A fully automated chemiluminescence analyzer

Abstract

This invention discloses a fully automated chemiluminescence analyzer, comprising a frame, a feeding module, a pipette module, a sample and reagent module, and a pipette tip storage module. The frame has a worktable with a storage area and a feeding channel. The cup feeding module pushes reaction cups from the storage area into the feeding channel and sequentially through each station along the channel. The pipette module, sample and reagent module, and pipette tip storage module are respectively mounted on the frame. The pipette module is used to aspirate and displace liquid from the reaction cups, the sample and reagent module is used to hold samples and reagents, and the pipette tip storage module is used to store pipette tips. Multiple stations are provided on the feeding channel, allowing the entire detection to be completed through a single channel, reducing the number of channels and space occupancy. The pipette module replaces the air pump and pipette tip retraction structure, effectively reducing costs and space occupancy. This makes the fully automated chemiluminescence analyzer compact and more economical.

Description

Technical Field

[0001] This invention relates to the field of detection equipment technology, specifically to a fully automated chemiluminescence analyzer. Background Technology

[0002] Currently, fully automated chemiluminescence analyzers on the market are usually high-speed instruments, suitable for high-volume testing scenarios, and have a large footprint. With the development of technology and the different testing needs, the demand for low-throughput, miniature fully automated chemiluminescence analyzers is also constantly increasing. Summary of the Invention

[0003] The technical problem to be solved by the present invention is that the existing fully automated chemiluminescence analyzers occupy a large space. The purpose is to provide a fully automated chemiluminescence analyzer to solve the above-mentioned problem.

[0004] This invention is achieved through the following technical solution:

[0005] A fully automated chemiluminescence analyzer includes a frame, a feeding module, a pipette module, a sample reagent module, and a pipette tip storage module;

[0006] The frame has a worktable with interconnected storage areas and feed channels. The storage areas are used to store reaction cups, and the feed channels have several stations and corresponding experimental equipment.

[0007] The cup feeding module is used to push the reaction cup so that the reaction cup enters the feed channel from the storage area and passes through each station in sequence along the feed channel;

[0008] The pipette module, sample and reagent module, and pipette tip storage module are respectively mounted on the rack. The pipette module is used to aspirate and displace liquid from the reaction cup, the sample and reagent module is used to place samples and reagents, and the pipette tip storage module is used to store pipette tips.

[0009] In one possible design, the feed module includes a first feed unit located in the storage area and a second feed unit located in the feed channel;

[0010] Both the first and second feed units include a drive motor, a synchronous belt, a transmission plate, and a pusher. The output end of the drive motor is connected to the synchronous belt, which is parallel to the storage area or the feed channel. The transmission plate is connected to the synchronous belt and the pusher so that the pusher moves along the storage area or the feed channel.

[0011] Accordingly, the first feed unit includes two pushers respectively disposed on both sides of the storage area and facing each other, and the second feed unit includes several pushers spaced apart along the length of the transmission plate.

[0012] In one possible design, the pusher component includes a base plate, a base rod, a push plate, and a limiting rod.

[0013] The base plate is used to connect the transmission plate, and the base rod is set on the base plate;

[0014] One end of the push plate is configured as a rotating end that is rotatably mounted on the base rod by a torsion spring, and the other end of the push plate is configured as a pushing end that extends to the outside of the base plate. Along the pushing direction, the push plate gradually tilts from the rotating end to the pushing end. Accordingly, the push plate can rotate around the base rod.

[0015] The limiting rod is disposed on the base plate and located on the side of the push plate. Along the pushing direction, the limiting rod is located downstream of the push plate. Accordingly, the limiting rod is used to limit the range of rotation of the push plate.

[0016] In one possible design, a guide plate is provided on each side of the storage area, and correspondingly, the two ends of the reaction cup are provided with matching guide grooves.

[0017] The feed channel is equipped with a cover plate, which has several through holes. Each through hole corresponds to a workstation.

[0018] The feed channel is provided with several spaced positioning components, each including a positioning rod and a positioning spring. One end of the positioning rod extends into the feed channel and can be inserted into the positioning groove. The other end of the positioning rod is connected to the feed channel through the positioning spring. Correspondingly, the side of the reaction cup is provided with a positioning groove adapted to the positioning rod, and the contact surfaces of the positioning rod and the positioning groove are both constructed as arc surfaces.

[0019] In one possible design, the storage area and the sample reagent module are spaced apart. Accordingly, the storage area and the sample reagent module are respectively provided with a feed channel and a pipette tip storage module on both sides. The storage area is vertical and connected to the end of the feed channel.

[0020] A reaction cup is placed on the workbench. The reaction cup includes a base and a cup body. The base has several spaced insertion holes, and the cup body has several insertion holes that are inserted into the insertion holes respectively. Correspondingly, the base has an additional fixing bracket located above the insertion holes. The fixing bracket has several fixing holes. The insertion holes, fixing holes and cup body are set one-to-one.

[0021] Correspondingly, the guide groove is located on the outer wall surface at both ends of the base, and several positioning grooves are provided and spaced apart on the side of the base. The base is also provided with guide surfaces at both ends, with two guide surfaces located on the upper and lower sides of the guide groove respectively.

[0022] In one possible design, the pipette module includes a triaxial module and a pipette.

[0023] The three-axis module includes an X-axis module, a Y-axis module, and a Z-axis module connected in sequence. The Z-axis module is connected to the pipette via an additional plate.

[0024] The pipette includes a base, a pipette tip, and a piston unit. The base is detachably connected to the pipette tip via a gourd head. The piston unit is reciprocally slidably mounted on the base. The piston unit is used for the pipette tip to aspirate and dissipate liquid and to retract the pipette tip. Correspondingly, the gourd head is provided with an intermediate hole for connecting the base and the pipette tip.

[0025] Correspondingly, the auxiliary plate is equipped with a driver for driving the piston rod to slide back and forth along the base cylinder;

[0026] The piston unit includes a piston rod, a guide shaft, and a suction head pusher plate;

[0027] The piston rod passes through the base cylinder and can slide back and forth along the base cylinder. The piston rod is positioned opposite to the hoist head. Correspondingly, one end of the base cylinder is closed by the piston rod, and the other end is connected to the outside through the middle hole on the hoist head.

[0028] The guide shaft passes through the base cylinder and is parallel to the axis of the base cylinder. The two ends of the guide shaft are connected to the piston rod and the suction head push plate, respectively. Correspondingly, the base cylinder is provided with mounting holes adapted to the guide shaft.

[0029] The suction head push plate is sleeved on the gourd head and can slide back and forth along the gourd head;

[0030] Furthermore, the piston rod is equipped with a baffle plate, and the suction head push plate includes a suction retraction part sleeved on the hoist head and a baffle part connected to the suction retraction part. The two ends of the guide shaft are detachably connected to the baffle plate and the baffle part by screws.

[0031] At least two guide shafts are provided and evenly distributed on the base cylinder, and each guide shaft is fitted with a spring, which is located in the mounting hole.

[0032] In one possible design, the sample reagent module includes a lower plate, a storage plate, and a mixing mechanism;

[0033] The lower plate and the storage plate are detachably connected, and one end of the lower plate is connected to the mixing mechanism; the storage plate is provided with at least one reagent position and at least one sample position;

[0034] The mixing mechanism includes a mixing motor and a placement box connected to the lower base plate. The mixing motor is fixed on the bottom surface of the lower base plate, and the placement box is set on the top surface of the lower base plate. The output end of the mixing motor passes through the lower base plate and is connected to the placement box. Correspondingly, the placement box is provided with a placement slot adapted to the reagent kit, and the storage plate is provided with an inner groove adapted to the placement box.

[0035] In one possible design, the test equipment includes a pumping unit for waste liquid discharge, a detection unit for sample testing, and a mixing unit for liquid homogenization.

[0036] The feed channel is equipped with a heating film laid along the feed channel, a temperature sensor for monitoring the temperature of the feed channel, and an overheat protector for preventing overheating. The heating film, temperature sensor, and overheat protector are electrically connected and form a heating unit.

[0037] In one possible design, the liquid extraction unit includes a first motor, a first intermediate plate and a liquid extraction needle. The first motor is connected to the first intermediate plate via a threaded rod. The first intermediate plate is connected to the liquid extraction needle and can move along the threaded rod. The liquid extraction needle is disposed on the first intermediate plate and located above one of the workstations.

[0038] The detection unit includes a second motor, a second intermediate plate, and a detector. The second motor is connected to the second intermediate plate via a threaded rod. The second intermediate plate is connected to the detector and can move along the threaded rod. The liquid extraction needle is set on the second intermediate plate and located above one of the workstations.

[0039] In one possible design, the mixing unit includes a third motor, a drive gear, a driven rack, and a magnetic part. The third motor is mounted on the frame, and its output shaft is connected to the drive gear. The drive gear meshes with the driven rack. The magnetic part is mounted on the driven rack and located outside the feed channel. Correspondingly, a suitable magnetic attraction part is placed inside the reaction cup.

[0040] The passive rack can reciprocate under the drive of the active gear, so as to drive the magnetic part to move up and down relative to the feed channel, so that the magnetic suction part moves in the reaction cup and mixes the liquid.

[0041] Two passive racks are provided and located on both sides of the driving gear. Correspondingly, two magnetic parts are provided and located on both sides of the feed channel, so that the magnetic attraction part moves back and forth in the reaction cup and mixes the liquid.

[0042] Compared with the prior art, the present invention has the following advantages and beneficial effects:

[0043] 1. The rack provides installation space for other functional modules, so that the feeding module, pipette module, sample reagent module, pipette tip storage module and related test equipment can be integrated on the rack. This achieves miniaturization while completing the test, making the fully automated chemiluminescence analyzer more compact and economical, and helping to reduce economic costs.

[0044] 2. The feed channel has multiple stations, so the entire inspection can be completed through a single channel, reducing the number of channels and space occupation; and the second feed unit pushes multiple reaction cups to move within the feed channel, enabling multiple inspections to be carried out simultaneously, which effectively improves the inspection efficiency.

[0045] 3. In the pipette module, the piston unit reciprocates and slides on the base cylinder. During this reciprocating motion, the piston unit creates negative or positive pressure within the base cylinder. Negative pressure draws liquid into the pipette tip, while positive pressure expels it, thus achieving the function of aspiration and dissipation. Simultaneously, the piston unit slides a certain distance on the base cylinder, using its displacement to push the pipette tip, thereby retracting it. Based on this, an air pump is replaced, eliminating the need for an air pump and related tubing, as well as a separate pipette tip retraction structure, effectively reducing costs and space requirements. Attached Figure Description

[0046] To more clearly illustrate the technical solutions of the exemplary embodiments of the present invention, the accompanying drawings used in the embodiments will be briefly described below. It should be understood that the following drawings only show some embodiments of the present invention and should not be considered as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort. In the drawings:

[0047] Figure 1 This is a schematic diagram of a fully automated chemiluminescence analyzer.

[0048] Figure 2 This is a schematic diagram of the storage area and the feed channel.

[0049] Figure 3 This is a schematic diagram of the second feed unit.

[0050] Figure 4 This is a structural diagram of the pusher component.

[0051] Figure 5 This is a schematic diagram of the reaction vessel.

[0052] Figure 6 This is a structural schematic diagram of the positioning component.

[0053] Figure 7 This is a schematic diagram of the pipette module.

[0054] Figure 8 This is a schematic diagram of a pipette.

[0055] Figure 9 This is a schematic diagram of the sample reagent module.

[0056] Figure 10 This is a structural diagram of the suction head storage module.

[0057] The attached diagram shows the markings and corresponding component names:

[0058] 1. Frame; 101. Storage area; 102. Feed channel; 103. Guide plate; 104. Cover plate; 105. Positioning rod; 106. Positioning spring; 2. Feed module; 21. First feed unit; 22. Second feed unit; 201. Drive motor; 202. Synchronous belt; 203. Transmission plate; 204. Pusher; 205. Base plate; 206. Base rod; 207. Push plate; 208. Limiting rod; 209. Torsion spring; 3. 31. Pipette Module; 32. Triaxial Module; 301. Pipette; 302. X-axis Module; 303. Z-axis Module; 304. Addition Plate; 305. Driver; 306. Base Cylinder; 307. Pipette Tip; 308. Piston Unit; 309. Piston Head; 310. Piston Rod; 311. Guide Shaft; 312. Pipette Tip Push Plate; 313. Baffle; 314. Spring; 315. Position Monitor; 4. Sample Reagent Module; 4 01. Lower base plate; 402. Storage plate; 403. Mixing mechanism; 404. Reagent position; 405. Sample position; 406. Mixing motor; 407. Placement box; 408. Placement slot; 5. Pipe tip storage module; 501. Base; 502. Spare pipette tip; 6. Reaction cup; 601. Base; 602. Cup body; 603. Additional fixing bracket; 604. Guide groove; 605. Guide surface; 606. Positioning groove; 7. Working station; 701. 702. Sample addition position; 703. Reagent addition position; 704. Substrate mixing position; 705. Detection position; 8. Experimental equipment; 810. Liquid extraction unit; 811. First motor; 812. First intermediate plate; 813. Liquid extraction needle; 820. Detection unit; 821. Second motor; 822. Second intermediate plate; 823. Detector; 830. Mixing unit; 831. Third motor; 832. Driving gear; 833. Passive rack; 834. Magnetic part. Detailed Implementation

[0059] To make the objectives, technical solutions, and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the embodiments and accompanying drawings. The illustrative embodiments and descriptions of the present invention are only used to explain the present invention and are not intended to limit the present invention.

[0060] In the following description, numerous specific details are set forth in order to provide a thorough understanding of the invention. However, it will be apparent to those skilled in the art that these specific details are not necessary to practice the invention. In other embodiments, well-known structures, circuits, materials, or methods have not been specifically described in order to avoid obscuring the invention.

[0061] Throughout this specification, references to "an embodiment," "an example," or "an example" mean that a particular feature, structure, or characteristic described in connection with that embodiment or example is included in at least one embodiment of the invention. Therefore, the phrases "an embodiment," "an example," "an example," or "an example" appearing in various places throughout the specification do not necessarily refer to the same embodiment or example. Furthermore, specific features, structures, or characteristics can be combined in one or more embodiments or examples in any suitable combination and / or sub-combination. Moreover, those skilled in the art will understand that the illustrations provided herein are for illustrative purposes and are not necessarily drawn to scale. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0062] In the description of this invention, the terms "front", "rear", "left", "right", "up", "down", "vertical", "horizontal", "high", "low", "inner", and "outer" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting the scope of protection of this invention.

[0063] Example 1:

[0064] like Figures 1-10 As shown, a fully automated chemiluminescence analyzer includes a frame 1, a feeding module 2, a pipette module 3, a sample reagent module 4, and a pipette tip storage module 5;

[0065] The frame 1 has a worktable, on which there are interconnected storage areas 101 and feed channels 102. The storage area 101 is used to store reaction cups 6, and the feed channel 102 is provided with several workstations 7 and test equipment 8 located at the corresponding workstations 7.

[0066] The cup feeding module is used to push the reaction cup 6 so that the reaction cup 6 enters the feed channel 102 from the storage area 101 and passes through each station 7 in sequence along the feed channel 102;

[0067] The pipette module 3, the sample and reagent module 4, and the pipette tip storage module 5 are respectively mounted on the rack 1. The pipette module 3 is used to aspirate and displace liquid from the reaction cup 6, the sample and reagent module 4 is used to place samples and reagents, and the pipette tip storage module 5 is used to store pipette tips 307.

[0068] In the fully automated chemiluminescence analyzer, the frame 1 provides installation space for other functional modules, so that the feeding module 2, pipette module 3, sample reagent module 4, pipette tip storage module 5 and related test equipment 8 can be integrated on the frame 1. This achieves miniaturization while completing the test, making the fully automated chemiluminescence analyzer compact in structure, more economical, and helping to reduce economic costs.

[0069] Specifically, the frame 1 has a basic shape and size, and the worktable is provided with a storage area 101 and a feed channel 102. The storage area 101 contains several reaction cups 6, thereby providing materials for batch testing. The feed channel 102 is used to guide the movement of the reaction cups 6 so that the reaction cups 6 pass through each station 7 in sequence, and at the corresponding station 7, they cooperate with the corresponding testing equipment 8 to complete the corresponding operation.

[0070] The feed module 2 is used to push the reaction cup 6, causing it to move along the path of the storage area 101 and the feed channel 102, thereby completing the experiment. The pipette module 3 is used to aspirate and displace liquid, thereby injecting the liquid from the sample reagent module 4 into the reaction cup 6. It is easy to understand that the liquid should be injected in sequence according to the experimental requirements to ensure the accuracy of the experimental results. Furthermore, the pipette module 3 can also achieve liquid mixing by aspirating and displacing air.

[0071] The sample reagent module 4 is used to hold samples and reagents; the specific liquid type is selected by those skilled in the art according to the experimental requirements. The pipette tip storage module 5 provides pipette tips 307 for the pipette module 3, preventing liquid contamination and helping to improve the accuracy of the experiment. The experimental equipment 8 is used to perform the operations required at the corresponding workstation 7 to ensure that the experiment can proceed smoothly.

[0072] During operation, the operator places an appropriate amount of reaction cup 6 into storage area 101, adds the corresponding sample and reagents into sample and reagent module 4, and places an appropriate amount of pipette tip 307 into pipette tip storage module 5. Then, the fully automated chemiluminescence analyzer is started. After the fully automated chemiluminescence analyzer is started, feed module 2 pushes reaction cup 6 along storage area 101 to feed channel 102, and then pushes reaction cup 6 along feed channel 102 sequentially through each station 7. After reaction cup 6 reaches the corresponding station 7, it pauses and waits for pipette module 3 and / or experimental equipment 8 to perform their work. It then moves again after the work is completed, or it may pause for a period of time before moving, depending on the experimental requirements.

[0073] During the experiment, the pipette module 3 transfers the sample reagent module 4 into the reaction cup 6. After each operation, the pipette module 3 must remove the pipette tip 307 and install a new pipette tip 307 from the pipette tip storage module 5 to avoid liquid contamination. Similarly, the experimental equipment 8 performs the corresponding operations.

[0074] Example 2:

[0075] This embodiment, based on Embodiment 1, introduces a fully automated chemiluminescence analyzer, specifically: as follows: Figures 1-4 As shown, in the fully automated chemiluminescence analyzer, the feed module 2 includes a first feed unit 21 located in the storage area 101 and a second feed unit 22 located in the feed channel 102;

[0076] Both the first feed unit 21 and the second feed unit 22 include a drive motor 201, a synchronous belt 202, a transmission plate 203, and a pusher 204. The output end of the drive motor 201 is connected to the synchronous belt 202, which is parallel to the storage area 101 or the feed channel 102. The transmission plate 203 connects the synchronous belt 202 and the pusher 204 so that the pusher 204 moves along the storage area 101 or the feed channel 102.

[0077] Accordingly, the first feed unit 21 includes two pushers 204 respectively disposed on both sides of the storage area 101 and facing each other, and the second feed unit 22 includes a plurality of pushers 204 spaced apart along the length of the transmission plate 203.

[0078] Based on the above design, the structures of the first feeding unit 21 and the second feeding unit 22 are basically the same. The difference lies in the arrangement of the pushers 204. Specifically, for the first feeding unit 21, two opposing pushers 204 enable the reaction cup 6 to move synchronously as a whole, allowing the reaction cup 6 to enter the transition section quickly and accurately, preventing the reaction cup 6 from getting stuck. For the second feeding unit 22, multiple pushers 204 arranged in the same direction increase the contact points with a single reaction cup 6, improving the pushing efficiency and the smoothness of the reaction cup 6's movement. It also facilitates contact with and pushing multiple reaction cups 6, allowing multiple reaction cups 6 to be placed in the feeding channel 102 simultaneously, thus improving the detection efficiency.

[0079] Correspondingly, the structure of the transmission plate 203 also differs. Specifically, for the first feed unit 21, the transmission plate 203 extends from one side of the storage area 101 to the other side, while also avoiding surrounding components. Therefore, the transmission plate 203 in the first feed unit 21 can be constructed as any suitable irregular shape. For the second feed unit 22, any suitable strip plate can be selected for the transmission plate 203.

[0080] It is easy to understand that the drive motor 201 and the synchronous belt 202 can be any suitable existing model.

[0081] In one possible implementation, at least one second feed unit 22 is provided on the feed channel 102, and when multiple second feed units 22 are provided, the multiple second feed units 22 are arranged sequentially along the feed channel 102.

[0082] Based on the above design scheme, depending on the testing requirements, such as fewer testing steps and a smaller number of testing devices, only one second feed unit 22 is needed, and correspondingly, the length of the feed channel 102 is also shorter. Conversely, if there are more testing steps and a larger number of testing devices, multiple second feed units 22 can be set up, which can meet the requirement of pushing the reaction cup 6 and avoid the size of a single second feed unit 22 being too large. In other words, the second feed unit 22 is constructed as a standard part, and an appropriate number of second feed units 22 can be selected according to the actual testing requirements.

[0083] In one possible implementation, the distance between the outermost pusher 204 at one end of two adjacent second feed units 22 is less than the length of the reaction cup 6.

[0084] Based on the above design scheme, when multiple second feed units 22 are provided, by limiting the spacing of the pushers 204, the reaction cup 6 can simultaneously contact the pushers 204 of two adjacent second feed units 22. When the same reaction cup 6 is located between two adjacent second feed units 22, both adjacent second feed units 22 can push the reaction cup 6 to move through the pushers 204, reducing the load pressure of a single second feed unit 22 and helping to improve the service life of the second feed unit 22.

[0085] In one possible implementation, the pusher component 204 includes a base plate 205, a base rod 206, a push plate 207, and a limiting rod 208.

[0086] The base plate 205 is used to connect the transmission plate 203, and the base rod 206 is disposed on the base plate 205;

[0087] One end of the push plate 207 is configured as a rotating end that is rotatably mounted on the base rod 206 via a torsion spring 209, and the other end of the push plate 207 is configured as a pushing end that extends to the outside of the base plate 205. Along the pushing direction, the push plate 207 gradually tilts from the rotating end to the pushing end. Accordingly, the push plate 207 can rotate around the base rod 206 as the center.

[0088] The limiting rod 208 is disposed on the base plate 205 and located on the side of the push plate 207. Along the pushing direction, the limiting rod 208 is located downstream of the push plate 207. Accordingly, the limiting rod 208 is used to limit the range of rotation of the push plate 207.

[0089] Based on the above design, the base plate 205 is used to connect the transmission plate 203 and provide installation space for other components, thereby enabling the linkage of other components. The base rod 206 is used to connect the base plate 205 and the push plate 207, and also provides a rotation center for the push plate 207. The push plate 207 is used to contact and push the reaction cup 6, so that the reaction cup 6 moves.

[0090] The pusher plate 207 tilts and abuts against the reaction cup 6, thereby pushing the reaction cup 6 to move along the feed channel 102. Along the pushing direction, i.e., the forward direction of the reaction cup 6, since the limiting rod 208 is located downstream of the pusher plate 207, after the pushing end of the pusher plate 207 abuts against the reaction cup 6, the pusher plate 207 rotates forward and abuts against the limiting rod 208, thus allowing the pusher plate 207 to stably transmit driving force, thereby pushing the reaction cup 6 forward. Furthermore, the pusher plate 207 abuts against the limiting rod 208, thereby eliminating the forward rotation of the pusher plate 207 when the reaction cup 6 moves forward, avoiding collisions and vibrations caused by forward rotation.

[0091] After the pusher plate 207 moves a certain distance, it needs to return to its initial position. During the retraction of the pusher component 204, the pusher plate 207 will rotate in the opposite direction due to its contact with the reaction cup 6. Since the limit rod 208 is located downstream of the pusher plate 207, the reverse rotation of the pusher plate 207 is not restricted. The reverse rotation of the pusher plate 207 is used to avoid collision and prevent the pusher plate 207 from causing the reaction cup 6 to move backward during the retraction process.

[0092] In addition, the push plate 207 is connected to the base rod 206 via a torsion spring 209. Regardless of whether it rotates in the forward or reverse direction, the push plate 207 can be reset via the torsion spring 209 to ensure that the push plate 207 is in the designed position.

[0093] Example 3:

[0094] This embodiment, based on the above embodiments, introduces a fully automated chemiluminescence analyzer, specifically: as follows: Figure 1 , Figure 2 , Figure 5 and Figure 6 As shown, in the fully automated chemiluminescence analyzer, a guide plate 103 is provided on both sides of the storage area 101, and correspondingly, a matching guide groove 604 is provided at both ends of the reaction cup 6.

[0095] The feed channel 102 is provided with a cover plate 104, and the cover plate 104 is provided with several through holes. Correspondingly, each through hole corresponds to a station 7.

[0096] The feed channel 102 is provided with a number of spaced positioning elements, including a positioning rod 105 and a positioning spring 106. One end of the positioning rod 105 extends into the feed channel 102 and can be inserted into the positioning groove 606. The other end of the positioning rod 105 is connected to the feed channel 102 through the positioning spring 106. Correspondingly, the side of the reaction cup 6 is provided with a positioning groove 606 adapted to the positioning rod 105, and the contact surfaces of the positioning rod 105 and the positioning groove 606 are both constructed as arc surfaces.

[0097] Based on the above design scheme, for the storage area 101, two guide plates 103 cooperate with each other to clamp the two ends of the reaction cup 6, realize connection and guidance, so that the reaction cup 6 moves stably and synchronously within the storage area 101, effectively preventing the reaction cup 6 from tipping over.

[0098] For the feed channel 102, the cover plate 104 is used to prevent the reaction cup 6 from tilting up when moving, so that the reaction cup 6 can move more smoothly. At the same time, it can also minimize the risk of the material conveyed by the test equipment 8 falling into the feed channel 102, thereby protecting the feed channel 102. In addition, the cover plate 104 is flatter and easier to clean.

[0099] For the second feed unit 22, it is reset by retracting the pusher 204, thereby pushing the reaction cup 6 again. When the pusher 204 retracts, the pusher plate 207 rotates in the opposite direction to avoid the reaction cup 6. However, due to the torsion spring 209, the pushing end of the pusher plate 207 still abuts against the outer wall of the base 601, posing a risk of the reaction cup 6 being pulled back. By cooperating with the positioning groove 606 and the positioning rod 105, when the positioning rod 105 is inserted into the positioning groove 606, the position of the reaction cup 6 is fixed, effectively solving the problem of the reaction cup 6 being pulled back.

[0100] Furthermore, in the feed channel 102, the moving position of the reaction cup 6 must be accurately stopped at the corresponding station 7 to facilitate related operations. By setting the positioning element at the corresponding station 7, when the cup body 602 moves to the adjacent station 7, the positioning rod 105 is inserted into the corresponding positioning groove 606, increasing the resistance to the forward movement of the reaction cup 6, and the second feed unit 22 pauses, so that the reaction cup 6 stops at the corresponding station 7. Accordingly, the positioning groove 606 corresponds one-to-one with the cup body 602, and the position of the cup body 602 is reflected through the positioning groove 606, so that the cup body 602 can accurately stop at the corresponding station 7.

[0101] After the relevant work is completed, the second feed unit 22 is restarted and the power of the drive motor 201 is appropriately increased so that the positioning rod 105 retracts into the feed channel 102, ensuring that the pusher 204 moves the reaction cup 6 so that the positioning groove disengages from the positioning rod 105. When the next positioning groove 606 aligns with the positioning rod 105, the positioning rod 105 extends outward under the push of the positioning spring 106 and inserts into the positioning groove 606, so that the second feed unit 22 pauses and the reaction cup 6 stops at the work station 7 again.

[0102] For storage area 101, the retraction of reaction cup 6 has no impact on detection, so no positioning device is needed in storage area 101.

[0103] In one possible implementation, the storage area 101 and the sample reagent module 4 are spaced apart. Correspondingly, a feed channel 102 and a pipette tip storage module 5 are respectively provided on both sides of the storage area 101 and the sample reagent module 4. The storage area 101 is vertical and connected to the end of the feed channel 102. Based on the above design, that is, the storage area 101 and the sample reagent module 4 are located in the same area, with the feed channel 102 and the pipette tip storage module 5 respectively provided on both sides of this area, the space of the workbench is fully utilized, which helps to reduce the size of the fully automated chemiluminescence analyzer.

[0104] Example 4:

[0105] This embodiment, based on the above embodiments, introduces a fully automated chemiluminescence analyzer, specifically: as follows: Figure 1 , Figure 2 , Figure 5 and Figure 6 As shown, in the fully automated chemiluminescence analyzer, a reaction cup 6 is placed on the worktable. The reaction cup 6 includes a base 601 and a cup body 602. The base 601 is provided with a number of spaced insertion holes, and the cup body 602 is provided with a number of insertion holes, which are respectively inserted into the insertion holes. Correspondingly, the base 601 is provided with an additional fixing bracket 603 located above the insertion holes. The fixing bracket is provided with a number of fixing holes. The insertion holes, fixing holes and cup body 602 are arranged in a one-to-one correspondence.

[0106] Correspondingly, the guide groove 604 is located on the outer wall surface at both ends of the base 601, and the positioning groove 606 is provided in several places and spaced apart on the side of the base 601. The base 601 is also provided with guide surfaces 605 at both ends, and there are two guide surfaces 605 respectively located on the upper and lower sides of the guide groove 604.

[0107] Based on the above design, in the reaction cup 6, the base 601 cooperates with the cup body 602 through the insertion hole and the additional fixing bracket 603, increasing the contact points with the cup body 602 to improve the stability of the overall structure. The cup body 602 is used to contain various materials, and the reaction cup 6 includes multiple cup bodies 602 to improve the efficiency of the experiment; as for the specific number of cup bodies 602, optionally, four cup bodies 602 are provided on the base 601, or, those skilled in the art can select according to specific circumstances.

[0108] The base 601 is connected to the storage area 101 via a guide groove 604. For the feed channel 102, the base 601 has a suitable guide surface 605. The guide surface 605 reduces the resistance to the forward movement of the reaction cup 6, improves the pushing efficiency of the second feed unit 22, and reduces the pushing load on the second push unit. Correspondingly, the base 601 uses a positioning groove 606 to engage with a positioning element to fix and position the reaction cup 6, improving the accuracy of the reaction cup 6's alignment with the work station 7 and preventing the reaction cup 6 from shifting backward when the second feed unit 22 retracts.

[0109] Example 5:

[0110] This embodiment, based on the above embodiments, introduces a fully automated chemiluminescence analyzer, specifically: as follows: Figure 1 , Figure 7 and Figure 8 As shown, in the fully automated chemiluminescence analyzer, the pipette module 3 includes a triaxial module 31 and a pipette 32;

[0111] The three-axis module 31 includes an X-axis module 301, a Y-axis module 302 and a Z-axis module 303 connected in sequence. The Z-axis module 303 is connected to the pipette 32 through an auxiliary plate 304.

[0112] The pipette 32 includes a base cylinder 306, a pipette tip 307, and a piston unit 308. The base cylinder 306 is detachably connected to the pipette tip 307 via a gourd head 309. The piston unit 308 is reciprocally slidably disposed on the base cylinder 306. The piston unit 308 is used for the pipette tip 307 to aspirate and dissipate liquid and to retract the pipette tip 307. Correspondingly, the gourd head 309 is provided with an intermediate hole for connecting the base cylinder 306 and the pipette tip 307.

[0113] Accordingly, the auxiliary plate 304 is provided with a driver 305 for driving the piston rod 310 to slide back and forth along the base cylinder 306.

[0114] In the pipette module 3, the pipette 32 is moved by the three-axis module 31 to move the pipette 32 to the required position, thereby performing operations such as aspiration and dissipation of liquid, withdrawal of pipette tip 307, and attachment of pipette tip 307, thus achieving fully automatic operation; the three-axis module 31 includes an X-axis module 301, a Y-axis module 302 and a Z-axis module 303. When the pipette 32 is moved, at least one of the X-axis module 301, the Y-axis module 302 and the Z-axis module 303 is activated and moves the pipette 32.

[0115] Furthermore, the actuator 305 provides power to drive the piston rod 310 to slide, avoiding manual operation and reducing human intervention, thus helping to improve the automation level and operational accuracy of the pipetting module. Optionally, the actuator 305 can be a lead screw motor or any other suitable existing motor.

[0116] In the pipette 32, the piston unit 308 enables the functions of aspirating / discharging liquid and retracting the pipette tip 307. Specifically, the piston unit 308 is slidably mounted on the base cylinder 306. During the reciprocating sliding of the piston unit 308, the volume of the base cylinder 306 changes. When the pipette tip 307 is inserted below the liquid surface, the base cylinder 306 cannot exchange gas with the outside environment through the pipette tip 307. Therefore, the reciprocating sliding of the piston unit 308 creates a negative or positive pressure within the base cylinder 306. Negative pressure draws liquid into the pipette tip 307, while positive pressure dissipates the liquid from the pipette tip 307. Based on this, the reciprocating sliding of the piston unit 308 achieves the function of aspirating / discharging liquid. Correspondingly, this replaces the need for an air pump, eliminating the need for an air pump and related tubing, effectively reducing costs and space requirements, and eliminating concerns about accuracy issues caused by tubing clamping.

[0117] As is easily understood, the piston unit 308 is reciprocatingly slidably mounted on the base cylinder 306. This means the piston unit 308 will slide a certain distance on the base cylinder 306, and the displacement of the piston unit 308 will push the suction head 307, thereby achieving the suction head retraction operation. Based on this, the suction head retraction structure is replaced, effectively reducing costs and space occupation.

[0118] Furthermore, since the liquid suction / dissipation and the suction head retraction 307 are independent and do not interact, the sliding area of ​​the piston unit 308 on the base cylinder 306 is divided into two or three sections. One section is used for liquid suction / dissipation, and the other section is used for suction head retraction 307. A transition section may be provided if necessary. Thus, by restricting the physical position, the piston unit 308 is prevented from retracting the suction head 307 during liquid suction / dissipation, ensuring the smooth progress of the experiment.

[0119] In one possible implementation, the base cylinder 306 is constructed as a cylindrical structure with open ends. One end of the base cylinder 306 is connected to the piston unit 308, and the other end of the base cylinder 306 is provided with a gourd head 309. The gourd head 309 is inserted into the base cylinder 306 and extends outward. The suction head 307 is detachably connected to the extended end of the gourd head 309. The gourd head 309 is provided with an intermediate hole for connecting the base cylinder 306 and the suction head 307.

[0120] Based on the above design, the base cylinder 306 connects the piston unit 308 and the gourd head 309 through an open structure. The gourd head 309 is used to connect to the suction head 307. It is easy to understand that the diameter of at least the outer end of the gourd head 309 is adapted to the suction head 307 to achieve the connection between the gourd head 309 and the suction head 307. Furthermore, the gourd head 309 is connected through a central hole, ensuring that pressure changes caused by the sliding of the piston unit 308 can be transmitted to the suction head 307, thereby achieving the function of suction and discharge of liquid.

[0121] When the gourd head 309 is inserted into the suction head 307, the two are connected through frictional resistance. Preferably, the diameter of the gourd head 309's extended end is slightly larger than the inner diameter of the suction head 307. When the two are connected, the suction head 307 can deform and clamp the gourd head 309 to improve the stability of the connection. Generally, the diameter of the gourd head 309's extended end is at least 2 mm larger than the inner diameter of the suction head 307. As for the specific value, those skilled in the art can select it according to the actual situation.

[0122] For the sealing ring, any suitable existing model can be selected.

[0123] In one possible implementation, the gourd head 309 is shaped like a shaft, and the two ends of the gourd head 309 are respectively configured as a first connecting end adapted to the base cylinder 306 and a second connecting end adapted to the suction head 307. The first connecting end is connected to the base cylinder 306 through a sealing ring, and the second connecting end is configured as an enlarged head.

[0124] Based on the above design, the first connecting end is connected and sealed by a sealing ring to avoid gaps that could affect the operation of the piston unit 308. The second connecting end is connected to the suction head 307 via an enlarged head. The enlarged head achieves connection while also increasing the size of the suction head, preventing an overall increase in the diameter of the suction head 309. It is easy to understand that the enlarged head can be constructed into any suitable shape.

[0125] In one possible implementation, the piston unit 308 includes a piston rod 310, a guide shaft 311, and a suction head pusher plate 312.

[0126] The piston rod 310 passes through the base cylinder 306 and can slide back and forth along the base cylinder 306. The piston rod 310 is arranged opposite to the hoist head 309. Correspondingly, one end of the base cylinder 306 is closed by the piston rod 310, and the other end is connected to the outside through the middle hole on the hoist head 309.

[0127] The guide shaft 311 passes through the base cylinder 306 and is parallel to the axis of the base cylinder 306. The two ends of the guide shaft 311 are respectively connected to the piston rod 310 and the suction head push plate 312. Correspondingly, the base cylinder 306 is provided with mounting holes adapted to the guide shaft 311.

[0128] The suction head push plate 312 is fitted onto the gourd head 309 and can slide back and forth along the gourd head 309.

[0129] Based on the above design, the piston rod 310 is reciprocatingly slidably mounted on the base cylinder 306. The sliding of the piston rod 310 will cause a change in the volume of the base cylinder 306, specifically a change in the volume of the part from the suction head 307 to the end face of the piston rod 310. When the suction head 307 is inserted below the liquid surface, the gas in the base cylinder 306 is blocked by the liquid and cannot be discharged. The reciprocating sliding of the piston rod 310 will create a negative pressure or a positive pressure, thereby sucking up and discharging the liquid.

[0130] The piston rod 310 performs liquid suction and discharge operations, but the piston rod 310 is positioned opposite the pipette tip 307, and due to the obstruction of the gourd head 309, the piston rod 310 cannot directly contact the pipette tip 307. Therefore, to achieve the function of retracting the pipette tip 307, the piston unit 308 also includes a guide shaft 311 and a pipette tip pusher plate 312. The pipette tip pusher plate 312 is sleeved on the gourd head 309, which reduces the distance from the pipette tip 307, helping to reduce the volume of the pipette needle 32. On the other hand, it is positioned on the same side as the pipette tip 307 so as to contact and push the pipette tip 307. The guide shaft 311 is used to connect the piston rod 310 and the pipette tip pusher plate 312, thereby realizing the linkage between the piston rod 310 and the pipette tip pusher plate 312, so that the pipette tip pusher plate 312 moves with the piston rod 310, thereby realizing the retraction of the pipette tip 307.

[0131] As is easily understood, the piston rod 310 is connected to the base cylinder 306 through a sealing ring. Based on this, a sliding seal is achieved through the sealing ring, ensuring that the piston rod 310 can slide and preventing gaps from appearing.

[0132] Optionally, the piston rod 310 is provided with a baffle 313, and the suction head push plate 312 includes a suction retraction part sleeved on the hoist head 309 and a baffle part connected to the suction retraction part. The two ends of the guide shaft 311 are detachably connected to the baffle 313 and the baffle part by screws. Based on the above design, the piston rod 310 expands its volume through the baffle 313, thereby facilitating the connection of the guide shaft 311. Similarly, the suction head push plate 312 is connected to the guide shaft 311 through the baffle part. Furthermore, the guide shaft 311 is connected in a detachable manner for easy disassembly and assembly, and also for convenient later inspection and maintenance.

[0133] Optionally, at least two guide shafts 311 are provided and evenly distributed on the base cylinder 306, and each guide shaft 311 is fitted with a spring 314, which is located in the mounting hole. Based on the above design, the multiple guide shafts 311 cooperate with each other to make the suction tip pusher plate 312 move synchronously, avoiding skewness and jamming during the movement of the suction tip pusher plate 312 and ensuring the smooth movement of the suction tip pusher plate 312. The spring 314 is used for the reset of the guide shafts 311, so that the piston unit 308 automatically resets after completing the relevant operation, improving the automation level of the pipette needle 32.

[0134] The pipette 32 has requirements for the sliding area of ​​the piston unit 308, that is, the sliding area on the base cylinder 306 of the piston unit 308 is segmented, combined with... Figure 8 To elaborate further, the area near the upper end of the base cylinder 306 is used for the operation of retracting the suction head 307, and the area above this is used for liquid suction and discharge operations. In order to improve the accuracy of the operation, the position of the piston rod 310 is monitored by the position monitor 315. At the same time, the position monitor 315 can also transmit status information, such as taking the suction head 307 and retracting the suction head 307, so that the staff can keep track of real-time work information.

[0135] Optionally, the position monitor 315 includes at least one photoelectric sensor, which is mounted on the auxiliary plate 304 or the base cylinder 306. The working end of the photoelectric sensor faces the piston rod 310. Correspondingly, the baffle 313 is selected to be a photoelectric baffle 313 adapted to the photoelectric sensor.

[0136] Based on the above design, the piston rod 310 will slide back and forth during operation. By cooperating with the photoelectric baffle 313 and the photoelectric sensor, the position change of the piston rod 310 can be monitored. The guide shaft 311 and the suction head push plate 312 move synchronously with the piston rod 310, thus realizing the monitoring of the overall position of the piston unit 308.

[0137] Furthermore, for the piston unit 308, at least one photoelectric sensor is required to monitor whether the suction head 307 retraction operation is completed, that is, to ensure that the sliding distance of the piston rod 310 is long enough so that the suction head pusher plate 312 can push the suction head 307 to separate from the gourd head 309. The photoelectric sensor can also measure distance, and thus can be used to monitor the section where the piston rod 310 is located.

[0138] Optionally, multiple photoelectric sensors can be set, each monitoring a different position. The position of the piston unit 308 can be determined by whether the photoelectric baffle 313 blocks the corresponding photoelectric sensor.

[0139] It is easy to understand that any suitable existing model of photoelectric sensor can be selected.

[0140] Optionally, position sensors are provided on the X-axis module 301, Y-axis module 302, and Z-axis module 303 respectively. Based on the above design, the position sensors monitor the movement distance of the corresponding modules to avoid collisions at the module ends, ensuring that the liquid in the suction head 307 will not drip due to collisions, while also protecting the three modules and improving the service life of the triaxial module 31.

[0141] Example 6:

[0142] This embodiment, based on the above embodiments, introduces a fully automated chemiluminescence analyzer, specifically: as follows: Figure 1and Figure 9 As shown, in the fully automated chemiluminescence analyzer, the sample reagent module 4 includes a lower base plate 401, a storage plate 402, and a mixing mechanism 403;

[0143] The lower plate 401 is detachably connected to the storage plate 402, and one end of the lower plate 401 is connected to the mixing mechanism 403; the storage plate 402 is provided with at least one reagent position 404 and at least one sample position 405.

[0144] The mixing mechanism 403 includes a mixing motor 406 and a placement box 407 connected to the lower base plate 401. The mixing motor 406 is fixed on the bottom surface of the lower base plate 401, and the placement box 407 is disposed on the top surface of the lower base plate 401. The output end of the mixing motor 406 passes through the lower base plate 401 and is connected to the placement box 407. Correspondingly, the placement box 407 is provided with a placement slot 408 adapted to the reagent kit, and the storage plate 402 is provided with an inner groove adapted to the placement box 407.

[0145] Based on the above design, the lower plate 401 has a basic shape and thickness. The storage plate 402 stores the reagents and samples used in the experiment through the reagent compartment 404 and the sample compartment 405, respectively. The storage plate 402 is detachably connected to the lower plate 401, so if necessary, it can be removed and placed in a refrigerator. The mixing mechanism 403 is used for liquid mixing, which helps to improve experimental efficiency, ensure experimental accuracy, and enhance experimental stability.

[0146] Based on the structure of the mixing mechanism 403, the liquid to be mixed is placed into the placement tank 408. The mixing motor 406 is started, which drives the placement box 407 to rotate. To save space, the placement box 407 is located in the inner groove of the storage plate 402. To prevent the placement box 407 from hitting the storage plate 402, the mixing motor 406 drives the placement box 407 to swing back and forth. After swinging for a period of time, the liquid is mixed evenly before being transferred.

[0147] Example 7:

[0148] This embodiment, based on the above embodiments, introduces a fully automated chemiluminescence analyzer, specifically: as follows: Figures 1-3 As shown, in the fully automated chemiluminescence analyzer, the experimental device 8 includes a liquid extraction unit 810 for waste liquid discharge, a detection unit 820 for sample detection, and a mixing unit 830 for liquid mixing.

[0149] The feed channel 102 is provided with a heating film laid along the feed channel 102, a temperature sensor for monitoring the temperature of the feed channel 102, and an overheat protector for preventing overheating. The heating film, temperature sensor, and overheat protector are electrically connected and form a heating unit.

[0150] Based on the above design, the liquid extraction unit 810 is used to extract excess liquid from the reaction vessel 6, achieving waste liquid discharge. The detection unit 820 is used to detect the test results. The mixing unit 830 is used to mix the liquid to improve test efficiency, ensure test accuracy, and improve test stability. Simultaneously, it works in conjunction with the mixing mechanism 403 in the sample reagent module 4 to achieve multiple mixing operations, ensuring the mixing effect. Furthermore, the mixing unit 830 is used for mixing after liquid is added to the reaction vessel 6, and the mixing mechanism 403 is used for mixing when the liquid is placed on the storage plate 402.

[0151] Meanwhile, a heating film is installed on the feed channel 102 to achieve heating. During the movement of the reaction vessel 6, the temperature of the reaction vessel 6 is maintained within the designed test temperature range, making the test results more accurate. For the heating film, the real-time temperature is monitored by a temperature sensor, and the temperature is controlled by an overheat protector to ensure that the temperature of the reaction vessel 6 is kept within the designed test temperature range.

[0152] In one possible implementation, the liquid extraction unit 810 includes a first motor 811, a first intermediate plate 812 and a liquid extraction needle 813. The first motor 811 is connected to the first intermediate plate 812 via a threaded rod. The first intermediate plate 812 is connected to the liquid extraction needle 813 and can move along the threaded rod. The liquid extraction needle 813 is disposed on the first intermediate plate 812 and is located above one of the workstations 7.

[0153] The detection unit 820 includes a second motor 821, a second intermediate plate 822 and a detector 823. The second motor 821 is connected to the second intermediate plate 822 through a threaded rod. The second intermediate plate 822 is connected to the detector 823 and can move along the threaded rod. The liquid extraction needle 813 is disposed on the second intermediate plate 822 and located above one of the workstations 7.

[0154] Based on the above design, the structures of the liquid extraction unit 810 and the detection unit 820 are basically the same. Taking the liquid extraction unit 810 as an example, it is powered by the first motor 811 to drive the first intermediate plate 812 to reciprocate up and down along the threaded rod. During liquid extraction, the extraction needle 813 moves and inserts below the liquid surface of the reaction cup 6. At other times, the extraction needle 813 moves away from the reaction cup 6 to avoid obstructing its movement. The functions of the liquid extraction unit 810 and the detection unit 820 are different. The liquid extraction unit 810 extracts liquid through the extraction needle 813, while the detection unit 820 detects liquid through the detector 823.

[0155] As is easily understood, the frame 1 is equipped with a waste discharge pump and a waste discharge pipe. The waste discharge pump is connected to the liquid extraction needle 813 through the waste discharge pipe, thereby realizing the discharge of waste liquid.

[0156] Optionally, the detector 823 is a PMT (photomultiplier tube). The working end of the PMT faces the station 7 and is equipped with a light-guiding lens. The working end of the PMT also has a rubber pad for covering the station 7. Based on the above design, the PMT converts the weak light signal into an electrical signal, thereby achieving spectral analysis. Furthermore, the lens guides the light, enabling detection under low-light conditions and increasing the detection range. Covering the station 7 with the rubber pad reduces the incidence of ambient light, preventing external light sources from affecting the photometric results.

[0157] Furthermore, it is easy to understand that, depending on the experimental requirements, the detector 823 can also be any other suitable detection instrument.

[0158] In one possible implementation, the mixing unit 830 includes a third motor 831, a drive gear 832, a driven rack 833, and a magnetic part 834. The third motor 831 is mounted on the frame 1, and the output shaft of the third motor 831 is connected to the drive gear 832. The drive gear 832 meshes with the driven rack 833. The magnetic part 834 is mounted on the driven rack 833 and located outside the feed channel 102. Correspondingly, a suitable magnetic attraction part is placed inside the reaction cup 6.

[0159] The passive rack 833 can reciprocate under the drive of the active gear 832, so as to drive the magnetic part 834 to move up and down relative to the feed channel 102, so that the magnetic part moves in the reaction cup 6 and mixes the liquid.

[0160] Two passive racks 833 are provided and located on both sides of the active gear 832. Correspondingly, two magnetic parts 834 are provided and located on both sides of the feed channel 102, so that the magnetic attraction part moves back and forth in the reaction cup 6 and mixes the liquid.

[0161] Based on the above design, the third motor 831 provides power and drives the drive gear 832 to rotate. The drive gear 832 drives the driven rack 833 to move linearly, and the magnetic part 834 moves with the driven rack 833. When the magnetic part 834 is close to the feed channel 102, such as when the magnetic part 834 is directly facing the feed channel 102, the magnetic part 834 attracts the magnetic suction part inside the reaction cup 6 by magnetic force. When the magnetic part 834 is far from the feed channel 102, the magnetic suction part will stop under the action of the liquid inside the reaction cup 6 and / or the cup wall. Furthermore, the reciprocating rotation of the drive gear 832 realizes the up-and-down reciprocating movement of the magnetic part 834, realizing multiple movements of the magnetic suction part inside the reaction cup 6, so that the liquid inside the reaction cup 6 is stirred and the liquid is mixed.

[0162] When liquid is discharged through the pumping unit 810, the mixing unit 830 provides magnetic force through the magnetic part 834 to fix the magnetic part, so as to prevent the magnetic part from being discharged when the waste liquid is discharged.

[0163] Furthermore, to improve mixing efficiency, two passive racks 833 and two magnetic parts 834 are provided, located on both sides of the feed channel 102 respectively. Based on this, the two passive racks 833 move in opposite directions, so that the magnetic part is attracted by the magnetic force on both sides, realizing the reciprocating movement of the magnetic part in the reaction cup 6, which improves the stirring effect of the liquid and increases the mixing efficiency of the liquid.

[0164] Preferably, magnetic beads are used for the magnetic suction part to reduce the difficulty of moving the magnetic suction part and improve the efficiency of mixing liquid.

[0165] In addition, for reaction cup 6, liquid can be mixed by repeatedly aspirating or evacuating air using pipette module 3.

[0166] Example 8:

[0167] Based on the above embodiments, this embodiment introduces a fully automated chemiluminescence analyzer. Specifically, station 7 includes a sample addition station 701, a reagent addition station 702, a substrate mixing station 703, and a detection station 704 arranged sequentially and at intervals along the feeding direction of the feed channel 102. The pipette module 3 is used to add samples to the sample addition station 701. Liquid addition seats are respectively provided on the outside of the reagent addition station 702 and the substrate mixing station 703. The liquid extraction unit 810 is located above the substrate mixing station 703, the mixing unit 830 is located below the substrate mixing station 703, and the detection unit 820 is located above the detection station 704 and is parallel to the liquid extraction unit 810.

[0168] Based on the above design scheme, and in conjunction with the specific workstation 7, the placement of the experimental equipment 8 is described. The reaction cup 6 will pass sequentially through the sample addition station 701, reagent addition station 702, substrate mixing station 703, and detection station 704. The pipette module 3 is mainly used to add samples to the sample addition station 701, and can also be used for liquid addition and liquid mixing at other workstations 7 when necessary. The liquid addition seat is used to add the corresponding liquid. The liquid extraction unit 810 and the mixing unit 830 are both located at the substrate mixing station 703 and are set one above the other to make full use of the space. The detection unit 820 is located above the detection station 704 and is used to detect the test results.

[0169] Example 9:

[0170] Based on the above embodiments, this embodiment introduces a fully automated chemiluminescence analyzer. Specifically, in the fully automated chemiluminescence analyzer, the frame 1 is also equipped with a control module. The control module is electrically connected to the feeding module 2, the pipette module 3, and the sample reagent module 4, thereby controlling and coordinating the work of each module, ensuring that each module can work automatically, and realizing the linkage of each module, so that the fully automated chemiluminescence analyzer can work automatically, reducing manual intervention, which can reduce the burden on the staff and reduce the impact of human factors on the test results.

[0171] like Figure 10 As shown, the suction head storage module 5 includes a base 501 and spare suction heads 502. Accordingly, several spare suction heads 502 are provided and evenly distributed on the base 501. Based on this, the base 501 has several holes adapted to the spare suction heads 502. The spare suction heads 502 are inserted into the holes, and each spare suction head 502 corresponds to one of the holes. Preferably, the spare suction heads 502 are evenly distributed in an array on the base 501.

[0172] As is readily understood, in the fully automated chemiluminescence analyzer, for components requiring reciprocating motion, such as the first feed unit 21, the second feed unit 22, the triaxial module 31, the liquid extraction unit 810, and the detection unit 820, sensors are used for distance measurement to ensure motion accuracy. Accordingly, those skilled in the art can select any suitable existing sensor, which will not be elaborated further here.

[0173] The specific embodiments described above further illustrate the purpose, technical solution, and beneficial effects of the present invention. It should be understood that the above description is only a specific embodiment of the present invention and is not intended to limit the scope of protection of the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the scope of protection of the present invention.

Claims

1. A fully automated chemiluminescence analyzer, characterized in that, It includes a frame (1), a feeding module (2), a pipette module (3), a sample reagent module (4), and a pipette tip storage module (5); The frame (1) has a worktable, on which there are interconnected storage areas (101) and feed channels (102). The storage area (101) is used to store reaction cups (6), and the feed channel (102) has several workstations (7) and test equipment (8) located at the corresponding workstations (7). The cup feeding module is used to push the reaction cup (6) so that the reaction cup (6) enters the feed channel (102) from the storage area (101) and passes through each station (7) in sequence along the feed channel (102); The pipette module (3), sample reagent module (4) and pipette tip storage module (5) are respectively set on the rack (1). The pipette module (3) is used to aspirate and displace liquid from the reaction cup (6). The sample reagent module (4) is used to place samples and reagents. The pipette tip storage module (5) is used to store pipette tips (307). The feed module (2) includes a first feed unit (21) located in the storage area (101) and a second feed unit (22) located in the feed channel (102). The first feed unit (21) and the second feed unit (22) both include a drive motor (201), a synchronous belt (202), a transmission plate (203), and a pusher (204). The output end of the drive motor (201) is connected to the synchronous belt (202), and the synchronous belt (202) is parallel to the storage area (101) or the feed channel (102). The transmission plate (203) connects the synchronous belt (202) and the pusher (204) so ​​that the pusher (204) moves along the storage area (101) or the feed channel (102). Accordingly, the first feed unit (21) includes two pushers (204) respectively disposed on both sides of the storage area (101) and opposite to each other, and the second feed unit (22) includes a plurality of pushers (204) spaced apart along the length of the transmission plate (203). A guide plate (103) is provided on each side of the storage area (101), and correspondingly, a matching guide groove (604) is provided at each end of the reaction cup (6). The feed channel (102) is provided with a cover plate (104), and the cover plate (104) is provided with several through holes. Correspondingly, each through hole corresponds to a station (7). The feed channel (102) is provided with a number of spaced positioning elements, including a positioning rod (105) and a positioning spring (106). One end of the positioning rod (105) extends into the feed channel (102) and can be inserted into the positioning groove (606). The other end of the positioning rod (105) is connected to the feed channel (102) through the positioning spring (106). Correspondingly, the side of the reaction cup (6) is provided with a positioning groove (606) adapted to the positioning rod (105), and the contact surfaces of the positioning rod (105) and the positioning groove (606) are both constructed as arc surfaces. The storage area (101) and the sample reagent module (4) are spaced apart. Correspondingly, the storage area (101) and the sample reagent module (4) are respectively provided with a feed channel (102) and a pipette tip storage module (5). The storage area (101) is vertical and connected to the end of the feed channel (102). A reaction cup (6) is placed on the workbench. The reaction cup (6) includes a base (601) and a cup body (602). The base (601) has several spaced insertion holes, and the cup body (602) has several insertion holes that are respectively inserted into the insertion holes. Correspondingly, the base (601) has an additional fixing bracket (603) located above the insertion holes. The fixing bracket has several fixing holes. The insertion holes, fixing holes and cup body (602) are set one-to-one. Correspondingly, the guide groove (604) is located on the outer wall surface at both ends of the base (601), and the positioning groove (606) is provided in several places and is spaced apart on the side of the base (601). The base (601) is also provided with guide surfaces (605) at both ends, and there are two guide surfaces (605) respectively located on the upper and lower sides of the guide groove (604).

2. The fully automated chemiluminescence analyzer according to claim 1, characterized in that, The pusher component (204) includes a base plate (205), a base rod (206), a push plate (207), and a limiting rod (208); The base plate (205) is used to connect the transmission plate (203), and the base rod (206) is disposed on the base plate (205); One end of the push plate (207) is configured as a rotating end that is rotatably mounted on the base rod (206) via a torsion spring (209), and the other end of the push plate (207) is configured as a pushing end that extends to the outside of the base plate (205). Along the pushing direction, the push plate (207) gradually tilts from the rotating end to the pushing end. Accordingly, the push plate (207) can rotate around the base rod (206) as the center. The limiting rod (208) is disposed on the base plate (205) and located on the side of the push plate (207). Along the pushing direction, the limiting rod (208) is located downstream of the push plate (207). Accordingly, the limiting rod (208) is used to limit the range of rotation of the push plate (207).

3. The fully automated chemiluminescence analyzer according to claim 1, characterized in that, The pipette module (3) includes a triaxial module (31) and a pipette (32); The three-axis module (31) includes an X-axis module (301), a Y-axis module (302) and a Z-axis module (303) connected in sequence. The Z-axis module (303) is connected to the pipette (32) via an auxiliary plate (304). The pipette (32) includes a base cylinder (306), a pipette tip (307), and a piston unit (308). The base cylinder (306) is detachably connected to the pipette tip (307) via a gourd head (309). The piston unit (308) is reciprocally slidably disposed on the base cylinder (306). The piston unit (308) is used for the pipette tip (307) to aspirate and dissipate liquid and to retract the pipette tip (307). Correspondingly, the gourd head (309) is provided with an intermediate hole for connecting the base cylinder (306) and the pipette tip (307). Accordingly, the auxiliary plate (304) is provided with a driver (305) for driving the piston rod (310) to slide back and forth along the base cylinder (306). The piston unit (308) includes a piston rod (310), a guide shaft (311), and a suction head push plate (312). The piston rod (310) passes through the base cylinder (306) and can slide back and forth along the base cylinder (306). The piston rod (310) is arranged opposite to the gourd head (309). Correspondingly, one end of the base cylinder (306) is closed by the piston rod (310), and the other end is connected to the outside through the middle hole on the gourd head (309). The guide shaft (311) passes through the base cylinder (306) and is parallel to the axis of the base cylinder (306). The two ends of the guide shaft (311) are connected to the piston rod (310) and the suction head push plate (312), respectively. Correspondingly, the base cylinder (306) is provided with mounting holes adapted to the guide shaft (311). The suction head push plate (312) is sleeved on the gourd head (309) and can slide back and forth along the gourd head (309); The piston rod (310) is provided with a baffle (313), and the suction head push plate (312) includes a suction retraction part sleeved on the gourd head (309) and a baffle part connected to the suction retraction part. The two ends of the guide shaft (311) are detachably connected to the baffle (313) and the baffle part by screws. At least two guide shafts (311) are provided and evenly distributed on the base cylinder (306), and each guide shaft (311) is fitted with a spring (314), which is located in the mounting hole.

4. The fully automated chemiluminescence analyzer according to claim 1 or 3, characterized in that, The sample reagent module (4) includes a lower plate (401), a storage plate (402), and a mixing mechanism (403); The lower plate (401) is detachably connected to the storage plate (402), and one end of the lower plate (401) is connected to the mixing mechanism (403); the storage plate (402) is provided with at least one reagent position (404) and at least one sample position (405). The mixing mechanism (403) includes a mixing motor (406) connected to the lower base plate (401) and a placement box (407). The mixing motor (406) is fixed on the bottom surface of the lower base plate (401), and the placement box (407) is disposed on the top surface of the lower base plate (401). The output end of the mixing motor (406) passes through the lower base plate (401) and is connected to the placement box (407). Correspondingly, the placement box (407) is provided with a placement slot (408) adapted to the reagent kit, and the storage plate (402) is provided with an inner groove adapted to the placement box (407).

5. The fully automated chemiluminescence analyzer according to claim 4, characterized in that, The test equipment (8) includes a liquid extraction unit (810) for waste liquid discharge, a detection unit (820) for sample detection, and a mixing unit (830) for liquid mixing. The feed channel (102) is provided with a heating film laid along the feed channel (102), a temperature sensor for monitoring the temperature of the feed channel (102), and an overheat protector for preventing overheating. The heating film, temperature sensor, and overheat protector are electrically connected and form a heating unit.

6. The fully automated chemiluminescence analyzer according to claim 5, characterized in that, The liquid extraction unit (810) includes a first motor (811), a first intermediate plate (812), and a liquid extraction needle (813). The first motor (811) is connected to the first intermediate plate (812) through a threaded rod. The first intermediate plate (812) is connected to the liquid extraction needle (813) and can move along the threaded rod. The liquid extraction needle (813) is disposed on the first intermediate plate (812) and located above one of the workstations (7). The detection unit (820) includes a second motor (821), a second intermediate plate (822) and a detector (823). The second motor (821) is connected to the second intermediate plate (822) via a threaded rod. The second intermediate plate (822) is connected to the detector (823) and can move along the threaded rod. The liquid-drawing needle (813) is set on the second intermediate plate (822) and located above one of the workstations (7).

7. The fully automated chemiluminescence analyzer according to claim 5 or 6, characterized in that, The mixing unit (830) includes a third motor (831), a drive gear (832), a driven rack (833), and a magnetic part (834). The third motor (831) is mounted on the frame (1). The output shaft of the third motor (831) is connected to the drive gear (832). The drive gear (832) meshes with the driven rack (833). The magnetic part (834) is mounted on the driven rack (833) and located outside the feed channel (102). Correspondingly, a suitable magnetic attraction part is placed inside the reaction cup (6). The passive rack (833) can reciprocate under the drive of the active gear (832) to drive the magnetic part (834) to move up and down relative to the feed channel (102) so that the magnetic part moves in the reaction cup (6) and mixes the liquid. Two passive racks (833) are provided and located on both sides of the active gear (832). Correspondingly, two magnetic parts (834) are provided and located on both sides of the feed channel (102) so that the magnetic part moves back and forth in the reaction cup (6) and mixes the liquid.

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