Implantable neural signal device

Abstract

The invention provides an implantable neural signal device. The implantable neural signal device comprises an acting component and a communication component, the acting assembly comprises a first shell and an acting module arranged in the first shell, at least part of the first shell is implanted into a first organism, the acting module comprises a stimulation module and / or a collection module, the stimulation module is used for applying electrical stimulation to target tissue, and the collection module is used for collecting potential signals of the target tissue. The communication assembly comprises a second shell and a communication module, the first shell is connected with the second shell, the action module is electrically connected with the communication module, the second shell is implanted into a second organism, and the second organism is located on the outer side of the first organism. According to the implantable neural signal device, the action module and the communication module are arranged in the different shells respectively, only at least part of the first shell can be implanted into the first living body, and therefore the size of the implantable neural signal device implanted into the first living body can be effectively reduced, and damage to an implantation area is reduced.

Description

Technical Field

[0001] The present application relates to the technical field of implantable devices, and in particular to an implantable neural signal device. Background Art

[0002] At present, the neural signal system including the implantable neural signal device has been widely used in the medical field. In this system, the implantable neural signal device is implanted into the patient's body to achieve the treatment of the diseased part and the collection of relevant signals of the diseased part. However, at present, the communication part and the collection and stimulation part of the implantable neural signal device are installed in the same shell, which leads to a large volume of the shell. Since the shell of the neural signal device needs to be implanted in the skull, the large volume of the shell will cause greater damage to the implantation area. In addition, the prior art also has a solution in which the communication part and the collection and stimulation part are stacked from top to bottom. This solution will lead to the problem of complicated wiring inside the implantable neural signal device and affect the height of the overall implant device. Summary of the invention

[0003] In response to the above-mentioned technical problems existing in the prior art, the present application provides an implantable neural signal device, which, by arranging the action module and the communication module in different shells respectively, can achieve that only at least a portion of the first shell is implanted into the first biological body, thereby effectively reducing the volume of the implantable neural signal device implanted into the first biological body and reducing the damage caused to the implantation area.

[0004] An embodiment of the present application provides an implantable neural signal device, which includes an action component and a communication component. The action component includes a first shell and an action module disposed in the first shell, at least a portion of the first shell is implanted in a first organism, the action module includes a stimulation module and / or an acquisition module, the stimulation module is used to apply electrical stimulation to a target tissue, and the acquisition module is used to acquire a potential signal of the target tissue. The communication component includes a second shell and a communication module disposed in the second shell, the first shell and the second shell are connected, the action module is electrically connected to the communication module, the second shell is implanted in a second organism, and the second organism is located outside the first organism.

[0005] In some embodiments, the first shell has a first accommodating cavity at least for accommodating the action module, and the second shell has a second accommodating cavity at least for accommodating the communication module, and the first accommodating cavity and the second accommodating cavity are independently arranged.

[0006] In some embodiments, the implantable neural signal device also includes a flexible electrode, the proximal end of the flexible electrode is electrically connected to the action module, and the distal end of the flexible electrode is provided with an electrode site implanted in the target tissue so as to apply electrical stimulation to the target tissue and / or collect the potential signal of the target tissue via the electrode site.

[0007] In some embodiments, the first shell includes a first part and a second part connected to each other, the first part is implanted in the first organism, the second part is implanted in the second organism, and the second shell is connected to the second part.

[0008] In some embodiments, a thickness of the second shell is less than a thickness of the first shell.

[0009] In some embodiments, the first living body is a skull, the second living body is located between the skull and the scalp, and the first shell is connected to the outer side of the skull to be fixed to the skull.

[0010] In some embodiments, at least the first shell implanted in the first biological body is made of metal material; and / or, the second shell is made of non-metal material.

[0011] In some embodiments, the action component further includes a first feedthrough disposed on the first shell, and the action module is electrically connected to the proximal end portion of the flexible electrode through the first feedthrough.

[0012] In some embodiments, the first shell has a distal surface placed in the first biological body, and the first feedthrough is installed on the distal surface of the first shell.

[0013] In some embodiments, the proximal end of the flexible electrode is sealingly connected to the first housing implanted in the first biological body.

[0014] In some embodiments, the action component also includes an electrode cover, which covers the proximal end of the flexible electrode. A pressure connector is provided on the side of the electrode cover facing the flexible electrode, and the pressure connector is used to apply a force to the flexible electrode to make it press against the first feedthrough.

[0015] In some embodiments, the pressure connector includes a seat body, a spring pin and a seal, wherein the seat body is connected to the distal side of the electrode cover, and a mounting hole is provided on the seat body, the spring pin is disposed in the mounting hole, and the seal is disposed on the seat body and surrounds the outer peripheral side of the spring pin.

[0016] In some embodiments, at least part of the first shell casing is provided with a first buffer shell, the first buffer shell is located on a side of the first shell away from the first feedthrough, the second shell casing is provided with a second buffer shell, the first buffer shell and the second buffer shell are installed on each other, or the first buffer shell and the second buffer shell are integrally formed.

[0017] In some embodiments, a plurality of connecting arms are connected to the first shell, and the plurality of connecting arms are used to cooperate to fix at least a portion of the first shell within the first biological body, and the plurality of connecting arms are arranged at intervals around the outer side of the first shell.

[0018] In some embodiments, the active component further includes a circuit board and a power supply module disposed in the first shell, and the power supply module is electrically connected to the circuit board; wherein the power supply module includes a power supply battery and / or a power supply circuit.

[0019] In some embodiments, the communication module includes a charging coil and / or a Bluetooth module to supply power to the power supply module via the charging coil and / or to transmit information to the action module via the Bluetooth module.

[0020] In some embodiments, the communication module includes a charging coil and a Bluetooth module, the antenna of the Bluetooth module is wound around the outer circumference of the charging coil, and is sealed and fixed with the charging coil in the second shell.

[0021] In some embodiments, a second feedthrough is provided on a side of the first shell facing the second shell, and the action module is electrically connected to the communication module through the second feedthrough.

[0022] In some embodiments, a connecting portion is provided on a side of the first shell facing the second shell, and the second shell is connected to the connecting portion.

[0023] In some embodiments, a step portion is configured on one side of the first shell facing the second shell, the step portion has a side wall and a bottom wall, the second shell abuts against the side wall of the step portion, and the bottom of the second shell is supported by the bottom wall of the step portion.

[0024] In some embodiments, the flexible electrode is configured in a sheet shape, and the flexible electrode further comprises a lead connecting portion, and the proximal end portion and the distal end portion are electrically connected via the lead connecting portion.

[0025] Compared with the prior art, the beneficial effect of the embodiment of the present application is that: the present application separately sets the first shell of the action component and the second shell of the communication component, so that the action module and the communication module are placed in different shells respectively, and it can be realized that only at least part of the first shell is implanted into the first organism, thereby effectively reducing the volume of the implanted neural signal device implanted into the first organism and reducing the damage caused to the implantation area. In addition, the communication module of the communication component is located in the second shell implanted in the second organism, which can improve the signal strength and data transmission efficiency of the communication module. In addition, compared with the current scheme of stacking the communication part and the collection and stimulation part from top to bottom, the present application can reduce the overall structural thickness of the implanted neural signal device by designing two independent shells, namely the connected first shell and the second shell, and can reduce the complexity of the internal wiring of the implanted neural signal device, simplify the structural design of the implanted neural signal device, and make the structure more reasonable. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In the drawings, which are not necessarily drawn to scale, the same reference numerals may describe similar components in different views. The drawings generally illustrate various embodiments by way of example and not limitation, and together with the description and claims, serve to illustrate the disclosed embodiments. When appropriate, the same reference numerals are used throughout the drawings to refer to the same or similar parts. Such embodiments are illustrative and are not intended to be exhaustive or exclusive embodiments of the present apparatus or method.

[0027] Figure 1 This is a schematic structural diagram of the implantable neural signal device from a first perspective according to an embodiment of the present application; Figure 2 This is an exploded view of the local structure of the implantable neural signal device according to an embodiment of the present application; Figure 3 This is an exploded view of the implantable neural signal device according to an embodiment of the present application; Figure 4 This is a schematic structural diagram of the implantable neural signal device from a second perspective according to an embodiment of the present application; Figure 5 This is a schematic diagram of a first partial structure of an implantable neural signal device according to an embodiment of the present application; Figure 6 This is a schematic diagram of a second partial structure of the implantable neural signal device according to an embodiment of the present application; Figure 7 This is a schematic diagram of the structure of the pressure connector of the implantable neural signal device according to an embodiment of the present application.

[0028] The components indicated by the reference numerals in the figures are: 1. Functional component; 11. First shell; 12. Connecting arm; 13. Circuit board; 14. Power supply module; 2. Communication component; 21. Second shell; 22. Communication module; 23. Charging coil; 24. Bluetooth module; 3. Flexible electrode; 31. Proximal end; 32. Distal end; 33. Lead connection; 4. First feedthrough; 5. Electrode cover; 6. Pressure connector; 61. Seat; 62. Spring pin; 63. Sealing member; 7. Second feedthrough; 8. First buffer shell. DETAILED DESCRIPTION

[0029] It should be understood that various modifications may be made to the embodiments herein. Therefore, the above description should not be considered as limiting, but merely as an example of an embodiment. Other modifications within the scope and spirit of the present application will occur to those skilled in the art.

[0030] The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate embodiments of the present application and, together with the general description of the present application given above and the detailed description of the embodiments given below, serve to explain the principles of the present application.

[0031] These and other characteristics of the present application will become apparent from the following description of a preferred form of embodiment given as a non-limiting example with reference to the accompanying drawings.

[0032] It should also be understood that although the present application has been described with reference to some specific examples, those skilled in the art will be able to readily implement many other equivalent forms of the present application.

[0033] The above and other aspects, features and advantages of the present application will become more apparent in view of the following detailed description when taken in conjunction with the accompanying drawings.

[0034] Specific embodiments of the present application are described hereinafter with reference to the accompanying drawings; however, it should be understood that the embodiments are merely examples of the present application, which may be implemented in a variety of ways. Well-known and / or repeated functions and structures are not described in detail to avoid unnecessary or redundant details that obscure the present application. Therefore, the specific structural and functional details herein are not intended to be limiting, but merely serve as the basis and representative basis for the claims to teach those skilled in the art to use the present application in a variety of ways with substantially any suitable detailed structure.

[0035] This specification may use the phrases "in one embodiment," "in another embodiment," "in yet another embodiment," or "in other embodiments," all of which may refer to one or more of the same or different embodiments according to the present application.

[0036] In the present application, the term "proximal" is intended to mean a side close to an operator (e.g., a doctor) performing an implantation operation, and the term "distal" is intended to mean a side close to a target area of ​​an implantable neural signal device to be implanted. Similarly, the term "proximal end" is intended to mean an end close to an operator (e.g., a doctor) performing an implantation operation, and the term "distal end" is intended to mean a side close to a target area of ​​an implantable neural signal device to be implanted.

[0037] All terms (including technical terms or scientific terms) used in this application have the same meaning as those understood by ordinary technicians in the field to which this application belongs, unless otherwise specifically defined. It should also be understood that terms defined in general dictionaries should be interpreted as having a meaning consistent with their meaning in the context of the relevant technology, and should not be interpreted in an idealized or extremely formal sense, unless explicitly defined herein. Techniques, methods and equipment known to ordinary technicians in the relevant field may not be discussed in detail, but where appropriate, the techniques, methods and equipment should be considered as part of the specification.

[0038] The present application embodiment provides an implantable neural signal device. Figures 1 to 3 As shown, the implantable neural signal device includes an action component 1 and a communication component 2. The action component 1 includes a first shell 11 and an action module disposed in the first shell 11, at least a portion of the first shell 11 is implanted in a first organism, the action module includes a stimulation module and / or a collection module, the stimulation module is used to apply electrical stimulation to the target tissue, and the collection module is used to collect the potential signal of the target tissue. The communication component 2 includes a second shell 21 and a communication module 22 disposed in the second shell 21, the first shell 11 and the second shell 21 are connected, the action module is electrically connected to the communication module 22, the second shell 21 is implanted in a second organism, and the second organism is located outside the first organism.

[0039] By placing the above-mentioned action module in the first shell 11 and the communication module 22 in the second shell 21, it is possible to place the action module and the communication module 22 in different shells. The first shell 11 and the second shell 21 can be understood as two independent shells, and there is a connection relationship between the two. By setting up the independent first shell 11 and the second shell 21, the modularization of the action component 1 and the modularization of the communication component 2 can be achieved. After completing the assembly of the action component 1 and the communication component 2, the assembly between the action component 1 and the communication component 2 is performed, such as connecting the first shell 11 and the second shell 21, and electrically connecting the action module and the communication module 22.

[0040] The first shell 11 is at least partially implanted in the first organism, and the second shell 21 is implanted in the second organism located outside the first organism. This enables the communication module 22 in the second shell 21 to be located outside the first organism, thereby reducing the groove area of ​​the first organism and achieving the purpose of reducing damage.

[0041] Moreover, compared with the solution of implanting the communication module 22 into the first organism, the present application implants the communication module 22 into the second organism located outside the first organism, which can reduce the interference to the communication module 22 and achieve the purpose of improving the signal strength and data transmission efficiency of the communication module 22.

[0042] An inner bracket may be provided in the first housing 11, and the inner bracket is used to support the electronic components in the first housing 11, such as the action module in the first housing 11, and also as the circuit board 13 and / or the power supply module 14 in the first housing 11 mentioned below. The inner bracket can be used to install and fix the electronic components in the first housing 11 to ensure the stability of the internal structure of the action assembly 1.

[0043] The first shell 11 may be constructed as a structure with an inner cavity sealed by connecting a plurality of sub-shells. Exemplarily, the first shell 11 is a structure with an inner cavity sealed by splicing two sub-shells.

[0044] The first shell 11 and the second shell 21 may be sealed and connected via a sealing connector. The sealing connector may be made of epoxy resin or other insulating materials, which is not specifically limited in the present application.

[0045] The shape of the first shell 11 can be cylindrical, truncated cone or other shapes. The shape of the bottom surface of the second shell 21 can be circular or elliptical. The present application sets the first shell 11 of the action component 1 and the second shell 21 of the communication component 2 respectively, so that the action module and the communication module 22 are placed in different shells respectively, so that only at least part of the first shell 11 can be implanted into the first organism, thereby effectively reducing the volume of the implanted neural signal device implanted into the first organism and reducing the damage to the implantation area. In addition, the communication module 22 of the communication component 2 is located in the second shell 21 implanted in the second organism, which can improve the signal strength and data transmission efficiency of the communication module 22. In addition, compared with the current scheme of stacking the communication part and the collection and stimulation part from top to bottom, the present application can reduce the overall structural thickness of the implanted neural signal device by designing two independent shells, namely the connected first shell 11 and the second shell 21, and can reduce the complexity of the internal wiring of the implanted neural signal device, simplify the structural design of the implanted neural signal device, and make the structure more reasonable.

[0046] In some embodiments, the first housing 11 has a first accommodating cavity at least for accommodating the action module, and the second housing 21 has a second accommodating cavity at least for accommodating the communication module 22, and the first accommodating cavity and the second accommodating cavity are independently arranged.

[0047] In this way, the action module and the communication module 22 can be respectively accommodated by the independently arranged first accommodating cavity and the second accommodating cavity, so that the action module and the communication module 22 can be independently arranged respectively. Compared with implanting the communication module 22 into the first biological body, by implanting the communication module 22 into the second biological body outside the first biological body, it is beneficial to reduce the size of the first shell 11 implanted in the first biological body, thereby achieving the purpose of reducing damage to the implantation area.

[0048] The above-mentioned first accommodating chamber and the second accommodating chamber are independently arranged, which can be understood as the first accommodating chamber and the second accommodating chamber are not connected, so as to realize the independent arrangement of the active component 1 and the communication component 2.

[0049] In some embodiments, Figures 1 to 4 As shown, the implantable neural signal device further includes a flexible electrode 3, which can be made of a flexible material. The proximal end 31 of the flexible electrode 3 is electrically connected to the action module, and the distal end 32 of the flexible electrode 3 is provided with an electrode site implanted in the target tissue, so as to apply electrical stimulation to the target tissue and / or collect the potential signal of the target tissue via the electrode site. The flexible electrode 3 can better adapt to the shape and movement of the neural tissue, thereby reducing the mechanical pressure and damage to the surrounding tissue.

[0050] The flexible electrode 3 may be connected to the distal side of the first housing 11 placed in the first biological body, or may be connected to the side of the first housing 11, which side may be understood as a surface adjacent to the distal side. Figure 4 As shown, Figure 4 The flexible electrode 3 shown in the figure is connected to the distal side of the first shell 11 placed in the first biological body.

[0051] The proximal portion 31 of the flexible electrode 3 is electrically connected to the action module, and the electrode sites on the distal portion 32 electrically connected to the proximal portion 31 can realize the information collection of the target tissue and the function of electrical stimulation.

[0052] In some embodiments, Figures 1 to 4 As shown, the flexible electrode 3 is configured in a sheet shape, and the flexible electrode 3 further includes a lead connection portion 33, and the proximal portion 31 and the distal portion 32 are electrically connected via the lead connection portion 33. The proximal portion 31, the lead connection portion 33 and the distal portion 32 are sequentially arranged along the length direction of the flexible electrode 3.

[0053] The flexible electrode 3 may adopt a multi-layer structure, such as being formed by stacked insulating layers and conductive layers. The present application does not specifically limit the structure of the flexible electrode 3.

[0054] In some embodiments, Figures 1 to 4 As shown, the first shell 11 includes a first part and a second part connected to each other, the first part is implanted in a first organism, the second part is implanted in a second organism, and the second shell 21 is connected to the second part.

[0055] In this way, the first shell 11 can be partially implanted into the first organism by implanting the first part into the first organism and the second part into the second organism, so as to effectively reduce the volume of the first shell 11 implanted into the first organism, thereby reducing damage to the implantation area.

[0056] The first shell 11 and the second shell 21 may be connected in a detachable manner or by welding, and the present application does not make any specific limitation thereto, and it is sufficient that the sealing of the connection between the first shell 11 and the second shell 21 can be ensured.

[0057] The shape of the first part may be cylindrical, truncated cone, etc. When the shape of the first part is cylindrical, the diameter of the first part may range from 28 mm to 32 mm, preferably 30 mm.

[0058] The first part and / or the second part may be provided with a positioning surface, and the positioning surface is used to abut against the first biological body to achieve positioning of the first shell 11.

[0059] In some embodiments, the thickness of the second shell 21 is less than the thickness of the first shell 11, so as to reduce the thickness of the second shell 21 implanted in the second organism as much as possible, so that the first shell 11 and the second shell 21 can be more reasonably implanted in the second organism, reducing damage to the second organism.

[0060] Specifically, the proximal side surface of the first shell 11 and the proximal side surface of the second shell 21 may be located in the same plane, that is, the upper surface of the first shell 11 and the upper surface of the second shell 21 may be flush with each other.

[0061] The thickness of the first shell 11 may range from 6 mm to 8 mm. The thickness of the second shell 21 may range from 2 mm to 4 mm, preferably 3 mm.

[0062] The edges of the first shell 11 and the second shell 21 may be processed to have a smooth transition so as to reduce damage to the target tissue in the implantation area.

[0063] In some embodiments, the first living body is a skull, the second living body is located between the skull and the scalp, and the first shell 11 is connected to the outer side of the skull to be fixed to the skull.

[0064] In some embodiments, at least the first shell 11 implanted in the first biological body is made of metal material; and / or the second shell 21 is made of non-metal material.

[0065] In this way, the interference of the metal material on the communication module 22 in the second housing 21 can be reduced, that is, the signal shielding or eddy current caused by the metal can be reduced, thereby improving the signal strength and data transmission efficiency of the communication module 22.

[0066] The metal material used for the first shell 11 implanted in at least the first biological body may be titanium alloy or other metal materials, such as stainless steel, aluminum alloy, etc., which have excellent strength, rigidity and biocompatibility. The present application does not make any specific limitation on the metal material used for the first shell 11, as long as it can be implanted in the biological body.

[0067] Optionally, the first shell 11 that is not implanted in the first biological body may be made of a non-metallic material, and the non-metallic material should have good corrosion resistance, biocompatibility and processability, such as silicone.

[0068] Optionally, the first shell 11 not implanted in the first organism can be made of metal material. Specifically, the first shell 11 is made of the same metal material, such as titanium alloy.

[0069] In some embodiments, Figure 4 and Figure 5 As shown, the action assembly 1 further includes a first feedthrough 4 provided on the first housing 11, and the action module is electrically connected to the proximal end 31 of the flexible electrode 3 via the first feedthrough 4. Thus, the first feedthrough 4 can realize a stable electrical connection between the flexible electrode 3 and the action module.

[0070] The first shell 11 may be provided with a first feedthrough slot, and the first feedthrough member 4 may be installed in the first feedthrough slot. The first feedthrough member 4 may be stably installed through the first feedthrough slot, and the structure of the active component 1 may be made more reasonable.

[0071] The first feedthrough 4 may include a mounting base, an insulating sleeve, and a conductor. The mounting base may be sealed and connected to the first shell 11, specifically by welding. The insulating sleeve is embedded in the mounting base, and the conductor extends out of the first shell 11 through the insulating sleeve to be electrically connected to the communication module 22 in the second shell 21. The insulating sleeve may be made of ceramic or other insulating materials.

[0072] In some embodiments, Figure 4As shown, the first shell 11 has a distal side placed in the first biological body, and the first feedthrough 4 is installed on the distal side of the first shell 11. By installing the first feedthrough 4 on the distal side of the first shell 11, the flexible electrode 3 connected to the first feedthrough 4 can be closer to the target tissue, which is beneficial to the implantation of the flexible electrode 3.

[0073] In some other embodiments, such as Figure 5 As shown, the first feed-through 4 may be disposed on a side surface of the first shell 11 adjacent to the distal side surface.

[0074] Specifically, a step-shaped mounting structure may be formed on the first shell 11 , and the step-shaped mounting structure has a side wall and a bottom wall. The first feed-through member 4 may be located on the bottom wall of the mounting structure.

[0075] In some embodiments, the proximal portion 31 of the flexible electrode 3 is sealed to the first shell 11 implanted in the first biological body to prevent external tissue from invading, thereby achieving a good sealing effect on the flexible electrode 3 and effectively improving the sealing performance.

[0076] Optionally, the proximal portion 31 of the flexible electrode 3 and the first housing 11 implanted in the first biological body may be sealed by injecting insulating material.

[0077] Optionally, the proximal portion 31 of the flexible electrode 3 and the first housing 11 implanted in the first biological body may be sealed by coating an insulating material.

[0078] Optionally, the insulating material may be epoxy resin or other insulating materials, which is not specifically limited in the present application.

[0079] In some embodiments, Figure 7 As shown, the action component 1 also includes an electrode cover 5, which covers the proximal end 31 of the flexible electrode 3. A pressure connector 6 is provided on the side of the electrode cover 5 facing the flexible electrode 3, and the pressure connector 6 is used to apply a force to the flexible electrode 3 to make it press against the first feedthrough 4.

[0080] In this way, a stable force can be applied to the flexible electrode 3 through the above-mentioned pressure connector 6, so that the flexible electrode 3 can be stably abutted against the first feedthrough 4, effectively improving the conduction effect at the contact point between the flexible electrode 3 and the first feedthrough 4, thereby ensuring that the flexible electrode 3 can be stably electrically connected to the action module through the first feedthrough 4.

[0081] In the case where the action module includes a stimulation module, since a simulator will be first used to electrically connect the flexible electrode 3 for a simulation operation, and after the simulation operation confirms various parameters, an implantable neural signal device will be used to perform a formal implantation operation. Therefore, the flexible electrode 3 and the action component 1 will be installed before the formal implantation operation. By using the above-mentioned pressure connector 6, when the flexible electrode 3 is installed on the action component 1, a force can be applied to the flexible electrode 3 to make it press against the first feedthrough 4, thereby ensuring that the flexible electrode 3 can achieve a stable electrical connection relationship with the action module through the first feedthrough 4.

[0082] In some embodiments, the pressure connector 6 can be used to apply an elastic force to the flexible electrode 3, so that the flexible electrode 3 can stably press against the first feedthrough 4. In some other embodiments, the pressure connector 6 can move under the control of a control signal to act on the flexible electrode 3, so as to apply a force to the flexible electrode 3 to press against the first feedthrough 4, such as the pressure connector 6 includes a retractable structure, which can perform a retractable movement to act on the flexible electrode 3 after receiving the control signal.

[0083] The electrode cover 5 can be mounted on the distal side of the first shell 11. Specifically, the electrode cover 5 can be connected to the first shell 11 in a detachable connection manner, such as the electrode cover 5 is connected to the first shell 11 in a pivot connection manner, or the electrode cover 5 is provided with a mounting hole, and a mounting screw can be installed in the mounting hole to achieve disassembly and assembly with the first shell 11. In some other embodiments, the electrode cover 5 can be connected to the first shell 11 in a sliding connection manner, and the present application does not specifically limit the connection method between the electrode cover 5 and the first shell 11.

[0084] The electrode cover 5 can be made of one or more of the following materials: polyetheretherketone, epoxy resin.

[0085] After the flexible electrode 3 and the first feedthrough 4 are connected, an insulating material may be used for filling to ensure the installation sealing of the flexible electrode 3 and the first feedthrough 4 .

[0086] In some embodiments, Figure 7 As shown, the pressure connector 6 includes a seat body 61, a spring pin 62 and a seal 63. The seat body 61 is connected to the far side of the electrode cover 5, and a mounting hole is provided on the seat body 61. The spring pin 62 is provided in the mounting hole. The seal 63 is provided on the seat body 61 and surrounds the outer peripheral side of the spring pin 62.

[0087] In this way, a stable force can be applied to the flexible electrode 3 through the elastic pin 62 installed on the seat body 61, and the installation sealing between the pressure connector 6, the flexible electrode 3 and the first feed-through 4 can be ensured by the sealing member 63.

[0088] The elastic pins 62 can be arranged one-to-one corresponding to the contacts of the proximal end portion 31 of the flexible electrode 3 to ensure that each contact of the proximal end portion 31 of the flexible electrode 3 can stably abut against the first feedthrough 4, thereby ensuring the connection stability at the contact.

[0089] In some embodiments, Figures 1 to 3 As shown, at least part of the first shell 11 is provided with a first buffer shell 8, the first buffer shell 8 is located on the side of the first shell 11 away from the first feedthrough 4, and the second shell 21 is provided with a second buffer shell, the first buffer shell 8 and the second buffer shell are installed with each other, or the first buffer shell 8 and the second buffer shell are formed as one piece.

[0090] In this way, by providing the first buffer shell 8 and the second buffer shell, a buffering protection effect can be provided to the implantation area, thereby achieving the purpose of reducing damage to the target tissue.

[0091] The first buffer shell 8 and the second buffer shell may be made of a flexible material with a certain elasticity, and the material should be corrosion-resistant, biocompatible and machinable, such as silicone.

[0092] The first buffer shell 8 may cover a portion or all of the outside of the first shell 11 , and the second buffer shell may cover a portion or all of the outside of the second shell 21 .

[0093] In some embodiments, Figures 1 to 4 As shown, a plurality of connecting arms 12 are connected to the first shell 11 , and the plurality of connecting arms 12 are used to cooperate to fix at least a portion of the first shell 11 in the first biological body, and the plurality of connecting arms 12 are arranged at intervals around the outer side of the first shell 11 .

[0094] In this way, the first shell 11 can be stably fixed on the first biological body through the connecting arm 12, thereby achieving installation stability of the active component 1.

[0095] Optionally, the connecting arm 12 may be integrally formed with the first housing 11, or may be detachably connected to the first housing 11, which is not specifically limited in the present application. When the connecting arm 12 is detachably connected to the first housing 11, the connecting arm 12 may be independent of the first housing 11, so that the length of the connecting arm 12 used may be adjusted as needed, providing the operator with a variety of size options.

[0096] Optionally, the connecting arm 12 may be made of a metal material, such as a titanium alloy, or other metal materials, such as stainless steel, aluminum alloy, etc., which have excellent strength, rigidity and biocompatibility. The present application does not specifically limit the metal material used for the connecting arm 12, as long as it can be implanted in a living body.

[0097] Optionally, a mounting hole may be provided on the end of the connecting arm 12 away from the first shell 11, and a fastener may be passed through the mounting hole to fix the first shell 11 to the first organism through the fastener. If the fastener is a bolt, the first shell 11 can be fixed to the first organism through the connection with the bolt.

[0098] In some embodiments, Figure 3 As shown, the action component 1 also includes a circuit board 13 and a power supply module 14 disposed in the first housing 11. The power supply module 14 is electrically connected to the circuit board 13; the power supply module 14 includes a power supply battery and / or a power supply circuit. The action module can be disposed on the circuit board 13, or can be independent of the circuit board 13 and electrically connected to the circuit board 13.

[0099] In this way, the power supply module 14 can be used to realize continuous power supply using a power supply battery, or the power supply circuit can be used while charging.

[0100] The circuit board 13 and the power supply module 14 may be fixed to the first housing 11 via an internal bracket, or may be fixedly installed by other brackets, which is not specifically limited in the present application.

[0101] In some embodiments, Figure 2 and Figure 3 As shown, the communication module 22 includes a charging coil 23 and / or a Bluetooth module 24 to supply power to the power supply module 14 via the charging coil 23 and / or to transmit information to the action module via the Bluetooth module 24 .

[0102] When the communication module 22 includes a charging coil 23 and a Bluetooth module 24, the charging coil 23 and the Bluetooth module 24 do not need to be placed in the first shell 11, thereby achieving the purpose of reducing the size of the first shell 11 as much as possible, thereby effectively reducing the volume of the first shell 11 implanted in the first biological body and reducing damage to the implantation area.

[0103] When the communication module 22 does not include the charging coil 23 , the charging coil 23 may be disposed in the first housing 11 so as to directly supply power to the circuit board 13 and the power supply module 14 in the first housing 11 through the charging coil 23 .

[0104] When the communication module 22 does not include the Bluetooth module 24 , the Bluetooth module 24 may be disposed in the first housing 11 to directly communicate with the circuit board 13 in the first housing 11 .

[0105] In some embodiments, Figure 2 and Figure 3As shown, the communication module 22 includes a charging coil 23 and a Bluetooth module 24 . The antenna of the Bluetooth module 24 is wound around the outer circumference of the charging coil 23 and is sealed and fixed with the charging coil 23 in the second shell 21 .

[0106] The structural design of the charging coil 23 and the Bluetooth module 24 is relatively reasonable, and the thickness of the second shell 21 can be reduced as much as possible, thereby reducing the damage caused to the implantation area.

[0107] In some embodiments, Figure 6 As shown, a second feedthrough 7 is provided on one side of the first housing 11 facing the second housing 21, and the action module is electrically connected to the communication module 22 via the second feedthrough 7. Thus, the second feedthrough 7 can realize a stable connection between the communication module 22 and the action module.

[0108] Optionally, a second feedthrough slot may be provided on the first shell 11, and the second feedthrough member 7 may be installed in the second feedthrough slot. The second feedthrough slot may be used to stably install the second feedthrough member 7 and make the structural design of the action component 1 more reasonable.

[0109] In some embodiments, a connection portion is disposed on one side of the first housing 11 facing the second housing 21, and the second housing 21 is connected to the connection portion. In this way, the first housing 11 and the second housing 21 can be stably connected through the connection portion.

[0110] The connecting portion may be integrally formed with the first shell 11 , or may be detachably connected to the first shell 11 , and the present application does not impose any specific limitation thereto, as long as a stable connection between the first shell 11 and the second shell 21 is achieved.

[0111] In some embodiments, Figure 6 As shown, a step portion is configured on one side of the first housing 11 facing the second housing 21, the step portion having a side wall and a bottom wall, the second housing 21 abuts against the side wall of the step portion, and the bottom of the second housing 21 is supported by the bottom wall of the step portion. In this way, a stable connection between the first housing 11 and the second housing 21 can be achieved through the side wall and the bottom wall of the step portion.

[0112] In addition, although exemplary embodiments have been described herein, the scope includes any and all embodiments based on the present application with equivalent elements, modifications, omissions, combinations (e.g., schemes that cross various embodiments), adaptations or changes. The elements in the claims will be interpreted broadly based on the language used in the claims, and are not limited to the examples described in this specification or during the practice of the present application, and the examples will be interpreted as non-exclusive.

[0113] The above description is intended to be illustrative rather than restrictive. For example, the above examples (or one or more schemes thereof) may be used in combination with each other. For example, a person of ordinary skill in the art may use other embodiments when reading the above description. In addition, in the above-mentioned specific embodiments, various features may be grouped together to simplify the present application. This should not be interpreted as an intention that a disclosed feature that is not required to be protected is necessary for any claim. On the contrary, the subject matter of the present application may be less than all the features of a particular disclosed embodiment. Thus, the claims are incorporated herein as examples or embodiments in the specific embodiments, wherein each claim is independently a separate embodiment, and it is considered that these embodiments may be combined with each other in various combinations or arrangements. The scope of the present application should be determined with reference to the attached claims and the full scope of equivalent forms granted by these claims.

[0114] The above embodiments are only exemplary embodiments of the present application and are not intended to limit the present application. The protection scope of the present application is defined by the claims. Those skilled in the art may make various modifications or equivalent substitutions to the present application within the essence and protection scope of the present application, and such modifications or equivalent substitutions shall also be deemed to fall within the protection scope of the present application.

Claims

1. An implantable neural signal device, characterized in that: include: An action component, comprising a first shell and an action module arranged in the first shell, at least a portion of the first shell is implanted in a first organism, the action module comprises a stimulation module and / or a collection module, the stimulation module is used to apply electrical stimulation to a target tissue, and the collection module is used to collect a potential signal of the target tissue; The communication component includes a second shell and a communication module arranged in the second shell, the first shell and the second shell are connected, the action module is electrically connected to the communication module, the second shell is implanted in a second organism, and the second organism is located outside the first organism.

2. The implantable neural signal device according to claim 1, characterized in that: The first shell has a first accommodating cavity at least for accommodating the action module, and the second shell has a second accommodating cavity at least for accommodating the communication module, and the first accommodating cavity and the second accommodating cavity are independently arranged.

3. The implantable neural signal device according to claim 1, characterized in that: The implantable neural signal device also includes a flexible electrode, the proximal end of the flexible electrode is electrically connected to the action module, and the distal end of the flexible electrode is provided with an electrode site implanted in the target tissue so as to apply electrical stimulation to the target tissue and / or collect the potential signal of the target tissue via the electrode site.

4. The implantable neural signal device according to claim 1, characterized in that: The first shell includes a first part and a second part connected to each other, the first part is implanted in the first organism, the second part is implanted in the second organism, and the second shell is connected to the second part.

5. The implantable neural signal device according to claim 1, characterized in that: The thickness of the second shell is smaller than the thickness of the first shell.

6. The implantable neural signal device according to claim 1, characterized in that: The first living body is a skull, the second living body is located between the skull and the scalp, and the first shell is connected to the outer side of the skull to be fixed to the skull.

7. The implantable neural signal device according to claim 1, characterized in that: At least the first shell implanted in the first biological body is made of metal material; and / or, The second shell is made of non-metallic material.

8. The implantable neural signal device according to claim 3, characterized in that: The action assembly further includes a first feedthrough disposed on the first shell, and the action module is electrically connected to the proximal end portion of the flexible electrode through the first feedthrough.

9. The implantable neural signal device according to claim 8, characterized in that: The first shell has a distal side placed in the first biological body, and the first feedthrough is installed on the distal side of the first shell.

10. The implantable neural signal device according to claim 3, characterized in that: The proximal end portion of the flexible electrode is sealed and connected to the first housing implanted in the first biological body.

11. The implantable neural signal device according to claim 8, characterized in that: The action component also includes an electrode cover, which covers the proximal end of the flexible electrode. A pressure connector is provided on the side of the electrode cover facing the flexible electrode, and the pressure connector is used to apply a force to the flexible electrode to make it press against the first feedthrough.

12. The implantable neural signal device according to claim 11, characterized in that: The pressure connector includes a seat body, a spring pin and a seal. The seat body is connected to the distal side of the electrode cover and is provided with a mounting hole. The spring pin is arranged in the mounting hole. The seal is arranged on the seat body and surrounds the outer peripheral side of the spring pin.

13. The implantable neural signal device according to claim 8, characterized in that: At least part of the first shell is covered with a first buffer shell, the first buffer shell is located on a side of the first shell away from the first feedthrough, the second shell is covered with a second buffer shell, the first buffer shell and the second buffer shell are installed on each other, or the first buffer shell and the second buffer shell are integrally formed.

14. The implantable neural signal device according to claim 1 or 6, characterized in that: The first shell is connected to a plurality of connecting arms, and the plurality of connecting arms are used to cooperate to fix at least a portion of the first shell within the first biological body, and the plurality of connecting arms are arranged at intervals around the outer side of the first shell.

15. The implantable neural signal device according to claim 1, characterized in that: The functional component also includes a circuit board and a power supply module disposed in the first shell, and the power supply module is electrically connected to the circuit board; wherein the power supply module includes a power supply battery and / or a power supply circuit.

16. The implantable neural signal device according to claim 15, characterized in that: The communication module includes a charging coil and / or a Bluetooth module, so as to supply power to the power supply module via the charging coil, and / or transmit information to the action module via the Bluetooth module.

17. The implantable neural signal device according to claim 16, characterized in that: The communication module includes a charging coil and a Bluetooth module. The antenna of the Bluetooth module is wound around the outer circumference of the charging coil and is sealed and fixed with the charging coil in the second shell.

18. The implantable neural signal device according to claim 1, characterized in that: A second feedthrough is provided on a side of the first shell facing the second shell, and the action module is electrically connected to the communication module through the second feedthrough.

19. The implantable neural signal device according to claim 1, characterized in that: A connecting portion is provided on a side of the first shell facing the second shell, and the second shell is connected to the connecting portion.

20. The implantable neural signal device according to claim 1, characterized in that: A step portion is configured on one side of the first shell facing the second shell. The step portion has a side wall and a bottom wall. The second shell abuts against the side wall of the step portion, and the bottom of the second shell is supported by the bottom wall of the step portion.

21. The implantable neural signal device according to claim 3, characterized in that: The flexible electrode is configured in a sheet shape and further comprises a lead connecting portion, and the proximal end portion and the distal end portion are electrically connected via the lead connecting portion.

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