Edible gel composition for adsorbing alcohol as well as preparation method and application thereof

Abstract

The invention relates to the technical field of hangover alleviating products, in particular to an edible gel composition for adsorbing alcohol as well as a preparation method and application of the edible gel composition. The edible gel composition for adsorbing alcohol comprises the following raw materials: a carboxymethyl cellulose raw material, an alginic acid raw material and a calcium source, and the mass relationship of the components in the raw materials meets: W1 = m < 2 > / (m1 + m < 2 >) * 100%, and W1 is greater than or equal to 12% and less than or equal to 35%; f = m4 / m3, and 0.1 < = f < = 1.2; wherein m1 is the mass of the carboxymethyl cellulose raw material, m2 is the mass of the alginic acid raw material, m3 is the mass of carboxyl in the alginic acid raw material, and m4 is the mass of Ca < 2 + > in the calcium source. The edible gel composition has a remarkable adsorption characteristic on alcohol, and can quickly adsorb alcohol in the stomach, delay the speed and time of the alcohol entering blood, relieve the metabolic burden of the alcohol on the body and further relieve the damage of the alcohol to the nervous system.

Description

Technical Field

[0001] The invention relates to the technical field of hangover sobering products, and in particular to an edible gel composition for absorbing alcohol, a preparation method thereof and an application thereof. Background Art

[0002] Studies have shown that about 90% of the alcohol consumed by the human body is metabolized in the liver, and excessive drinking can directly damage liver cells and cause liver enzyme leakage, which in turn causes liver damage. Long-term excessive drinking can induce a series of liver diseases, such as alcoholic hepatitis, fibrosis, cirrhosis and even hepatocellular carcinoma, which have become the main threat to liver health after other factors. Therefore, it is necessary to sober up after drinking to reduce the damage of alcohol to the human body.

[0003] Although a large number of alcohol sobering and liver protection products, such as alcohol sobering drugs, herbal preparations and health products, have appeared on the market to cope with and solve the health problems caused by excessive drinking. Although these drugs have a certain alcohol sobering effect, they can only work after alcohol enters the blood and passes through the liver, which will inevitably cause metabolic burdens on the liver and kidneys, causing varying degrees of damage. Therefore, preventing alcohol from entering the blood becomes the key to solving the above problems.

[0004] In view of this, the present invention is proposed. Summary of the invention

[0005] The purpose of the present invention is to provide an edible gel composition for absorbing alcohol, a preparation method thereof and an application thereof. The embodiment of the present invention provides an edible gel composition, which has a significant adsorption property for alcohol, can quickly absorb alcohol in the stomach, delay the speed and time of alcohol entering the blood, reduce the metabolic burden of alcohol on the body, and further reduce the damage caused by alcohol to the nervous system.

[0006] The present invention is achieved in that:

[0007] In a first aspect, the present invention provides an edible gel composition for absorbing alcohol, wherein the raw materials thereof include a carboxymethyl cellulose raw material, an alginate raw material and a calcium source, and the mass relationship of the components in the raw materials satisfies:

[0008] W1=m2 / (m1+m2)×100%, and 12%≤W1≤35%;

[0009] f=m4 / m3, and 0.1≤f≤1.2;

[0010] Among them, m1 is the mass of carboxymethyl cellulose raw materials, m2 is the mass of alginate raw materials, m3 is the mass of carboxyl groups in alginate raw materials, and m4 is the Ca in calcium source. 2+ quality.

[0011] In an optional embodiment, the adsorption rate of the edible gel composition on 43% liquor is ≥700%.

[0012] In an optional embodiment, when the concentration of the carboxymethyl cellulose raw material in the solution is 2%, the viscosity is ≥3000 mPa·S.

[0013] In an optional embodiment, the carboxymethyl cellulose raw material includes carboxymethyl cellulose or a salt thereof;

[0014] Preferably, the carboxymethyl cellulose raw material includes any one of sodium carboxymethyl cellulose, potassium carboxymethyl cellulose and ammonium carboxymethyl cellulose.

[0015] In an optional embodiment, when the concentration of the alginate raw material in the solution is 2%, the viscosity is ≥3000 mPa·S;

[0016] Preferably, the alginic acid raw material includes alginic acid or its salt;

[0017] More preferably, the salt of alginic acid includes any one of sodium alginate, potassium alginate and ammonium alginate.

[0018] In an optional embodiment, the calcium source is a calcium source with low solubility;

[0019] Preferably, the calcium source includes at least one of calcium carbonate, calcium chloride, calcium citrate, calcium lactate, calcium gluconate, calcium acetate and calcium phosphate; more preferably, it is one of calcium lactate, calcium carbonate and calcium phosphate.

[0020] In a second aspect, the present invention provides a method for preparing an edible gel composition for absorbing alcohol as described in the aforementioned embodiment, wherein a carboxymethyl cellulose raw material, an alginate raw material and a calcium source are mixed according to a certain proportion.

[0021] In an optional embodiment, the method comprises: mixing a carboxymethyl cellulose raw material, an alginic acid raw material and water, drying the mixture at 70-150° C. after uniform mixing, and then crushing the mixture to obtain material A;

[0022] Next, the material A and the calcium source are mixed;

[0023] Preferably, the concentration of the carboxymethyl cellulose raw material and the alginic acid raw material in the water is 4-15%.

[0024] The particle size of material A is 0.1 mm to 2 mm, more preferably 0.3 mm to 2 mm, and more preferably 0.3 mm to 1 mm.

[0025] In a third aspect, the present invention provides a use of the edible gel composition for absorbing alcohol as described in the aforementioned embodiment in preparing a product for absorbing alcohol;

[0026] Preferably, the product is a hangover-relieving health product or hangover-relieving medicine.

[0027] The present invention has the following beneficial effects: the embodiment of the present invention provides an edible gel composition, which has significant adsorption characteristics for alcohol, and then after the user takes the edible gel composition, it can quickly adsorb alcohol after reaching the stomach. At the same time, the edible gel composition has a certain strength to withstand the grinding force generated by gastric peristalsis, prolonging the residence time of the alcohol-containing edible gel composition in the stomach, thereby delaying the speed and time of alcohol entering the blood, reducing the metabolic burden of alcohol on the body, and further reducing the damage caused by alcohol to the nervous system. The preparation process of the edible gel composition of the present invention is simple and convenient for commercial-scale production. DETAILED DESCRIPTION

[0028] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be described clearly and completely below. If the specific conditions are not specified in the embodiments, they are carried out according to conventional conditions or conditions recommended by the manufacturer. If the manufacturer of the reagents or instruments used is not specified, they are all conventional products that can be purchased commercially.

[0029] In a first aspect, the present invention provides an edible gel composition for absorbing alcohol, wherein the raw materials thereof include a carboxymethyl cellulose raw material, an alginate raw material and a calcium source, and the mass relationship of the components in the raw materials satisfies:

[0030] W1=m2 / (m1+m2)×100%, and 12%≤W1≤35%;

[0031] f = m4 / m3, and 0.1≤f≤1.2; wherein m1 is the mass of the carboxymethyl cellulose raw material, m2 is the mass of the alginate raw material, m3 is the mass of the carboxyl group in the alginate raw material, and m4 is the Ca in the calcium source. 2+ quality.

[0032] The edible gel composition has a significant adsorption property for alcohol, and after the user takes the edible gel composition, it can quickly absorb alcohol after reaching the stomach. At the same time, the edible gel composition has a certain strength to withstand the grinding force generated by the peristalsis of the stomach, prolonging the residence time of the alcohol-containing edible gel composition in the stomach, thereby delaying the speed and time of alcohol entering the blood, reducing the metabolic burden of alcohol on the body, and further reducing the damage caused by alcohol to the nervous system.

[0033] Therefore, the edible gel composition provided by the embodiment of the present invention can be used to prepare products that absorb alcohol, such as but not limited to alcohol sobering health products and alcohol sobering medicines. Specifically, the adsorption rate of the edible gel composition on 43% liquor is ≥700%.

[0034] Specifically, W1 may be any value between 12-35%, such as 12%, 15%, 17%, 20%, 25%, 30%, and 35%.

[0035] f is any value between 0.1 and 1.2, such as 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1 and 1.2.

[0036] Specifically, when the concentration of the carboxymethyl cellulose raw material in the solution is 2%, the viscosity is ≥3000 mPa·S. The carboxymethyl cellulose raw material includes carboxymethyl cellulose or its salt, for example, the carboxymethyl cellulose raw material includes but is not limited to any one of sodium carboxymethyl cellulose, potassium carboxymethyl cellulose and ammonium carboxymethyl cellulose.

[0037] When the concentration of the alginic acid raw material in the solution is 2%, the viscosity is ≥3000 mPa·S. The alginic acid raw material includes alginic acid or its salt; for example, the alginate includes but is not limited to any one of sodium alginate, potassium alginate and ammonium alginate.

[0038] It should be noted that the above viscosity refers to the properties of the alginate-based raw material or the carboxymethyl cellulose-based raw material itself.

[0039] The embodiment of the present invention further limits the viscosity of the alginate raw material or the carboxymethyl cellulose raw material itself, so that the formed edible gel composition has a better adsorption effect on alcohol.

[0040] The calcium source is a calcium source with low solubility; for example, the calcium source includes but is not limited to at least one of calcium carbonate, calcium chloride, calcium citrate, calcium lactate, calcium gluconate, calcium acetate and calcium phosphate; more preferably, it is one of calcium lactate, calcium carbonate and calcium phosphate.

[0041] In a second aspect, the present invention provides a method for preparing an edible gel composition for absorbing alcohol as described in the aforementioned embodiment, wherein a carboxymethyl cellulose raw material, an alginate raw material and a calcium source are mixed according to a certain proportion.

[0042] Specifically, carboxymethyl cellulose raw materials, alginic acid raw materials and water are mixed, dried at 70-150°C after mixing evenly, and then crushed to obtain material A; the concentration of the carboxymethyl cellulose raw materials and the alginic acid raw materials in the water is 4-15%, and the concentration refers to the mass content of the carboxymethyl cellulose raw materials and the alginic acid raw materials in the water. The particle size of the above material A is 0.1mm-2mm, more preferably 0.3mm-2mm, and more preferably 0.3mm-1mm.

[0043] Alternatively, the carboxymethyl cellulose raw material, the alginic acid raw material, the calcium source and water may be directly mixed.

[0044] The features and performance of the present invention are further described in detail below in conjunction with the embodiments.

[0045] Example 1

[0046] An embodiment of the present invention provides a method for preparing an edible gel composition, comprising:

[0047] 3.0g sodium alginate, 20g sodium carboxymethyl cellulose (W1=13%), and 500mL water are placed in a dough mixer and mixed evenly to form a uniform suspension. The suspension is transferred to a metal tray, and the thickness of the suspension in the metal tray is controlled to be less than 1cm, and then the metal tray is placed at 70°C and dried for 24h to obtain solid material A. The solid material A is placed in a grinder and crushed, and passed through 16 mesh and 150 mesh sieves, and sieved to obtain granular material A with a particle size of 0.1-1mm, which is packaged for later use.

[0048] Calcium lactate is mixed with material A, wherein the mass of calcium lactate and the mass of sodium alginate in material A satisfy f=0.3.

[0049] When the concentration of the carboxymethyl cellulose raw material in the solution is 2%, the viscosity is 6000 mPa·s.

[0050] When the concentration of alginate raw materials in the solution is 2%, the viscosity is 4000 mPa·s.

[0051] Example 2

[0052] An embodiment of the present invention provides a method for preparing an edible gel composition, comprising:

[0053] 5.0g sodium alginate, 20g sodium carboxymethyl cellulose (W1=20%), and 500mL water are placed in a dough mixer and mixed evenly to form a uniform suspension. The suspension is transferred to a metal tray, and the thickness of the suspension in the metal tray is controlled to be less than 1cm. The metal tray is then placed at 70°C and dried for 24h to obtain solid material A. The solid material A is placed in a grinder and crushed, and passed through 10-mesh and 120-mesh sieves to obtain granular material A with a particle size of 0.1-1.7mm, which is packaged for later use.

[0054] Calcium citrate is mixed with material A, wherein the mass of calcium citrate and the mass of sodium alginate in material A satisfy f=0.1.

[0055] When the concentration of the carboxymethyl cellulose raw material in the solution is 2%, the viscosity is 4000 mPa·s.

[0056] When the concentration of alginic acid raw materials in the solution is 2%, the viscosity is 5000 mPa·s.

[0057] Example 3

[0058] This embodiment provides a method for preparing an edible gel composition. The preparation method is based on the preparation method provided in Example 2, with the only difference being that f is 0.2. Other operating conditions, raw material selection, and dosage are the same as those in Example 2.

[0059] Example 4

[0060] This embodiment provides a method for preparing an edible gel composition. The preparation method is based on the preparation method provided in Example 2, with the only difference being that f is 0.8 and the calcium source is calcium lactate. Other operating conditions, raw material selection, and dosage are the same as those in Example 2.

[0061] Example 5

[0062] An embodiment of the present invention provides a method for preparing an edible gel composition, comprising:

[0063] 7.5g sodium alginate, 15.0g sodium carboxymethyl cellulose (W1=33.3%), and 500mL water are placed in a dough mixer and mixed evenly to form a uniform suspension. The suspension is transferred to a metal tray, and the thickness of the suspension in the metal tray is controlled to be less than 1cm. The metal tray is then placed at 70°C and dried for 24h to obtain solid material A. The solid material A is placed in a grinder and crushed, and passed through 18 mesh and 50 mesh sieves, and sieved to obtain granular material A with a particle size of 0.27-0.88mm, which is packaged for later use.

[0064] Calcium citrate is mixed with solid material A, wherein the mass of calcium citrate and the mass of sodium alginate in material A satisfy f=0.1.

[0065] When the concentration of the carboxymethyl cellulose raw material in the solution is 2%, the viscosity is 12000 mPa·s.

[0066] When the concentration of alginic acid raw materials in the solution is 2%, the viscosity is 5500 mPa·s.

[0067] Example 6

[0068] This embodiment provides a method for preparing an edible gel composition. The preparation method is based on the preparation method provided in Example 5, with the only difference being that f is 0.2. Other operating conditions, raw material selection, and dosage are the same as those in Example 5.

[0069] Example 7

[0070] An embodiment of the present invention provides a method for preparing an edible gel composition, comprising:

[0071] 5.0g sodium alginate, 20.0g sodium carboxymethyl cellulose (W1=20%), 3.8g calcium carbonate, 500mL water are placed in a dough mixer and mixed evenly to form a uniform suspension. The suspension is transferred to a metal tray, the thickness of the suspension in the metal tray is controlled to be less than 1cm, and then the metal tray is placed at 70°C for drying for 24h to obtain material A. The solid material A is placed in a grinder and crushed, passed through 18 mesh and 150 mesh sieves, and sieved to obtain a granular material with a particle size of 0.1-0.88mm, which is packaged for later use.

[0072] Calcium gluconate is mixed with solid material A, wherein the mass of calcium gluconate and the mass of sodium alginate in material A satisfy f=1.2.

[0073] When the concentration of the carboxymethyl cellulose raw material in the solution is 2%, the viscosity is 6000 mPa·s.

[0074] When the concentration of alginic acid raw materials in the solution is 2%, the viscosity is 8000 mPa·s.

[0075] Comparative Example 1

[0076] This comparative example provides a method for preparing an edible gel composition. The preparation method is based on the preparation method provided in Example 1, with the only difference being that f is 1.5, and other operating conditions, raw material selection, and dosage are the same as those in Example 1.

[0077] Comparative Example 2

[0078] This comparative example provides a method for preparing an edible gel composition. The preparation method is based on the preparation method provided in Example 1, with the only difference being that W1=66.7%. Other operating conditions, raw material selection and dosage are the same as those in Example 1.

[0079] Comparative Example 3

[0080] This comparative example provides a method for preparing an edible gel composition. The preparation method is based on the preparation method provided in Example 1, with the only difference being that W1=66.7% and f=1.6. Other operating conditions, raw material selection and dosage are the same as those in Example 1.

[0081] Comparative Example 4

[0082] This comparative example provides a method for preparing an edible gel composition. The preparation method is similar to the preparation method provided in Example 1, except that only 23 g of sodium alginate is used, and the ratio of sodium alginate to calcium lactate is still 0.3.

[0083] Comparative Example 5

[0084] The comparative example provides a commercially available jelly-type hangover-relieving gel, the main components of which are plant premix powder (psyllium husk powder, gluten powder, konjac powder, acetylated distarch phosphate, white kidney bean extract), konjac powder, carrageenan, xanthan gum, citric acid, turmeric, pectin, starch, white kidney bean powder (Phaseolus vulgaris), chia seeds, and yeast extract (glutathione).

[0085] Experimental Example 1

[0086] The highest alcohol content of liquor is 68%. Normally, the gastric acid capacity of an adult on an empty stomach is 50-100mL. For the convenience of calculation, the average value is 75mL. If an adult drinks up to 100mL of 68% liquor at a time, it can be calculated that the concentration of alcohol after being diluted by gastric acid in the stomach is 38.9%. To facilitate the experiment, 43% of commercially available liquor was used for the experiment. According to Appendix H of GB / T 22875-2018, the physiological saline was replaced with 43% liquor, and the absorption of liquor by Examples 1-7 and Comparative Examples 1-6 was measured respectively. The absorption amount X*100 was obtained, and the adsorption rate (%) of alcohol was obtained.

[0087] The results are shown in Table 1.

[0088] Table 1 Alcohol adsorption rate results

[0089]

[0090]

[0091] According to Table 1, if W1 or f or the raw material selection specified in the embodiment of the present invention is changed, the adsorption efficiency of alcohol by the formed edible gel composition will be greatly reduced, which further shows that only the edible gel composition provided by the embodiment of the present invention can effectively and efficiently adsorb alcohol, indicating that it has unexpected technical effects.

[0092] Experimental Example 2

[0093] 30 volunteers were recruited to test the real effects of the gel compositions prepared by different methods. The volunteers drank 2.4 g of the edible gel composition of Example 4 and the jelly-type hangover gel of Comparative Example 5 immediately after drinking according to their usual drinking habits. Compared with the previous state, the volunteers evaluated the anti-alcohol effect after taking the hydrogel and determined it as "useless", "normal", "good" or "perfect".

[0094] The results are shown in Tables 2 and 3.

[0095] Table 2 Test results of the edible gel composition of Example 4

[0096] Effect Type Relieve hangover Improve your drinking capacity Speed ​​up awakening Overall satisfaction useless 0 0 0 0 generally 0 1 0 1 good 23 6 12 10 Perfect 7 23 18 19

[0097] Table 3 Test results of the jelly type hangover gel of comparative example 5

[0098]

[0099]

[0100] It can be seen from Table 2 and Table 3 that the edible gel composition provided by the embodiment of the present invention can effectively improve the state after drinking.

[0101] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. An edible gel composition for absorbing alcohol, characterized in that: The raw materials include carboxymethyl cellulose raw materials, alginic acid raw materials and calcium sources, and the mass relationship of each component in the raw materials satisfies: W1=m2 / (m1+m2)×100%, and 12%≤W1≤35%; f=m4 / m3, and 0.1≤f≤1.2; Among them, m1 is the mass of carboxymethyl cellulose raw materials, m2 is the mass of alginate raw materials, m3 is the mass of carboxyl groups in alginate raw materials, and m4 is the Ca in calcium source. 2+ quality.

2. The edible gel composition for absorbing alcohol according to claim 1, characterized in that: The adsorption rate of the edible gel composition on 43% liquor is ≥700%.

3. The edible gel composition for absorbing alcohol according to claim 1, characterized in that: When the concentration of the carboxymethyl cellulose raw material in the solution is 2%, the viscosity is ≥3000 mPa·S.

4. The edible gel composition for absorbing alcohol according to claim 1, characterized in that: The carboxymethyl cellulose raw material includes carboxymethyl cellulose or its salt, Preferably, the carboxymethyl cellulose raw material includes any one of sodium carboxymethyl cellulose, potassium carboxymethyl cellulose and ammonium carboxymethyl cellulose.

5. The edible gel composition for absorbing alcohol according to claim 1, characterized in that: When the concentration of the alginate raw material in the solution is 2%, the viscosity is ≥3000 mPa·S; Preferably, the alginic acid raw material includes alginic acid or its salt; Further preferably, the salt of alginic acid includes any one of sodium alginate, potassium alginate and ammonium alginate.

6. The edible gel composition for absorbing alcohol according to claim 1, characterized in that: The calcium source is a calcium source with low solubility; Preferably, the calcium source includes at least one of calcium carbonate, calcium chloride, calcium citrate, calcium lactate, calcium gluconate, calcium acetate and calcium phosphate; more preferably, it is one of calcium lactate, calcium carbonate and calcium phosphate.

7. A method for preparing an edible gel composition for absorbing alcohol according to claim 1, characterized in that: The carboxymethyl cellulose raw material, the alginic acid raw material and the calcium source are mixed according to a certain proportion.

8. The preparation method according to claim 7, characterized in that: include: Mix carboxymethyl cellulose raw materials, alginic acid raw materials and water, mix well, dry at 70-150°C, and then grind to obtain material A; Next, the material A and the calcium source are mixed; Preferably, the concentration of the carboxymethyl cellulose raw material and the alginic acid raw material in the water is 4-15%.

9. The preparation method according to claim 8, characterized in that: The particle size of the material A is 0.1 mm to 2 mm, more preferably 0.3 mm to 2 mm, and more preferably 0.3 mm to 1 mm.

10. Use of the edible gel composition for absorbing alcohol according to claim 1 in preparing products for absorbing alcohol; Preferably, the product is a hangover-relieving health product or hangover-relieving medicine.

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