Rhizoma smilacis glabrae series tea substitute drink

By designing the Muhuan series tea-replacement drink, a variety of formulas are provided for patients with different syndromes of gout and spleen deficiency and dampness, the problem of slow treatment in the existing technology has been solved, and the effect of effectively reducing blood uric acid and improving arthritis symptoms is achieved.

CN119586682APending Publication Date: 2025-03-11DONGZHIMEN HOSPITAL OF BEIJING UNIV OF CHINESE MEDICINE
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Patent Information

Application Number
CN202411811875.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-10
Publication Date
2025-03-11

AI Technical Summary

Technical Problem

The prior art has slow effect in the treatment of gout and spleen deficiency and dampness, and requires a more effective health food to assist in the treatment.

Method used

A series of tea-replaced tea drinks in the wild yam series, including drugs such as wild yam, Poria, and Coix seed, providing a variety of composition formulas for patients with different syndromes, and assisting treatment with the effects of strengthening the spleen and removing dampness, unblocking joints, clearing heat and removing dampness, eliminating phlegm and removing blood stasis.

Benefits of technology

This tea drink can effectively reduce blood uric acid levels, improve the symptoms of gout and arthritis, and is suitable for patients with different syndromes, which significantly improves the treatment effect.

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Abstract

The invention discloses a rhizoma smilacis glabrae series tea substitute drink which comprises the following components in parts by mass: 1 part of rhizoma smilacis glabrae, 1 part of poria cocos and 1 part of semen coicis. The rhizoma smilacis glabrae series tea substitute drink can be suitable for patients with different syndromes, all composition medicines in the tea substitute drink are medicine and food homologous medicines or traditional Chinese medicines capable of being used for health-care food, and dialectical conditioning can be carried out on the patients in the hyperuricemia stage and the chronic gouty arthritis stage.
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Description

Technical Field

[0001] The invention relates to the technical field of health-care foods, in particular to a series of smilax glabra tea substitutes. Background Art

[0002] Gout is a disease caused by abnormal uric acid metabolism, which leads to increased uric acid levels in the blood, thus causing urate crystals to deposit in joints or other tissues. The main manifestations are repeated attacks of acute arthritis, chronic arthritis, and uric acid kidney stones. Traditional Chinese medicine believes that gout is based on "spleen deficiency and dampness". In traditional Chinese medicine theory, the spleen is responsible for transportation and transformation, and is responsible for converting nutrients in food into a form that can be used by the human body and helping to eliminate excess water in the body. When the function of the spleen is affected (i.e. spleen deficiency), it may lead to excessive accumulation of moisture in the body (i.e. dampness). This condition may manifest as symptoms such as heaviness, loss of appetite, and loose stools.

[0003] For cases of gout or spleen deficiency and dampness, the following measures are generally taken:

[0004] Dietary adjustments: Avoid high-purine foods (such as animal offal, seafood, etc.), reduce the intake of greasy food, sweets and cold drinks, and eat more easily digestible foods, such as millet porridge, yam and other foods that help to strengthen the spleen and eliminate dampness.

[0005] Moderate exercise: Appropriate physical activity can help improve blood circulation and promote metabolism, but excessive exertion should be avoided.

[0006] Maintain good living habits: ensure adequate rest time and avoid staying up late; control weight and avoid obesity that aggravates the condition.

[0007] However, the above measures are slow to take effect, therefore, it is necessary to design a series of wild yam tea substitutes. Summary of the invention

[0008] In order to overcome the defects in the prior art, a series of tea substitutes made from Chinese smilax glabra is provided.

[0009] The present invention is achieved through the following solutions:

[0010] A series of wild smilax glabra tea substitutes, which include, by weight, 1 part of wild smilax glabra, 1 part of tuckahoe and 1 part of coix seed.

[0011] In terms of mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Prunus quinquefolia, 1 part of Alisma orientalis, 1 part of Phragmites australis, 1 part of Tangerine peel, and 1 part of Plantago seed.

[0012] In terms of mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Imperata cylindrica, 1 part of Lilium, 1 part of Dioscorea macrocephala, and 1 part of Adzuki bean.

[0013] Calculated by mass, the tea substitute also includes: 1 part white peony root, 1 part salvia miltiorrhiza, 1 part roselle, and 1 part tangerine peel.

[0014] Calculated by mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Rehmannia glutinosa, 1 part of Dioscorea batatas, 1 part of Polygonatum sibiricum, 1 part of Lycium barbarum, and 1 part of Prunus quinata.

[0015] The beneficial effects of the present invention are:

[0016] The smilax glabra series tea substitute of the present invention can be suitable for patients with different syndromes. All the component medicines in the tea substitute are medicines and foods of the same origin or traditional Chinese medicines that can be used in health food, and can be used for syndrome differentiation and adjustment of patients in the hyperuricemia stage and chronic gouty arthritis stage. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 This is a schematic diagram of the changes in blood uric acid in a clinical trial of a series of Smilax glabra tea substitutes applied in the present invention. DETAILED DESCRIPTION

[0018] The preferred embodiments of the present invention are further described below:

[0019] A series of wild smilax glabra tea substitutes, which include, by weight, 1 part of wild smilax glabra, 1 part of tuckahoe and 1 part of coix seed.

[0020] In terms of mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Prunus quinquefolia, 1 part of Alisma orientalis, 1 part of Phragmites australis, 1 part of Tangerine peel, and 1 part of Plantago seed.

[0021] In terms of mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Imperata cylindrica, 1 part of Lilium, 1 part of Dioscorea macrocephala, and 1 part of Adzuki bean.

[0022] Calculated by mass, the tea substitute also includes: 1 part white peony root, 1 part salvia miltiorrhiza, 1 part roselle, and 1 part tangerine peel.

[0023] Calculated by mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Rehmannia glutinosa, 1 part of Dioscorea batatas, 1 part of Polygonatum sibiricum, 1 part of Lycium barbarum, and 1 part of Prunus quinata.

[0024] The present application is further described below in conjunction with specific embodiments:

[0025] Example 1

[0026] The 1st recipe of Tu Fuling can move the spleen and remove dampness. By weight, this tea substitute includes: 1 part of Tu Fuling, 1 part of Fuling, 1 part of Atractylodes macrocephala, 1 part of Coix seed, 1 part of Wuzhimao peach, 1 part of Alisma orientalis, 1 part of Phragmites australis, 1 part of Tangerine peel, and 1 part of Plantago seed. It is aimed at patients with hyperuricemia and chronic gouty arthritis syndrome due to spleen deficiency and dampness obstruction. Such patients often like to eat fatty and sweet food, have heavy limbs, obesity, sticky stools, pale and fat tongue with tooth marks, and white and greasy tongue coating. Therefore, the prescription uses the Chinese yam-coix seed pair to invigorate the spleen and eliminate dampness, and to clear the joints. The Chinese yam-atractylodes macrocephala pair is modified from Sijunzi Decoction to invigorate the spleen to eliminate dampness. Tangerine peel is added to dry dampness and clear turbidity, Plantago seed and corn silk are diuretic and promote uric acid excretion, and reed root eliminates dampness without damaging yin, thereby improving the physical condition of patients with metabolic diseases. In addition, the Chinese yam-alismatis pair can promote diuresis, eliminate dampness and clear turbidity. The above nine ingredients work together to invigorate the spleen, eliminate dampness and clear turbidity.

[0027] Example 2

[0028] The recipe No. 2 of Wild Smilax glabra can clear away heat and remove dampness. Calculated by mass, this tea substitute includes: 1 part of Wild Smilax glabra, 1 part of Poria cocos, 1 part of Atractylodes macrocephala, 1 part of Coix seed, 1 part of Imperata root, 1 part of lily, 1 part of Dioscorea ternata, and 1 part of adzuki bean.

[0029] It is aimed at patients with hyperuricemia and chronic gouty arthritis with damp-heat accumulation. Such patients often have heavy limbs, restlessness, obesity, abdominal distension, lingering joint swelling and pain, palpable nodules, pale and fat tongue with tooth marks, and yellow and greasy tongue coating. Therefore, the prescription uses the Chinese smilax-Coix seed medicine pair to strengthen the spleen and eliminate dampness, and to clear the joints. The Chinese tuckahoe-Atractylodes macrocephala medicine pair is modified from the Four Gentlemen Decoction to move the spleen to eliminate dampness. The Radix Dioscoreae, corn silk, and red bean promote diuresis and promote uric acid excretion, and improve the physical condition of patients with metabolic diseases. The root of Imperatae is sweet and refreshing, clears heat and eliminates dampness. Lily nourishes yin and clears heat and contains a relatively rich amount of colchicine, which has an auxiliary therapeutic effect on gout attacks and joint pain. Gardenia is good at clearing the heat of the three burners, and the combination of the above medicines strengthens the effect of clearing heat and eliminating dampness.

[0030] Example 3

[0031] The recipe No. 3 of Wild Smilax glabra can eliminate phlegm and resolve blood stasis. Calculated by mass, this tea substitute includes: 1 part of Wild Smilax glabra, 1 part of Poria cocos, 1 part of Coix seed, 1 part of White Peony Root, 1 part of Salvia miltiorrhiza, 1 part of Roselle, and 1 part of Tangerine Peel.

[0032] For patients with hyperuricemia and chronic gouty arthritis with phlegm, blood stasis and numbness, this type of joint swelling and pain recurs repeatedly, local dark red nodules, tingling in joints, poor flexion and extension, dark purple tongue, and greasy white fur. Therefore, the prescription uses the Chinese smilax-coix seed medicine pair to invigorate the spleen and eliminate dampness, unblock the joints, white peony root and Poria invigorate the spleen, penetrate dampness and promote diuresis, tangerine peel removes dampness and resolves phlegm, turmeric promotes blood circulation and removes blood stasis, relieves numbness and relieves pain, and is effective for patients with joint pain, salvia removes blood stasis and promotes blood circulation, roselle regulates qi and relieves depression, and the above medicines are combined to enhance the effect of promoting blood circulation and removing blood stasis.

[0033] Example 4

[0034] The recipe No. 3 of Wild Smilax glabra can strengthen the spleen and kidney. Calculated by weight, this tea substitute includes: 1 part of Wild Smilax glabra, 1 part of Poria cocos, 1 part of Atractylodes macrocephala, 1 part of Coix seed, 1 part of Rehmannia glutinosa, 1 part of Dioscorea batatas, 1 part of Polygonatum sibiricum, 1 part of Lycium barbarum, and 1 part of Fructus quinquefolii.

[0035] For patients with hyperuricemia and chronic gouty arthritis, which are caused by spleen and kidney deficiency, in addition to joint pain and poor flexion and extension, these patients are often accompanied by fatigue, soreness of waist and knees, heaviness of limbs, pale tongue with thin white fur, etc. Therefore, the prescription uses the Chinese smilax-Coix seed drug pair to invigorate the spleen and eliminate dampness, and to clear the joints. The Chinese tuckahoe-Atractylodes macrocephala drug pair is modified from Sijunzi Decoction to invigorate qi and invigorate the spleen. Rehmannia and Chinese yam are taken from the formula of Dihuang Pills to invigorate the kidney and invigorate the spleen. Polygonatum sibiricum can both invigorate the spleen and nourish the kidney and replenish essence. Lycium barbarum, as a common medicine and food in life, is a good medicine for nourishing the liver and kidneys. Five-fingered peach invigorates qi and replenishes deficiency.

[0036] A total of 63 patients were enrolled in a hospital for preliminary efficacy evaluation, and the specific results are shown in Table 1. * Compared with the control group, the tea substitute group had a P value less than 0.05.

[0037] Table 1 Clinical effects of this application

[0038]

[0039] Note: *P<0.05, there is a statistical difference between the tea substitute group and the control group.

[0040] Mr. Li, male, 59 years old, diagnosed with gout for several years, did not use medication in a standardized manner, first affected the right toe, 2021-11UA634umol / L. 2022-1-21TG 2.25, LDL3.4. Sticky stool, tenesmus, dark tongue with greasy coating, slippery pulse. After 6 months of using the Tu Fuling series tea substitute of this application, the blood uric acid level dropped from about 600 to about 300. Specifically, Figure 1 shown.

[0041] The present application is a series of tea substitutes for Smilax glabra for patients with hyperuricemia and chronic gouty arthritis. The series of tea substitutes is mainly composed of Smilax glabra, which is also known as Yu Yuliang, cold rice balls, and Xian Yiliang. It is sweet and flat in nature. The Compendium of Materia Medica contains the effect of "strengthening the spleen and stomach, strengthening tendons and bones, removing rheumatism, benefiting joints, and treating cramps and bone pain". In addition, modern pharmacological studies have shown that the main chemical components of Smilax glabra include glycosides, flavonoids, organic acids, etc., among which flavonoids can effectively inhibit the components of xanthine oxidase, thereby reducing the generation of uric acid, and the components such as epicatechin, quercetin, and new astilbin can effectively prevent and treat hyperuricemia and gout by inhibiting xanthine oxidase to promote uric acid excretion.

[0042] The inventor of this application proposed that gout is based on "spleen deficiency and dampness" as the basic pathogenesis by summarizing the results of previous clinical and scientific research, and achieved good results in treating hyperuricemia and gouty arthritis by the method of moving the spleen and eliminating dampness. Combined with the "Guidelines for the Diagnosis and Treatment of Gout and Hyperuricemia" and other guideline standards and relevant clinical studies of the Rheumatology Branch of the Chinese Association of Traditional Chinese Medicine, this application summarizes the four main syndromes of hyperuricemia and chronic gouty arthritis, namely spleen deficiency and dampness obstruction syndrome, damp-heat accumulation syndrome, phlegm and blood stasis syndrome, and spleen and kidney deficiency syndrome. And successively formulated Tu Fuling tea drinks suitable for patients with different syndromes, all the component drugs in the tea drinks are medicines and food homologous drugs or Chinese medicines that can be used for health foods.

[0043] Although the technical solutions of the present invention have been described and listed in detail, it should be understood that it is obvious to those skilled in the art to make modifications to the above embodiments or adopt equivalent alternatives. These modifications or improvements made without departing from the spirit of the present invention are within the scope of protection required by the present invention.

Claims

1. A tea substitute of a series of smilax glabra, characterized in that: Calculated by mass, the tea substitute includes: 1 part of wild yam, 1 part of tuckahoe, and 1 part of coix seed.

2. A tea substitute for Smilax glabra series according to claim 1, characterized in that: In terms of mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Prunus quinquefolia, 1 part of Alisma orientalis, 1 part of Phragmites australis, 1 part of Tangerine peel, and 1 part of Plantago seed.

3. A tea substitute for Smilax glabra series according to claim 1, characterized in that: Calculated by mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Imperata cylindrica, 1 part of Lilium, 1 part of Dioscorea macrocephala, and 1 part of Adzuki bean.

4. A series of tea substitutes of Smilax glabra according to claim 1, characterized in that: Calculated by mass, the tea substitute also includes: 1 part white peony root, 1 part salvia miltiorrhiza, 1 part roselle, and 1 part tangerine peel.

5. A series of tea substitutes of Smilax glabra according to claim 1, characterized in that: Calculated by mass, the tea substitute also includes: 1 part of Atractylodes macrocephala, 1 part of Rehmannia glutinosa, 1 part of Dioscorea batatas, 1 part of Polygonatum sibiricum, 1 part of Lycium barbarum, and 1 part of Prunus quinata.