A novel device and method for the preparation of hollow microneedles

Abstract

The present application relates to the technical field of hollow microneedle preparation, and more particularly to a novel preparation device and method of hollow microneedle. The hollow microneedle manufacturing platform is obtained through the combination of punch, guide plate and die piercing, and the platform can cast through-hole microneedle in one step. Compared with the shell structure microneedle manufactured by the traditional micro-forming method, the through-hole microneedle has better mechanical properties and is easier to pierce the stratum corneum. Meanwhile, the manufacturing platform can be repeatedly used for multiple times to produce hollow microneedles, meeting the low-cost technical requirements. By adding different biocompatible polymer solutions, the platform can be used to produce hollow microneedles made of different materials. By changing the concave shape of the die, the platform can be used to produce hollow microneedle patches with different shapes.

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