Radiofrequency ablation effect evaluation method and device, equipment and storage medium

Abstract

The invention relates to a radiofrequency ablation effect evaluation method and device, equipment and a storage medium. The method comprises the steps that in the radiofrequency ablation process of a first ablation point, a blood pressure signal of a target object is obtained, and radiofrequency ablation is used for ablating nerve fibers around the first ablation point; according to the blood pressure signal of the target object, a blood pressure fluctuation curve of the first ablation point in the radiofrequency ablation process is determined; determining a blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure fluctuation curve of the first ablation point in the radiofrequency ablation process; and determining the radiofrequency ablation effect of the first ablation point according to the blood pressure reaction type corresponding to the radiofrequency ablation process of the first ablation point. By adopting the method, the intraoperative immediate evaluation of the radiofrequency ablation effect can be realized.

Description

Technical Field

[0001] The present application relates to the field of medical device technology, and in particular to a method, device, equipment and storage medium for evaluating the effect of radiofrequency ablation. Background Art

[0002] Overactive nerves can have adverse effects on human organs or tissues, leading to a series of cardiovascular diseases. For example, chronic overactivation of the sympathetic nerves can cause excessive secretion of renin, increased sodium ion reabsorption by the kidneys, and increased cardiac output, which ultimately leads to increased pulmonary artery blood pressure. Therefore, if overactive nerves are not controlled, it will eventually lead to high-risk cardiovascular events such as heart failure.

[0003] In the related technology, renal sympathetic denervation (RDN) surgery is usually used to treat pulmonary hypertension by performing radiofrequency ablation on the pulmonary artery through a radiofrequency ablation catheter. This surgery can block the autonomic nervous system around the pulmonary artery through radiofrequency heating, reduce the sympathetic nerve tension, and thus achieve a long-term therapeutic effect of reducing pulmonary artery blood pressure.

[0004] However, radiofrequency ablation of the pulmonary artery using a radiofrequency ablation catheter requires long-term follow-up after the RDN surgery to determine the therapeutic effect of the RDN surgery. Currently, it is not possible to conduct immediate evaluation of the effect of radiofrequency ablation during RDN surgery. Summary of the invention

[0005] Based on this, it is necessary to provide a method, device, equipment and storage medium for evaluating the effect of radiofrequency ablation that can instantly evaluate the effect of radiofrequency ablation in order to address the above technical problems.

[0006] In a first aspect, the present application provides a method for evaluating the effect of radiofrequency ablation. The method comprises:

[0007] During radiofrequency ablation of a first ablation point, a blood pressure signal of the target object is acquired, wherein the radiofrequency ablation is used to ablate nerve fibers around the first ablation point;

[0008] determining, according to the blood pressure signal of the target object, a blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point;

[0009] The radiofrequency ablation effect of the first ablation point is determined according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0010] In one embodiment, determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure signal of the target object includes:

[0011] determining a blood pressure fluctuation curve during radiofrequency ablation of the first ablation point according to the blood pressure signal of the target object;

[0012] The blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined according to the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point.

[0013] In one embodiment, determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point includes:

[0014] Obtaining blood pressure values ​​corresponding to multiple time points in the blood pressure fluctuation curve;

[0015] Determining a blood pressure change trend of the blood pressure fluctuation curve according to a change trend between the blood pressure values ​​corresponding to the multiple time points;

[0016] The blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined according to the blood pressure change trend of the blood pressure fluctuation curve.

[0017] In one embodiment, determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure change trend of the blood pressure fluctuation curve includes:

[0018] Obtaining a blood pressure baseline corresponding to the blood pressure fluctuation curve;

[0019] The blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined according to the blood pressure change trend corresponding to the radiofrequency ablation process of the first ablation point and the blood pressure baseline.

[0020] In one embodiment, determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure change trend corresponding to the radiofrequency ablation process of the first ablation point and the blood pressure baseline includes:

[0021] If the blood pressure fluctuation curve shows a trend of continuous increase, determining that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type;

[0022] If the blood pressure fluctuation curve shows a trend of first rising and then falling and the blood pressure fluctuation curve is higher than the blood pressure baseline, it is determined that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type, and the blood pressure value corresponding to the blood pressure baseline is the blood pressure value at the time of starting radiofrequency ablation;

[0023] If the change trend of the blood pressure fluctuation curve is to continuously fluctuate up and down near the blood pressure baseline, then determining that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the third type;

[0024] If the blood pressure fluctuation curve is still in a continuous downward trend after falling below the blood pressure baseline, it is determined that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the fourth type.

[0025] In one embodiment, determining the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point includes:

[0026] If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type, determining that the radiofrequency ablation of the first ablation point is effective;

[0027] If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, the third type, or the fourth type, it is determined that the radiofrequency ablation of the first ablation point is invalid.

[0028] In one embodiment, determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure fluctuation curve of the radiofrequency ablation process of the first ablation point includes:

[0029] The blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point is input into the classification model, and the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point output by the classification model is obtained; wherein the classification model is generated after training with the blood pressure fluctuation curve marked with a type label.

[0030] In one embodiment, determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure fluctuation curve of the radiofrequency ablation process of the first ablation point includes:

[0031] Acquiring the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point;

[0032] determining a change trend of the pulse rate of the target object during the radiofrequency ablation of the first ablation point according to the swing frequency of the blood pressure fluctuation curve during the radiofrequency ablation of the first ablation point;

[0033] According to a change trend of the pulse rate of the target object during the radiofrequency ablation process at the first ablation point, a blood pressure response type corresponding to the radiofrequency ablation process at the first ablation point is determined.

[0034] In one embodiment, after determining the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the method further includes:

[0035] If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type, then the number of ablation points of the second type of blood pressure response is accumulated;

[0036] The radiofrequency ablation of the target object is stopped according to the number of ablation points with the second type of blood pressure response.

[0037] In one embodiment, stopping the radiofrequency ablation of the target object according to the number of ablation points of the second type of blood pressure response includes:

[0038] If the number of ablation points of the second type of blood pressure response exceeds a number threshold, the radiofrequency ablation of the target object is stopped.

[0039] In one embodiment, after determining the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the method further includes:

[0040] If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, determining a second ablation point according to the position of the first ablation point, the second ablation point being a replacement ablation point for the first ablation point;

[0041] Repeat ablation is performed at the second ablation point.

[0042] In one embodiment, after determining the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the method further includes:

[0043] If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the fourth type, the radiofrequency ablation process of the first ablation point is stopped and the third ablation point to be ablated within a preset distance of the first ablation point is removed.

[0044] In a second aspect, the present application also provides a device for evaluating the effect of radiofrequency ablation. The device comprises:

[0045] an acquisition module, used for acquiring a blood pressure signal of a target object during a radiofrequency ablation process at a first ablation point, wherein the radiofrequency ablation is used for ablating nerve fibers around the first ablation point;

[0046] a determination module, configured to determine, according to the blood pressure signal of the target object, a blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point;

[0047] An evaluation module is used to determine the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0048] In one embodiment, the determination module is specifically used to determine the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point according to the blood pressure signal of the target object; determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point;

[0049] In one of the embodiments, the determination module is specifically used to obtain the blood pressure values ​​corresponding to multiple time points in the blood pressure fluctuation curve; determine the blood pressure change trend of the blood pressure fluctuation curve based on the change trend between the blood pressure values ​​corresponding to the multiple time points; determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point based on the blood pressure change trend of the blood pressure fluctuation curve.

[0050] In one embodiment, the determination module is specifically used to obtain a blood pressure baseline corresponding to the blood pressure fluctuation curve; and determine a blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point based on the blood pressure change trend corresponding to the radiofrequency ablation process of the first ablation point and the blood pressure baseline.

[0051] In one embodiment, the determination module is specifically used to determine that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type if the blood pressure fluctuation curve shows a trend of continuous increase; if the blood pressure fluctuation curve shows a trend of first increase and then decrease and the blood pressure fluctuation curves are higher than the blood pressure baseline, then the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined to be the second type, and the blood pressure value corresponding to the blood pressure baseline is the blood pressure value at the time point when radiofrequency ablation is started; if the change trend of the blood pressure fluctuation curve is to continuously fluctuate up and down near the blood pressure baseline, then the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined to be the third type; if the blood pressure fluctuation curve is still in a continuous downward trend after being lower than the blood pressure baseline, then the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined to be the fourth type.

[0052] In one embodiment, the evaluation module is specifically used to determine that the radiofrequency ablation of the first ablation point is effective if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type; if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, the third type or the fourth type, then determine that the radiofrequency ablation of the first ablation point is invalid.

[0053] In one embodiment, the determination module is specifically used to input the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point into a classification model, and obtain the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point output by the classification model; wherein the classification model is generated by training the blood pressure fluctuation curve marked with a type label.

[0054] In one embodiment, the determination module is specifically used to obtain the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation of the first ablation point; determine the pulse rate change trend of the target object during the radiofrequency ablation of the first ablation point according to the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation of the first ablation point; determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the pulse rate change trend of the target object during the radiofrequency ablation of the first ablation point.

[0055] In one embodiment, the device further comprises:

[0056] A processing module is used to accumulate the number of ablation points of the second type of blood pressure response if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type; and stop the radiofrequency ablation of the target object according to the number of ablation points of the second type of blood pressure response.

[0057] In one of the embodiments, the processing unit is specifically configured to stop the radiofrequency ablation of the target object if the number of ablation points of the second type of blood pressure response exceeds a number threshold.

[0058] In one embodiment, the processing unit is further used to determine a second ablation point according to the position of the first ablation point if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, and the second ablation point is an alternative ablation point of the first ablation point; and repeat ablation at the second ablation point.

[0059] In one embodiment, the processing unit is further used to stop the radiofrequency ablation process of the first ablation point and remove the third ablation point to be ablated within a preset distance of the first ablation point if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the fourth type.

[0060] In a third aspect, the present application further provides a computer device, wherein the computer device comprises a memory and a processor, wherein the memory stores a computer program, and the processor executes the radiofrequency ablation effect evaluation method of the first aspect.

[0061] In a fourth aspect, the present application further provides a computer-readable storage medium having a computer program stored thereon, and the computer program is executed by a processor to implement the radiofrequency ablation effect evaluation method of the first aspect.

[0062] In a fifth aspect, the present application further provides a computer program product, which includes a computer program, and when the computer program is executed by a processor, the method for evaluating the effect of radiofrequency ablation according to the first aspect is implemented.

[0063] The above-mentioned radiofrequency ablation effect evaluation method, device, equipment and storage medium first obtain the blood pressure signal of the target object during the radiofrequency ablation process of the first ablation point, and the radiofrequency ablation is used to ablate the nerve fibers around the first ablation point. Secondly, according to the blood pressure signal of the target object, the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point is determined. Thirdly, according to the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point, the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined. Finally, according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the radiofrequency ablation effect of the first ablation point is determined. Since the blood pressure signal of the target object is collected in real time during the operation to determine the blood pressure fluctuation curve, and the blood pressure response type corresponding to the radiofrequency ablation process is determined according to the blood pressure fluctuation curve, the radiofrequency ablation effect is evaluated based on the blood pressure response type, thereby achieving instant evaluation of the radiofrequency ablation effect during the operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0064] Figure 1 A diagram of the application environment of a method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application;

[0065] Figure 2 A schematic diagram of the structure of a device component provided in an embodiment of the present application;

[0066] Figure 3 A schematic diagram of a flow chart of a method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application;

[0067] Figure 4 A schematic diagram of a blood pressure fluctuation curve provided in an embodiment of the present application;

[0068] Figure 5 A schematic diagram of another blood pressure fluctuation curve provided in an embodiment of the present application;

[0069] Figure 6 A schematic diagram of another blood pressure fluctuation curve provided in an embodiment of the present application;

[0070] Figure 7 A schematic diagram of another blood pressure fluctuation curve provided in an embodiment of the present application;

[0071] Figure 8 A schematic diagram of another blood pressure fluctuation curve provided in an embodiment of the present application;

[0072] Fig. 9 A schematic diagram of a pulse rate curve provided in an embodiment of the present application;

[0073] Fig.10 A schematic diagram of an interface in an RDN surgery provided in an embodiment of the present application;

[0074] Fig.11 A schematic flow chart of another method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application;

[0075] Fig.12 A schematic diagram of a flow chart of another method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application;

[0076] Fig.13 A schematic diagram of a flow chart of another method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application;

[0077] Fig.14 A schematic diagram of a flow chart of another method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application;

[0078] Fig.15 A structural block diagram of a radiofrequency ablation effect evaluation device provided in an embodiment of the present application;

[0079] Fig.16 An internal structure diagram of a computer device provided in an embodiment of the present application. DETAILED DESCRIPTION

[0080] In order to make the purpose, technical solution and advantages of the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0081] The radiofrequency ablation effect evaluation method provided in the embodiment of the present application can be applied to Figure 1In the application environment shown. Among them, the device component 101 is connected to the catheter component 102 and the physiological parameter detection component 103 respectively, and the catheter component 102 and the physiological parameter detection component 103 are connected to the human body respectively. When performing RDN surgery, the device component 101 outputs ablation energy to the human body through the catheter component 102, and the catheter component 102 enters the body through unilateral femoral artery puncture to transmit radiofrequency energy to the renal artery intima to ablate the sympathetic nerve fibers around the set ablation point. The physiological parameter detection component 103 can collect the blood pressure signal of the human body during RDN surgery and send the blood pressure signal to the device component 101 in the form of an electrical signal. The device component 101 can determine the blood pressure fluctuation curve during the radiofrequency ablation process of the set ablation point according to the blood pressure signal of the human body, and thus determine the blood pressure response type corresponding to the radiofrequency ablation process of the set ablation point according to the blood pressure fluctuation curve. Finally, the device component 101 determines the radiofrequency ablation effect of the set ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the set ablation point, thereby assisting the doctor in determining whether the nerve fibers at the ablation point have been completely ablated.

[0082] The physiological parameter detection component 103 may include an invasive blood pressure sensor, and accordingly, the blood pressure signal collected by the physiological parameter detection component 103 may be an invasive blood pressure (IBP) signal. Exemplarily, one end of the invasive blood pressure sensor may be connected to a puncture sheath to read the invasive blood pressure, and one end of the invasive blood pressure sensor may be connected to the device component 101 to feed back the invasive blood pressure to the device component 101 in the form of an electrical signal. The puncture sheath connected to the invasive blood pressure sensor and the catheter component 102 enter the human body through the femoral arteries on both sides, respectively, to prevent the movement of the puncture sheath caused by the operation of the catheter component 102 from affecting the blood pressure reading of the invasive blood pressure sensor.

[0083] In some embodiments, when the catheter component 102 outputs ablation energy to the human body, it can also convert the impedance and temperature changes in the area where the ablation point is located into electrical signals, and send them to the device component 101 along the original path, so that the device component 101 can display information such as impedance and temperature changes for the doctor's reference to ensure safety during the treatment process.

[0084] For example, Figure 2As shown, the device component 101 may include a processing module 1011, a waveform detection module 1012, a validity judgment module 1013, a signal transmission module 1014, a driving module 1015 and a collection module 1016. Among them, the catheter component 102 is connected to the driving module 1015 and the collection module 1016 respectively. Under the control of the processing module 1011, the driving module 1015 outputs ablation energy to the human body through the catheter component 102. When the catheter component 102 outputs ablation energy to the human body, the impedance, temperature change and other information of the area where the ablation point is located are collected, and then received by the collection module 1016.

[0085] The signal transmission module 1014 can receive external input signals or output signals to the outside. For example, when radiofrequency ablation is required for a certain ablation point, the doctor can input a trigger signal to the signal transmission module 1014 by means of a key switch, a foot switch, etc. Subsequently, the signal transmission module 1014 sends the trigger signal to the processing module 1011, so that the processing module 1011 triggers the ablation instruction based on the trigger signal. The processing module 1011 can send the ablation instruction to the driving module 1015, so as to drive the driving module 1015 to output ablation energy.

[0086] Correspondingly, the blood pressure signal of the human body during RDN surgery collected by the physiological parameter detection component 103 can also be sent to the processing module 1014. Subsequently, the processing module 1014 can send the blood pressure signal to an external display device through the transmission module 1014, so as to display the blood pressure signal fluctuation of the human body in real time. At the same time, the processing module 1014 can also send the blood pressure signal to the waveform detection module 1012, so that the waveform detection module 1012 generates a blood pressure fluctuation curve according to the blood pressure signal and obtains the key features in the blood pressure fluctuation curve. Finally, the waveform detection module 1012 sends the blood pressure fluctuation curve and the curve features in the blood pressure fluctuation curve to the effectiveness judgment module 1013, and the effectiveness judgment module 1013 determines the blood pressure response type corresponding to the blood pressure fluctuation curve, and then determines the radiofrequency ablation effect.

[0087] In some embodiments, the radiofrequency ablation effect determined by the effectiveness judgment module 1013 and the blood pressure fluctuation curve generated by the waveform detection module 1012 can also be sent to an external display device through the transmission module 1014 for real-time display.

[0088] In one embodiment, Figure 3 As shown, a method for evaluating the effect of radiofrequency ablation is provided. Figure 1 The following is an example of the device components in Figure 1, including S201-S204:

[0089] S201. During radiofrequency ablation at a first ablation point, a blood pressure signal of a target object is obtained.

[0090] In this application, when performing RDN surgery, multiple ablation points need to be subjected to radiofrequency ablation in sequence to remove nerve fibers around the multiple ablation points. During the radiofrequency ablation process at each ablation point, the blood pressure signal of the target object can be obtained in real time, thereby instantly evaluating the radiofrequency ablation effect of the ablation point.

[0091] It should be understood that radiofrequency ablation is used to ablate nerve fibers around the first ablation point. The nerve fibers may be sympathetic nerve fibers. In the present application, by radiofrequency ablation of the sympathetic nerve fibers around the renal artery, the sympathetic nerve tension around the kidney can be reduced, thereby increasing the glomerular filtration rate, reducing the reabsorption capacity of the kidney, and reducing the reabsorption of sodium ions and water, thereby achieving a decrease in blood pressure.

[0092] It should be understood that the above blood pressure signal may include diastolic pressure, systolic pressure, average blood pressure, etc. The average blood pressure may be the average value of the diastolic pressure and the systolic pressure corresponding to each time point or each fluctuation.

[0093] The target object may be a patient undergoing RDN surgery, and the first ablation point may be any ablation point in the RDN surgery.

[0094] It should be understood that the embodiments of the present application do not limit how to obtain the blood pressure signal of the target object. In some embodiments, the device component can collect the blood pressure signal of the target object through a physiological parameter detection component. Exemplarily, the physiological parameter detection component can collect the blood pressure signal of the target object in real time according to the collection frequency during RDN surgery. Alternatively, after the device component receives the ablation instruction, the device component can also instruct the physiological parameter detection component to start collecting the blood pressure signal of the target object. Among them, the above-mentioned collection frequency can be specifically set according to actual conditions, for example, 300 Hz, 200 Hz, etc. The above-mentioned physiological parameter detection component can be an invasive blood pressure sensor, and accordingly, the above-mentioned blood pressure signal can be an invasive blood pressure signal.

[0095] S202: Determine, according to the blood pressure signal of the target object, a blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0096] Determine the blood pressure fluctuation curve during radiofrequency ablation of the first ablation point.

[0097] In this step, after the device component obtains the blood pressure signal of the target object during the radiofrequency ablation process at the first ablation point, the blood pressure response type corresponding to the radiofrequency ablation process at the first ablation point can be determined.

[0098] It should be understood that the embodiments of the present application do not limit how to determine the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point according to the blood pressure signal of the target object. In some embodiments, the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point can be determined according to the blood pressure signal of the target object. Subsequently, the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined according to the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point.

[0099] In some embodiments, since the physiological parameter detection component collects the blood pressure signal of the target object according to the collection frequency, the device component can use linear interpolation to differentiate the blood pressure signals collected at two collection points to supplement the blood pressure information between the two collection points, thereby drawing a continuous blood pressure fluctuation curve.

[0100] In some embodiments, the blood pressure fluctuation curve may include not only the blood pressure signal of the target object during the radiofrequency ablation of the first ablation point, but also the blood pressure signal of the target object within a preset time before the radiofrequency ablation of the first ablation point. The preset time may be specifically set according to actual conditions, such as 5 seconds, 10 seconds, etc.

[0101] It should be noted that the above-mentioned blood pressure fluctuation curve may include multiple time points, and the blood pressure signal corresponding to each time point is a fluctuation of the blood pressure fluctuation curve. Each fluctuation includes a coordinate point of a blood pressure signal value collected by a collection point or a blood pressure signal value inserted by a difference point. The connecting lines between the coordinate points of the blood pressure signal values ​​corresponding to multiple adjacent time points can constitute a blood pressure fluctuation curve.

[0102] It should be understood that the blood pressure fluctuation curve involved in the embodiment of the present application may include at least one of the following: a diastolic pressure fluctuation curve, a systolic pressure fluctuation curve and a mean blood pressure fluctuation curve.

[0103] In some embodiments, the above-mentioned blood pressure fluctuation curve can be generated by the acquisition module in the device component after receiving the blood pressure signal, or it can be generated by the waveform detection model in the device component. The embodiments of the present application are not limited to this.

[0104] It should be understood that the present embodiment does not limit how to determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point. Exemplarily, the following are three ways of determining the blood pressure response type provided in the present embodiment.

[0105] In one approach, the device component may first obtain blood pressure values ​​corresponding to multiple time points in the blood pressure fluctuation curve. Secondly, the device component may determine the blood pressure change trend of the blood pressure fluctuation curve based on the change trend between the blood pressure values ​​corresponding to the multiple time points. Finally, the device component may determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point based on the blood pressure change trend of the blood pressure fluctuation curve.

[0106] Exemplarily, the change trend between the blood pressure values ​​corresponding to multiple time points can be determined by combining the blood pressure change trends between adjacent time points.

[0107] It should be understood that the blood pressure values ​​corresponding to the above-mentioned multiple time points may be the blood pressure values ​​of the blood pressure signal corresponding to each blood pressure fluctuation. By comparing the blood pressure value of the blood pressure signal at the previous time point with the blood pressure value of the blood pressure signal at the next time point, it is possible to determine whether the blood pressure change trend between the two time points is rising or falling. Subsequently, the blood pressure change trends between all time points are summarized to obtain the blood pressure change trend of the blood pressure fluctuation curve.

[0108] For example, Figure 4-Figure 8 This is a schematic diagram of a blood pressure fluctuation curve provided in an embodiment of the present application. Figure 4-Figure 8 The horizontal axis is the ablation time (s), and the vertical axis is the blood pressure (mmHg). The identification line S is used to identify the blood pressure value of the blood pressure signal collected when the ablation time is 0, that is, the blood pressure value when the radio frequency energy starts to be output.

[0109] In some embodiments, the device component can first obtain a blood pressure baseline corresponding to the blood pressure fluctuation curve, and then determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point based on the blood pressure change trend and the blood pressure baseline corresponding to the radiofrequency ablation process of the first ablation point.

[0110] It should be noted that Figure 4-Figure 6 The diastolic pressure fluctuation curve and the systolic pressure fluctuation curve are included, and both the diastolic pressure fluctuation curve and the systolic pressure fluctuation curve can be used as blood pressure fluctuation curves to determine the blood pressure response type. Figure 4-Figure 6 The systolic blood pressure fluctuation curve in is used as the blood pressure fluctuation curve to illustrate the determination process of each blood pressure response type.

[0111] For example, Figure 4 As shown, if the blood pressure value corresponding to the previous time point in the blood pressure fluctuation curve is always smaller than the blood pressure value corresponding to the later time point, it is determined that the blood pressure fluctuation curve has a continuously increasing trend. Correspondingly, if the blood pressure fluctuation curve has a continuously increasing trend, it is determined that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type.

[0112] For example, Figure 5As shown, a blood pressure baseline can also be set in the blood pressure fluctuation curve, and the blood pressure value corresponding to the blood pressure baseline is the blood pressure value at the time point when radiofrequency ablation is started. If the blood pressure fluctuation curve includes two bands, the first band is before the second band, and both the first band and the second band are higher than the blood pressure baseline. The blood pressure value corresponding to the previous time point in the first band is always smaller than the blood pressure value corresponding to the next time point, and the blood pressure value corresponding to the previous time point in the first band is always larger than the blood pressure value corresponding to the next time point, then the blood pressure fluctuation curve is determined to have a trend of first rising and then falling. Correspondingly, if the blood pressure fluctuation curve has a trend of first rising and then falling and the blood pressure fluctuation curves are all higher than the blood pressure baseline, then the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined to be the second type.

[0113] For example, Figure 6 As shown in the figure, if the blood pressure values ​​corresponding to each time point are randomly on the upper and lower sides of the blood pressure baseline, the blood pressure fluctuation curve is determined to be a trend of continuous fluctuations near the blood pressure baseline. Correspondingly, if the change trend of the blood pressure fluctuation curve is continuous fluctuations near the blood pressure baseline, the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined to be the third type.

[0114] For example, Figure 7 and Figure 8 The blood pressure fluctuation curve in can be a diastolic pressure fluctuation curve, a systolic pressure fluctuation curve or a mean blood pressure fluctuation curve. Figure 7 and Figure 8 As shown, if the blood pressure fluctuation curve is still in a continuous downward trend after falling below the blood pressure baseline, it is determined that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the fourth type.

[0115] In the second method, the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point can also be input into the classification model, and the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point output by the classification model can be obtained; wherein the classification model is generated after training with the blood pressure fluctuation curve marked with type labels.

[0116] It should be understood that the embodiments of the present application do not limit the classification model, and it can be any suitable artificial intelligence (AI) model.

[0117] Compared with the first method, by using a trained classification model to identify the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the influence of fluctuations caused by abnormal blood pressure signals at individual time points on the corresponding recognition results can be avoided, thereby improving the recognition accuracy.

[0118] In the third mode, the device component may first obtain the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point. Subsequently, the device component may determine the change trend of the pulse rate of the target object during the radiofrequency ablation process of the first ablation point based on the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point. Finally, the device component may determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point based on the change trend of the pulse rate of the target object during the radiofrequency ablation process of the first ablation point.

[0119] The oscillation frequency may be a frequency between two systolic pressures and / or two diastolic pressures. Since pulse rate (PR) is generally used as an important reference index of a patient's heart rate in clinical practice, the type of blood pressure response corresponding to the radiofrequency ablation process may also be determined by the change trend of the pulse rate.

[0120] For example, Fig. 9 A schematic diagram of a pulse rate curve provided in an embodiment of the present application. Fig. 9 The curve T in the figure is the pulse rate of the patient. The type of blood pressure response corresponding to the radiofrequency ablation process can be determined by the rise, fall or unchanged pulse rate, so as to determine whether the ablation has been completed or make a suggestion to stop the ablation immediately.

[0121] S203: Determine the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0122] In this step, after the component device determines the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the radiofrequency ablation effect of the first ablation point can be determined according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0123] In some embodiments, if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type, the radiofrequency ablation of the first ablation point is determined to be effective. If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, the third type, or the fourth type, the radiofrequency ablation of the first ablation point is determined to be ineffective.

[0124] It should be noted that there is a correlation between the number of ablation points of the second type of blood pressure response type and the long-term therapeutic effect of the RDN surgery. That is, the more ablation points of the second type of blood pressure response type there are, the greater the long-term surgical benefit of the patient. Therefore, when performing the RDN surgery, it is possible to ensure that the number of ablation points of the second type of blood pressure response type is as large as possible. At the same time, it is also possible to determine whether to end the radiofrequency ablation of the RDN surgery based on the number of ablation points of the second type of blood pressure response type.

[0125] In some embodiments, if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type, the number of ablation points of the second type of blood pressure response is accumulated. Subsequently, the radiofrequency ablation of the target object is stopped according to the number of ablation points of the second type of blood pressure response.

[0126] For example, if the number of ablation points of the second type of blood pressure response exceeds a quantity threshold, the radiofrequency ablation of the target object is stopped. The quantity threshold can be specifically set according to actual conditions, and the embodiment of the present application does not limit this.

[0127] In addition, different follow-up operations can also be used to improve the therapeutic effect of RDN surgery if radiofrequency ablation of the first ablation point is ineffective due to different types of blood pressure response.

[0128] In some embodiments, if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, the second ablation point is determined according to the position of the first ablation point, and the second ablation point is a replacement ablation point of the first ablation point. Subsequently, ablation can be repeated at the second ablation point.

[0129] It should be understood that for the first type of blood pressure response, repeated ablation can be performed at the ablation point near it to convert it into the second type of blood pressure response. During the repeated ablation, a second ablation point can be determined near the location of the first ablation point by a three-dimensional mapping device and / or a catheter including multiple branches, so that repeated ablation can be performed on the second ablation point.

[0130] In some embodiments, if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the fourth type, the radiofrequency ablation process of the first ablation point is stopped and the third ablation point to be ablated within the preset distance of the first ablation point is removed. The above preset distance can be specifically set according to actual conditions, and the embodiments of the present application are not limited to this.

[0131] It should be understood that the fourth type of ablation point often causes the blood pressure of the treated patient to rise instead of fall. Therefore, the radiofrequency ablation process of the first ablation point needs to be stopped immediately. At the same time, in the subsequent treatment process, the third ablation point around the first ablation point needs to be avoided to avoid the recurrence of the fourth type of ablation point.

[0132] In some embodiments, if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the third type, the radiofrequency ablation process of the first ablation point is stopped and radiofrequency ablation of the next ablation point is performed.

[0133] In some embodiments, during the radiofrequency ablation process at the first ablation point, the acquired blood pressure signal of the target object, the determined blood pressure fluctuation curve and blood pressure response type, etc. may also be sent to an external display device so that the external display device displays the above information.

[0134] For example, Fig.10 This is a schematic diagram of an interface in an RDN operation provided in an embodiment of the present application. Fig.10 The interface includes information such as the blood pressure fluctuation curve 10, the ablation basic parameter curve 29, the blood pressure response type 31, the pulse rate 32 and the ablation progress 30, so that the doctor can view it in real time and grasp the progress of the operation.

[0135] In this application, a surgical circuit system formed by a physiological parameter detection component is set up to collect the target object's blood pressure signal in real time, so as to determine the radiofrequency ablation effect of the ablation point according to the blood pressure signal, so as to correct the subsequent operation in time. At the same time, based on the blood pressure fluctuation curve corresponding to the radiofrequency ablation process of the ablation point, the blood pressure response type corresponding to the radiofrequency ablation process is determined, so as to achieve instant intraoperative evaluation of the radiofrequency ablation effect.

[0136] The method for evaluating the effect of radiofrequency ablation provided in the embodiment of the present application first obtains the blood pressure signal of the target object during the radiofrequency ablation process at the first ablation point, and the radiofrequency ablation is used to ablate the nerve fibers around the first ablation point. Secondly, the blood pressure response type corresponding to the radiofrequency ablation process at the first ablation point is determined based on the blood pressure signal of the target object. Finally, the radiofrequency ablation effect of the first ablation point is determined based on the blood pressure response type corresponding to the radiofrequency ablation process at the first ablation point. Since the blood pressure signal of the target object is collected in real time during the operation to determine the blood pressure fluctuation curve, and the blood pressure response type corresponding to the radiofrequency ablation process is determined based on the blood pressure fluctuation curve, the radiofrequency ablation effect is evaluated based on the blood pressure response type, thereby achieving instant evaluation of the radiofrequency ablation effect during the operation.

[0137] The following specifically describes how to adjust subsequent operations based on the blood pressure response type corresponding to the radiofrequency ablation process. Fig.11 A flow chart of another method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application. Fig.11 As shown, the method for evaluating the effect of radiofrequency ablation includes S301-S312:

[0138] S301, during radiofrequency ablation of a current ablation point, obtaining a blood pressure signal of a target object, wherein radiofrequency ablation is used to ablate nerve fibers around a first ablation point;

[0139] S302, determining a blood pressure fluctuation curve during radiofrequency ablation of a first ablation point according to a blood pressure signal of the target subject;

[0140] S303: Determine whether the blood pressure response type is the second type.

[0141] If yes, execute S304, if no, execute S309.

[0142] S304: Stop the radiofrequency ablation process at the current ablation point.

[0143] S305: Accumulate the number of ablation points of the second type of blood pressure response.

[0144] S306: Determine whether the number of ablation points of the second type of blood pressure response exceeds a number threshold.

[0145] If yes, execute S307, if no, execute S308.

[0146] S307 , stopping radiofrequency ablation of the target object.

[0147] S308. Adjust the position of the catheter according to the planned path.

[0148] After S308, S301 is executed.

[0149] S309: Determine whether the blood pressure response type is the first type.

[0150] If yes, execute S310, if no, execute S304.

[0151] S310: Determine a second ablation point according to the position of the first ablation point, where the second ablation point is a replacement ablation point for the first ablation point.

[0152] S311, performing repeated ablation at the second ablation point.

[0153] S312: Determine whether to change to the second type of blood pressure response type.

[0154] If yes, execute S304, if no, execute S309.

[0155] The following are three ways to determine the blood pressure response type.

[0156] Fig.12 A flowchart of another method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application is shown below. Fig.12 The first method for determining the blood pressure response type is shown above. The method for evaluating the effect of radiofrequency ablation includes S401-S407:

[0157] S401 . During radiofrequency ablation at a first ablation point, a blood pressure signal of a target object is obtained. Radiofrequency ablation is used to ablate nerve fibers around the first ablation point.

[0158] S402: Determine a blood pressure fluctuation curve during radiofrequency ablation of a first ablation point according to a blood pressure signal of the target object.

[0159] S403: Obtain blood pressure values ​​corresponding to multiple time points in the blood pressure fluctuation curve.

[0160] S404: Determine the blood pressure change trend between adjacent time points based on the blood pressure values ​​corresponding to the multiple time points.

[0161] S405: Determine the blood pressure change trend of the blood pressure fluctuation curve according to the blood pressure change trend between adjacent time points.

[0162] S406: Determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure change trend of the blood pressure fluctuation curve.

[0163] S407: Determine the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0164] Fig.13 A flowchart of another method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application is shown below. Fig.13 The second method for determining the blood pressure response type is shown. The method for evaluating the effect of radiofrequency ablation includes S501-S504:

[0165] S501 . During radiofrequency ablation at a first ablation point, a blood pressure signal of a target object is obtained. Radiofrequency ablation is used to ablate nerve fibers around the first ablation point.

[0166] S502: Determine a blood pressure fluctuation curve during radiofrequency ablation of a first ablation point according to a blood pressure signal of the target object.

[0167] S503. Input the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point into the classification model, and obtain the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point output by the classification model; wherein the classification model is generated after training with the blood pressure fluctuation curve marked with a type label.

[0168] S504: Determine the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0169] Fig.14 A flowchart of another method for evaluating the effect of radiofrequency ablation provided in an embodiment of the present application is shown below. Fig.14 The second method for determining the blood pressure response type is shown. The method for evaluating the effect of radiofrequency ablation includes S601-S606:

[0170] S601. During radiofrequency ablation at a first ablation point, a blood pressure signal of a target object is obtained. Radiofrequency ablation is used to ablate nerve fibers around the first ablation point.

[0171] S602: Determine a blood pressure fluctuation curve during radiofrequency ablation of a first ablation point according to a blood pressure signal of the target object.

[0172] S603: Obtain the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point.

[0173] S604: Determine a pulse rate variation trend of the target object during the radiofrequency ablation at the first ablation point according to the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation at the first ablation point.

[0174] S605: Determine the blood pressure response type corresponding to the radiofrequency ablation process at the first ablation point according to the pulse rate change trend of the target object during the radiofrequency ablation process at the first ablation point.

[0175] S606: Determine the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0176] The method for evaluating the effect of radiofrequency ablation provided in the embodiment of the present application first obtains the blood pressure signal of the target object during the radiofrequency ablation process of the first ablation point, and the radiofrequency ablation is used to ablate the nerve fibers around the first ablation point. Secondly, the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point is determined based on the blood pressure signal of the target object. Thirdly, the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined based on the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point. Finally, the radiofrequency ablation effect of the first ablation point is determined based on the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point. Since the blood pressure signal of the target object is collected in real time during the operation to determine the blood pressure fluctuation curve, and the blood pressure response type corresponding to the radiofrequency ablation process is determined based on the blood pressure fluctuation curve, the radiofrequency ablation effect is evaluated based on the blood pressure response type, thereby achieving instant evaluation of the radiofrequency ablation effect during the operation.

[0177] It should be understood that, although the steps in the flowcharts involved in the above embodiments are displayed in sequence according to the indication of the arrows, these steps are not necessarily executed in sequence according to the order indicated by the arrows. Unless there is a clear explanation in this article, the execution of these steps is not strictly limited in order, and these steps can be executed in other orders. Moreover, at least a part of the steps in the flowcharts involved in the above embodiments may include multiple steps or multiple stages, and these steps or stages are not necessarily executed at the same time, but can be executed at different times, and the execution order of these steps or stages is not necessarily carried out in sequence, but can be executed in turn or alternately with other steps or at least a part of the steps or stages in other steps.

[0178] Based on the same inventive concept, the embodiment of the present application also provides a radiofrequency ablation effect evaluation device for implementing the radiofrequency ablation effect evaluation method involved above. The implementation scheme for solving the problem provided by the device is similar to the implementation scheme recorded in the above method, so the specific limitations of one or more radiofrequency ablation effect evaluation device embodiments provided below can refer to the limitations of the radiofrequency ablation effect evaluation method above, and will not be repeated here.

[0179] In one embodiment, Fig.15 As shown, a radiofrequency ablation effect evaluation device 700 is provided, comprising: an acquisition module 701, a determination module 702, an evaluation module 703 and a processing module 704, wherein:

[0180] The acquisition module 701 is used to acquire the blood pressure signal of the target object during the radiofrequency ablation process at the first ablation point, where the radiofrequency ablation is used to ablate the nerve fibers around the first ablation point.

[0181] The determination module 702 is used to determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure signal of the target object.

[0182] The evaluation module 703 is used to determine the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

[0183] In one embodiment, the determination module 702 is specifically used to determine the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point according to the blood pressure signal of the target object; and determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point.

[0184] In one of the embodiments, the determination module 702 is specifically used to obtain the blood pressure values ​​corresponding to multiple time points in the blood pressure fluctuation curve; determine the blood pressure change trend of the blood pressure fluctuation curve based on the change trend between the blood pressure values ​​corresponding to the multiple time points; determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point based on the blood pressure change trend of the blood pressure fluctuation curve.

[0185] In one embodiment, the determination module 702 is specifically used to obtain a blood pressure baseline corresponding to the blood pressure fluctuation curve; and determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure change trend and the blood pressure baseline corresponding to the radiofrequency ablation process of the first ablation point.

[0186] In one embodiment, the determination module 702 is specifically used to determine that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type if the blood pressure fluctuation curve shows a trend of continuous increase; if the blood pressure fluctuation curve shows a trend of first increase and then decrease and the blood pressure fluctuation curves are all higher than the blood pressure baseline, then the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined to be the second type, and the blood pressure value corresponding to the blood pressure baseline is the blood pressure value at the time of starting radiofrequency ablation; if the change trend of the blood pressure fluctuation curve is continuous fluctuations around the blood pressure baseline, then the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined to be the third type; if the blood pressure fluctuation curve is still in a continuous downward trend after being lower than the blood pressure baseline, then the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined to be the fourth type.

[0187] In one embodiment, the evaluation module 703 is specifically used to determine that the radiofrequency ablation of the first ablation point is effective if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type; if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, the third type or the fourth type, then determine that the radiofrequency ablation of the first ablation point is invalid.

[0188] In one embodiment, the determination module 702 is specifically used to input the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point into the classification model, and obtain the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point output by the classification model; wherein the classification model is generated after training with the blood pressure fluctuation curve marked with a type label.

[0189] In one embodiment, the determination module 702 is specifically used to obtain the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point; determine the pulse rate change trend of the target object during the radiofrequency ablation process of the first ablation point according to the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point; determine the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the pulse rate change trend of the target object during the radiofrequency ablation process of the first ablation point.

[0190] In one embodiment, the device further comprises:

[0191] The processing module 704 is used to accumulate the number of ablation points of the second type of blood pressure response if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type; and stop the radiofrequency ablation of the target object according to the number of ablation points of the second type of blood pressure response.

[0192] In one embodiment, the processing module 704 is specifically configured to stop the radiofrequency ablation of the target object if the number of ablation points with the second type of blood pressure response exceeds a number threshold.

[0193] In one of the embodiments, the processing module is further used to determine a second ablation point according to the position of the first ablation point if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, and the second ablation point is a replacement ablation point for the first ablation point; and repeat ablation at the second ablation point.

[0194] In one embodiment, the processing module 704 is further configured to stop the radiofrequency ablation process of the first ablation point and remove a third ablation point to be ablated within a preset distance of the first ablation point if the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the fourth type.

[0195] In the device embodiment, in addition to the embodiment of the device alone, it is also necessary to write out the embodiments of the device items that correspond one-to-one to the method items.

[0196] Each module in the above-mentioned radiofrequency ablation effect evaluation device can be implemented in whole or in part by software, hardware, or a combination thereof. Each of the above-mentioned modules can be embedded in or independent of a processor in a computer device in the form of hardware, or can be stored in a memory in a computer device in the form of software, so that the processor can call and execute the operations corresponding to each of the above modules.

[0197] In one embodiment, a computer device is provided. The computer device may be a terminal, and its internal structure diagram may be as follows: Fig.16As shown. The computer device includes a processor, a memory, an input / output interface, a communication interface, a display unit and an input device. The processor, the memory and the input / output interface are connected via a system bus, and the communication interface, the display unit and the input device are connected to the system bus via the input / output interface. The processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The input / output interface of the computer device is used to exchange information between the processor and an external device. The communication interface of the computer device is used to communicate with an external terminal in a wired or wireless manner, and the wireless manner can be implemented through WIFI, a mobile cellular network, NFC (near field communication) or other technologies. When the computer program is executed by the processor, a method for evaluating the effect of radiofrequency ablation is implemented.

[0198] The display unit of the computer device is used to form a visually visible picture, and can be a display screen, a projection device, or a virtual reality imaging device. The display screen can be a liquid crystal display screen or an electronic ink display screen, and the input device of the computer device can be a touch layer covered on the display screen, or a key, trackball, or touchpad provided on the computer device housing, or an external keyboard, touchpad, or mouse, etc.

[0199] Those skilled in the art will understand that Fig.16 The structure shown in the figure is only a block diagram of a part of the structure related to the solution of the present application, and does not constitute a limitation on the computer device to which the solution of the present application is applied. The specific computer device may include more or fewer components than those shown in the figure, or combine certain components, or have a different arrangement of components.

[0200] In one embodiment, a computer device is provided, including a memory and a processor, wherein a computer program is stored in the memory, and the processor implements the above-mentioned radiofrequency ablation effect evaluation method when executing the computer program.

[0201] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the above-mentioned radiofrequency ablation effect evaluation method is implemented.

[0202] In one embodiment, a computer program product is provided, including a computer program, which implements the above-mentioned radiofrequency ablation effect evaluation method when executed by a processor.

[0203] Those skilled in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to the memory, database or other medium used in the embodiments provided in the present application can include at least one of non-volatile and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetoresistive random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. As an illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM). The database involved in each embodiment provided in this application may include at least one of a relational database and a non-relational database. Non-relational databases may include distributed databases based on blockchains, etc., but are not limited to this. The processor involved in each embodiment provided in this application may be a general-purpose processor, a central processing unit, a graphics processor, a digital signal processor, a programmable logic device, a data processing logic device based on quantum computing, etc., but are not limited to this.

[0204] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0205] The above embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.

Claims

1. A method for evaluating the effect of radiofrequency ablation, characterized in that: The method comprises: During radiofrequency ablation of a first ablation point, a blood pressure signal of the target object is acquired, wherein the radiofrequency ablation is used to ablate nerve fibers around the first ablation point; determining, according to the blood pressure signal of the target object, a blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point; The radiofrequency ablation effect of the first ablation point is determined according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

2. The method according to claim 1, characterized in that The step of determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure signal of the target object includes: determining a blood pressure fluctuation curve during radiofrequency ablation of the first ablation point according to the blood pressure signal of the target object; The blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined according to the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point.

3. The method according to claim 2, characterized in that The determining, according to the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point, the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point includes: Obtaining blood pressure values ​​corresponding to multiple time points in the blood pressure fluctuation curve; Determining a blood pressure change trend of the blood pressure fluctuation curve according to a change trend between the blood pressure values ​​corresponding to the multiple time points; The blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined according to the blood pressure change trend of the blood pressure fluctuation curve.

4. The method according to claim 3, characterized in that The step of determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure change trend of the blood pressure fluctuation curve includes: Obtaining a blood pressure baseline corresponding to the blood pressure fluctuation curve; The blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is determined according to the blood pressure change trend corresponding to the radiofrequency ablation process of the first ablation point and the blood pressure baseline.

5. The method according to claim 4, characterized in that Determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure change trend corresponding to the radiofrequency ablation process of the first ablation point and the blood pressure baseline includes: If the blood pressure fluctuation curve shows a trend of continuous increase, determining that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type; If the blood pressure fluctuation curve shows a trend of first rising and then falling and the blood pressure fluctuation curve is higher than the blood pressure baseline, it is determined that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type, and the blood pressure value corresponding to the blood pressure baseline is the blood pressure value at the time of starting radiofrequency ablation; If the change trend of the blood pressure fluctuation curve is to continuously fluctuate up and down near the blood pressure baseline, then determining that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the third type; If the blood pressure fluctuation curve is still in a continuous downward trend after falling below the blood pressure baseline, it is determined that the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the fourth type.

6. The method according to claim 5, characterized in that The determining the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point includes: If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type, determining that the radiofrequency ablation of the first ablation point is effective; If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, the third type, or the fourth type, it is determined that the radiofrequency ablation of the first ablation point is invalid.

7. The method according to claim 1, characterized in that The step of determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure fluctuation curve of the radiofrequency ablation process of the first ablation point includes: The blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point is input into the classification model, and the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point output by the classification model is obtained; wherein the classification model is generated after training with the blood pressure fluctuation curve marked with a type label.

8. The method according to claim 1, characterized in that The step of determining the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point according to the blood pressure fluctuation curve of the radiofrequency ablation process of the first ablation point includes: Acquiring the oscillation frequency of the blood pressure fluctuation curve during the radiofrequency ablation process of the first ablation point; determining a change trend of the pulse rate of the target object during the radiofrequency ablation of the first ablation point according to the swing frequency of the blood pressure fluctuation curve during the radiofrequency ablation of the first ablation point; According to a change trend of the pulse rate of the target object during the radiofrequency ablation process at the first ablation point, a blood pressure response type corresponding to the radiofrequency ablation process at the first ablation point is determined.

9. The method according to any one of claims 1 to 8, characterized in that: After determining the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the method further includes: If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the second type, then the number of ablation points of the second type of blood pressure response is accumulated; The radiofrequency ablation of the target object is stopped according to the number of ablation points with the second type of blood pressure response.

10. The method according to claim 9, characterized in that The step of stopping the radiofrequency ablation of the target object according to the number of ablation points of the second type of blood pressure response comprises: If the number of ablation points of the second type of blood pressure response exceeds a number threshold, the radiofrequency ablation of the target object is stopped.

11. The method according to any one of claims 1 to 8, characterized in that: After determining the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the method further includes: If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the first type, determining a second ablation point according to the position of the first ablation point, the second ablation point being a replacement ablation point for the first ablation point; Repeat ablation is performed at the second ablation point.

12. The method according to any one of claims 1 to 8, characterized in that: After determining the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point, the method further includes: If the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point is the fourth type, the radiofrequency ablation process of the first ablation point is stopped and the third ablation point to be ablated within a preset distance of the first ablation point is removed.

13. A radiofrequency ablation effect evaluation device, characterized in that: The device comprises: an acquisition module, used for acquiring a blood pressure signal of a target object during a radiofrequency ablation process at a first ablation point, wherein the radiofrequency ablation is used for ablating nerve fibers around the first ablation point; a determination module, configured to determine, according to the blood pressure signal of the target object, a blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point; An evaluation module is used to determine the radiofrequency ablation effect of the first ablation point according to the blood pressure response type corresponding to the radiofrequency ablation process of the first ablation point.

14. A computer device comprising a memory and a processor, wherein the memory stores a computer program, wherein: When the processor executes the computer program, the steps of the method according to any one of claims 1 to 12 are implemented.

15. A computer-readable storage medium having a computer program stored thereon, characterized in that: When the computer program is executed by a processor, the steps of the method according to any one of claims 1 to 12 are implemented.

16. A computer program product comprising a computer program, characterized in that When the computer program is executed by a processor, the steps of the method according to any one of claims 1 to 12 are implemented.

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