Reading device for chemiluminescence immunity analyzer

Abstract

The invention relates to the technical field of chemiluminescence immunoassay, in particular to a reading device for a chemiluminescence immunoassay instrument, and solves the problem that the detection precision is influenced by condensate water of a reagent bin gate in the prior art. The invention discloses a reading device for a chemiluminescence immunoassay analyzer. The reading device comprises a bin body, a transverse displacement assembly and a bin cover, the fan is synchronously started to form negative pressure, and the through groove design of the bin cover and the water absorption function of the adsorption sponge are combined, so that condensed water in the bin is effectively managed, the pollution risk is avoided, and the detection precision and stability are improved. Meanwhile, vibration impact is reduced through the arc-shaped opening and closing bin cover design, reagent loss is reduced, and the service life is prolonged.

Description

Technical Field

[0001] The invention relates to the technical field of chemiluminescent immunoassay, and in particular to a reading device for a chemiluminescent immunoassay analyzer. Background Art

[0002] Chemiluminescent immunoassay (CLIA) is an advanced immunoassay method that directly labels antigens or antibodies with chemiluminescent agents, uses chemiluminescent substances to form excited intermediates under the action of catalysts and oxidants, and releases photons when the intermediates return to a stable ground state, thereby achieving quantitative detection of trace antigens or antibodies. This method occupies an important position in clinical medical diagnosis due to its high sensitivity, high specificity and wide applicability. As the core equipment for performing CLIA, the chemiluminescent immunoassay reader (i.e., chemiluminescent analysis module) is crucial for accurately acquiring and analyzing test data.

[0003] In a chemiluminescent immunoassay analyzer, the reading module not only needs to accurately measure the light quantum yield, but also needs to ensure the stability and repeatability of the detection process. To achieve this goal, the analyzer is usually equipped with an incubation chamber and a reagent chamber. The incubation chamber is used to place sample tubes to maintain the temperature conditions required for the reaction; while the reagent chamber is used to store reagent bottles at low temperatures to ensure the stability and activity of the reagents. The design of the reagent chamber is of great significance for maintaining the quality of the reagents, preventing contamination, and improving the accuracy of the test.

[0004] However, in the chemiluminescent immunoassay analyzer of the prior art, there are problems with the design of the reagent compartment door. The compartment door is usually opened and closed in parallel, that is, the compartment door is arranged in parallel with the compartment cover. Due to the low temperature in the reagent compartment, condensed water is easily condensed on the inside of the compartment door. In the process of opening and closing the compartment door, this condensed water may be thrown out and accidentally fall into the incubation test tube, thereby changing the concentration of the body fluid in the test tube. This unexpected contamination not only affects the detection accuracy of the chemiluminescent immunoassay analyzer, but may also mislead the clinical diagnosis results and increase medical risks.

[0005] In addition, the door design in the prior art may also cause unnecessary vibration or impact to the reagent bottle during the process of taking it, thereby affecting the stability and service life of the reagent. These problems not only reduce the detection efficiency of the chemiluminescent immunoassay analyzer, but also increase the maintenance cost and operation complexity.

[0006] Therefore, we urgently need an innovative solution to the problem of reagent compartment door design in the existing technology. This solution should effectively prevent condensed water from contaminating the incubation test tubes, while reducing the vibration and impact of the reagent bottles during the handling process, thereby ensuring the detection accuracy and stability of the chemiluminescent immunoassay analyzer. This improvement will not only improve the overall performance of the equipment, but also provide more reliable technical support for clinical medical diagnosis. Summary of the invention

[0007] The purpose of the present invention is to provide a reading device for a chemiluminescent immunoassay analyzer to solve the following technical problems: The chamber door is usually opened and closed in parallel, that is, the chamber door and the chamber cover are arranged in parallel. Since the temperature in the reagent chamber is relatively low, condensed water is easily condensed on the inside of the chamber door. In the process of opening and closing the chamber door, the condensed water may be thrown out and accidentally fall into the incubation test tube, thereby changing the concentration of the body fluid in the test tube. This unexpected contamination not only affects the detection accuracy of the chemiluminescent immunoassay analyzer, but may also mislead the clinical diagnosis results and increase medical risks.

[0008] The purpose of the present invention can be achieved through the following technical solutions:

[0009] A reading device for a chemiluminescent immunoassay analyzer, comprising a bin body, a lateral displacement assembly and a bin cover;

[0010] The bin cover comprises an upper cover and a lower cover, the interior of the lower cover is connected with an adsorption sponge 1, and the top of the upper cover is equipped with two symmetrically arranged fans;

[0011] An opening adapted to the lower cover is provided on one side of the top of the bin body, and a plurality of through slots communicating with the interior of the lower cover are provided at the bottom of the lower cover;

[0012] The lateral displacement assembly includes a mounting frame, an arc-shaped driving structure and a transverse plate. The arc-shaped driving structure is mounted on one side of the mounting frame, the transverse plate is arranged on the other side of the mounting frame and connected to the top of the upper cover, and the output end of the arc-shaped driving structure is connected to the transverse plate and is used to drive the transverse plate to perform an arc-shaped displacement on one side of the mounting frame.

[0013] As a further solution of the present invention: the arc-shaped driving structure includes a driving motor and two swing rods, the two swing rods are symmetrically arranged on one side of the horizontal plate and the top ends are rotatably connected to the side wall of the horizontal plate, the bottom end of the swing rod is fixedly connected to a rotating rod whose end is rotatably connected to the side wall of the mounting frame, and the output shaft of the driving motor is transmission-connected to the end of the rotating rod on one side.

[0014] As a further solution of the present invention: a limiting rod is provided on one side of the two swing arms that are away from each other, and one end of the limiting rod is connected to the side wall of the mounting frame.

[0015] As a further solution of the present invention: a connecting rod is fixedly connected to the bottom center of the horizontal plate, and one end of the connecting rod is connected to the top of the upper cover.

[0016] As a further solution of the present invention: a receiving frame is connected to the top of the bin body and near the opening, an adsorption sponge 2 is connected to the interior of the receiving frame, and a plurality of ventilation grooves connected to the interior of the receiving frame are provided on the side of the receiving frame away from the bin cover.

[0017] As a further solution of the present invention: a circular plate for connecting with the connecting rod is arranged at the top center of the upper cover, and both sides of the circular plate are connected to the top of the upper cover through brackets.

[0018] As a further solution of the present invention: each inner wall of the opening is provided with a first guide slope, each side surface of the lower cover is provided with a second guide slope, each of the second guide slopes is provided with a plurality of through grooves connected to the interior of the lower cover, and the wind directions of the two fans are arranged in opposite directions.

[0019] As a further solution of the present invention: the outer tops of the four guide inclined surfaces 2 are connected with sealing pads, and the ends of every two adjacent sealing pads are fixedly connected.

[0020] As a further solution of the present invention: a limiting frame is arranged inside the lower cover, the outer wall of the limiting frame is connected to the inner wall of the lower cover, and the inner wall is in contact with the side wall of the adsorption sponge.

[0021] As a further solution of the present invention: each inner wall of the limit frame is connected to a plurality of limit protrusions, and the limit frame is made of plastic material.

[0022] Beneficial effects of the present invention:

[0023] (1) In the present invention, a fan is started synchronously when the upper cover is opened to form a negative pressure. Combined with the through-slot design of the lower cover and the water absorption function of the adsorption sponge, the condensed water attached to the lower cover can be efficiently absorbed, thereby avoiding the risk of contamination of the incubation test tube by the condensed water, and significantly improving the detection accuracy and stability;

[0024] (2) The arc-shaped opening and closing lid design combined with the negative pressure water absorption mechanism in the present invention effectively reduces the throwing out of condensed water and the vibration impact of the reagent bottle during the opening and closing of the lid, reduces the contamination risk and loss rate of the reagent, and extends the service life of the reagent. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The present invention will be further described below in conjunction with the accompanying drawings.

[0026] Figure 1 It is a structural schematic diagram of the warehouse body of the present invention;

[0027] Figure 2 It is a schematic diagram of the structure of the bin cover of the present invention;

[0028] Figure 3 It is a schematic diagram of the structure of the upper cover and the lower cover of the present invention;

[0029] Figure 4 It is a schematic diagram of the structure of the limiting frame and the limiting protrusion of the present invention;

[0030] Figure 5 It is a schematic diagram of the structure of the lateral displacement assembly of the present invention;

[0031] Figure 6 It is a structural schematic diagram of the receiving frame and the adsorption sponge 2 of the present invention.

[0032] In the figure: 1. bin body; 2. lateral displacement assembly; 3. bin cover; 4. receiving frame; 5. guide slope 1; 6. opening; 201. drive motor; 202. mounting frame; 203. swing rod; 204. rotating rod; 205. limit rod; 206. horizontal plate; 207. connecting rod; 301. lower cover; 302. upper cover; 303. guide slope 2; 304. sealing pad; 305. adsorption sponge 1; 306. fan; 307. round plate; 308. bracket; 309. limit frame; 310. limit protrusion; 311. through groove; 401. adsorption sponge 2; 402. ventilation groove. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] Embodiment 1

[0035] See also Figure 1-6 As shown, a reading device for a chemiluminescent immunoassay analyzer in this embodiment includes a bin body 1, a lateral displacement assembly 2 and a bin cover 3;

[0036] The compartment cover 3 includes an upper cover 302 and a lower cover 301. The interior of the lower cover 301 is connected with an adsorption sponge 305. The top of the upper cover 302 is equipped with two symmetrically arranged fans 306.

[0037] An opening 6 adapted to the lower cover 301 is provided on one side of the top of the bin body 1, and a plurality of through slots 311 communicating with the interior of the lower cover 301 are provided on the bottom of the lower cover 301;

[0038] The lateral displacement assembly 2 includes a mounting frame 202, an arc-shaped driving structure and a transverse plate 206. The arc-shaped driving structure is installed on one side of the mounting frame 202, and the transverse plate 206 is arranged on the other side of the mounting frame 202 and connected to the top of the upper cover 302. The output end of the arc-shaped driving structure is connected to the transverse plate 206 and is used to drive the transverse plate 206 to perform an arc-shaped displacement on one side of the mounting frame 202.

[0039] Working principle of the present invention: In the chemiluminescent immunoassay analyzer, the chamber 1 is responsible for storing the reagent bottle at low temperature to maintain the stability and activity of the reagent. The top of the reagent chamber is designed with an opening 6 that matches the lower cover 301 to facilitate the storage and access of the reagent bottle. The lower cover 301 is equipped with an adsorption sponge 305 to absorb condensed water that may be generated in the chamber.

[0040] The bottom of the lower cover 301 is provided with a plurality of through grooves 311 connected to the inside, and when the reagent bottle needs to be stored and accessed, the lateral displacement assembly 2 starts working. The assembly is composed of a mounting frame 202, an arc driving structure and a cross plate 206, wherein the arc driving structure drives the cross plate 206 to move along an arc track on the mounting frame 202. The cross plate 206 is connected to the top of the upper cover 302, so that the upper cover 302 and the lower cover 301 are driven to move together, and the arc opening and closing of the reagent bin opening 6 is realized. When the upper cover 302 is opened, two symmetrical fans 306 installed on the top thereof start working, generating suction to form a negative pressure inside the bin cover 3. This negative pressure environment prompts the condensed water at the bottom of the lower cover 301 to be quickly sucked into the lower cover 301 through the through grooves 311, and is effectively absorbed by the adsorption sponge 305, thereby avoiding the risk of throwing out and contamination of the condensed water during the bin door opening and closing process.

[0041] Effects of the present invention: By synchronously starting the fan 306 to form negative pressure when the upper cover 302 is opened, combined with the design of the through slot 311 of the lower cover 301 and the water absorption function of the adsorption sponge 305, this solution can manage the condensed water attached to the lower cover 301. The condensed water is quickly sucked into the lower cover 301 and effectively absorbed, avoiding the risk of contamination of the incubation test tube by the condensed water, and improving the detection accuracy and stability. The arc-shaped opening and closing design of the compartment cover 3 combined with the negative pressure water absorption mechanism effectively avoids the throwing out of the condensed water and the vibration impact of the reagent bottle during the opening and closing of the compartment cover 3. This not only reduces the risk of reagent contamination, but also reduces the loss rate of the reagent and extends the service life of the reagent.

[0042] Embodiment 2

[0043] A reading device for a chemiluminescent immunoassay analyzer according to this embodiment, such as Figure 1-6As shown, the arc-shaped driving structure includes a driving motor 201 and two swinging rods 203, the two swinging rods 203 are symmetrically arranged on one side of the horizontal plate 206 and the top end is rotatably connected to the side wall of the horizontal plate 206, the bottom end of the swinging rod 203 is fixedly connected to a rotating rod 204 with one end rotatably connected to the side wall of the mounting frame 202, the output shaft of the driving motor 201 is transmission-connected to the end of the rotating rod 204 on one side, specifically, the driving motor 201 drives the rotating rod 204 to rotate, and then through the transmission action of the swinging rod 203, the horizontal plate 206 and the upper cover 302 and the lower cover 301 connected thereto move along the arc track, realizing the arc opening and closing of the reagent compartment opening. This design achieves the effect of making the opening and closing process of the compartment cover 3 smoother, reducing vibration and impact, and helping to protect the stability of the reagent bottle and the reagent.

[0044] Furthermore, a limit rod 205 is provided on the side of the two swing rods 203 that are away from each other, and one end of the limit rod 205 is connected to the side wall of the mounting frame 202. Specifically, the limit rod 205 limits the swing range of the swing rod 203, preventing mechanical failure or operational error caused by excessive swing amplitude. The effect of improving the stability and safety of the equipment is achieved, and the normal operation of the arc drive structure is ensured.

[0045] Furthermore, a connecting rod 207 is fixedly connected to the bottom center of the cross plate 206, and one end of the connecting rod 207 is connected to the top of the upper cover 302. Specifically, the connecting rod 207 directly transmits the movement of the cross plate 206 to the upper cover 302, which simplifies the transmission structure and improves the transmission efficiency.

[0046] Furthermore, a receiving frame 4 is connected to the top of the bin body 1 and near the opening 6, and an adsorption sponge 2 401 is connected to the interior of the receiving frame 4. A plurality of ventilation grooves 402 connected to the interior of the receiving frame 4 are provided on the side of the receiving frame 4 away from the bin cover 3. Specifically, when the bin cover 3 is opened, the adsorption bin cover 3 is driven by the arc driving structure to move in an arc to the top position of the receiving frame 4, so that the lower cover 301 contacts the top of the adsorption sponge 2 401, which can further absorb the residual condensed water or gas in the lower cover 301.

[0047] Embodiment 3

[0048] A reading device for a chemiluminescent immunoassay analyzer according to this embodiment, such as Figure 1-6 As shown, a circular plate 307 for connecting with the connecting rod 207 is provided at the top center of the upper cover 302, and both sides of the circular plate 307 are connected to the top of the upper cover 302 through brackets 308. Specifically, the circular plate 307 provides a stable support point for the connecting rod 207, and the bracket 308 enhances the connection strength between the circular plate 307 and the upper cover 302.

[0049] Furthermore, each inner wall of the opening 6 is provided with a guide slope 1 5, each side surface of the lower cover 301 is provided with a guide slope 2 303, and each guide slope 2 303 is provided with a plurality of through grooves 311 connected to the interior of the lower cover 301. The wind directions of the two fans 306 are set in opposite directions. Specifically, the guide slope 1 5 and the guide slope 2 303 cooperate with each other to guide the bin cover 3 to open and close smoothly, reducing friction and resistance. The purpose of setting the wind directions of the two fans 306 in opposite directions is that the fan 306 with the wind direction away from the lower cover 301 can form a negative pressure inside the bin cover 3 to absorb condensed water, and the fan 306 with the wind direction close to the lower cover 301 can blow air to the lower cover 301 when the bin cover 3 moves to the top of the receiving frame 4, so that the moisture inside the adsorption sponge 1 305 and the residual moisture in the lower cover 301 are transferred to the interior of the adsorption sponge 2 401 for collection.

[0050] Furthermore, the outer tops of the four guide slopes 303 are connected to sealing gaskets 304, and the ends of each two adjacent sealing gaskets 304 are fixedly connected. Specifically, the sealing gaskets 304 fit tightly against the edge of the opening 6 when the bin cover 3 is closed, effectively preventing the exchange of air and condensed water inside and outside the bin, thereby achieving the effect of improving the sealing of the bin body 1 and maintaining the stability of the environment inside the bin, thereby ensuring the quality and activity of the reagents.

[0051] Furthermore, a limiting frame 309 is provided inside the lower cover 301, the outer wall of the limiting frame 309 is connected to the inner wall of the lower cover 301, and the inner wall contacts the side wall of the adsorption sponge 305. Specifically, the limiting frame 309 and the limiting protrusion 310 jointly limit the position and shape of the adsorption sponge 305 to prevent it from shifting or deforming during the water absorption process. The effect of maintaining the stability of the adsorption sponge and improving the water absorption efficiency is achieved, ensuring the effective absorption of condensed water.

[0052] Furthermore, each inner wall of the limit frame 309 is connected with a plurality of limit bumps 310, and the limit frame 309 is made of plastic material. Specifically, the plastic material has good processability and corrosion resistance, and can meet the requirements of the equipment for material properties, thereby achieving the effect of reducing costs, improving production efficiency and equipment durability.

[0053] The above is a detailed description of an embodiment of the present invention, but the content is only a preferred embodiment of the present invention and cannot be considered to limit the scope of implementation of the present invention. All equivalent changes and improvements made within the scope of the present invention should still fall within the scope of the patent coverage of the present invention.

Claims

1. A reading device for a chemiluminescent immunoassay analyzer, characterized in that: include: A bin body (1), a lateral displacement assembly (2) and a bin cover (3); The bin cover (3) comprises an upper cover (302) and a lower cover (301), the interior of the lower cover (301) is connected with an adsorption sponge (305), and the top of the upper cover (302) is equipped with two symmetrically arranged fans (306); An opening (6) adapted to the lower cover (301) is provided on one side of the top of the bin body (1), and a plurality of through slots (311) communicating with the interior of the lower cover (301) are provided on the bottom of the lower cover (301); The lateral displacement assembly (2) comprises a mounting frame (202), an arc-shaped driving structure and a transverse plate (206); the arc-shaped driving structure is mounted on one side of the mounting frame (202); the transverse plate (206) is arranged on the other side of the mounting frame (202) and is connected to the top of the upper cover (302); the output end of the arc-shaped driving structure is connected to the transverse plate (206) and is used to drive the transverse plate (206) to perform arc-shaped displacement on one side of the mounting frame (202).

2. A reading device for a chemiluminescent immunoassay analyzer according to claim 1, characterized in that: The arc-shaped driving structure comprises a driving motor (201) and two swinging rods (203), wherein the two swinging rods (203) are symmetrically arranged on one side of a horizontal plate (206) and the top ends are rotatably connected to the side wall of the horizontal plate (206), the bottom ends of the swinging rods (203) are fixedly connected to a rotating rod (204) having one end rotatably connected to the side wall of a mounting frame (202), and the output shaft of the driving motor (201) is drivingly connected to the end of the rotating rod (204) on one side.

3. A reading device for a chemiluminescent immunoassay analyzer according to claim 2, characterized in that: A limiting rod (205) is provided on the side of the two swing rods (203) that is away from each other, and one end of the limiting rod (205) is connected to the side wall of the mounting frame (202).

4. A reading device for a chemiluminescent immunoassay analyzer according to claim 3, characterized in that: A connecting rod (207) is fixedly connected to the center of the bottom of the transverse plate (206), and one end of the connecting rod (207) is connected to the top of the upper cover (302).

5. A reading device for a chemiluminescent immunoassay analyzer according to claim 3, characterized in that: A receiving frame (4) is connected to the top of the bin body (1) and near the opening (6), and an adsorption sponge 2 (401) is connected to the interior of the receiving frame (4). A plurality of ventilation slots (402) communicating with the interior of the receiving frame (4) are provided on a side of the receiving frame (4) away from the bin cover (3).

6. A reading device for a chemiluminescent immunoassay analyzer according to claim 4, characterized in that: A circular plate (307) for connecting with the connecting rod (207) is arranged at the top center of the upper cover (302), and both sides of the circular plate (307) are connected to the top of the upper cover (302) through brackets (308).

7. A reading device for a chemiluminescent immunoassay analyzer according to claim 5, characterized in that: Each inner wall of the opening (6) is provided with a first guiding slope (5), each side surface of the lower cover (301) is provided with a second guiding slope (303), each of the second guiding slopes (303) is provided with a plurality of through slots (311) communicating with the interior of the lower cover (301), and the wind directions of the two fans (306) are arranged in opposite directions.

8. A reading device for a chemiluminescent immunoassay analyzer according to claim 7, characterized in that: The outer tops of the four second guiding inclined surfaces (303) are all connected with sealing pads (304), and the ends of each two adjacent sealing pads (304) are fixedly connected.

9. A reading device for a chemiluminescent immunoassay analyzer according to claim 7, characterized in that: A limiting frame (309) is provided inside the lower cover (301), the outer wall of the limiting frame (309) is connected to the inner wall of the lower cover (301), and the inner wall is in contact with the side wall of the adsorption sponge (305).

10. A reading device for a chemiluminescent immunoassay analyzer according to claim 9, characterized in that: Each inner wall of the limiting frame (309) is connected to a plurality of limiting protrusions (310), and the limiting frame (309) is made of plastic material.

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