Smearing mask with anti-oxidation effect and preparation method thereof

Abstract

The invention discloses a smearing mask with an anti-oxidation effect. The smearing mask is prepared from the following components in percentage by weight: 2 to 10 percent of glyceryl monostearate, 1 to 5 percent of glyceryl distearate, 1 to 10 percent of butanediol, 0.1 to 1 percent of xanthan gum, 10 to 30 percent of pomegranate fruit extract, 2 to 5 percent of fibroin, 0.1 to 1 percent of hexanediol and the balance of water. The smearing mask disclosed by the invention is natural, mild and non-irritant, and has an anti-oxidation effect. The pomegranate fruit extract and the silk protein are jointly added, so that the DPPH free radical scavenging capacity of a sample is remarkably improved. The pomegranate fruit extract and the silk protein are added together, so that the hydroxyl radical scavenging capacity of a sample is remarkably improved.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to a smearable facial mask with antioxidant effect and a preparation method thereof, and in particular to a smearable facial mask comprising pomegranate fruit extract and silk protein and having antioxidant effect and a preparation method thereof. Technical Background

[0002] The skin is the first barrier of the human body and directly reflects the aging of the body. On the one hand, the body's ability to remove free radicals decreases with aging. On the other hand, external stimuli such as ultraviolet rays and haze cause cell oxidation to produce free radicals. Excessive free radicals in the body cause cell oxidation damage, increase tyrosinase activity, accelerate the pigment synthesis process, cause skin aging, and cause wrinkles, spots and other problems. Therefore, removing excess free radicals is currently a hot research direction for anti-aging cosmetics.

[0003] Plants are natural sources of antioxidants. For example, pomegranate fruit extract not only has significant antioxidant effects, but is also natural, mild, and non-irritating, making it suitable for addition to skin care products.

[0004] Silk protein, also known as fibroin, is a natural high-molecular fiber protein extracted from silk. Silk protein accounts for about 70%-80% of silk, contains 18 kinds of amino acids, and is divided into inner silk fibroin and outer sericin. Among them, silk fibroin contains serine, aspartic acid, lysine and glutamic acid, etc. It is a complex composed of heavy chain, light chain and glycoprotein, and is a natural block copolymer. Silk protein has good biocompatibility and biodegradability. It is not only used in the textile industry to make silk and other products, but also has a wide range of applications in cosmetics and medical fields.

[0005] The antioxidant system is a complex system involving the synergistic effects of multiple additives. Developing a product that has the effect of scavenging free radicals and maintaining the redox balance in the body is a technical problem that people in this field need to solve urgently. Summary of the invention

[0006] The invention aims to provide a smearable facial mask with anti-oxidation effect.

[0007] Another object of the present invention is to provide a method for preparing the above-mentioned facial mask with antioxidant effect.

[0008] The purpose of the present invention is achieved through the following scheme: a smearable facial mask with antioxidant effect, which contains an oil phase, an aqueous phase and an antioxidant composition; the oil phase is composed of 2-10% monostearate glyceryl and 1-5% distearate glyceryl; the aqueous phase is composed of 1-10% butylene glycol, 0.1-1% xanthan gum and the remainder is deionized water; the antioxidant composition is 10-30% pomegranate fruit extract and 2-5% silk protein.

[0009] Furthermore, a preservative is added to the mask, and the amount of the preservative in the mask is: 0.1-1%; The preservative is hexylene glycol.

[0010] The present invention also provides a method for preparing a smearable facial mask with antioxidant efficacy, comprising the following steps: Weigh the oil phase in proportion, stir and mix thoroughly at 60-80°C, let it stand to defoam, add the water phase in proportion, continue heating and stirring evenly, and after the temperature drops to room temperature, add the preservative in proportion and stir evenly. Finally, add the antioxidant composition and stir evenly to obtain a smearable facial mask with antioxidant effect.

[0011] The smearable facial mask disclosed by the present invention is natural, mild, non-irritating, and has an antioxidant effect. The pomegranate fruit extract and silk protein are added together to significantly improve the DPPH free radical scavenging ability of the sample. The pomegranate fruit extract and silk protein are added together to significantly improve the hydroxyl free radical scavenging ability of the sample. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 DPPH free radical scavenging ability of each embodiment and comparative example; Figure 2 It is the hydroxyl radical scavenging ability of each embodiment and comparative example. DETAILED DESCRIPTION

[0013] The present invention will be further described below by means of the following examples and accompanying drawings.

[0014] Pomegranate fruit extract is self-extracted, and the specific extraction method is as follows: take fresh pomegranates and separate the pomegranate peel. After washing and drying, crush the pomegranate peel into 60 meshes, add 20% ethanol solution in an amount 20 times its mass, and perform ultrasonic extraction at a temperature of 55-75°C, an ultrasonic power of 60W, and an extraction time of 2h, and then filter, concentrate, and freeze-dry to obtain the pomegranate peel extract.

[0015] Example 1 A smearable facial mask with antioxidant effect, comprising an oil phase, an aqueous phase and an antioxidant composition, wherein the components of the oil phase are 5% glyceryl monostearate and 2.5% glyceryl distearate; the components of the aqueous phase are 2% butylene glycol, 0.5% xanthan gum and the balance is deionized water; the antioxidant composition is 10% pomegranate fruit extract and 2.5% silk protein; and the preservative hexylene glycol is 0.5%, and is prepared according to the following steps: Weigh the oil phase in proportion, stir and mix thoroughly at 60-80℃, and let stand to defoam; Add water phase according to the formula amount, continue heating and stirring evenly, and after the temperature drops to room temperature, add preservatives and stir evenly; Finally, the antioxidant composition is added and stirred evenly to obtain a smearable facial mask with antioxidant effect.

[0016] See the effect Figure 1 and Figure 2 .

[0017] Example 2 A facial mask with antioxidant effect, comprising an oil phase, an aqueous phase and an antioxidant composition, wherein the components of the oil phase are 5% glyceryl monostearate and 2.5% glyceryl distearate; the components of the aqueous phase are 2% butylene glycol, 0.5% xanthan gum and the balance is deionized water; the antioxidant composition is 20% pomegranate fruit extract and 2.5% silk protein; the preservative hexylene glycol is 0.5%, and the preparation method is the same as that in Example 1.

[0018] Example 3 A facial mask with antioxidant effect, comprising an oil phase, an aqueous phase and an antioxidant composition, wherein the components of the oil phase are 5% glyceryl monostearate and 2.5% glyceryl distearate; the components of the aqueous phase are 2% butylene glycol, 0.5% xanthan gum and the balance is deionized water; the antioxidant composition is 30% pomegranate fruit extract and 2.5% silk protein; the preservative hexylene glycol is 0.5%, and the preparation method is the same as that in Example 1.

[0019] Comparative Example 1 A facial mask with antioxidant effect, which differs from Examples 1 to 3 in that pomegranate fruit extract is not added, and contains an oil phase, an aqueous phase and an antioxidant composition, wherein the components of the oil phase are 5% monostearate glyceryl and 2.5% distearate glyceryl; the components of the aqueous phase are 2% butylene glycol, 0.5% xanthan gum and the balance is deionized water; 2.5% silk protein; and 0.5% hexylene glycol as a preservative. The preparation method is the same as that of Example 1.

[0020] Comparative Example 2 A facial mask with antioxidant effect, which differs from Example 2 in that no silk protein is added, contains an oil phase, an aqueous phase and an antioxidant composition, wherein the components of the oil phase are 5% monostearate glyceryl and 2.5% distearate glyceryl; the components of the aqueous phase are 2% butylene glycol, 0.5% xanthan gum and the balance is deionized water; 20% pomegranate fruit extract; and 0.5% hexylene glycol as a preservative. The preparation method is the same as that of Example 1.

[0021] Performance Testing Methods Experiment: DPPH free radical scavenging ability test Principle: DPPH is a stable nitrogen free radical. Its methanol or ethanol solution is dark purple. When a free radical scavenger is added to the DPPH free radical solution, the dark purple DPPH free radical The radical is reduced to a yellow DPPH-H non-radical form, and the degree of fading is quantitatively related to the number of electrons accepted, so it can be quantitatively analyzed by changes in absorbance.

[0022] Experimental steps: (1) Dissolve 0.001 g DPPH in 25 mL ethanol to prepare a 0.1 mM DPPH solution and store in a dark place.

[0023] (2) Set up a sample group, a control group, and a blank group, with three replicates for each group, and incubate at room temperature in the dark for 30 minutes.

[0024] Sample group: sample solution 100uL + DPPH alcohol solution 100uL; Blank group: sample solution 100uL + anhydrous ethanol 100uL; Control group: DPPH alcohol solution 100uL + water 100uL.

[0025] (3) Use an ELISA reader to measure the absorbance of each group at 517 nm.

[0026] DPPH clearance rate = (1-(OD sample -OD blank ) / OD control )*100%, where OD sample is the absorbance value of the sample group, OD blank is the absorbance value of the blank group, OD control is the absorbance value of the control group.

[0027] from Figure 1 The experimental results show that both the embodiment and the comparative example show antioxidant properties. The DPPH free radical scavenging ability of the embodiment is higher than that of the comparative example, indicating that the co-addition of pomegranate fruit extract and silk protein significantly improves the DPPH free radical scavenging ability of the sample. In the embodiment, the more pomegranate fruit extract, the higher the DPPH free radical scavenging ability of the sample.

[0028] Experiment: Hydroxyl free radical scavenging ability test Principle: H2O2 reacts with ferrous ions to generate hydroxyl radicals, which have high reactivity. When salicylic acid is added to the reaction system, it can quickly capture hydroxyl radicals to produce purple compounds, which have a large absorption peak at 510nm, and its absorbance is proportional to the amount of hydroxyl radicals. If a hydroxyl radical scavenger is added to the reaction system, the oxidized salicylic acid will decrease, the color of the system will become lighter, and the absorbance will decrease. The decrease in the absorbance level indicates an increase in antioxidant activity, thereby evaluating the antioxidant capacity of the test sample.

[0029] Experimental steps: (1) Set up a sample group, a sample background group, and a blank group, with three replicates for each group, and incubate at 37°C for 30 min.

[0030] Sample group: 1mmol / l ferrous sulfate solution 5ml + 3mmol / l H2O2 solution 5ml + sample 1ml; Sample background group: 1mmol / l ferrous sulfate solution + 5ml aqueous solution + 1ml sample; Blank group: 5 ml of 1 mmol / l ferrous sulfate solution + 5 ml of 3 mmol / l H2O2 solution + 1 ml of aqueous solution.

[0031] (2) Use an ELISA reader to measure the absorbance of each group at 510 nm.

[0032] Hydroxyl radical scavenging rate = (OD0-(OD1-OD2) / OD0)*100%, wherein OD0 is the absorbance value of the blank group, OD1 is the absorbance value of the sample group, and OD2 is the absorbance value of the sample background group.

[0033] from Figure 2 The experimental results show that both the embodiment and the comparative example show hydroxyl radical scavenging ability. The hydroxyl radical scavenging ability of the embodiment is higher than that of the comparative example, indicating that the co-addition of pomegranate fruit extract and silk protein significantly improves the hydroxyl radical scavenging ability of the sample. In the embodiment, the more pomegranate fruit extract, the higher the hydroxyl radical scavenging ability of the sample.

Claims

1. A facial mask with antioxidant effect, characterized in that: The facial mask contains an oil phase, an aqueous phase and an antioxidant composition, wherein the components of the oil phase are 2-10% of glyceryl monostearate and 1-5% of glyceryl distearate; the components of the aqueous phase are 1-10% of butylene glycol, 0.1-1% of xanthan gum and the balance is deionized water; and the antioxidant composition is 10-30% of pomegranate fruit extract and 2-5% of silk protein.

2. The facial mask with antioxidant effect according to claim 1, characterized in that: A preservative is added to the facial mask, and the amount of the preservative in the facial mask is 0.1-1%.

3. The facial mask with antioxidant effect according to claim 3, characterized in that: The preservative is hexylene glycol.

4. The facial mask with antioxidant effect according to claim 1 or 2, characterized in that: The components and dosage thereof are: 2-10% of monostearic acid glyceryl, 1-5% of distearic acid glyceryl, 1-10% of butylene glycol, 0.1-1% of xanthan gum, 10-30% of pomegranate fruit extract, 2-5% of silk protein, 0.1-1% of hexylene glycol, and the balance is water.

5. A method for preparing a facial mask with antioxidant efficacy according to any one of claims 1 to 4, characterized in that The following steps are involved: Weigh the oil phase in proportion, stir and mix thoroughly under heating conditions of 60-80°C, let stand to defoam, add the water phase in proportion, continue heating and stirring evenly, after the temperature drops to room temperature, add the preservative in proportion and stir evenly; finally, add the antioxidant composition, stir evenly to obtain a smearable facial mask with antioxidant effect.

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