Ultrasonic probe fixing device for mouse experiment

Abstract

The invention relates to the technical field of ultrasonic probe fixing, and discloses a mouse experiment ultrasonic probe fixing device which comprises a stand column installed between an operating bedplate and a probe body, the lower end of the stand column is fixedly connected with the upper surface of the operating bedplate, a lifting mechanism is connected into the stand column, and the output end of the lifting mechanism is connected with a steering mechanism. The output end of the steering mechanism is connected with a transverse moving mechanism. According to the ultrasonic probe fixing device for the mouse experiment, by arranging the stand column, the lifting mechanism, the steering mechanism and the transverse moving mechanism between the operating bedplate and the probe body, when an ultrasonic treatment experiment needs to be conducted on a mouse, the position of the probe body can be fixed in an auxiliary mode through the stand column, the lifting mechanism, the steering mechanism and the transverse moving mechanism; meanwhile, up-down, acting and front-back six-direction adjustment can be achieved through the stand column, the lifting mechanism, the steering mechanism and the transverse moving mechanism, so that various treatment requirements are met.

Description

Technical Field

[0001] The invention relates to the technical field of ultrasonic probe fixing, in particular to an ultrasonic probe fixing device for mouse experiments. Background Art

[0002] Ultrasound imaging is a safe, non-invasive visualization technology that can provide real-time images of internal organs and structures and is widely used in medical research and clinical diagnosis. In recent years, low-intensity pulsed ultrasound technology that uses ultrasound to achieve therapeutic effects has been emerging, and this technology often uses ultrasound probes.

[0003] The use of ultrasound probes in low-intensity pulsed ultrasound treatment experiments on mice is for non-invasive treatment. Currently, when conducting mouse experiments, the mice are usually anesthetized and tied to the operating table, then a coupling agent is applied to the mouse's skin, and then the ultrasound probe is placed against the mouse's skin to achieve the purpose of treating the mouse.

[0004] During the mouse experiment, the operator held the probe to treat the mice. However, when performing long-term continuous treatment on mice, holding the probe may cause hand fatigue, making it impossible to accurately irradiate the target area. Summary of the invention

[0005] In view of the deficiencies in the prior art, the present invention provides an ultrasonic probe fixing device for mouse experiments, which can fix the probe body more accurately and stably.

[0006] To achieve the above-mentioned objectives, the present invention provides the following technical solutions: an ultrasonic probe fixing device for mouse experiments, comprising a column installed between an operating table and a probe body, the lower end of the column being fixedly connected to the upper surface of the operating table, the interior of the column being connected with a lifting mechanism, the output end of the lifting mechanism being connected with a steering mechanism, the output end of the steering mechanism being connected with a lateral movement mechanism, the output end of the lateral movement mechanism being connected to an end of the probe body away from the operating table, the end of the lifting mechanism located inside the column being connected with a toggle assembly, the outside of the upper end of the column being connected with a supporting U-shaped frame, the middle part of the supporting U-shaped frame being connected with a rotating assembly, the end of the toggle assembly away from the column being connected to an end of the rotating assembly located in the middle of the supporting U-shaped frame, the end of the rotating assembly away from the supporting U-shaped frame being connected to an adaptive assembly, the other end of the adaptive assembly being connected to a reversing assembly, one end of the reversing assembly being connected to a cleaning assembly, and the other end of the reversing assembly being also connected to the supporting U-shaped frame.

[0007] Furthermore, the lifting mechanism includes a lifting screw and a lifting motor. A lifting opening is opened on the side of the column close to the operating table. The outer wall of the lifting motor is fixedly connected to the outer wall of the upper end of the column. The output shaft of the lifting motor is fixedly connected to the upper end of the lifting screw. The lower end of the lifting screw passes through the column and the lifting opening, and the outer wall of the lifting screw is rotatably connected to the penetration point of the column. One end of the lifting screw located in the lifting opening is connected to the steering mechanism.

[0008] Furthermore, the steering mechanism includes a slider, an extended U-shaped frame, a steering motor and a movable plate. A sliding port connected to the lifting port is opened on the side of the column away from the operating table. One end of the extended U-shaped frame is fixedly connected to one side of the slider. The outer wall of the slider is slidably connected to the inner wall of the sliding port. The end of the extended U-shaped frame located in the lifting port is sleeved and threadedly connected to the outer wall of the lifting screw rod, and the end of the extended U-shaped frame located in the lifting port is also connected to the toggle assembly. The end of the extended U-shaped frame away from the sliding port is fixedly connected to the outer wall of the steering motor, the output shaft of the steering motor is fixedly connected to the outer wall of one end of the movable plate, and the interior of the movable plate is connected to the lateral moving mechanism.

[0009] Furthermore, the lateral moving mechanism includes a moving motor, a moving screw and a moving block. A moving opening is opened on the bottom surface of the moving plate. The outer wall of the moving motor is fixedly connected to the outer wall of the moving plate near one end of the steering motor. The output shaft of the moving motor is fixedly connected to one end of the moving screw. The other end of the moving screw passes through the moving plate, the moving block and the moving opening. The outer wall of the moving screw is rotatably connected to the penetration point of the moving plate. The outer wall of the moving screw is threadedly connected to the penetration point of the moving block. The outer wall of the moving block is slidably connected to the inner wall of the moving opening. The bottom surface of the moving block is fixedly connected to the upper end of the probe body.

[0010] Furthermore, the toggle assembly includes a toggle ring, a No. 1 anti-slip ring, two guide rails and two toggle blocks. The bottom surface of the extended U-shaped frame at one end inside the lifting port is provided with a No. 1 anti-slip opening. The outer wall of the No. 1 anti-slip ring is rotatably connected to the inner wall of the No. 1 anti-slip opening. The bottom surface of the No. 1 anti-slip ring is fixedly connected to the upper surface of the toggle ring. The side wall of the toggle ring is fixedly connected to one end of the two toggle blocks. The other ends of the two toggle blocks are both connected to the rotating assembly. The side wall of the toggle ring is provided with two guide openings. The side walls of the two guide rails are both fixedly connected to the inner wall of the lifting port. The inner walls of the two guide openings are respectively slidably connected to the outer walls of the two guide rails. The lower ends of the two guide rails are straight rails, and the upper ends of the two guide rails are inclined rails.

[0011] Furthermore, the rotating assembly includes a rotating rod, a force block and a long strip, one end of the long strip is sleeved and fixedly connected to the middle part of the rotating rod, the two ends of the rotating rod respectively pass through the upper and lower sides of the middle part of the supporting U-shaped frame, and the outer wall of the rotating rod is rotatably connected to the inner wall of the supporting U-shaped frame at the penetration point, the end of the long strip close to the rotating rod is fixedly connected to one end of the force block, the other end of the force block is located between the two shift blocks, and is matched and abutted against the two shift blocks, and the end of the long strip away from the rotating rod is connected to the adaptive assembly.

[0012] Furthermore, the adaptive component includes a rectangular rod, an elliptical block, a horizontal push spring, a vertical push spring and an extrusion rod. A spring cavity No. 1 is provided at the end of the long plate away from the rotating rod. One end of the horizontal push spring is fixedly connected to the inner wall of the No. 1 spring cavity, and the other end of the horizontal push spring is fixedly connected to one end of the rectangular rod. The other end of the rectangular rod passes through the No. 1 spring cavity and is fixedly connected to the middle part of the elliptical block. The middle part of the other side of the elliptical block is connected to one end of the reversing component close to the cleaning component. A spring cavity No. 2 is provided at the lower end of the elliptical block. The upper end of the vertical push spring is fixedly connected to the inner wall of the No. 2 spring cavity, the lower end of the vertical push spring is fixedly connected to the upper end of the extrusion rod, and the lower end of the extrusion rod passes through the No. 2 spring cavity and is connected to one end of the reversing component close to the supporting U-shaped frame.

[0013] Furthermore, the reversing assembly includes a fan-shaped frame, a fan-shaped plate, a fan-shaped rack plate, a gear and a No. 2 anti-slip ring, one end of the fan-shaped plate is fixedly connected to the upper side of the middle part of the supporting U-shaped frame, the other end of the fan-shaped plate is fixedly connected to the side wall of the fan-shaped rack plate, both ends of the fan-shaped frame are fixedly connected to the lower side of the middle part of the supporting U-shaped frame, the upper surface of the middle part of the fan-shaped frame is provided with a connected inner groove and an outer groove, one side of the gear is connected to the cleaning assembly, and the other side of the gear is provided with a No. 2 anti-slip opening, one end of the No. 2 anti-slip ring is fixedly connected to the side of the elliptical block away from the rectangular rod, the outer wall of the other end of the No. 2 anti-slip ring is rotatably connected to the inner wall of the No. 2 anti-slip opening, the gear is meshed with the fan-shaped rack plate, the outer wall of the extrusion rod away from one end of the vertical push spring is located in the inner groove and the outer groove, and the outer wall of the extrusion rod is slidably connected to the inner walls of the inner groove and the outer groove.

[0014] Furthermore, the cleaning assembly includes a mounting plate, a center block and a plurality of wiping assemblies, one side of the center block is fixedly connected to the side of the gear away from the second anti-slip ring, the other end of the center block is fastened to the mounting plate by bolts, and the plurality of wiping assemblies are located between the mounting plate and the center block, and the plurality of wiping assemblies are matched with the probe body and offset against each other.

[0015] Furthermore, the wiping assembly includes wiping cotton, a support plate and a plurality of limit strips, a plurality of limit openings are opened on the side wall of the center block, one side of the support plate is fixedly connected to one side of the wiping cotton, the other side of the wiping cotton is against the bottom surface of the probe body, the side of the support plate away from the wiping cotton is fixedly connected to one side of the plurality of limit strips, and the outer walls of the plurality of limit strips are respectively slidably connected to the inner walls of the plurality of limit openings.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] 1. This kind of ultrasound probe fixing device for mouse experiments, by arranging a column, a lifting mechanism, a steering mechanism and a lateral moving mechanism between the operating table and the probe body, can assist in fixing the position of the probe body through the column, the lifting mechanism, the steering mechanism and the lateral moving mechanism when it is necessary to conduct ultrasound treatment experiments on mice, and can also achieve six-way adjustment of up and down, action, front and back through the column, the lifting mechanism, the steering mechanism and the lateral moving mechanism to meet various treatment needs.

[0018] 2. The ultrasonic probe fixing device for mouse experiments has a toggle assembly disposed below the steering mechanism, and a supporting U-shaped frame, a rotating assembly and a cleaning assembly disposed outside the column. When the steering mechanism is about to rise to the top of the column following the lifting mechanism, the toggle assembly can rotate the rotating assembly and the cleaning assembly, thereby wiping and cleaning the coupling agent adhered to the surface of the probe body, which is not only cleaner and more hygienic, but also saves the steps of manual operation.

[0019] 3. This kind of ultrasound probe fixing device for mouse experiments has a reversing component between the rotating component and the cleaning component. After the cleaning component wipes and cleans the coupling agent on the surface of the probe body, it can automatically control the rotation of the cleaning component, and then turn away the side that has been wiped with the coupling agent and is contaminated, and then turn up the clean side to facilitate secondary use without manual operation, which is more convenient and easy.

[0020] 4. The ultrasonic probe fixing device for mouse experiments, by setting an adaptive component between the reversing component and the rotating component, can prevent the dirtier side that has been repositioned from being turned back again when the cleaning component follows the rotating component to return to its original position after the reversing component automatically controls the reversal of the cleaning component. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the overall appearance of the present invention;

[0022] Figure 2 This is a schematic diagram of the overall appearance of the present invention from another viewing angle;

[0023] Figure 3 It is a detailed connection diagram of the lifting mechanism, steering mechanism and lateral movement mechanism of the present invention;

[0024] Figure 4 For the present invention Figure 3 The enlarged schematic diagram of point A in the middle;

[0025] Figure 5 For the present invention Figure 3The enlarged schematic diagram of point B in the middle;

[0026] Figure 6 It is a detailed connection diagram of the components such as the toggle assembly, the rotating assembly and the cleaning assembly of the present invention;

[0027] Figure 7 For the present invention Figure 6 A schematic diagram of each component from another perspective;

[0028] Figure 8 It is a detailed connection diagram of the cleaning component of the present invention;

[0029] Fig. 9 It is a detailed appearance schematic diagram of the supporting U-shaped frame and some parts of the reversing assembly of the present invention;

[0030] Fig.10 For the present invention Fig. 9 The enlarged schematic diagram of the center C;

[0031] Fig.11 It is a detailed connection diagram of the rotating assembly and the adaptive assembly of the present invention;

[0032] Fig.12 For the present invention Fig.11 Enlarged schematic diagram of point D in the middle.

[0033] In the figure: 1. operating table; 2. upright column; 3. lifting screw rod; 4. supporting U-shaped frame; 5. lifting motor; 6. extending U-shaped frame; 7. steering motor; 8. moving plate; 9. probe body; 10. moving motor; 11. mounting plate; 12. wiping cotton; 13. slider; 14. sliding mouth; 15. fan-shaped frame; 16. inner groove; 17. fan-shaped plate; 18. fan-shaped rack plate; 19. rotating rod; 20. moving mouth; 21. moving screw rod; 22. guide rail; 23. lifting mouth; 24. moving Block; 25, No. 1 anti-slip opening; 26, toggle ring; 27, guide opening; 28, toggle block; 29, force block; 30, long strip; 31, rectangular rod; 32, elliptical block; 33, gear; 34, support plate; 35, center block; 36, No. 1 anti-slip ring; 37, outer groove; 38, limit strip; 39, limit opening; 40, No. 2 anti-slip ring; 41, No. 2 anti-slip opening; 42, No. 1 spring cavity; 43, horizontal push spring; 44, vertical push spring; 45, extrusion rod; 46, No. 2 spring cavity. DETAILED DESCRIPTION

[0034] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0035] See also Figure 1-Figure 12, a device for fixing an ultrasonic probe for mouse experiments, comprising a column 2 installed between an operating table 1 and a probe body 9, the lower end of the column 2 being fixedly connected to the upper surface of the operating table 1, the interior of the column 2 being connected with a lifting mechanism, the output end of the lifting mechanism being connected with a steering mechanism, the output end of the steering mechanism being connected with a lateral movement mechanism, the output end of the lateral movement mechanism being connected with an end of the probe body 9 away from the operating table 1, the end of the lifting mechanism located inside the column 2 being connected with a toggle assembly, the outside of the upper end of the column 2 being connected with a supporting U-shaped frame 4, the middle part of the supporting U-shaped frame 4 being connected with a rotating assembly, the end of the toggle assembly away from the column 2 being connected with an end of the rotating assembly located in the middle of the supporting U-shaped frame 4, the end of the rotating assembly away from the supporting U-shaped frame 4 being connected with an adaptive assembly, the other end of the adaptive assembly being connected with a reversing assembly, one end of the reversing assembly being connected with a cleaning assembly, and the other end of the reversing assembly being also connected to the supporting U-shaped frame 4.

[0036] like Figures 1 to 12 As shown, the ultrasonic probe fixing device for mouse experiments in the present invention can be used according to the following steps:

[0037] 1. First, fix the anesthetized mouse on the surface of the operating table 1 through an external binding fixing structure, then apply a coupling agent to the skin of the mouse that needs ultrasound treatment, then set the relevant data of the probe body 9 through an external controller, and then control the drive of each motor separately through a remote controller (or control panel), preferably a rocker controller for easy operation;

[0038] 2. When the probe body 9 needs to be raised or lowered, the lifting mechanism can be turned on by the remote control. After the lifting mechanism is started, the steering mechanism can be moved up and down inside the column 2. During the up and down movement of the steering mechanism, the toggle assembly near one end of the column 2, the lateral movement mechanism at the other end and the probe body 9 connected to the lateral movement mechanism can be lifted or lowered together, so that the height of the probe body 9 can be changed at will.

[0039] 3. When the probe body 9 needs to be controlled to move to one side (for example, from the chest of the mouse to the head), the steering mechanism only needs to be turned on by the remote control. After the steering mechanism is turned on, the lateral moving mechanism can be controlled to rotate with the steering mechanism as the axis, thereby changing the angular position of the lateral moving mechanism and the probe body 9 on the operating table 1. Then, the lateral moving mechanism is turned on by the remote control. After the lateral moving mechanism is turned on, the output end will translate the probe body 9 inside the steering mechanism, thereby controlling the probe body 9 to radiate a circle with the steering mechanism as the center (for example, Figure 1 The circular area on the operating table 1 in the middle) can therefore be used to perform ultrasound treatment at various angles on the mice within the circle;

[0040] 4. When doing experiments on mice, the mice often need to change their body position, for example, from supine to lateral position. In this case, after ultrasound treatment of the skin on the front side of the mouse, the ultrasound treatment needs to be stopped, and then the body position of the mouse needs to be changed manually;

[0041] 5. When the ultrasonic treatment is stopped, the remote controller is reset to zero. At this time, the transverse movement mechanism and the steering mechanism will move the probe body 9 back to the original position (i.e. facing the center of the operating table 1). Then the lifting mechanism controls the steering mechanism to rise. When the steering mechanism rises, it will bring the toggle assembly that originally descended with it to rise together. When the steering mechanism is about to rise to the top of the column 2, the toggle assembly is just located between the rotating assemblies supporting the U-shaped frame 4. Then, as the toggle assembly continues to rise with the steering mechanism, it will automatically and instantly deflect. At the moment of the toggle assembly deflection, the rotating assembly will be toggled to one side.

[0042] 6. After the rotating assembly is turned, it will rotate to one side with the adaptive assembly, the reversing assembly and the cleaning assembly connected to the other end. At the moment when the cleaning assembly rotates, it will wipe the surface of the probe body 9 that is rising with the steering mechanism, so as to wipe off the coupling agent adhering to the surface of the probe body 9;

[0043] 7. After the cleaning component wipes off the coupling agent on the surface of the probe body 9, the cleaning component has completely moved from one side of the probe body 9 to the other side of the probe body 9, and the steering mechanism, the toggle assembly and the probe body 9 continue to rise. At the same time, after the cleaning component cleans off the coupling agent on the surface of the probe body 9, it will continue to rotate under the toggle of the toggle assembly. At this time, the reversing assembly connected to the cleaning component will gradually control the cleaning component to rotate to one side, so that the side of the cleaning component that has just been in contact with the probe body 9 and has been contaminated by the coupling agent can be turned away. The side that is turned up is still a clean side, and the coupling agent on the surface of the probe body 9 can be wiped by the next side.

[0044] 8. After the reversing component controls the cleaning component to reversing, the two parts of the reversing component are separated due to the effect of the adaptive component, and at the same time, the steering mechanism and the probe body 9 have risen to the uppermost end of the column 2. At this time, the entire device stops running, and then the operator changes the body position of the mouse and continues to fix it after the change. When a second treatment is required after fixation, the lifting mechanism, steering mechanism and lateral movement mechanism are started in the same way as above;

[0045] 9. When the lifting mechanism descends again, the toggle assembly will reverse and push the rotating assembly back to its original position. At this time, because the coupling agent on the surface of the probe body 9 has been wiped off before, the clean side that has been switched over will not be contaminated, and the cleaning assembly will return to its previous form. After the probe body 9 rises again, the surface of the probe body 9 can be cleaned.

[0046] Special mention should be made here:

[0047] 1. The external controller, remote control and control panel mentioned above are all existing mature technologies, so they will not be described in detail here;

[0048] 2. The mouse body position is generally divided into at least four situations: supine position, prone position and two lateral positions, so the cleaning component needs to be set to be able to change directions at least four times;

[0049] 3. Because the two parts of the reversing assembly are separated, when the rotating assembly returns to its original position, it will not rotate with the cleaning assembly again, so it will not affect the subsequent wiping of the coupling agent on the surface of the probe body 9.

[0050] As a preferred solution of the present invention, the lifting mechanism includes a lifting screw 3 and a lifting motor 5. A lifting opening 23 is opened on the side of the column 2 close to the operating table 1. The outer wall of the lifting motor 5 is fixedly connected to the outer wall of the upper end of the column 2. The output shaft of the lifting motor 5 is fixedly connected to the upper end of the lifting screw 3. The lower end of the lifting screw 3 passes through the column 2 and the lifting opening 23, and the outer wall of the lifting screw 3 is rotatably connected to the penetration point of the column 2. The end of the lifting screw 3 located in the lifting opening 23 is connected to the steering mechanism.

[0051] More specifically, when it is necessary to control the probe body 9 to rise, it is only necessary to turn on the switch of the lifting motor 5 through the remote control, and then the output shaft of the lifting motor 5 can drive the lifting screw rod 3 to rotate. After the lifting screw rod 3 rotates, it can drive the steering mechanism located in the lifting port 23 to realize lifting and lowering along the lifting port 23.

[0052] As a preferred embodiment of the present invention, the steering mechanism includes a slider 13, an extended U-shaped frame 6, a steering motor 7 and a movable plate 8. A sliding port 14 connected to a lifting port 23 is provided on a side of the column 2 away from the operating table 1. One end of the extended U-shaped frame 6 is fixedly connected to one side of the slider 13. The outer wall of the slider 13 is slidably connected to the inner wall of the sliding port 14. One end of the extended U-shaped frame 6 located in the lifting port 23 is sleeved and threadedly connected to the outer wall of the lifting screw rod 3, and the end of the extended U-shaped frame 6 located in the lifting port 23 is also connected to the toggle assembly. The end of the extended U-shaped frame 6 away from the sliding port 14 is fixedly connected to the outer wall of the steering motor 7. The output shaft of the steering motor 7 is fixedly connected to the outer wall of one end of the movable plate 8, and the interior of the movable plate 8 is connected to the lateral moving mechanism.

[0053] More specifically, when the lifting screw 3 rotates, the extended U-shaped frame 6 will not rotate due to the restrictions of the slider 13 and the sliding mouth 14, so the extended U-shaped frame 6 will only move up and down along the lifting screw 3, and as the extended U-shaped frame 6 rises and falls, the steering motor 7 and the moving plate 8 at the other end of the extended U-shaped frame 6 can be lifted and lowered together.

[0054] In addition, when it is necessary to control the lateral moving mechanism to rotate, it is only necessary to turn on the switch of the steering motor 7 through the remote control, and the output shaft of the steering motor 7 can rotate the moving plate 8, thereby rotating the lateral moving mechanism connected to the moving plate 8.

[0055] As a preferred embodiment of the present invention, the lateral moving mechanism includes a moving motor 10, a moving screw 21 and a moving block 24. A moving opening 20 is opened on the bottom surface of the moving plate 8. The outer wall of the moving motor 10 is fixedly connected to the outer wall of the moving plate 8 near the steering motor 7. The output shaft of the moving motor 10 is fixedly connected to one end of the moving screw 21. The other end of the moving screw 21 passes through the moving plate 8, the moving block 24 and the moving opening 20. The outer wall of the moving screw 21 is rotatably connected to the penetration point of the moving plate 8. The outer wall of the moving screw 21 is threadedly connected to the penetration point of the moving block 24. The outer wall of the moving block 24 is slidably connected to the inner wall of the moving opening 20. The bottom surface of the moving block 24 is fixedly connected to the upper end of the probe body 9.

[0056] More specifically, when the movable plate 8 rotates following the steering motor 7, the movable motor 10, movable screw 21 and movable block 24 connected to the movable plate 8 can rotate together, thereby changing the position of the probe body 9 connected to the movable block 24 above the operating table 1.

[0057] In addition, when it is necessary to control the probe body 9 to further change its position on the operating table 1, it is only necessary to turn on the moving motor 10 through the remote control, and the output shaft of the moving motor 10 can drive the moving screw 21 to rotate. After that, the moving screw 21 rotates to cause the moving block 24 located in the moving opening 20 to move, thereby further changing the position of the probe body 9 above the operating table 1.

[0058] As a preferred embodiment of the present invention, the toggle assembly includes a toggle ring 26, a No. 1 anti-slip ring 36, two guide rails 22 and two toggle blocks 28. The bottom surface of the extended U-shaped frame 6 located at one end inside the lifting port 23 is provided with a No. 1 anti-slip opening 25. The outer wall of the No. 1 anti-slip ring 36 is rotatably connected to the inner wall of the No. 1 anti-slip opening 25. The bottom surface of the No. 1 anti-slip ring 36 is fixedly connected to the upper surface of the toggle ring 26. The side wall of the toggle ring 26 is fixedly connected to one end of the two toggle blocks 28. The other ends of the two toggle blocks 28 are both connected to the rotating assembly. The side wall of the toggle ring 26 is provided with two guide openings 27. The side walls of the two guide rails 22 are both fixedly connected to the inner wall of the lifting port 23. The inner walls of the two guide openings 27 are respectively slidably connected to the outer walls of the two guide rails 22. The lower ends of the two guide rails 22 are straight rails, and the upper ends of the two guide rails 22 are inclined rails.

[0059] More specifically, when the extended U-shaped frame 6 is raised or lowered, due to the action of the No. 1 anti-slip ring 36 and the No. 1 anti-slip opening 25, the toggle ring 26 will follow the extended U-shaped frame 6 to achieve lifting and lowering, and because the lower ends of the two guide rails 22 are straight rails, the toggle ring 26 will not rotate when following the extended U-shaped frame 6 to be lifted or lowered, thereby preventing the two toggle blocks 28 from being offset from the alignment position of the rotating assembly.

[0060] When the extended U-shaped frame 6 is about to rise to the top of the lifting port 23 with the toggle ring 26, the toggle ring 26 moves to the position of the inclined rail at the upper end of the two guide rails 22. At this time, due to the restrictions of the inclined rail and the guide port 27, the toggle ring 26 will passively rotate to one side. When the toggle ring 26 rotates, it can rotate in the same direction with the two toggle blocks 28. After the two toggle blocks 28 rotate, they can push the rotating assembly located in the supporting U-shaped frame 4 to rotate instantly, thereby achieving the above-mentioned purpose of cleaning the probe body 9.

[0061] On the contrary, when the toggle ring 26 follows the extended U-shaped frame 6 to descend, the toggle ring 26 will rotate in the opposite direction, and then the rotating assembly can be pushed back to the original position by the shifting block 28 again.

[0062] As a preferred solution of the present invention, the rotating assembly includes a rotating rod 19, a force block 29 and a long plate 30, one end of the long plate 30 is sleeved and fixedly connected to the middle part of the rotating rod 19, the two ends of the rotating rod 19 respectively pass through the upper and lower sides of the middle part of the supporting U-shaped frame 4, and the outer wall of the rotating rod 19 is rotatably connected to the inner wall of the supporting U-shaped frame 4 at the penetration point, the end of the long plate 30 close to the rotating rod 19 is fixedly connected to one end of the force block 29, the other end of the force block 29 is located between the two shift blocks 28, and matches and abuts against the two shift blocks 28, and the end of the long plate 30 away from the rotating rod 19 is connected to the adaptive assembly.

[0063] More specifically, when the toggle ring 26 rises to the position of the inclined rail, the two toggle blocks 28 will rotate along with the toggle ring 26, and when the toggle blocks 28 rotate, they will push the force-bearing block 29 in the middle to rotate to one side. After the force-bearing block 29 is subjected to force, it will immediately cause the long plate 30 to rotate with the rotating rod 19 as the axis, thereby causing the adaptive component, the reversing component and the cleaning component at the other end of the long plate 30 to rotate together.

[0064] It should be noted that the rotation between the rotating rod 19 and the supporting U-shaped frame 4 has a certain friction force, and it is not easy to rotate without the thrust of the shifting block 28 and the force-bearing block 29.

[0065] As a preferred embodiment of the present invention, the adaptive component includes a rectangular rod 31, an elliptical block 32, a horizontal push spring 43, a vertical push spring 44 and an extrusion rod 45. A spring cavity 42 is provided at one end of the long plate 30 away from the rotating rod 19. One end of the horizontal push spring 43 is fixedly connected to the inner wall of the spring cavity 42. The other end of the horizontal push spring 43 is fixedly connected to one end of the rectangular rod 31. The other end of the rectangular rod 31 passes through the spring cavity 42 and is fixedly connected to the middle part of the elliptical block 32. The middle part of the other side of the elliptical block 32 is connected to one end of the reversing component close to the cleaning component. A spring cavity 46 is provided at the lower end of the elliptical block 32. The upper end of the vertical push spring 44 is fixedly connected to the inner wall of the spring cavity 46. The lower end of the vertical push spring 44 is fixedly connected to the upper end of the extrusion rod 45. The lower end of the extrusion rod 45 passes through the spring cavity 46 and is connected to one end of the reversing component close to the supporting U-shaped frame 4.

[0066] More specifically, when the long strip 30 rotates, the horizontal push spring 43 and the rectangular rod 31 located in the No. 1 spring chamber 42 will rotate together, and then the rectangular rod 31 will rotate with the elliptical block 32, and the elliptical block 32 will rotate with the cleaning assembly, the vertical push spring 44 and the extrusion rod 45. During the rotation process, the extrusion rod 45 will move on the surface of the reversing assembly, thereby realizing the disconnection and merging of the reversing assembly.

[0067] As a preferred embodiment of the present invention, the reversing assembly includes a sector frame 15, a sector plate 17, a sector rack plate 18, a gear 33 and a second anti-slip ring 40, one end of the sector plate 17 is fixedly connected to the upper side of the middle part of the support U-shaped frame 4, the other end of the sector plate 17 is fixedly connected to the side wall of the sector rack plate 18, both ends of the sector frame 15 are fixedly connected to the lower side of the middle part of the support U-shaped frame 4, the upper surface of the middle part of the sector frame 15 is provided with a connected inner groove 16 and an outer groove 37, one side of the gear 33 Connected to the cleaning component, a No. 2 anti-slip opening 41 is opened on the other side of the gear 33, one end of the No. 2 anti-slip ring 40 is fixedly connected to the side of the elliptical block 32 away from the rectangular rod 31, the outer wall of the other end of the No. 2 anti-slip ring 40 is rotatably connected to the inner wall of the No. 2 anti-slip opening 41, the gear 33 is meshed with the fan-shaped rack plate 18, the outer wall of the extrusion rod 45 away from the end of the vertical push spring 44 is located in the inner groove 16 and the outer groove 37, and the outer wall of the extrusion rod 45 is slidably connected to the inner walls of the inner groove 16 and the outer groove 37.

[0068] More specifically, when the long plate 30 rotates, the gear 33 will follow the elliptical block 32 to rotate with the rotating rod 19 as the axis, and the cleaning component connected to the other side of the gear 33 will wipe the coupling agent on the surface of the probe body 9. When the cleaning component has completed wiping the coupling agent on the surface of the probe body 9 and the cleaning component has passed through the position of the probe body 9, the gear 33 is just meshed with the fan-shaped rack plate 18. Therefore, the gear 33 will follow the rotation of the rotating rod 19, and the gear 33 itself will also rotate with the No. 2 anti-slip ring 40 and the No. 2 anti-slip port 41. After the gear 33 rotates, the cleaning component connected to the other side of the gear 33 can rotate together, thereby realizing the reversal of the cleaning component.

[0069] When the gear 33 and the elliptical block 32 rotate with the rotating rod 19 as the axis, the bottom surface of the extrusion rod 45 connected to the lower end of the elliptical block 32 will abut against the inner wall of the outer groove 37 and move from one end of the outer groove 37 to the other end. There is a height difference between the other end of the outer groove 37 and the inner groove 16, and the distance between the extrusion rod 45 and the inner groove 16 is greater than the width of the teeth of the rack plate 18. Therefore, when the reversing assembly reverses the cleaning assembly, the gear 33 and the fan-shaped rack plate 18 are disengaged. After that, the gear 33 and the elliptical block 32 continue to rotate a distance with the rotating rod 19 as the axis. When the extended U-shaped frame 6 rises to the top of the lifting port 23, the toggle ring 26 stops rotating. Therefore, the gear 33 and the elliptical block 32 will also stop rotating at this time, and at the same time, the extrusion rod 45 just moves from the position of the outer groove 37 to the top of the inner groove 16, and then the extrusion rod 45 will instantly fall and be squeezed on the inner wall of the inner groove 16 under the action of the vertical push spring 44.

[0070] When the toggle ring 26 rotates in the opposite direction with the gear 33 and the elliptical block 32, the extrusion rod 45 will not enter the outer groove 37 again because of the height difference between the inner groove 16 and the outer groove 37, and then follow the gear 33 and the elliptical block 32 to slide in the inner groove 16. Because the inner groove 16 is located close to the direction of the supporting U-shaped frame 4, the gear 33 will not mesh with the fan-shaped rack plate 18 when moving along the inner groove 16, so it will not cause the gear 33 to rotate, nor will it cause the cleaning assembly to return to its original position.

[0071] When the extrusion rod 45 moves along the inner groove 16 to the other end, the height of the inner groove 16 at this end is higher than the height of the outer groove 37. Therefore, the extrusion rod 45 will fall into the outer groove 37 under the action of the transverse push spring 43. When the surface of the probe body 9 needs to be cleaned again, the extrusion rod 45 will push the gear 33 and the elliptical block 32 to move from the outer groove 37 to achieve normal engagement between the gear 33 and the fan-shaped rack plate 18.

[0072] Special mention should be made here:

[0073] 1. During the mouse experiment, the body position may need to be changed several times. The gear 33 and the sector rack plate 18 with the appropriate number of teeth can be selected according to the number of times the mouse needs to change its body position. For example, if the mouse needs to be treated in four body positions, the number of teeth of the gear 33 can be four times that of the sector rack plate 18, so that after the gear 33 is meshed with the sector rack plate 18, the gear 33 will rotate exactly one quarter;

[0074] 2. The interior of the outer groove 37 and the inner groove 16 are both sloped surfaces, that is, the extrusion rod 45 will gradually rise when moving along the outer groove 37 or the inner groove 16. Therefore, when the extrusion rod 45 moves from one end of the outer groove 37 and the inner groove 16 to the other end, it will fall into a lower groove.

[0075] As a preferred solution of the present invention, the cleaning assembly includes a mounting plate 11, a center block 35 and a plurality of wiping assemblies, one side of the center block 35 is fixedly connected to the side of the gear 33 away from the second anti-slip ring 40, and the other end of the center block 35 is fastened to the mounting plate 11 by bolts, and the plurality of wiping assemblies are located between the mounting plate 11 and the center block 35, and the plurality of wiping assemblies are matched with the probe body 9 and offset against each other.

[0076] More specifically, when the gear 33 rotates along with the rotating rod 19 , the mounting plate 11 , the center block 35 and the plurality of wiping components will rotate together, and the coupling agent on the surface of the probe body 9 can be wiped and cleaned by the wiping components during the movement.

[0077] When the gear 33 itself rotates, it will also rotate with the mounting plate 11, the center block 35 and a plurality of wiping components connected thereto, thereby achieving a reversing effect.

[0078] It should be particularly noted here that the central block 35 and the mounting plate 11 are fastened together by bolts, so that the wiping assembly can be disassembled by the bolts when it is necessary to replace the wiping assembly.

[0079] As a preferred embodiment of the present invention, the wiping assembly includes a wiping cotton 12, a support plate 34 and a plurality of limit strips 38. The side wall of the center block 35 is provided with a plurality of limit openings 39. One side of the support plate 34 is fixedly connected to one side of the wiping cotton 12, and the other side of the wiping cotton 12 is abutted against the bottom surface of the probe body 9. The side of the support plate 34 away from the wiping cotton 12 is fixedly connected to one side of the plurality of limit strips 38, and the outer walls of the plurality of limit strips 38 are slidably connected to the inner walls of the plurality of limit openings 39 respectively.

[0080] More specifically, when the gear 33 rotates along with the rotating rod 19 , the wiping cotton 12 , the supporting plate 34 and the plurality of limiting strips 38 rotate together.

[0081] In addition, the limiting opening 39 and the limiting strip 38 can ensure the connection stability between the support plate 34 and the wiping cotton 12, and when the wiping cotton 12 needs to be cleaned or replaced, the support plate 34 and the wiping cotton 12 can be more smoothly pulled off the center block 35 after the mounting plate 11 is removed.

[0082] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A device for fixing an ultrasonic probe for mouse experiments, comprising a column (2) installed between an operating table (1) and a probe body (9), characterized in that: The lower end of the column (2) is fixedly connected to the upper surface of the operating table (1); the interior of the column (2) is connected to a lifting mechanism; the output end of the lifting mechanism is connected to a steering mechanism; the output end of the steering mechanism is connected to a lateral movement mechanism; the output end of the lateral movement mechanism is connected to an end of the probe body (9) away from the operating table (1); the end of the lifting mechanism located inside the column (2) is connected to a toggle assembly; the exterior of the upper end of the column (2) is connected to a support U-shaped frame (4); the middle of the support U-shaped frame (4) is connected to a rotating assembly; the end of the toggle assembly away from the column (2) is connected to an end of the rotating assembly located in the middle of the support U-shaped frame (4); the end of the rotating assembly away from the support U-shaped frame (4) is connected to an adaptive assembly; the other end of the adaptive assembly is connected to a reversing assembly; one end of the reversing assembly is connected to a cleaning assembly; the other end of the reversing assembly is also connected to the support U-shaped frame (4).

2. The ultrasonic probe fixing device for mouse experiments according to claim 1, characterized in that: The lifting mechanism comprises a lifting screw (3) and a lifting motor (5); a lifting opening (23) is provided on one side of the column (2) close to the operating table (1); the outer wall of the lifting motor (5) is fixedly connected to the outer wall of the upper end of the column (2); the output shaft of the lifting motor (5) is fixedly connected to the upper end of the lifting screw (3); the lower end of the lifting screw (3) passes through the column (2) and the lifting opening (23); the outer wall of the lifting screw (3) is rotatably connected to the penetration point of the column (2); and one end of the lifting screw (3) located in the lifting opening (23) is connected to the steering mechanism.

3. The ultrasonic probe fixing device for mouse experiments according to claim 2, characterized in that: The steering mechanism comprises a slider (13), an extended U-shaped frame (6), a steering motor (7) and a moving plate (8); a sliding port (14) communicating with a lifting port (23) is provided on a side of the column (2) away from the operating table (1); one end of the extended U-shaped frame (6) is fixedly connected to one side of the slider (13); the outer wall of the slider (13) is slidably connected to the inner wall of the sliding port (14); one end of the extended U-shaped frame (6) located in the lifting port (23) is sleeved and threadedly connected to the outer wall of the lifting screw rod (3); and the end of the extended U-shaped frame (6) located in the lifting port (23) is also connected to the toggle assembly; one end of the extended U-shaped frame (6) away from the sliding port (14) is fixedly connected to the outer wall of the steering motor (7); the output shaft of the steering motor (7) is fixedly connected to the outer wall of one end of the moving plate (8); and the interior of the moving plate (8) is connected to the transverse moving mechanism.

4. The ultrasonic probe fixing device for mouse experiments according to claim 3, characterized in that: The lateral movement mechanism comprises a moving motor (10), a moving screw rod (21) and a moving block (24); a moving opening (20) is provided on the bottom surface of the moving plate (8); an outer wall of the moving motor (10) is fixedly connected to an outer wall of one end of the moving plate (8) close to the steering motor (7); an output shaft of the moving motor (10) is fixedly connected to one end of the moving screw rod (21); the other end of the moving screw rod (21) passes through the moving plate (8), the moving block (24) and the moving opening (20); an outer wall of the moving screw rod (21) is rotatably connected to the through-hole of the moving plate (8); an outer wall of the moving screw rod (21) is threadedly connected to the through-hole of the moving block (24); an outer wall of the moving block (24) is slidably connected to an inner wall of the moving opening (20); and a bottom surface of the moving block (24) is fixedly connected to the upper end of the probe body (9).

5. The ultrasonic probe fixing device for mouse experiments according to claim 3 or 4, characterized in that: The toggle assembly comprises a toggle ring (26), a No. 1 anti-slip ring (36), two guide rails (22) and two toggle blocks (28); a No. 1 anti-slip opening (25) is provided on the bottom surface of one end of the extended U-shaped frame (6) located in the lifting opening (23); an outer wall of the No. 1 anti-slip ring (36) is rotatably connected to the inner wall of the No. 1 anti-slip opening (25); a bottom surface of the No. 1 anti-slip ring (36) is fixedly connected to the upper surface of the toggle ring (26); a side wall of the toggle ring (26) is connected to the One end of the two shifting blocks (28) is fixedly connected, and the other ends of the two shifting blocks (28) are connected to the rotating assembly. The side wall of the shifting ring (26) is provided with two guide openings (27). The side walls of the two guide rails (22) are fixedly connected to the inner wall of the lifting opening (23). The inner walls of the two guide openings (27) are respectively slidably connected to the outer walls of the two guide rails (22). The lower ends of the two guide rails (22) are straight rails, and the upper ends of the two guide rails (22) are inclined rails.

6. The ultrasonic probe fixing device for mouse experiments according to claim 5, characterized in that: The rotating assembly comprises a rotating rod (19), a force block (29) and a long strip (30); one end of the long strip (30) is sleeved and fixedly connected to the middle part of the rotating rod (19); the two ends of the rotating rod (19) respectively penetrate the upper and lower sides of the middle part of the supporting U-shaped frame (4); and the outer wall of the rotating rod (19) is rotatably connected to the inner wall of the supporting U-shaped frame (4) at the penetration point; one end of the long strip (30) close to the rotating rod (19) is fixedly connected to one end of the force block (29); the other end of the force block (29) is located between the two shifting blocks (28) and matches and abuts against the two shifting blocks (28); and one end of the long strip (30) away from the rotating rod (19) is connected to the adaptive assembly.

7. The ultrasonic probe fixing device for mouse experiments according to claim 6, characterized in that: The adaptive component comprises a rectangular rod (31), an elliptical block (32), a horizontal push spring (43), a vertical push spring (44) and an extrusion rod (45); a first spring cavity (42) is provided at one end of the long strip (30) away from the rotating rod (19); one end of the horizontal push spring (43) is fixedly connected to the inner wall of the first spring cavity (42); the other end of the horizontal push spring (43) is fixedly connected to one end of the rectangular rod (31); the other end of the rectangular rod (31) passes through the first spring cavity (42) and is connected to the elliptical block (32); The middle part of the block (32) is fixedly connected, the middle part of the other side of the elliptical block (32) is connected to one end of the reversing assembly close to the cleaning assembly, the lower end of the elliptical block (32) is provided with a second spring cavity (46), the upper end of the vertical push spring (44) is fixedly connected to the inner wall of the second spring cavity (46), the lower end of the vertical push spring (44) is fixedly connected to the upper end of the extrusion rod (45), the lower end of the extrusion rod (45) passes through the second spring cavity (46) and is connected to one end of the reversing assembly close to the supporting U-shaped frame (4).

8. The ultrasonic probe fixing device for mouse experiments according to claim 7, characterized in that: The reversing assembly comprises a sector frame (15), a sector plate (17), a sector rack plate (18), a gear (33) and a second anti-slip ring (40), one end of the sector plate (17) is fixedly connected to the upper side of the middle part of the supporting U-shaped frame (4), the other end of the sector plate (17) is fixedly connected to the side wall of the sector rack plate (18), both ends of the sector frame (15) are fixedly connected to the lower side of the middle part of the supporting U-shaped frame (4), the upper surface of the middle part of the sector frame (15) is provided with a communicating inner groove (16) and an outer groove (37), one side of the gear (33) is connected to the cleaning assembly A second anti-slip opening (41) is provided on the other side of the gear (33), one end of the second anti-slip ring (40) is fixedly connected to a side of the elliptical block (32) away from the rectangular rod (31), the outer wall of the other end of the second anti-slip ring (40) is rotatably connected to the inner wall of the second anti-slip opening (41), the gear (33) is meshed with the fan-shaped rack plate (18), the outer wall of the extrusion rod (45) away from the end of the vertical push spring (44) is located in the inner groove (16) and the outer groove (37), and the outer wall of the extrusion rod (45) is slidably connected to the inner walls of the inner groove (16) and the outer groove (37).

9. The ultrasonic probe fixing device for mouse experiments according to claim 8, characterized in that: The cleaning assembly comprises a mounting plate (11), a center block (35) and a plurality of wiping assemblies. One side of the center block (35) is fixedly connected to a side of the gear (33) away from the second anti-slip ring (40). The other end of the center block (35) is fastened to the mounting plate (11) by bolts. The plurality of wiping assemblies are located between the mounting plate (11) and the center block (35). The plurality of wiping assemblies are matched with the probe body (9) and abutted against each other.

10. The ultrasonic probe fixing device for mouse experiments according to claim 9, characterized in that: The wiping assembly comprises a wiping cotton (12), a support plate (34) and a plurality of limiting strips (38); a side wall of the central block (35) is provided with a plurality of limiting openings (39); one side of the support plate (34) is fixedly connected to one side of the wiping cotton (12); the other side of the wiping cotton (12) abuts against the bottom surface of the probe body (9); a side of the support plate (34) away from the wiping cotton (12) is fixedly connected to one side of the plurality of limiting strips (38); and the outer walls of the plurality of limiting strips (38) are respectively slidably connected to the inner walls of the plurality of limiting openings (39).

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