Tumor Therapeutic Fields System

Abstract

The present application provides a tumor electric field therapy system, comprising an electric field generator and several pairs of electrode sheets electrically connected to the electric field generator. The electrode sheets include an electrode array, which comprises a main trunk and several branches extending radially from the main trunk. The main trunk is provided with several electrode units and a connection portion connecting two adjacent electrode units. Each branch is also provided with an electrode unit and a connection portion connecting the electrode unit to the main trunk. Each electrode unit on a branch is connected to the main trunk only through a corresponding connection portion. The electrode array also has an AC signal trace, several ground traces, and several signal traces. The present application's tumor electric field therapy system can reduce the number of conductive traces on the electrode sheet, simplifying the layout of the conductive traces.

Description

Technical Field

[0001] The present application relates to the field of medical device technology, and in particular to a tumor electric field therapy system. Background Art

[0002] Tumor electric field therapy is a tumor treatment method that uses a special electric field generator to generate a low-intensity, medium-high frequency, alternating electric field to interfere with the mitotic process of tumor cells. Studies have shown that electric field therapy is effective in treating diseases such as glioblastoma, non-small cell lung cancer, and malignant pleural mesothelioma. The electric field applied by this treatment method can affect the aggregation of microtubules, prevent spindle formation, inhibit the mitotic process, and induce apoptosis of cancer cells. The tumor electric field therapy system mainly includes an electric field generator, an adapter, and multiple pairs of electrodes. The electric field generator generates an alternating electrical signal and transmits the alternating electrical signal to the electrodes through the adapter. The electrodes are applied in pairs to the patient's body surface on opposite sides of the tumor area, and an alternating current signal is applied between each pair of electrodes to non-invasively apply the tumor treatment electric field to the tumor area.

[0003] During electric field therapy, the electrode sheet will accumulate heat at the application site, and the temperature will rise accordingly. Therefore, it is necessary to monitor the temperature at the application site. When the temperature is too high, the electric field strength needs to be adjusted in time to avoid the risk of burns on the patient's skin due to excessive temperature. The electrode sheet is usually provided with multiple electrode units. Even if the same AC signal is applied to each electrode unit, the heat generated by each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the electrode sheet will not be completely consistent. It is possible that the temperature of a certain electrode unit exceeds the temperature threshold while the temperature of other electrode units is normal. Therefore, it is necessary to provide a temperature sensor on each electrode unit to detect the temperature of each electrode unit in order to effectively avoid the risk of burns caused by excessive temperature of a single electrode unit. The existing electrode sheet is provided with a conductive trace for transmitting the temperature detection signal for each electrode unit. When the number of electrode units is large, the number of conductive traces on the electrode sheet also increases accordingly, resulting in a more complicated wiring scheme and affecting the flexibility of the electrode sheet, resulting in poor application.

[0004] Therefore, it is necessary to provide an improved tumor electric field therapy system and electrode sheet to overcome the problems existing in the prior art. Summary of the Invention

[0005] The present application provides a tumor electric field therapy system, which can simplify the layout of conductive traces on an electrode sheet.

[0006] Specifically, the present application is implemented through the following technical solutions: a tumor electric field treatment system, which includes an electric field generator and several pairs of electrode sheets electrically connected to the electric field generator, the electrode sheets including an electrode array, the electrode array including a trunk and several branches extending radially from the trunk to the surrounding areas, the trunk is provided with several electrode units and a connection portion connecting two adjacent electrode units; the branch is also provided with an electrode unit and a connection portion connecting the electrode unit to the trunk, each of the electrode units located on the branch is connected to the trunk only through a corresponding connection portion; the electrode array also has an AC signal trace for transmitting alternating current signals to each electrode unit, several ground traces for short-circuiting the ground ends of the corresponding electrode units to ground, and several signal traces for connecting the signal ends of the corresponding electrode units in parallel and cooperating with the ground traces to transmit the temperature detection signals of the corresponding electrode units in time-sharing.

[0007] According to one embodiment of the present invention, the electrode unit includes a plurality of central electrode units provided on the trunk and a plurality of peripheral electrode units provided on the branches, and each of the peripheral electrode units is connected only to the closest central electrode unit via the corresponding connecting portion.

[0008] According to one embodiment of the present invention, the electrode units are divided into multiple rows and columns in terms of circuit connection, the ground ends of the electrode units in each row are connected to the same ground trace, the signal ends of the electrode units in each column are connected to the same signal trace, and the AC signal trace connects each electrode unit.

[0009] According to one embodiment of the present invention, the tumor electric field therapy system further includes an AC line, a plurality of grounding switches, and a plurality of detection channels, wherein the AC line is connected to the AC signal trace, the grounding trace is connected to the grounding switches in a one-to-one correspondence, and the signal trace is connected to the detection channels in a one-to-one correspondence; the detection channels are all turned on when collecting the temperature detection signals of the electrode units, and the grounding switches are closed individually and sequentially when collecting the temperature detection signals of the electrode units.

[0010] According to one embodiment of the present invention, each electrode unit is provided with a temperature sensor, and the temperature sensor is provided with a ground terminal and a signal terminal. The ground terminal of the temperature sensor is the ground terminal of the corresponding electrode unit, and the signal terminal of the temperature sensor is the signal terminal of the corresponding electrode unit.

[0011] According to one embodiment of the present invention, there are thirteen electrode units and four ground traces, wherein each of the three ground traces is respectively connected to the ground ends of the three electrode units, and the other ground trace is connected to the ground ends of the remaining four electrode units; there are four signal traces, wherein each of the three signal traces is respectively connected to the signal ends of the four electrode units, and the other signal trace is only connected to the signal end of the remaining one electrode unit.

[0012] According to one embodiment of the present invention, the thirteen electrode units are spatially arranged into five rows and five columns, the first row and the fifth row each have two electrode units and are respectively located on the second column and the fourth column, the middle three rows each have three electrode units and are respectively located on the first column, the third column and the fifth column; in terms of circuit connection, the ground ends of the two electrode units in the first row and any electrode unit in the fifth row are each connected to one ground trace; the ground ends of the three electrode units in the second row are each connected to one ground trace; the ground ends of the three electrode units in the third row are each connected to one ground trace; the ground ends of the three electrode units in the fourth row and the remaining electrode unit in the fifth row are each connected to one ground trace.

[0013] According to one embodiment of the present invention, in terms of circuit connection, the signal end of any one of the electrode units located in the fifth row is connected to one of the signal traces; the signal ends of the three electrode units located in the third column and the remaining one of the electrode units located in the fifth row are respectively connected to one of the signal traces; the signal ends of the three electrode units located in the first column and any one of the electrode units in the first row are respectively connected to one of the signal traces; the signal ends of the three electrode units located in the fifth column and the remaining one of the electrode units located in the first row are respectively connected to one of the signal traces.

[0014] According to one embodiment of the present invention, the electrode array is provided with a flexible substrate, and most of the ground traces and the signal traces are arranged on the back of the substrate; each of the electrode units is provided with a conductive plate located on the front of the substrate, and the AC signal traces are arranged on the front of the substrate and connected to each of the conductive plates.

[0015] According to one embodiment of the present invention, part of the ground traces and / or part of the signal traces pass through the substrate to the front side of the substrate for jumpering, and then pass back to the back side of the substrate for further routing.

[0016] According to one embodiment of the present invention, the electrode array is provided with a wiring portion, and a plurality of gold fingers are respectively provided on the front and back sides of the wiring portion. The end of each ground trace passes through the wiring portion and is connected to the corresponding gold finger located on the front side of the wiring portion, and the end of each signal trace is connected to the corresponding gold finger located on the back side of the wiring portion.

[0017] According to one embodiment of the present invention, the electrode unit is provided with a dielectric element electrically connected to the conductive disk.

[0018] According to one embodiment of the present invention, the electrode unit is provided with a diode connected in series between the ground terminal of the temperature sensor and the ground trace.

[0019] The tumor electric field therapy system of the present application adopts a temperature measurement method of obtaining the temperature value of each temperature sensor in batches, which can reduce the number of conductive traces on the electrode sheet and simplify the layout scheme of the conductive traces on the electrode sheet.

[0020] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 1 is a framework diagram of a tumor treating field system according to one embodiment of the present application;

[0022] Figure 2 A three-dimensional diagram of an electrode sheet of the tumor electric field treatment system according to the present application;

[0023] Figure 3 for Figure 2 A partially exploded perspective view of the electrode sheet shown;

[0024] Figure 4 for Figure 3 A plan view of the electrode array of the electrode sheet shown;

[0025] Figure 5 for Figure 4 An exploded perspective view of the electrode array shown;

[0026] Figure 6 for Figure 5 The wiring diagram of the front side of the substrate of the electrode array shown;

[0027] Figure 7 for Figure 5 a wiring diagram of the ground traces on the back side of the substrate of the electrode array shown;

[0028] Figure 8 for Figure 5 A wiring diagram of the signal traces on the back side of the substrate of the electrode array shown;

[0029] Figure 9 This is a schematic diagram of the circuit connection between an electrode and an adapter in a tumor electric field therapy system.

[0030] Description of reference numerals:

[0031] Tumor electric field therapy system 100, electric field generator 10, adapter 20, controller 21, analog-to-digital conversion module 22, communication unit 23, voltage divider resistor 24, ground switch 25, power module 26, AC line 27, electrode sheet 30, electrode array 31, electrode unit 310, central electrode unit 310A, peripheral electrode unit 310B, connector 311, connection portion 312, gold finger 3121, substrate 313, main body 3131, connecting bar 3132, dielectric element 314, opening 3141, temperature sensor 315, ground terminal 3151, signal terminal 3152, support plate 3153 16. Conductive pad 3171, ground pad 3172, signal pad 3173, conductive trace 318, AC signal trace 318A, ground trace 318B, first ground trace 318B-1, second ground trace 318B-2, third ground trace 318B-3, fourth ground trace 318B-4, signal trace 318C, first signal trace 318C-1, second signal trace 318C-2, third signal trace 318C-3, fourth signal trace 318C-4, diode 319, backing 32, support member 33, through hole 331, adhesive member 34, connector 40. DETAILED DESCRIPTION

[0032] Exemplary embodiments are described in detail herein, with examples illustrated in the accompanying drawings. When the following description refers to the drawings, identical numerals in different figures represent identical or similar elements, unless otherwise indicated. The embodiments described in the following exemplary embodiments are not intended to represent all embodiments consistent with the present application. Rather, they are merely examples of devices, systems, apparatus, and methods consistent with certain aspects of the present application.

[0033] refer to Figure 1 As shown, the tumor electric field treatment system 100 includes an electric field generator 10, an adapter 20, and a plurality of paired electrode pads 30. The adapter 20 electrically connects the electric field generator 10 to each electrode pad 30. The electric field generator 10 generates an alternating current (AC) signal required for treatment. The adapter 20 receives the AC signal output from the electric field generator 10 and transmits the AC signal to the electrode pads 30. The paired electrode pads 30 are attached to the patient's body surface corresponding to the tumor area, applying the AC signal to the patient's tumor area to interfere with or prevent mitosis of the patient's tumor cells, thereby achieving the purpose of tumor treatment.

[0034] refer to Figure 2 and Figure 3As shown, the electrode sheet 30 includes an electrode array 31, a backing 32, several supports 33, and several adhesive members 34. The electrode array 31 is adhered to the backing 32 and electrically connected to the adapter 20 via wires (not shown). The electrode array 31 has thirteen electrode units 310 arranged in multiple rows and columns. A support member 33 is provided corresponding to each row of electrode units 310. The support member 33 has several through-holes 331 and is adhered to the backing 32 such that the through-holes 331 surround each electrode unit 310 in the corresponding row. The support member 33 supports and protects the electrode units 310. Adhesive members 34 are also provided corresponding to each row of electrode units 310, covering each row of electrode units 310 and the corresponding support members 33. The electrode sheet 30 is applied to the patient's body surface with the exposed side of the adhesive member 34 facing the patient. The side of the electrode sheet 30 facing the patient is defined as the front side, and the opposite side is defined as the back side. Backing 32 is a mesh nonwoven fabric coated with a biocompatible adhesive (not shown) on the front, ensuring it adheres tightly to the patient's body. Support 33 is made of foam. Adhesive 34 is double-sided and preferably made of a conductive gel to keep the skin moist and prevent skin problems.

[0035] refer to Figure 4 As shown, the thirteen electrode units 310 of the electrode array 31 are spatially arranged in five rows and five columns. The first and fifth rows each have two electrode units 310, and the middle three rows each have three electrode units 310. The electrode units 310 in the middle three rows are arranged in three columns, located in the first, third, and fifth columns of the electrode array 31, respectively. The two electrode units 310 in the first and fifth rows are arranged in two columns, located in the second and fourth columns of the electrode array 31, respectively. The electrode units 310 in the middle of the electrode array 31 are defined as central electrode units 310A, which include the three electrode units 310 located in the third column (also called the center column) and the middle three rows of the electrode array 31. The remaining electrode units 310 are located on the periphery of the electrode array 31 and are defined as peripheral electrode units 310B. All peripheral electrode units 310B surround all central electrode units 310A.

[0036] The electrode array 31 also includes several connecting portions 311 that connect adjacent electrode units 310. The arrangement of these connecting portions 311 structurally connects the electrode array 31 into a single entity while also meeting the wiring requirements of each electrode unit 310, ensuring that each electrode unit 310 can transmit the corresponding electrical signal. The connecting portions 311 give the electrode array 311 an axially symmetrical fishbone-like configuration. The central column serves as the axis of symmetry and the backbone of the electrode array 31, while the other columns serve as branches extending laterally from the backbone. Specifically, the three central electrode units 310A in the third column are interconnected along the column direction, while each peripheral electrode unit 310B is connected only to its nearest corresponding central electrode unit 310A along the row direction or diagonally. This arrangement minimizes the constraints imposed by the connecting portions 311 on each peripheral electrode unit 310B, allowing each peripheral electrode unit 310B to have greater freedom, thus preventing wrinkles around the peripheral electrode unit 310B during application. To further enhance the freedom of each peripheral electrode unit 310B, the backing 32 may also include selective grooves along the branches of the electrode array 31.

[0037] Specifically, the three central electrode units 310A are respectively located in the second row, the third row and the fourth row of the electrode array 31 and are all located in the third column, and are connected by corresponding connecting portions 311 along the column direction, and are located on the symmetry axis of the electrode array 31 to form the backbone of the electrode array 31; the peripheral electrode unit 310B located in the first row is connected to the central electrode unit 310A located in the second row through corresponding connecting portions 311 extending in an oblique line, forming two branches that are respectively inclined upward, and the two branches are arranged in an axisymmetric shape with respect to the symmetry axis of the electrode array 31; the peripheral electrode unit 310B located in the second row is connected to the central electrode unit 310A located in the second row through corresponding connecting portions 311 arranged in the row direction, forming two branches that are respectively extended in the row direction, and the two branches are arranged in an axisymmetric shape with respect to the symmetry axis of the electrode array 31; The peripheral electrode units 310B in the third row are connected to the central electrode units 310A in the third row via corresponding connections 311 arranged in the row direction, forming two branches extending in the row direction. These two branches are arranged symmetrically about the axis of symmetry of the electrode array 31. The peripheral electrode units 310B in the fourth row are also connected to the central electrode units 310A in the fourth row via corresponding connections 311 arranged in the row direction, forming two branches extending in the row direction. These two branches are arranged symmetrically about the axis of symmetry of the electrode array 31. The peripheral electrode units 310B in the fifth row are connected to the central electrode units 310A in the fourth row via corresponding connections 311 extending diagonally, forming two branches inclined downward. These two branches are arranged symmetrically about the axis of symmetry of the electrode array 31. Each of the above peripheral electrode units 310B is connected to a corresponding central electrode unit 310A located on the main trunk of the electrode array 31 via a corresponding connection 311. Each branch is radially arranged around the main trunk of the electrode array 31. In addition, the electrode array 31 is not provided with any other redundant connecting portions 311. The electrode units 310 of the electrode array 31 are connected by a minimum number of connecting portions 311, and each peripheral electrode unit 310B is connected only to one corresponding central electrode unit 310A. The peripheral electrode units 310B are not connected to each other. This allows for greater freedom of movement during application and prevents wrinkles around the electrode during application.

[0038] The electrode array 31 also includes a connection portion 312, which is located on the symmetry axis of the electrode array 31 and extends outward from the central electrode unit 310A located in the fourth row along the column direction. A plurality of gold fingers 3121 are provided on the front and back sides of the connection portion 312 for electrically connecting to a wire (not shown).

[0039] refer to Figure 5As shown, the electrode array 31 includes a substrate 313 arranged in a sheet shape from a hierarchical architecture. The substrate 313 is arranged as a supporting base plate in each electrode unit 310, each connecting part 311 and the wiring part 312. Each electrode unit 310, each connecting part 311 and the wiring part 312 is further provided with other structures on the front and / or bottom surface of the substrate 313, which will be described in detail later. The material of the substrate 313 is polyimide or polyester film, which has the characteristics of light weight, thin thickness, bendability, and high flexibility. For the convenience of description, the part of the substrate 313 corresponding to each electrode unit 310 is defined as the main body 3131. The main body 3131 is arranged in a circular shape. The part of the substrate 313 corresponding to each connecting part 311 and the wiring part 312 is called the connecting bar 3132. Each main body 3131 and each connecting bar 3132 are different parts of the entire substrate 313.

[0040] The electrode array 31 also includes a plurality of dielectric elements 314, which are disposed in a one-to-one correspondence on the front surface of each main body 3131. The dielectric elements 314 are arranged in a circular ring shape with an opening 3141 at their center, exposing the front surface of the corresponding main body 3131. Each electrode unit 310 is equipped with a temperature sensor 315, which is positioned within the opening 3141 and secured to the main body 3131. The temperature sensor 315 is then fully encapsulated within the opening 3141 of the dielectric element 314 using a sealant (not shown). In this embodiment, the dielectric elements 314 are ceramic sheets. The electrode array 31 also includes a plurality of support plates 316, which are arranged in a circular shape and are disposed in a one-to-one correspondence on the back surface of each main body 3131. The support plates 316 provide support and enhance the strength of the electrode units 310.

[0041] In this embodiment, the dielectric element 314 is a ceramic sheet. Optionally, the dielectric element 314 can also be in other forms, such as a polymer dielectric layer with high dielectric constant and low dielectric loss made of a thin film material with non-fixed crystal orientation, high flexibility and high toughness. The polymer dielectric layer can be formed on the main body 3131 by evaporation, sputtering or ion plating vapor deposition, printing, spraying or casting; in addition, the support plate 316 is optionally set.

[0042] refer to Figures 6 to 9As shown, the electrode array 31 is provided with a conductive pad 3171, a ground pad 3172, and a signal pad 3173 on the front surface of the main body 3131. The conductive pad 3171 is arranged in a ring shape, and the ground pad 3172 and the signal pad 3173 are located at the center of the conductive pad 3171 and are insulated from the conductive pad 3171. The dielectric element 314 is welded to the conductive pad 3171. The temperature sensor 315 has a ground terminal 3151 and a signal terminal 3152. The ground terminal 3151 is welded to the ground pad 3172, and the signal terminal 3152 is welded to the signal pad 3173. The ground terminal 3151 of each temperature sensor 315 is the ground terminal of the corresponding electrode unit 310, and the signal terminal 3152 of each temperature sensor 315 is the signal terminal of the corresponding electrode unit 310.

[0043] refer to Figure 7 and Figure 8 As shown, the front and back sides of the substrate 313 are provided with a plurality of conductive traces 318. The conductive trace 318 on the front side of the substrate 313 is primarily an AC signal trace 318A. The plurality of gold fingers 3121 on the connection portion 312 include a gold finger 3121 for transmitting AC signals. The AC signal trace 318A extends from the gold finger 3121 along the connection portion 312 and each connecting portion 311 to each main portion 3131, electrically connecting to a conductive pad 3171 on each main portion 3131 to transmit an AC signal to each electrode unit 310. Two parallel AC signal traces 318A are provided on each connecting portion 311 to ensure stable AC signal transmission.

[0044] Key References Figure 7 and Figure 8As shown, the plurality of conductive traces 318 on the back side of the substrate 313 further include a plurality of ground traces 318B and a plurality of signal traces 318C. Each ground trace 318B extends from a corresponding gold finger 3121 along the wiring portion 312 and the corresponding connecting portion 311 to a corresponding plurality of ground pads 3172 on the main body 3131 to electrically connect to the ground terminal 3151 of the corresponding temperature sensor 315, thereby grounding the ground terminal (not shown) of the corresponding temperature sensor 315. Each signal trace 318C extends from a corresponding gold finger 3121 along the wiring portion 312 and the corresponding connecting portion 311 to a corresponding signal pad 3173 on one or more main body 3131 to electrically connect to the signal terminal 3152 of the corresponding temperature sensor 315, thereby transmitting a DC signal to the corresponding temperature sensor 315 to detect the temperature at the corresponding electrode unit 310 and transmit the detected temperature signal to the adapter 20 or the electric field generator 10. The substrate 313 also includes a diode 319 on each main body portion 3131. The diode 319 is connected in series between the ground terminal 3151 of the temperature sensor 315 and the corresponding ground trace 318B. Specifically, the anode of the diode 319 is electrically connected to the ground terminal 3151 of the corresponding temperature sensor 315, and the cathode of the diode is electrically connected to the corresponding ground trace 318B. The main body 3131 also includes an anode pad (unnumbered) and a cathode pad (unnumbered) at the center of the conductive plate 3171, corresponding to each diode 319. The anode pad (unnumbered) is electrically connected to the ground pad 3172 via a corresponding pad trace (unnumbered). The provision of the diode 319 prevents reverse current flow, thereby preventing the detection signal from other electrode units 310 from affecting the temperature sensor 315.

[0045] In this embodiment, to obtain temperature detection signals from the thirteen temperature sensors 315, four ground traces 318B and four signal traces 318C are provided on the substrate 313. The corresponding temperature sensors 315 in the multiple electrode units 310 can share the corresponding ground traces 318B and corresponding signal traces 318C. The temperature detection signals of each temperature sensor 315 are obtained in batches by alternately grounding the ground traces 318B. The control method will be described in detail later. Compared to providing an independent signal trace for each temperature sensor 315, this wiring method reduces the total number of conductive traces 318, easing the wiring difficulty of the substrate 313, simplifying the manufacturing process of the electrode array 31, and also improving the flexibility of the electrode array 31 and the fit during application. The connection portion 312 is provided with ten gold fingers 3121, of which four gold fingers 3121 are respectively connected to the four ground traces 318B in a one-to-one correspondence; four gold fingers 3121 are respectively connected to the four signal traces 318C in a one-to-one correspondence, and one gold finger 3121 is connected to the AC signal trace 318A; one gold finger 3121 is connected to the shielding layer (not shown) of the conductive line (not shown) and is grounded for electromagnetic shielding and to prevent signal interference.

[0046] Continue to refer Figures 6 to 9 As shown, the wiring scheme of the ground trace 318B and the signal trace 318C will be described in detail below. In terms of spatial structure, the thirteen electrode units 310 are labeled as electrode units M1-M13 from top to bottom and from left to right according to their positions. Specifically, the two electrode units 310 in the first row are electrode units M1 and M2 respectively; the three electrode units 310 in the second row are electrode units M3, M4, and M5 respectively; the three electrode units 310 in the third row are electrode units M6, M7, and M8 respectively; the three electrode units 310 in the fourth row are electrode units M9, M10, and M11 respectively; and the two electrode units 310 in the fifth row are electrode units M12 and M13 respectively. The four ground traces 318B are respectively a first ground trace 318B- 1 , a second ground trace 318B- 2 , a third ground trace 318B- 3 , and a fourth ground trace 318B- 4 ; the four signal traces 318C are respectively a first signal trace 318C- 1 , a second signal trace 318C- 2 , a third signal trace 318C- 3 , and a fourth signal trace 318C- 4 .

[0047] Key References Figure 7 As shown, from the back side of the substrate 313, the wiring scheme of the four ground traces 318B is as follows:

[0048] The grounding terminals 3151 of the temperature sensors 315 of the electrode units M1, M2, and M13 are short-circuited in parallel to the first ground trace 318B-1. The three electrode units 310 are located at both ends of the electrode sheet 30 in terms of spatial structure and are all peripheral electrode units 310B. The specific routing of the first ground trace 318B-1 is as follows: it extends upward from the connection portion 312 and is divided into two branches near the electrode unit M10. One branch passes through the corresponding connection portion 311 and connects to the temperature sensor 315 of the electrode unit M13. 15; the other branch passes through the electrode units M10, M7, M4 and the corresponding connecting portion 311 in sequence and then splits into two branches that continue to extend upward, one of which passes through the corresponding connecting portion 311 and is connected to the grounding pad 3172 corresponding to the grounding terminal 3151 of the temperature sensor 315 of the electrode unit M1, and the other branch passes through the corresponding connecting portion 311 and is connected to the grounding pad 3172 corresponding to the grounding terminal 3151 of the temperature sensor 315 of the electrode unit M2.

[0049] The ground terminals 3151 of the temperature sensors 315 of the electrode units M3, M4, and M5 are short-circuited in parallel to the second ground trace 318B-2. These three electrode units 310 are spatially located in the second row of the electrode sheet 30, adjacent to each other. The specific routing of the second ground trace 318B-2 is as follows: it extends upward from the wiring portion 312, passes through the electrode units M10, M7, and M4 and the corresponding connection portion 311 in sequence, and then connects to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M4. At the same time, it splits into two branches to the left and right, respectively. One branch passes through the corresponding connection portion 311 to connect to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M3, and the other branch passes through the corresponding connection portion 311 to connect to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M5.

[0050] The ground terminals 3151 of the temperature sensors 315 of the electrode units M6, M7, and M8 are short-circuited in parallel to the third ground trace 318B-3. These three electrode units 310 are spatially located in the third row of the electrode sheet 30, adjacent to one another. The specific routing of the third ground trace 318B-3 is as follows: it extends upward from the wiring portion 312, passes through the electrode units M10 and M7, and the corresponding connection portion 311, and then connects to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M7. At the same time, it splits into two branches to the left and right, respectively. One branch passes through the corresponding connection portion 311 to connect to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M6, and the other branch passes through the corresponding connection portion 311 to connect to the ground pad 3172 corresponding to the ground terminal 3151 of the temperature sensor 315 of the electrode unit M8.

[0051] The ground terminals 3151 of the temperature sensors 315 of the electrode units M9, M10, M11, and M12 are short-circuited in parallel to the fourth ground trace 318B-4. These four electrode units 310 are located in the fourth row and the adjacent fifth row of the electrode sheet 30 in terms of spatial structure and are adjacent to each other. The specific routing method of the fourth ground trace 318B-4 is as follows: it extends upward from the wiring portion 312 and is divided into two branches near the electrode unit M10, one of which passes through the corresponding connection portion 311 and is connected to the ground pad 3172 corresponding to the ground end 3151 of the temperature sensor 315 of the electrode unit M12, and the other branch continues to extend and is connected to the ground pad 3172 corresponding to the ground end 3151 of the temperature sensor 315 of the electrode unit M10, and then is divided into two branches to the left and right sides respectively, one of which passes through the corresponding connection portion 311 and is connected to the ground pad 3172 corresponding to the ground end 3151 of the temperature sensor 315 of the electrode unit M9, and the other branch passes through the corresponding connection portion 311 and is connected to the ground pad 3172 corresponding to the ground end 3151 of the temperature sensor 315 of the electrode unit M11.

[0052] The ends of the four ground traces 318B on the connection portion 312 all pass through corresponding portions of the connection portion 312 and are then connected one-to-one with four corresponding gold fingers 3121 on the front of the connection portion 312. When the electrode unit 310 is provided with a diode 319 corresponding to each temperature sensor 315, the corresponding ground trace 318B must be electrically connected to the ground pad 3172 corresponding to the ground terminal 3151 of the corresponding temperature sensor 315 through the corresponding diode 319 and the corresponding anode pad (unnumbered) and cathode pad (unnumbered) of the diode 319.

[0053] Key References Figure 8 As shown, from the back side of the substrate 313, the wiring scheme of the four signal traces 318C is as follows:

[0054] The signal end 3152 of the temperature sensor 315 of the electrode unit M12 is connected to the first signal trace 318C-1; the specific routing method of the first signal trace 318C-1 is: extending upward from the wiring part 312 and then passing through the corresponding connection part 311 to connect to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M12.

[0055] The signal terminals 3152 of the temperature sensors 315 of the electrode units M1, M3, M6, and M9 are connected in parallel to the second signal trace 318C-2. The four electrode units 310 are all located on the left side of the symmetry axis of the electrode array 31 in terms of spatial structure ( Figure 8on the right side); the specific routing method of the second signal trace 318C-2 is as follows: it extends upward from the wiring portion 312, passes through the electrode units M10, M9 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M9, then returns and passes through the electrode units M10, M7, M6 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M6, then returns and passes through the electrode units M7, M4, M3 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M3, and finally returns and passes through the electrode unit M4 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M1, without any branches in the middle.

[0056] The signal terminals 3152 of the temperature sensors 315 of the electrode units M2, M5, M8, and M11 are connected in parallel to the third signal trace 318C-3. The four electrode units 310 are all located on the right side of the symmetry axis of the electrode array 31 in terms of spatial structure ( Figure 8 on the left side); the specific routing method of the third signal trace 318C-3 is as follows: it extends upward from the wiring portion 312, passes through the electrode units M10, M11 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M11, then returns and passes through the electrode units M10, M7, M8 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M8, then returns and passes through the electrode units M7, M4, M5 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M5, and finally returns and passes through the electrode unit M4 and the corresponding connection portion 311, and is connected to the signal pad 3173 corresponding to the signal end 3152 of the temperature sensor 315 of the electrode unit M2, without any branches in the middle.

[0057] The signal terminals 3152 of the temperature sensors 315 of the electrode units M4, M7, M10, and M13 are connected in parallel to the fourth signal trace 318C-4. In terms of spatial structure, three of these four electrode units 310 are located on the axis of symmetry of the electrode array 31, and one is located near the axis of symmetry. The specific routing of the fourth signal trace 318C-4 is as follows: it is divided into two branches at the connection portion 312. One branch extends upward along the axis of symmetry and, as it passes through the electrode units M10, M7, and M4 and the corresponding connection portions 311, is sequentially connected to the signal pads 3173 corresponding to the signal terminals 3152 of the temperature sensors 315 of the electrode units M10, M7, and M4. The other branch passes through the corresponding connection portion 311 and is connected to the signal pad 3173 corresponding to the signal terminal 3152 of the temperature sensor 315 of the electrode unit M13.

[0058] The ends of the four signal traces 318C on the connection portion 312 are connected to four corresponding gold fingers 3121 on the back side of the connection portion 312 in a one-to-one correspondence.

[0059] It is understood that although the ground traces 318B and signal traces 318C are mostly routed on the back side of the substrate 313, the ground traces 318B need to pass through corresponding portions of the substrate 313 and electrically connect to corresponding ground pads 3172 on the front side of the substrate 313. Furthermore, the four ground traces 318B and four signal traces 318C are arranged in parallel on the back side of the substrate 313 without interfering with each other. However, due to routing requirements, the ground traces 318B and signal traces 318C inevitably intersect at some locations on the substrate 313. To avoid interference, the ground traces 318B or signal traces 318C at the intersections pass through corresponding portions of the substrate 313 to the front side of the substrate 313 for jumpering, and then pass back to the back side of the substrate 313 for continued routing. Therefore, shorter portions of the ground trace 318B and the signal trace 318C also exist on the front of the substrate 313 , and the ground trace 318B and the signal trace 318C on the front of the substrate 313 and the AC signal trace 318A also do not interfere with each other.

[0060] The following combination Figure 9As shown, the temperature measurement and control method of the electrode sheet 30 of the present application is described in detail. The wire (not shown) of the electrode sheet 30 is plugged into the connector 40 of the adapter 20 to realize the circuit connection between the electrode sheet 30 and the adapter 20. In terms of circuit arrangement, thirteen electrode units 310 are arranged on the substrate 313 in the form of a two-dimensional array, arranged in four rows and four columns. Specifically, the first row has three electrode units 310, namely electrode units M1, M2, and M13, and these three electrode units 310 are located in the second to fourth columns in sequence; the second row has three electrode units 310, namely electrode units M3, M5, and M4, and these three electrode units 310 are located in the second to fourth columns in sequence; the third row has three electrode units 310, namely electrode units M6, M8, and M7, and these three electrode units 310 are located in the second to fourth columns in sequence; the fourth row has four electrode units 310, namely electrode units M12, M9, M11, and M10, and these four electrode units 310 are located in the first to fourth columns in sequence. The four ground traces 318B are respectively connected to the ground terminals 3151 of the multiple temperature sensors 315 in the corresponding rows, and the signal terminals 3152 of the multiple temperature sensors 315 connected to each ground trace 318B are respectively connected to different signal traces 318C, that is, the signal terminals 3152 of each temperature sensor 315 in each row are respectively connected to different detection channels in the adapter 20 through different signal traces 318C; each of the four signal traces 318C is connected to the signal terminals 3151 of at least one temperature sensor 315. The signal terminals 3152 of each temperature sensor 315 are connected to different ground traces 318B via the same signal trace 318C. The signal terminals 3152 of each temperature sensor 315 in the same column are connected to the same detection channel in the adapter 20 via the same signal trace 318B, while the signal terminals 3152 of each temperature sensor 315 in different columns are connected to different detection channels in the adapter 20 via different signal traces 318C. During temperature measurement, all four signal traces 318C remain conductive, and then the ground trace 318B is turned on in turn, so that the temperature detection signals of each temperature sensor 315 in each row can be obtained in a time-sharing manner.

[0061] The adapter 20 includes a controller 21, multiple analog-to-digital conversion modules 22 connected to the controller 21, multiple sets of voltage dividers 24 and multiple sets of ground switches 25 corresponding one-to-one with the multiple analog-to-digital conversion modules 22, a communication unit 23, and a power supply module 26 connected to the communication unit 23, the controller 21, and the multiple analog-to-digital conversion modules 22. The power supply module 26 provides a DC power supply VCC to the electronic components of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered). The multiple circuit lines (unnumbered) are electrically connected to the multiple ground traces 318B, multiple signal traces 318C, and AC signal traces 318A in the substrate 313 of the electrode sheet 30 through the wires of the corresponding electrode sheet 30. The multiple circuit lines (unnumbered) include multiple AC lines 27 that transmit alternating current signals to the corresponding electrode sheets 30 and are electrically connected to the AC signal traces 318A in the substrate 313 of the corresponding electrode sheets 30, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple signal traces 318C in the substrate 313 of the corresponding electrode sheets 30 and are used to supply power to the temperature sensors 315 of the electrode sheets 30 or transmit the temperature detection signals of the electrode sheets 30, and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground traces 318B in the substrate 313 of the corresponding electrode sheets 30. The number P of circuit lines electrically connected between the adapter 20 and one electrode sheet 30 is equal to the sum of the number M of row groups and the number N of column groups of the electrode units 310 of the electrode sheet 30 in the circuit connection plus 1; the number H of circuits electrically connected between the adapter 20 and X electrode sheets 30 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 30, that is, H=XP=X*(M+N+1). The number of groups of grounding switches 25 is related to the number of electrode sheets 30. The number of groups of grounding switches 25 is not less than the number of electrode sheets 30. Preferably, the number of groups of grounding switches 25 is the same as the number of electrode sheets 30. The following is a detailed description taking the electrical connection between one electrode sheet 30 and the adapter 20 as an example.

[0062] Each group of grounding switches 25 is provided with a plurality of grounding switches 25, and the plurality of grounding switches 25 are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multi-path grounding traces 318B of the corresponding electrode sheet 30, and are configured to control the conduction or disconnection of the multi-path grounding traces 318B. The circuit lines (not numbered) that are electrically connected to the multi-path grounding traces 318B of the electrode sheet 30 are grounded at one end close to the grounding switch 25. The number of grounding switches 25 in each group of grounding switches 25 is related to the number of grounding traces 318B of the substrate 313 of the corresponding electrode sheet 30, and the two are equal in this embodiment. Figure 9As shown, in this embodiment, each group of grounding switches 25 includes multiple grounding switches 25, four in this embodiment, namely a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3, and a fourth grounding switch 25-4. The multiple grounding switches 25 in each group control the closing or opening of a corresponding grounding trace 318B of a corresponding electrode sheet 30.

[0063] Specifically, in terms of the circuit connection of the electrode unit 310, the ground ends 3151 of the temperature sensors 315 of the three electrode units M1, M2, and M13 located in the first row are short-circuited in parallel to the first ground trace 318B-1, the ground ends 3151 of the temperature sensors 315 of the three electrode units M3, M5, and M4 located in the second row are short-circuited in parallel to the second ground trace 318B-2, the ground ends 3151 of the temperature sensors 315 of the three electrode units M6, M8, and M7 located in the third row are short-circuited in parallel to the third ground trace 318B-3, and the ground ends 3151 of the temperature sensors 315 of the four electrode units M12, M9, M11, and M10 located in the fourth row are short-circuited in parallel to the fourth ground trace 318B-4. The first grounding switch 25-1 is used to control the closing or opening of the first grounding trace 318B-1 of the corresponding electrode sheet 30, thereby controlling the power on and off of each temperature sensor 315 of each electrode unit 310 in the first row of the electrode sheet 30; the second grounding switch 25-2 is used to control the closing or opening of the second grounding trace 318B-2 of the electrode sheet 30, thereby controlling the power on and off of each temperature sensor 315 of each electrode unit 310 in the second row of the electrode sheet 30; the third grounding switch 25-3 is used to control the closing or opening of the third grounding trace 318B-3 of the electrode sheet 30, thereby controlling the power on and off of each temperature sensor 315 of each electrode unit 310 in the third row of the electrode sheet 30; the fourth grounding switch 25-4 is used to control the closing or opening of the fourth grounding trace 318B-4 of the electrode sheet 30, thereby controlling the power on and off of each temperature sensor 315 of each electrode unit 310 in the fourth row of the electrode sheet 30. The grounding switch 25 may be a mechanical switch, such as a relay, or an electronic switch. Each grounding switch 25 may be opened and closed by the controller 21 of the adapter 20 .

[0064] In this embodiment, the multiple groups of grounding switches 25 are all electronic switches. The controller 21 is in communication with the multiple groups of grounding switches 25 and is configured to sequentially and cyclically control the opening and closing states of the multiple grounding switches 25 in each group of grounding switches 25, thereby sequentially and individually connecting each of the multiple grounding traces 318B of the corresponding electrode sheet 30. This allows for sequential, time-sharing acquisition of temperature signals from the patient's body surface detected by all temperature sensors 315 on the electrode sheet 30 during periods when the corresponding electrode sheet 30 stops applying an AC signal. The number of grounding switches 25 in each group is greater than or equal to the number of grounding traces 318B on the substrate 313 of the corresponding electrode sheet 30. In this embodiment, the number of grounding switches 25 in each group is equal to the number of grounding traces 318B in the corresponding electrode sheet 30.

[0065] In this embodiment, each group of analog-to-digital conversion modules 22 is electrically connected one by one to each signal trace 318C of the substrate 313 in the corresponding electrode sheet 30 through the multi-channel circuit lines (unnumbered) in the adapter 20, and is configured to receive the temperature detection signal transmitted from the multi-channel signal trace 318C of the corresponding electrode sheet 30, and convert the temperature detection signal from an analog signal to a digital signal. Each group of analog-to-digital conversion modules 22 includes a plurality of detection channels A, B, C, and D, and each detection channel A, B, C, and D is used to connect to a corresponding signal trace 318C in the multi-channel signal trace 318C. The number of detection channels in each group of analog-to-digital conversion modules 22 is related to the number of column groups of the electrode units 310 of the corresponding electrode sheet 30 in the circuit connection. Specifically, the number of detection channels in each group of analog-to-digital conversion modules 22 is not less than the number of column groups of the electrode units 310 of the corresponding electrode sheet 30 in the circuit connection. As Figure 9As shown, each group of analog-to-digital conversion modules 22 includes a total of four detection channels A, B, C, and D, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. The signal end 3152 of the temperature sensor 315 of the single electrode unit M12 located in the first column is connected to the first signal trace 318C-1, the signal end 3152 of the temperature sensor 315 of the four electrode units M1, M3, M6, and M9 located in the second column are respectively connected in parallel to the second signal trace 318C-2, the signal end 3152 of the temperature sensor 315 of the four electrode units M2, M5, M8, and M11 located in the third column are respectively connected in parallel to the third signal trace 318C-3, and the signal end 3152 of the temperature sensor 315 of the four electrode units M13, M4, M7, and M10 located in the fourth column are respectively connected in parallel to the fourth signal trace 318C-4. The first detection channel A is connected to the first signal trace 318C-1, the second detection channel B is connected to the second signal trace 318C-2, the third detection channel C is connected to the third signal trace 318C-3, and the fourth detection channel D is connected to the fourth signal trace 318C-4. Each detection channel A, B, C, and D is used to receive the temperature detection signal collected by the temperature sensor 315 of the electrode unit 310 connected to the corresponding signal trace 318C. In addition, each detection channel A, B, C, and D is connected to a power supply module 26 for providing a detection voltage to the detection channel A, B, C, and D via a corresponding voltage divider resistor 24 within the adapter 20. The power supply module 26 provides a DC signal.

[0066] In this embodiment, the communication unit 23 is configured to acquire multiple sets of digital signals output by the analog-to-digital conversion modules 22 and transmit the digital signals to the electric field generator 10. The electric field generator 10 is further configured to control and adjust the voltage, current, or power of the AC signal provided to the multiple electrode units 310 of the electrode sheet 30 based on the received digital signals. For example, when any of the multiple received digital signals exceeds a preset threshold value stored in the controller 21, it indicates that the temperature of the human body surface to which the corresponding dielectric element 314 is applied, as detected by at least one temperature sensor 315 in the electrode sheet 30, exceeds a preset threshold temperature (e.g., 41°C, 42°C, etc.). At this point, the voltage, current, or power of the AC signal output by the electric field generator 10 can be appropriately reduced to prevent the electrode units 310 of the electrode sheet 30 from overheating when the AC signal is applied, thereby preventing low-temperature burns on the patient's skin. The preset threshold temperature and preset threshold value can be determined based on a human safety threshold. The communication unit 23 is controlled by the controller 21 and serially transmits the digital signals converted by the multiple sets of analog-to-digital conversion modules 22. In this embodiment, the preset temperature threshold may be a value within the range of 36°C-45°C.

[0067] When an AC signal needs to be applied to each electrode unit 310 of the corresponding electrode sheet 30, the corresponding four grounding switches 25-1 to 25-4 are all disconnected, and the electric field generator 10 outputs the AC signal to the corresponding AC line 27 in the adapter 20, and the AC signal is applied to the dielectric element 314 of each electrode unit 310 through the AC signal trace 318A connected to the AC line 27.

[0068] When it is necessary to collect the temperature detection signal of each temperature sensor 315 in the corresponding electrode sheet 30, the electrical connection between the AC signal trace 318A of the electrode sheet 30 and the AC line 27 of the adapter 20 is disconnected, and the four signal traces 318C are always connected. The first grounding switch 25-1 is closed first, and the other grounding switches 25-2 to 25-4 are all opened. The three detection channels B, C and D of the analog-to-digital conversion module 22 can obtain the temperature detection signal at the same time. Figure 9 Then close the second grounding switch 25-2, and the other grounding switches 25-1, 25-3 and 25-4 are all disconnected, and the three detection channels B, C and D of the analog-to-digital conversion module 22 can obtain the temperature detection signals of the three electrode units M1, M2 and M13 in the first row shown in FIG. Figure 9 The temperature detection signals of the three electrode units M3, M4, and M5 in the second row are shown in FIG; then the third grounding switch 25-3 is closed, and the other grounding switches 25-1, 25-2, and 25-4 are all disconnected, and the three detection channels B, C, and D of the analog-to-digital conversion module 22 can be obtained simultaneously. Figure 9 Finally, the fourth grounding switch 25-4 is closed, and the other grounding switches 25-1, 25-2 and 25-3 are all disconnected. The four detection channels A, B, C and D of the analog-to-digital conversion module 22 can obtain the temperature detection signals of the three electrode units M6, M8 and M7 in the third row shown in FIG. Figure 9 The temperature detection signals of the four electrode units M12, M9, M11, and M10 in the fourth row are shown in FIG. In this way, the temperature detection signals of all temperature sensors 315 can be collected.

[0069] The communication unit 23 is controlled by the controller 21 and serially transmits the digital signal converted by the analog-to-digital conversion module 22, and sends the digital signal to the electric field generator 10. When any of the multiple digital signals received by the electric field generator 10 exceeds a preset threshold, the voltage, current, or power of the AC signal output by the electric field generator 10 can be appropriately reduced to prevent the temperature of any electrode unit 310 from being too high and causing low-temperature burns to the patient's skin.

[0070] The above is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present application should be included in the scope of protection of the present application.

Claims

1. A tumor electric field treatment system comprising an electric field generator and a plurality of pairs of electrodes electrically connected to the electric field generator, wherein the electrode sheets comprise an electrode array, characterized in that: The electrode array includes a trunk and several branches extending radially from the trunk to the surrounding areas thereof, the trunk is provided with several central electrode units and a connecting portion connecting two adjacent central electrode units; the branch is provided with a peripheral electrode unit and a connecting portion connecting the peripheral electrode unit to the trunk, and each peripheral electrode unit is only connected to the central electrode unit closest to it through the corresponding connecting portion; the electrode array also has an AC signal trace for transmitting alternating current signals to each electrode unit, several ground traces and several signal traces, and the AC signal traces are independently arranged; the several electrode units are divided into multiple rows and columns in terms of circuit connection, and the ground ends of each electrode unit in each row are connected in parallel to the same ground trace, and the signal ends of each electrode unit in each column are connected in parallel to the same On one signal trace, the AC signal input end of each electrode unit is connected in parallel to the AC signal trace and is independent of its signal end; when collecting the temperature detection signal, the AC signal trace is disconnected, and each signal trace remains conductive, and each ground trace is grounded in turn to collect the temperature detection signal of each electrode unit in the corresponding row group in a time-sharing and row-by-row manner; when applying an AC signal, each ground trace is disconnected, and the AC signal trace is conductive and transmits the AC signal to the AC signal input end of each electrode unit; the electrode array is provided with a flexible substrate, and most of the ground traces and each of the signal traces are arranged on the back of the substrate; each electrode unit is provided with a conductive disk located on the front of the substrate, and the AC signal trace is arranged on the front of the substrate and connected to each of the conductive disks.

2. The tumor treating field system according to claim 1, wherein: The tumor electric field therapy system also includes an AC line, several grounding switches and several detection channels. The AC line is connected to the AC signal trace, the grounding trace is connected to the grounding switch in a one-to-one correspondence, and the signal trace is connected to the detection channel in a one-to-one correspondence. The detection channels are all turned on when collecting the temperature detection signal of the electrode unit, and the grounding switches are closed individually and sequentially when collecting the temperature detection signal of the electrode unit.

3. The tumor treating field system according to claim 1, wherein: Each electrode unit is provided with a temperature sensor, which is provided with a ground terminal and a signal terminal. The ground terminal of the temperature sensor is the ground terminal of the corresponding electrode unit, and the signal terminal of the temperature sensor is the signal terminal of the corresponding electrode unit.

4. The tumor treating field system according to claim 1, wherein: There are thirteen electrode units and four ground traces, wherein each of the three ground traces is respectively connected to the ground ends of the three electrode units, and the other ground trace is connected to the ground ends of the remaining four electrode units; there are four signal traces, wherein each of the three signal traces is respectively connected to the signal ends of the four electrode units, and the other signal trace is only connected to the signal end of the remaining one electrode unit.

5. The tumor treating field system according to claim 4, wherein: The thirteen electrode units are spatially arranged into five rows and five columns, with two electrode units each in the first row and the fifth row and located on the second column and the fourth column respectively, and three electrode units each in the middle three rows and located on the first column, the third column and the fifth column respectively; in terms of circuit connection, the ground ends of the two electrode units in the first row and any electrode unit in the fifth row are each connected to one ground trace; the ground ends of the three electrode units in the second row are each connected to one ground trace; the ground ends of the three electrode units in the third row are each connected to one ground trace; the ground ends of the three electrode units in the fourth row and the remaining electrode unit in the fifth row are each connected to one ground trace.

6. The tumor treating field system according to claim 5, wherein: In terms of circuit connection, the signal end of any electrode unit located in the fifth row is connected to one signal trace; the signal end of each of the three electrode units located in the third column and the remaining electrode unit located in the fifth row is connected to one signal trace; the signal end of each of the three electrode units located in the first column and any electrode unit located in the first row is connected to one signal trace; the signal end of each of the three electrode units located in the fifth column and the remaining electrode unit located in the first row is connected to one signal trace.

7. The tumor treating field system according to claim 1, wherein: Part of the ground traces and / or part of the signal traces pass through the substrate to the front side of the substrate for jumpering and then pass back to the back side of the substrate for further arrangement.

8. The tumor treating field system according to claim 1, wherein: The electrode array is provided with a wiring portion, and a plurality of gold fingers are provided on the front and back sides of the wiring portion respectively. The end of each ground trace passes through the wiring portion and is connected to the corresponding gold finger located on the front side of the wiring portion, and the end of each signal trace is connected to the corresponding gold finger located on the back side of the wiring portion.

9. The tumor treating field system according to claim 1, wherein: The electrode unit is provided with a dielectric element electrically connected to the conductive disk.

10. The tumor treating field system according to claim 3, wherein: The electrode unit is provided with a diode connected in series between the ground terminal of the temperature sensor and the ground trace.

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