Constant-temperature storage device applied to chromosome FISH (fluorescence in situ hybridization) detection slide

Abstract

The invention relates to the technical field of slide preservation, and discloses a constant-temperature preservation device applied to chromosome FISH (fluorescence in situ hybridization) detection slides, which comprises a constant-temperature box, a plurality of suitcases, placement division bars, a bearing plate and a partition plate, according to the constant-temperature storage device applied to the chromosome FISH detection slides, the two rubber rollers are clamped on the two sides of the independent slide box, so that the independent slide box is fixed to the upper surface of the bearing plate, the independent slide box is very convenient to take and use, meanwhile, the inner walls of the two sides of the suitcase are each provided with a plurality of sets of placement division bars, and the placement division bars are convenient to use. At the moment, the edge blocks at the two ends of the bearing plate can be placed on the upper surfaces of the placing division bars, so that the multiple sets of placing division bars can be stacked, a large amount of space is saved, meanwhile, the independent slide boxes are convenient to find, the two sides of the suitcase have the storage and taking functions, and the finding efficiency is higher when the independent slide boxes are taken.

Description

Technical Field

[0001] The invention relates to the technical field of glass slide preservation, in particular to a constant temperature preservation device applied to chromosome FISH detection glass slides. Background Art

[0002] Fluorescence in situ hybridization (FISH) is a method for detecting and locating specific DNA sequences on chromosomes. This technology is widely used in gene localization, chromosome aberration detection, chromosome smearing and other fields. In the FISH detection process, the preservation and management of slides are very important links. The traditional slide preservation method has problems such as cumbersome operation and unstable temperature control, which affects the accuracy and repeatability of hybridization. Therefore, it is necessary to place the slides in a constant temperature box to ensure that the temperature is stable and does not affect the accuracy and repeatability of hybridization.

[0003] In the prior art, when storing glass slides, they are usually placed directly inside the constant temperature box, and the glass slides cannot be placed in an orderly manner. Not only are the storage relatively messy and difficult to find, but the internal space of the constant temperature box is wasted. At the same time, it is also very inconvenient when multiple groups of glass slides need to be called.

[0004] Based on this, it is necessary to propose a constant temperature storage device for chromosome FISH detection slides. Summary of the invention

[0005] In view of the shortcomings of the prior art, the present invention provides a constant temperature storage device for chromosome FISH detection slides, which has the advantages of orderly storing slides and rationally utilizing the space inside the constant temperature box. It is also very convenient when multiple groups of slides need to be called, thus solving the problems raised in the background technology.

[0006] The present invention provides the following technical solution: a constant temperature storage device for chromosome FISH detection slides, comprising a constant temperature box, a suitcase, a spacer, a carrying plate and a partition:

[0007] There are several suitcases and all of them are located inside the thermostatic box. Feet are fixedly connected at the four corners of the bottom of the thermostatic box. A double-layer glass cabinet door is provided on the side of the thermostatic box. A top cover is provided on the top of the thermostatic box. The partition is fixedly connected to the inner wall of the suitcase. The partition strips are located on both sides of the partition. There are several supporting plates, and the supporting plates are all located inside the suitcase. An independent box for glass slides is placed on the upper surface of the supporting plate.

[0008] Preferably, a grid groove is formed on the surface of the carrier plate.

[0009] Preferably, both ends of the supporting plate are fixedly connected with edge blocks, the inner surface of the edge block is provided with an edge groove, the inner part of the edge groove is slidably engaged with a movable frame, one end of the movable frame is rotatably connected with a rubber roller, the side of the movable frame is fixedly connected with a spring three, the end of the spring three is fixedly connected to the inner wall of the edge groove, and the rubber roller is in contact with the side of the independent glass slide box.

[0010] Preferably, several of the placement spacers are fixedly connected to the inner wall of the suitcase, the side block is located between two placement spacers, one end of the placement spacer is provided with an installation groove, the inner wall of the installation groove is provided with a built-in groove, the interior of the built-in groove is slidably connected with a card block, and the bottom end of the side block is provided with a card slot, and the card slot matches the model and specification of the card block.

[0011] Preferably, a second spring is fixedly connected to the bottom end of the clamping block, and the bottom end of the second spring is fixedly connected to the bottom of the built-in groove.

[0012] Preferably, a slider is slidably inserted inside the installation groove, one end of the slider is fixedly connected to a guide inclined plate, and the end of the guide inclined plate away from the slider is fixedly connected to an L-shaped plate, and the L-shaped plate passes through the block.

[0013] Preferably, one end of the L-shaped plate is fixedly connected to a spring 1, and the other end of the spring 1 is fixedly connected to the inner wall of the mounting groove.

[0014] Preferably, a spring four is fixedly connected to the side of the partition, an end of the spring four is fixedly connected to a top plate, and the side of the top plate is fitted with the end of the side block.

[0015] Preferably, a label clip and a handle are provided at the top of the suitcase, a partition frame is fixedly connected to the inner wall of the thermostatic box, the partition frame is located between two adjacent suitcases, and a shock-absorbing pad is provided at the inner bottom of the thermostatic box.

[0016] Preferably, both side surfaces of the thermostatic box are provided with a plurality of double-layer glass cabinet doors, and the plurality of double-layer glass cabinet doors correspond one-to-one to the positions of a plurality of suitcases, and the top cover is fixedly connected to the thermostatic box by fasteners.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] 1. This constant temperature storage device for chromosome FISH detection slides is provided with a suitcase, placement spacers and a carrying plate. The independent slide box loaded with slides is placed on the upper surface of the carrying plate. At this time, two rubber rollers are clamped on both sides of the independent slide box, so that the independent slide box is fixed on the upper surface of the carrying plate, which is very convenient when taking out the independent slide box. At the same time, multiple groups of placement spacers are provided on the inner walls of both sides of the suitcase. At this time, the edge blocks at both ends of the carrying plate can be placed on the upper surface of the placement spacers, so that multiple groups of placement spacers can be stacked, which not only saves a lot of space, but also facilitates the search for the independent slide box. Both sides of the suitcase have storage and retrieval functions, which greatly improves the search efficiency when taking out the independent slide box.

[0019] 2. This constant temperature storage device for chromosome FISH detection slides is provided with multiple suitcases, and multiple sets of suitcases can be directly placed inside the constant temperature box. After opening the double-layer glass cabinet door, the independent slide boxes at the corresponding position can be taken out. After opening the top cover, the person can hold the handle to lift the suitcase, which is convenient for calling multiple independent slide boxes at the same time and convenient for carrying multiple independent slide boxes at the same time. During transportation, since the card block is connected to the inside of the card slot, it is effectively prevented that the carrier plate falls off from the inside of the suitcase, and when the carrier plate is taken out When the carrying plate is in the suitcase, only the slider needs to be pushed manually. At this time, the slider drives the guide inclined plate to move, so that the bottom end of the guide inclined plate presses the inner wall of the card block, drives the card block to move downward, and releases the card connection between the card block and the card slot. The elastic force of the fourth spring is applied to the side block to eject the carrier plate, so that the carrier plate and the independent glass slide box can be easily pulled out from the inside of the suitcase. When the carrier plate needs to be stored, the side block is inserted into the top of the partition bar. When the card slot corresponds to the position of the built-in slot, the elastic force of the second spring is applied to the card block, so that the card block is inserted into the inside of the card slot. The operation is simple and quick. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the overall structure of the device of the present invention;

[0021] Figure 2 This is a schematic diagram of the internal structure of the thermostat of the present invention;

[0022] Figure 3 It is a schematic diagram of the structure of the suitcase of the present invention;

[0023] Figure 4 It is a structural schematic diagram of the bearing plate of the present invention;

[0024] Figure 5 This is a schematic diagram of the cross-sectional structure of placing spacers in the present invention.

[0025] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0026] 100, thermostat; 101, foot pad; 102, double-layer glass cabinet door; 103, top cover; 104, fastener; 105, shock-absorbing pad; 106, partition frame;

[0027] 200, suitcase; 201, label holder; 202, handle;

[0028] 300, spacer bar placement; 301, mounting slot; 302, slider; 303, guide inclined plate; 304, L-shaped plate; 305, spring 1; 306, built-in slot;

[0029] 400, card block; 401, spring 2;

[0030] 500, slide independent box;

[0031] 600, bearing plate; 601, side block; 602, side groove; 603, moving frame; 604, rubber roller; 605, spring three; 606, card slot; 607, grid slot.

[0032] 700, partition; 701, spring four; 702, top plate. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific embodiments.

[0035] FISH technology has a wide range of applications in the field of molecular cytogenetics. Its principle is to use fluorescently labeled DNA probes to perform in situ hybridization with DNA in the sample and observe the fluorescent signal under a fluorescence microscope for diagnosis. The accuracy and sensitivity of FISH operation depend on the design of the probe, the preparation of the sample, and the precise control of the in situ hybridization process. Among them, temperature, light, humidity, and pH value of various reagents are important factors affecting FISH operation.

[0036] The main reasons for keeping slides at a constant temperature include: Maintaining hybridization efficiency: Temperature directly affects the hybridization efficiency between the probe and the target DNA. If the temperature fluctuates, it may lead to reduced hybridization efficiency and affect the accuracy of the experimental results. Preventing fluorescence quenching: Light will affect the intensity of fluorescent dyes. Therefore, the probes and the slides after hybridization need to be kept away from light to prevent fluorescence quenching. Maintaining stable chemical reaction conditions: The pH value of various reagents needs to be precisely controlled to ensure the stability and repeatability of the FISH reaction.

[0037] In summary, constant temperature storage can effectively maintain the hybridization efficiency between the probe and sample DNA during the FISH experiment, prevent fluorescence signal quenching, and ensure the stability of chemical reaction conditions, thereby ensuring the accuracy and reliability of FISH experimental results.

[0038] As an advanced molecular cytogenetic technology, FISH technology has a wide range of applications in many fields, including genetic diseases: Detection of chromosome structural abnormalities: Through the pairing detection of specific sequences, it helps doctors accurately detect genetic lesions, including chromosome deletions, translocations, duplications and other problems. Gene mutation detection: By combining fluorescently labeled probes with target sequences, specific gene mutations can be detected, which is crucial for the diagnosis of genetic diseases. Chromosome rearrangement detection: FISH technology can detect chromosome rearrangements, which is of great significance for understanding the occurrence mechanism and inheritance pattern of diseases. Diagnosis of polygenic diseases: FISH technology can detect multiple genes at the same time, providing important information for the diagnosis of polygenic diseases, gene localization and mutation mechanism research: FISH technology can help determine the exact location of genes on chromosomes, and study the mechanism of gene mutation. Oncology, cancer diagnosis and grading: By detecting chromosomal abnormalities or gene mutations in cancer cells, it helps doctors confirm the type, grade and prognosis of tumors. Cancer prognosis assessment: FISH technology can assess the prognosis of cancer patients and provide a basis for treatment decisions. Cancer treatment monitoring: Monitor the changes in chromosomes and genes during cancer treatment and evaluate the treatment effect. Cancer-related gene research: FISH technology helps to study the function and expression of cancer-related genes and deeply understand the occurrence mechanism of cancer. Research on the mechanism of tumor occurrence: By detecting genetic changes in tumor cells, the occurrence and development mechanism of tumors is studied. Genetic counseling, family genetic disease risk assessment: FISH technology can be used to assess the risk of genetic diseases in the family and provide a scientific basis for genetic counseling. Individual genetic risk prediction: By detecting the chromosome and gene status of an individual, the risk of genetic diseases can be predicted. Pathological diagnosis, chromosome abnormality detection: FISH technology is used to detect chromosome abnormalities, such as Down syndrome, in pathological diagnosis. Gene amplification detection: Detecting gene amplification provides important information for disease diagnosis. Gene fusion detection: Detecting gene fusion events through FISH technology is of great significance for the diagnosis of certain diseases. Targeted therapy, guiding the application of targeted drugs: FISH technology can guide the selection and application of targeted drugs to achieve personalized treatment. Detection of micro-residual lesions: FISH technology is very sensitive to the detection of micro-residual lesions, which helps to evaluate the treatment effect and recurrence risk. Hematological tumors, hematological tumor diagnosis: Detecting specific molecular markers in hematological tumors through FISH technology provides a basis for diagnosis. Risk stratification assessment: FISH technology can help risk stratify patients with hematological malignancies and guide the formulation of treatment plans.

[0039] FISH (fluorescence in situ hybridization) technology is an important molecular cytogenetic method, which is widely used in the fields of chromosome abnormality detection, gene localization and gene amplification analysis. In FISH experiments, probe design and sample preparation are key steps, and sample storage conditions are also crucial to the stability and accuracy of experimental results.

[0040] Nowadays, when storing FISH test slides, they are directly placed in a constant temperature box, and the storage layout of the FISH test slides is not optimized, resulting in a huge waste of space in the constant temperature box. At the same time, when taking out, it is very inconvenient to find the FISH test slides because they are stacked together.

[0041] See also Figure 1-5 A constant temperature storage device for chromosome FISH detection slides includes a constant temperature box 100, a suitcase 200, a spacer 300, a carrier plate 600 and a partition 700:

[0042] There are several suitcases 200 and all of them are located inside the thermostatic box 100. Feet 101 are fixedly connected at the four corners of the bottom of the thermostatic box 100. A double-layer glass cabinet door 102 is provided on the side of the thermostatic box 100. A top cover 103 is provided on the top of the thermostatic box 100. The partition 700 is fixedly connected to the inner wall of the suitcase 200, and the partition strips 300 are placed on both sides of the partition 700. There are several supporting plates 600, and the several supporting plates 600 are all located inside the suitcase 200. An independent glass slide box 500 is placed on the upper surface of the supporting plate 600.

[0043] For further preference, see Figure 1 , Figure 4 The surface of the carrier plate 600 is provided with a grid groove 607. The weight of the device can be reduced, and the device is lightweight and easy to carry.

[0044] For further preference, see Figure 1 , Figure 4 , both ends of the carrier plate 600 are fixedly connected with edge blocks 601, the inner surface of the edge blocks 601 is provided with edge grooves 602, the inner surface of the edge grooves 602 is slidably connected with a moving frame 603, one end of the moving frame 603 is rotatably connected with a rubber roller 604, the side of the moving frame 603 is fixedly connected with a spring three 605, the end of the spring three 605 is fixedly connected with the inner wall of the edge groove 602, and the rubber roller 604 is in contact with the side of the independent glass slide box 500. The independent glass slide box 500 loaded with glass slides is placed on the upper surface of the carrier plate 600, at which time the two rubber rollers 604 are clamped on both sides of the independent glass slide box 500, and the elastic force of the spring three 605 is applied to the rubber roller 604, thereby fixing the independent glass slide box 500 on the upper surface of the carrier plate 600.

[0045] For further preference, see Figure 4 , Figure 5, a plurality of placement bars 300 are fixedly connected to the inner wall of the suitcase 200, the side block 601 is located between two placement bars 300, one end of the placement bar 300 is provided with a mounting groove 301, the inner wall of the mounting groove 301 is provided with a built-in groove 306, the inner wall of the built-in groove 306 is provided with a block 400 that is slidably engaged, and the bottom end of the side block 601 is provided with a slot 606, the slot 606 is consistent with the model and specification of the block 400. When the block 400 is engaged in the slot 606, the position of the side block 601 can be fixed.

[0046] For further preference, see Figure 4 , Figure 5 The bottom end of the card block 400 is fixedly connected with a second spring 401, and the bottom end of the second spring 401 is fixedly connected to the bottom of the built-in slot 306. The elastic force of the second spring 401 is applied to the card block 400. In the absence of external force, the second spring 401 will lift the card block 400, so that the card block 400 is clamped inside the card slot 606.

[0047] For further preference, see Figure 4 , Figure 5 A slider 302 is slidably inserted inside the mounting groove 301, one end of the slider 302 is fixedly connected to a guide inclined plate 303, an end of the guide inclined plate 303 away from the slider 302 is fixedly connected to an L-shaped plate 304, the L-shaped plate 304 passes through the block 400, one end of the L-shaped plate 304 is fixedly connected to a spring 305, and the other end of the spring 305 is fixedly connected to the inner wall of the mounting groove 301. The slider 302 is pushed manually, and the slider 302 drives the guide inclined plate 303 to move, so that the bottom end of the guide inclined plate 303 squeezes the inner wall of the block 400, drives the block 400 to move downward, and releases the clamping relationship between the block 400 and the clamping slot 606. When the carrier plate 600 needs to be stored, the side block 601 is inserted into the top of the partition bar 300. When the position of the clamping slot 606 corresponds to the position of the built-in slot 306, the elastic force of the spring 2 401 is applied to the block 400, so that the block 400 is clamped into the inside of the clamping slot 606.

[0048] For further preference, see Figure 3 , Figure 4 The side of the partition 700 is fixedly connected with a spring 701, the end of the spring 701 is fixedly connected with a top plate 702, and the side of the top plate 702 is in contact with the end of the edge block 601. The elastic force of the spring 701 is applied to the edge block 601 to eject the carrier plate 600, so that the carrier plate 600 and the independent slide box 500 can be easily pulled out from the interior of the suitcase 200.

[0049] For further preference, see Figure 2 , Figure 3The top of the suitcase 200 is provided with a label clip 201 and a handle 202, the inner wall of the thermostat 100 is fixedly connected with a partition frame 106, the partition frame 106 is located between two adjacent suitcases 200, and the inner bottom of the thermostat 100 is provided with a shock-absorbing pad 105. The setting of the handle 202 facilitates lifting the suitcase 200, the setting of the label clip 201 can be used to place notes, and the setting of the shock-absorbing pad 105 can provide protection for the suitcase 200 when the suitcase 200 is placed in the thermostat 100.

[0050] For further preference, see Figure 1 , Figure 2 The surfaces of both sides of the thermostat 100 are provided with a plurality of double-layer glass doors 102, and the positions of the plurality of double-layer glass doors 102 correspond to the plurality of suitcases 200 one by one, and the top cover 103 is fixedly connected to the thermostat 100 through a fastener 104. When the suitcase 200 is inside the thermostat 100, it is still convenient to take and put the independent slide box 500.

[0051] Working principle: Place the slide box 500 loaded with slides on the upper surface of the carrier plate 600. At this time, two rubber rollers 604 are clamped on both sides of the slide box 500, so that the slide box 500 is fixed on the upper surface of the carrier plate 600. It is very convenient to take the slide box 500. At the same time, multiple groups of spacers 300 are arranged on the inner walls of both sides of the suitcase 200. At this time, the edge blocks 601 at both ends of the carrier plate 600 can be placed on the upper surface of the spacers 300. , so that multiple groups of spacers 300 can be stacked, which not only saves a lot of space, but also facilitates the search of the independent glass slide boxes 500. Multiple groups of suitcases 200 can be directly placed inside the constant temperature box 100. After opening the double-layer glass cabinet door 102, the independent glass slide boxes 500 at the corresponding position can be taken. After opening the top cover 103, the person can hold the handle 202 to lift the suitcase 200, which is convenient for calling multiple independent glass slide boxes 500 at the same time, and is convenient for simultaneous The plurality of independent slide boxes 500 are transported. During the transport, since the card block 400 is connected to the inside of the card slot 606, the carrier plate 600 is effectively prevented from falling off from the inside of the suitcase 200. When the carrier plate 600 is taken out, it is only necessary to manually push the slider 302. At this time, the slider 302 drives the guide inclined plate 303 to move, so that the bottom end of the guide inclined plate 303 presses the inner wall of the card block 400, drives the card block 400 to move downward, and releases the card block 400 from the card slot 606. 6, the elastic force of spring four 701 is applied to the edge block 601 to pop out the carrier plate 600, which is convenient for pulling out the carrier plate 600 together with the independent glass slide box 500 from the interior of the suitcase 200. When the carrier plate 600 needs to be stored, the edge block 601 is snapped into the top of the partition bar 300. When the position of the slot 606 corresponds to the position of the built-in slot 306, the elastic force of spring two 401 is applied to the block 400, so that the block 400 is snapped into the interior of the slot 606.

[0052] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0053] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A constant temperature storage device for chromosome FISH detection slides, characterized in that: It includes a constant temperature box (100), a suitcase (200), a spacer (300), a carrying plate (600) and a partition (700): The suitcase (200) is provided with a plurality of feet (101) and all of them are located inside the thermostatic box (100). The four corners of the bottom of the thermostatic box (100) are fixedly connected with feet (101). The side of the thermostatic box (100) is provided with a double-layer glass cabinet door (102). The top of the thermostatic box (100) is provided with a top cover (103). The partition (700) is fixedly connected to the inner wall of the suitcase (200). The placement strips (300) are located on both sides of the partition (700). The number of the supporting plates (600) is a plurality, and the plurality of supporting plates (600) are all located inside the suitcase (200). An independent glass slide box (500) is placed on the upper surface of the supporting plate (600).

2. A constant temperature storage device for chromosome FISH detection slides according to claim 1, characterized in that: A grid groove (607) is formed on the surface of the carrier plate (600).

3. A constant temperature storage device for chromosome FISH detection slides according to claim 1, characterized in that: Both ends of the carrying plate (600) are fixedly connected with edge blocks (601), the inner surface of the edge block (601) is provided with an edge groove (602), the inner part of the edge groove (602) is slidably engaged with a movable frame (603), one end of the movable frame (603) is rotatably connected with a rubber roller (604), the side of the movable frame (603) is fixedly connected with a spring three (605), the end of the spring three (605) is fixedly connected with the inner wall of the edge groove (602), and the rubber roller (604) is in contact with the side of the independent glass slide box (500).

4. A constant temperature storage device for chromosome FISH detection slides according to claim 3, characterized in that: A plurality of the placement partitions (300) are fixedly connected to the inner wall of the suitcase (200), the side block (601) is located between two placement partitions (300), one end of the placement partition (300) is provided with a mounting groove (301), the inner wall of the mounting groove (301) is provided with a built-in groove (306), the interior of the built-in groove (306) is slidably engaged with a card block (400), the bottom end of the side block (601) is provided with a card slot (606), and the model and specification of the card slot (606) are consistent with those of the card block (400).

5. A constant temperature storage device for chromosome FISH detection slides according to claim 4, characterized in that: The bottom end of the clamping block (400) is fixedly connected to a second spring (401), and the bottom end of the second spring (401) is fixedly connected to the bottom of the built-in groove (306).

6. A constant temperature storage device for chromosome FISH detection slides according to claim 4, characterized in that: A slider (302) is slidably inserted inside the installation groove (301), one end of the slider (302) is fixedly connected to a guide inclined plate (303), and one end of the guide inclined plate (303) away from the slider (302) is fixedly connected to an L-shaped plate (304), and the L-shaped plate (304) passes through the clamping block (400).

7. A constant temperature storage device for chromosome FISH detection slides according to claim 6, characterized in that: One end of the L-shaped plate (304) is fixedly connected to a spring 1 (305), and the other end of the spring 1 (305) is fixedly connected to the inner wall of the mounting groove (301).

8. A constant temperature storage device for chromosome FISH detection slides according to claim 3, characterized in that: The side of the partition (700) is fixedly connected to a spring four (701), the end of the spring four (701) is fixedly connected to a top plate (702), and the side of the top plate (702) is in contact with the end of the edge block (601).

9. A constant temperature storage device for chromosome FISH detection slides according to claim 1, characterized in that: The top of the suitcase (200) is provided with a label clip (201) and a handle (202); the inner wall of the thermostatic box (100) is fixedly connected with a partition frame (106); the partition frame (106) is located between two adjacent suitcases (200); and the inner bottom of the thermostatic box (100) is provided with a shock-absorbing pad (105).

10. A constant temperature storage device for chromosome FISH detection slides according to claim 1, characterized in that: A plurality of double-layer glass cabinet doors (102) are provided on both side surfaces of the thermostatic box (100), and the positions of the plurality of double-layer glass cabinet doors (102) and the plurality of suitcases (200) correspond one to one, and the top cover (103) is fixedly connected to the thermostatic box (100) via fasteners (104).

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