, through the cooperation between the vapor permeable membrane layer, the adhesive layer with iodine and the release layer, the surgical towel in the present invention can not only effectively isolate external pollutants, but also provide a long-lasting antibacterial effect by continuously releasing free iodine through povidone-iodine. In actual application, the doctor can adhere the surgical towel around the surgical area before the operation begins to create a sterile operating area.

[0018] Other features and advantages of the present disclosure will be described in detail in the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The accompanying drawings are used to provide a further understanding of the present disclosure and constitute a part of the specification. Together with the following specific embodiments, they are used to explain the present disclosure but do not constitute a limitation of the present disclosure. In the accompanying drawings: Figure 1 is a schematic structural diagram of an antibacterial surgical towel used in surgical operations provided by an exemplary embodiment of the present disclosure; Figure 2 The present invention is a flowchart of a method for preparing an antibacterial surgical towel for use in surgical operations provided by an exemplary embodiment of the present invention.

[0020] Description of Reference Numerals 10. Breathable film layer; 20. Adhesive layer; 30. Release layer. DETAILED DESCRIPTION

[0021] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] like Figure 1 to Figure 2 As shown, the present disclosure provides an antibacterial surgical towel for surgical operations, which includes a vapor permeable film layer 10, an adhesive layer 20 having iodine, and a release layer 30. The adhesive layer 20 is arranged on the release layer 30, and the vapor permeable film layer 10 covers the adhesive layer 20. The adhesive layer 20 is prepared from povidone-iodine and solvent-based acrylate.

[0023] Among them, the vapor permeable membrane layer 10 is the outermost part of the surgical towel (specifically, when the surgical towel is adhered to the patient's skin surface, the vapor permeable membrane layer 10 is the layer away from the patient's skin). The function of the vapor permeable membrane layer 10 is mainly to provide a physical barrier to prevent the penetration of external bacteria and other microorganisms. At the same time, it also has a certain vapor permeability, which helps to keep the surgical area dry and comfortable.

[0024] Among them, the adhesive layer 20 with iodine is located between the breathable film layer 10 and the release layer 30, and is used to directly contact the patient's skin surface. Since the adhesive layer 20 is made of povidone iodine and solvent-based acrylate, on the one hand, the adhesive layer 20 can continuously release free iodine during surgery through povidone iodine (antibacterial component) to form an effective antibacterial protective barrier, thereby reducing the risk of surgical site infection; on the other hand, the adhesive layer 20 improves the fit between the surgical towel and the skin through solvent-based acrylate (adhesive), thereby ensuring that the surgical towel will not move or fall off easily during surgery. In addition, the good stretchability of the breathable film can ensure that the surgical towel maintains good comfort and fit during surgical incision retraction and / or joints.

[0025] The release layer 30 is the last layer of the surgical towel and is removed before use to facilitate the adhesion of the adhesive layer 20 to the patient's skin surface. The release paper is used to protect the adhesive layer 20 before use, prevent the adhesive layer 20 from adhering to other objects, and ensure the cleanliness and hygiene of the surgical towel.

[0026] Through the above technical solution, through the cooperation between the vapor permeable membrane layer 10, the adhesive layer 20 with iodine and the release layer 30, the surgical towel in the present invention can not only effectively isolate external pollutants, but also provide a long-lasting antibacterial effect through the continuous release of free iodine through povidone-iodine. In actual application, the doctor can adhere the surgical towel around the surgical area before the operation begins to create a sterile operating area.

[0027] Optionally, the release layer 30 may be a release paper, such as a silicon-coated glassine release paper, or a release film, such as a silicon-coated PET film, which is not limited in the present disclosure.

[0028] As an embodiment, the content of iodine is 0.5%-5% of the dry weight of the adhesive layer 20 .

[0029] Minimum iodine content (0.5%): Even at the lowest iodine content, povidone-iodine still provides effective antimicrobial protection. This concentration is sufficient to kill most common bacteria, fungi and viruses, ensuring a sterile environment in the surgical field.

[0030] Maximum iodine content (5%): At this point, the iodine content is high enough to provide a stronger antibacterial effect without causing excessive irritation or toxicity to the skin (it should be noted that excessive iodine content may cause adverse reactions such as skin allergies).

[0031] In addition, since the iodine content can affect the adhesion of the adhesive layer 20, an appropriate amount of iodine can enhance the adhesion of the adhesive layer 20, making it more stable during surgery and less likely to shift or fall off. Also, since an excessively high iodine content can harden the adhesive layer 20 and reduce the ductility and flexibility of the adhesive layer 20, an appropriate amount of iodine can maintain the good ductility and flexibility of the adhesive layer 20, allowing it to better adapt to the skin curvature of different parts. In some examples, the surgical towel can fit the parts with larger curvatures, such as joints, to provide better protection and comfort.

[0032] That is to say, the setting of this ratio can not only ensure that the adhesive layer 20 can provide continuous and effective antibacterial protection during the operation, but also maintain good adhesion and ensure that the adhesive layer 20 is skin-friendly, thereby reducing allergic reactions.

[0033] Preferably, the iodine content is 1%-3% of the dry weight of the adhesive layer 20. In this way, a balance can be found between antibacterial effect and skin safety. Within the range of 1%-3%, the iodine content in the adhesive layer 20 can provide sufficient antibacterial protection while reducing the risk of irritation or adverse reactions to the skin. In other words, under the premise of ensuring effectiveness, a lower iodine concentration may help reduce costs while reducing unnecessary waste of resources.

[0034] It is important to understand that different forms of iodine can work synergistically to enhance the overall antimicrobial effect. For example, elemental iodine is pure iodine, which has a stronger bactericidal ability and can quickly kill surface bacteria. Iodine complexes (such as polyvinyl alcohol-iodine complexes) can increase the solubility of iodine and regulate the release rate. Iodides (such as sodium iodide (NaI)) can provide an additional iodine source to enhance the antimicrobial effect. Povidone-iodine can provide continuous antimicrobial protection.

[0035] As a first embodiment, the adhesive layer 20 may further include elemental iodine, so that the sterilization effect of the adhesive layer 20 can be enhanced.

[0036] As a second embodiment, the adhesive layer 20 may also include a complex of iodine, so that the solubility of iodine can be increased and the release rate can be adjusted to extend the release time of iodine and ensure that antibacterial protection is continuously provided during the entire surgical procedure.

[0037] As a third embodiment, the adhesive layer 20 may further include iodide, so as to provide an additional iodine source and enhance the antibacterial effect.

[0038] As a fourth embodiment, the adhesive layer 20 may also include elemental iodine and a composite of iodine, which can not only enhance the sterilization effect but also prolong the release time of iodine.

[0039] With respect to the above four implementation methods, the addition amount of elemental iodine and iodide can be adjusted according to specific needs and controlled within a reasonable range to ensure safety and effectiveness.

[0040] As an implementation manner, the vapor permeable membrane layer 10 may be a polyether polyurethane membrane layer.

[0041] The polyether polyurethane film layer is a polyurethane polymer material with a high water vapor permeability, which can effectively discharge moisture from the skin surface and keep the surgical area dry. In addition, the polyether polyurethane film layer has good flexibility and ductility, and can be used in areas with large curvature (such as joints), providing good comfort and stability. In addition, polyether polyurethane has good biocompatibility, is skin-friendly, and will not cause allergic reactions.

[0042] That is, the polyether polyurethane film layer can be used for surgeries that require a long operation time, because its high air permeability and flexibility can ensure long-term comfort and sterile environment. In addition, the polyether polyurethane film layer can be used for complex surgeries involving multiple steps and multiple operations, ensuring that the surgical film can remain stable under various conditions.

[0043] As another embodiment, the vapor permeable membrane layer 10 may be a polyetheramide membrane layer.

[0044] The polyetheramide film layer belongs to the polyetheramide polymer material. It has high water vapor permeability, high mechanical strength and chemical resistance, and can withstand greater physical stress and chemical erosion during surgery. In addition, the polyetheramide film layer can still maintain its performance at high temperatures and can be used in surgical environments that require high-temperature disinfection. In addition, the polyetheramide film layer has excellent wear resistance and tear resistance, which can prevent the surgical film from being damaged during use.

[0045] That is, the polyetheramide film layer can be suitable for surgeries that require high mechanical strength and chemical resistance, such as orthopedic surgery or surgery involving a large number of instrument operations. In addition, the polyetheramide film layer can be used in surgical environments that require high-temperature sterilization to ensure that the surgical film will not be damaged during the sterilization process.

[0046] It should be noted that the polyetheramide film layer can also be adhered to areas with larger curvatures to provide better protection and comfort. In addition, the polyetheramide film layer also has good biocompatibility, is skin-friendly, and will not cause allergic reactions.

[0047] Optionally, the water vapor permeability of the polyether polyurethane film layer is greater than 800 g / (m²·24hr), and the elongation at break of the polyether polyurethane film layer is greater than 500%.

[0048] The polyether polyurethane film layer has high water vapor permeability and good flexibility and ductility.

[0049] A high water vapor transmission rate means that the film can keep the surgical area dry and can effectively remove moisture from the skin surface, reducing the possibility of bacterial growth. At the same time, high vapor permeability can improve patient comfort and reduce discomfort caused by moisture accumulation.

[0050] High elongation at break indicates that the film has excellent flexibility and ductility, and can be used in areas with large curvature (such as joints), providing good comfort and stability. In addition, high ductility enables the film to adapt to various deformations that may occur during surgery, ensuring its stability and reliability during surgery.

[0051] Optionally, the vapor permeable membrane layer 10 has a thickness of 0.01-0.1 mm.

[0052] The thickness of the vapor permeable film layer 10 is 0.01 mm, which has better air permeability and helps to keep the skin around the wound dry. As the thickness of the film layer increases to 0.1 mm, its physical strength and barrier function will also be enhanced accordingly, and it can better resist external pollutants and mechanical damage. Therefore, choosing a vapor permeable film layer 10 thickness of 0.01-0.1 mm is a preferred solution after balancing multiple factors. In actual application, it can be further optimized according to actual needs and intended use.

[0053] like Figure 2 According to another aspect of the present disclosure, a method for preparing an antibacterial surgical towel for surgical operation is provided, and the preparation method comprises the following steps: S1, adding 1-3 g of povidone iodine powder to 4-10 g of ethanol, stirring evenly to prepare a mixed solution 1; S2, adding the prepared mixed solution 1 to 10-30 g of acrylic pressure-sensitive adhesive to prepare an adhesive layer 20; S3, uniformly coating the adhesive layer 20 on one side of the release layer 30 and drying at 80-150° C. for 5-15 min to obtain a coating layer; S4, pasting the vapor permeable membrane layer 10 on one side of the adhesive layer 20 in the coating layer to obtain a composite membrane layer.

[0054] Optionally, in S3, the coating layer has a grammage of 30-60 gsm.

[0055] Example 1 S1, adding 2 g of povidone iodine powder to 6 g of ethanol, stirring evenly to prepare a mixed solution 1; S2, adding the prepared mixed solution 1 to 18 g of a solvent-based acrylic pressure-sensitive adhesive having a solid content of 45%, and mixing them evenly to prepare an adhesive layer 20 (iodine-containing adhesive); S3, coating the adhesive layer 20 evenly on the release surface layer of 60g white glassine release paper and drying at 120°C for 10min to obtain a coating layer with a weight of 47gsm; S4, pasting the polyether polyurethane film layer on one side of the adhesive layer 20 in the coating layer to obtain a composite film layer, wherein the polyether polyurethane film layer has a thickness of 25 microns, a water vapor permeability of 1500 g / (m²·24hr), and a tensile elongation at break of 550%.

[0056] The products formed by the above embodiments and comparative examples (including comparative example 1 3M 6640 antibacterial surgical film and comparative example 2 Zhende antibacterial surgical film) were tested, and the products formed by the above embodiments and comparative examples were tested for their adhesion, peel strength, water barrier, water vapor transmission rate according to YY 0852-2023, and elongation at break according to ASTM D882. The specific test results are shown in Table 1.

[0057] Table 1 Stickiness Peel strength (N / inch) Water barrier Water vapor transmission rate (g / (m²·24hr)) Elongation at break (%) Example No slip 15 No water seepage 800 580 Comparative Example 1 No slip 17 No water seepage 500 670 Comparative Example 2 No slip 5.5 No water seepage 40 430 From the test results of the embodiment and the two comparative examples in Table 1 above, it can be seen that the difference between comparative example 1 (3M 6640 antibacterial surgical film) and the embodiment is that the peel strength of comparative example 1 is slightly higher than that of the embodiment, the water vapor permeability of comparative example 1 is lower than that of the embodiment, and the elongation at break of comparative example 1 is slightly higher than that of the embodiment. That is to say, compared with comparative example 1, the embodiment can more effectively discharge moisture from the skin surface, reduce the risk of bacterial growth, and improve the comfort of the patient.

[0058] The difference between Comparative Example 2 (Zhende Antibacterial Surgical Film) and the Example is that the peel strength of Comparative Example 2 is lower than that of the Example, the water vapor permeability of Comparative Example 2 is lower than that of the Example, and the elongation at break of Comparative Example 2 is lower than that of the Example. That is to say, compared with Comparative Example 2, the Example is less likely to fall off during surgery and can provide higher stability. In addition, the Example can more effectively discharge moisture from the skin surface, reduce the risk of bacterial growth, and improve the comfort of patients.

[0059] In summary, in terms of adhesion retention and water barrier properties, the surgical towel in the present disclosure performs comparable to the comparative example, but is significantly superior to the comparative example in key performance indicators (such as water vapor permeability).

[0060] From the above description, it can be seen that the above embodiments of the present disclosure achieve the following technical effects: 1) The surgical towel disclosed in the present invention has a higher peel strength, which can ensure that the surgical membrane is more stable during the operation and is not easy to fall off.

[0061] 2) The surgical towel disclosed in the present invention has a higher water vapor permeability, which can ensure the dryness of the surgical area, reduce the risk of bacterial growth, and improve the comfort of the patient.

[0062] The preferred embodiments of the present disclosure are described in detail above in conjunction with the accompanying drawings; however, the present disclosure is not limited to the specific details in the above embodiments. Within the technical concept of the present disclosure, a variety of simple modifications can be made to the technical solution of the present disclosure, and these simple modifications all fall within the protection scope of the present disclosure.

[0063] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present disclosure will not further describe various possible combinations.

[0064] In addition, various embodiments of the present disclosure may be arbitrarily combined, and as long as they do not violate the concept of the present disclosure, they should also be regarded as the contents disclosed by the present disclosure.

Claims

1. An antibacterial surgical towel for surgical operation, characterized in that: The antibacterial surgical towel comprises a vapor permeable film layer (10), an adhesive layer (20) containing iodine, and a release layer (30); The adhesive layer (20) is provided on the release layer (30), and the vapor permeable film layer (10) covers the adhesive layer (20); The adhesive layer (20) is prepared from povidone-iodine and solvent-based acrylate.

2. The antibacterial surgical towel according to claim 1, characterized in that: The iodine content is 0.5%-5% of the dry weight of the adhesive layer (20).

3. The antibacterial surgical towel according to claim 2, characterized in that: The iodine content is 1%-3% of the dry weight of the adhesive layer (20).

4. The antibacterial surgical towel according to claim 1, characterized in that: The adhesive layer (20) further comprises one or more of elemental iodine, iodine complexes and iodine-containing compounds.

5. The antibacterial surgical towel according to claim 1, characterized in that: The vapor permeable membrane layer (10) is a polyether polyurethane membrane layer.

6. The antibacterial surgical towel according to claim 1, characterized in that: The vapor permeable membrane layer (10) is a polyetheramide membrane layer.

7. The antibacterial surgical towel according to claim 5, characterized in that: The water vapor permeability of the polyether polyurethane film layer is greater than 800 g / (m²·24hr), and the elongation at break of the polyether polyurethane film layer is greater than 500%.

8. The antibacterial surgical towel according to claim 1, characterized in that: The vapor permeable membrane layer (10) has a thickness of 0.01-0.1 mm.

9. A method for preparing an antibacterial surgical towel for use in surgical operations according to any one of claims 1 to 8, characterized in that: The preparation method comprises the following steps: S1, adding 1-3 g of povidone iodine powder to 4-10 g of ethanol, stirring evenly to prepare a mixed solution 1; S2, adding the prepared mixed solution 1 to 10-30 g of acrylic pressure-sensitive adhesive to prepare the adhesive layer (20); S3, uniformly coating the adhesive layer (20) on one side of the release layer (30) and drying at 80-150° C. for 5-15 minutes to obtain a coating layer; S4, adhering the vapor permeable membrane layer (10) to one side of the adhesive layer (20) in the coating layer to obtain a composite membrane layer.

10. The method for preparing an antibacterial surgical towel for surgical operation according to claim 9, characterized in that: In S3, the coating layer has a grammage of 30-60 gsm.

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