Tumor electric field treatment system and temperature detection method

Abstract

The invention provides a tumor electric field treatment system which comprises at least one pair of electrode plates and an electric field generator, each electrode plate is provided with a flexible circuit board, a plurality of electrode units and a handshake chip, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The flexible circuit board is provided with multiple paths of grounding wires connected to the grounding ends and multiple paths of dual-purpose signal wires connected to the signal ends, and the dielectric elements of the same electrode unit are in short circuit with the signal ends. The electric field generator sends a handshake signal to the handshake chip, the handshake chip sends a feedback signal to the electric field generator after receiving the handshake signal, and the electric field generator transmits an alternating current signal to each dielectric element through each dual-purpose signal line in a first mode after receiving the feedback signal; in the second mode, direct current signals or temperature signals detected by the temperature sensors are transmitted to the signal ends through the dual-purpose signal lines, and the grounding lines are in an off state in the first mode and are in an on state in the second mode.

Description

[0001] This application is a divisional application filed by the applicant on October 25, 2024, entitled "Electrode Sheet, Tumor Electric Field Therapy System and Temperature Detection and Signal Control Method", with application number CN202411499210.X. Technical Field

[0002] This application relates to tumor electric field therapy (TTF) technology, and more particularly to a tumor electric field therapy system and a temperature detection method. Background Technology

[0003] Tumor electric field therapy is a method of treating tumors by using low-intensity, medium-to-high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis during mitosis.

[0004] Compared to traditional cancer treatments, TTF has an innovative mechanism of action. Certain physiological characteristics of tumor cells, such as their geometry and high-frequency mitosis, make them susceptible to TTF. TTF disrupts the normal aggregation of microtubules by applying directional forces to intracellular polar particles (such as macromolecules and organelles). These processes can lead to physical damage to the cell membrane and apoptosis. During the telophase of mitosis, the morphology of the cleavage groove leads to an uneven distribution of the electric field around it. Under the influence of TTF, the electric field strength at the cleavage groove is significantly enhanced, causing charged substances in the cell to move towards the cleavage groove, interfering with or even destroying cell structure formation, ultimately leading to cell division failure and apoptosis.

[0005] In existing tumor electric field therapy systems, an electric field generator transmits an alternating current signal for tumor electric field therapy to electrode pads. These pads then apply an alternating electric field to the patient's tumor site for treatment. When the therapeutic electric field is applied to the patient's body, heat accumulates at the application site, causing a corresponding increase in temperature. Therefore, it is necessary to monitor the temperature at the application site. If the temperature becomes too high, the electric field intensity must be adjusted promptly to avoid the risk of burns to the patient's skin.

[0006] Tumor electric field therapy systems include at least one pair of electrode pads, each containing multiple electrode units. Even when the same alternating current signal is applied to each electrode unit, the heat generated on each unit will vary depending on its location. This means the temperature of each electrode unit across the entire electrode pad will not be completely uniform. Consequently, some electrode units may exceed a preset temperature while others remain at a normal temperature. To ensure a sufficiently long application time for tumor electric field therapy while avoiding low-temperature burns to the patient's skin, individual control of overheated electrode units is necessary. However, with existing electrode pads, individual control of electrode units requires a conductive trace for each unit within the electrode pad's substrate. This increases the number of conductive traces within the substrate, making the electrode pad less flexible, and also thickens the cables connecting to the electrode pad, increasing its overall weight and hindering proper application.

[0007] Therefore, it is necessary to provide a tumor electric field therapy system and a temperature detection method. Summary of the Invention

[0008] The purpose of this application is to provide a tumor electric field therapy system.

[0009] To achieve the above objectives, this application provides the following technical solution: a tumor electric field therapy system, comprising: at least one pair of electrode pads, each electrode pad having a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip; each electrode unit including a dielectric element and a temperature sensor having a signal terminal and a ground terminal; the flexible circuit board having multiple grounding lines connected to each of the ground terminals and multiple dual-purpose signal lines connected to each of the signal terminals, wherein the dielectric element of the same electrode unit is short-circuited to the signal terminal; and an electric field generator, the electric field generator having a second controller, the second controller sending a handshake signal to the handshake chip; the handshake chip receiving the handshake signal sending a feedback signal to the second controller; and the electric field generator receiving the feedback signal and confirming that the electrode pads are properly connected, transmitting AC signals to each of the dielectric elements through each of the dual-purpose signal lines in a first mode, and transmitting DC signals or temperature signals detected by each of the temperature sensors to the signal terminals detected by each of the temperature sensors through each of the dual-purpose signal lines in a second mode, wherein each of the grounding lines is in an open state in the first mode and in a conductive state in the second mode.

[0010] Furthermore, the electrode units are arranged in multiple rows and columns in the circuit. The grounding terminals of the temperature sensors in the same row group are all connected to the same grounding line. The grounding terminals of the temperature sensors in different row groups are connected in parallel through different grounding lines. In the second mode, the multiple grounding lines are turned on individually in sequence. The signal terminals of the temperature sensors in the same column group are all connected to the same dual-purpose signal line. The signal terminals of the temperature sensors in different column groups are connected in parallel through different dual-purpose signal lines.

[0011] Furthermore, the temperature signals detected by the temperature sensors are sampled line by line, and the sampled temperature signals detected by the temperature sensors are used to characterize the type of the electrode sheet or whether the electrode sheet has a temperature abnormality.

[0012] Furthermore, the electrode unit also includes a diode connected in series with the temperature sensor, and the temperature sensor is grounded through the diode.

[0013] Furthermore, the system also includes an adapter, which comprises multiple sets of bidirectional switching switches respectively corresponding to each of the electrode plates. Multiple bidirectional switching switches in each set are electrically connected to the multiple dual-purpose signal lines of the electrode plate. The adapter also includes an AC signal line and multiple sets of analog-to-digital converters respectively corresponding to each of the electrode plates. Each set of analog-to-digital converters has multiple detection channels. The bidirectional switching switch has an input terminal electrically connected to the AC signal line and a sampling terminal electrically connected to the corresponding detection channel. The bidirectional switching switch switches between activating its input terminal and activating its sampling terminal, causing the corresponding dual-purpose signal line to switch between being connected to the AC signal line and being connected to the detection channel.

[0014] Furthermore, the adapter also includes multiple sets of grounding switches respectively corresponding to each of the electrode plates. Multiple grounding switches in each set of grounding switches are electrically connected to multiple grounding wires of the electrode plate and are configured to control the conduction or disconnection of the multiple grounding wires.

[0015] Furthermore, the adapter also includes a first controller, which is connected to multiple sets of grounding switches and multiple sets of bidirectional switching switches respectively. The first controller is configured to: in a second mode, configure the switching state of each grounding switch in the corresponding set of grounding switches to sequentially and individually turn on each of the grounding lines of the electrode sheet; and control the switching state of each bidirectional switching switch in the corresponding set of bidirectional switching switches to connect each of the dual-purpose signal lines of the electrode sheet to the corresponding detection channel respectively.

[0016] Furthermore, the first controller is configured to: configure the switching state of the corresponding group of grounding switches and the switching state of the corresponding group of bidirectional switching switches when receiving a handshake signal sent by the electric field generator, so as to power on the handshake chip, send the handshake signal to the handshake chip, and determine whether handshake communication with the handshake chip has been completed based on the feedback signal of the handshake chip, and after the handshake communication is completed, configure the switching state of each grounding switch of the corresponding group of grounding switches and the switching state of each bidirectional switching switch of the corresponding group of bidirectional switching switches, so as to enable the corresponding group of analog-to-digital converters to sample the temperature signals detected by each temperature sensor in the corresponding row group.

[0017] Furthermore, the adapter also includes a first communication unit configured to acquire multiple sets of temperature signals collected by the analog-to-digital converter and send the digital signals to the electric field generator. The electric field generator is further configured to control or adjust the AC signal applied to a corresponding electrode unit among the multiple electrode units of the electrode sheet according to the received temperature signals.

[0018] This application also provides a temperature detection method applied to the aforementioned tumor electric field therapy system. The method includes the following steps: performing handshake communication with the handshake chip to determine the connection status of the corresponding electrode pads; when each electrode pad is normally connected, configuring multiple dual-purpose signal lines of the electrode pads to be connected to the corresponding detection channels respectively, and configuring multiple ground lines to be individually turned on in sequence, so as to sample the temperature signal detected by the electrode unit in each row group row by row.

[0019] The flexible circuit board of the electrode pads in the tumor electric field therapy system of this application is equipped with multiple dual-purpose signal lines, which can transmit AC signals in the first mode and transmit DC signals or collect temperature detection signals of each electrode unit in the second mode. There is no need to set up separate conductive traces for transmitting AC signals only, which can reduce the number of wire cores of the wires connecting the electrode pads and simplify the wiring design of the flexible circuit board of the electrode pads.

[0020] The above description is only an overview of the technical solution of this application. In order to better understand the technical means of this application and to implement it in accordance with the contents of the specification, and to make the above and other objects, features and advantages of this application more obvious and understandable, the following are specific embodiments of this application. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of a tumor electric field therapy system according to an embodiment of the present application, which shows a schematic diagram of the spatial structure of the electrode sheet of the first embodiment;

[0022] Figure 2For use in this application Figure 1 A schematic diagram of the structural layout of an alternative embodiment of the electrode sheet of the first embodiment of the tumor electric field therapy system shown;

[0023] Figure 3 For this application Figure 1 The circuit connection diagram of the tumor electric field system shown illustrates... Figure 1 The electrode sheet of the first embodiment shown Figure 2 The electrode sheet of the transformation embodiment shown is Figure 1 A circuit connection diagram of the adapter of the first embodiment shown in the figure;

[0024] Figure 4 For this application Figure 3 A schematic block diagram of the internal structure of the adapter shown;

[0025] Figure 5 For this application Figure 1 A schematic block diagram of the internal structure of the electric field generator in the tumor electric field therapy system is shown.

[0026] Figure 6 and Figure 3 Similarly, a circuit connection diagram of the tumor electric field therapy system according to the second embodiment of this application is shown, illustrating the electrode sheet used in the second embodiment of the tumor electric field therapy system of this application and... Figure 3 The circuit connection diagram of the adapter is shown below;

[0027] Figure 7 and Figure 3 Similarly, a circuit connection diagram of the tumor electric field therapy system according to the third embodiment of this application is shown, illustrating the electrode plates used in the third embodiment of the tumor electric field therapy system of this application. Figure 3 The circuit connection diagram of the adapter is shown below;

[0028] Figure 8 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field therapy system according to the fourth embodiment of this application shows the electrode sheet and... Figure 3 The circuit connection diagram of the adapter is shown below;

[0029] Figure 9 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field therapy system according to the fifth embodiment of this application shows the electrode sheet and... Figure 3 The circuit connection diagram of the adapter is shown below;

[0030] Figure 10This is a schematic flowchart of the temperature detection method for the tumor electric field therapy system of this application.

[0031] Figure 11 This is a flowchart of the tumor electric field therapy system of this application;

[0032] Figure 12 This is another schematic diagram of the temperature detection method for the tumor electric field therapy system of this application;

[0033] Figure 13 A schematic flowchart illustrating the method for applying and controlling the alternating current signal for tumor electric field therapy according to this application;

[0034] Figure 14 This is a flowchart illustrating the signal control method for tumor electric field therapy according to this application;

[0035] Figure 15 This is a schematic flowchart of the electrode temperature detection method of this application;

[0036] Figure 16 This is a schematic flowchart of the method for applying alternating current signals for tumor electric field therapy according to this application.

[0037] Explanation of reference numerals in the attached figures:

[0038] Tumor electric field therapy system 100, electrode pads 10, 10', 10D, 10E, 10F, 10H, flexible circuit boards 11, 11D, 11E, 11F, 11H, connectors 111, 111', wiring parts 112, 112', bridging parts 113, 113', main trunk 114, 114', branch 115, 115', first interval D1, D1', second interval D2, D2', electrode unit 12, 12', first cable 13, 13', temperature sensor 14, grounding terminal 1 4-1, Signal terminal; 14-2, Dielectric element; 15, Diode; 16, Handshake chip; 17, Ground trace; 171, Communication line; 172, Ground wire; 18, First ground wire 18-1, Second ground wire 18-2, Third ground wire 18-3, Fourth ground wire 18-4, Dual-purpose signal line; 19, First dual-purpose signal line 19-1, Second dual-purpose signal line 19-2, Third dual-purpose signal line 19-3, Fourth dual-purpose signal line 19-4, Fifth dual-purpose signal line 19-5, Adapter; 20, Second cable; 21, ... Controller 22, Analog-to-Digital Converter 23, Voltage Divider Resistor 24, Grounding Switch 25, First Grounding Switch 25-1, Second Grounding Switch 25-2, Third Grounding Switch 25-3, Fourth Grounding Switch 25-4, Bidirectional Switch 26, First Bidirectional Switch 26-1, Second Bidirectional Switch 26-2, Third Bidirectional Switch 26-3, Fourth Bidirectional Switch 26-4, Fifth Bidirectional Switch 26-5, First Communication Unit 27, AC Signal Line 28, First Power Supply Module 29, Communication Transmission line 211, electric field generator 30, second power supply module 31, second controller 32, second communication unit 33, AC signal generator 34, AC signal switch 35, first AC signal switch 35-1, first AC signal switch 35-2, first AC signal switch 35-3, first AC signal switch 35-4, first connector 40, 40D, 40E, 40F, 40H, first plug 41, 41', first socket 42, second connector 50, second plug 51, second socket 52. Detailed Implementation

[0039] The embodiments of the technical solution of this application will now be described in detail with reference to the accompanying drawings. These embodiments are only used to more clearly illustrate the technical solution of this application and are therefore merely examples, and should not be used to limit the scope of protection of this application.

[0040] Figure 1 The diagram shown is a schematic representation of a tumor electric field therapy system 100 according to an embodiment of this application. Figure 1As shown, the tumor electric field therapy system 100 includes: at least one pair of electrode pads 10, an adapter 20 connected to the electrode pads 10, and an electric field generator 30 connected to the adapter 20. The electric field generator 30 generates an alternating current (AC) signal for tumor treatment and applies the AC signal to the electrode pads 10 via the adapter 20, thereby generating a therapeutic electric field between the paired electrode pads 10. The adapter 20 is electrically connected between the electrode pads 10 and the electric field generator 30, and is used to transmit the AC signal generated by the electric field generator 30 to the electrode pads 10. That is, the electric field generator 30 is capable of generating an AC signal, which is transmitted to each electrode pad 10 via the adapter 20, thereby generating a therapeutic electric field for treating tumors between the same pair of electrode pads 10. Figure 1 As shown, in this embodiment, there are four electrode plates 10. From a spatial arrangement perspective, each electrode plate 10 includes multiple electrode units 12 arranged in both axial and central symmetry, several connecting portions 111 located between adjacent electrode units 12, a bridging portion 113 spanning between adjacent connecting portions 111, a wiring portion 112 connected to the bridging portion 113, and a first cable 13 connected to the wiring portion 112. The bridging portion 113 and the wiring portion 112 are arranged perpendicularly, forming a "T" shape. The bridging portion 113 is spanned between adjacent connecting portions 111. Each electrode unit 12 of the electrode plate 10 is electrically connected to the adapter 20 via a first cable 13 with 10 core wires.

[0041] Each electrode unit 12 includes a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature of the area where the electrode unit 12 is applied to the patient's body surface. It can be a thermistor or other temperature sensor, and can be located at any position on the electrode unit 12. The dielectric element 15 is used to apply an alternating current signal to the tumor site on the patient. The dielectric element 15 can be a dielectric ceramic sheet or a polymer dielectric layer made of polymer material. In this embodiment, each dielectric element 15 has a through-hole (not labeled) in the middle to accommodate a corresponding temperature sensor 14. Each electrode unit 12 may also include a diode 16 connected in series with the temperature sensor 14 to prevent reverse current flow and prevent detection signals from other electrode units 12 from affecting the temperature sensor 14. The ground terminal 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16 and grounded through the cathode of the diode 16.

[0042] In the first mode, electrode unit 12 applies an alternating current signal through dielectric element 15; in the second mode, it detects or acquires the temperature of the patient's body surface to which the corresponding electrode unit 12 is applied through temperature sensor 14; in the third mode, it stops applying the alternating current signal and stops temperature detection and acquisition. The first, second, and third modes do not overlap in time periods. That is, the time period during which the dielectric element 15 of electrode unit 12 applies the alternating current signal is staggered and does not overlap with the time period during which the temperature sensor 14 detects the temperature. Electrode unit 12 can cycle between applying the alternating current signal through its dielectric element 15 and detecting the temperature through its temperature sensor 14, i.e., electrode unit 12 can cycle between the first and second modes. Electrode unit 12 can also cycle between the first, second, and third modes, i.e., electrode unit 12 cycles between applying the alternating current signal through dielectric element 15, acquiring or detecting the temperature through temperature sensor 14, stopping the application of the alternating current signal, and acquiring the temperature.

[0043] Each electrode sheet 10 includes an electrode array (unlabeled) consisting of 20 electrode units 12. The electrode array (unlabeled) also has a flexible circuit board 11 including a connecting part 111, a wiring part 112, and a bridging part 113. The 20 electrode units 12 are distributed in a spaced-out manner in an electrode array (unlabeled) arranged in four rows and six columns. Specifically, the first and last rows each have four electrode units 12, the middle two rows each have six electrode units 12, the four electrode units 12 in the first row are located in the second to fifth columns, the six electrode units 12 in each of the middle two rows are located in the first to sixth columns, and the four electrode units 12 in the last row are also located in the second to fifth columns. The connecting portion 111 is located only between adjacent electrode units 12 arranged in the column direction in the third and fourth columns, and between adjacent electrode units 12 arranged in the row direction in each row, except for the two electrode units 12 located in the third and fourth columns of each row. That is, the two adjacent electrode units 12 in the third and fourth columns are only connected by the connecting portion 111 in the column direction, and are disconnected and not connected by the connecting portion 111 in the row direction. The electrode units 12 in the first, second, fifth, and sixth columns are only connected to the electrode units 12 adjacent to them in the row direction by the horizontally arranged connecting portion 111, and are disconnected in the column direction and between them and the adjacent electrode units 12. In other words, the two adjacent electrode units 12 in the column direction in the first, second, fifth, and sixth columns are all disconnected.

[0044] The electrode units 12 in the third column and the connecting portions 111 arranged longitudinally between the electrode units 12 in that column, as well as the electrode units 12 in the fourth column and the connecting portions 111 arranged longitudinally between the electrode units 12 in that column, all constitute the main trunk 114 of the electrode array (unlabeled). The connecting portions 111 located on opposite sides of the electrode units 12 in the third and fourth columns and connected to the electrode units 12 in the third and fourth columns respectively via transversely arranged connecting portions 111, and the electrode units 12 connected to the transversely arranged connecting portions 111, all constitute the branches 115 of the electrode array (unlabeled). That is, in this embodiment, the electrode array (unlabeled) includes two main trunks 114 and several branches 115 extending laterally from the two main trunks 114. Each branch 115 has a free end away from the main trunk 114, and the free ends of adjacent branches 115 are disconnected. The position and distance between adjacent branches 115 can be freely adjusted according to actual usage requirements. Specifically, one main branch 114 is composed of each electrode unit 12 located in the third column and a connecting portion 111 arranged longitudinally between adjacent electrode units 12 in that column. The other main branch 114 is composed of each electrode unit 12 located in the fourth column and a connecting portion 111 arranged longitudinally between adjacent electrode units 12 in that column. The remaining electrode units 12 connected to the main branches 114 via the transversely arranged connecting portions 111 are all branches 115.

[0045] Specifically, the branches 115 are: a connecting portion 111 extending laterally to the left from the electrode unit 12 in the first row of the third column and located in the first row, and an electrode unit 12 connected to the connecting portion 111 and located in the second column of the first row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the second row of the third column and located in the second row, and two electrode units 12 located in the first column and second column of the second row; two connecting portions 111 extending laterally to the left from the electrode unit 12 in the third row and located in the third row, and two electrode units 12 located in the first column and second column of the third row; a connecting portion 111 extending laterally to the left from the electrode unit 12 in the fourth row and located in the fourth row, and two electrode units 12 located in the first column and second column of the third row; The electrode unit 12 in the second column of the fourth row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the first row of the fourth row and located in the first row and an electrode unit 12 in the fifth column of the first row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the second row of the fourth row and located in the second row and two electrode units 12 located in the fifth and sixth columns of the second row; two connecting portions 111 extending laterally to the right from the electrode unit 12 in the third row of the fourth row and located in the third row and two electrode units 12 located in the fifth and sixth columns of the third row; a connecting portion 111 extending laterally to the right from the electrode unit 12 in the fourth row and located in the fourth row and an electrode unit 12 located in the fifth column of the fourth row.

[0046] The electrode array (unlabeled) is divided into a symmetrical left portion comprising three columns on the left and a right portion comprising three columns on the right, connected only by a bridging section 113. The left portion consists of a main stem 114 located in the third column and several branches 115 extending laterally to the left from this main stem 114. The right portion consists of a main stem 114 located in the fourth column and several branches 115 extending laterally to the right from this main stem 115. The two main stems 114 are connected by a bridging section 113. Specifically, the two main stems 114 are electrically connected by a bridging section 113 located between the connecting sections 111 of the electrode units 12 in the second row of the third column and the connecting sections 111 of the electrode units 12 in the second row of the fourth column and the connecting sections 111 of the electrode units 12 in the third row of the fourth column. The connecting portion 111 connecting the electrode unit 12 in the second row of the third column to the electrode unit 12 in the third row of the third column, the connecting portion 111 connecting the electrode unit 12 in the second row of the fourth column to the electrode unit 12 in the third row of the fourth column, and the bridging portion 113 are generally arranged in an "H" shape. In other embodiments, the bridging portion 113 may also be provided between an electrode unit 112 located in the third column and an electrode unit 12 located in the fourth column. Optionally, the bridging portion 113 is provided between two electrode units 12 located in the third and fourth columns and adjacent in the row direction.

[0047] Each electrode unit 12, according to its position in the electrode array (unlabeled), can be divided into peripheral electrode units 12 and central electrode units 12. The peripheral electrode units 12 include four electrode units 12 in the first row, two electrode units 12 at opposite ends of the second row, two electrode units 12 at opposite ends of the third row, and four electrode units 12 in the fourth row. The central electrode units 12 include four electrode units 12 in the middle of the second row and four electrode units 12 in the middle of the third row. Some adjacent electrode units 12 in the peripheral array are connected by horizontally arranged connecting portions 111, while some adjacent electrode units 12 are disconnected. The adjacent electrode units 12 connected by connecting portions 111 in the peripheral array are some row-adjacent electrode units 12. Specifically, among the multiple electrode units 12 located on the periphery, two electrode units 12 that are adjacent in a column direction or diagonally adjacent are disconnected; two electrode units 12 that are partially adjacent in a row direction are also disconnected; only two electrode units 12 that are partially adjacent in a row direction are connected by a laterally extending connecting portion 111. Among the multiple electrode units 12 located in the center, only two electrode units 12 that are adjacent in a column direction on the main trunk 114 are connected by a longitudinally arranged connecting portion 111, and only two electrode units 12 that are adjacent in a row direction on the branch 115 are connected by a laterally arranged connecting portion 111.

[0048] The electrode array (unlabeled) also has gaps (unlabeled) formed between several spaced electrode units 12, allowing moisture to escape from the patient's skin, heat exchange between the patient's skin and the outside environment, or free breathing of the patient's skin. It also allows for free adjustment of the position and spacing between the branches 115 and prevents wrinkling of the electrode pads 10 during application. The gaps (unlabeled) include a first gap D1 located between the two main branches 114 and a second gap D2 located between the branches 115. The first gap D1 is located between the third and fourth columns of electrode units 12, while the second gap D2 is located between adjacent rows of electrode units 12. That is, along the row upwards, the electrode unit 12 located in the third column is disconnected from the adjacent electrode unit 12 located in the fourth column, and no connecting part 111 is provided for either of them, but instead forms the aforementioned first interval D1; and along the column upwards, only the two adjacent electrode units 12 in the third and fourth columns are connected by the connecting part 111, while the two adjacent electrode units 12 in the other four columns are not connected by the connecting part 111, but instead form the aforementioned second interval D2. The setting of the first and second intervals D1 and D2 can also increase the degree of freedom of some electrode units 12, and can also avoid wrinkles when attaching the electrode sheet 10.

[0049] The electrode pad 10 also includes a handshake chip 17 disposed on the flexible circuit board 11 for confirming its connection status. The handshake chip 17 can communicate with the electric field generator 30 via the adapter 20 to determine the connection status between the electrode pad 10 and the adapter 20. The electric field generator 30 of the tumor electric field therapy system 100 first sends a handshake communication signal to the handshake chip 17 of the electrode pad 10 via the adapter 20, and determines the connection status of the electrode pad 10 based on whether it receives feedback from the handshake chip 17. After confirming that the electrode pad 10 is properly connected via the handshake chip 17, the electric field generator 30 of the tumor electric field therapy system 100 applies an AC signal to the dielectric element 15 of the electrode pad 10 or transmits a DC signal to each temperature sensor 14 of the electrode pad 10 to acquire temperature detection signals. The handshake chip 17 can be an EEPROM with encryption function.

[0050] In other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode pads 10. In other embodiments, each pair of electrode pads 10 may have the same or different numbers of electrode units 12, and different pairs of electrode pads 10 may also have different numbers of electrode units 12. In other embodiments, the 20 electrode units 12 may also be arranged in other ways. Of course, in other embodiments, the electrode pads 10 may also have other numbers of electrode units 12. In other embodiments, the 20 electrode units 12 may also be arranged in other ways, such as... Figure 2 The electrode sheet 10' is shown. Of course, in some other embodiments, the electrode sheet 10 may also have other numbers of electrode units 12. In summary, the implementation of this application is not limited by the number and arrangement of the electrode units 12 of the electrode sheet 10.

[0051] Figure 2 The electrode plate 10' shown is Figure 1In a modified embodiment of the electrode sheet 10 shown, the spatial structure of the electrode sheet 10' is the same as that of the electrode sheet 10, and it also includes a plurality of electrode units 12' arranged at intervals, a plurality of connecting portions 111' located between adjacent electrode units 12', a wiring portion 112' connected to a bridging portion 113', a first cable 13' connected to the wiring portion 112', a first interval D1 formed between the third column of electrode units 12' and the fourth column of electrode units 12', and a second interval D2' formed between adjacent rows of electrode units 12'; the connecting portions 111', the wiring portions 112', and the bridging portions 113' also constitute a flexible circuit board (not labeled), and the electrode sheet 10' is also connected to adapter 20 via a first plug 41' of a first cable 13' with 10 core wires. The only difference is that: in the fourth column, two adjacent electrode units 12' are disconnected and not connected by a longitudinally arranged connecting part 111', but in the fifth column, two adjacent electrode units 12' are connected by a longitudinally arranged connecting part 111'. Each electrode unit 12' in the fourth column is connected to an adjacent electrode unit 12' in the fifth column via a transversely arranged connecting part 111'. Furthermore, a bridging part 113' connects the two electrode units 12' located in the third row and third column of the third row and the two electrode units 12' located in the fourth row. One main branch 114' is composed of an electrode unit 12' located in the third column and a connecting part 111' located between the electrode units 12' in that column, and another main branch 114' is composed of an electrode unit 12' located in the fifth column and a connecting part 111' located between the electrode units 12' in that column. The structure of the left portion of the left three columns of the electrode array (unlabeled) is similar to... Figure 1 The left side of the electrode array (unlabeled) shown is completely identical in structure. Only the right side is different because the position of the main trunk 114' changes from the fourth column to the fifth column, resulting in the branches 115' in the right side extending to the left and right sides of the corresponding electrode units 12' in the main trunk 114' respectively.

[0052] Figure 3 for Figure 1 The electrode pad 10 shown in the first embodiment of the tumor electric field therapy system 100 or Figure 2 The diagram shows the circuit connection between the electrode plate 10' of the transformation embodiment and the adapter 20 of the first embodiment. It is worth noting that: Figure 3 The arrangement of the electrode units 12 shown is to more clearly illustrate the electrical connection between an electrode plate 10 and the adapter 20. Figure 3 The arrangement of electrode units 12 shown does not represent the spatial arrangement of electrode units 12. The circuit connection is described below using the electrode sheet 10 in the first embodiment as an example.

[0053] Combination Figure 1 as well as Figure 3In this embodiment, each electrode sheet 10 has 20 electrode units 12. These 20 electrode units 12 are grouped in the order of 1 to 20 in the circuit connection, forming four row groups and five column groups, i.e., the 20 electrode units 12 are arranged in a four-row, five-column configuration in the circuit connection. Each electrode unit 12's temperature sensor 14 includes a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and temperature sensor 14 of each electrode unit 12 are soldered onto the flexible circuit board 11, and the dielectric element 15 is short-circuited to the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in a four-row, five-column configuration in the circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, the multiple temperature sensors 14 are also arranged in a four-row, five-column configuration in the circuit connection, and the multiple dielectric elements 15 are also arranged in a four-row, five-column configuration in the circuit connection. It should be noted that the arrangement shown here is to more clearly illustrate the electrical connection between the electrode plate 10 and the adapter 20, and does not represent the spatial arrangement of the electrode unit 12. Its spatial structure may be as follows: Figure 1 The structure shown is generally array-like, but it can also be other structures, such as petal-shaped or scattering-shaped, and can be regular or irregular. The dielectric element 15 is configured to apply an alternating electric field to the patient's tumor site. The temperature sensor 14 is configured to detect the temperature of the patient's body surface in contact with the electrode pads 10 and output a temperature detection signal to the adapter 20.

[0054] The flexible circuit board 11 is embedded with multiple conductive traces 171, 172, 18, and 19. These traces include multiple ground lines 18, multiple dual-purpose signal lines 19, one ground trace 171, and one communication line 172. One end of the ground trace 171 is connected to the ground pin of the handshake chip 17, and the other end is connected to any one of the ground lines 18. The ground pin of the handshake chip 17 is connected to the ground trace 171, and its communication pin is electrically connected to the communication line 172. That is, the handshake chip 17 is grounded through the ground line 18 connected to the ground trace 171, and communicates with external devices through the communication line 172. Specifically, the handshake chip 17 is grounded via a ground trace 171 connected to its ground pin and a ground line 18. It then sequentially connects to the communication line 172 of the flexible circuit board 11, a wire electrically connected to the first cable 13 and the communication line 172, an adapter 20 electrically connected to the first cable 13, and an electric field generator 30 electrically connected to the adapter 20, thereby determining the connection status of the electrode plate 10. The first cable 13 has multi-core wires (not shown) electrically connected to the communication line 172, the multiple ground lines 18, and the multiple dual-purpose signal lines 19 of the flexible circuit board 11, respectively. The total number of communication lines 172, ground lines 18, and dual-purpose signal lines 19 embedded in the flexible circuit board 11 does not exceed 10. Therefore, the number of wires in the first cable 13 does not exceed 11.

[0055] The number of conductive lines electrically connected to the grounding wire 18 in the tumor electric field therapy system 100 is related to the number of rows M of the electrode unit 12, which can be greater than or equal to the number of rows M of the electrode unit 12, where M is a positive integer. The number of conductive lines electrically connected to the dual-purpose signal line 19 in the tumor electric field therapy system 100 is related to the number of columns N of the electrode unit 12, which can be greater than or equal to the number of columns N of the electrode unit 12, where N is a positive integer. In this embodiment, the number of grounding wires 18 is equal to the number of rows M of the electrode unit 12; the number of dual-purpose signal lines 19 is equal to the number of columns N of the electrode unit 12. The number of lines L embedded in the flexible circuit board 11 is equal to the sum of the number of grounding wires 18 and the number of dual-purpose signal lines 19 plus 2, that is, L = M + N + 2. The number of conductors in the first cable 13 is M + N + 1.

[0056] The flexible circuit board 11 has multiple dual-purpose signal lines 19 corresponding to multiple columns of electrode units 12, configured to transmit the AC signal generated by the electric field generator 30 to the dielectric element 15 in each electrode unit 12 of the corresponding column. Specifically, dielectric elements 15 in the same column are short-circuited via the same dual-purpose signal line 19 of the flexible circuit board 11, while dielectric elements 15 in different columns are connected in parallel via different dual-purpose signal lines 19 of the flexible circuit board 11. The dual-purpose signal lines 19 of the flexible circuit board 11 are electrically connected to corresponding wires in the first cable 13, and then electrically connected to the electric field generator 30 via the adapter 20. In other words, the dual-purpose signal lines 19 of the flexible circuit board 11 receive the AC signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.

[0057] Multiple grounding lines 18 are respectively configured to correspond one-to-one with multiple rows of electrode units 12. Each grounding line 18 is used to sequentially short-circuit and ground the temperature sensor 14 of each electrode unit 12 in each row. That is, the grounding terminals 14-1 of multiple temperature sensors 14 located in the same row are all short-circuited through the same grounding line 18 of the flexible circuit board 11, and the grounding terminals 14-1 of temperature sensors 14 located in different row groups are connected in parallel through different grounding lines 18 of the flexible circuit board 11. During the temperature detection period or in the second mode, only one of the multiple grounding lines 18 is conductive at any given time, while the others are disconnected.

[0058] Each of the multiple dual-purpose signal lines 19 is also configured to transmit a DC signal to the temperature sensor 14 in each electrode unit 12 of the corresponding column group to collect and transmit the detected temperature signal. The signal terminals 14-2 of multiple temperature sensors 14 located in different column groups are connected in parallel via different dual-purpose signal lines 19 of the flexible circuit board 11. The signal terminals 14-2 of multiple temperature sensors 14 located in the same column group are all short-circuited to the same dual-purpose signal line 19 of the flexible circuit board 11, and the short-circuit point serves as a temperature sampling point. Specifically, each dual-purpose signal line 19 is configured to short-circuit the signal terminal 14-2 of at most one temperature sensor 14 in each row group to an external device for receiving the detection signal. The signal terminals 14-2 of the temperature sensors 14 connected to each of the multiple dual-purpose signal lines 19 are different to avoid duplicate signals output by the dual-purpose signal line 19. That is, when the number of electrode units 12 in a row group is the same as the number of dual-purpose signal lines 19, each dual-purpose signal line 19 is electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different electrode unit 12 in that row group; when the number of electrode units 12 in a row group is less than the number of dual-purpose signal lines 19, at least one dual-purpose signal line 19 is not electrically connected to the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12, and the remaining dual-purpose signal lines 19 are electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different electrode unit 12 in that row group. In this embodiment, the external device for receiving the detection signal is an adapter 20. The dual-purpose signal lines 19 of the flexible circuit board 11 receive DC signals from the adapter 20 or the electric field generator 30 through the first cable 13, and transmit the collected or detected temperature signals to the adapter 20, and then to the electric field generator 30 via the adapter 20.

[0059] In this embodiment, with each electrode unit 12 equipped with a temperature sensor 14 for temperature detection, the above-mentioned circuit design reduces the number of wires in the first cable 13, avoiding the cable from becoming thicker and harder, thus increasing the difficulty of cable fixation; at the same time, it avoids the increased number of wires in the first cable 13 affecting the adhesion effect between the electrode sheet 10 and the corresponding body surface of the patient's tumor site.

[0060] The flexible circuit board 11 has a total of 9 embedded grounding wires 18 and dual-purpose signal lines 19. In this embodiment, the flexible circuit board 11 has 4 embedded grounding wires 18 and 5 embedded dual-purpose signal lines 19. Specifically, the electrode sheet 10 in this embodiment includes 4 grounding wires 18, each grounding wire 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 in the same row group. The 4 grounding wires 18 of the electrode sheet 10 are the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4. In the 4 rows of the electrode sheet 10, the first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-20. Specifically, the first grounding wire 18-1 is used to ground electrode units 12-1 to 12-5 in the first row group; the second grounding wire 18-2 is used to ground electrode units 12-6 to 12-10 in the second row group; the third grounding wire 18-3 is used to ground electrode units 12-11 to 12-15 in the third row group; and the fourth grounding wire 18-4 is used to ground electrode units 12-16 to 12-20 in the fourth row group. It should be noted that these grounding wires 18 can be selectively closed or opened, which can be achieved by connecting each grounding wire 18 in series with a switch, as will be described in detail below. The phrase "grounding electrode unit 12" can refer to grounding the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12, or it can refer to the diode 16 being connected in series with the temperature sensor 14 in the same electrode unit 12 and grounded together. In short, each grounding wire 18 shorts and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group. The fourth grounding wire 18-4 is also shorted to the grounding trace 171 connected to the grounding pin of the handshake chip 17.

[0061] Continue to refer to Figure 3As shown, the electrode sheet 10 in this embodiment also includes five dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 12 in each row group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting AC signals. That is, for each row group, each dual-purpose signal line 19 can be selectively connected to one of the electrode units 12 or not connected to any of the electrode units 12 in that row group to avoid subsequent repetitive signal output from the dual-purpose signal line 19. Specifically, the five dual-purpose signal lines 19 of the electrode sheet 10 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-6, 12-11, and 12-16) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-2, 12-7, 12-12, and 12-17) and the signal terminal 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to electrode units 12-3, 12-8, and 12-1... 3. Each of the four electrode units 12 (12-18) has its own dielectric element 15 and its own temperature sensor 14 signal terminal 14-2. One end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of the four electrode units 12 (12-4, 12-9, 12-14, and 12-19). One end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 and the signal terminal 14-2 of the four electrode units 12 (12-5, 12-10, 12-15, and 12-20). In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 located in the same column group and uses them to connect to external devices. It should be noted that these dual-purpose signal lines 19 can selectively transmit AC signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switching switch 26 and coordinating with the closing or opening of the grounding wire 18, which will be described in detail below.

[0062] In other embodiments, the number of grounding wires 18 and dual-purpose signal lines 19 embedded in the flexible circuit board 11 may vary depending on the circuit arrangement and number of electrode units 12 in different electrode sheets, which will be described in detail in subsequent embodiments.

[0063] In this embodiment, the electrode plate 10 is used to confirm the connection status of the handshake chip 17. The ground pin is connected to the fourth ground line 18-4 through the ground trace 171 embedded on the flexible circuit board 11. The first cable 13 has 10 cores, namely 4 ground lines 18, 5 dual-purpose signal lines 19, and 1 communication line 172. The specific connection relationship and working principle of the handshake chip 17 will be described in detail below.

[0064] The tumor electric field therapy system 100 of this embodiment includes at least one pair of electrode pads 10 as described above, an adapter 20 electrically connected to the electrode pads 10, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode pads 10 and the electric field generator 30. When the electric field generator 30 or the adapter 20 controls the grounding pin of the handshake chip 17 to be grounded, the electric field generator 30 sends a handshake communication signal to the handshake chip 17 of the electrode pads 10 via the communication line 172 of the adapter 20 and the electrode pads 10 to determine the connection status of the electrode pads 10. When the electrode plates 10 are properly connected, the electric field generator 30 provides AC signals to the dielectric elements 15 in the multiple electrode units 12 of the electrode plate 10 via the adapter 20 and the dual-purpose signal line 19 of the electrode plate 10, or provides DC signals to the temperature sensors 14 in the multiple electrode units 12 of the electrode plate 10 via the adapter 20 and the dual-purpose signal line 19 of the electrode plate 10, and is used to receive temperature detection signals output by the temperature sensors 14 in the multiple electrode units 12. The adapter 20 is configured to send a handshake communication signal to the communication line 172 of the electrode plate 10 according to the communication command of the electric field generator 30, and is configured to transmit the AC signals generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode plate 10, and is also configured to transmit DC signals to the dual-purpose signal line 19 of the electrode plate and receive temperature detection signals output by the multiple dual-purpose signal line 19 of the electrode plate 10.

[0065] Continue to refer to Figure 3 and Figure 4As shown, the adapter 20 includes: a first controller 22, a multi-channel communication transmission line 211 electrically connected to the first controller 22, multiple sets of analog-to-digital converters 23 connected to the first controller 22, multiple sets of voltage-reducing resistors 24 corresponding to each set of analog-to-digital converters 23, multiple sets of grounding switches 25, multiple sets of bidirectional switching switches 26 corresponding to each set of analog-to-digital converters 23, a first communication unit 27, AC signal lines 28 corresponding to each set of bidirectional switching switches 26, and a first power module 29 simultaneously connected to the first communication unit 27, the first controller 22, and the multiple sets of analog-to-digital converters 23. The first power module 29 provides DC power VCC to each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unlabeled). Among them, the multiple circuit lines (unlabeled) are electrically connected to the multiple grounding lines 18, multiple dual-purpose signal lines 19, and communication lines 172 in the flexible circuit board 11 of the corresponding electrode plates 10 through the first cables 13 of the corresponding electrode plates 10. The multiple circuit lines (unlabeled) include multiple AC signal lines 28 that transmit AC signals to the corresponding electrode 10 and are electrically connected to the multi-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10; multiple circuit lines (unlabeled) that are electrically connected one-to-one with the multi-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode 10 and are used to power the temperature sensors 14 of the electrode 10 or transmit the temperature detection signals of the electrode 10; multiple circuit lines (unlabeled) that are electrically connected one-to-one with the grounding lines 18 in the flexible circuit board 11 of the corresponding electrode 10; and multiple communication transmission lines 211 that are electrically connected one-to-one with the communication lines 172 in the flexible circuit board 11 of the corresponding electrode 10. All communication transmission lines 211 are connected to the first controller 22. Each communication transmission line 211 is connected to the communication line 172 of the flexible circuit board 11 through the corresponding first connector 40, and the first controller 22 and the handshake chip 17 are electrically connected by the grounding switch 25 corresponding to the grounding line 18 short-circuited by the grounding pin of the handshake chip 17 of the closed flexible circuit board 11, so that the handshake chip 17 can obtain power and enable the data communication function.

[0066] The number P of circuit lines electrically connecting adapter 20 to one electrode piece 10 is equal to the sum of the number of rows M and columns N of the electrode units 12 of electrode piece 10 plus 2; the number H of circuit lines electrically connecting adapter 20 to X electrode pieces 10 is equal to X times the number of circuit lines electrically connecting it to a single electrode piece 10, that is... The number of grounding switches 25, the number of bidirectional switching switches 26, the number of AC lines 28, and the number of communication transmission lines 211 are all related to the number of electrode plates 10. The number of grounding switches 25, the number of bidirectional switching switches 26, the number of AC lines 28, and the number of communication transmission lines 211 are all the same; and not less than the number of electrode plates 10. Preferably, the number of grounding switches 25, the number of bidirectional switching switches 26, the number of AC lines 28, and the number of communication transmission lines 211 are all the same as the number of electrode plates 10. The following detailed description only uses the electrical connection between an electrode plate 10 with 20 electrode units 12 and the adapter 20 as an example.

[0067] Each group of grounding switches 25 has multiple grounding switches 25, which are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding wires 18 of a corresponding electrode piece 10, and are configured to control the conduction or disconnection of the multiple grounding wires 18. The circuit lines (unlabeled) that are each electrically connected to the multiple grounding wires 18 of the electrode piece 10 are grounded at the end closest to the grounding switch 25. The number of grounding switches 25 in each group of grounding switches 25 is related to the number of grounding wires 18 of the flexible circuit board 11 of the corresponding electrode piece 10; in this embodiment, the two are equal. Figure 3As shown, in this embodiment, each group of grounding switches 25 includes a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3, and a fourth grounding switch 25-4. Each of the multiple grounding switches 25 in each group controls the closing or opening of the corresponding grounding wire 18 of a corresponding electrode plate 10. Specifically, the first grounding switch 25-1 is used to control the opening or closing of the first grounding wire 18-1 of the corresponding electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row of the electrode plate 10; the second grounding switch 25-2 is used to control the opening or closing of the second grounding wire 18-2 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of each temperature sensor 14 of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the second row of the electrode plate 10; the third grounding switch 25-3 is used to control the third grounding wire 18-1 of the electrode plate 10. The closing or opening of ground wire 18-3, in conjunction with the corresponding set of bidirectional switching switches 26, controls the energization and de-energization of the temperature sensors 14 of the five electrode units 12 (12-11 to 12-15) in the third row of the electrode plate 10. The fourth grounding switch 25-4 controls the closing or opening of the fourth grounding wire 18-4 of the electrode plate 10, thereby determining the connection status of the electrode plate 10 through the electrical connection status between the communication line 172 of the handshake chip 17 and the communication transmission line 211 of the adapter 20. It can also cooperate with the corresponding set of bidirectional switching switches 26 to control the energization and de-energization of the temperature sensors 14 of the five electrode units 12 (12-16 to 12-20) in the fourth row of the electrode plate 10. The grounding switch 25 can be a mechanical switch, such as a relay. The grounding switch 25 can also be an electronic switch, and each grounding switch 25 can be opened and closed by the first controller 22 of the adapter 20.

[0068] In this embodiment, all sets of grounding switches 25 are electronic switches. The first controller 22 is communicatively connected to the multiple sets of grounding switches 25 and is used to sequentially and cyclically control the opening and closing states of multiple grounding switches 25 in each set, thereby sequentially and individually activating each of the multiple grounding wires 18 of the corresponding electrode pad 10 and coordinating with the switching of the corresponding bidirectional switching switch 26 to sequentially and time-divisionally collect the patient's body surface temperature detected by all temperature sensors 14 on the electrode pad 10. The number of grounding switches 25 in each set is greater than or equal to the number of grounding wires 18 on the flexible circuit board 11 of the corresponding electrode pad 10. In this embodiment, the number of grounding switches 25 in each set is the same as the number of grounding wires 18 on the corresponding electrode pad 10.

[0069] Each group of bidirectional switching switches 26 has multiple bidirectional switching switches 26. The multiple bidirectional switching switches 26 in each group are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multi-purpose signal lines 19 of a corresponding electrode piece 10. The number of bidirectional switching switches 26 in each group is related to the number of dual-purpose signal lines 19 on the flexible circuit board 11 of the corresponding electrode piece 10, and is greater than or equal to the number of dual-purpose signal lines 19 on the flexible circuit board 11 of the corresponding electrode piece 10. Figure 3 In the illustrated embodiment, both are equal. Each bidirectional switch 26 has a sampling terminal 1 and an input terminal 2. The sampling terminals 1 of multiple bidirectional switches 26 in the same group are electrically connected one-to-one with the corresponding detection channels of multiple detection channels of a corresponding group of analog-to-digital converters 23. Each detection channel corresponds one-to-one with a corresponding temperature sampling point. The input terminal 2 of each bidirectional switch 26 in the same group is electrically connected to the corresponding AC signal line 28. Each bidirectional switch 26 is configured to control the multiplexer signal line 19 to connect to the corresponding AC signal line 28 to transmit AC signals or to connect to the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.

[0070] like Figure 3 As shown, taking the electrical connection of one electrode plate 10 with the adapter 20 as an example, in this embodiment with 20 electrode units 12, the multiple bidirectional switching switches 26 are respectively the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5. The multiple bidirectional switching switches 26 in the same group each control the switching of a corresponding dual-purpose signal line 19 in the multi-channel dual-purpose signal line 19 of the same electrode plate 10 between transmitting AC power signals and transmitting temperature detection signals.

[0071] Specifically, the first bidirectional switching switch 26-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each dielectric element 15 of the electrode units 12-1, 12-6, 12-11, and 12-16 in the first column of the electrode 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 in the first column of the electrode units 12-1, 12-6, 12-11, and 12-16, and the corresponding first grounding switch 25-1, second grounding switch 25-2, and the first... The three grounding switches 25-3 and 25-4 work together to enable the first row of electrode units 12-1, 12-6, 12-11, and 12-16 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the second bidirectional switch 26-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals, thereby controlling the electrode units 12-2, 12-7, 12-12, and 12-17 in the second row of the electrode pad 10. The switching between the conduction of each dielectric element 15 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of the electrode units 12-2, 12-7, 12-12, and 12-17 in the second column group, and in conjunction with the corresponding grounding switches 25-1, 25-2, 25-3, and 25-4, enables the second column of electrode units 12-2, 12-7, 12-12, and 12-17 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23;The third bidirectional switching switch 26-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode pad 10 between transmitting AC signals and transmitting temperature detection signals. This controls the switching between the conduction of the dielectric elements 15 of each electrode unit 12-3, 12-8, 12-13, and 12-18 in the third column of the electrode pad 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 in the third column of the electrode unit 12-3, 12-8, 12-13, and 12-18. It also cooperates with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4 to enable the third column of electrode units 12-3, 12-8, 12-13, and 12-18 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. The fourth bidirectional switching switch 26-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode 10 between transmitting AC signals and transmitting temperature detection signals. This controls the switching between the conduction of the dielectric elements 15 of each electrode unit 12-4, electrode unit 12-9, electrode unit 12-14, and electrode unit 12-19 in the fourth column of the electrode 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of each electrode unit 12-4, electrode unit 12-9, electrode unit 12-14, and electrode unit 12-19 in the fourth column. It also cooperates with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4 to enable the fourth column of electrode units 12-4, electrode unit 12-9, electrode unit 12-14, and electrode unit 12-19 to transmit AC signals to the patient or output temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23.The fifth bidirectional switching switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode 10 between transmitting AC signals and transmitting temperature detection signals. This controls the switching between the conduction of the dielectric elements 15 of each electrode unit 12-5, electrode unit 12-10, electrode unit 12-15, and electrode unit 12-20 in the fifth column of the electrode 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of each electrode unit 12-5, electrode unit 12-10, electrode unit 12-15, and electrode unit 12-20. It also cooperates with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4 to enable the fifth column of electrode units 12-5, electrode unit 12-10, electrode unit 12-15, and electrode unit 12-20 to transmit AC signals to the patient or output the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. ;

[0072] When all grounding switches 25 are open and the input terminal 2 of each bidirectional switching switch 26 is on while the sampling terminal 1 is off, AC signals can be transmitted to the dielectric elements 15 of each electrode unit 12 of the corresponding electrode plate 10. When the sampling terminal 1 of each bidirectional switching switch 26 is on while the input terminal 2 is off, it can cooperate with each grounding switch 25 in the corresponding group of grounding switches 25 to transmit the temperature detection signals collected by the temperature sensors 14 of each electrode unit 12 on the electrode plate 10 in a time-division manner. The bidirectional switching switch 26 can be a mechanical switch, such as a relay. The bidirectional switching switch 26 can also be an electronic switch, and the switching between the sampling terminal 1 and the input terminal 2 of each bidirectional switching switch 26 can be controlled by the first controller 22 of the adapter 20.

[0073] In this embodiment, all sets of bidirectional switching switches 26 are electronic switches. The first controller 22 is communicatively connected to the multiple sets of bidirectional switching switches 26, controlling the switching of each set of bidirectional switching switches 26 between its respective sampling terminal 1 and input terminal 2, and coordinating with the closing or opening of the corresponding grounding switch 25, to continuously monitor the patient's body surface temperature detected by all temperature sensors 14 on the electrode pad 10 or to transmit AC signals to the patient. In this embodiment, the multiple sets of grounding switches 25 and the multiple sets of bidirectional switching switches 26 together form a switching unit (not labeled).

[0074] In this embodiment, each group of analog-to-digital converters 23 is electrically connected one-to-one to the sampling terminals 1 of multiple bidirectional switching switches 26 in the corresponding group through multiple circuit lines (unlabeled) within the adapter 20, and is configured to receive temperature detection signals transmitted from the multi-purpose signal lines 19 of the corresponding electrode sheet 10, and convert the temperature detection signals from analog signals to digital signals. Each group of analog-to-digital converters 23 includes multiple detection channels A, B, C, D, and E, each detection channel A, B, C, D, and E is used to connect to one corresponding multi-purpose signal line 19 in the multi-purpose signal lines 19 through the corresponding bidirectional switching switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switching switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of electrode units 12 of the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26, and is not less than the number of column groups of electrode units 12 in the corresponding electrode sheet 10. For example... Figure 3 As shown, each group of analog-to-digital converters 23 includes five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 through the sampling terminal 1 of the first bidirectional switch 26-1; the second detection channel B is connected to the second dual-purpose signal line 19-2 through the sampling terminal 1 of the second bidirectional switch 26-2; the third detection channel C is connected to the third dual-purpose signal line 19-3 through the sampling terminal 1 of the third bidirectional switch 26-3; the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through the sampling terminal 1 of the fourth bidirectional switch 26-4; and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 through the sampling terminal 1 of the fifth bidirectional switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, and E is connected to a first power supply module 29 via a corresponding voltage divider resistor 24 in the adapter 20. The first power supply module 29 provides a DC signal.

[0075] In this embodiment, the first communication unit 27 is configured to acquire digital signals output by multiple sets of analog-to-digital converters 23 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage, current, or power of the AC signal provided to the multiple electrode units 12 of the electrode sheet 10 according to the received digital signals. For example, when any of the received digital signals exceeds a preset threshold, it indicates that the temperature detected by at least one temperature sensor 14 in the electrode sheet 10 at the corresponding dielectric element 15 applied to the human body surface exceeds the preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage, current, or power of the AC signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode units 12 of the electrode sheet 10 becoming too hot when the AC signal is applied, causing low-temperature burns to the patient's skin. The aforementioned preset threshold temperature and preset threshold can be determined according to human safety thresholds. The first communication unit 27 is controlled by the first controller 22 and serially transmits the digital signals converted by the multiple sets of analog-to-digital converters 23. In this embodiment, the preset temperature threshold can be a value within the range of 36℃-45℃.

[0076] Each of the multiple communication transmission lines 211 embedded in the adapter 20 has one end connected to the first controller 22, and the other end electrically connected to a communication line 172 that is electrically connected to the communication pin of the handshake chip 17 of the corresponding electrode 10 through the corresponding wire of the corresponding first cable 13. The ground pin GND of the adapter 22 is also connected to the corresponding wire of the corresponding first cable 13 through a wire electrically connected to the corresponding grounding switch 25, a grounding wire 18 that is connected to both the corresponding wire of the first cable 13 and the grounding trace 171, and the grounding trace 171 that is shorted to the grounding wire 18 to achieve the connection to the ground pin of the handshake chip 17 of the corresponding electrode 10. That is, the first controller 22 controls the grounding switch 25 corresponding to the grounding line 18-4 that is short-circuited to the grounding pin of the handshake chip 17 of the electrode 10 to close, and sends a handshake communication signal to the communication line 172 of the electrode 17 through the communication transmission line 211. The first controller 22 determines whether the connection between the electrode 10 and the adapter 20 is normal based on whether the first controller 22 can receive the feedback from the communication line 172 of the electrode 10.

[0077] refer to Figure 4 as well as Figure 5 In this embodiment, the first power module 29 is electrically connected to the second power module 31 of the electric field generator 30 and is configured to supply power to the first controller 22, multiple analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. A first connector 40 is provided between each electrode piece 10 and the adapter 20, and the first connector 40 is adapted to connect the corresponding electrode piece 10 to the adapter 20. Figure 1As shown, the first connector 40 includes a first plug 41 located at the end of the first cable 13 away from the electrode plate 10 and a first socket 42 located on the adapter 20. The first plug 41 and the first socket 42 are push-button spring connectors, that is, the first connector 40 connects the adapter 20 and the electrode plate 10 using a connector method. Each first cable 13 has 5 wires that are electrically connected to the bidirectional switching switches 26-1, 26-2, 26-3, 26-4, and 26-5 in the corresponding bidirectional switching switches 26, 4 wires that are electrically connected to the grounding switches 25-1, 25-2, 25-3, and 25-4 in the corresponding grounding switches 25, and 1 wire that is electrically connected to both the communication line 172 of the electrode plate 10 and the communication transmission line 211 of the adapter 20. That is, each first connector 40 is electrically connected to a set of bidirectional switching switches 26, a set of grounding switches 25, and a communication transmission line 211 connected to the first controller 22 via 10 wires; and is connected to the electric field generator 30 via a corresponding AC signal line 28 of the adapter 20.

[0078] A second connector 50 is provided between the adapter 20 and the electric field generator 30. The second connector 50 is adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 also includes a second cable 21 connected to the second connector 50. The second connector 50 includes a second plug 51 located at the end of the second cable 21 away from the first controller 22 and a second socket 52 located on the electric field generator 30. The second plug 51 and the second socket 52 are push-button spring connectors, that is, the second connector 50 connects the adapter 20 and the electric field generator 30 by means of a plug. Each first connector 40, such as X1, Y1, X2, and Y2, is connected to the second connector 50 via a corresponding AC signal line 28. The first connectors 40, such as X1, Y1, X2, and Y2, are respectively connected to a corresponding set of grounding switches 25, a corresponding set of analog-to-digital converters 23, and a corresponding communication transmission line 211. Each first connector 40 is connected to the second connector 50 and the corresponding set of analog-to-digital converters 23 via a corresponding set of bidirectional switching switches 26. Taking four electrode plates 10 as an example, the second cable 21 has eight wires, including four wires 1 to 4 that are electrically connected to the corresponding AC signal lines 28 for transmitting AC signals, one wire 5 that is electrically connected to the data receiving line RX of the first communication unit 27, one wire 6 that is electrically connected to the data transmitting line TX of the first communication unit 27, one wire 7 that is electrically connected to the VCC power line of the first power module 29, and one wire 8 that is electrically connected to the GND line of the first power module 29. The second connector 50 is connected to the first communication unit 27 via a data receiving line RX and a data transmitting line TX. The VCC pin of the second connector 50 is connected to the VCC power line of the first power module 29, and the GND pin of the second connector 50 is connected to the GND line of the first power module 29 and grounded. The VCC pin of the second connector 50 is also connected to the corresponding group of voltage-reducing resistors 24 and the corresponding group of analog-to-digital converters 23 via the VCC power line of the first power module 29.

[0079] refer to Figure 5The electric field generator 30 includes a second power supply module 31, a second controller 32, an AC signal generator 34, a second communication unit 33, and a set of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected to the VCC power line of the second power supply module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power supply module 31. The second power supply module 31 is also connected to and supplies power to the second controller 32 and the AC signal generator 34, respectively. The second communication unit 33 is electrically connected to the wire 5 of the second connector 50 through its data receiving line RX and to the wire 6 of the second connector 50 through its data transmitting line TX, thereby enabling information exchange between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected to the second communication unit 33, the AC signal generator 34, and a set of AC signal switches 35. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in the set of AC signal switches 35 and adjust the relevant parameters of the AC signal applied by the AC signal generator 34 according to the relevant digital signals received from the adapter 20 by the second communication unit 33. The relevant parameters of the AC signal include the voltage, current, and power of the AC signal. The AC signal generator 34 is electrically connected to several wires 1, 2, 3, and 4 of the second connector 50 through the set of AC signal switches 35. The set of AC signal switches 35 includes multiple AC signal switches 35, and the multiple AC signal switches 35 are arranged one-to-one with multiple electrode plates 10. Each AC signal switch 35 is electrically connected to a corresponding wire 1, 2, 3, or 4 of the second connector 50 through an AC signal wiring 36, and is also electrically connected to the corresponding electrode plate 10 through the corresponding wires 1, 2, 3, and 4 of the second connector 50, so as to transmit an AC signal to each electrode plate 10. The AC signal generator 34 is electrically connected to the AC signal switch 35 via a set of AC signal wiring 36.

[0080] Specifically, the number of AC signal switches 35 in the electric field generator 30 is related to the number of electrode plates 10. In this embodiment, the number of AC signal switches 35 is equal to the number of electrode plates 10, and both are four. The AC signal switches 35 include a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, and a fourth AC signal switch 35-4, which are electrically connected to the wires 1 to 4 of the second connector 50 respectively.One end of the first AC signal switch 35-1 is electrically connected to the AC signal generator 34 via the first AC signal wiring 36 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 1 in the second connector 50 via the first AC signal wiring 36-1, and to the AC signal line 28 located at port X1 of the adapter 20 via the wire 1 of the second connector 50. The AC signal line 28 located at port X1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 located at port X1 of the adapter 20 is electrically connected to the corresponding electrode plate 10, so as to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port X1 of the adapter 20; One end of the second AC signal switch 35-2 is electrically connected to the AC signal generator 34 via the second AC signal wiring 36 of the electric field generator 30. The other end is electrically connected to the corresponding AC signal transmission wire 2 in the second connector 50 via the second AC signal wiring 36-2, and then electrically connected to the AC signal line 28 at port Y1 of the adapter 20 via the wire 2 of the second connector 50. The AC signal line 28 at port Y1 of the adapter 20 is electrically connected to the first connector 40. The first connector 40 at port Y1 of the adapter 20 is electrically connected to the corresponding electrode plate 10, so as to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port Y1 of the adapter 20. One end of the three AC signal switch 35-3 is electrically connected to the AC signal generator 34 via the third AC signal wiring 36-3 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 3 in the second connector 50 via the AC signal wiring 36-3, and is electrically connected to the AC signal line 28 located at port X2 of the adapter 20 via the wire 3 of the second connector 50, the AC signal line 28 located at port X2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 located at port X2 of the adapter 20 is electrically connected to the corresponding electrode plate 10, so as to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port X2 of the adapter 20; Fourth One end of the AC signal switch 35-4 is electrically connected to the AC signal generator 34 via the fourth AC signal wiring 36-4 of the electric field generator 30, and the other end is electrically connected to the corresponding AC signal transmission wire 4 in the second connector 50 via the fourth AC signal wiring 36-4, and is electrically connected to the AC signal line 28 located at port Y2 of the adapter 20 via the wire 4 of the second connector 50. The AC signal line 28 located at port Y2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 located at port Y2 of the adapter 20 is electrically connected to the corresponding electrode plate 10, so as to control whether the AC signal generator 34 transmits AC signal to the electrode plate 10 electrically connected to port Y1 of the adapter 20.

[0081] The working principle of the handshake chip 17 is described in detail below. The handshake chip 17 can store electrical energy when the communication line 172 transmits a high level, and release energy when the communication line 172 transmits a low level, through an external energy storage element (not shown). This ensures that the handshake chip 17 has sufficient power to operate normally. Optionally, the energy storage element is a capacitor. In this way, the handshake chip 17 only requires one additional communication core wire to operate normally. The handshake chip 17 is suitable for handshake communication with external devices such as the electric field generator 30 or the adapter 20 to determine the connection status of each pair of electrode plates 10. After the handshake chip 17 completes handshake communication with the adapter 20 and / or the electric field generator 30, the state of the bidirectional switching switch 26 and the grounding switch 25 can be configured to apply an AC signal to the electrode plate 10 or to collect temperature data. When the electrode 10 needs to acquire or measure temperature, all bidirectional switches 26 on the flexible circuit board 11 of the electrode 10 are located at the sampling end 1. The electric field generator 30 or the adapter 20 can sequentially close each grounding switch 25 so that the analog temperature signal of the corresponding temperature sensor 14 in each row group is simultaneously sampled by the corresponding temperature sampling point. The analog temperature signal detected by each sampled temperature sensor 14 can also be converted into a signal that can characterize the type of the electrode 10 if the electrode 10 is qualified, or it can be used to characterize whether the electrode 10 has a temperature anomaly.

[0082] Specifically, when the first controller 22 of the adapter 20 receives the handshake signal sent by the electric field generator 30, it controls the corresponding grounding switch 25 connected to the grounding pin of the handshake chip 17 to close, so that the handshake chip 17 is powered on and sends the handshake signal to the handshake chip 17. The handshake chip 17 sends a feedback signal, and the first controller 22 on the adapter 20 sends the feedback signal of the handshake chip 17 to the second controller 32 of the electric field generator 30 through the second connector 50. The second controller 32 determines whether the corresponding first controller 22 and the handshake chip 17 have completed handshake communication based on the feedback signal of the handshake chip 17, and after the handshake communication is completed, it configures the state of each grounding switch 25 and each bidirectional switching switch 26 in the switch unit (unlabeled) on the adapter 20 to transmit AC signals to the dielectric elements of each electrode unit 12 of the electrode sheet 10 or to measure the temperature through the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10. When the electrode 10 is in temperature acquisition mode, the electric field generator 30 controls each bidirectional switching switch 26 of the adapter 20 through its second controller 32 to ensure that each bidirectional switching switch 26 is in its respective acquisition terminal 1, and sequentially closes each grounding switch 25, so that each detection channel of the corresponding analog-to-digital converter 23 acquires temperature detection signals from each temperature sensor 14 in a row, and performs analog-to-digital conversion on the acquired several temperature analog signals to obtain several AD sampling values, which correspond to digital temperature. The first controller 22 can also send several AD sampling values ​​to the electric field generator 30 through the adapter 20, so that if the electrode 10 is qualified, the electric field generator 30 can identify the type of the corresponding electrode 10 based on several AD sampling values, and / or, during the transmission of alternating electrical signals to the corresponding electrode 10, determine whether the corresponding electrode 10 has a temperature abnormality based on several AD sampling values.

[0083] The following will refer to Figures 3 to 5 The working principle of the tumor electric field therapy system 100 in this embodiment is described in detail.

[0084] The second controller 32 of the electric field generator 30 controls the grounding switch 25-4 corresponding to the fourth grounding line 18-4 connected to the handshake chip 17 of the electrode 10 to be in a closed state through the first controller 22 of the adapter 20. It also sends a handshake signal to the communication line 172 of the electrode 10 through the first controller 22, and determines the connection status between the electrode 10 and the adapter 20 based on whether feedback from the handshake chip 17 is received. If the electric field generator 30 receives a feedback signal from the electrode 10, it indicates that the connection between the electrode 10 and the adapter 20 is normal; then, an AC signal can be applied to the electrode 10, or a temperature detection signal can be acquired through the temperature sensor 14 of the electrode 10. If the electric field generator 30 does not receive a feedback signal from the electrode 10, it indicates that the connection between the electrode 10 and the adapter 20 is abnormal, and the second controller 32 of the electric field generator 30 issues a connection abnormality warning to alert the operator. After the operator handles the issue, the second controller 32 continues to control the first controller 22 of the adapter 20 to send a handshake communication signal to the handshake chip 17 of the electrode 10, repeating the above-mentioned operation of judging the connection status of the electrode 10 until the electrode 10 and the adapter 20 are connected normally.

[0085] When the electrode plate 10 is properly connected and the temperature of each electrode unit 12 of a certain electrode plate 10 needs to be detected, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the sampling terminal 1 of each of the multiple bidirectional switching switches 26 electrically connected to the electrode plate 10 to be turned on and the input terminal 2 to be turned off, so as to disconnect the AC signal applied to the electrode plate 10; at the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each of the grounding switches 25 electrically connected to the electrode plate 10 to be turned on in sequence. At this time, the temperature detection signals collected by each temperature sensor 14 of each electrode unit 12 in each row of the electrode plate 10 can be collected in sequence in time through the multiple detection channels A, B, C, D, E of the set of analog-to-digital converters 23 corresponding to the electrode plate 10. Each detection channel A, B, C, D, and E of each group of analog-to-digital converters 23 simultaneously acquires only the temperature detection signal of the temperature sensor 14 of the corresponding electrode unit 12 in the same row of electrode plates 10. This temperature detection signal can be characterized by a voltage value. Of the four grounding switches 25 corresponding to the electrode plate 10, only one can be on at any given time, while the other three are off. All five bidirectional switching switches 26 of the group of analog-to-digital converters 23 are switched to their respective sampling terminals 1, so that each dual-purpose signal line 19 of the electrode plate 10 is electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding analog-to-digital converter 23. With this configuration, the group of analog-to-digital converters 23 can acquire the voltage values ​​of all temperature sensors 14 of each electrode unit 12 in the same row of electrode plates 12 that are short-circuited to one grounding line 18 corresponding to the on-circuit grounding switch 25.

[0086] Specifically, when the first grounding switch 25-1 is closed, and the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group are energized, while the temperature sensors 14 of the electrode units 12-6 to 12-20 in the other row groups are de-energized. The electrode units 12-1, 12-6, 12-11, and 12-16 in the first detection channel A of the analog-to-digital converter 23 are short-circuited. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-1 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-6, 12-11, and 12-16 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the other temperature sensors 14 in the first row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-1. Therefore, only the temperature sensor 14 in electrode unit 12-1 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-1. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-2. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-3. The voltage value collected on the fourth detection channel D of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-4. The voltage value collected on the fifth detection channel E of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-5.

[0087] When the second grounding switch 25-2 is closed, and the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of the electrode units 12-6 to 12-10 in the second row group are energized, and the temperature sensors 14 of the electrode units 12-1 to 12-5 and the electrode units 12-11 to 12-20 in the other rows are de-energized. The electrode units 12-1, 12-6, 12-11, and 12-20 in the first detection channel A of the analog-to-digital converter 23 are short-circuited. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-6 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-1, 12-11, and 12-16 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the other temperature sensors 14 in the second row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-6. Therefore, only the temperature sensor 14 in electrode unit 12-6 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-6. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-7. The voltage value acquired on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-8. The voltage value acquired on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-9. The voltage value acquired on the fifth detection channel E of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-10.

[0088] When the third grounding switch 25-3 is closed, the first grounding switch 25-1, the second grounding switch 25-2, and the fourth grounding switch 25-4 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of the electrode units 12-11 to 12-15 in the third row group are energized, and the temperature sensors 14 of the electrode units 12-1 to 12-10 and the electrode units 12-16 to 12-20 in the other rows are de-energized. Electrode units 12-1, 12-6, 12-11, and 12-20 are short-circuited on the first detection channel A of the analog-to-digital converter 23 in this group. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-11 is connected to ground, while the grounding terminals 14-1 of the temperature sensor 14 in electrode units 12-1, 12-6, and 12-16 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the other temperature sensors 14 in the third row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-11. Therefore, only the temperature sensor 14 in electrode unit 12-11 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-11. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-12. The voltage value acquired on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-13. The voltage value acquired on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-14. The voltage value acquired on the fifth detection channel E of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of electrode unit 12-15.

[0089] When the fourth grounding switch 25-4 is closed, and the first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 are all open, and the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 are all switched to their respective sampling terminals 1, the temperature sensors 14 of electrode units 12-16 to 12-20 in the fourth row group are energized, while the temperature sensors 14 of electrode units 12-1 to 12-15 in the other rows are de-energized. The temperature sensors 14 of electrode units 12-1, 12-6, 12-11, and 12-16 in the first detection channel A of the analog-to-digital converter 23 are short-circuited. Since only the grounding terminal 14-1 of the temperature sensor 14 in electrode unit 12-16 is connected to ground, while the grounding terminals 14-1 of the temperature sensors 14 in electrode units 12-1, 12-6, and 12-11 are disconnected, and each electrode unit 12 has a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the fourth row will not affect the resistance value of the temperature sensor 14 in electrode unit 12-16. Therefore, only the temperature sensor 14 in electrode unit 12-16 is effectively operating on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 in electrode unit 12-16. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 in electrode unit 12-17. The voltage value acquired on the third detection channel C of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of electrode unit 12-18. The voltage value acquired on the fourth detection channel D of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of electrode unit 12-19. The voltage value acquired on the fifth detection channel E of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of electrode unit 12-20. Therefore, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 can acquire the temperature detection signals of the temperature sensors 14 of all electrode units 12 of a certain electrode piece 10 by controlling a set of bidirectional switching switches 26 and a set of grounding switches 25, which are all electrically connected to a certain electrode piece 10. Similarly, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of other electrode pieces 10 can be obtained.

[0090] The first controller 22, multiple sets of analog-to-digital converters 23, and multiple sets of bidirectional switching switches 26 can automatically perform operations through pre-programmed program code. For example, the first controller 22 first controls all bidirectional switching switches 26 in the corresponding set to switch to sampling terminal 1, so that all sampling terminals 1 of these bidirectional switching switches 26 are turned on and all input terminals 2 are turned off, so that each dual-purpose signal line 19 of the corresponding electrode plate 10 is electrically connected to the corresponding set of analog-to-digital converters 23. Then, it closes the first grounding switch 25-1 in the corresponding set of grounding switches 25, and opens the remaining second grounding switches 25-2, third grounding switches 25-3 to fourth grounding switches 25-4 in the set of grounding switches 25. During this period, the set of grounding switches 25... Each detection channel A, B, C, D, and E of the analog-to-digital converter 23 acquires the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the first row group of the corresponding electrode sheet 10, converts them into digital signals, and stores them in a separately provided memory. Then, after a preset interval, the first controller 22 closes the second grounding switch 25-2 in the group of grounding switches 25, and opens the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 in the group of grounding switches 25. During this period, each detection channel A, B, C, D, and E of the group of analog-to-digital converters 23 acquires the temperature detection signals of each temperature sensor 14 of each electrode unit 12 located in the second row group. By sequentially and individually turning on each grounding switch 25 in the group of grounding switches 25, the temperature detection signals of all temperature sensors 14 located in each row group of the electrode sheet 10 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature sensors 14 on at least one pair of electrode sheets 10 can be obtained.

[0091] The tumor electric field therapy system 100 of this application can achieve real-time and comprehensive temperature monitoring of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 or the number of wire cores in the first cable 13 electrically connected to the electrode sheet 10. It can then determine whether the electrode sheet 10 is qualified based on the obtained temperature detection signal; or determine whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14; or, if the electrode sheet is qualified, identify the electrode sheet type based on the obtained temperature detection signal; or, if the electrode sheet is qualified, determine whether the electrode unit 12 of the electrode sheet 10 is overheated based on the obtained temperature detection signal, and then control the alternating electrical signal applied to the electrode sheet 10 or the corresponding column of electrode units 12 of the electrode sheet 10, thereby avoiding low-temperature burns to the patient's skin during tumor treatment through the electrode sheet 10. Furthermore, the flexible circuit board 11 of the electrode sheet 10 of this application is electrically connected to the dielectric element 15 of the same electrode unit 12 and the signal terminal 14-2 of the temperature sensor 14 through the same dual-purpose signal line 19. This allows for the transmission of both AC signals and DC signals for temperature signal acquisition, as well as the acquired temperature detection signal, via the dual-purpose signal line 19. Simultaneously, it significantly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) laid on it, reducing the wiring difficulty of the flexible circuit board 11, simplifying the manufacturing process, reducing the weight of the flexible circuit board 11, and lowering manufacturing costs. The electrode sheet 10 of this application can also switch between applying AC signals for tumor treatment and transmitting DC signals for temperature acquisition and transmitting the acquired temperature detection signal through a combination of a grounding switch 25 electrically connected to the grounding line 18 and a bidirectional switching switch 26 electrically connected to the dual-purpose signal line 19.

[0092] When the electrode pad 10 is properly connected and an AC signal needs to be applied to the patient through each electrode unit 12 of a certain electrode pad 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls all the grounding switches 25 in a set of grounding switches 25 corresponding to the electrode pad 10 to be disconnected, and at the same time controls all the bidirectional switching switches 26 in a set of bidirectional switching switches 26 corresponding to the electrode pad 10 to be switched to their respective input terminals 2, so that the sampling terminals 1 of these bidirectional switching switches 26 are all disconnected and the input terminals 2 are all turned on, so that each dual-purpose signal line 19 of the electrode pad 10 is electrically connected to an AC signal line 28 corresponding to the adapter 20 and the electrode pad 10, thereby transmitting the AC signal to each electrode unit 12 of the electrode pad 10.When the temperature detection signals of the temperature sensors 14 of all electrode units 12 of the detected electrode plate 10 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32 to continue generating AC signals with increased or unchanged voltage or current amplitudes, which are then transmitted to the corresponding counter electrode plate 10 through a corresponding AC signal line 28 of the adapter 20, so that the counter electrode plate 10 continues to apply AC signals; when the temperature detection signals of the temperature sensors 14 of all electrode units 12 of the detected electrode plate 10 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, The electric field generator 30 can reduce the voltage or current of the AC signal generated by the AC signal generator 34 through the second controller 32, thereby reducing the voltage or current of the AC signal applied to the electrode plate 10. When the temperature detection signal of the temperature sensor 14 of an electrode unit 12 on a certain electrode plate 10 is detected to be greater than a preset temperature threshold, the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode plate 10 to disconnect through the second controller 32, so as to stop applying the AC signal to the electrode plate 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all the bidirectional switching switches in a group of bidirectional switching switches 26 electrically connected to the electrode plate 10. All bidirectional switches 26 are switched from their input terminals 2 to their sampling terminals 1, meaning that all bidirectional switching sampling terminals 1 of a set of bidirectional switches 26 electrically connected to the electrode 10 are turned on and all input terminals 2 are turned off, thereby stopping the application of alternating electrical signals to the electrode 10 for a certain period of time; or, when the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode 10 is detected to be greater than a preset temperature threshold, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode 10 to continue to be turned on, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls the bidirectional switching switch 35 electrically connected to the electrode unit 12 of the electrode 10 to continue to be turned on. Switch 26 switches from its input terminal 2 to its sampling terminal 1, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 simultaneously controls the input terminals 2 of the remaining bidirectional switches 26 that are electrically connected to the electrode units 12 in different columns from the electrode units 12 whose temperature detection signals do not exceed the preset temperature threshold. This stops applying AC signals to all electrode units 12 in the column where the temperature detection signals of the electrode unit 10 exceed the preset temperature threshold, and continues to apply AC signals to the remaining column electrode units 12 whose temperature detection signals do not exceed the preset temperature threshold. This realizes the control method of applying AC signals in a regional manner based on temperature detection signals in the tumor electric field therapy system 100.When an AC signal is applied, all grounding switches 25 are disconnected.

[0093] In this embodiment, the grounding switch 25, which is electrically connected to each of the multiple grounding lines 18 of the electrode plate 10, and the bidirectional switching switch 26, which is electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode plate 10, are both located in the adapter 20. However, in other embodiments, the grounding switch 25, which is electrically connected to the grounding line 18, and the bidirectional switching switch 26, which is electrically connected to the dual-purpose signal line 19, may also be located on the electrode plate 10 or in the electric field generator 30, which will not be elaborated here. In addition, the analog-to-digital converter 23 located in the adapter 20 may also be located in the electric field generator 30 and directly controlled by the second controller 32.

[0094] This application also provides other embodiments of the electrode sheet 10. The main differences between the multiple embodiments are the number of electrode units 12 and / or the circuit distribution of the electrode units 12, which will be described below.

[0095] Figure 6 This is a circuit connection diagram of the tumor electric field therapy system used in the second embodiment of this application, showing the electrode sheet 10D and... Figure 1 The circuit connection diagram of the adapter 20 of the first embodiment shown is illustrated below. The circuit description below uses the electrode plate 10D of the second embodiment as an example. In terms of electrical connection, the electrode plate 10D differs from the electrode plate 10 of the first embodiment in the number of electrode units 12 and the circuit arrangement. The electrode plate 10D in this embodiment has 13 of the aforementioned electrode units 12. In terms of electrical connection, the flexible circuit board 11D of the electrode plate 10D arranges these 13 electrode units 12 in three rows and five columns, with each of the two rows having 5 electrode units 12 and the remaining row having 3 electrode units 12. The flexible circuit board 11D of the electrode plate 10D is embedded with 3 ground lines 18, 5 dual-purpose signal lines 19, 1 ground trace 171 that is simultaneously connected to the ground pin of the handshake chip 17 and any ground line 28, and 1 communication line 172 that is connected to the communication pin of the handshake chip 17. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is used to short-circuit the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. One grounding line 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0096] The three grounding lines 18 of the flexible circuit board 11D are the first grounding line 18-1, the second grounding line 18-2, and the third grounding line 18-3. In the three rows of the electrode sheet 10D, the first row includes electrode units 12-1 to 12-5, the second row includes electrode units 12-6 to 12-10, and the third row includes electrode units 12-11 to 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-5 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-6 to electrode unit 12-10 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-11 to electrode unit 12-13 in the third row group and is also used to ground the grounding pin of the handshake chip 17 through the grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group, and one grounding wire 18 also short-circuits and grounds the grounding pin of the handshake chip 17.

[0097] The electrode sheet 10D has five dual-purpose signal lines 19, including a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-6, and electrode unit 12-11) and the signal terminal 14-2 of each of their respective temperature sensors 14. One end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-2, electrode unit 12-7, and electrode unit 12-12) and the signal terminal 14-2 of each of their respective temperature sensors 14. One end of the third dual-purpose signal line 19-3 is simultaneously connected to the electrode unit 12-4, electrode unit 12-5, electrode unit 12-6, and electrode unit 12-11. Each of the three electrode units 12 (12-8, 12-13) has its respective dielectric element 15 and the signal terminal 14-2 of its respective temperature sensor 14 connected to both electrode units 12-4 and 12-9. One end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 and the signal terminal 14-2 of both electrode units 12-5 and 12-10. In short, each dual-purpose signal line 19 short-circuits the dielectric element 15 and the signal terminal 14-2 of each electrode unit 12 located in a corresponding column group and connects them to the adapter 20.

[0098] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode plate 10D respectively via the first connector 40D. The fourth grounding switch 25-4 is in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10D respectively via the first connector 40D. A communication transmission line 211 on the adapter 20 is electrically connected to the communication line 172 connected to the communication pin of the handshake chip 17 of the electrode plate 10D.

[0099] The tumor electric field therapy system formed by electrode 10D, adapter 20 and electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. The second controller 32 of electric field generator 30 sends a handshake communication signal to the first controller 22 of adapter 20, and closes the third grounding switch 25-3 electrically connected to the handshake chip 17 of electrode 10 through the first controller 22 of adapter 20 or by directly controlling it. The handshake chip 17 is powered on. At this time, the first controller 22 sends a handshake communication signal to the handshake chip, and confirms that the electrode 10 is connected normally after receiving the feedback signal from the handshake chip 17. If no feedback signal is received from the handshake chip 17, it is confirmed that the electrode 10 is connected abnormally. When the electrode plate 10 is properly connected, the electric field transmitter 30 or the adapter 20 controls 1) all grounding switches 25 to be completely disconnected and all bidirectional switching switches 26 to have their input terminals 2 and sampling terminals 1 disconnected, so that all dual-purpose signal lines 19 and AC signal lines 28 are connected. At this time, all electrode units 12 of the electrode plate 10 can apply AC signals; 2) all bidirectional switching switches 26 have their sampling terminals 1 and input terminals 2 disconnected, and each grounding switch 25 is turned on in sequence, so that the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row of the electrode plate 10 can be obtained in sequence. Among them, no operation is required for the grounding switches 25 that are in the idle disconnected state.

[0100] refer to Figure 7 The diagram shown is a circuit connection schematic of the tumor electric field therapy system according to the third embodiment of this application, showing the electrode plate 10E and... Figure 1 The diagram shows a circuit connection of the adapter 20. The electrode plate 10E, like the electrode plate 10D in the second embodiment, has 13 electrode units 12, but the specific circuit arrangement is different. The flexible circuit board 11E of the electrode plate 10E also arranges these 13 electrode units 12 in three rows and five columns, except that two rows each have four electrode units 12, and the remaining row has five electrode units 12. The flexible circuit board 11E of the electrode plate 10E also embeds three grounding lines 18, five dual-purpose signal lines 19, one grounding trace 171 connected to both the grounding pin of the handshake chip 17 and any one of the grounding lines 28, and one communication line 172 connected to the communication pin of the handshake chip 17. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is used to short-circuit the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. One grounding line 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0101] The three grounding lines 18 of the electrode sheet 10E include a first grounding line 18-1, a second grounding line 18-2, and a third grounding line 18-3. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, and the third row group includes electrode units 12-9 to 12-13. Specifically, the first grounding line 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to 12-4 in the first row group; the second grounding line 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to 12-8 in the second row group; and the third grounding line 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to 12-13 in the third row group, and grounds the grounding pins of the handshake chip 17 through a grounding trace 171 connected to the grounding pins of the handshake chip 17. In short, each grounding line 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group, and one of the grounding lines 18 also shorts and grounds the ground pin of the handshake chip 17.

[0102] The electrode sheet 10E has five dual-purpose signal lines 19, including a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-1, electrode unit 12-5, and electrode unit 12-9) and the signal terminal 14-2 of each of their respective temperature sensors 14. One end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode unit 12-2, electrode unit 12-6, and electrode unit 12-10) and the signal terminal 14-2 of each of their respective temperature sensors 14. One end of the third dual-purpose signal line 19-3 is simultaneously connected to the electrode unit 12... -3. The dielectric elements 15 of each of the three electrode units 12 (electrode units 12-7, 12-11) and the signal terminals 14-2 of their respective temperature sensors 14 are connected simultaneously. One end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 of each of the three electrode units 12 (electrode units 12-4, 12-8, 12-12) and the signal terminals 14-2 of their respective temperature sensors 14. One end of the fifth dual-purpose signal line 19-5 is connected to the dielectric elements 15 of each of the electrode units 12-13 and the signal terminals 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits the dielectric elements 15 and the signal terminals 14-2 of the respective temperature sensors 14 of each electrode unit 12 located in the corresponding column group and connects them to the adapter 20.

[0103] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode plate 10E respectively via the first connector 40E. The fourth grounding switch 25-4 is in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode plate 10E respectively via the first connector 40E. A communication transmission line 211 on the adapter 20 is electrically connected to the communication line 172 connected to the communication pin of the handshake chip 17 of the electrode plate 10E.

[0104] The tumor electric field therapy system formed by electrode 10E, adapter 20, and electric field generator 30 operates in the same manner as the aforementioned tumor electric field therapy system 100. After the electric field generator 30 controls the adapter 20 to complete handshake communication with the handshake chip 17 of electrode 10E and confirms that the electrode 10E is connected normally, when all grounding switches 25 are open and the input terminals 2 and sampling terminals 1 of all bidirectional switching switches 26 are closed, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and AC signals can be applied to all electrode units 12. When the sampling terminals 1 and input terminals 2 of all bidirectional switching switches 26 are closed, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25. Among them, no operation is required for the grounding switches 25 that are in the idle and open state.

[0105] refer to Figure 8As shown, the electrode sheet 10F of the fourth embodiment has 13 electrode units 12, similar to the electrode sheet 10D of the third embodiment, but the specific circuit layout is different. The flexible circuit board 11F of the electrode sheet 10F arranges these 13 electrode units 12 in four rows and four columns, with three rows each having four electrode units 12 and the remaining row having one electrode unit 12. The electrode sheet 10F includes four grounding lines 18, four dual-purpose signal lines 19, one grounding trace 171 connected to the grounding pin of the handshake chip 17 and any grounding line 28, and one communication line 172 connected to the communication pin of the handshake chip 17. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 shorts the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. A grounding line 18 connected to grounding trace 171 also grounds the grounding pin of handshake chip 17.

[0106] The four grounding wires 18 of the electrode sheet 10F include a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, and a fourth grounding wire 18-4. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, and the fourth row group includes electrode unit 12-13. Specifically, the first grounding wire 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to electrode unit 12-4 in the first row group; the second grounding wire 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-5 to electrode unit 12-8 in the second row group; the third grounding wire 18-3 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-9 to electrode unit 12-12 in the third row group; and the fourth grounding wire 18-4 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-13 in the fourth row group. The fourth grounding wire 18-4 is also connected to the grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding wire 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row group, and one of the grounding wires 18 also short-circuits and grounds the grounding pin of the handshake chip 17.

[0107] The four dual-purpose signal lines 19 of the electrode sheet 10F include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the four electrode units 12 (electrode units 12-1, 12-5, 12-9, and 12-13) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-2, 12-6, and 12-10) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-3, 12-7, and 12-11) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the three electrode units 12 (electrode units 12-4, 12-8, and 12-12) and the signal terminal 14-2 of each of their respective temperature sensors 14. In short, each dual-purpose signal line 19 shorts in parallel the signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of each electrode unit 12 located in the same column group and is used to connect to the adapter 20.

[0108] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 on the adapter 20 are electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode plate 10F, respectively, via the first connector 40F. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4, respectively, via the first connector 40F. The fifth bidirectional switching switch 26-5 is in an idle and disconnected state. A communication transmission line 211 on the adapter 20 is electrically connected to the communication line 172, which is connected to the communication pin of the handshake chip 17 of the electrode plate 10F.

[0109] The tumor electric field therapy system formed by electrode 10F, adapter 20, and electric field generator 30 operates in the same manner as the aforementioned tumor electric field therapy system 100. After handshaking communication is completed with the first controller 22 of adapter 20 via handshaking chip 17 and the connection of electrode 10F is confirmed to be normal, when all grounding switches 25 are open and the input terminals 2 of all bidirectional switching switches 26 are closed, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the sampling terminals 1 of all bidirectional switching switches 26 are closed, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25 in sequence. No operation is required for the grounding switches 25 and / or the bidirectional switching switches 26 that are idle.

[0110] refer to Figure 9 The diagram shows a circuit connection schematic of the electrode sheet and adapter 20 in another embodiment of the tumor electric field therapy system of this application. The difference between the electrode sheet 10H in this embodiment and the aforementioned electrode sheet lies in the number of electrode units 12 and their arrangement in the circuit connection. In this embodiment, the electrode sheet 10H has nine electrode units 12. The flexible circuit board 11H of the electrode sheet 10H arranges these nine electrode units 12 in two rows and five columns, with one row having five electrode units 12 and the other row having four electrode units 12. The flexible circuit board 11H of the electrode sheet 10H embeds two grounding lines 18, five dual-purpose signal lines 19, one grounding trace 171 connected to both the grounding pin of the handshake chip 17 and any one of the grounding lines 28, and one communication line 172 connected to the communication pin of the handshake chip 17. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. One grounding line 18 is also used to ground the grounding pin of the handshake chip 17. Each dual-purpose signal line 19 is short-circuited to the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals.

[0111] The electrode plate 10H has two grounding lines 18, namely the first grounding line 18-1 and the second grounding line 18-2. In the two rows of the electrode plate 10H, the first row includes electrode units 12-1 to 12-5, and the second row includes electrode units 12-6 to 12-9. Specifically, the first grounding line 18-1 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-1 to 12-5 in the first row; the second grounding line 18-2 is used to ground the grounding terminals 14-1 of the temperature sensors 14 of each electrode unit 12-6 to 12-9 in the second row, and simultaneously grounds the grounding pin of the handshake chip 17 through a grounding trace 171 connected to the grounding pin of the handshake chip 17. In short, each grounding line 18 short-circuits and grounds the grounding terminals 14-1 of the temperature sensors 14 of all electrode units 12 in each row, and one grounding line 18 also grounds the grounding pin of the handshake chip 17.

[0112] The five dual-purpose signal lines 19 of the electrode sheet 10H include the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12 (electrode unit 12-1 and electrode unit 12-6) and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-2 and electrode unit 12-7 and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-3 and electrode unit 12-8 and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is simultaneously connected to the dielectric element 15 of each of the two electrode units 12-4 and electrode unit 12-9 and the signal terminal 14-2 of each of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of the electrode unit 12-5 and the signal terminal 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 shorts in parallel the signal terminals 14-2 of the dielectric elements 15 and temperature sensors 14 of each electrode unit 12 located in the corresponding column group and is used to connect to the adapter 20.

[0113] The first grounding switch 25-1 and the second grounding switch 25-2 on the adapter 20 are electrically connected to the first grounding wire 18-1 and the second grounding wire 18-2 of the electrode plate 10H respectively via the first connector 40H. The third grounding switch 25-3 and the fourth grounding switch 25-4 are in an idle and disconnected state. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 respectively via the first connector 40H. A communication transmission line 211 on the adapter 20 is electrically connected to the communication line 172 connected to the communication pin of the handshake chip 17 of the electrode plate 10H.

[0114] The tumor electric field therapy system formed by electrode 10H, adapter 20, and electric field generator 30 operates in the same way as the aforementioned tumor electric field therapy system 100. After the electric field generator 30 controls the adapter 20 to complete handshake communication with the handshake chip 17 of electrode 10E and confirms that electrode 10E is connected normally, when all grounding switches 25 are open and the input terminals 2 and sampling terminals 1 of all bidirectional switching switches 26 are closed, all dual-purpose signal lines 19 and AC signal lines 28 are connected, and all electrode units 12 are connected to AC signals. When the sampling terminals 1 and input terminals 2 of all bidirectional switching switches 26 are closed, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained sequentially by turning on each grounding switch 25. Among them, no operation is required for the grounding switches 25 that are in the idle and open state.

[0115] In the preceding embodiments, the number of grounding switches 25 corresponding to each electrode piece 10, 10D, 10E, 10F, and 10H of the adapter 20 is fixed at 4, and the number of bidirectional switching switches 26 corresponding to each electrode piece 10, 10D, 10E, 10F, and 10H is fixed at 5. This allows for the use of various electrode pieces 10, 10D, 10E, 10F, and 10H with different numbers of electrode units 12. However, in some cases, grounding switches 25 and / or bidirectional switching switches 26 may be in an idle / disconnected state, which can complicate the program control. To simplify the control program, specific adapters can be provided corresponding to the number of grounding wires 18 and dual-purpose signal lines 19 of the electrode pieces to avoid the occurrence of grounding switches 25 and / or bidirectional switching switches 26 in an idle / disconnected state, thus facilitating program control. That is, in other embodiments, the number of grounding switches 25 in each group of grounding switches 25 provided on the adapter 20 can be set according to the number of rows divided in the circuit connection of each electrode unit 12 of the corresponding electrode sheet, or according to the number of grounding wires 18 on the flexible circuit board of the corresponding electrode sheet; the number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 provided on the adapter 20 can be set according to the number of columns divided in the circuit connection of each electrode unit 12 of the corresponding electrode sheet, or according to the number of dual-purpose signal lines 19 on the flexible circuit board of the corresponding electrode sheet. Preferably, the number of grounding switches 25 in each group of grounding switches 25 of the adapter 20 is equal to the number of rows divided in the circuit connection of each electrode unit 12 of the corresponding electrode sheet, or equal to the number of grounding wires 18 on the flexible circuit board of the corresponding electrode sheet; the number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 provided on the adapter 20 is equal to the number of columns divided in the circuit connection of each electrode unit 12 of the corresponding electrode sheet, or equal to the number of dual-purpose signal lines 19 on the flexible circuit board of the corresponding electrode sheet.

[0116] The present invention also provides a method for temperature detection of electrode pad 10 in a tumor electric field therapy system 100, with reference to... Figure 10 As shown, the method includes:

[0117] Step S10: The connector 20 communicates with the handshake chip 17 of the electrode 10 to determine the connection status of the corresponding electrode 10.

[0118] Step S20: When the electrode plate 10 and the adapter 20 are connected normally, the adapter 20 is used to configure the switching states of each grounding switch 25 and each bidirectional switching switch 26 corresponding to the electrode plate 10, so that the temperature signals detected by each temperature sensor 14 in each row group can be sampled sequentially through the corresponding temperature sampling points.

[0119] The present invention also provides a method for identifying electrode types. The electrode type identification is performed when all temperature sensors on the electrode are normally connected. In addition to the steps S10 and S20 described above, the method further includes:

[0120] Step S30: Identify the type of the corresponding electrode 10 based on the temperature signals detected by all temperature sensors 14 of the sampled corresponding electrode 10.

[0121] In step S30, the temperature signals detected by all temperature sensors 14 corresponding to the electrode plate 10 are sampled and obtained as temperature analog signals. Step S30 specifically includes the following steps:

[0122] Step S301: Perform digital-to-analog conversion on all sampled temperature analog signals to obtain several AD sample values;

[0123] Step S302: Determine the number of electrode units 12 of the corresponding electrode sheet 10 based on several AD sampling values;

[0124] Step S303: Determine the type of the corresponding electrode sheet 10 according to the number of electrode units 12.

[0125] The present invention also provides a method for judging abnormal electrode temperature. The judgment of abnormal electrode temperature is performed during tumor electric field therapy by applying alternating current signals to each electrode unit of the electrode. In addition to the above-mentioned steps S10 and S20, the method also includes the following steps:

[0126] Step S40: Determine whether the corresponding electrode 10 has an abnormal temperature based on the temperature signals detected by all temperature sensors of the sampled corresponding electrode.

[0127] Step S40 specifically includes the following steps:

[0128] Step S401: Compare all sampled temperature signals with a preset temperature threshold;

[0129] Step S402: Determine whether there is a temperature abnormality in the electrode plate based on the comparison results.

[0130] The comparison results in step S402 include temperature signals that are less than a preset temperature threshold and temperature signals that are greater than or equal to a preset temperature threshold. Specifically, the temperature anomaly determination is as follows: if any of the sampled temperature signals is greater than or equal to the preset temperature threshold, the electrode temperature is determined to be abnormal; if all sampled temperature signals are less than the preset temperature threshold, the electrode temperature is determined to be normal. The preset temperature threshold is 39℃-44℃, preferably 41℃.

[0131] This invention also includes an alternating electrical signal regulation method, which, in addition to steps S10 and S20, further includes: regulating the alternating electrical signal applied to the corresponding electrode plate based on the temperature signals detected by all temperature sensors of the corresponding electrode plate. The regulation refers to adjusting the magnitude of the voltage, current, or power of the alternating electrical signal.

[0132] refer to Figure 11 As shown, the present invention also provides an electric field control method for the tumor electric field therapy system 100, the electric field control method comprising the following steps:

[0133] In step 101, the tumor electric field therapy system 100 is connected.

[0134] Specifically, the four electrode plates 10 are connected to the adapter 20, the adapter 20 is connected to the electric field generator 30, and the electric field generator 30 is connected to the appropriate power supply.

[0135] In step 102, it is detected whether the user has issued a command to turn on the electric field. If no command to turn on the electric field is detected, step 102 is repeated; if a command to turn on the electric field is detected, the process proceeds to step 103.

[0136] In step 103, after the electric field generator 30 of the tumor electric field therapy system 100 sends a handshake signal to the electrode 10 connected to the X1 port through the second connector 50, the adapter 20, and the first connector 40 connected to the X1 port, the first controller 22 of the adapter 20 receives the feedback signal from the electrode 10 of the X1 port through the corresponding communication transmission line 211 and determines whether the handshake is successful; if it is unsuccessful, proceed to step 105; if it is successful, proceed to step 106.

[0137] This judgment step can occur in the adapter 20 or the electric field generator 30; in this embodiment, it occurs in the adapter 20. Specifically, when the electrode 10 at the X1 port is properly connected, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 then determines that the handshake is successful. Conversely, when the electrode 10 at the X1 port is improperly connected, the first controller 22 of the adapter 20 does not receive the feedback signal from its handshake chip 17, and therefore determines that the handshake has failed.

[0138] In step 105, the tumor electric field therapy system 100 issues an alarm due to a failed handshake, and then proceeds to step 101.

[0139] In step 106, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the X2 port through the second connector 50, the adapter 20, and the first connector 40 connected to the X2 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode 10 of the X2 port through the corresponding communication transmission line 211, and determines whether the handshake is successful. If it fails, proceed to step 105; if it succeeds, proceed to step 107.

[0140] This judgment step can occur in the adapter 20 or the electric field generator 30; in this embodiment, it occurs in the adapter 20. Specifically, when the electrode plate 10 at the X2 port is properly connected, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 then determines that the handshake is successful. Conversely, when the electrode plate 10 at the X2 port is improperly connected, the first controller 22 of the adapter 20 does not receive the feedback signal from its handshake chip 17, and therefore determines that the handshake has failed.

[0141] In step 107, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the Y1 port through the second connector 50, the adapter 20, and the first connector 40 connected to the Y1 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode 10 of the Y1 port through the corresponding communication transmission line 211 and determines whether the handshake is successful. If it fails, proceed to step 105; if it succeeds, proceed to step 108.

[0142] This judgment step can occur in the adapter 20 or the electric field generator 30; in this embodiment, it occurs in the adapter 20. Specifically, when the electrode piece 10 at the Y1 port is properly connected, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 then determines that the handshake is successful. Conversely, when the electrode piece 10 at the Y1 port is improperly connected, the first controller 22 of the adapter 20 does not receive the feedback signal from its handshake chip 17, and therefore determines that the handshake has failed.

[0143] In step 108, after the electric field generator 30 sends a handshake signal to the electrode 10 connected to the Y2 port through the second connector 50, the adapter 20, and the first connector 40 connected to the Y2 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode 10 of the Y2 port through the corresponding communication transmission line 211 and determines whether the handshake is successful. If it fails, proceed to step 105; if it succeeds, proceed to step 109.

[0144] This judgment step can occur in the adapter 20 or the electric field generator 30; in this embodiment, it occurs in the adapter 20. Specifically, when the electrode 10 at the Y1 port is properly connected, its handshake chip 17 can receive the handshake request signal from the electric field generator 30 and feed back the handshake status to the first controller 22 of the adapter 20. The first controller 22 then determines that the handshake is successful. Conversely, when the electrode 10 at the Y2 port is improperly connected, the first controller 22 of the adapter 20 does not receive the feedback signal from its handshake chip 17, and therefore determines that the handshake has failed.

[0145] In steps 103, 106, 107, and 108 above, after receiving the handshake signal from the tumor electric field therapy system 100, the adapter 20 needs to control the corresponding grounding switch 25 and bidirectional switching switch 26 through the first controller 22. This closes the grounding switch 25 that is only electrically connected to the handshake chip 17, while all other grounding switches 24 are open, and the sampling terminals 1 and input terminals 2 of the corresponding bidirectional switching switches 26 are all turned on and off. This allows the handshake chip 17 to be electrically connected to the grounding pin GND of the adapter 20 through the first connector 40, so that the handshake chip 17 can work normally. If the electric field generator 30 and the adapter 20, the adapter 20 and the adapter 20, and the adapter 20 and the electrode 10 are all properly connected, then the handshake signal emitted by the electric field generator 30 can eventually reach the handshake chip 17 of the electrode 10, and the handshake status of the handshake chip 17 can be fed back to the electric field generator 30. If at least one connection abnormality occurs between the electric field generator 30 and the adapter 20, between the adapters 20 and each other, or between the adapter 20 and the electrode plate 10, the handshake chip 17 will fail to connect VCC and GND to form a circuit, resulting in the adapter 20 and the electric field generator 30 receiving an empty handshake status signal, thus causing the handshake to fail.

[0146] In step 109, the electric field generator 30 of the tumor electric field therapy system 100 sets the electric field parameters and then proceeds to step 110. The electric field parameters include the frequency, voltage, current, or power amplitude of the alternating electrical signal, etc.

[0147] In step 110, the adapter 20 sends temperature reading requests to the first connector 40 at the Y1 port and the first connector 40 at the Y2 port to collect temperature detection signals corresponding to a total of 40 temperature sensors 14 on the electrode plate 10 at the Y1 port and the electrode plate 10 at the Y2 port, and then proceeds to step 111.

[0148] In step 111, the tumor electric field therapy system 100 determines the type of electrode 10 at port Y1 and the electrode 10 at port Y2 by acquiring the temperature signal and then proceeds to step 112.

[0149] The type of electrode 10 at port Y1 and port Y2 is determined by analyzing the number of temperature detection signals acquired from the electrode 10 at port Y1 and port Y2, which in turn determines the number of temperature sensors 14 for each electrode 10. This determination process can occur in adapter 20 or electric field generator 30. In this embodiment, the electrode 10 has 20 temperature sensors 14, thus providing a total of 40 valid temperature signals.

[0150] In step 112, the tumor electric field therapy system 100 determines whether the temperature signal collected by the adapter 20 is abnormal. If it is abnormal, it proceeds to step 114. If all temperature signals are normal, it proceeds to step 113.

[0151] In step 113, the electric field generator 30 applies an alternating current signal to a pair of electrode plates 10 connected to ports Y1 and Y2, and at the same time stops applying an alternating current signal to a pair of electrode plates 10 connected to ports X1 and X2 and proceeds to step 115.

[0152] In step 114, the tumor electric field therapy system 100 alarms due to the presence of abnormal temperature signals of the electrode 10 connected to the Y1 port or the electrode 10 connected to the Y2 port, and then immediately proceeds to step 120.

[0153] In step 115, the adapter 20 sends temperature reading requests to the first connector 40 of port X1 and the first connector 40 of port X2 to collect the temperature signals of all temperature sensors 14 on the electrode plate 10 at port X1 and the electrode plate 10 at port X2, and then proceeds to step 116.

[0154] In step 116, the tumor electric field therapy system 100 determines the type of electrode 10 at port X1 and the electrode 10 at port X2 based on the temperature signal and then proceeds to step 117.

[0155] The type of electrode 10 at port X1 and port X2 is determined by the number of temperature sensors 14 connected to the electrode 10 at port X1 and port X2, respectively. This determination process can occur in adapter 20 or electric field generator 30. In this embodiment, the electrode 10 has 20 temperature sensors 14, thus providing a total of 40 valid temperature signals.

[0156] In step 117, the tumor electric field therapy system 100 determines whether the temperature signal collected by the adapter 20 is abnormal. If it is abnormal, it proceeds to step 114. If all 40 valid temperature signals are normal, it proceeds to step 118.

[0157] In step 118, the electric field generator 30 applies an alternating electrical signal to a pair of electrode plates 10 connected to ports X1 and X2, and simultaneously stops applying the alternating electrical signal to the pair of electrode plates 10 connected to ports Y1 and Y2, and proceeds to step 119. The total time for steps 113, 115, 116, 117 to 118 is fixed at 1 second.

[0158] In step 119, the tumor electric field therapy system 100 performs subsequent steps based on whether it has received a user's command to turn off the electric field. If a command to turn off the electric field is detected, it proceeds to step 120; if no command to turn off the electric field is detected, it proceeds to step 121.

[0159] In step 120, the tumor electric field therapy system 100 shuts down the electric field and proceeds to step 101. At this point, the electric field therapy ends, awaiting the next command to turn the electric field back on.

[0160] In step 121, the tumor electric field therapy system 100 determines whether the electric field parameters need to be adjusted based on the current electric field amplitude and the acquired temperature signal. If the electric field parameters need to be adjusted, it proceeds to step 109; otherwise, it proceeds to steps 110 to 119 in a loop. The total time for steps 118, 119, 121, 110, 111, 112, and 113 is fixed, which is 1 second in this embodiment. Thus, the tumor electric field therapy system 100 can continuously output alternating electric signals with a period of 2 seconds, alternating between applying an alternating electric signal in the first direction between a pair of electrodes 10 connected to ports X1 and X2 and an alternating electric signal in the second direction between another pair of electrode plates 10 connected to ports Y1 and Y2. Meanwhile, the tumor electric field therapy system 100 can reduce the time interval between turning off the alternating electric signal applied to a pair of electrode plates 10 connected to the X1 and X2 ports and turning on the alternating electric signal applied to another pair of electrode plates 10 connected to the Y1 and Y2 ports to 0s; and reduce the time interval between turning off the alternating electric signal applied to another pair of electrode plates 10 connected to the Y1 and Y2 ports and turning on the alternating electric signal applied to a pair of electrode plates 10 connected to the X1 and X2 ports to 0s, thereby extending the electric field therapy time while ensuring the accuracy of temperature acquisition.

[0161] This application also provides some temperature detection methods and AC signal application control methods, which are described below using electrode 10 as an example.

[0162] This application provides an electrode temperature detection method, applied to the electrode 10 or the tumor electric field therapy system 100 described above. Figure 12 As shown, it includes the following steps:

[0163] Step 210: When it is confirmed by the handshake chip that the electrode sheet is in a normal connection state, control each bidirectional switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to disconnect the alternating current signal applied to the dielectric element 15 of each electrode unit 12 of the electrode sheet 10, and at the same time connect the direct current signal applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10.

[0164] Step 220: Sequentially conduct the grounding switches 25 electrically connected to the grounding terminals 14-1 of the temperature sensors 14 of each row group electrode units 12 of the electrode sheet 10 at different time intervals to obtain the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of the electrode sheet 10.

[0165] Specifically, Step 210 is: control the bidirectional switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch from the end electrically connected to the alternating current signal to the end electrically connected to the direct current signal, that is, control the bidirectional switch 26 electrically connected to the electrode sheet 10 to switch from its input terminal 2 to its sampling terminal 1; or

[0166] Control the bidirectional switch 26 electrically connected to each electrode unit 12 of the electrode sheet 10 to switch the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 from the conducting state to the disconnected state, and at the same time switch the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 from the disconnected state to the conducting state.

[0167] By using the electrode sheet temperature detection method of the present application, the temperature detection signals of all electrode units of the electrode sheet can be obtained quickly and accurately; and it is possible to judge whether there is a fault, whether there is an abnormality, whether the electrode sheet is qualified, or whether it needs to be replaced according to the obtained temperature detection signals of all temperature sensors of the electrode sheet; it is also possible to judge whether there is overheating in each electrode unit of the electrode sheet according to the obtained temperature detection signals of all temperature sensors of the electrode sheet when the temperature sensors of the electrode sheet are normal, and then control the alternating current signal applied to the electrode sheet or each electrode unit of the electrode sheet; it is also possible to identify the type of electrode sheet when the temperature detection signals of each temperature sensor of the electrode sheet are normal.

[0168] See Figure 13 As shown, the embodiment of the present application further provides an alternating current signal application control method for tumor electrotherapy, which includes the above Step 210 and Step 220, and after Step 220, it further includes:

[0169] Step 260: When it is determined that the electrode sheet 10 does not need to be replaced, control or adjust the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 according to the obtained temperature detection signals of the temperature sensors 14 of each electrode unit 12 of the electrode sheet 10.

[0170] Step 260, controlling or adjusting the AC signal on each electrode unit 12 of the applied electrode sheet 10, further includes:

[0171] Step 261: When the temperature detection signals of each electrode unit 12 of the electrode sheet 10 do not exceed the preset temperature threshold, continue to apply AC signals to each electrode unit 12 of the electrode sheet 10; or

[0172] Step 262: When any temperature detection signal in the temperature detection signals of all electrode units 12 of the electrode sheet 10 exceeds a preset temperature threshold, stop applying AC signals to the electrode units 12 of the electrode sheet 10.

[0173] The step 262 of stopping the application of AC signals to the electrode units 12 of the electrode sheet 10 includes stopping the application of AC signals to all electrode units 12 of the electrode sheet 10, stopping the application of AC signals to the electrode units 12 in the electrode sheet 10 whose temperature detection signals exceed a preset temperature threshold, and stopping the application of AC signals to all electrode units 12 in the column of the electrode units 12 in the electrode sheet 10 whose temperature detection signals exceed the preset temperature threshold.

[0174] When the AC signal is stopped being applied to the electrode unit 12 in the electrode sheet 10 where the temperature detection signal exceeds the preset temperature threshold, the electrode unit 12 in the electrode sheet 10 where the temperature detection signal does not exceed the preset temperature threshold continues to be applied with an AC signal.

[0175] When the AC signal is stopped being applied to all electrode units 12 in the column where the temperature detection signal of the electrode unit 12 in the electrode sheet 10 exceeds the preset temperature threshold, the AC signal continues to be applied to all electrode units 12 in the electrode sheet 10 where the temperature detection signal does not exceed the preset temperature threshold and are in a different column from the electrode units 12 where the temperature detection signal exceeds the preset temperature threshold.

[0176] The process of continuing to apply an AC signal to the electrode plate 10 as described in step 261 is as follows:

[0177] Step 263: When the temperature detection signal is much lower than the preset temperature threshold, continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 by increasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10, or continue to apply the AC signal to each electrode unit 12 of the electrode sheet 10 by keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 constant; or

[0178] Step 264: When the temperature detection signal approaches the preset temperature threshold, continue to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 unchanged, or continue to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner that reduces the voltage or current amplitude of the alternating current signal applied to each electrode unit 12 of the electrode sheet 10.

[0179] Refer Figure 14 As shown, the present application also provides a signal control method for tumor electrotherapy, which is used for the above-mentioned electrode sheet 10. The method includes:

[0180] Step 310: Combine and control a group of ground switches 25 and a group of bidirectional switches 26 electrically connected to the corresponding electrode sheet 10 to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 and execute Step 320;

[0181] Step 320: Combine and control a group of ground switches 25 and a group of bidirectional switches 26 electrically connected to the electrode sheet 10 to collect the temperature detection signals of each electrode unit of the electrode sheet 10 in a row and execute Step 330;

[0182] Step 330: Determine the combined control mode of a group of ground switches 25 and a group of bidirectional switches 26 electrically connected to the electrode sheet 10 according to the collected temperature detection signals and execute Step 340;

[0183] Step 340: Control the working states of each electrode unit 12 of the electrode sheet 10 according to the determined combined control mode of the ground switch 25 and the bidirectional switch 26.

[0184] The working states of each electrode unit 12 of the electrode sheet 10 in Step 340 include: stopping applying the alternating current signal and continuing to collect the temperature detection signal, and stopping collecting the temperature detection signal and continuing to apply the alternating current signal. Continuing to apply the alternating current signal includes continuing to apply the alternating current signal in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal, continuing to apply the alternating current signal in a manner of keeping the voltage or current amplitude of the currently applied alternating current signal unchanged, and continuing to apply the alternating current signal in a manner of reducing the voltage or current amplitude of the currently applied alternating current signal.

[0185] The working states of each electrode unit 12 of the electrode sheet 10 are determined by the temperature detection signals collected by it. Each electrode unit 12 of the electrode sheet 10 is divided into different regions, and through the combined control of the ground switch 25 and the bidirectional switch 26, each electrode unit 12 in each region can cycle between applying the alternating current signal and collecting the temperature detection signal.

[0186] This application provides another method for detecting the temperature of electrode pads in a tumor electric field therapy system. Please refer to... Figure 15 As shown, taking electrode 10 as an example, the temperature detection method includes:

[0187] Step 510: Disconnect the AC signal input of the electrode 10, perform combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26, and acquire the temperature detection signal of the temperature sensor 14 of the electrode 10 corresponding to each combination.

[0188] Step 520: Sample and convert the temperature detection signal detected by each temperature sensor 14 in the electrode plate 10 to obtain a digital temperature signal;

[0189] Step 530: The digital temperature signal is transmitted to the electric field generator 30 of the tumor electric field therapy system 100 so that the electric field generator 30 can determine the temperature at the corresponding electrode unit 12 based on the digital temperature signal.

[0190] In step 510, "combined control of multiple grounding switches 25 and multiple bidirectional switching switches 26" specifically includes:

[0191] Step 511: Set all bidirectional switching switches 26 to sampling terminal 1 to connect the signal terminals 14-2 of each temperature sensor 14 of all electrode units 12 with the corresponding analog-to-digital converter 23.

[0192] Step 512: Sequentially close one of the multiple grounding switches 25 individually to collect the temperature detection signals detected by the temperature sensors 14 of each electrode unit 12 in the corresponding row group.

[0193] In step 512, closing one of the multiple grounding switches 25 in sequence at different times can activate the detection channel of the analog-to-digital converter 23, which is electrically connected to each temperature sensor 14 in the row group corresponding to the closed grounding switch 25.

[0194] Thus, the temperature detection signals of each temperature sensor 14 in each row group can be obtained sequentially, and then processed by the adapter 20 or the electric field generator 30 to obtain the temperature of all electrode units 12 on the electrode sheet 10; thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0195] The tumor electric field therapy system 100 of this application embodiment can also perform temperature detection on individual electrode units 12 as needed. The specific process for temperature detection of a specific electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the AC signal; place the bidirectional switch 26 corresponding to the column group containing the electrode unit 12 requiring individual temperature measurement at sampling terminal 1, and place the remaining bidirectional switches 26 at input terminal 2; simultaneously, turn on and ground the grounding switch 25 corresponding to the row group containing the electrode unit 12 requiring individual temperature measurement, and disconnect all other grounding switches 25. Thus, the temperature detection signal of the temperature sensor 14 in the electrode unit 12 requiring individual temperature measurement can be sampled to obtain the temperature of the electrode unit 12. For example, if the electrode unit 12 requiring individual temperature measurement is electrode unit 12-1, then the first bidirectional switch 26-1 corresponding to electrode unit 12-1 is placed at sampling terminal 1, and the remaining bidirectional switches (second bidirectional switch 26-2, second bidirectional switch 26-3, third bidirectional switch 26-3, and fourth bidirectional switch 26-4) are all placed at input terminal 2; simultaneously, the first grounding switch 25-1 corresponding to electrode unit 12-1 is closed and grounded, and the remaining grounding switches (second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4) are all opened. Thus, the temperature of electrode unit 12-1 can be detected.

[0196] This application also provides another method for applying an alternating current signal for tumor electric field therapy, applied to the above-mentioned tumor electric field therapy system, to... Figure 1 The following explanation uses the tumor electric field therapy system 100 as an example. Please refer to... Figure 16 As shown, the method for applying the alternating current signal includes:

[0197] Step 610: Determine the area in the electrode sheet 10 where the electrode unit 12 to which an AC signal needs to be applied is located;

[0198] Step 611: Combine multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to the electrode plate 10 to apply an AC signal.

[0199] In step 611, "the combination of multiple grounding switches 25 and multiple bidirectional switching switches 26 electrically connected to the electrode plate 10" specifically refers to:

[0200] Step 612: Disconnect all grounding switches 25 that are electrically connected to electrode plate 10;

[0201] Step 613: Determine the column group where the electrode unit 12 to which the AC signal needs to be applied is located, based on the area where the electrode unit 12 to which the AC signal needs to be applied is located;

[0202] Step 614: Determine the bidirectional switching switch 26 that is electrically connected to the electrode unit 12 in the column group where the electrode unit 12 that needs to be applied AC signal is located;

[0203] In step 610: The electrode sheet 10 is divided into regions of four adjacent electrode units 12. Each region's four electrode units 12 correspond to a column group, connected to a dual-purpose signal line 19 corresponding to the same bidirectional switching switch 26. In other embodiments, the electrode units 12 may be divided in other ways, which will not be described here.

[0204] Step 615: Control the bidirectional switch 26 electrically connected to the electrode unit 12 that needs to be applied with an AC signal to connect the electrode unit 12 that needs to be applied with an AC signal to the AC signal line 28 to apply an AC signal; at the same time, control the remaining bidirectional switches 26 to disconnect the electrical connection between each electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28, thereby stopping the application of AC signals.

[0205] In step 615, "connecting the electrode unit that needs to be applied with an AC signal to the AC signal line 28 to apply the AC signal and disconnecting the electrical connection between the electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28 to stop applying the AC signal" is achieved by placing the bidirectional switch 26, which is electrically connected to the electrode unit 12 in the column group corresponding to the area in the electrode sheet 10 where the AC signal needs to be applied, at its input terminal 2, and placing all the bidirectional switches 26, which are electrically connected to the electrode unit 12 in the remaining column groups, at the sampling terminal 1.

[0206] When the above methods are applied to electrode plates 10D, 10E, 10F and 10H in other embodiments, since there are grounding switches 25 and / or bidirectional switching switches 26 in an idle and disconnected state on the adapter 20 that are not electrically connected to the corresponding electrode plates 10D, 10E, 10F and 10H, the corresponding grounding switches 25 and / or bidirectional switching switches 26 in an idle and disconnected state do not need to be controlled.

[0207] Although the operations are depicted in the accompanying drawings in a specific order, this should not be construed as requiring that the operations be performed in the specific order shown or in chronological order, nor should it be construed as requiring that all the operations shown be performed to obtain the desired result.

[0208] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and not to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application, and they should all be covered within the scope of the claims and specification of this application. In particular, as long as there is no structural conflict, the various technical features mentioned in the embodiments can be combined in any way. This application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A tumor electric field therapy system, characterized in that, It includes: At least one pair of electrode sheets, each electrode sheet having a flexible circuit board, a plurality of electrode units disposed on the flexible circuit board, and a handshake chip, each electrode unit including a dielectric element and a temperature sensor having a signal terminal and a ground terminal, the flexible circuit board having multiple grounding lines connected to each of the ground terminals and multiple dual-purpose signal lines connected to each of the signal terminals, and the dielectric element of the same electrode unit being short-circuited to the signal terminal; and An electric field generator is provided, which has a second controller. The second controller sends a handshake signal to the handshake chip. After receiving the handshake signal, the handshake chip sends a feedback signal to the second controller. After receiving the feedback signal and confirming that the electrode plate is properly connected, the electric field generator transmits AC signals to each dielectric element through each of the dual-purpose signal lines in a first mode. In a second mode, it transmits DC signals or temperature signals detected by each temperature sensor to the signal terminals detected by each temperature sensor through each of the dual-purpose signal lines. In the second mode, each grounding wire is disconnected in the first mode and conductive in the second mode.

2. The tumor electric field therapy system according to claim 1, characterized in that, The electrode units are arranged in multiple rows and columns in the circuit. The grounding terminals of the temperature sensors in the same row group are all connected to the same grounding line. The grounding terminals of the temperature sensors in different row groups are connected in parallel through different grounding lines. In the second mode, the multiple grounding lines are turned on individually in sequence. The signal terminals of the temperature sensors in the same column group are all connected to the same dual-purpose signal line. The signal terminals of the temperature sensors in different column groups are connected in parallel through different dual-purpose signal lines.

3. The tumor electric field therapy system according to claim 2, characterized in that, The temperature signals detected by the temperature sensors are sampled line by line, and the sampled temperature signals detected by the temperature sensors are used to characterize the type of the electrode sheet or whether the electrode sheet has a temperature abnormality.

4. The tumor electric field therapy system according to claim 2, characterized in that, The electrode unit also includes a diode connected in series with the temperature sensor, and the temperature sensor is grounded through the diode.

5. The tumor electric field therapy system according to claim 2, characterized in that, The system also includes an adapter, which comprises multiple sets of bidirectional switching switches corresponding to each of the electrode plates. Each set of bidirectional switching switches is electrically connected to one of the multiple dual-purpose signal lines of the electrode plate. The adapter also includes an AC signal line and multiple sets of analog-to-digital converters corresponding to each of the electrode plates. Each set of analog-to-digital converters has multiple detection channels. The bidirectional switching switch has an input terminal electrically connected to the AC signal line and a sampling terminal electrically connected to the corresponding detection channel. The bidirectional switching switch switches between activating its input terminal and activating its sampling terminal, thereby switching the corresponding dual-purpose signal line between being connected to the AC signal line and being connected to the detection channel.

6. The tumor electric field therapy system according to claim 5, characterized in that, The adapter also includes multiple sets of grounding switches respectively corresponding to each of the electrode plates. Multiple grounding switches in each set are electrically connected to multiple grounding wires of the electrode plate and are configured to control the conduction or disconnection of the multiple grounding wires.

7. The tumor electric field therapy system according to claim 6, characterized in that, The adapter further includes a first controller, which is connected to multiple sets of grounding switches and multiple sets of bidirectional switching switches respectively. The first controller is configured to: in a second mode, configure the switching state of each grounding switch in the corresponding set of grounding switches to sequentially and individually turn on each of the grounding wires of the electrode sheet. And for controlling the switching state of each of the bidirectional switching switches in the corresponding group to connect each of the dual-purpose signal lines of the electrode sheet to the corresponding detection channel.

8. The tumor electric field therapy system according to claim 7, characterized in that, The first controller is configured to: upon receiving a handshake signal sent by the electric field generator, configure the switching state of the corresponding group of grounding switches and the switching state of the corresponding group of bidirectional switching switches to power on the handshake chip, send the handshake signal to the handshake chip, determine whether handshake communication with the handshake chip has been completed based on the feedback signal of the handshake chip, and after completing handshake communication, configure the switching state of each grounding switch in the corresponding group of grounding switches and the switching state of each bidirectional switching switch in the corresponding group of bidirectional switching switches to enable the corresponding group of analog-to-digital converters to sample the temperature signals detected by each temperature sensor in the corresponding row group.

9. The tumor electric field therapy system according to claim 8, characterized in that, The adapter further includes a first communication unit configured to acquire multiple sets of temperature signals collected by the analog-to-digital converter and send the temperature signals to the electric field generator. The electric field generator is further configured to control or adjust the AC signal applied to a corresponding electrode unit among the multiple electrode units of the electrode sheet according to the received temperature signals.

10. A temperature detection method, characterized in that, The method, applied to the tumor electric field therapy system as described in any one of claims 1-9, comprises the following steps: performing handshake communication with the handshake chip to determine the connection status of the corresponding electrode pads; when each electrode pad is normally connected, configuring the multiple dual-purpose signal lines of the electrode pads to be connected to the corresponding detection channels respectively, and configuring the multiple grounding lines to be sequentially and individually turned on, so as to sample the temperature signal detected by the electrode unit in each row group row by row.

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