Pharmaceutical composition for treating chyluria as well as preparation method and application thereof
By using a specific proportion of pharmaceutical compositions, including Chinese medicinal materials such as cyperus, cereal, and Poria cocos, a drug preparation for chylouria treatment was formed, which solved the problems of poor effect and major side effects of existing therapeutic drugs, and achieved a significant improvement of chylouria symptoms without side effects.
Patent Information
- Application Number
- CN202411653372.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-19
- Publication Date
- 2025-03-07
Smart Images
Figure SMS_1
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of traditional Chinese medicine, and in particular to a pharmaceutical composition for treating chyluria, a preparation method thereof, and an application thereof. Background Art
[0002] Chylous urine refers to the phenomenon that the chyle (liquid after fat saponification) absorbed from the intestine cannot be drained into the blood through the normal lymphatic channels, but flows back into the lymphatic vessels of the urinary system, causing the internal pressure of the lymphatic vessels to increase, become varicose, and rupture, and the chyle overflows into the urine, making the urine milky white. Chylous urine appears milky white or cheese-like, and its main components are triglycerides, albumin, lecithin, cholesterol, fibrin, etc. The appearance color and turbidity are related to the chyle content, and are affected by the fat content of the patient's diet, exercise, body position, and the degree of damage to the lymphatic vessels. Severe chyluria can be divided into three layers after standing: the upper layer is fat; the middle layer is milky white liquid, often accompanied by coagulation; the lower layer is a pink precipitate containing red blood cells and white blood cells. Chylous urine accompanied by hematuria is chylohematuria, and chylopururia is accompanied by pyuria.
[0003] Chylous urine has the characteristics of high incidence, difficult cure, high recurrence rate after recovery, and is accompanied by multiple complications. The current treatment methods mainly rely on surgical treatment, Western medicine treatment, or drugs such as water centipede granules to improve symptoms. However, the treatment effect is poor and there are many side effects. Summary of the invention
[0004] The purpose of the embodiments of the present application is to provide a pharmaceutical composition for treating chyluria, aiming to solve the problem that existing drugs for treating chyluria have poor therapeutic effects and many side effects.
[0005] The embodiment of the present application is implemented as follows: a pharmaceutical composition for treating chyluria comprises the following raw materials in parts by weight:
[0006] 10-15 parts of Radix Dioscoreae, 5-10 parts of Semen Plantaginis, 10-15 parts of Poria, 1.5-3 parts of Plumula Nelumbinis, 5-8 parts of Acorus Tatarinowii, 3-10 parts of Cortex Phellodendri, 5-15 parts of Salvia miltiorrhiza, 5-15 parts of Atractylodes macrocephala, 0.3-3 parts of Antelope Horn and 3-20 parts of Anoectochilus roxburghii.
[0007] Another object of an embodiment of the present application is a pharmaceutical preparation formed by using the above-mentioned pharmaceutical composition for treating chyluria.
[0008] Another object of the present invention is to provide a method for preparing a pharmaceutical preparation for treating chyluria, comprising:
[0009] According to the formula of the pharmaceutical composition for treating chyluria, weigh out various raw materials and set aside;
[0010] Mix Radix Dioscoreae, Semen Plantaginis, Poria, Lotus Seed Heart, Acorus Tatarinowii, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Atractylodes Macrocephalae, Antelope Horn and Anoectochilus Roxb., add 400-600 mL of water and boil until 150-250 mL is left, and filter to obtain a first medicament and a first dregs;
[0011] Add 300-500 mL of water to the first medicinal residue and boil until 150-250 mL is reached, and filter to obtain a second medicament and a second medicinal residue;
[0012] The second medicinal residue is added to 200-400 mL of water and boiled to 150-250 mL, and filtered to obtain a third medicament.
[0013] Another object of an embodiment of the present application is to use the above-mentioned pharmaceutical composition for treating chyluria in the preparation of a drug for treating chyluria.
[0014] The embodiment of the present application provides a pharmaceutical composition for treating chyluria, which applies the principle of combining the four diagnostic methods of traditional Chinese medicine and treating based on syndrome differentiation. It is prepared by rationally combining Radix Dipterocarpifolia, Semen Plantaginis, Poria, Phellodendron chinense, Rhizoma Acoruscae, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis Macrocephalae, Horn of the Antelope and Rhizoma Anoectochilus in specific proportions. The various drugs interact with each other and enhance their effects synergistically. It has the effects of clearing away heat and dampness, and separating the clear from the turbid, and has a significant improvement effect on chyluria without any side effects. DETAILED DESCRIPTION
[0015] In order to make the purpose, technical solution and advantages of the present application more clear, the present application is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described here are only used to explain the present application and are not used to limit the present application.
[0016] The present application provides a pharmaceutical composition for treating chyluria, comprising the following raw materials in parts by weight:
[0017] 10-15 parts of Radix Dioscoreae, 5-10 parts of Semen Plantaginis, 10-15 parts of Poria, 1.5-3 parts of Plumula Nelumbinis, 5-8 parts of Acorus Tatarinowii, 3-10 parts of Cortex Phellodendri, 5-15 parts of Salvia miltiorrhiza, 5-15 parts of Atractylodes macrocephala, 0.3-3 parts of Antelope Horn and 3-20 parts of Anoectochilus roxburghii.
[0018] Among them, Dioscorea is a twining herbaceous vine with horizontal rhizomes, irregularly long cylindrical, and yellow-brown outer skin. The stem is left-handed and glabrous. The leaves are alternate and slightly leathery. The leaves at the base of the stem are palmately lobed, 7-lobed, of varying sizes, deeply cordate at the base, and ovate-triangular above the middle, with wavy edges or entire margins, gradually pointed at the apex, deeply cordate or broadly cordate at the base, with obvious reticulate veins on the back, and sparse white prickles along the veins on both sides. The flowers are unisexual and dioecious. The male inflorescence is racemose, usually branched in panicles, solitary or clustered in 2-3 in the leaf axils; the male flowers are pedunculate, the perianth is clear yellow when fresh, black after drying, 4-5 mm long, united at the base, 6-lobed at the apex, and the lobes are oval; there are 6 stamens, sometimes only 3 are developed, attached to the base of the perianth tube, with degenerate pistils. The female inflorescence is similar to the male inflorescence; the female perianth is 6-lobed, the anthers of the degenerate stamens are incomplete or only have filaments. The capsule is triangular, each rib is wing-shaped, semicircular, 1.5-1.8 cm long, 1-1.2 cm wide; the seeds are oblate, 4-5 mm in diameter, born in the middle of the axis of each room, and have film-like wings around them when mature. The flowering period is June-July, and the fruiting period is July-October. It has the effects of dispelling wind and dampness. It can treat rheumatism, pain in the waist and knees, urinary incontinence, stranguria, spermatorrhea, and damp-heat sores.
[0019] Among them, Plantago seed is a perennial herb, which is the mature seed of Plantago or Plantago asiatica of the Plantaginaceae family. It is oval or irregularly oblong or triangular oblong, slightly flat, about 2 mm long and 1 mm wide, with light brown or dark brown or brown surface, fine wrinkles, and a grayish white concave hilum on one side. It is hard and the cut surface is grayish white. It becomes sticky, slippery and swollen when it meets water, with a slight smell and a light taste. It is sticky when chewed. Large, full and brown-red are the best. The flower stem is up to 50 mm high and has fibrous roots. The leaves are root-born, with long petioles, almost as long as or longer than the leaves, and the base is enlarged; the leaves are ovate or elliptical, 4 to 12 cm long and 2 to 7 cm wide, with sharp or blunt tips, narrow bases and long petioles, entire or irregularly wavy shallow teeth, usually with 5 to 7 arc-shaped veins. It has the effects of clearing heat, improving eyesight and removing phlegm. It is effective in treating urinary obstruction, stranguria, leucorrhea, hematuria, summer-heat and dampness diarrhea, cough with sputum, dampness and arthralgia, and red eyes and cataracts.
[0020] Among them, Poria cocos is the dried sclerotium of the fungus Poria cocos of the family Famillopodiaceae. It often parasitizes on the roots of pine trees. It is shaped like a sweet potato, spherical, with a light brown or dark brown outer skin and pink or white inside. It is often used for edema, oliguria, phlegm and fluid, dizziness and palpitations, spleen deficiency, poor appetite, loose stools and diarrhea, restlessness, palpitations and insomnia.
[0021] Among them, lotus seed core is the dried young leaves and embryonic roots of the mature seeds of the lotus plant of the Nymphaeaceae family. It has the effects of clearing the heart and calming the mind, relieving cough and reducing phlegm, lowering blood lipids, stopping bleeding and anti-inflammatory, anti-oxidation, anti-thrombosis, protecting the liver, lungs and kidneys, and protecting the central nervous system.
[0022] Among them, Acorus calamus is a perennial herb with a fragrant rhizome, 2-5 mm thick, light brown on the outside, 3-5 mm long internodes, fleshy roots, many fibrous roots, densely branched upper rhizomes, so the plant grows in clusters, and the branches are often fibrous and persistent at the leaf base. Acorus calamus is pungent, bitter, warm in nature, can open the mind and resolve phlegm, ward off filth and kill insects. It is mainly used to treat phlegm retention, unclear consciousness, chronic tracheitis; dysentery, enteritis, abdominal distension and pain, loss of appetite, wind-cold-dampness arthralgia, and external application for sores and scabies.
[0023] Among them, Phellodendron chinense is in the form of plates or shallow grooves, with yellow-brown or yellow-brown outer surface, flat or with longitudinal grooves, and some with visible lenticels and residual gray-brown rough skin. The inner surface is dark yellow or light brown with fine longitudinal ridges. It is light, hard, fibrous in cross section, flaky and layered, dark yellow. It has a slight smell and tastes very bitter, and is sticky when chewed. It clears away heat and dampness, purges fire and detoxifies, removes bone steaming and clears deficiency heat. It is used for damp-heat diarrhea, jaundice, leucorrhea, hot stranguria, beriberi, paralysis, bone steaming and fatigue fever, night sweats, spermatorrhea, sores and swelling, and eczema and itching. Salted Phellodendron chinense nourishes yin and reduces fire. It is used for yin deficiency and excessive fire, night sweats and bone steaming.
[0024] Among them, Salvia miltiorrhiza, a perennial herb of the genus Salvia of the family Lamiaceae, has the effects of removing blood stasis, promoting new blood, promoting blood circulation, and regulating menstruation. It is an important medicine for gynecology, mainly treating uterine bleeding, irregular menstruation, blood stasis and other diseases, and has a good effect on the treatment of coronary heart disease. In addition, it can also treat neurasthenia, insomnia, joint pain, anemia and other diseases, and can be used externally to wash lacquer sores.
[0025] Among them, Atractylodes macrocephala is an important bulk Chinese medicinal material. The dried rhizome of Atractylodes macrocephala, a perennial herb of the Asteraceae family, has many medicinal functions such as tonifying the spleen and stomach, drying dampness and promoting diuresis, stopping sweat and stabilizing the fetus.
[0026] Among them, antelope horns are the horns of male Saiga antelopes, which belong to the genus Antelope of the Bovidae family. Antelope horns have the effects of calming the liver and calming wind, clearing the liver and improving eyesight, clearing away heat and detoxifying. They are mainly used to treat internal liver wind movement, convulsions and convulsions; hyperactivity of liver yang, dizziness and vertigo; inflammation of liver fire, red eyes and headache; high fever and coma in febrile diseases, heat toxicity and spots; carbuncle, sore and ulcer, excessive heat and toxicity in the blood, rheumatism and heat arthralgia, lung heat cough and asthma, whooping cough, etc.
[0027] Among them, golden thread vine can also be called golden earrings and golden thread. It has the effects of purging heat, reducing swelling and relieving pain, promoting blood circulation of skin cells, protecting the integrity of liver cell membranes, and can treat bronchitis, tuberculosis, hypertension, cerebral stroke, heart disease, and arteriosclerosis.
[0028] Preferably, the pharmaceutical composition for treating chyluria comprises the following raw materials in parts by weight:
[0029] 11-13 parts of Radix Dioscoreae, 6-9 parts of Semen Plantaginis, 11-13 parts of Poria, 1.5-2.5 parts of Pelvis Nelumbinis, 6-7 parts of Acorus Tatarinowii, 5-7 parts of Phellodendron Amurense, 8-12 parts of Salvia miltiorrhiza, 8-12 parts of Atractylodes macrocephala, 1-2 parts of Horn of Antelope and 5-15 parts of Anoectochilus roxburghii.
[0030] Preferably, the pharmaceutical composition for treating chyluria is characterized by comprising the following raw materials in parts by weight:
[0031] 12 parts of Radix Dioscoreae, 7.5 parts of Semen Plantaginis, 12 parts of Poria, 2 parts of Pelvis Nelumbinis, 6.5 parts of Acorus Tatarinowii, 6 parts of Cortex Phellodendri, 10 parts of Salvia miltiorrhiza, 10 parts of Atractylodes macrocephala, 1.5 parts of Horn of Antelope and 10 parts of Anoectochilus roxburghii.
[0032] Preferably, when the patient is a child or an elderly person, a low-dose treatment regimen is preferably used, that is, the pharmaceutical composition for treating chyluria comprises the following raw materials in parts by weight:
[0033] 10 parts of Radix Dioscoreae, 5 parts of Semen Plantaginis, 10 parts of Poria, 1.5 parts of Pelvis Nelumbinis, 5 parts of Acorus Tatarinowii, 3 parts of Cortex Phellodendri, 5 parts of Salvia miltiorrhiza, 5 parts of Atractylodes macrocephala, 0.3 parts of Horn of Antelope and 3 parts of Anoectochilus roxburghii.
[0034] Preferably, when the patient is an adult with severe symptoms, a high-dose treatment regimen is adopted, that is, the pharmaceutical composition for treating chyluria comprises the following raw materials in parts by weight:
[0035] 15 parts of Radix Dioscoreae, 10 parts of Semen Plantaginis, 15 parts of Poria, 3 parts of Plumula Nelumbinis, 8 parts of Acorus Tatarinowii, 10 parts of Cortex Phellodendri, 15 parts of Salvia miltiorrhiza, 15 parts of Atractylodes macrocephala, 3 parts of Horn of Antelope and 20 parts of Anoectochilus roxburghii.
[0036] The embodiment of the present application provides a pharmaceutical preparation formed by the above-mentioned pharmaceutical composition for treating chyluria.
[0037] Wherein, the pharmaceutical preparation is selected from one of powder, granule, tablet, capsule, solution and suspension.
[0038] The present application also provides a method for preparing the above-mentioned pharmaceutical preparation for treating chyluria, comprising:
[0039] According to the formula of the pharmaceutical composition for treating chyluria, weigh out various raw materials and set aside;
[0040] Mix Radix Dioscoreae, Semen Plantaginis, Poria, Lotus Seed Heart, Acorus Tatarinowii, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Atractylodes Macrocephalae, Antelope Horn and Anoectochilus Roxb., add 400-600 mL of water and boil until 150-250 mL is left, and filter to obtain a first medicament and a first dregs;
[0041] Add 300-500 mL of water to the first medicinal residue and boil until 150-250 mL is reached, and filter to obtain a second medicament and a second medicinal residue;
[0042] The second medicinal residue is added to 200-400 mL of water and boiled to 150-250 mL, and filtered to obtain a third medicament.
[0043] Preferably, after mixing Radix Dioscoreae, Semen Plantaginis, Poria, Phellodendron, Acorus Gramineus, Phellodendron Amurense, Salvia Miltiorrhiza, Atractylodes Macrocephala, Antelope Horn and Anoectochilus Roxb., 500 mL of water is added and boiled to 200 mL, and filtered to obtain the first medicament.
[0044] Preferably, the first medicinal residue is added to 400 mL of water and boiled to 200 mL, and filtered to obtain the second medicament and the second medicinal residue;
[0045] Preferably, the second medicinal residue is added into 300 mL of water and boiled to 200 mL, and filtered to obtain the third medicament.
[0046] The above-mentioned medicine is taken in one dose per day, with the first dose taken in the morning, the second dose taken at noon, and the third dose taken in the evening.
[0047] The embodiment of the present application also provides a use of the above-mentioned pharmaceutical composition for treating chyluria in the preparation of a drug for treating chyluria.
[0048] The pharmaceutical composition for treating chyluria is described in detail with specific examples, as shown below. The methods used in the following examples are conventional methods unless otherwise specified; the materials used are commercially available unless otherwise specified.
[0049] Example 1
[0050] In this embodiment, a pharmaceutical composition for treating chyluria includes the following raw materials by weight:
[0051] 10g of Radix Dioscoreae, 5g of Plantago, 10g of Poria, 1.5g of Lotus Seed Heart, 5g of Acorus Gramineus, 3g of Phellodendron Amurense, 5g of Salvia Miltiorrhiza, 5g of Atractylodes Macrocephala, 0.3g of Antelope Horn and 3g of Noxious Thread Lotus.
[0052] According to the formula of the pharmaceutical composition for treating chyluria, weigh out various raw materials and set aside;
[0053] Mix Radix Dioscoreae, Semen Plantaginis, Poria, Lotus Seed Heart, Acorus Tatarinowii, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Atractylodes Macrocephalae, Horn of Antelope and Anoectochilus Roxb. Add 500 mL of water and boil until 200 mL is obtained, and filter to obtain a first medicament and a first medicinal residue;
[0054] Add 400 mL of water to the first medicinal residue and boil until the residue reaches 200 mL, and filter to obtain a second medicament and a second medicinal residue;
[0055] The second medicinal residue was added into 300 mL of water and boiled until the residue reached 200 mL. The residue was filtered to obtain the third medicament.
[0056] Example 2
[0057] In this embodiment, a pharmaceutical composition for treating chyluria includes the following raw materials by weight:
[0058] 15g of Radix Dioscoreae, 10g of Plantago, 15g of Poria, 3g of Lotus Seed Heart, 8g of Acorus Gramineus, 10g of Phellodendron Amurense, 5-15g of Salvia Miltiorrhiza, 15g of Atractylodes Macrocephala, 3g of Antelope Horn and 20g of Anoectochilus Roxb.
[0059] According to the formula of the pharmaceutical composition for treating chyluria, weigh out various raw materials and set aside;
[0060] Mix Radix Dioscoreae, Semen Plantaginis, Poria, Lotus Seed Heart, Acorus Tatarinowii, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Atractylodes Macrocephalae, Horn of Antelope and Anoectochilus Roxb. Add 500 mL of water and boil until 200 mL is obtained, and filter to obtain a first medicament and a first medicinal residue;
[0061] Add 400 mL of water to the first medicinal residue and boil until the residue reaches 200 mL, and filter to obtain a second medicament and a second medicinal residue;
[0062] The second medicinal residue was added into 300 mL of water and boiled until the residue reached 200 mL. The residue was filtered to obtain the third medicament.
[0063] Example 3
[0064] In this embodiment, a pharmaceutical composition for treating chyluria includes the following raw materials by weight:
[0065] 11g of Radix Dioscoreae, 6g of Plantago, 11g of Poria, 1.5g of Lotus Seed Heart, 6g of Acorus Tatarinowii, 5g of Phellodendron Amurense, 8g of Salvia miltiorrhiza, 8g of Atractylodes macrocephala, 1g of Antelope Horn and 5g of Anoectochilus roxburghii.
[0066] According to the formula of the pharmaceutical composition for treating chyluria, weigh out various raw materials and set aside;
[0067] Mix Radix Dioscoreae, Semen Plantaginis, Poria, Lotus Seed Heart, Acorus Tatarinowii, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Atractylodes Macrocephalae, Horn of Antelope and Anoectochilus Roxb. Add 500 mL of water and boil until 200 mL is obtained, and filter to obtain a first medicament and a first medicinal residue;
[0068] Add 400 mL of water to the first medicinal residue and boil until the residue reaches 200 mL, and filter to obtain a second medicament and a second medicinal residue;
[0069] The second medicinal residue was added into 300 mL of water and boiled until the residue reached 200 mL. The residue was filtered to obtain the third medicament.
[0070] Example 4
[0071] In this embodiment, a pharmaceutical composition for treating chyluria includes the following raw materials by weight:
[0072] 13g of Radix Dioscoreae, 9g of Plantago, 13g of Poria, 2.5g of Lotus Seed Heart, 7g of Acorus Gramineus, 7g of Phellodendron Amurense, 12g of Salvia Miltiorrhiza, 12g of Atractylodes Macrocephala, 2g of Antelope Horn and 15g of Anoectochilus Roxb.
[0073] According to the formula of the pharmaceutical composition for treating chyluria, weigh out various raw materials and set aside;
[0074] Mix Radix Dioscoreae, Semen Plantaginis, Poria, Lotus Seed Heart, Acorus Tatarinowii, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Atractylodes Macrocephalae, Horn of Antelope and Anoectochilus Roxb. Add 500 mL of water and boil until 200 mL is obtained, and filter to obtain a first medicament and a first medicinal residue;
[0075] Add 400 mL of water to the first medicinal residue and boil until the residue reaches 200 mL, and filter to obtain a second medicament and a second medicinal residue;
[0076] The second medicinal residue was added into 300 mL of water and boiled until the residue reached 200 mL. The residue was filtered to obtain the third medicament.
[0077] Example 5
[0078] In this embodiment, a pharmaceutical composition for treating chyluria includes the following raw materials by weight:
[0079] 12g of Radix Dioscoreae, 7.5g of Plantago, 12g of Poria, 2g of Lotus Seed Heart, 6.5g of Acorus Gramineus, 6g of Phellodendron Amurense, 10g of Salvia Miltiorrhiza, 10g of Atractylodes Macrocephala, 1.5g of Antelope Horn and 10g of Anoectochilus Roxb.
[0080] According to the formula of the pharmaceutical composition for treating chyluria, weigh out various raw materials and set aside;
[0081] Mix Radix Dioscoreae, Semen Plantaginis, Poria, Lotus Seed Heart, Acorus Tatarinowii, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Atractylodes Macrocephalae, Horn of Antelope and Anoectochilus Roxb. Add 500 mL of water and boil until 200 mL is obtained, and filter to obtain a first medicament and a first medicinal residue;
[0082] Add 400 mL of water to the first medicinal residue and boil until the residue reaches 200 mL, and filter to obtain a second medicament and a second medicinal residue;
[0083] The second medicinal residue was added into 300 mL of water and boiled until the residue reached 200 mL. The residue was filtered to obtain the third medicament.
[0084] The following are the results of the therapeutic effects of 145 patients with chyluria using the pharmaceutical composition of the present application example for treating chyluria, as shown in Table 1-2.
[0085] Treatment method: 39 children with chyluria were treated with the low-dose pharmaceutical composition of Example 1, and 106 adult patients with chyluria (aged between 30 and 65 years old) were treated with the high-dose pharmaceutical composition of Example 2. The dosage was three times a day, orally, one dose was taken for one day, the first dose was taken in the morning, the second dose was taken at noon, and the third dose was taken in the evening. The treatment cycle was 30 days, and the patients with significant effects were observed for 6 months.
[0086] Table 1 Efficacy evaluation criteria
[0087] Efficacy Evaluation Criteria Significant effect After treatment, the urine color turned clear, and there was no obvious recurrence within 6 months. efficient The urine color becomes clearer, but sometimes there is turbid urine invalid No significant improvement in cloudy urine
[0088] Table 2 Statistical results of efficacy
[0089]
[0090] Some typical cases are as follows:
[0091] Case 1: Chen, female, 64 years old, a rural resident of Putian City, Fujian Province, on August 15, 2019, complained that due to long-term farm labor in rural areas, the urine was turbid and similar to tofu paddle urine. When exaggerated, the urine may contain clots, floating oil, or blood, or blood streaks, blood clots, and occasional astringent and hot feeling in the urethra, but no pain. Everything else is normal, which has been going on for several years. First, she did not pay much attention to the disease, and second, she dared not tell her children until she had delayed for a long time. So, she went to see a doctor everywhere, but there was no sign of improvement. Finally, she went to a hospital in Putian City for more than ten days of hospitalization and was diagnosed with chyluria. In short, she took medicine, had an IV drip, and was hospitalized for recuperation, but the effect was not satisfactory. Finally, by mistake, she came to see a doctor inexplicably and took the medicine of this application for fifteen days and 15 doses, and the effect was very satisfactory. Subsequently, she took the medicine for about two months from time to time and recovered. After that, she was prevented and no recurrence was seen.
[0092] Case 2:
[0093] Lin, female, 62 years old, teacher. On March 22, 2020, the main complaint: suffering from chronic anicteric hepatitis for more than 20 years, and going through hardships. In recent years, the urine has been turbid for a long time, the urine color is milky white like coagulation or jelly, the energy is weak, and gradually loses weight and becomes weak, accompanied by sore waist and weak knees, dizziness, tinnitus, irritability, dry mouth, red tongue, and thin pulse. After taking the medicine of this application for half a month, the effect is significant. After that, follow-up for two months, and continue to take the medicine of this application for more than a month from time to time, and now it is cured.
[0094] Case 3: Zhan, female, 55 years old, retired cadre. On April 8, 2021, the main complaint: Suffering from gynecological breast hyperplasia and thyroiditis for more than ten years, she retired early after much hardship. Due to repeated attacks of chyluria, which did not heal over time, the urine was turbid like white pulp, or like rice water, accompanied by lower abdominal distension, poor urination, dull complexion, fatigue, fatigue, or greasy food, it would attack or worsen. The tongue was pale and the pulse was weak. Recommended by a friend, I took 25 doses of the medicine of this application, and the effect was immediate. After that, I followed up for three months and took the medicine of this application for two months at irregular intervals. I have been cured and there has been no recurrence.
[0095] The above-mentioned embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.
[0096] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present application should be included in the protection scope of the present application.
Claims
1. A pharmaceutical composition for treating chyluria, characterized in that: The invention comprises the following raw materials in parts by weight: 10-15 parts of Radix Dioscoreae, 5-10 parts of Semen Plantaginis, 10-15 parts of Poria, 1.5-3 parts of Plumula Nelumbinis, 5-8 parts of Acorus Tatarinowii, 3-10 parts of Cortex Phellodendri, 5-15 parts of Salvia miltiorrhiza, 5-15 parts of Atractylodes macrocephala, 0.3-3 parts of Antelope Horn and 3-20 parts of Anoectochilus roxburghii.
2. The pharmaceutical composition for treating chyluria according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 11-13 parts of Radix Dioscoreae, 6-9 parts of Semen Plantaginis, 11-13 parts of Poria, 1.5-2.5 parts of Pelvis Nelumbinis, 6-7 parts of Acorus Tatarinowii, 5-7 parts of Phellodendron Amurense, 8-12 parts of Salvia miltiorrhiza, 8-12 parts of Atractylodes macrocephala, 1-2 parts of Horn of Antelope and 5-15 parts of Anoectochilus roxburghii.
3. The pharmaceutical composition for treating chyluria according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 12 parts of Radix Dioscoreae, 7.5 parts of Semen Plantaginis, 12 parts of Poria, 2 parts of Pelvis Nelumbinis, 6.5 parts of Acorus Tatarinowii, 6 parts of Cortex Phellodendri, 10 parts of Salvia miltiorrhiza, 10 parts of Atractylodes macrocephala, 1.5 parts of Horn of Antelope and 10 parts of Anoectochilus roxburghii.
4. The pharmaceutical composition for treating chyluria according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 10 parts of Radix Dioscoreae, 5 parts of Semen Plantaginis, 10 parts of Poria, 1.5 parts of Pelvis Nelumbinis, 5 parts of Acorus Tatarinowii, 3 parts of Cortex Phellodendri, 5 parts of Salvia miltiorrhiza, 5 parts of Atractylodes macrocephala, 0.3 parts of Horn of Antelope and 3 parts of Anoectochilus roxburghii.
5. The pharmaceutical composition for treating chyluria according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 15 parts of Radix Dioscoreae, 10 parts of Semen Plantaginis, 15 parts of Poria, 3 parts of Plumula Nelumbinis, 8 parts of Acorus Tatarinowii, 10 parts of Cortex Phellodendri, 15 parts of Salvia miltiorrhiza, 15 parts of Atractylodes macrocephala, 3 parts of Horn of Antelope and 20 parts of Anoectochilus roxburghii.
6. A pharmaceutical preparation formed by using the pharmaceutical composition for treating chyluria according to any one of claims 1 to 5.
7. The pharmaceutical preparation according to claim 6, characterized in that The pharmaceutical preparation is selected from one of powders, granules, tablets, capsules, solutions and suspensions.
8. A method for preparing a pharmaceutical preparation for treating chyluria, characterized in that: include: Weigh the raw materials according to the formula of the pharmaceutical composition for treating chyluria according to any one of claims 1 to 5 and set aside; Mix Radix Dioscoreae, Semen Plantaginis, Poria, Lotus Seed Heart, Acorus Tatarinowii, Cortex Phellodendri, Radix Salviae Miltiorrhizae, Atractylodes Macrocephalae, Antelope Horn and Anoectochilus Roxb., add 400-600 mL of water and boil until 150-250 mL is left, and filter to obtain a first medicament and a first dregs; Add 300-500 mL of water to the first medicinal residue and boil until 150-250 mL is reached, and filter to obtain a second medicament and a second medicinal residue; The second medicinal residue is added to 200-400 mL of water and boiled to 150-250 mL, and filtered to obtain a third medicament.
9. Use of the pharmaceutical composition for treating chyluria according to any one of claims 1 to 5 in preparing a drug for treating chyluria.