Application of oil control composition containing oil-soluble functional components in daily chemicals

Abstract

The invention provides an application of an oil control composition containing oil-soluble functional components in daily chemicals. The oil control composition comprises the following components in percentage by mass: 10-50% of oil soluble functional components, 30-85% of a solvent and 5-20% of a solubilizer. The oil-control composition containing oil-soluble functional components designed by the invention has better application effects in both resident products and wash-off products than those of traditional oil-control components such as PCA zinc, nicotinamide, capryloyl glycine and the like; the oil-control composition containing the oil-soluble functional components, designed by the invention, can be added at normal temperature in formula application, and is convenient to apply.

Description

Technical Field

[0001] The invention relates to an application of an oil control composition, belonging to the technical field of daily chemicals, and in particular to an application of an oil control composition having an oil-soluble oil control / anti-dandruff functional compound in daily chemicals. Background Art

[0002] With the rapid economic development, air pollution, climate change, faster pace of life, greater work pressure and many other factors have an impact on people's scalp health. Oily scalp, dandruff, hair loss and itchy scalp are all common scalp problems. These scalp problems are interrelated and related to sebum secretion, barrier damage, scalp inflammatory response and scalp microecology.

[0003] Abnormal sebum secretion, on the one hand, will cause the unsaturated fatty acids and squalene in the sebum to be oxidized, irritate the scalp, and cause an inflammatory reaction in the scalp; on the other hand, excessive oil secretion can be easily utilized by scalp microorganisms such as Malassezia, leading to an imbalance in the scalp microecology, damage to the scalp barrier, and the production of dandruff.

[0004] At present, most oil-control ingredients, such as PCA zinc and niacinamide, are highly water-soluble and can be used in leave-on products to control oil. However, due to their strong polarity and difficulty in penetrating the skin, the effectiveness of water-soluble oil-control ingredients in leave-on products is limited.

[0005] These water-soluble oil-control ingredients are used in rinse-off products such as shampoo. Since rinse-off products require a large amount of water to cleanse, it is difficult for them to remain on the skin and exert their effects. Summary of the invention

[0006] In order to overcome the deficiencies of the prior art, the object of the present invention is to provide an oil control composition containing oil-soluble functional ingredients and its application in daily chemicals. The oil control composition containing oil-soluble oil control ingredients of the present invention can be added at room temperature in the formulation application and is easy to use.

[0007] The invention provides an oil-control composition containing oil-soluble functional ingredients and application of the composition in daily chemicals.

[0008] Calculated by mass percentage, the oil control composition comprises: 10-50% oil-soluble functional ingredients, 30-85% solvent, and 5-20% solubilizer.

[0009] The oil-soluble effective ingredients are selected from one or more of quercetin, hesperetin, nobiletin, baicalin, naringenin, betulin, resveratrol, clarylide, koreanolide, andrographolide, honokiol and magnolol.

[0010] Preferably, the oil-soluble effective ingredient is selected from quercetin, clarylide, sclareolide, and magnolol; magnolol.

[0011] The solvent is selected from polyols, including but not limited to one or more of glycerol, propylene glycol, butylene glycol, pentanediol, hexylene glycol, diglycerol, and the like.

[0012] Preferably, the solvent is selected from one or more of propylene glycol, butylene glycol and hexylene glycol.

[0013] The solubilizing agent is selected from one or more of nonionic surfactants, anionic surfactants, amphoteric surfactants and cationic surfactants.

[0014] Preferably, the oil control composition comprises, by mass percentage: 10-50% of oil-soluble functional ingredients, 40-85% of solvents, and 5-15% of solubilizers.

[0015] Preferably, the oil control composition comprises, by mass percentage: 10-40% of oil-soluble functional ingredients, 40-70% of solvents, and 5-15% of solubilizers.

[0016] Preferably, the oil control composition comprises, by mass percentage: 20-40% oil-soluble functional ingredients, 50-70% solvent, and 10-15% solubilizer.

[0017] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0018] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%;

[0019] Propylene glycol and / or butylene glycol 20-70%;

[0020] Laureth-21 and / or Lauryl Glucoside 5-15%.

[0021] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0022] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%;

[0023] Propylene glycol and / or butylene glycol 50-70%;

[0024] Laureth-21 and / or Lauryl Glucoside 10-15%.

[0025] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0026] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; propylene glycol 50-70%; laureth-21 5-15%.

[0027] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0028] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; butylene glycol 50-70%; laureth-21 5-15%.

[0029] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0030] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; propylene glycol 15-25%, butylene glycol 25-35%; laureth-21 5-15%.

[0031] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0032] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; propylene glycol 50-70%; lauryl glucoside 5-10%.

[0033] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0034] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; butanediol 50-70%; lauryl glucoside 5-10%.

[0035] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0036] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; propylene glycol 15-25%, butylene glycol 25-35%; lauryl glucoside 5-10%.

[0037] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0038] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; propylene glycol 50-70%; laureth-21 10-15%, lauryl glucoside 5%.

[0039] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0040] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; butylene glycol 50-70%; laureth-21 10-15%, lauryl glucoside 5%.

[0041] Preferably, the oil control composition is composed of the following ingredients by mass percentage:

[0042] Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; propylene glycol 15-25%, butylene glycol 25-35%; laureth-21 10-15%, lauryl glucoside 5%.

[0043] The preparation method of the oil control composition is: directly mixing and stirring the oil-soluble functional component, the solvent and the solubilizer at room temperature until the oil-soluble functional component is completely dissolved.

[0044] The oil-control composition containing oil-soluble functional ingredients can be applied to various daily chemicals, including but not limited to: facial oil-control essence, oil-control cream, oil-control shampoo, oil-control scalp essence and other products.

[0045] The oil-control composition containing the oil-soluble functional ingredients can be used in a formula by directly adding it into the prepared daily chemicals at room temperature.

[0046] Preferably, the daily chemical product is a facial oil-control essence, and the facial oil-control essence comprises the following formula by mass percentage:

[0047] Sclerotium gum 0.5%, p-hydroxyacetophenone 0.3%, phenoxyethanol 0.25%, essence 0.02%, PEG-40 hydrogenated castor oil 0.1%, oil control composition 0.3-1%, water balance;

[0048] The preparation method of the facial oil-control essence comprises the following steps:

[0049] S1. Add water and sclerotium gum into the emulsifier, homogenize until completely dispersed, start stirring, heat to 75-85℃, and keep warm for 20-30min;

[0050] S2. Add p-hydroxyacetophenone and phenoxyethanol into the emulsifying pot and stir at 75°C for 5-10 minutes;

[0051] S3, cooling the material prepared in step S2 to below 40° C., adding the premixed essence and PEG-40 hydrogenated castor oil, and stirring and dispersing for 5-10 minutes;

[0052] S4. Add the oil control composition to the material prepared in step S3, and stir for 5-20 minutes until the material is evenly dispersed to obtain the facial oil control essence.

[0053] Preferably, the daily chemical is an oil-control shampoo, and the oil-control shampoo comprises the following formula by mass percentage:

[0054] Cationic guar gum 0.3%, lauryl hydroxysultaine 30%, sodium cocoyl isethionate 5%, citric acid 0.08%, phenoxyethanol 0.5%, sodium benzoate 0.4%, essence 0.6%, oil control composition 1-3%, balance water;

[0055] The preparation method of the oil-control shampoo comprises the following steps:

[0056] S1. Add water and cationic guar gum into an emulsifying pot, homogenize until completely dispersed, start stirring, heat to 75-85°C, and keep warm for 10-30 minutes;

[0057] S2. Add lauryl hydroxysultaine and sodium cocoyl isethionate into the emulsifier in sequence, and stir at 75°C for 20-30 minutes;

[0058] S3, cooling the material prepared in step S2 to below 40°C, adding citric acid, phenoxyethanol, sodium benzoate, and essence in sequence, and stirring and dispersing for 10-20 minutes;

[0059] S4. Add the oil-control composition to the material prepared in step S3, and stir for 5-20 minutes until the material is evenly dispersed to obtain the oil-control shampoo.

[0060] By means of the above technical solution, the beneficial effects of the present invention are:

[0061] 1) The oil-control composition containing the oil-soluble oil-control ingredient designed by the present invention has better efficacy than traditional oil-control ingredients such as PCA zinc, niacinamide, and capryloyl glycine, whether used in a leave-on product or a rinse-off product;

[0062] 2) The oil control composition containing the oil-soluble oil control component designed by the present invention can be added at room temperature during formulation application, and is easy to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0063] Figure 1 This is the relative fluorescence intensity analysis of neutral lipids at different concentrations of the active ingredient quercetin in Example 1;

[0064] Figure 2 This is an example of the relative fluorescence intensity of neutral lipids at different concentrations of the active ingredient quercetin in Example 1;

[0065] Figure 3 This is the relative fluorescence intensity analysis of neutral lipids at different concentrations of the active ingredient sclareolide in Example 2;

[0066] Figure 4This is an example of the relative fluorescence intensity of neutral lipids at different concentrations of the active ingredient sclareolide in Example 2;

[0067] Figure 5 This is the relative fluorescence intensity analysis of neutral lipids at different concentrations of the active ingredient rosin lactone in Example 3;

[0068] Figure 6 This is an example of the relative fluorescence intensity of neutral lipids at different concentrations of the active ingredient rosin lactone in Example 3;

[0069] Figure 7 This is the relative fluorescence intensity analysis of neutral lipids at different concentrations of the active ingredient magnolol in Example 4;

[0070] Figure 8 This is an example of the relative fluorescence intensity of neutral lipids at different concentrations of the active ingredient and magnolol in Example 4;

[0071] Fig. 9 This is the relative fluorescence intensity analysis of neutral lipids at different concentrations of magnolol, the active ingredient in Example 5;

[0072] Fig.10 This is an example of the relative fluorescence intensity of neutral lipids at different concentrations of the active ingredient magnolol in Example 5. DETAILED DESCRIPTION

[0073] In order to better illustrate the content of the present invention, the present invention is described in detail below in conjunction with embodiments. However, these specific embodiments are only for better illustrating the content of the present invention, rather than limiting the content of the present invention.

[0074] The present invention provides an application of an oil-control composition containing oil-soluble functional ingredients in daily chemicals, wherein the oil-soluble functional ingredients are selected from one or more of quercetin, hesperetin, nobiletin, baicalein, naringenin, betulin, resveratrol, clarineolide, pinolactone, andrographolide, honokiol and magnolol.

[0075] The sebum inhibition rate results on human sebaceous gland cells at a concentration of 0.15 μg / mL were: 56.39% for quercetin, 53.18% for sclareolide, 64.46% for clarylidene lactone, 56.17% for magnolol, and 64.39% for magnolol.

[0076] The present invention provides an oil control composition containing oil-soluble functional ingredients and its application in daily chemicals. The oil control composition comprises, by mass percentage, 10-50% of oil-soluble functional ingredients, 30-85% of solvents, and 5-20% of solubilizers.

[0077] The present invention provides an oil control composition containing oil-soluble functional ingredients and its application in daily chemicals. The oil control composition comprises, by mass percentage, 10-50% of oil-soluble functional ingredients, 40-85% of solvents, and 5-15% of solubilizers.

[0078] The present invention provides an oil control composition containing oil-soluble functional ingredients and its application in daily chemicals. The oil control composition comprises, by mass percentage, 20-40% of oil-soluble functional ingredients, 40-70% of solvents, and 5-15% of solubilizers.

[0079] The oil-soluble effective ingredients are selected from one or more of quercetin, hesperetin, nobiletin, baicalein, naringenin, betulin, resveratrol, clarylide, pinolactone, andrographolide, honokiol and magnolol.

[0080] Preferably, the oil-soluble effective ingredient is selected from quercetin, clarylide, sclareolide, and magnolol; magnolol.

[0081] The solvent is selected from polyols, including but not limited to one or more of glycerol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, diglycerol, and the like.

[0082] Preferably, the solvent is selected from one or more of propylene glycol, butylene glycol and hexylene glycol.

[0083] The solubilizing agent is selected from one or more of nonionic surfactants, anionic surfactants, amphoteric surfactants, and cationic surfactants.

[0084] The nonionic surfactant is selected from but not limited to: decyl glucoside, C12-16 alkyl glucoside, lauryl glucoside, C12-14 paraeth-12, ceteth-21, laureth-21, isoceteth-20, cocamide, cocamide methyl MEA, cocamide DEA, cocamide MEA, cocamide MIPA, lauramide DEA, lauramide MEA, lauramide MIPA, myristicamide DEA, myristicamide MEA, PEG-20 cocamide MEA, PEG-2 cocamide, PEG-3 cocamide, PEG-4 cocamide, PEG-5 cocamide, PEG-6 cocamide, PEG-7 cocamide, PEG-3 lauramide, PEG-5 lauramide, PEG-3 oleamide, PPG-2 cocamide, PPG-2 hydroxyethyl cocamide, etc. One or more.

[0085] The anion is selected from but not limited to dialkyl ammonium sulfate, ammonium lauryl polyoxyethylene ether sulfate, triethylamine lauryl sulfate, triethylamine lauryl polyoxyethylene ether sulfate, triethanolamine lauryl sulfate, triethanolamine lauryl polyoxyethylene ether sulfate, monoethanolamine lauryl sulfate, monoethanolamine lauryl polyoxyethylene ether sulfate, diethanolamine lauryl sulfate, diethanolamine lauryl polyoxyethylene ether sulfate, sodium lauric acid monoglyceride sulfate, sodium lauryl sulfate, sodium lauryl polyoxyethylene ether sulfate, potassium lauryl sulfate, potassium lauryl polyoxyethylene ether sulfate, ammonium coconut sulfate, ammonium dodecanoyl sulfate, sodium coconut sulfate, sodium lauroyl sulfate, potassium coconut sulfate, lauryl Potassium sulfate, triethanolamine lauryl sulfate, triethanolamine lauryl sulfate, monoethanolamine cocoyl sulfate, monoethanolamine lauryl sulfate, sodium cocoyl glutamate, disodium cocoyl glutamate, ammonium cocoyl glutamate, diammonium cocoyl glutamate, sodium lauroyl glutamate, disodium lauroyl glutamate, sodium cocoyl hydrolyzed wheat protein glutamate, disodium cocoyl hydrolyzed wheat protein glutamate, potassium cocoyl glutamate, dipotassium cocoyl glutamate, potassium lauroyl glutamate, dipotassium lauroyl glutamate, potassium cocoyl hydrolyzed wheat protein glutamate, dipotassium cocoyl hydrolyzed wheat protein glutamate, sodium capryloyl glutamate, disodium capryloyl glutamate, Potassium octanoyl glutamate, dipotassium octanoyl glutamate, sodium undecylenyl glutamate, disodium undecylenyl glutamate, potassium undecylenyl glutamate, dipotassium undecylenyl glutamate, disodium hydrogenated tallow glutamate, sodium stearoyl glutamate, disodium stearoyl glutamate, potassium stearoyl glutamate, dipotassium stearoyl glutamate, sodium myristoyl glutamate, disodium myristoyl glutamate, potassium myristoyl glutamate, dipotassium myristoyl glutamate, sodium cocoyl / hydrogenated tallow glutamate, sodium cocoyl / palmitoyl / sunflower acyl glutamate, sodium hydrogenated tallow acyl glutamate, sodium oliveoyl glutamate, disodium oliveoyl glutamate, palm One or more of sodium palmitoyl glutamate, disodium palmitoyl glutamate, sodium cocoyl alanine, sodium lauroyl alanine, sodium lauroyl sarcosinate, sodium cocoyl sarcosinate, sodium myristoyl sarcosinate, sodium cocoyl glycinate, sodium lauroyl glycinate, sodium lauroyl methyl isethionate, sodium cocoyl isethionate, ammonium cocoyl isethionate, hydrogenated sodium cocoyl methyl isethionate, sodium lauroyl isethionate, sodium cocoyl methyl isethionate, sodium myristoyl isethionate, sodium oleoyl isethionate, sodium oleyl methyl isethionate, sodium palm kernel isethionate, sodium stearoyl methyl isethionate.

[0086] The amphoteric surfactant is selected from but not limited to cocodimethyl carboxymethyl betaine, cocoamidopropyl betaine (CAPB), cocodimethyl betaine, laurylamidopropyl betaine (LAPB), oleyl betaine, lauryl dimethyl carboxymethyl betaine, lauryl dimethyl α-carboxyethyl betaine, cetyl dimethyl carboxymethyl betaine, lauryl di-(2-hydroxyethyl) carboxymethyl betaine, stearyl di-(2-hydroxypropyl) carboxymethyl betaine, oleyl dimethyl γ-carboxypropyl betaine, lauryl di-(2-hydroxypropyl) α-carboxyethyl betaine, cocodimethyl sulfopropyl betaine, stearyl dimethyl sulfopropyl betaine, lauryl dimethyl sulfoethyl betaine, lauryl di-(2-hydroxyethyl) sulfopropyl betaine, and one or more of the like.

[0087] The cationic surfactant is selected from but not limited to alkylamine salts, fatty acid amide amine salts, and alkyl quaternary ammonium salts. Specifically, the cationic surfactant is selected from but not limited to one or more of stearamidopropyl dimethylamine, stearamidopropyl dimethylamine lactate, cocamidopropyl dimethylamine, behenamidopropyl dimethylamine, palmitamidopropyl trimethyl ammonium chloride, etc.

[0088] Test example of oil-control effect of oil-soluble functional ingredients

[0089] The oil-control efficacy test of the oil-soluble functional ingredients of the present invention is conducted on human sebaceous gland cells.

[0090] Method for testing oil control efficacy using human sebaceous gland cells:

[0091] 1. Cell activity detection:

[0092] 1) Cell inoculation: Inoculate the cell suspension into a 96-well cell culture plate and culture overnight.

[0093] 2) Experimental grouping: The experiment was divided into a zero adjustment group, a blank control group (BC) and a sample group. In the sample group, each sample was set with 8 concentration gradients, and 6 replicate wells were set under each concentration gradient.

[0094] 3) Administration: 100 μL of cell culture medium was added to each well of the control group; 100 μL of culture medium containing samples of corresponding concentrations was added to each well of the sample group; no cells were inoculated in the zero adjustment group, and only 100 μL of cell culture medium was added. After the addition of the test substance, the 96-well plate was placed in a carbon dioxide incubator and cultured for 48 hours.

[0095] 4) Cell activity detection: discard the supernatant, add medium containing MTT to each well, and incubate in a carbon dioxide incubator in the dark for 3 hours. After the incubation, discard the supernatant, add 100 μL DMSO to each well, and measure the absorbance at a wavelength of 570 nm on an enzyme reader.

[0096] 2. Calculation of cell viability:

[0097] Calculate cell viability according to the cell viability formula:

[0098] Cell viability (%) = (OD of sample group - OD of zero-adjusted group) / (OD of blank control group - OD of zero-adjusted group)*100%.

[0099] 3. Lipid staining:

[0100] (1) Cell inoculation: Cells were inoculated into culture dishes and cultured overnight.

[0101] (2) Experimental grouping: The experiment set up a blank control group (BC), a model group (M), a positive control group (PC) and a sample group (TA). The sample group was set up with 3 concentration gradients, and 3 replicates were set up under each concentration gradient.

[0102] (3) Induction and administration: The blank control group was added with only 2 mL of cell culture medium, the model group was added with 2 mL of cell culture medium containing linoleic acid, the positive control group was added with 2 mL of cell culture medium containing linoleic acid and retinoic acid, and the sample group was added with 2 mL of cell culture medium containing linoleic acid and the test concentration sample. The cells were incubated in a carbon dioxide incubator for 48 h.

[0103] (4) Staining: After incubation, discard the supernatant, add 1 mL of PBS to wash the cell layer, add 500 μL of paraformaldehyde and fix at room temperature for 5 min, wash twice with 1 mL of PBS, add 500 μL of Nile red dye, and incubate at 37°C in the dark for 15 min.

[0104] (5) Observation under a fluorescence microscope: Wash twice with 1 mL of PBS and then observe under an inverted phase-contrast fluorescence microscope.

[0105] 4. Calculation of lipid fluorescence intensity:

[0106] Image analysis was performed, and the relative fluorescence intensity of each group was calculated with the model group (M) as 100%.

[0107] Table 1: Cell viability of selected oil-controlling ingredients

[0108]

[0109] Table 2: Relative fluorescence intensity and sebum secretion inhibition rate of neutral lipids of preferred oil-controlling efficacy ingredients

[0110]

[0111]

[0112] The experimental data were normalized with the content of the model group. Statistical analysis was performed using the t-test method. Compared with the M group, significance was indicated by *, P-value < 0.05 was indicated by *, P-value < 0.01 was indicated by **, P-value < 0.001 was indicated by ***, and ns indicated no significant difference.

[0113] From Table 2 and Figure 1-Figure 10 It can be seen that the oil-soluble functional ingredients used in the present invention have excellent sebum secretion inhibition rates. At a concentration of 0.15 μg / mL, the sebum inhibition rates of quercetin, sclarea lactone, sclarea lactone, sclarea lactone, honokiol, and magnolol were 56.17% and 64.39%, respectively.

[0114] Oil-soluble ingredients have low solubility in water and are difficult to be used in daily chemical formulations. The oil-control composition containing oil-soluble functional ingredients of the present invention can improve the application performance and effect of the oil-soluble ingredients in the formulation.

[0115] Oil Control Composition Examples 1-5 and Comparative Examples 1-5

[0116] Table 3 shows the composition of the oil control composition of the present invention (mass percentage %)

[0117]

[0118]

[0119] The preparation method of the oil control composition is: directly mixing, stirring and dispersing the oil-soluble functional component, the solvent and the solubilizer at room temperature until the oil-soluble functional component is completely dissolved.

[0120] Table 4 shows the comparative composition of the oil control composition (mass percentage %)

[0121] Components Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 PCA Zinc 20 -- -- -- 10 Niacinamide -- 30 -- 30 -- Capryloyl Glycine -- -- 20 -- 20 Propylene glycol 70 60 -- 10 -- Butanediol -- -- 70 50 60 Laureth-21 10 -- 10 10 -- Lauryl Glucoside -- 10 -- -- 10

[0122] The preparation method of the oil control composition of the comparative example is: mixing and stirring the components uniformly at room temperature.

[0123] Application Examples 1-5 and Comparative Examples 1-5 of the Oil Control Composition in the Oil Control Essence

[0124] Application of the oil control composition of the present invention in oil control essence.

[0125] Table 5 is the formula composition of the oil control essence application example (mass percentage %)

[0126]

[0127] Table 6 is the formula composition of the comparative example of oil control essence application (mass percentage %)

[0128]

[0129] The preparation method of the oil-control essence of application examples 1-5 and application comparative examples 1-5 of the present invention comprises the following steps:

[0130] S1. Add the water and sclerotium gum of phase A into the emulsifier, homogenize until completely dispersed, start stirring, heat to 75°C, and keep warm for 30 minutes;

[0131] S2, add p-hydroxyacetophenone and phenoxyethanol in phase B into the emulsifying pot, keep stirring at 75°C for 10 minutes;

[0132] S3, cooling the material prepared in step S2 to below 40°C, adding the premixed phase C, i.e., the premix of the essence and PEG-40 hydrogenated castor oil, and stirring and dispersing for 10 minutes;

[0133] S4. Add phase D to the material prepared in step S3, and stir for 20 minutes until the material is evenly dispersed to obtain the oil-control essence.

[0134] 1. Oil control effect test:

[0135] Test subjects: People aged 20 to 40 with oily skin. 50 subjects were randomly divided into five groups, with 10 people in each group.

[0136] Test method: The test site is the forehead. Before the test, the subjects need to clean their faces uniformly and wipe them clean with a dry, absorbent paper towel. The subjects use it once a day for 14 consecutive days, and the amount used each time is 0.2 ml.

[0137] Product usage grouping: Application Examples 1-5 and Application Comparative Examples 1-5 were blindly tested and numbered as HPR, ZSR, HSR, HFR, BFR, HPL, ZSL, HSL, HFL, and BFL. The first group of subjects used HPR on the right forehead (Application Example 1) and HPL on the left forehead (Application Comparative Example 1); the second group of subjects used ZSR on the right forehead (Application Example 2) and ZSL on the left forehead (Application Comparative Example 2); the third group of subjects used HSR on the right forehead (Application Example 3) and HSL on the left forehead (Application Comparative Example 3); the fourth group of subjects used HFR on the right forehead (Application Example 4) and HFL on the left forehead (Application Comparative Example 4); the fifth group of subjects used BFR on the right forehead (Application Example 5) and BFL on the left forehead (Application Comparative Example 5).

[0138] 2. Evaluation of oil control effect:

[0139] On day 0, the subjects cleaned their faces uniformly without using any products. Eight hours after cleansing, the sebum content of the forehead was tested using CK as the initial value of the sebum content before use.

[0140] At 8 hours after using the product on the 7th and 14th days, the sebum content of the forehead was tested using CK as the sebum content test values ​​on the 7th and 14th days.

[0141] Change rate of forehead sebum secretion amount (%) = (forehead sebum secretion amount after use - sebum secretion amount before use) / forehead sebum secretion amount before use × 100%.

[0142] Table 7 Evaluation results of the oil control efficacy of the oil control essence application examples and comparative examples.

[0143]

[0144] It can be seen from Table 7 that the oil control composition of the present invention has a better oil control effect in a leave-on product than the traditional water-soluble oil control component.

[0145] Application Examples 6-10 and Comparative Examples 6-10 of the Oil Control Composition in Oil Control Shampoo

[0146] Table 8 Application Example Formula Composition in Oil Control Shampoo (Mass Percentage %)

[0147]

[0148]

[0149] Table 9 Application Comparative Example Formula Composition in Oil Control Shampoo (Mass Percentage %)

[0150]

[0151] The preparation method of the oil-control shampoo of application examples 6-10 and application comparative examples 6-10 of the present invention comprises the following steps:

[0152] S1. Add the water and cationic guar gum of phase A into the emulsifier, homogenize until completely dispersed, start stirring, heat to 75°C, and keep warm for 30 minutes;

[0153] S2. Add lauryl hydroxysultaine and sodium cocoyl isethionate of phase B into the emulsifier in sequence, and stir at 75°C for 30 minutes;

[0154] S3, cool the material prepared in step S2 to below 40°C, add the raw materials of phase C in sequence, and stir and disperse for 20 minutes;

[0155] S4. Add phase D to the material prepared in step S3, and stir for 20 minutes until the material is evenly dispersed to obtain an oil-control shampoo.

[0156] 3. Oil control effect test:

[0157] Test subjects: 20 to 40 years old, people with oily scalp, 50 subjects were randomly divided into five groups, 10 people in each group, and no other hair products could be used during the test. Each subject voluntarily participated in the test and signed an informed consent form.

[0158] Test method: The embodiment and the comparative example were tested on half of the head, that is, the right side used the embodiment and the left side used the comparative example. Before the test, the subjects were required to uniformly use the blank shampoo of the composition without the oil control effect for a 1-week wash period. The subjects used it once every 2 days for 8 consecutive times, and the amount used for half of the head each time was 10 ml. The same shampooing expert washed half of the subject's head during the shampooing process.

[0159] Product usage grouping: Application Examples 6-10 and Application Comparative Examples 6-10 were blindly tested and numbered as HPR, ZSR, HSR, HFR, BFR, HPL, ZSL, HSL, HFL, and BFL. The first group of subjects used HPR (Application Example 6) on the right side of the head, and HPL (Application Comparative Example 6) on the left side of the head; the second group of subjects used ZSR (Application Example 7) on the right side of the head, and ZSL (Application Comparative Example 7) on the left side of the head; the third group of subjects used HSR (Application Example 8) on the right side of the head, and HSL (Application Comparative Example 8) on the left side of the head; the fourth group of subjects used HFR (Application Example 9) on the right side of the head, and HFL (Application Comparative Example 9) on the left side of the head; the fifth group of subjects used BFR (Application Example 10) on the right side of the head, and BFL (Application Comparative Example 10) on the left side of the head.

[0160] Oil control effect evaluation:

[0161] Determination of initial sebum secretion: After the last wash of the 1-week wash with blank shampoo, the subjects shaved a specific area of ​​1.5cm*1.5cm on both sides of the top of the head symmetrically. Before the test wash two days later, CK was used to test the initial value of the sebum content on the top of the head.

[0162] Measurement of sebum secretion after using the product: Track the results once a week. Shave the selected specific area before washing your hair (i.e. the 3rd and 7th washings) and use CK to test the sebum secretion of the scalp the day after the 4th and 8th washings.

[0163] Change rate of scalp sebum secretion amount (%) = (scalp sebum secretion amount after use - scalp sebum secretion amount before use) / scalp sebum secretion amount before use × 100%.

[0164] Table 9 Evaluation results of oil control efficacy of oil control shampoo application examples and comparative examples

[0165]

[0166] It can be seen from Table 9 that the oil control effect of the oil-soluble functional ingredient-containing oil control composition of the present invention when used in shampoo is much better than the oil control effect of the traditional water-soluble ingredient when used in shampoo.

[0167] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Therefore, any simple modification, equivalent change and modification made to the above embodiment according to the technical essence of the present invention without departing from the technical solution of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. Application of an oil-control composition containing an oil-soluble functional ingredient in daily chemicals, characterized in that: The oil control composition is composed of the following components by mass percentage: 10-50% oil-soluble active ingredients, 30-85% solvent, 5-20% solubilizer; The oil-soluble effective ingredients are selected from one or more of quercetin, hesperetin, nobiletin, baicalein, naringenin, betulin, resveratrol, clarylide, pinolactone, andrographolide, honokiol and magnolol.

2. Use of the oil-control composition containing the oil-soluble functional ingredient according to claim 1 in daily chemicals, characterized in that: The oil-soluble effective ingredient is selected from any one of quercetin, clarylide, sclareolide and magnolol.

3. Use of the oil-control composition containing the oil-soluble functional ingredient according to claim 1 in daily chemicals, characterized in that: The solvent is selected from polyols, including but not limited to one or more of glycerol, propylene glycol, butylene glycol, pentanediol, hexylene glycol, and diglycerol; The solvent is selected from one or more of propylene glycol, butylene glycol, and hexylene glycol; The solubilizing agent is selected from one or more of nonionic surfactants, anionic surfactants, amphoteric surfactants, and cationic surfactants.

4. Use of the oil control composition containing the oil-soluble functional ingredient according to any one of claims 1 to 3 in daily chemicals, characterized in that: The oil control composition is composed of the following components by mass percentage: 10-40% of oil-soluble functional ingredients, 40-85% of solvents, and 5-15% of solubilizers.

5. Use of the oil-control composition containing the oil-soluble functional ingredient as claimed in claim 4 in daily chemicals, characterized in that: The oil control composition is composed of the following components by mass percentage: 20-40% oil-soluble active ingredients, 40-70% solvent, 5-15% solubilizer.

6. Use of the oil-control composition containing the oil-soluble functional ingredient as claimed in claim 2 in daily chemicals, characterized in that: The oil control composition is composed of the following ingredients by mass percentage: Quercetin or clarylide or sclareolide or honokiol or magnolol 20-40%; Propylene glycol and / or butylene glycol 20-70%; Laureth-21 and / or Lauryl Glucoside 5-15%.

7. Use of the oil-control composition containing the oil-soluble functional ingredient as claimed in claim 6 in daily chemicals, characterized in that: The preparation method of the oil control composition is: At room temperature, the oil-soluble functional ingredients, solvent, and solubilizer are directly mixed, stirred, and dispersed until the oil-soluble functional ingredients are completely dissolved.

8. Use of the oil-control composition containing the oil-soluble functional ingredient according to any one of claims 1 to 7 in daily chemicals, characterized in that: The daily chemicals include but are not limited to: facial oil-control essence, oil-control cream, oil-control shampoo, oil-control scalp essence and other products.

9. Use of the oil-control composition containing the oil-soluble functional ingredient as claimed in claim 8 in daily chemicals, characterized in that: The daily chemical product is a facial oil control essence, which is composed of the following formula ingredients by mass percentage: Sclerotium gum 0.5%, p-hydroxyacetophenone 0.3%, phenoxyethanol 0.25%, essence 0.02%, PEG-40 hydrogenated castor oil 0.1%, oil control composition 0.3-1%, balance water; The preparation method of the facial oil-control essence comprises the following steps: S1. Add water and sclerotium gum into the emulsifier, homogenize until completely dispersed, start stirring, heat to 75-85℃, and keep warm for 20-30min; S2. Add p-hydroxyacetophenone and phenoxyethanol into the emulsifying pot and stir at 75°C for 5-10 minutes; S3, cooling the material prepared in step S2 to below 40° C., adding the premixed essence and PEG-40 hydrogenated castor oil, and stirring and dispersing for 5-10 minutes; S4. Add the oil control composition to the material prepared in step S3, and stir for 5-20 minutes until the material is evenly dispersed to obtain the facial oil control essence.

10. Use of the oil-control composition containing oil-soluble functional ingredients as claimed in claim 8 in daily chemicals, characterized in that: The daily chemical product is an oil-control shampoo, which comprises the following formula by mass percentage: Cationic guar gum 0.3%, lauryl hydroxysultaine 30%, sodium cocoyl isethionate 5%, citric acid 0.08%, phenoxyethanol 0.5%, sodium benzoate 0.4%, essence 0.6%, oil control composition 1-3%, balance water; The preparation method of the oil-control shampoo comprises the following steps: S1. Add water and cationic guar gum into an emulsifying pot, homogenize until completely dispersed, start stirring, heat to 75-85°C, and keep warm for 10-30 minutes; S2. Add lauryl hydroxysultaine and sodium cocoyl isethionate into the emulsifier in sequence, and stir at 75°C for 20-30 minutes; S3, cooling the material prepared in step S2 to below 40°C, adding citric acid, phenoxyethanol, sodium benzoate, and essence in sequence, and stirring and dispersing for 10-20 minutes; S4. Add the oil-control composition to the material prepared in step S3, and stir for 5-20 minutes until the material is evenly dispersed to obtain the oil-control shampoo.

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