ECMO rapid pre-charging system suitable for out-of-hospital emergency rescue and use method of ECMO rapid pre-charging system

Abstract

The invention relates to an ECMO rapid pre-filling system suitable for out-of-hospital emergency rescue and a using method.The rapid pre-filling system sequentially comprises a pre-filling bag, a rolling pump, a centrifugal pump and an oxygenator in the pre-filling liquid flowing direction, the pre-filling bag is provided with a liquid outlet and a liquid return opening, the liquid outlet of the pre-filling bag is communicated with the rolling pump through a first pipeline, and the rolling pump is communicated with the centrifugal pump through a second pipeline; the rolling pump is communicated with a liquid inlet of the centrifugal pump through a second pipeline, a liquid outlet of the centrifugal pump is communicated with a liquid inlet of the oxygenator through a third pipeline, and a liquid outlet of the oxygenator is communicated with a liquid return opening of the pre-filling bag through a fourth pipeline. The rolling pump is additionally arranged in the pre-filling liquid loop to serve as a power source, so that the pre-filling liquid can be quickly injected into the pipeline loop to be pre-filled, the efficiency is high, and the time is short.

Description

Technical Field

[0001] The present invention relates to the field of medical device technology, and in particular to an ECMO rapid pre-filling system suitable for out-of-hospital emergency rescue and a use method thereof. Background Art

[0002] Extracorporeal membrane oxygenation (ECMO) is mainly used to provide continuous extracorporeal respiration and circulation to patients with severe cardiopulmonary failure in order to maintain the patient's life. It is commonly used for emergency rescue. It can quickly and promptly start life support at the scene of acute cardiovascular disease or acute respiratory disease, which is conducive to avoiding multiple organ failure caused by the deterioration of the disease and greatly improving the patient's survival rate. The ECMO system includes pipes, oxygenators, blood pumps, monitoring systems and other parts. It draws human venous blood out of the body, drives the blood to circulate through the blood pump, and oxygenates the blood through the oxygenator before returning it to the human body, thereby maintaining the patient's vital signs.

[0003] Before connecting the patient to the ECMO system, the ECMO pipeline needs to be pre-filled with saline and the gas needs to be exhausted to prevent the gas from entering the human body and causing gas embolism. However, in the prior art, the ECMO bag circuit is relatively long and involves components with complex internal structures such as centrifugal pumps and oxygenators. Relying on traditional gravity exhaust requires repeated adjustments by the operator, which is inefficient and time-consuming. At the same time, because this method does not have additional power assistance for the pre-filled liquid flow, it only relies on the high hanging height of the pre-filled liquid bag to allow the pre-filled liquid to flow into the consumables under the action of gravity, the filling speed is low and the operating space requirements are high; however, due to the urgency of the disease, such as brain hypoxia for 4-6 minutes, which usually leads to death, and ECMO consumables all need to be pre-filled and exhausted to support operation,

[0004] Therefore, if the priming time can be compressed as much as possible, it is possible to effectively improve the patient's survival rate after treatment.

[0005] Moreover, because the priming bag is located in front of the centrifugal pump in the pipeline structure, when the extracorporeal cardiopulmonary support system is running after priming, the negative pressure at the front end of the centrifugal pump increases. If the patient's cardiac preload is low, it is difficult to maintain an effective circulation flow, and other venous access needs to be established to infuse the patient with fluids. The additional operation and the circulation loop increase the risk of air intake, causing the cardiopulmonary support system to collapse. It is especially difficult to operate in specific environments and small, dim spaces. Summary of the invention

[0006] Based on this, it is necessary to provide an ECMO rapid priming system and method of use suitable for out-of-hospital emergency rescue in response to the above-mentioned technical problems existing in the prior art. By adding a roller pump as a power source in the priming liquid circuit, the priming liquid can be quickly injected into the pipeline circuit to be priming, with high efficiency and short time.

[0007] In order to solve the above technical problems, the technical solution adopted by the present invention is:

[0008] An ECMO rapid priming system suitable for out-of-hospital emergency rescue comprises a priming bag, a roller pump, a centrifugal pump and an oxygenator in order according to the flow direction of the priming liquid. The priming bag is provided with a liquid outlet and a liquid return port. The liquid outlet of the priming bag is connected with the roller pump through a first pipeline, the roller pump is connected with the liquid inlet of the centrifugal pump through a second pipeline, the liquid outlet of the centrifugal pump is connected with the liquid inlet of the oxygenator through a third pipeline, and the liquid outlet of the oxygenator is connected with the liquid return port of the priming bag through a fourth pipeline.

[0009] The present invention adds a roller pump as a power source in the pre-filled liquid circuit, which can quickly inject the pre-filled liquid into the pipeline circuit to be pre-filled, with high efficiency and short time.

[0010] In a feasible implementation, the second pipeline is connected to the fourth pipeline through a fifth pipeline, and a first pipe clamp is provided on the fifth pipeline for connecting or cutting off the flow of liquid in the fifth pipeline. The present invention can switch between the pre-filling pipeline and the normal working pipeline.

[0011] In a feasible implementation, a second pipe clamp is provided on the second pipeline for connecting or cutting off the flow of liquid in the second pipeline, and the second pipe clamp is located between the roller pump and the connection point between the second pipeline and the fifth pipeline. A third pipe clamp is provided on the fourth pipeline for connecting or cutting off the flow of liquid in the fourth pipeline, and the third pipe clamp is located between the pre-filled bag and the connection point between the fourth pipeline and the fifth pipeline. If the centrifugal pump of the present invention fails during operation, it can also be replaced by the roller pump in an emergency to ensure the operation of the system and maintain the vital signs of the patient.

[0012] In a feasible implementation, the fourth pipeline is connected to the first pipeline through a sixth pipeline, and a fourth pipe clamp is provided on the sixth pipeline to connect or cut off the flow of liquid in the sixth pipeline;

[0013] Preferably, a liquid outlet of the pre-filled bag is connected to a liquid outlet pipe, which is detachably connected to the first pipeline, a liquid return pipe is connected to the liquid return port of the pre-filled bag, which is detachably connected to the fourth pipeline, and the sixth pipeline is located between the connection point between the liquid outlet pipe and the first pipeline and the connection point between the liquid return pipe and the fourth pipeline;

[0014] Preferably, the roller pump is arranged on the centrifugal pump. Such arrangement of the present invention can integrate the system, facilitate the miniaturization of the equipment, and facilitate portability.

[0015] In a feasible implementation, the rapid pre-filling system has a first working state, the first tube clamp cuts off the flow of liquid in the fifth pipeline, the fourth tube clamp cuts off the flow of liquid in the sixth pipeline, the second tube clamp connects the flow of liquid in the second pipeline, and the third tube clamp connects the flow of liquid in the fourth pipeline. The roller pump serves as the power source of the entire system, so that the liquid in the pre-filling bag pre-fills and exhausts the entire system.

[0016] In a feasible implementation, the rapid pre-filling system has a second working state, the first tube clamp connects the flow of liquid in the fifth pipeline, the fourth tube clamp connects the flow of liquid in the sixth pipeline, the second tube clamp cuts off the flow of liquid in the second pipeline, and the third tube clamp cuts off the flow of liquid in the fourth pipeline. The fourth pipeline is connected to the human veins and arteries, and the centrifugal pump serves as the power source of the entire system.

[0017] In a feasible implementation, the rapid prefilling system has a third working state, the first tube clamp cuts off the flow of liquid in the fifth pipeline, the second tube clamp connects the flow of liquid in the second pipeline, the third tube clamp connects the flow of liquid in the fourth pipeline, and the fourth tube clamp connects the flow of liquid in the sixth pipeline. The prefilling bag, the liquid outlet pipeline, and the liquid return pipeline are removed, and the fourth pipeline is connected to the human veins and arteries, and the roller pump serves as the power source of the entire system.

[0018] In a feasible implementation, the rapid pre-filling system has a fourth working state, the third pipe clamp cuts off the flow of liquid in the fourth pipeline, the first pipe clamp connects the flow of liquid in the fifth pipeline, the second pipe clamp connects the flow of liquid in the second pipeline, the fourth pipe clamp connects or cuts off the flow of liquid in the sixth pipeline, the fourth pipeline is connected to the human vein and artery, the centrifugal pump serves as the power source of the entire system, and the roller pump replenishes the liquid in the pre-filled bag into the human body. When the patient needs fluid replenishment, the present invention can replenish the liquid in the pre-filled bag into the human body by rotating the roller pump, and can accurately control the amount and speed of fluid replenishment.

[0019] In order to solve the above technical problems, another technical solution adopted by the present invention is:

[0020] A method for using the ECMO rapid priming system as described above comprises the following steps:

[0021] Pre-fill and exhaust the entire system: the first pipe clamp cuts off the flow of liquid in the fifth pipe, the fourth pipe clamp cuts off the flow of liquid in the sixth pipe, the second pipe clamp connects the flow of liquid in the second pipe, and the third pipe clamp connects the flow of liquid in the fourth pipe. The roller pump serves as the power source of the entire system, and the liquid in the pre-fill bag pre-fills and exhausts the entire system.

[0022] In a feasible implementation, the following steps are also included:

[0023] After the exhaust is completed, the fourth pipeline is disconnected and connected to the veins and arteries of the human body respectively, the first pipe clamp is connected to the flow of the liquid in the fifth pipeline, the fourth pipe clamp is connected to the flow of the liquid in the sixth pipeline, the second pipe clamp is cut off the flow of the liquid in the second pipeline, and the third pipe clamp is cut off the flow of the liquid in the fourth pipeline. The centrifugal pump serves as the power source of the entire system;

[0024] Preferably, when the centrifugal pump fails, the first pipe clamp cuts off the flow of the liquid in the fifth pipeline, the second pipe clamp connects the flow of the liquid in the second pipeline, the third pipe clamp connects the flow of the liquid in the fourth pipeline, the fourth pipe clamp connects the flow of the liquid in the sixth pipeline, the pre-filled bag, the liquid outlet pipeline, and the liquid return pipeline are removed, and the roller pump serves as the power source of the entire system;

[0025] Preferably, when the human body needs fluid replenishment at the same time, the third tube clamp cuts off the flow of liquid in the fourth pipeline, the first tube clamp connects the flow of liquid in the fifth pipeline, the second tube clamp connects the flow of liquid in the second pipeline, and the fourth tube clamp connects or cuts off the flow of liquid in the sixth pipeline. The centrifugal pump serves as the power source of the entire system, and the roller pump replenishes the liquid in the pre-filled bag into the human body.

[0026] Due to the adoption of the above technical solution, the present invention has the following advantages compared with the prior art:

[0027] 1. The present invention adds a roller pump as a power source in the pre-filled liquid circuit, which can quickly inject the pre-filled liquid into the pipeline circuit to be pre-filled, with high efficiency and short time;

[0028] 2. The present invention uses a roller pump as a power source for pre-charging instead of a centrifugal pump because the centrifugal pump cannot be used as a power source when the air is not completely discharged, while the roller pump can generate kinetic energy without being affected by the air and can be directly pre-charged, further simplifying the operation and increasing the pre-charging speed;

[0029] 3. The present invention does not require the pre-filled liquid bag to be hung high for operation. Therefore, in high-risk specific areas or environments with limited operating space (such as narrow spaces such as in a car compartment), the operator can operate in a prone or other non-standing position, thereby improving operational safety and convenience;

[0030] 4. After the priming is completed, the present invention can retain the priming bag due to the pressure-closing ability of the roller pump, and connect the priming liquid to the perfusion circuit through the roller pump. When the patient needs fluid infusion, the amount and speed of fluid infusion can be accurately controlled by rotating the roller pump;

[0031] 5. If the centrifugal pump fails during operation of the present invention, it can be replaced by a roller pump in an emergency to ensure the operation of the system and maintain the patient's vital signs. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 is a schematic diagram of a fast pre-charging system of the present invention;

[0033] Figure 2 This is a pre-charging work roadmap of the fast pre-charging system of Example 1 of the present invention;

[0034] Figure 3 This is a working route diagram of a centrifugal pump in Example 2 of the present invention;

[0035] Figure 4 This is a working route diagram of the roller pump in Example 3 of the present invention;

[0036] Figure 5 This is a fluid replenishment work route map of Example 4 of the present invention;

[0037] Figure 6 It is a structural schematic diagram of the rapid pre-charging system of the present invention.

[0038] Among them, 1. pre-filled bag; 11. liquid outlet; 12. liquid return outlet; 13. liquid outlet pipeline; 14. liquid return pipeline; 2. roller pump; 3. centrifugal pump; 4. oxygenator; 5. first pipeline; 6. second pipeline; 7. third pipeline; 8. fourth pipeline; 9. fifth pipeline; 10. sixth pipeline; 11. first pipe clamp; 12. second pipe clamp; 13. third pipe clamp; 14. fourth pipe clamp. DETAILED DESCRIPTION

[0039] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0040] It should be noted that when an element is referred to as being "fixed to" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "vertical", "horizontal", "left", "right", "upper", "lower" and similar expressions used herein are for illustrative purposes only.

[0041] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "multiple" is two or more, unless otherwise clearly and specifically defined. In this application, " / " means "or".

[0042] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more related listed items.

[0043] At present, since the priming liquid flow has no power, it only relies on the high hanging height of the priming liquid bag to allow the priming liquid to flow into the consumables under the action of gravity, and the filling speed is very low; and because the priming bag is located in front of the centrifugal pump in the pipeline structure, the negative pressure is large during operation after the priming is completed, and it is difficult to control the liquid flow. Therefore, the priming liquid bag can only be removed, and an intravenous route is established to replenish the patient's fluid, which increases the operation and makes the circuit more complicated. However, due to the urgency of the disease, such as 4-6 minutes of brain hypoxia, it usually leads to death, and ECMO consumables need to be priming and exhausting to support operation. Therefore, if the priming time can be compressed as much as possible, it is possible to effectively improve the survival rate of patients after treatment.

[0044] On this basis, the present invention provides an ECMO rapid priming system and a method of use suitable for out-of-hospital emergency rescue. By adding a roller pump as a power source in the priming liquid circuit, the priming liquid can be quickly injected into the pipeline circuit to be priming, with high efficiency and short time.

[0045] The present invention is described in detail below with reference to specific embodiments.

[0046] like Figure 1-6 As shown, this embodiment is applicable to an ECMO rapid priming system for out-of-hospital emergency rescue, and includes a priming bag 1, a roller pump 2, a centrifugal pump 3, and an oxygenator 4 in the direction of priming liquid flow.

[0047] In this embodiment, a liquid outlet 11 and a liquid return port 12 are provided on the pre-filled bag 1. The liquid outlet 11 of the pre-filled bag 1 is connected to the roller pump 2 through the first pipeline 5, that is, one end of the first pipeline 5 is connected to the liquid outlet 11 of the pre-filled bag 1, and the other end is connected to the liquid inlet of the roller pump 2.

[0048] The roller pump 2 is connected to the liquid inlet of the centrifugal pump 3 through the second pipeline 6 , that is, one end of the second pipeline 6 is connected to the liquid outlet of the roller pump 2 , and the other end is connected to the liquid inlet of the centrifugal pump 3 .

[0049] The liquid outlet of the centrifugal pump 3 is connected to the liquid inlet of the oxygenator 4 through the third pipeline 7 , that is, one end of the third pipeline 7 is connected to the liquid outlet of the centrifugal pump 3 , and the other end is connected to the liquid inlet of the oxygenator 4 .

[0050] The liquid outlet of the oxygenator 4 is connected to the liquid return port 12 of the pre-filled bag 1 through the fourth pipeline 8, that is, one end of the fourth pipeline 8 is connected to the liquid outlet of the oxygenator 4, and the other end is connected to the liquid return port 12 of the pre-filled bag 1.

[0051] In this embodiment, a roller pump 2 is added to the pre-fill liquid circuit as a power source, which can quickly inject the pre-fill liquid into the pipeline circuit to be pre-filled, with high efficiency and short time.

[0052] In this embodiment, the second pipeline 6 is connected to the fourth pipeline 8 via the fifth pipeline 9 , that is, one end of the fifth pipeline 9 is connected to the second pipeline 6 , and the other end of the fifth pipeline 9 is connected to the fourth pipeline 8 .

[0053] In this embodiment, a first pipe clamp 11 is provided on the fifth pipeline 9 for connecting or cutting off the flow of liquid in the fifth pipeline 9. Therefore, this embodiment can realize switching between the pre-filling pipeline and the normal perfusion working pipeline.

[0054] In this embodiment, a second pipe clamp 12 is provided on the second pipeline 6, which is used to connect or cut off the flow of liquid in the second pipeline 6. The second pipe clamp 12 is located between the liquid outlet of the roller pump and the connection point between the second pipeline 6 and the fifth pipeline 9. A third pipe clamp 13 is provided on the fourth pipeline 8, which is used to connect or cut off the flow of liquid in the fourth pipeline 8. The third pipe clamp 13 is located between the liquid return port of the pre-filled bag and the connection point between the fourth pipeline 8 and the fifth pipeline 9. In this embodiment, if the centrifugal pump 3 fails during operation, it can also be replaced by the roller pump 2 in an emergency to ensure the operation of the system and maintain the vital signs of the patient.

[0055] In this embodiment, the fourth pipeline 8 is connected to the first pipeline 5 via the sixth pipeline 10 , and a fourth pipe clamp 14 is provided on the sixth pipeline 10 for connecting or cutting off the flow of liquid in the sixth pipeline 10 .

[0056] In this embodiment, the liquid outlet 11 is also connected to a liquid outlet pipe 13, one end of which is connected to the liquid outlet 11, and the other end is detachably connected to the first pipeline 5, and the liquid return port 12 is also connected to a liquid return pipe 14, one end of which is connected to the liquid return port 12, and the other end is detachably connected to the fourth pipeline 8. The detachable connection between the pipelines here is a common technical means, which will not be repeated here.

[0057] In this embodiment, the sixth pipeline 10 is located between the connection point between the liquid outlet pipeline 13 and the first pipeline 5 and the connection point between the liquid return pipeline 14 and the fourth pipeline 8. Therefore, the fourth pipe clamp 14 located on the sixth pipeline 10 is also located between the connection point between the liquid outlet pipeline 13 and the first pipeline 5 and the connection point between the liquid return pipeline 14 and the fourth pipeline 8.

[0058] In this embodiment, the roller pump 2 is arranged on the centrifugal pump 3. Such an arrangement can integrate the system, facilitate the miniaturization of the equipment, and facilitate portability.

[0059] Example 1

[0060] like Figure 2 As shown, in this embodiment, the rapid pre-filling system has a first working state, at which the first tube clamp 11 cuts off the flow of liquid in the fifth pipeline 9, the fourth tube clamp 14 cuts off the flow of liquid in the sixth pipeline 10, the second tube clamp 12 connects the flow of liquid in the second pipeline 6, and the third tube clamp 13 connects the flow of liquid in the fourth pipeline 8. The roller pump serves as the power source of the entire system, so that the liquid in the pre-filling bag 1 performs pre-filling and exhaust of the entire system. The flow direction of the pre-filling liquid is: from the liquid outlet 11 of the pre-filling bag 1 through the liquid outlet pipe 13 and the first pipeline 5 to the roller pump 2, from the roller pump 2 to the second pipeline 6 to the centrifugal pump 3, from the centrifugal pump 3 to the third pipeline 7 to the oxygenator 4, and from the oxygenator 4 to the fourth pipeline 8, the return liquid pipe 14, and the return liquid port 12 to the pre-filling bag 1. Among them, when the pipelines are connected, the tube clamp is in Figure 2 None of them are shown.

[0061] In this embodiment, a roller pump is added as a power source in the pre-fill liquid circuit, which can quickly inject the pre-fill liquid into the pipeline circuit to be pre-filled, with high efficiency and short time. At the same time, the roller pump is used as the power source for pre-filling instead of another centrifugal pump as the power source, because the centrifugal pump cannot be used as a power source when the air is not completely discharged, while the roller pump can generate kinetic energy without being affected by the air, and can be directly pre-filled, further simplifying the operation and improving the pre-filling speed. There is no need to hang the pre-fill liquid bag high for operation. Therefore, in high-risk specific areas or environments with limited operating space (such as narrow spaces such as inside a car), the operator can maintain a non-standing position such as prone to operate, thereby improving operational safety and convenience.

[0062] Example 2

[0063] like Figure 3 As shown, in this embodiment, the rapid pre-filling system has a second working state, at this time, the first pipe clamp 11 connects the flow of liquid in the fifth pipeline 9, the fourth pipe clamp 14 connects the flow of liquid in the sixth pipeline 10, the second pipe clamp 12 cuts off the flow of liquid in the second pipeline 6, and the third pipe clamp 13 cuts off the flow of liquid in the fourth pipeline 8. The fourth pipeline 8 is connected to the human veins and arteries, and the centrifugal pump 3 serves as the power source of the entire system. When the fourth pipeline 8 is connected to the human veins and arteries, the disconnection point on the fourth pipeline 8 is located between the liquid outlet of the oxygenator 4 and the connection point between the fourth pipeline 8 and the fifth pipeline 9. Among them, when the pipelines are connected, the pipe clamp is Figure 3 None of them are shown.

[0064] Example 3

[0065] like Figure 4 As shown, in this embodiment, the rapid prefilling system has a third working state, at this time, the first tube clamp 11 cuts off the flow of liquid in the fifth pipeline 9, the second tube clamp 12 connects the flow of liquid in the second pipeline 6, the third tube clamp 13 connects the flow of liquid in the fourth pipeline 8, and the fourth tube clamp 14 connects the flow of liquid in the sixth pipeline 10. The prefilling bag 1, the liquid outlet pipe 13, and the liquid return pipe 14 are removed, and the fourth pipeline is connected to the human veins and arteries. The roller pump 2 serves as the power source of the entire system. When the fourth pipeline 8 is connected to the human veins and arteries, the disconnection point on the fourth pipeline 8 is located between the liquid outlet of the oxygenator 4 and the connection point between the fourth pipeline 8 and the fifth pipeline 9. Among them, when the pipelines are connected, the tube clamp is in Figure 4 None of them are shown.

[0066] Here, the prefill bag 1, the liquid outlet pipe 13, and the liquid return pipe 14 may not be removed. In order to reduce the entanglement of the pipes, it is recommended to remove them during use.

[0067] In the present embodiment, if the centrifugal pump fails during operation, it can be replaced by a roller pump in an emergency to ensure the operation of the system and maintain the patient's vital signs.

[0068] Example 4

[0069] like Figure 5As shown, in this embodiment, the rapid prefilling system has a fourth working state, at which the third tube clamp 13 cuts off the flow of liquid in the fourth pipeline 8, the first tube clamp 11 connects the flow of liquid in the fifth pipeline 9, the second tube clamp 12 connects the flow of liquid in the second pipeline 6, and the fourth tube clamp 14 connects or cuts off the flow of liquid in the sixth pipeline 10. The fourth pipeline 8 is connected to the human veins and arteries, the centrifugal pump 3 serves as the power source of the entire system, and the roller pump 2 replenishes the liquid in the prefilling bag 1 to the human body. When the fourth pipeline 8 is connected to the human veins and arteries, the disconnection point on the fourth pipeline 8 is located between the liquid outlet of the oxygenator 4 and the connection point between the fourth pipeline 8 and the fifth pipeline 9. Among them, when the pipelines are connected, the tube clamp is in Figure 5 None of them are shown.

[0070] After the priming is completed, the priming bag can be retained due to the pressure-closing capability of the roller pump, and the liquid can be connected to the perfusion circuit through the roller pump. When the patient needs fluid infusion, the amount and speed of fluid infusion can be accurately controlled by rotating the roller pump.

[0071] The method for using the ECMO rapid priming system of the present application comprises the following steps:

[0072] The whole system is pre-filled and exhausted: the first pipe clamp 11 is used to cut off the flow of the liquid in the fifth pipeline 9, the fourth pipe clamp 14 is used to cut off the flow of the liquid in the sixth pipeline 10, the second pipe clamp 12 is used to connect the flow of the liquid in the second pipeline 6, and the third pipe clamp 13 is used to connect the flow of the liquid in the fourth pipeline 8. The roller pump 2 is used as the power source of the whole system, and the liquid in the pre-filled bag 1 is used to pre-fill and exhaust the whole system. The flow direction of the pre-flushing liquid is: from the liquid outlet 11 of the pre-filled bag 1, it flows into the roller pump 2 through the liquid outlet pipe 13 and the first pipeline 5, flows out from the roller pump 2, flows into the centrifugal pump 3 through the second pipeline 6, flows out from the centrifugal pump 3, flows into the oxygenator 4 through the third pipeline 7, and flows out from the oxygenator 4 through the fourth pipeline 8, the liquid return pipe 14, and the liquid return port 12 into the pre-filled bag 1.

[0073] In this embodiment, the following steps are also included:

[0074] After the exhaust is completed, the fourth pipeline 8 is disconnected and connected to the veins and arteries of the human body respectively, so that the first pipe clamp 11 is connected to the flow of liquid in the fifth pipeline 9, the fourth pipe clamp 14 is connected to the flow of liquid in the sixth pipeline 10, the second pipe clamp 12 cuts off the flow of liquid in the second pipeline 6, and the third pipe clamp 13 cuts off the flow of liquid in the fourth pipeline 8. The centrifugal pump 3 serves as the power source of the entire system.

[0075] When the centrifugal pump 3 fails, the first pipe clamp 11 cuts off the flow of liquid in the fifth pipeline 9, the second pipe clamp 12 connects the flow of liquid in the second pipeline 6, the third pipe clamp 14 connects the flow of liquid in the fourth pipeline 8, and the fourth pipe clamp 14 connects the flow of liquid in the sixth pipeline 10. The pre-filled bag 1, the liquid outlet pipe 13, and the liquid return pipe 14 are removed, and the roller pump 2 serves as the power source of the entire system.

[0076] When the human body needs fluid replenishment at the same time, the third pipe clamp 13 is used to cut off the flow of liquid in the fourth pipeline 8, the first pipe clamp 11 is used to connect the flow of liquid in the fifth pipeline 9, the second pipe clamp 12 is used to connect the flow of liquid in the second pipeline 6, and the fourth pipe clamp 14 is used to connect or cut off the flow of liquid in the sixth pipeline 10. The centrifugal pump 3 serves as the power source of the entire system, and the roller pump 2 replenishes the liquid in the pre-filled bag 1 into the human body.

[0077] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0078] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. An ECMO rapid priming system suitable for out-of-hospital emergency rescue, characterized in that: According to the flow direction of the priming liquid, the system includes a priming bag, a roller pump, a centrifugal pump, and an oxygenator in sequence. The priming bag is provided with a liquid outlet and a liquid return port. The liquid outlet of the priming bag is connected with the roller pump through a first pipeline, the roller pump is connected with the liquid inlet of the centrifugal pump through a second pipeline, the liquid outlet of the centrifugal pump is connected with the liquid inlet of the oxygenator through a third pipeline, and the liquid outlet of the oxygenator is connected with the liquid return port of the priming bag through a fourth pipeline.

2. The ECMO rapid priming system suitable for out-of-hospital emergency rescue according to claim 1, characterized in that: The second pipeline is connected to the fourth pipeline through a fifth pipeline, and a first pipe clamp is provided on the fifth pipeline for connecting or cutting off the flow of liquid in the fifth pipeline.

3. The ECMO rapid priming system suitable for out-of-hospital emergency rescue according to claim 2, characterized in that: A second pipe clamp is provided on the second pipeline for connecting or cutting off the flow of liquid in the second pipeline, and the second pipe clamp is located between the roller pump and the connecting point between the second pipeline and the fifth pipeline. A third pipe clamp is provided on the fourth pipeline for connecting or cutting off the flow of liquid in the fourth pipeline, and the third pipe clamp is located between the pre-filled bag and the connecting point between the fourth pipeline and the fifth pipeline.

4. The ECMO rapid priming system suitable for out-of-hospital emergency rescue according to claim 3, characterized in that: The fourth pipeline is connected to the first pipeline through a sixth pipeline, and a fourth pipe clamp is provided on the sixth pipeline for connecting or cutting off the flow of liquid in the sixth pipeline; Preferably, a liquid outlet of the pre-filled bag is connected to a liquid outlet pipe, the liquid outlet pipe is detachably connected to the first pipeline, a liquid return pipe is connected to a liquid return port of the pre-filled bag, the liquid return pipe is detachably connected to the fourth pipeline, and the sixth pipeline is located between the connection point between the liquid outlet pipe and the first pipeline and the connection point between the liquid return pipe and the fourth pipeline; Preferably, the roller pump is arranged on the centrifugal pump.

5. The ECMO rapid priming system suitable for out-of-hospital emergency rescue according to claim 4, characterized in that: The rapid pre-filling system has a first working state, the first pipe clamp cuts off the flow of liquid in the fifth pipeline, the fourth pipe clamp cuts off the flow of liquid in the sixth pipeline, the second pipe clamp connects the flow of liquid in the second pipeline, and the third pipe clamp connects the flow of liquid in the fourth pipeline. The roller pump serves as a power source for the entire system, so that the liquid in the pre-filling bag pre-fills and exhausts the entire system.

6. The ECMO rapid priming system suitable for out-of-hospital emergency rescue according to claim 4, characterized in that: The rapid pre-filling system has a second working state, the first tube clamp connects the flow of liquid in the fifth pipeline, the fourth tube clamp connects the flow of liquid in the sixth pipeline, the second tube clamp cuts off the flow of liquid in the second pipeline, the third tube clamp cuts off the flow of liquid in the fourth pipeline, the fourth pipeline is connected to human veins and arteries, and the centrifugal pump serves as a power source for the entire system.

7. The ECMO rapid priming system suitable for out-of-hospital emergency rescue according to claim 4, characterized in that: The rapid prefilling system has a third working state, the first tube clamp cuts off the flow of liquid in the fifth pipeline, the second tube clamp connects the flow of liquid in the second pipeline, the third tube clamp connects the flow of liquid in the fourth pipeline, the fourth tube clamp connects the flow of liquid in the sixth pipeline, the prefilling bag, the liquid outlet pipeline, and the liquid return pipeline are removed, the fourth pipeline is connected to the human veins and arteries, and the roller pump serves as the power source of the entire system.

8. The ECMO rapid priming system suitable for out-of-hospital emergency rescue according to claim 1, characterized in that: The rapid prefilling system has a fourth working state, the third tube clamp cuts off the flow of liquid in the fourth pipeline, the first tube clamp connects the flow of liquid in the fifth pipeline, the second tube clamp connects the flow of liquid in the second pipeline, the fourth tube clamp connects or cuts off the flow of liquid in the sixth pipeline, the fourth pipeline is connected to human veins and arteries, the centrifugal pump serves as the power source of the entire system, and the roller pump replenishes the liquid in the prefill bag into the human body.

9. A method for using the ECMO rapid priming system according to any one of claims 1 to 8, characterized in that: The steps include: Pre-fill and exhaust the entire system: the first pipe clamp cuts off the flow of liquid in the fifth pipeline, the fourth pipe clamp cuts off the flow of liquid in the sixth pipeline, the second pipe clamp connects the flow of liquid in the second pipeline, and the third pipe clamp connects the flow of liquid in the fourth pipeline. The roller pump serves as the power source of the entire system, and the liquid in the pre-fill bag performs pre-fill and exhaust on the entire system.

10. The method for using the ECMO rapid priming system according to claim 9, characterized in that: The following steps are also included: After the exhaust is completed, the fourth pipeline is disconnected and connected to the vein and artery of the human body respectively, the first pipe clamp is connected to the flow of the liquid in the fifth pipeline, the fourth pipe clamp is connected to the flow of the liquid in the sixth pipeline, the second pipe clamp is cut off the flow of the liquid in the second pipeline, and the third pipe clamp is cut off the flow of the liquid in the fourth pipeline, and the centrifugal pump serves as the power source of the entire system; Preferably, when the centrifugal pump fails, the first pipe clamp is used to cut off the flow of the liquid in the fifth pipeline, the second pipe clamp is used to connect the flow of the liquid in the second pipeline, the third pipe clamp is used to connect the flow of the liquid in the fourth pipeline, the fourth pipe clamp is used to connect the flow of the liquid in the sixth pipeline, the pre-filled bag, the liquid outlet pipeline, and the liquid return pipeline are removed, and the roller pump serves as the power source of the entire system; Preferably, when the human body needs fluid replenishment at the same time, the third tube clamp cuts off the flow of liquid in the fourth pipeline, the first tube clamp connects the flow of liquid in the fifth pipeline, the second tube clamp connects the flow of liquid in the second pipeline, and the fourth tube clamp connects or cuts off the flow of liquid in the sixth pipeline. The centrifugal pump serves as the power source of the entire system, and the roller pump replenishes the liquid in the pre-filled bag into the human body.

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