Liquor dreg water-soluble glucose oligosaccharide, preparation method and application thereof

By preparing and purifying water-soluble glucose oligosaccharides from strong-aroma baijiu lees, the problem of insufficient research on this topic in existing technologies has been solved, achieving a highly effective relief of alcoholic liver disease and enhancing the utilization value of baijiu lees resources.

CN119529129BActive Publication Date: 2026-06-30LUZHOU LAOJIAO CO LTD +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
LUZHOU LAOJIAO CO LTD
Filing Date
2024-11-25
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

Existing technologies lack in-depth research on water-soluble glucose oligosaccharides in strong-aroma baijiu lees and their application in alleviating alcoholic liver disease, and traditional drugs have the risk of side effects.

Method used

By preparing a water-soluble glucose oligosaccharide from strong-aroma baijiu lees composed of a glucose backbone and arabinose, galactose, glucose, and xylose, the oligosaccharide was extracted and purified by ultrasonic pretreatment, enzymatic hydrolysis, dialysis, and chromatography to obtain an oligosaccharide with a molecular weight of 2800~3000 Da and a purity greater than 83%.

Benefits of technology

This method enables the efficient extraction of high-purity water-soluble glucose oligosaccharides from strong-aroma baijiu lees, significantly alleviating alcoholic liver disease, regulating liver lipid metabolism, repairing liver cell damage, increasing the activity of antioxidant enzymes in liver tissue, and enhancing the resource utilization value of baijiu lees.

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Abstract

The application discloses Luzhou-flavor liquor dreg water-soluble glucose oligosaccharide and a preparation method and application thereof, and belongs to the technical field of medicines.The application extracts water-soluble glucose oligosaccharide from Luzhou-flavor liquor dreg as raw material.The main chain of the Luzhou-flavor liquor dreg water-soluble glucose oligosaccharide is composed of glucose, and the side chain comprises arabinose and glucose; the Luzhou-flavor liquor dreg water-soluble glucose oligosaccharide is composed of arabinose, galactose, glucose and xylose, and the molar ratio is 8.81:2.54:76.82:6.90.The water-soluble glucose oligosaccharide prepared by the application can obviously improve the symptoms of alcoholic liver, and has the effects of inhibiting liver damage and improving the activity of liver antioxidant enzymes.In addition, the Luzhou-flavor dreg in the application is a by-product of liquor fermentation, has high raw material yield and low cost, and the application can improve the resource utilization value of the dreg.
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